{
    "JIfXICrQ": {
        "id": "JIfXICrQ",
        "title": "Analysis of volatile compounds and determination of key odors in Sichuan Paocai (Part \u2161)",
        "abstract": "Combined solid phase micro-extraction and gas chromatography-mass spectrometry(SPME-GC/MS) were taken to analyze the volatile components of Sichuan Paocai made with natural fermentation or artificial fermentation which is inoculated with old saline or lactic acid bacteria(LAB) starter cultures.Alcohols,aldehyde and alkene are the main volatiles of Sichuan Paocai,which amount 90% of the pickles' volatiles.Meanwhile key odors of Sichuan Paocai,sulfide,alkene and aldeyde are determined.Esters play only a limited role in the odor.There are big differences between natural fermented Sichuan Paocai and the artificial fermented Sichuan Paocai in the key odors.However,key odors of the artificial Sichuan Paocai inoculated with old saline or LAB starter cultures are similar.",
        "keywords": [
            "technology",
            "pickle",
            "Sichuan Paocai",
            "volatile compound",
            "artificial fermentation"
        ],
        "authors": [
            {
                "name": "CHEN Gong",
                "org": "Sichuan Academy of Food and Fermentation Industries,Insitute of Sichuan Paocai,Sichuan Paocai Functional Microorganism & Nutrition & Healthcare Research Center,Chengdu ,China"
            },
            {
                "name": "ZHANG Qisheng",
                "org": "Sichuan Academy of Food and Fermentation Industries,Insitute of Sichuan Paocai,Sichuan Paocai Functional Microorganism & Nutrition & Healthcare Research Center,Chengdu ,China"
            },
            {
                "name": "YU Wenhua",
                "org": "Sichuan Academy of Food and Fermentation Industries,Insitute of Sichuan Paocai,Sichuan Paocai Functional Microorganism & Nutrition & Healthcare Research Center,Chengdu ,China"
            },
            {
                "name": "LIU Zhu",
                "org": "Sichuan Academy of Food and Fermentation Industries,Insitute of Sichuan Paocai,Sichuan Paocai Functional Microorganism & Nutrition & Healthcare Research Center,Chengdu ,China"
            },
            {
                "name": "LI Heng",
                "org": "Sichuan Academy of Food and Fermentation Industries,Insitute of Sichuan Paocai,Sichuan Paocai Functional Microorganism & Nutrition & Healthcare Research Center,Chengdu ,China"
            },
            {
                "name": "YOU Jinggang",
                "org": "Sichuan Academy of Food and Fermentation Industries,Insitute of Sichuan Paocai,Sichuan Paocai Functional Microorganism & Nutrition & Healthcare Research Center,Chengdu ,China"
            }
        ],
        "venue": "China Brewing",
        "year": 2010
    },
    "qzbSeKfx": {
        "id": "qzbSeKfx",
        "title": "Color Retention Agent on the Color Effect of Lettuce Bubble",
        "abstract": "Based on the citric acid,glacial acetic acid,sodium erythorbate,sodium bicarbonate,of ferment lettuce independent and composite protecting color processing,In the process of fermentation the chlorophyll content and sensory evaluation of the lettuce were studied.The results show that: In the ferment lettuce add 4\u2030 sodium erythorbate and 5\u2030 of sodium bicarbonate compound effect best,Fermentation to twenty days,Chlorophyll content is 22.5mg/g,Chlorophyll loss rate 19.9%,Sensory is quality excellent.",
        "keywords": [
            "color retention",
            "ferment lettuce"
        ],
        "authors": [
            {
                "name": "ZHANG Ying",
                "org": ""
            },
            {
                "name": "YU Wen-hua",
                "org": ""
            },
            {
                "name": "YOU Jing-gang",
                "org": ""
            },
            {
                "name": "CHEN Gong",
                "org": ""
            },
            {
                "name": "ZHANG Qi-sheng",
                "org": ""
            },
            {
                "name": "LI Jie-zhi",
                "org": ""
            },
            {
                "name": "LI Heng",
                "org": ""
            },
            {
                "name": "LIU Zhu",
                "org": ""
            },
            {
                "name": "WU Qi-qian",
                "org": ""
            }
        ],
        "venue": "Food and Fermentation Technology",
        "year": 2013
    },
    "6Rdqk4Ea": {
        "id": "6Rdqk4Ea",
        "title": "Optimization of the Fermentation of Direct Vat Set Pickles",
        "abstract": "Dynamic changes of total acid in pickles brines were studied under different sugar content,direct vat set (DVS) contents,brines concentrations and fermentation temperature.Optimal fermentation conditions obtained through the dynamic changes and responsible-surface analysis methods as follows:inoculation of sugar of 1.5%,brine concentration 6.29%,inoculation of DVS 1.09%and fermentation temperature 30.8\u2103.Under such conditions,most total acid 0.75g/100ml was got.",
        "keywords": [
            "direct vat set",
            "pickles",
            "total acid",
            "responsible surface analysis"
        ],
        "authors": [
            {
                "name": "YU Wen-hua",
                "org": "Sichuan Academy of Food and Fermentation Industries,Chengdu "
            },
            {
                "name": "ZHANG Ying",
                "org": "Sichuan Academy of Food and Fermentation Industries,Chengdu "
            },
            {
                "name": "LIU Zhu",
                "org": "Sichuan Academy of Food and Fermentation Industries,Chengdu "
            },
            {
                "name": "ZHANG Qi-sheng",
                "org": "Sichuan Academy of Food and Fermentation Industries,Chengdu "
            },
            {
                "name": "CHEN Gong",
                "org": "Sichuan Academy of Food and Fermentation Industries,Chengdu "
            },
            {
                "name": "LI Jie-zhi",
                "org": "Sichuan Academy of Food and Fermentation Industries,Chengdu "
            },
            {
                "name": "WU Qi-qian",
                "org": "Sichuan Academy of Food and Fermentation Industries,Chengdu "
            },
            {
                "name": "LI Heng",
                "org": "Sichuan Academy of Food and Fermentation Industries,Chengdu "
            }
        ],
        "venue": "Food and Fermentation Technology",
        "year": 2010
    },
    "CWKAZ9jt": {
        "id": "CWKAZ9jt",
        "title": "Study on Extraction Process of Polyphenols Substance from Sichuan Pickles by Ultra Sound Wave",
        "abstract": "The purpose of the research was to Study the extraction process of polyphenols Substance from Sichuan pickles by ultra sound wave by using the orthogonal experiment on the basis of single factor experiment. The optimal condition was confirmed: the optimal ethanol concentration was 60%, the optimal temperature was 60\u2103, the optimal time was 45min and the proportion of raw material with extracting solvent was 1:20. By using the orthogonal design and variance analysis ,the order of the experimental factor was ethanol > concentration >the proportion of raw material with extracting solvent > extracting time.",
        "keywords": [
            "polyphenols",
            "ultra sound wave extraction",
            "Sichuan pickles"
        ],
        "authors": [
            {
                "name": "ZHANG Qi-sheng",
                "org": "Sichuan Academy of Food and Fermentation Industries, Functional Microbe and Nutrition Health Research Center for Sichuan Pickle,Chengdu "
            },
            {
                "name": "CHEN Gong",
                "org": "Sichuan Academy of Food and Fermentation Industries, Functional Microbe and Nutrition Health Research Center for Sichuan Pickle,Chengdu "
            },
            {
                "name": "YU Wen-hua",
                "org": "Sichuan Academy of Food and Fermentation Industries, Functional Microbe and Nutrition Health Research Center for Sichuan Pickle,Chengdu "
            },
            {
                "name": "LI Jie-zhi",
                "org": "Sichuan Academy of Food and Fermentation Industries, Functional Microbe and Nutrition Health Research Center for Sichuan Pickle,Chengdu "
            },
            {
                "name": "ZHANG Ying",
                "org": "Sichuan Academy of Food and Fermentation Industries, Functional Microbe and Nutrition Health Research Center for Sichuan Pickle,Chengdu "
            },
            {
                "name": "LI Heng",
                "org": "Sichuan Academy of Food and Fermentation Industries, Functional Microbe and Nutrition Health Research Center for Sichuan Pickle,Chengdu "
            }
        ],
        "venue": "Food and Fermentation Technology",
        "year": 2010
    },
    "Mteh3tmD": {
        "id": "Mteh3tmD",
        "title": "Discussion of Sichuan Pickles and pickle jars from the view of Chinese Pickles",
        "abstract": "Sichuan pickles can be called the Chinese quintessence,Large amounts of historical documents and archaeological evidences of pickle jars were cited and the long history of Chinese pickles and pickle jars were comprehensively discussed.Meanwhile,a new and realistic concept that salted vegetables is the prototype of pickles was proposed for the first time.The containers for the preparation of Sichuan pickles were discussed based on the analysis about production technology and pickles' characteristics.It is indicated that Sichuan pickles should be an outstanding representative of Chinese pickles.",
        "keywords": [
            "pickle jars",
            "lactic acid fermentation",
            "salted vegetables",
            "Sichuan pickles",
            "pottery urn"
        ],
        "authors": [
            {
                "name": "CHEN Gong",
                "org": "Sichuan Academy of Food and Fermentation Industries,Chengdu ,China"
            },
            {
                "name": "XIA Youshu",
                "org": "Sichuan Academy of Food and Fermentation Industries,Chengdu ,China"
            },
            {
                "name": "ZHANG Qisheng",
                "org": "Sichuan Academy of Food and Fermentation Industries,Chengdu ,China"
            },
            {
                "name": "LI Heng",
                "org": "Sichuan Academy of Food and Fermentation Industries,Chengdu ,China"
            },
            {
                "name": "YU Wenhua",
                "org": "Sichuan Academy of Food and Fermentation Industries,Chengdu ,China"
            }
        ],
        "venue": "China Brewing",
        "year": 2010
    },
    "ixYaBxx0": {
        "id": "ixYaBxx0",
        "title": "Study on Dynamic Changes during the Fermentation of Direct Vat Set Pickles",
        "abstract": "Dynamic changes of total acid,pH value,nitrite,amino acid were studied during the fermentation of various direct vat set pickles.The results showed that when the direct vat set cultures used in the fermentation of the pickles made from radish,cowpea,cabbage or potherb mustard at 30\u2103,the fermentation period,acid content,pH value and amino acid content were 3-4d,0.6-0.9g/100mL,3-4 and 4-7mg/mL,respectively.Meanwhile the nitrite content decreased significantly compared to the control that the pickles fermented without any direct vat set cultures.During the fermentation,the nitrite peak value was 7-16mg/Kg.The products made by direct vat set cultures taste well.",
        "keywords": [
            "amino acids",
            "pH value",
            "direct vat set culture",
            "pickles",
            "nitrite",
            "dynamic change",
            "acidity"
        ],
        "authors": [
            {
                "name": "YU Wen-hua",
                "org": ""
            },
            {
                "name": "ZHANG Qi-sheng",
                "org": ""
            },
            {
                "name": "CHEN Gong",
                "org": ""
            },
            {
                "name": "LIU Zhu",
                "org": ""
            },
            {
                "name": "ZHANG Ying",
                "org": ""
            },
            {
                "name": "LI Heng",
                "org": ""
            },
            {
                "name": "LI Jie-zhi",
                "org": ""
            },
            {
                "name": "WU Qi-qian",
                "org": ""
            }
        ],
        "venue": "Food and Fermentation Technology",
        "year": 2010
    },
    "aWZQaMor": {
        "id": "aWZQaMor",
        "title": "Study On Processing Technology Of Nutritional Sauerkraut",
        "abstract": "The pretreatment of raw materials and process technology in sauerkraut production process were studied and the effection of harvest time,salting method,salting time,salt consumption,cleaning,desalination,mixing materials,sterilization and storage processing on the selenium,iron and zinc content in Nutritional Sauerkrau was discussed.The optimum of parameters for the pretreatment of raw materials and process technology was determined: collection period: normal collection period,salting method: direct salting,salting time: 3 months,salt consumption: 7%,cleaning process: 5 times the water of salted materials cleaning for 20mins,desalination: 3times the water of salted materials cleaning for 30mins.In this way,the selenium,iron and zinc content in Nutritional Sauerkraut respectively reached 0.096\u00b10.001mg/kg,9.48\u00b10.25mg/kg,10.3\u00b10.68mg/kg,obviously higher than traditional Sauerkraut products.",
        "keywords": [
            "zinc",
            "selenium",
            "processing",
            "Nutritional Sauerkraut",
            "iron"
        ],
        "authors": [
            {
                "name": "LI Heng",
                "org": "Sichuan Academy of Food And Fermentation Industries,Chengdu ,China;Institute of Sichuan Paocai,Chengdu ,China"
            },
            {
                "name": "CHEN Gong",
                "org": "Sichuan Academy of Food And Fermentation Industries,Chengdu ,China;Institute of Sichuan Paocai,Chengdu ,China"
            },
            {
                "name": "LI Guo-bin",
                "org": "Sichuan Liji Pickle&Flavouring Co.Ltd.Meishan ,China"
            },
            {
                "name": "ZHANG Qi-sheng",
                "org": "Sichuan Academy of Food And Fermentation Industries,Chengdu ,China;Institute of Sichuan Paocai,Chengdu ,China"
            },
            {
                "name": "HU Tai-jian",
                "org": "Sichuan Liji Pickle&Flavouring Co.Ltd.Meishan ,China"
            },
            {
                "name": "YOU Jing-gang",
                "org": "Sichuan Academy of Food And Fermentation Industries,Chengdu ,China;Institute of Sichuan Paocai,Chengdu ,China"
            },
            {
                "name": "WAN Hu",
                "org": "Sichuan Liji Pickle&Flavouring Co.Ltd.Meishan ,China"
            },
            {
                "name": "WEI Wan-wen",
                "org": "Sichuan Liji Pickle&Flavouring Co.Ltd.Meishan ,China"
            },
            {
                "name": "YU Wen-hua",
                "org": "Sichuan Academy of Food And Fermentation Industries,Chengdu ,China;Institute of Sichuan Paocai,Chengdu ,China"
            }
        ],
        "venue": "Food and Fermentation Technology",
        "year": 2011
    },
    "1l8ryJfx": {
        "id": "1l8ryJfx",
        "title": "Study on Each Index Change of Direct Vat Set Function Bacteria during the Fermentation Process of Green Vegetables Saline",
        "abstract": "Key technologies during the fermentation process of pickled green vegetables using direct vat set(DVS) were studied.The changes of soluble solids,pH,lactic acid,amino nitrogen of green vegetables and saline water in saline fermentation process were detected.The saline fermentation parameters of green vegetables with direct vat set function bacteria were confirmed that: salt was added 6% ~ 8%;at the same time 0.04 \u2030direct vat set function bacteria was sprayed in a layer green vegetables;after one month saline treatment,lactic acid content reached above 0.6%,and the content of notrite gradually decreased to below 0.1 mg/Kg.By the saline fermentation way green vegetables were made as pickled vegetable with yellow-green color,crisp texture and good security.",
        "keywords": [
            "green vegetables",
            "saline fermentation",
            "direct vat set function bacteria"
        ],
        "authors": [
            {
                "name": "YU Wen-hua",
                "org": ""
            },
            {
                "name": "ZHANG Shu-yan",
                "org": ""
            },
            {
                "name": "CHEN Gong",
                "org": ""
            },
            {
                "name": "LIU Z",
                "org": ""
            },
            {
                "name": "LAN Heng-chao",
                "org": ""
            },
            {
                "name": "WAN Hu",
                "org": ""
            },
            {
                "name": "ZHANG Qi-sheng",
                "org": ""
            },
            {
                "name": "LI Jie-zhi",
                "org": ""
            },
            {
                "name": "ZHANG Y",
                "org": ""
            },
            {
                "name": "LI Heng",
                "org": ""
            }
        ],
        "venue": "Food and Fermentation Technology",
        "year": 2011
    },
    "IPWUldSE": {
        "id": "IPWUldSE",
        "title": "Pretreatment methods for the analysis of flavor compounds and determination of the main compositions in Sichuan Paocai",
        "abstract": "Flavors in Sichuan Paocai were extracted by organic reagent and solid phase micro-extraction,and then analyzed and determined with GC/MS.The results showed that solid micro-extraction and gas chromatography-mass spectrometry(SPME-GC/MS) was suitable for the determination of the flavors in Sichuan Paocai.The resource and composition of the flavors in Sichuan Paocai was determined by such methods.",
        "keywords": [
            "volatile compounds",
            "solid phase micro-extraction",
            "Sichuan Paocai",
            "fermentation",
            "flavors",
            "GC/MS"
        ],
        "authors": [
            {
                "name": "ZHANG Qi-sheng",
                "org": ""
            },
            {
                "name": "CHEN Gong",
                "org": ""
            },
            {
                "name": "YU Wen-hua",
                "org": ""
            },
            {
                "name": "LI Heng",
                "org": ""
            },
            {
                "name": "LIU Zhu",
                "org": ""
            },
            {
                "name": "ZHANG Ying",
                "org": ""
            },
            {
                "name": "LI Jie-zhi",
                "org": ""
            },
            {
                "name": "YOU Jing-gang",
                "org": ""
            }
        ],
        "venue": "Food and Fermentation Technology",
        "year": 2010
    },
    "bJEcNTKV": {
        "id": "bJEcNTKV",
        "title": "Study on Low Temperature Resistance Lactic Acid Bacteria Fermentation Paocai",
        "abstract": "The paocai was added 1\u2030 low temperature resistance lactic acid bacteria then fermented 29d at the temperature of 7\u00b11\u2103,the total acid concentration of the paocai was more than 0.6%.The time that nitrite peak appeared was postponed and the value of nitrite peak declined as the fermented temperature decreased when the low temperature resistance lactic acid bacteria was used to ferment paocai,in addition,the nitrite content of the sample was less than 2mg/kg when the fermentation was over,it was consistent with the existing hygienic requirements.",
        "keywords": [
            "ferment",
            "paocai",
            "low temperature resistance lactic acid bacteria"
        ],
        "authors": [
            {
                "name": "YU Wen-hua",
                "org": "Sichuan Academy of Food and Fermentation Industries,Chengdu ,China"
            },
            {
                "name": "DU Dan-qing",
                "org": "Sichuan Engineering Consulting and Research Institute,Chengdu ,China"
            },
            {
                "name": "ZHANG Ying",
                "org": "Sichuan Academy of Food and Fermentation Industries,Chengdu ,China"
            },
            {
                "name": "CHEN Gong",
                "org": "Sichuan Academy of Food and Fermentation Industries,Chengdu ,China"
            },
            {
                "name": "ZHANG Qi-sheng",
                "org": "Sichuan Academy of Food and Fermentation Industries,Chengdu ,China"
            },
            {
                "name": "LI Heng",
                "org": "Sichuan Academy of Food and Fermentation Industries,Chengdu ,China"
            },
            {
                "name": "LIU Zhu",
                "org": "Sichuan Academy of Food and Fermentation Industries,Chengdu ,China"
            }
        ],
        "venue": "Food and Fermentation Technology",
        "year": 2012
    },
    "SfGyR7nD": {
        "id": "SfGyR7nD",
        "title": "Study on Application of Low Temperature Resistant Lactobacillus in Saline Fermented Green Vegetable",
        "abstract": "Added l\u2030 low temperature resistant lactobacillus and 5-7% salt to the raw material of saline green vegetable, after one month saline treatment, the total acid content were more than 0.6% and the concentration of nitrite was below 1mg/kg.",
        "keywords": [
            "saline green vegetable",
            "low temperature resistant lactobacillus"
        ],
        "authors": [
            {
                "name": "YU Wen-hua",
                "org": ""
            },
            {
                "name": "CHEN Gong",
                "org": ""
            },
            {
                "name": "ZHANG Ying",
                "org": ""
            },
            {
                "name": "DU Dan-qing",
                "org": ""
            },
            {
                "name": "ZHANG Qi-sheng",
                "org": ""
            },
            {
                "name": "LI Heng",
                "org": ""
            },
            {
                "name": "LIU Zhu",
                "org": ""
            },
            {
                "name": "YOU Jing-gang",
                "org": ""
            }
        ],
        "venue": "Food and Fermentation Technology",
        "year": 2013
    },
    "ZVzoD0xV": {
        "id": "ZVzoD0xV",
        "title": "Research of Sichuan Paocai and lactic acid bacteria",
        "abstract": "Sichuan Paocai has a long history and is a typical representative of Chinese pickles.Its strong vitality was largely due to its unique microbial fermentation style.In this article,molecular microbial technology and traditional microbial technology were employed to study the distributions and changes of the microorganisms during the fermentation.The results showed that the lactic acid bacteria such as Leuconostoc mesenteroides,Lactobacillus plantarum,Lactobacillus brevis,etc.were dominant microorganisms during the Sichuan Paocai fermentation.In addition,the current situation of the Scihuan Paocai industries,classification of the Sichuan Paocai and the lactic acid bacteria was reviewed.",
        "keywords": [
            "lactic acid bacteria",
            "sichuan paocai",
            "dominant microorganisms"
        ],
        "authors": [
            {
                "name": "CHEN Gong",
                "org": "Sichuan Academy of Food and Fermentation Industries,Chengdu ,China;Sichuan Paocai Research institute,Chengdu ,China"
            },
            {
                "name": "YU Wenhua",
                "org": "Sichuan Academy of Food and Fermentation Industries,Chengdu ,China;Sichuan Paocai Research institute,Chengdu ,China"
            },
            {
                "name": "ZHANG Qisheng",
                "org": "Sichuan Academy of Food and Fermentation Industries,Chengdu ,China;Sichuan Paocai Research institute,Chengdu ,China"
            },
            {
                "name": "SONG Ping",
                "org": "Sichuan Microbiological Resources infrastructure & Culture Collection Center,Chengdu ,China"
            },
            {
                "name": "ZHANG Beibei",
                "org": "Sichuan Microbiological Resources infrastructure & Culture Collection Center,Chengdu ,China"
            },
            {
                "name": "LIU Zhu",
                "org": "Sichuan Academy of Food and Fermentation Industries,Chengdu ,China;Sichuan Paocai Research institute,Chengdu ,China"
            },
            {
                "name": "YOU Jinggang",
                "org": "Sichuan Academy of Food and Fermentation Industries,Chengdu ,China"
            },
            {
                "name": "LI Heng",
                "org": "Sichuan Academy of Food and Fermentation Industries,Chengdu ,China;Sichuan Paocai Research institute,Chengdu ,China"
            },
            {
                "name": "ZHANG Ying",
                "org": "Sichuan Academy of Food and Fermentation Industries,Chengdu ,China;Sichuan Paocai Research institute,Chengdu ,China"
            },
            {
                "name": "FENG Kuan",
                "org": "Sichuan Academy of Food and Fermentation Industries,Chengdu ,China;Sichuan Paocai Research institute,Chengdu ,China"
            }
        ],
        "venue": "China Brewing",
        "year": 2012
    },
    "paxXopnF": {
        "id": "paxXopnF",
        "title": "Study on Preparation of Toughness Biscuits Using Pickle Wastes Fiber Powder",
        "abstract": "The pickle wastes fiber powder was added to prepare toughness biscuits on the basis of basic recipe.The effects of grinding degree,additive amount of pickle wastes fiber powder,salt content of pickle wastes fiber powder,dosage of oil-sugar and dosage of leavening agent value on the dough properties and sensory quality were studied respectively by the way of single factor experiment.The orthogonal experiment was designed to determine the optimum formula for the pickle more than material fiber biscuits,The results showed that the optimum conditions for pickle wastes fiber biscuits were as follows:salt content of pickle wastes fiber powder 6%,grinding degree 100 list,flour 83g,pickle fiber power 17g,Composite porous agent 2.2g,oil11.5g,sugar 28.5g,an egg(50g),cream flavor 0.1g and dry yeast 1g.",
        "keywords": [
            "pickle wastes fiber powder",
            "optimum formula",
            "toughness biscuit"
        ],
        "authors": [
            {
                "name": "LI Jie-zhi",
                "org": "Sichuan Academy of Food & Fermentation Industries,Sichuan Pickle Institute,Wenjiang Chengdu ,China"
            },
            {
                "name": "CHEN Gong",
                "org": "Sichuan Academy of Food & Fermentation Industries,Sichuan Pickle Institute,Wenjiang Chengdu ,China"
            },
            {
                "name": "ZHANG Qi-sheng",
                "org": "Sichuan Academy of Food & Fermentation Industries,Sichuan Pickle Institute,Wenjiang Chengdu ,China"
            },
            {
                "name": "YU Wen-hua",
                "org": "Sichuan Academy of Food & Fermentation Industries,Sichuan Pickle Institute,Wenjiang Chengdu ,China"
            },
            {
                "name": "LI Heng",
                "org": "Sichuan Academy of Food & Fermentation Industries,Sichuan Pickle Institute,Wenjiang Chengdu ,China"
            },
            {
                "name": "WU Qi-qian",
                "org": "Sichuan Academy of Food & Fermentation Industries,Sichuan Pickle Institute,Wenjiang Chengdu ,China"
            }
        ],
        "venue": "Food and Fermentation Technology",
        "year": 2012
    },
    "TLyM4hMB": {
        "id": "TLyM4hMB",
        "title": "Effect of Direct Vat Set Lactobacillus on Intestinal Function in Mice with Constipation",
        "abstract": "To investigate the effect of direct vat set lactobacillus(DVSL) on intestinal function in mice with constipation. According to body weight, 50 male clean KM mice were randomly divided into five groups with 10 in each for the small intestinal movement experiment, which including control group, model group and the low,middle and high dosage group. Mice of the low, middle and high dosage group were respectively given the water solution of DVSL with 2.09, 4.17, 8.34\u00d7107CFU/mL at 0.2mL/10g body weight once a day, while mice of control group and model group were given water, each mouse was free access to diet and water, and the body weight of mice were recorded weekly. Mice of control group were given water, while that of model group and 3 dosage groups were compound dipheoxylate with 5mg/kg at the 15th day. Half an hour later, mice of control and model group were treated with ink, and that of the three dosage groups were the ink mixed with corresponding dose of DVSL respectively, the intestinal propulsive rate was measured after 25 minutes. According to the above methods,the time of the first black feces, the amount of feces within 6 hours and its weight were measured after mice were administrated compound dipheoxylate with 10mg/kg and ink in the defection experiment with 19 days. There were no statistical differences in body weight of mice in each group at different time(P >0.05). And the intestinal propulsive rate, the time of the first black feces, the amount of feces within 6 hours and its weight had statistical differences in mice of control group and model group(P<0.01), which suggested that mice constipation model was successfully established. The intestinal propulsive rate and the amount of feces within 6 hours of mice in middle dosage group were higher than that of model group(P <0.05), and the amount of feces within 6 hours and its weight of mice in high dosages group were higher than that of model group(P <0.01), while time of the first black feces was shorter(P<0.01). According to the Technical Standards for Testing & Assessment of Health Food(2003 edition), the solution of direct vast set lactobacillus has the regulation of intestinal function in mice with constipation.",
        "keywords": [
            "constipation",
            "direct vat set lactobacillus(DVSL)",
            "intestinal function"
        ],
        "authors": [
            {
                "name": "ZOU Hua-jun",
                "org": ""
            },
            {
                "name": "ZHANG Qi-sheng",
                "org": ""
            },
            {
                "name": "SHI Lei",
                "org": ""
            },
            {
                "name": "LI Heng",
                "org": ""
            },
            {
                "name": "XU Jia-yu",
                "org": ""
            },
            {
                "name": "HUANG Cheng-yu",
                "org": ""
            },
            {
                "name": "CHEN Gong",
                "org": ""
            },
            {
                "name": "LI Ming",
                "org": ""
            }
        ],
        "venue": "Food and Fermentation Technology",
        "year": 2013
    },
    "3PyUwFWn": {
        "id": "3PyUwFWn",
        "title": "Construction Partnering Process and Associated Critical Success Factors: Quantitative Investigation",
        "abstract": "",
        "keywords": [
            "construction",
            "construction industry",
            "project management",
            "critical success factor"
        ],
        "authors": [
            {
                "name": "Eddie W. L. Cheng",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            }
        ],
        "venue": "Journal of Management in Engineering",
        "year": 2002
    },
    "j69qTgdv": {
        "id": "j69qTgdv",
        "title": "Development of a Practical Model of Partnering for Construction Projects",
        "abstract": "",
        "keywords": [
            "construction management",
            "project management"
        ],
        "authors": [
            {
                "name": "Eddie W. L. Cheng",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            }
        ],
        "venue": "Journal of Construction Engineering and Management-asce",
        "year": 2004
    },
    "gf52DLQw": {
        "id": "gf52DLQw",
        "title": "Application of Barcode Technology for An Incentive Reward Program to Reduce Construction Wastes in Hong Kong",
        "abstract": "A group-based incentive reward program (IRP) has been implemented to minimize avoidable wastes of construction materials by rewarding workers according to the amounts and values of materials they saved. The barcode technique is used to facilitate the effective management of construction materials on site. An experiment is conducted on a residential project in Hong Kong and results from the experiment demonstrate the effectiveness of the IRP in motivating workers to reduce construction wastes. Discussions on the relationship between construction waste reduction and time and cost performances of the project are presented. Difficulties and challenges of applying the IRP and barcode technology are also included.",
        "keywords": [],
        "authors": [
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Zhen Chen",
                "org": ""
            },
            {
                "name": "Conrad T C Wong",
                "org": "Yau Lee Construction Co . , Ltd"
            }
        ],
        "venue": "",
        "year": 0
    },
    "QWQNQ8Rk": {
        "id": "QWQNQ8Rk",
        "title": "Establishment of Critical Success Factors for Construction Partnering",
        "abstract": "",
        "keywords": [
            "critical success factor",
            "evaluation",
            "cooperation",
            "management",
            "perception",
            "communications",
            "construction",
            "cost effectiveness",
            "project management"
        ],
        "authors": [
            {
                "name": "Eddie W. L. Cheng",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "P. E. D. Love",
                "org": ""
            }
        ],
        "venue": "Journal of Management in Engineering",
        "year": 2000
    },
    "aA4FOt2Y": {
        "id": "aA4FOt2Y",
        "title": "Network communication in the construction industry",
        "abstract": "",
        "keywords": [
            "communication channels",
            "project management",
            "communications",
            "information",
            "construction industry"
        ],
        "authors": [
            {
                "name": "Eddie W. L. Cheng",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Peter E. D. Love",
                "org": ""
            },
            {
                "name": "Zahir Irani",
                "org": ""
            }
        ],
        "venue": "Corporate Communications: An International Journal",
        "year": 2001
    },
    "oQwF7Nkf": {
        "id": "oQwF7Nkf",
        "title": "A generic conceptual framework for a Total Information Networking System in construction",
        "abstract": "",
        "keywords": [
            "construction",
            "system",
            "information",
            "network",
            "conceptual framework",
            "project management"
        ],
        "authors": [
            {
                "name": "Eddie W. L. Cheng",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Peter E. D. Love",
                "org": ""
            },
            {
                "name": "Zahir Irani",
                "org": ""
            }
        ],
        "venue": "IJSTM",
        "year": 2002
    },
    "DUwsnzaQ": {
        "id": "DUwsnzaQ",
        "title": "Analytic Network Process Applied to Project Selection",
        "abstract": "",
        "keywords": [
            "project management",
            "analytic network process",
            "network",
            "construction management",
            "construction industry"
        ],
        "authors": [
            {
                "name": "Eddie W. L. Cheng",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            }
        ],
        "venue": "Journal of Construction Engineering and Management-asce",
        "year": 2005
    },
    "TQu57HY6": {
        "id": "TQu57HY6",
        "title": "Narrowing the expectation gap of construction information technologies between academic preparation and industrial needs",
        "abstract": "",
        "keywords": [
            "information technology"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "David Scott",
                "org": ""
            },
            {
                "name": "Peter E. D. Love",
                "org": ""
            }
        ],
        "venue": "Computer Applications in Engineering Education",
        "year": 1999
    },
    "hJxbtVzP": {
        "id": "hJxbtVzP",
        "title": "Information priority-setting for better resource allocation using analytic hierarchy process (AHP)",
        "abstract": "",
        "keywords": [
            "resource allocation",
            "information system",
            "technology",
            "analytic hierarchy process",
            "analytical hierarchy process",
            "information systems",
            "information technology",
            "construction management"
        ],
        "authors": [
            {
                "name": "Eddie W. L. Cheng",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            }
        ],
        "venue": "Inf. Manag. Comput. Security",
        "year": 2001
    },
    "aeATV3dk": {
        "id": "aeATV3dk",
        "title": "Environmental Management of Urban Construction Projects in China",
        "abstract": "This paper presents a systematic approach to environmental management of pollution and/or hazards caused by urban construction projects in China. It proposes a qualitative approach to assess and control the problem and a method to calculate the Construction Pollution Index (CPI) which provides a quantitative measurement of pollution and/or hazards caused by the urban construction projects. Based on the analysis and discussions, the paper further proposes that major construction companies in China should obtain ISO 14001 Environmental Management System (EMS) certifications. By doing so, the construction companies can integrate the concept of environmental management into their construction management practice.",
        "keywords": [
            "project management",
            "iso 14000",
            "pollution management",
            "construction",
            "indexation",
            "pollution",
            "quantitative analysis",
            "construction management",
            "environmental management system",
            "china",
            "countermeasures",
            "qualitative analysis",
            "environmental management",
            "hazards",
            "civil engineering"
        ],
        "authors": [
            {
                "name": "Zhen Chen",
                "org": "Department of Building and Real Estate|Hong Kong Polytechnic University"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate|Hong Kong Polytechnic University"
            },
            {
                "name": "Conrad T. C. Wong",
                "org": "Yau Lee Construction Co Ltd"
            }
        ],
        "venue": "Journal of Construction Engineering and Management-asce",
        "year": 2000
    },
    "3D3lxENB": {
        "id": "3D3lxENB",
        "title": "Optimal Allocation of Construction Planning Resources",
        "abstract": "Efficient allocation of resources for construction planning activities requires construction planning resource requirements to be determined on a cost-effective and value-adding basis. However, although some research studies have indicated that increasing resource allocations to construction planning activities will lead to improved project performance, other research studies have indicated that investing in construction planning beyond an optimum point will lead to a deterioration in project performance. This study explored the concept of optimal planning of construction projects by examining 52 building projects undertaken in Australia. The relationships between planning input (ratio of planning costs to total project costs) and the probabilities of achieving poor performance and good performance were modeled using logistic, linear, and curvilinear regression analyses. A probable optimum planning input based on the sample studied was derived. It is suggested that any additional planning efforts beyond this optimum point would be essentially wasted because the additional plan- ning costs would not achieve any savings in project cost but merely add to the overhead costs and therefore increase the overall project cost. A model for optimal planning is presented and discussed.",
        "keywords": [
            "planning",
            "construction",
            "cost effectiveness",
            "value added",
            "resource allocation",
            "optimization",
            "regression analysis",
            "construction management"
        ],
        "authors": [
            {
                "name": "Olusegun O. Faniran",
                "org": ""
            },
            {
                "name": "Peter E. D. Love",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": "Dept . of Build"
            }
        ],
        "venue": "Journal of Construction Engineering and Management-asce",
        "year": 1999
    },
    "cOdBLqLv": {
        "id": "cOdBLqLv",
        "title": "Job Performance Evaluation for Construction Companies: An Analytic Network Process Approach",
        "abstract": "",
        "keywords": [
            "evaluation",
            "construction industry",
            "personnel management",
            "job performance",
            "analytic network process"
        ],
        "authors": [
            {
                "name": "Eddie W. L. Cheng",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            }
        ],
        "venue": "Journal of Construction Engineering and Management-asce",
        "year": 2006
    },
    "xqJvqxSU": {
        "id": "xqJvqxSU",
        "title": "Integrating construction pollution control with construction schedule: an experimental approach",
        "abstract": "A quantitative approach for managing construction pollution control that is based on construction resource leveling is presented. The parameters of construction pollution index (CPI), hazard magnitude ( i h ) are treated as a pseudo resource and integrated with a project's construction schedule. When the level of pollution for site operations exceeds the permissible limit identified by a regulatory body, a Genetic Algorithm (GA) enhanced leveling technique is used to re-schedule project activities so that the level of pollution can be re-distributed and thus reduced. The GA enhanced resource leveling technique is demonstrated using 20 on-site construction activities in a project. Experimental results indicate that proposed GA enhanced resource leveling method performs better than the traditional resource leveling method used in MS Project\u00a9. The proposed method is an effective tool that can be used by project managers to reduce the level of pollution at a particular period of time; when other control methods fail.",
        "keywords": [
            "control",
            "indexation",
            "genetic algorithm",
            "pollution"
        ],
        "authors": [
            {
                "name": "Zhen Chen",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Conrad T. C. Wong",
                "org": "Yau Lee Construction Co Ltd"
            },
            {
                "name": "Peter E. D. Love",
                "org": "Management Information Systems|Edith Cowan University"
            }
        ],
        "venue": "Environmental Management and Health",
        "year": 2002
    },
    "KEzbcJNL": {
        "id": "KEzbcJNL",
        "title": "Analytic hierarchy process (AHP): A defective tool when used improperly",
        "abstract": "",
        "keywords": [
            "analytic hierarchy process"
        ],
        "authors": [
            {
                "name": "Eddie W. L. Cheng",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Danny C. K. Ho",
                "org": ""
            }
        ],
        "venue": "Measuring Business Excellence",
        "year": 2002
    },
    "lbq2vHLC": {
        "id": "lbq2vHLC",
        "title": "Re-thinking TQM: toward a framework for facilitating learning and change in construction organizations",
        "abstract": "",
        "keywords": [
            "organizational learning",
            "construction industry",
            "adaptive learning",
            "tqm",
            "bpr"
        ],
        "authors": [
            {
                "name": "Peter E. D. Love",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Zahir Irani",
                "org": ""
            },
            {
                "name": "Gary D. Holt",
                "org": ""
            }
        ],
        "venue": "The Tqm Magazine",
        "year": 2000
    },
    "c7P4XoTP": {
        "id": "c7P4XoTP",
        "title": "A GIS-based site selection system for real estate projects",
        "abstract": "",
        "keywords": [
            "gis",
            "real estate",
            "geographic information system",
            "statistical model",
            "data envelope analysis",
            "real estate development"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Ling Yu",
                "org": ""
            },
            {
                "name": "Eddie W. L. Cheng",
                "org": ""
            }
        ],
        "venue": "Construction Innovation: Information, Process, Management",
        "year": 2005
    },
    "CLrMiZzK": {
        "id": "CLrMiZzK",
        "title": "Analytic hierarchy process: an approach to determine measures for business performance",
        "abstract": "",
        "keywords": [
            "analytic hierarchy process",
            "marketing strategy"
        ],
        "authors": [
            {
                "name": "Eddie W. L. Cheng",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            }
        ],
        "venue": "Measuring Business Excellence",
        "year": 2001
    },
    "1tGMjGLJ": {
        "id": "1tGMjGLJ",
        "title": "An empirical analysis of the barriers to implementing e-commerce in small-medium sized construction contractors in the state of Victoria, Australia",
        "abstract": "",
        "keywords": [
            "competitive advantage",
            "information and communication technology",
            "construction industry",
            "organizational performance",
            "e commerce"
        ],
        "authors": [
            {
                "name": "Peter E. D. Love",
                "org": ""
            },
            {
                "name": "Zahir Irani",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Eddie W. L. Cheng",
                "org": ""
            },
            {
                "name": "Raymond Y. C. Tse",
                "org": ""
            }
        ],
        "venue": "Construction Innovation: Information, Process, Management",
        "year": 2001
    },
    "qQOHCIio": {
        "id": "qQOHCIio",
        "title": "Site-Level Facilities Layout Using Genetic Algorithms",
        "abstract": "",
        "keywords": [
            "algorithms",
            "layout",
            "computation",
            "genetic algorithm",
            "genetic algorithms"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Peter E. D. Love",
                "org": ""
            }
        ],
        "venue": "Journal of Computing in Civil Engineering",
        "year": 1998
    },
    "Lg5JGKID": {
        "id": "Lg5JGKID",
        "title": "Barcode Technology for an Incentive Reward Program to Reduce Construction Wastes",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Zhen Chen",
                "org": ""
            },
            {
                "name": "Conrad T. C. Wong",
                "org": ""
            }
        ],
        "venue": "Computer-aided Civil and Infrastructure Engineering",
        "year": 2003
    },
    "CvBBql9r": {
        "id": "CvBBql9r",
        "title": "Cost modelling of office buildings in Hong Kong: an exploratory study",
        "abstract": "",
        "keywords": [
            "cross validation",
            "exploratory study",
            "design methodology",
            "cost estimation",
            "regression analysis",
            "price index",
            "regression model"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Q. P. Shen",
                "org": ""
            },
            {
                "name": "Peter E. D. Love",
                "org": ""
            }
        ],
        "venue": "Facilities",
        "year": 2005
    },
    "6Aj4K7zU": {
        "id": "6Aj4K7zU",
        "title": "Webfill before landfill: an e-commerce model for waste exchange in Hong Kong",
        "abstract": "",
        "keywords": [
            "e commerce",
            "simulation"
        ],
        "authors": [
            {
                "name": "Zhen Chen",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Conrad T. C. Wong",
                "org": ""
            }
        ],
        "venue": "Construction Innovation: Information, Process, Management",
        "year": 2003
    },
    "1T4KbPZL": {
        "id": "1T4KbPZL",
        "title": "A learning culture for strategic partnering in construction",
        "abstract": "",
        "keywords": [
            "supply chain",
            "organizational learning",
            "culture",
            "construction"
        ],
        "authors": [
            {
                "name": "Eddie W. L. Cheng",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Peter Love",
                "org": ""
            },
            {
                "name": "Zahir Irani",
                "org": ""
            }
        ],
        "venue": "Construction Innovation: Information, Process, Management",
        "year": 2004
    },
    "ZfSbG5ME": {
        "id": "ZfSbG5ME",
        "title": "Infrastructure of Partnering for Construction Projects",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Eddie W. L. Cheng",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "D. S. Drew",
                "org": ""
            },
            {
                "name": "Nicolas Yeung",
                "org": ""
            }
        ],
        "venue": "Journal of Management in Engineering",
        "year": 2001
    },
    "xn3xJkGU": {
        "id": "xn3xJkGU",
        "title": "Job Performance Dimensions for Improving Final Project Outcomes",
        "abstract": "",
        "keywords": [
            "project management",
            "construction management",
            "personnel management"
        ],
        "authors": [
            {
                "name": "Eddie W. L. Cheng",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Paul Fox",
                "org": ""
            }
        ],
        "venue": "Journal of Construction Engineering and Management-asce",
        "year": 2007
    },
    "vOXfpmya": {
        "id": "vOXfpmya",
        "title": "An e-business model to support supply chain activities in construction",
        "abstract": "",
        "keywords": [
            "competitive advantage",
            "value added",
            "supply chain",
            "information exchange",
            "electronic commerce",
            "e commerce",
            "construction industry",
            "business model"
        ],
        "authors": [
            {
                "name": "Eddie W. L. Cheng",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Peter E. D. Love",
                "org": ""
            },
            {
                "name": "Zahir Irani",
                "org": ""
            }
        ],
        "venue": "Logistics Information Management",
        "year": 2001
    },
    "tXcMMbqA": {
        "id": "tXcMMbqA",
        "title": "Triangulation in construction management research*",
        "abstract": "",
        "keywords": [
            "methodology",
            "triangulation",
            "construction management"
        ],
        "authors": [
            {
                "name": "Peter E. D. Love",
                "org": ""
            },
            {
                "name": "Gary D. Holt",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            }
        ],
        "venue": "Engineering, Construction and Architectural Management",
        "year": 2002
    },
    "kO2cILuX": {
        "id": "kO2cILuX",
        "title": "The IT performance evaluation in the construction industry",
        "abstract": "To date, there has been limited published work in the construction management and engineering literature that has provided empirical evidence to demonstrate that IT can improve organizational performance. Without an explicit understanding of how IT can be effectively used to improve organizational performance, its justification will remain weak for managers. To ensure the continuous increase in IT-based applications in the construction industry, sufficient evidence has to be provided for management in various professions of the construction industry to evaluate, allocate and utilize appropriate IT systems. In an attempt to explore the relationship between IT and productivity, an empirical investigation of 60 professional consulting firms from the Hong Kong construction industry was undertaken. A model for determining the organizational productivity of IT is proposed, and the methodology used to test the model is described. The findings are analyzed, and a cross-profession comparison of the results indicates the differences in the use of IT. The research findings are discussed, with similarities being drawn. The limitations of the research are then presented and discussed. The implications of the findings and conclusions are then fully presented.",
        "keywords": [
            "organizational performance",
            "construction management",
            "integration",
            "civil engineering computing",
            "information technology",
            "professional consulting firms",
            "decision-making",
            "it",
            "it-based applications",
            "survey.",
            "construction industry",
            "dp management",
            "organizational productivity",
            "hong kong",
            "complexity",
            "performance evaluation",
            "survey",
            "productivity",
            "cross-profession comparison",
            "it performance evaluation",
            "empirical evidence"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Zahir Irani",
                "org": ""
            },
            {
                "name": "Peter E. D. Love",
                "org": ""
            }
        ],
        "venue": "hawaii international conference on system sciences",
        "year": 2000
    },
    "5jSTs9Kp": {
        "id": "5jSTs9Kp",
        "title": "A quantitative approach to construction pollution control based on resource levelling",
        "abstract": "A quantitative approach for construction pollution control that is based on construction resource leveling is presented. The parameters of construction pollution index (CPI), hazard magnitude ( i h ) are treated as a pseudo resource and integrated with a project's construction schedule. When the level of pollution for site operations exceeds the permissible limit identified by a regulatory body, a Genetic Algorithm (GA) enhanced leveling technique is used to re-schedule project activities so that the level of pollution can be re-distributed and thus reduced. The GA enhanced resource leveling technique is demonstrated using 20 on-site construction activities in a project. Experimental results indicate that proposed GA enhanced resource leveling method performs better than the traditional resource leveling method used in MS Project\u00a9. The proposed method is an effective tool that can be used by project managers to reduce the level of pollution at a particular period of time; when other control methods fail.",
        "keywords": [
            "resource levelling",
            "genetic algorithm",
            "indexation"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate|Hong Kong Polytechnic University"
            },
            {
                "name": "Zhen Chen",
                "org": "Doctoral Candidate|Department of Building and Real Estate|Hong Kong Polytechnic University"
            },
            {
                "name": "Conrad T. C. Wong",
                "org": "Yau Lee Construction Co Ltd"
            },
            {
                "name": "Peter E. D. Love",
                "org": "School of Architecture and Building|Deakin University"
            }
        ],
        "venue": "Construction Innovation: Information, Process, Management",
        "year": 2002
    },
    "6cXZA7zu": {
        "id": "6cXZA7zu",
        "title": "A model for supporting inter-organizational relations in the supply chain",
        "abstract": "",
        "keywords": [
            "construction",
            "supply chain"
        ],
        "authors": [
            {
                "name": "Peter E. D. Love",
                "org": ""
            },
            {
                "name": "Zahir Irani",
                "org": ""
            },
            {
                "name": "Eddie Cheng",
                "org": ""
            },
            {
                "name": "Heng LI",
                "org": ""
            }
        ],
        "venue": "Engineering, Construction and Architectural Management",
        "year": 2002
    },
    "64dt0KiO": {
        "id": "64dt0KiO",
        "title": "Development of a conceptual model of construction partnering",
        "abstract": "",
        "keywords": [
            "conceptual model",
            "project",
            "construction",
            "critical success factor"
        ],
        "authors": [
            {
                "name": "Eddie W. L. Cheng",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            }
        ],
        "venue": "Engineering, Construction and Architectural Management",
        "year": 2001
    },
    "Hp3nVrFe": {
        "id": "Hp3nVrFe",
        "title": "The analytic network process (ANP) approach to location selection: a shopping mall illustration",
        "abstract": "",
        "keywords": [
            "mcdm",
            "ahp",
            "decision models",
            "analytic network process",
            "decision problem",
            "location",
            "analytic hierarchy process",
            "construction"
        ],
        "authors": [
            {
                "name": "Eddie W. L. Cheng",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Ling Yu",
                "org": ""
            }
        ],
        "venue": "Construction Innovation: Information, Process, Management",
        "year": 2005
    },
    "ZYLaDXzn": {
        "id": "ZYLaDXzn",
        "title": "MAQ: Mapping and Assembly with Qualities",
        "abstract": "The vast numbers of very short reads produced by new sequencing technologies such as Illumina GA and AB SOLiD pose a great challenge to data analysis. MAQ, which stands for Mapping and Assembly with Qualities, is a software for mapping short reads to diploid mammalian-sized genomes and calling variants. MAQ differs from most existing alignment software in several aspects. First, it calculates a mapping quality for each alignment, measuring the probability of the alignment being wrong. This greatly helps accurate variant calling. Second, it maps every read that has a match, placing repetitive reads randomly amongst equally good alternatives, but with a low mapping score, instead of discarding them. This avoids any ambiguity in defining \"unique\", and provides more data for the subsequent analysis. Third, MAQ aligns mate-pair reads in a sliding window, effectively examining proper paired positions with little computational effort, and allowing reads in repeats to be aligned with high confidence if their mates are in unique regions. Furthermore, MAQ calls the diploid genotype at each base position in the reference with a Phred-like quality, allowing the user to control the sensitivity/ specificity trade-off, and facilitating the use of MAQ calls in downstream analysis. MAQ has been used at multiple sites for human chromosome resequencing, human structural variation analysis, and multiple smaller genome variation studies. In addition to its key functionalities, MAQ can also call short indels, work with SOLiD data, simulate reads and comes with a fast graphic visualizer for the read alignments. Most of its functions come with user friendly interfaces and are well documented. It is available from http://maq.sourceforge.net.",
        "keywords": [],
        "authors": [
            {
                "name": "Heng Li",
                "org": "Beijing Genomics Institute"
            },
            {
                "name": "Jue Ruan",
                "org": "Beijing Genomics Institute"
            },
            {
                "name": "Richard Durbin",
                "org": "Beijing Genomics Institute"
            }
        ],
        "venue": "",
        "year": 0
    },
    "nYH9fszV": {
        "id": "nYH9fszV",
        "title": "pIRS: Profile-based Illumina pair-end reads simulator.",
        "abstract": "The next-generation high-throughput sequencing technologies, especially from Illumina, have been widely used in re-sequencing and de novo assembly studies. However, there is no existing software that can simulate Illumina reads with real error and quality distributions and coverage bias yet, which is very useful in relevant software development and study designing of sequencing projects.We provide a software package, pIRS (profile-based Illumina pair-end reads simulator), which simulates Illumina reads with empirical Base-Calling and GC%-depth profiles trained from real re-sequencing data. The error and quality distributions as well as coverage bias patterns of simulated reads using pIRS fit the properties of real sequencing data better than existing simulators. In addition, pIRS also comes with a tool to simulate the heterozygous diploid genomes.pIRS is written in C++ and Perl, and is freely available at ftp://ftp.genomics.org.cn/pub/pIRS/.",
        "keywords": [],
        "authors": [
            {
                "name": "Xuesong Hu",
                "org": ""
            },
            {
                "name": "Jianying Yuan",
                "org": ""
            },
            {
                "name": "Yujian Shi",
                "org": ""
            },
            {
                "name": "Jianliang Lu",
                "org": ""
            },
            {
                "name": "Binghang Liu",
                "org": ""
            },
            {
                "name": "Zhenyu Li",
                "org": ""
            },
            {
                "name": "Yanxiang Chen",
                "org": ""
            },
            {
                "name": "Desheng Mu",
                "org": ""
            },
            {
                "name": "Hao Zhang",
                "org": ""
            },
            {
                "name": "Nan Li",
                "org": ""
            },
            {
                "name": "Zhen Yue",
                "org": ""
            },
            {
                "name": "Fan Bai",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Wei Fan",
                "org": ""
            }
        ],
        "venue": "Bioinformatics",
        "year": 2012
    },
    "mRZkz6t7": {
        "id": "mRZkz6t7",
        "title": "Test Data Sets and Evaluation of Gene Prediction Programs on the Rice Genome",
        "abstract": "With several rice genome projects approaching completion gene prediction/finding by computer algorithms has become an urgent\n task. Two test sets were constructed by mapping the newly published 28,469 full-length KOME rice cDNA to the RGP BAC clone\n sequences of Oryza sativa ssp. japonica: a single-gene set of 550 sequences and a multi-gene set of 62 sequences with 271 genes. These data sets were used to evaluate\n five ab initio gene prediction programs: RiceHMM, GlimmerR, GeneMark, FGENSH and BGF. The predictions were compared on nucleotide, exon\n and whole gene structure levels using commonly accepted measures and several new measures. The test results show a progress\n in performance in chronological order. At the same time complementarity of the programs hints on the possibility of further\n improvement and on the feasibility of reaching better performance by combining several gene-finders.",
        "keywords": [
            "accuracy measures",
            "dynamic programming",
            "gene prediction",
            "hidden markov models",
            "rice genome",
            "test sets",
            "gene structure",
            "nucleotides"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": "Academia Sinica Beijing Genomics Institute (BGI) Beijing 101300 P.R. China Beijing 101300 P.R. China"
            },
            {
                "name": "Jin-song Liu",
                "org": "Academia Sinica Beijing Genomics Institute (BGI) Beijing 101300 P.R. China Beijing 101300 P.R. China"
            },
            {
                "name": "Zhao Xu",
                "org": "Academia Sinica Beijing Genomics Institute (BGI) Beijing 101300 P.R. China Beijing 101300 P.R. China"
            },
            {
                "name": "Jiao Jin",
                "org": "Academia Sinica Beijing Genomics Institute (BGI) Beijing 101300 P.R. China Beijing 101300 P.R. China"
            },
            {
                "name": "Lin Fang",
                "org": "Academia Sinica Beijing Genomics Institute (BGI) Beijing 101300 P.R. China Beijing 101300 P.R. China"
            },
            {
                "name": "Lei Gao",
                "org": "Academia Sinica Beijing Genomics Institute (BGI) Beijing 101300 P.R. China Beijing 101300 P.R. China"
            },
            {
                "name": "Yu-dong Li",
                "org": "Academia Sinica Beijing Genomics Institute (BGI) Beijing 101300 P.R. China Beijing 101300 P.R. China"
            },
            {
                "name": "Zi-xing Xing",
                "org": "Academia Sinica Beijing Genomics Institute (BGI) Beijing 101300 P.R. China Beijing 101300 P.R. China"
            },
            {
                "name": "Shao-gen Gao",
                "org": "Academia Sinica Beijing Genomics Institute (BGI) Beijing 101300 P.R. China Beijing 101300 P.R. China"
            },
            {
                "name": "Tao Liu",
                "org": "Academia Sinica Beijing Genomics Institute (BGI) Beijing 101300 P.R. China Beijing 101300 P.R. China"
            },
            {
                "name": "Hai-hong Li",
                "org": "Academia Sinica Beijing Genomics Institute (BGI) Beijing 101300 P.R. China Beijing 101300 P.R. China"
            },
            {
                "name": "Yan Li",
                "org": "Hangzhou Branch of BGI Hangzhou 310008 P.R. China Hangzhou 310008 P.R. China"
            },
            {
                "name": "Li-jun Fang",
                "org": "Hangzhou Branch of BGI Hangzhou 310008 P.R. China Hangzhou 310008 P.R. China"
            },
            {
                "name": "Hui-min Xie",
                "org": "Suzhou University Department of Mathematics Suzhou 215006 P.R. China Suzhou 215006 P.R. China"
            },
            {
                "name": "Wei-mou Zheng",
                "org": "Academia Sinica Beijing Genomics Institute (BGI) Beijing 101300 P.R. China Beijing 101300 P.R. China"
            },
            {
                "name": "Bai-lin Hao",
                "org": "Academia Sinica Institute of Theoretical Physics Beijing 100080 P.R. China Beijing 100080 P.R. China"
            }
        ],
        "venue": "J. Comput. Sci. Technol.",
        "year": 2005
    },
    "V8UOM2uU": {
        "id": "V8UOM2uU",
        "title": "Omics-based profiling of carcinoma of the breast and matched regional lymph node metastasis.",
        "abstract": "Axillary lymph node (ALN) status is currently used as an important clinical indicator of breast cancer prognosis. However, the molecular mechanisms underlying lymph node metastasis are poorly understood and the relationship between ALN metastasis and the primary tumor remains unclear. In an effort to reveal structural changes in the genome and related protein responses that may drive regional metastatic progression we have analyzed matched pairs of primary breast tumors and ALN metastases both at the genomic and proteomic levels using comparative genomic hybridization (CGH) array, quantitative high-resolution 2-D PAGE in combination with MS, and immunohistochemistry (IHC). Array CGH revealed a remarkable similarity in genomic aberration profiles between the matched primary tumors and the ALN metastases. Quantitative profiling of 135 known proteins also revealed striking similarities in their overall expression patterns, although we observed distinct changes in the levels of individual proteins in some sample pairs. The remarkable similarities of the overall genomic and proteomic profiles between primary tumors and matched ALN metastases are taken to suggest that, in general, key biological characteristics of the primary breast tumor are maintained in the corresponding lymph node metastases. Given that the omics-based technologies are oblivious to changes that only occur in minor cellular subsets we validated the proteomic data using IHC, which provides protein expression information with a valuable topological component. Besides confirming the omics-derived data, the IHC analysis revealed that in two cases the ALN metastases may have been derived from a distinct minor cell subpopulation present in the primary tumor rather than from the bulk of it.",
        "keywords": [
            "breast cancer / genomics / immunohistochemistry / primary tumor and lymph node metastases",
            "immunohistochemistry",
            "high resolution",
            "breast cancer",
            "protein expression",
            "genomics",
            "structural change",
            "molecular mechanics"
        ],
        "authors": [
            {
                "name": "Jian Li",
                "org": "Institute of Human Genetics|University of Aarhus"
            },
            {
                "name": "Pavel Gromov",
                "org": "Proteomics in Cancer|Institute of Cancer Biology|Danish Cancer Society|Danish Centre for Translational Breast Cancer Research ( DCTB )"
            },
            {
                "name": "Irina Gromova",
                "org": "Proteomics in Cancer|Institute of Cancer Biology|Danish Cancer Society|Danish Centre for Translational Breast Cancer Research ( DCTB )"
            },
            {
                "name": "Jos\u00e9 M. Moreira",
                "org": "Proteomics in Cancer|Institute of Cancer Biology|Danish Cancer Society|Danish Centre for Translational Breast Cancer Research ( DCTB )"
            },
            {
                "name": "Vera Timmermans-Wielenga",
                "org": "Department of Pathology|Centre of Diagnostic Investigations"
            },
            {
                "name": "Fritz Rank",
                "org": "Department of Pathology|Centre of Diagnostic Investigations"
            },
            {
                "name": "Kai Wang",
                "org": "Institute of Human Genetics|University of Aarhus"
            },
            {
                "name": "Shengting Li",
                "org": "Institute of Human Genetics|University of Aarhus"
            },
            {
                "name": "Heng Li",
                "org": "Institute of Human Genetics|University of Aarhus"
            },
            {
                "name": "Carsten Wiuf",
                "org": "Bioinformatics Research Center|University of Aarhus"
            },
            {
                "name": "Huanming Yang",
                "org": "Beijing Institute of Genomics|Chinese Academy of Sciences"
            },
            {
                "name": "Xiuqing Zhang",
                "org": "Beijing Institute of Genomics|Chinese Academy of Sciences"
            },
            {
                "name": "Lars Bolund",
                "org": "Institute of Human Genetics|University of Aarhus"
            },
            {
                "name": "Julio E. Celis",
                "org": "Proteomics in Cancer|Institute of Cancer Biology|Danish Cancer Society|Danish Centre for Translational Breast Cancer Research ( DCTB )"
            }
        ],
        "venue": "Proteomics",
        "year": 2008
    },
    "uVNVy6GA": {
        "id": "uVNVy6GA",
        "title": "Fast and accurate long-read alignment with Burrows-Wheeler transform.",
        "abstract": "Many programs for aligning short sequencing reads to a reference genome have been developed in the last 2 years. Most of them are very efficient for short reads but inefficient or not applicable for reads >200 bp because the algorithms are heavily and specifically tuned for short queries with low sequencing error rate. However, some sequencing platforms already produce longer reads and others are expected to become available soon. For longer reads, hashing-based software such as BLAT and SSAHA2 remain the only choices. Nonetheless, these methods are substantially slower than short-read aligners in terms of aligned bases per unit time.We designed and implemented a new algorithm, Burrows-Wheeler Aligner's Smith-Waterman Alignment (BWA-SW), to align long sequences up to 1 Mb against a large sequence database (e.g. the human genome) with a few gigabytes of memory. The algorithm is as accurate as SSAHA2, more accurate than BLAT, and is several to tens of times faster than both.http://bio-bwa.sourceforge.net",
        "keywords": [
            "low sequencing error rate",
            "human genome",
            "hashing-based software",
            "accurate long-read alignment",
            "short query",
            "burrows-wheeler aligner",
            "short sequencing",
            "smith-waterman alignment",
            "reference genome",
            "new algorithm",
            "sequencing platform",
            "sequence alignment",
            "dna sequence",
            "hash table",
            "genomics",
            "color space",
            "error rate",
            "algorithms",
            "burrows wheeler transform"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Richard Durbin",
                "org": ""
            }
        ],
        "venue": "Bioinformatics",
        "year": 2010
    },
    "vaGmAteg": {
        "id": "vaGmAteg",
        "title": "TreeFam: 2008 Update.",
        "abstract": "TreeFam (http://www.treefam.org) was developed to provide curated phylogenetic trees for all animal gene families, as well as orthologue and paralogue assignments. Release 4.0 of TreeFam contains curated trees for 1314 families and automatically generated trees for another 14,351 families. We have expanded TreeFam to include 25 fully sequenced animal genomes, as well as four genomes from plant and fungal outgroup species. We have also introduced more accurate approaches for automatically grouping genes into families, for building phylogenetic trees, and for inferring orthologues and paralogues. The user interface for viewing phylogenetic trees and family information has been improved. Furthermore, a new perl API lets users easily extract data from the TreeFam mysql database.",
        "keywords": [
            "phylogeny",
            "genomics",
            "internet"
        ],
        "authors": [
            {
                "name": "Jue Ruan",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Zhongzhong Chen",
                "org": ""
            },
            {
                "name": "Avril Coghlan",
                "org": ""
            },
            {
                "name": "Lachlan James M. Coin",
                "org": ""
            },
            {
                "name": "Yiran Guo",
                "org": ""
            },
            {
                "name": "Jean-karim H\u00e9rich\u00e9",
                "org": ""
            },
            {
                "name": "Yafeng Hu",
                "org": ""
            },
            {
                "name": "Karsten Kristiansen",
                "org": ""
            },
            {
                "name": "Ruiqiang Li",
                "org": ""
            },
            {
                "name": "Tao Liu",
                "org": ""
            },
            {
                "name": "Alan Moses",
                "org": ""
            },
            {
                "name": "Junjie Qin",
                "org": ""
            },
            {
                "name": "S\u00f8ren Vang",
                "org": ""
            },
            {
                "name": "Albert J. Vilella",
                "org": ""
            },
            {
                "name": "Abel Ureta-vidal",
                "org": ""
            },
            {
                "name": "Lars Bolund",
                "org": ""
            },
            {
                "name": "Jun Wang",
                "org": ""
            },
            {
                "name": "Richard Durbin",
                "org": ""
            }
        ],
        "venue": "Nucleic Acids Research",
        "year": 2008
    },
    "UIvOnzE4": {
        "id": "UIvOnzE4",
        "title": "TreeFam: a curated database of phylogenetic trees of animal gene families.",
        "abstract": "TreeFam is a database of phylogenetic trees of gene families found in animals. It aims to develop a curated resource that presents the accurate evolutionary history of all animal gene families, as well as reliable ortholog and paralog assignments. Curated families are being added progressively, based on seed alignments and trees in a similar fashion to Pfam. Release 1.1 of TreeFam contains curated trees for 690 families and automatically generated trees for another 11 646 families. These represent over 128 000 genes from nine fully sequenced animal genomes and over 45 000 other animal proteins from UniProt; approximately 40-85% of proteins encoded in the fully sequenced animal genomes are included in TreeFam. TreeFam is freely available at http://www.treefam.org and http://treefam.genomics.org.cn.",
        "keywords": [
            "paralogs",
            "duplication",
            "phylogenetic tree",
            "proteins",
            "resources",
            "genome",
            "genomics",
            "genes",
            "phylogenomics",
            "protein families",
            "evolution",
            "internet",
            "orthologs",
            "gene family",
            "phylogeny"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Avril Coghlan",
                "org": ""
            },
            {
                "name": "Jue Ruan",
                "org": ""
            },
            {
                "name": "Lachlan James M. Coin",
                "org": ""
            },
            {
                "name": "Jean-karim H\u00e9rich\u00e9",
                "org": ""
            },
            {
                "name": "Lara Osmotherly",
                "org": ""
            },
            {
                "name": "Ruiqiang Li",
                "org": ""
            },
            {
                "name": "Tao Liu",
                "org": ""
            },
            {
                "name": "Zhang Zhang",
                "org": ""
            },
            {
                "name": "Lars Bolund",
                "org": ""
            },
            {
                "name": "Gane Ka-shu Wong",
                "org": ""
            },
            {
                "name": "Wei-mou Zheng",
                "org": ""
            },
            {
                "name": "Paramvir Dehal",
                "org": ""
            },
            {
                "name": "Jun Wang",
                "org": ""
            },
            {
                "name": "Richard Durbin",
                "org": ""
            }
        ],
        "venue": "Nucleic Acids Research",
        "year": 2006
    },
    "CDSi5oJT": {
        "id": "CDSi5oJT",
        "title": "Evolutionary transients in the rice transcriptome.",
        "abstract": "In the canonical version of evolution by gene duplication, one copy is kept unaltered while the other is free to evolve. This process of evolutionary experimentation can persist for millions of years. Since it is so short lived in comparison to the lifetime of the core genes that make up the majority of most genomes, a substantial fraction of the genome and the transcriptome may-in principle-be attributable to what we will refer to as \"evolutionary transients\", referring here to both the process and the genes that have gone or are undergoing this process. Using the rice gene set as a test case, we argue that this phenomenon goes a long way towards explaining why there are so many more rice genes than Arabidopsis genes, and why most excess rice genes show low similarity to eudicots.",
        "keywords": [
            "evolutionary transients",
            "rice",
            "gene duplication"
        ],
        "authors": [
            {
                "name": "Jun Wang",
                "org": ""
            },
            {
                "name": "Jianguo Zhang",
                "org": ""
            },
            {
                "name": "Ruiqiang Li",
                "org": ""
            },
            {
                "name": "Hongkun Zheng",
                "org": ""
            },
            {
                "name": "Jun Li",
                "org": "Beijing Genomics Institute at Shenzhen, Shenzhen 518083, China"
            },
            {
                "name": "Yong Zhang",
                "org": "Beijing Genomics Institute at Shenzhen, Shenzhen 518083, China"
            },
            {
                "name": "Heng Li",
                "org": "Beijing Genomics Institute at Shenzhen, Shenzhen 518083, China"
            },
            {
                "name": "Peixiang Ni",
                "org": "Beijing Genomics Institute at Shenzhen, Shenzhen 518083, China"
            },
            {
                "name": "Songgang Li",
                "org": "Beijing Genomics Institute at Shenzhen, Shenzhen 518083, China"
            },
            {
                "name": "Shengting Li",
                "org": "Beijing Genomics Institute at Shenzhen, Shenzhen 518083, China"
            },
            {
                "name": "Jingqiang Wang",
                "org": "Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100029, China"
            },
            {
                "name": "Dongyuan Liu",
                "org": "Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100029, China"
            },
            {
                "name": "Jason McDermott",
                "org": "Computational Biology and Bioinformatics, Pacific Northwest National Laboratory, Richland, WA 99352, USA"
            },
            {
                "name": "Ram Samudrala",
                "org": "Computational Genomics Group, Department of Microbiology, University of Washington, Seattle, WA 98195, USA"
            },
            {
                "name": "Siqi Liu",
                "org": "Beijing Genomics Institute at Shenzhen, Shenzhen 518083, China"
            },
            {
                "name": "Jian Wang",
                "org": "Beijing Genomics Institute at Shenzhen, Shenzhen 518083, China"
            },
            {
                "name": "Huanming Yang",
                "org": "Beijing Genomics Institute at Shenzhen, Shenzhen 518083, China"
            },
            {
                "name": "Jun Yu",
                "org": ""
            },
            {
                "name": "Gane Ka-Shu Wong",
                "org": ""
            }
        ],
        "venue": "Genomics, Proteomics & Bioinformatics",
        "year": 2010
    },
    "uvkN6oFn": {
        "id": "uvkN6oFn",
        "title": "Porcine transcriptome analysis based on 97 non-normalized cDNA libraries and assembly of 1,021,891 expressed sequence tags.",
        "abstract": "Knowledge of the structure of gene expression is essential for mammalian transcriptomics research. We analyzed a collection of more than one million porcine expressed sequence tags (ESTs), of which two-thirds were generated in the Sino-Danish Pig Genome Project and one-third are from public databases. The Sino-Danish ESTs were generated from one normalized and 97 non-normalized cDNA libraries representing 35 different tissues and three developmental stages.Using the Distiller package, the ESTs were assembled to roughly 48,000 contigs and 73,000 singletons, of which approximately 25% have a high confidence match to UniProt. Approximately 6,000 new porcine gene clusters were identified. Expression analysis based on the non-normalized libraries resulted in the following findings. The distribution of cluster sizes is scaling invariant. Brain and testes are among the tissues with the greatest number of different expressed genes, whereas tissues with more specialized function, such as developing liver, have fewer expressed genes. There are at least 65 high confidence housekeeping gene candidates and 876 cDNA library-specific gene candidates. We identified differential expression of genes between different tissues, in particular brain/spinal cord, and found patterns of correlation between genes that share expression in pairs of libraries. Finally, there was remarkable agreement in expression between specialized tissues according to Gene Ontology categories.This EST collection, the largest to date in pig, represents an essential resource for annotation, comparative genomics, assembly of the pig genome sequence, and further porcine transcription studies.",
        "keywords": [
            "cluster analysis",
            "gene expression",
            "housekeeping gene",
            "expressed sequence tags",
            "gene library",
            "computational biology",
            "special functions",
            "gene cluster",
            "genome sequence",
            "comparative genomics",
            "expressed sequence tag",
            "genomics",
            "cdna library",
            "scale invariance",
            "gene expression profiling"
        ],
        "authors": [
            {
                "name": "Jan Gorodkin",
                "org": "Division of Genetics and Bioinformatics, IBHV, Gr\u00f8nneg\u00e4rdsvej 3, The Royal Veterinary and Agricultural University, DK-1870 Frederiksberg C, Denmark"
            },
            {
                "name": "Susanna Cirera",
                "org": "Division of Genetics and Bioinformatics, IBHV, Gr\u00f8nneg\u00e4rdsvej 3, The Royal Veterinary and Agricultural University, DK-1870 Frederiksberg C, Denmark"
            },
            {
                "name": "Jakob Hedegaard",
                "org": "Department of Genetics and Biotechnology, Danish Institute of Agricultural Sciences, Blichers Alle, DK-8830 Tjele, Denmark"
            },
            {
                "name": "Michael J Gilchrist",
                "org": "The Wellcome Trust/Cancer Research UK Gurdon Institute, Cambridge, CB2 1QN, UK"
            },
            {
                "name": "Frank Panitz",
                "org": "Department of Genetics and Biotechnology, Danish Institute of Agricultural Sciences, Blichers Alle, DK-8830 Tjele, Denmark"
            },
            {
                "name": "Claus J\u00f8rgensen",
                "org": "Division of Genetics and Bioinformatics, IBHV, Gr\u00f8nneg\u00e4rdsvej 3, The Royal Veterinary and Agricultural University, DK-1870 Frederiksberg C, Denmark"
            },
            {
                "name": "Karsten Scheibye-Knudsen",
                "org": "Division of Genetics and Bioinformatics, IBHV, Gr\u00f8nneg\u00e4rdsvej 3, The Royal Veterinary and Agricultural University, DK-1870 Frederiksberg C, Denmark"
            },
            {
                "name": "Troels Arvin",
                "org": "Division of Genetics and Bioinformatics, IBHV, Gr\u00f8nneg\u00e4rdsvej 3, The Royal Veterinary and Agricultural University, DK-1870 Frederiksberg C, Denmark"
            },
            {
                "name": "Steen Lumholdt",
                "org": "Division of Genetics and Bioinformatics, IBHV, Gr\u00f8nneg\u00e4rdsvej 3, The Royal Veterinary and Agricultural University, DK-1870 Frederiksberg C, Denmark"
            },
            {
                "name": "Milena Sawera",
                "org": "Division of Genetics and Bioinformatics, IBHV, Gr\u00f8nneg\u00e4rdsvej 3, The Royal Veterinary and Agricultural University, DK-1870 Frederiksberg C, Denmark"
            },
            {
                "name": "Trine Green",
                "org": "Division of Genetics and Bioinformatics, IBHV, Gr\u00f8nneg\u00e4rdsvej 3, The Royal Veterinary and Agricultural University, DK-1870 Frederiksberg C, Denmark"
            },
            {
                "name": "Bente J Nielsen",
                "org": "Division of Genetics and Bioinformatics, IBHV, Gr\u00f8nneg\u00e4rdsvej 3, The Royal Veterinary and Agricultural University, DK-1870 Frederiksberg C, Denmark"
            },
            {
                "name": "Jakob H Havgaard",
                "org": "Division of Genetics and Bioinformatics, IBHV, Gr\u00f8nneg\u00e4rdsvej 3, The Royal Veterinary and Agricultural University, DK-1870 Frederiksberg C, Denmark"
            },
            {
                "name": "Carina Rosenkilde",
                "org": "Division of Genetics and Bioinformatics, IBHV, Gr\u00f8nneg\u00e4rdsvej 3, The Royal Veterinary and Agricultural University, DK-1870 Frederiksberg C, Denmark"
            },
            {
                "name": "Jun Wang",
                "org": "Beijing Genomics Institute, The Airport Industrial Road, Beijing 101300, PR China|Institute of Human Genetics, University of Aarhus, Nordre Ringgade 1, DK-8000 Aarhus C, Denmark|Department of Biochemistry and Molecular Biology, University of Southern Denmark, Campus Vej 55, DK-5230 Odense M, Denmark"
            },
            {
                "name": "Heng Li",
                "org": "Beijing Genomics Institute, The Airport Industrial Road, Beijing 101300, PR China|Institute of Human Genetics, University of Aarhus, Nordre Ringgade 1, DK-8000 Aarhus C, Denmark"
            },
            {
                "name": "Ruiqiang Li",
                "org": "Beijing Genomics Institute, The Airport Industrial Road, Beijing 101300, PR China|Department of Biochemistry and Molecular Biology, University of Southern Denmark, Campus Vej 55, DK-5230 Odense M, Denmark"
            },
            {
                "name": "Bin Liu",
                "org": "Beijing Genomics Institute, The Airport Industrial Road, Beijing 101300, PR China"
            },
            {
                "name": "Songnian Hu",
                "org": "Beijing Genomics Institute, The Airport Industrial Road, Beijing 101300, PR China"
            },
            {
                "name": "Wei Dong",
                "org": "Beijing Genomics Institute, The Airport Industrial Road, Beijing 101300, PR China"
            },
            {
                "name": "Wei Li",
                "org": "Beijing Genomics Institute, The Airport Industrial Road, Beijing 101300, PR China"
            },
            {
                "name": "Jun Yu",
                "org": "Beijing Genomics Institute, The Airport Industrial Road, Beijing 101300, PR China"
            },
            {
                "name": "Jian Wang",
                "org": "Beijing Genomics Institute, The Airport Industrial Road, Beijing 101300, PR China"
            },
            {
                "name": "Hans-Henrik St\u00e6rfeldt",
                "org": "Center for Biological Sequence Analysis, BioCentrum-DTU, Building 208, DK-2800 Lyngby, Denmark"
            },
            {
                "name": "Rasmus Wernersson",
                "org": "Center for Biological Sequence Analysis, BioCentrum-DTU, Building 208, DK-2800 Lyngby, Denmark"
            },
            {
                "name": "Lone B Madsen",
                "org": "Department of Genetics and Biotechnology, Danish Institute of Agricultural Sciences, Blichers Alle, DK-8830 Tjele, Denmark"
            },
            {
                "name": "Bo Thomsen",
                "org": "Department of Genetics and Biotechnology, Danish Institute of Agricultural Sciences, Blichers Alle, DK-8830 Tjele, Denmark"
            },
            {
                "name": "Henrik Hornsh\u00f8j",
                "org": "Department of Genetics and Biotechnology, Danish Institute of Agricultural Sciences, Blichers Alle, DK-8830 Tjele, Denmark"
            },
            {
                "name": "Zhan Bujie",
                "org": "Department of Genetics and Biotechnology, Danish Institute of Agricultural Sciences, Blichers Alle, DK-8830 Tjele, Denmark"
            },
            {
                "name": "Xuegang Wang",
                "org": "Department of Genetics and Biotechnology, Danish Institute of Agricultural Sciences, Blichers Alle, DK-8830 Tjele, Denmark"
            },
            {
                "name": "Xuefei Wang",
                "org": "Department of Genetics and Biotechnology, Danish Institute of Agricultural Sciences, Blichers Alle, DK-8830 Tjele, Denmark"
            },
            {
                "name": "Lars Bolund",
                "org": "Beijing Genomics Institute, The Airport Industrial Road, Beijing 101300, PR China|Institute of Human Genetics, University of Aarhus, Nordre Ringgade 1, DK-8000 Aarhus C, Denmark"
            },
            {
                "name": "S\u00f8ren Brunak",
                "org": "Center for Biological Sequence Analysis, BioCentrum-DTU, Building 208, DK-2800 Lyngby, Denmark"
            },
            {
                "name": "Huanming Yang",
                "org": "Beijing Genomics Institute, The Airport Industrial Road, Beijing 101300, PR China"
            },
            {
                "name": "Christian Bendixen",
                "org": "Department of Genetics and Biotechnology, Danish Institute of Agricultural Sciences, Blichers Alle, DK-8830 Tjele, Denmark"
            },
            {
                "name": "Merete Fredholm",
                "org": "Division of Genetics and Bioinformatics, IBHV, Gr\u00f8nneg\u00e4rdsvej 3, The Royal Veterinary and Agricultural University, DK-1870 Frederiksberg C, Denmark"
            }
        ],
        "venue": "Genome biology",
        "year": 2007
    },
    "ESr5d1Fu": {
        "id": "ESr5d1Fu",
        "title": "Genes controlling seed dormancy and pre-harvest sprouting in a rice-wheat-barley comparison.",
        "abstract": "Pre-harvest sprouting results in significant economic loss for the grain industry around the world. Lack of adequate seed dormancy is the major reason for pre-harvest sprouting in the field under wet weather conditions. Although this trait is governed by multiple genes it is also highly heritable. A major QTL controlling both pre-harvest sprouting and seed dormancy has been identified on the long arm of barley chromosome 5H, and it explains over 70% of the phenotypic variation. Comparative genomics approaches among barley, wheat and rice were used to identify candidate gene(s) controlling seed dormancy and hence one aspect of pre-harvest sprouting. The barley seed dormancy/pre-harvest sprouting QTL was located in a region that showed good synteny with the terminal end of the long arm of rice chromosome 3. The rice DNA sequences were annotated and a gene encoding GA20-oxidase was identified as a candidate gene controlling the seed dormancy/pre-harvest sprouting QTL on 5HL. This chromosomal region also shared synteny with the telomere region of wheat chromosome 4AL, but was located outside of the QTL reported for seed dormancy in wheat. The wheat chromosome 4AL QTL region for seed dormancy was syntenic to both rice chromosome 3 and 11. In both cases, corresponding QTLs for seed dormancy have been mapped in rice.",
        "keywords": [
            "Seed dormancy",
            "Pre-harvest sprouting",
            "Comparative mapping",
            "Candidate gene",
            "Rice genome sequences"
        ],
        "authors": [
            {
                "name": "Chengdao Li",
                "org": "Department of Agriculture 3 Baron-Hay Court WA 6151 South Perth Australia"
            },
            {
                "name": "Peixiang Ni",
                "org": "Beijing Institute of Genomics Chinese Academy of Sciences 101300 Beijing China"
            },
            {
                "name": "Michael Francki",
                "org": "Department of Agriculture 3 Baron-Hay Court WA 6151 South Perth Australia"
            },
            {
                "name": "Adam Hunter",
                "org": "Centre of Bioinformatics and Biological Computing Murdoch University WA 6150 Murdoch Australia"
            },
            {
                "name": "Yong Zhang",
                "org": "Beijing Institute of Genomics Chinese Academy of Sciences 101300 Beijing China"
            },
            {
                "name": "David Schibeci",
                "org": "Centre of Bioinformatics and Biological Computing Murdoch University WA 6150 Murdoch Australia"
            },
            {
                "name": "Heng Li",
                "org": "Beijing Institute of Genomics Chinese Academy of Sciences 101300 Beijing China"
            },
            {
                "name": "Allen Tarr",
                "org": "Department of Agriculture 3 Baron-Hay Court WA 6151 South Perth Australia"
            },
            {
                "name": "Jun Wang",
                "org": "Beijing Institute of Genomics Chinese Academy of Sciences 101300 Beijing China"
            },
            {
                "name": "Mehmet Cakir",
                "org": "Molecular Plant Breeding CRC-Western Node, SABC Murdoch University WA 6150 Murdoch Australia"
            },
            {
                "name": "Jun Yu",
                "org": "Beijing Institute of Genomics Chinese Academy of Sciences 101300 Beijing China"
            },
            {
                "name": "Matthew Bellgard",
                "org": "Centre of Bioinformatics and Biological Computing Murdoch University WA 6150 Murdoch Australia"
            },
            {
                "name": "Reg Lance",
                "org": "Department of Agriculture 3 Baron-Hay Court WA 6151 South Perth Australia"
            },
            {
                "name": "Rudi Appels",
                "org": "Department of Agriculture 3 Baron-Hay Court WA 6151 South Perth Australia"
            }
        ],
        "venue": "Functional & integrative genomics",
        "year": 2004
    },
    "X80ysOA1": {
        "id": "X80ysOA1",
        "title": "Fast and accurate short read alignment with Burrows-Wheeler transform.",
        "abstract": "The enormous amount of short reads generated by the new DNA sequencing technologies call for the development of fast and accurate read alignment programs. A first generation of hash table-based methods has been developed, including MAQ, which is accurate, feature rich and fast enough to align short reads from a single individual. However, MAQ does not support gapped alignment for single-end reads, which makes it unsuitable for alignment of longer reads where indels may occur frequently. The speed of MAQ is also a concern when the alignment is scaled up to the resequencing of hundreds of individuals.We implemented Burrows-Wheeler Alignment tool (BWA), a new read alignment package that is based on backward search with Burrows-Wheeler Transform (BWT), to efficiently align short sequencing reads against a large reference sequence such as the human genome, allowing mismatches and gaps. BWA supports both base space reads, e.g. from Illumina sequencing machines, and color space reads from AB SOLiD machines. Evaluations on both simulated and real data suggest that BWA is approximately 10-20x faster than MAQ, while achieving similar accuracy. In addition, BWA outputs alignment in the new standard SAM (Sequence Alignment/Map) format. Variant calling and other downstream analyses after the alignment can be achieved with the open source SAMtools software package.http://maq.sourceforge.net.",
        "keywords": [
            "new standard sam",
            "sequence alignment",
            "gapped alignment",
            "new read alignment package",
            "accurate short read alignment",
            "illumina sequencing machine",
            "burrows-wheeler alignment tool",
            "new dna",
            "accurate read alignment program",
            "bwa outputs alignment",
            "align short sequencing"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Richard Durbin",
                "org": ""
            }
        ],
        "venue": "Bioinformatics",
        "year": 2009
    },
    "yy7lllwC": {
        "id": "yy7lllwC",
        "title": "Mouse transcriptome:  Neutral evolution of \u2018non-coding\u2019 complementary DNAs (reply)",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Yoshihide Hyashizaki",
                "org": ""
            },
            {
                "name": "Jianguo Zhang",
                "org": ""
            },
            {
                "name": "Hongkun Zheng",
                "org": ""
            },
            {
                "name": "Jun Li",
                "org": ""
            },
            {
                "name": "Dongyuan Liu",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Ram Samudrala",
                "org": ""
            },
            {
                "name": "Jun Yu",
                "org": ""
            },
            {
                "name": "Gane Ka-Shu Wong",
                "org": ""
            }
        ],
        "venue": "Nature",
        "year": 2004
    },
    "ZVffJ5Tg": {
        "id": "ZVffJ5Tg",
        "title": "A cross-species alignment tool (CAT).",
        "abstract": "The main two sorts of automatic gene annotation frameworks are ab initio and alignment-based, the latter splitting into two sub-groups. The first group is used for intra-species alignments, among which are successful ones with high specificity and speed. The other group contains more sensitive methods which are usually applied in aligning inter-species sequences.Here we present a new algorithm called CAT (for Cross-species Alignment Tool). It is designed to align mRNA sequences to mammalian-sized genomes. CAT is implemented using C scripts and is freely available on the web at http://xat.sourceforge.net/.Examined from different angles, CAT outperforms other extant alignment tools. Tested against all available mouse-human and zebrafish-human orthologs, we demonstrate that CAT combines the specificity and speed of the best intra-species algorithms, like BLAT and sim4, with the sensitivity of the best inter-species tools, like GeneWise.",
        "keywords": [
            "microarrays",
            "bioinformatics",
            "sequence alignment",
            "algorithms"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": "Beijing Institute of Genomics of Chinese Academy of Sciences, Beijing Genomics Institute, Beijing 101300, China|James D. Watson Institute of Genome Sciences of Zhejiang University, Hangzhou 310008, China|Institute of Theoretical Physics, Chinese Academy of Sciences, Beijing 100080, China|Graduate University of the Chinese Academy of Sciences, Yuquan Road 19A, Beijing 100039, China"
            },
            {
                "name": "Liang Guan",
                "org": "Beijing Institute of Genomics of Chinese Academy of Sciences, Beijing Genomics Institute, Beijing 101300, China|James D. Watson Institute of Genome Sciences of Zhejiang University, Hangzhou 310008, China|Graduate University of the Chinese Academy of Sciences, Yuquan Road 19A, Beijing 100039, China|Institute of Computing Technology, Chinese Academy of Science, Beijing 100080, China"
            },
            {
                "name": "Tao Liu",
                "org": "Beijing Institute of Genomics of Chinese Academy of Sciences, Beijing Genomics Institute, Beijing 101300, China|James D. Watson Institute of Genome Sciences of Zhejiang University, Hangzhou 310008, China"
            },
            {
                "name": "Yiran Guo",
                "org": "Beijing Institute of Genomics of Chinese Academy of Sciences, Beijing Genomics Institute, Beijing 101300, China|Graduate University of the Chinese Academy of Sciences, Yuquan Road 19A, Beijing 100039, China"
            },
            {
                "name": "Wei-mou Zheng",
                "org": "Beijing Institute of Genomics of Chinese Academy of Sciences, Beijing Genomics Institute, Beijing 101300, China|James D. Watson Institute of Genome Sciences of Zhejiang University, Hangzhou 310008, China|Institute of Theoretical Physics, Chinese Academy of Sciences, Beijing 100080, China"
            },
            {
                "name": "Gane Ka-shu Wong",
                "org": "Beijing Institute of Genomics of Chinese Academy of Sciences, Beijing Genomics Institute, Beijing 101300, China|James D. Watson Institute of Genome Sciences of Zhejiang University, Hangzhou 310008, China|UW Genome Center, Department of Medicine, University of Washington, Seattle, WA 98195, USA"
            },
            {
                "name": "Jun Wang",
                "org": "Beijing Institute of Genomics of Chinese Academy of Sciences, Beijing Genomics Institute, Beijing 101300, China|James D. Watson Institute of Genome Sciences of Zhejiang University, Hangzhou 310008, China|The Institute of Human Genetics, University of Aarhus, DK-8000 Aarhus C, Denmark|Department of Biochemistry and Molecular Biology, University of Southern Denmark, DK-5230, Odense M, Denmark"
            }
        ],
        "venue": "BMC Bioinformatics",
        "year": 2007
    },
    "jTKUb90U": {
        "id": "jTKUb90U",
        "title": "pIRS",
        "abstract": "Motivation: The next-generation high-throughput sequencing technologies, especially from Illumina, have been widely used in re-sequencing and de novo assembly studies. However, there is no existing software that can simulate Illumina reads with real error and quality distributions and coverage bias yet, which is very useful in relevant software development and study designing of sequencing projects. Results: We provide a software package, pIRS (profile-based Illumina pair-end reads simulator), which simulates Illumina reads with empirical Base-Calling and GC%-depth profiles trained from real re-sequencing data. The error and quality distributions as well as coverage bias patterns of simulated reads using pIRS fit the properties of real sequencing data better than existing simulators. In addition, pIRS also comes with a tool to simulate the heterozygous diploid genomes. Availability: pIRS is written in C++ and Perl, and is freely available at ftp://ftp.genomics.org.cn/pub/pIRS/. Contact: fanweisz09@gmail.com Supplementary information:Supplementary data are available at Bioinformatics online.",
        "keywords": [
            "real re-sequencing data",
            "sequencing project",
            "profile-based Illumina pair-end",
            "software package",
            "supplementary data",
            "real sequencing data",
            "relevant software development",
            "existing software",
            "quality distribution",
            "real error"
        ],
        "authors": [
            {
                "name": "Xuesong Hu",
                "org": ""
            },
            {
                "name": "Jianying Yuan",
                "org": ""
            },
            {
                "name": "Yujian Shi",
                "org": ""
            },
            {
                "name": "Jianliang Lu",
                "org": ""
            },
            {
                "name": "Binghang Liu",
                "org": ""
            },
            {
                "name": "Zhenyu Li",
                "org": ""
            },
            {
                "name": "Yanxiang Chen",
                "org": ""
            },
            {
                "name": "Desheng Mu",
                "org": ""
            },
            {
                "name": "Hao Zhang",
                "org": ""
            },
            {
                "name": "Nan Li",
                "org": ""
            },
            {
                "name": "Zhen Yue",
                "org": ""
            },
            {
                "name": "Fan Bai",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Wei Fan",
                "org": ""
            }
        ],
        "venue": "Bioinformatics",
        "year": 2012
    },
    "q1JaOGrg": {
        "id": "q1JaOGrg",
        "title": "Deep short-read sequencing of chromosome 17 from the mouse strains A/J and CAST/Ei identifies significant germline variation and candidate genes that regulate liver triglyceride levels.",
        "abstract": "Genome sequences are essential tools for comparative and mutational analyses. Here we present the short read sequence of mouse chromosome 17 from the Mus musculus domesticus derived strain A/J, and the Mus musculus castaneus derived strain CAST/Ei. We describe approaches for the accurate identification of nucleotide and structural variation in the genomes of vertebrate experimental organisms, and show how these techniques can be applied to help prioritize candidate genes within quantitative trait loci.",
        "keywords": [
            "nucleotides",
            "genome sequence",
            "germ line mutation",
            "genome",
            "quality control",
            "candidate gene",
            "major histocompatibility complex",
            "quantitative trait loci",
            "gene dosage"
        ],
        "authors": [
            {
                "name": "Ian Sudbery",
                "org": "The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1HH, UK"
            },
            {
                "name": "Jim Stalker",
                "org": "The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1HH, UK"
            },
            {
                "name": "Jared T Simpson",
                "org": "The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1HH, UK"
            },
            {
                "name": "Thomas Keane",
                "org": "The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1HH, UK"
            },
            {
                "name": "Alistair G Rust",
                "org": "The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1HH, UK"
            },
            {
                "name": "Matthew E Hurles",
                "org": "The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1HH, UK"
            },
            {
                "name": "Klaudia Walter",
                "org": "The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1HH, UK"
            },
            {
                "name": "Dee Lynch",
                "org": "Mammalian Genetics Unit, MRC-Harwell, Harwell Science and Innovation Campus, Oxfordshire, OX11 ORD, UK"
            },
            {
                "name": "Lydia Teboul",
                "org": "Mammalian Genetics Unit, MRC-Harwell, Harwell Science and Innovation Campus, Oxfordshire, OX11 ORD, UK"
            },
            {
                "name": "Steve D Brown",
                "org": "Mammalian Genetics Unit, MRC-Harwell, Harwell Science and Innovation Campus, Oxfordshire, OX11 ORD, UK"
            },
            {
                "name": "Heng Li",
                "org": "The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1HH, UK"
            },
            {
                "name": "Zemin Ning",
                "org": "The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1HH, UK"
            },
            {
                "name": "Joseph H Nadeau",
                "org": "Department of Genetics, Case Western Reserve University, Adelbert Rd, Cleveland, OH 44106-4955. USA"
            },
            {
                "name": "Colleen M Croniger",
                "org": "Department of Genetics, Case Western Reserve University, Adelbert Rd, Cleveland, OH 44106-4955. USA"
            },
            {
                "name": "Richard Durbin",
                "org": "The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1HH, UK"
            },
            {
                "name": "David J Adams",
                "org": "The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1HH, UK"
            }
        ],
        "venue": "Genome biology",
        "year": 2009
    },
    "0U2FtQZw": {
        "id": "0U2FtQZw",
        "title": "A Bayesian deconvolution strategy for immunoprecipitation-based DNA methylome analysis",
        "abstract": "DNA methylation is an indispensible epigenetic modification required for regulating the expression of mammalian genomes. Immunoprecipitation-based methods for DNA methylome analysis are rapidly shifting the bottleneck in this field from data generation to data analysis, necessitating the development of better analytical tools. In particular, an in- ability to estimate absolute methylation levels remains a major analytical difficulty associated with immunoprecipitation- based DNA methylation profiling. To address this issue, we developed a cross-platform algorithm\u2014Bayesian tool for methylation analysis (Batman)\u2014for analyzing methylated DNA immunoprecipitation (MeDIP) profiles generated using oligonucleotide arrays (MeDIP-chip) or next-generation sequencing (MeDIP-seq). We developed the latter approach to provide a high-resolution whole-genome DNA methylation profile (DNA methylome) of a mammalian genome. Strong correlation of our data, obtained using mature human spermatozoa, with those obtained using bisulfite sequencing suggest that combining MeDIP-seq or MeDIP-chip with Batman provides a robust, quantitative and cost-effective functional genomic strategy for elucidating the function of DNA methylation. Modulation of the epigenome\u2014the combination of DNA- and chromatin-associated epigenetic modifications that exist within a cell\u2014is one of the key mechanisms by which cells generate functional diversity from an essentially static genome1. The epigenome is a",
        "keywords": [
            "high resolution",
            "algorithms",
            "microarray",
            "genes",
            "cost effectiveness",
            "bayes theorem",
            "next generation sequencing",
            "epigenome",
            "cancer cells",
            "functional genomics",
            "chromatin immunoprecipitation",
            "dna methylation",
            "genomic dna",
            "dna",
            "chip",
            "data analysis"
        ],
        "authors": [
            {
                "name": "Thomas A Down",
                "org": "Wellcome Trust Cancer Research UK|Department of Genetics|University of Cambridge"
            },
            {
                "name": "Vardhman K Rakyan",
                "org": "Institute of Cell and Molecular Science"
            },
            {
                "name": "Daniel J Turner",
                "org": ""
            },
            {
                "name": "Paul Flicek",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Eugene Kulesha",
                "org": ""
            },
            {
                "name": "Stefan Gr\u00e4f",
                "org": ""
            },
            {
                "name": "Nathan Johnson",
                "org": ""
            },
            {
                "name": "Javier Herrero",
                "org": ""
            },
            {
                "name": "Eleni M Tomazou",
                "org": ""
            },
            {
                "name": "Natalie P Thorne",
                "org": "Department of Oncology|University of Cambridge|Cancer Research UK|Cambridge Research Institute|Li Ka Shing Centre"
            },
            {
                "name": "Liselotte B\u00e4ckdahl",
                "org": "University College London"
            },
            {
                "name": "Marlis Herberth",
                "org": "Institute of Biotechnology|University of Cambridge"
            },
            {
                "name": "Kevin L Howe",
                "org": "Department of Oncology|University of Cambridge|Cancer Research UK|Cambridge Research Institute|Li Ka Shing Centre"
            },
            {
                "name": "David K Jackson",
                "org": ""
            },
            {
                "name": "Marcos M Miretti",
                "org": ""
            },
            {
                "name": "John C Marioni",
                "org": "Department of Oncology|University of Cambridge|Cancer Research UK|Cambridge Research Institute|Li Ka Shing Centre"
            },
            {
                "name": "Ewan Birney",
                "org": ""
            },
            {
                "name": "Tim J P Hubbard",
                "org": ""
            },
            {
                "name": "Richard Durbin",
                "org": ""
            },
            {
                "name": "Simon Tavar\u00e9",
                "org": ""
            },
            {
                "name": "Stephan Beck",
                "org": "University College London"
            }
        ],
        "venue": "Nature Biotechnology",
        "year": 2008
    },
    "zWWyu3PH": {
        "id": "zWWyu3PH",
        "title": "PigGIS: Pig Genomic Informatics System.",
        "abstract": "Pig Genomic Information System (PigGIS) is a web-based depository of pig (Sus scrofa) genomic learning mainly engineered for biomedical research to locate pig genes from their human homologs and position single nucleotide polymorphisms (SNPs) in different pig populations. It utilizes a variety of sequence data, including whole genome shotgun (WGS) reads and expressed sequence tags (ESTs), and achieves a successful mapping solution to the low-coverage genome problem. With the data presently available, we have identified a total of 15 700 pig consensus sequences covering 18.5 Mb of the homologous human exons. We have also recovered 18 700 SNPs and 20 800 unique 60mer oligonucleotide probes for future pig genome analyses. PigGIS can be freely accessed via the web at http://www.piggis.org/ and http://pig.genomics.org.cn/.",
        "keywords": [
            "expressed sequence tags",
            "single nucleotide polymorphism",
            "consensus sequence",
            "sequence alignment",
            "whole genome shotgun",
            "genomics",
            "information system",
            "internet",
            "expressed sequence tag"
        ],
        "authors": [
            {
                "name": "Jue Ruan",
                "org": ""
            },
            {
                "name": "Yiran Guo",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Yafeng Hu",
                "org": ""
            },
            {
                "name": "Fei Song",
                "org": ""
            },
            {
                "name": "Xin Huang",
                "org": ""
            },
            {
                "name": "Karsten Kristiansen",
                "org": ""
            },
            {
                "name": "Lars Bolund",
                "org": ""
            },
            {
                "name": "Jun Wang",
                "org": ""
            }
        ],
        "venue": "Nucleic Acids Research",
        "year": 2007
    },
    "3egvtrME": {
        "id": "3egvtrME",
        "title": "Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing",
        "abstract": "Human cancers often carry many somatically acquired genomic rearrangements, some of which may be implicated in cancer development. However, conventional strategies for characterizing rearrangements are laborious and low-throughput and have low sensitivity or poor resolution. We used massively parallel sequencing to generate sequence reads from both ends of short DNA fragments derived from the genomes of two individuals with lung cancer. By investigating read pairs that did not align correctly with respect to each other on the reference human genome, we characterized 306 germline structural variants and 103 somatic rearrangements to the base-pair level of resolution. The patterns of germline and somatic rearrangement were markedly different. Many somatic rearrangements were from amplicons, although rearrangements outside these regions, notably including tandem duplications, were also observed. Some somatic rearrangements led to abnormal transcripts, including two from internal tandem duplications and two fusion transcripts created by interchromosomal rearrangements. Germline variants were predominantly mediated by retrotransposition, often involving AluY and LINE elements. The results demonstrate the feasibility of systematic, genome-wide characterization of rearrangements in complex human cancer genomes, raising the prospect of a new harvest of genes associated with cancer using this strategy.",
        "keywords": [],
        "authors": [
            {
                "name": "Peter J Campbell",
                "org": ""
            },
            {
                "name": "Philip J Stephens",
                "org": ""
            },
            {
                "name": "Erin D Pleasance",
                "org": ""
            },
            {
                "name": "Sarah O'Meara",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Thomas Santarius",
                "org": ""
            },
            {
                "name": "Lucy A Stebbings",
                "org": ""
            },
            {
                "name": "Catherine Leroy",
                "org": ""
            },
            {
                "name": "Sarah Edkins",
                "org": ""
            },
            {
                "name": "Claire Hardy",
                "org": ""
            },
            {
                "name": "Jon W Teague",
                "org": ""
            },
            {
                "name": "Andrew Menzies",
                "org": ""
            },
            {
                "name": "Ian Goodhead",
                "org": ""
            },
            {
                "name": "Daniel J Turner",
                "org": ""
            },
            {
                "name": "Christopher M Clee",
                "org": ""
            },
            {
                "name": "Michael A Quail",
                "org": ""
            },
            {
                "name": "Antony Cox",
                "org": ""
            },
            {
                "name": "Clive Brown",
                "org": ""
            },
            {
                "name": "Richard Durbin",
                "org": ""
            },
            {
                "name": "Matthew E Hurles",
                "org": ""
            },
            {
                "name": "Paul A W Edwards",
                "org": ""
            },
            {
                "name": "Graham R Bignell",
                "org": ""
            },
            {
                "name": "Michael R Stratton",
                "org": ""
            },
            {
                "name": "P Andrew Futreal",
                "org": ""
            }
        ],
        "venue": "Nature Genetics",
        "year": 2008
    },
    "pOksZ6iy": {
        "id": "pOksZ6iy",
        "title": "Haplotype frequencies in a sub-region of chromosome 19q13.3, related to risk and prognosis of cancer, differ dramatically between ethnic groups",
        "abstract": "BACKGROUND: A small region of about 70 kb on human chromosome 19q13.3 encompasses 4 genes of which 3, ERCC1, ERCC2, and PPP1R13L (aka RAI) are related to DNA repair and cell survival, and one, CD3EAP, aka ASE1, may be related to cell proliferation. The whole region seems related to the cellular response to external damaging agents and markers in it are associated with risk of several cancers. METHODS: We downloaded the genotypes of all markers typed in the 19q13.3 region in the HapMap populations of European, Asian and African descent and inferred haplotypes. We combined the European HapMap individuals with a Danish breast cancer case-control data set and inferred the association between HapMap haplotypes and disease risk. RESULTS: We found that the susceptibility haplotype in our European sample had increased from 2 to 50 percent very recently in the European population, and to almost the same extent in the Asian population. The cause of this increase is unknown. The maximal proportion of overall genetic variation due to differences between groups for Europeans versus Africans and Europeans versus Asians (the Fst value) closely matched the putative location of the susceptibility variant as judged from haplotype-based association mapping. CONCLUSION: The combined observation that a common haplotype causing an increased risk of cancer in Europeans and a high differentiation between human populations is highly unusual and suggests a causal relationship with a recent increase in Europeans caused either by genetic drift overruling selection against the susceptibility variant or a positive selection for the same haplotype. The data does not allow us to distinguish between these two scenarios. The analysis suggests that the region is not involved in cancer risk in Africans and that the susceptibility variants may be more finely mapped in Asian populations.",
        "keywords": [
            "genetic drift",
            "genetic markers",
            "risk factors",
            "ethnic group",
            "cell proliferation",
            "dna repair",
            "human genetics",
            "case control studies",
            "genetic variation",
            "association mapping",
            "breast cancer",
            "gene frequency",
            "haplotypes",
            "molecular epidemiology",
            "positive selection"
        ],
        "authors": [
            {
                "name": "Mikkel H Schierup",
                "org": "Bioinformatics Research Center, University of Aarhus, DK-8000 Aarhus C, Denmark|Genetics and Ecology, Institute of Biology, University of Aarhus, DK-8000 Aarhus C, Denmark"
            },
            {
                "name": "Thomas Mailund",
                "org": "Bioinformatics Research Center, University of Aarhus, DK-8000 Aarhus C, Denmark"
            },
            {
                "name": "Heng Li",
                "org": "Institute of Human Genetics, University of Aarhus, DK-8000 Aarhus C, Denmark|Beijing Genomics Institute at Shenzhen, Shenzhen, PR China"
            },
            {
                "name": "Jun Wang",
                "org": "Beijing Genomics Institute at Shenzhen, Shenzhen, PR China|Department of Biochemistry and Molecular Biology, University of Southern Denmark, DK-5000 Odense, Denmark"
            },
            {
                "name": "Anne Tj\u00f8nneland",
                "org": "Institute for Epidemiological Cancer research, The Danish Cancer Society, DK-2100 Copenhagen O, Denmark"
            },
            {
                "name": "Ulla Vogel",
                "org": "National Food Institute, Technical University of Denmark, DK-2860 S\u00f8borg, Denmark|Institute for Science, Systems and Models, University of Roskilde, DK-4000 Roskilde, Denmark"
            },
            {
                "name": "Lars Bolund",
                "org": "Institute of Human Genetics, University of Aarhus, DK-8000 Aarhus C, Denmark|Beijing Genomics Institute at Shenzhen, Shenzhen, PR China"
            },
            {
                "name": "Bj\u00f8rn A Nex\u00f8",
                "org": "Institute of Human Genetics, University of Aarhus, DK-8000 Aarhus C, Denmark"
            }
        ],
        "venue": "BMC Medical Genetics",
        "year": 2009
    },
    "Jw5Y6TNF": {
        "id": "Jw5Y6TNF",
        "title": "Mapping short DNA sequencing reads and calling variants using mapping quality scores.",
        "abstract": "New sequencing technologies promise a new era in the use of DNA sequence. However, some of these technologies produce very short reads, typically of a few tens of base pairs, and to use these reads effectively requires new algorithms and software. In particular, there is a major issue in efficiently aligning short reads to a reference genome and handling ambiguity or lack of accuracy in this alignment. Here we introduce the concept of mapping quality, a measure of the confidence that a read actually comes from the position it is aligned to by the mapping algorithm. We describe the software MAQ that can build assemblies by mapping shotgun short reads to a reference genome, using quality scores to derive genotype calls of the consensus sequence of a diploid genome, e.g., from a human sample. MAQ makes full use of mate-pair information and estimates the error probability of each read alignment. Error probabilities are also derived for the final genotype calls, using a Bayesian statistical model that incorporates the mapping qualities, error probabilities from the raw sequence quality scores, sampling of the two haplotypes, and an empirical model for correlated errors at a site. Both read mapping and genotype calling are evaluated on simulated data and real data. MAQ is accurate, efficient, versatile, and user-friendly. It is freely available at http://maq.sourceforge.net.",
        "keywords": [
            "alignment",
            "snp detection",
            "algorithms",
            "bayesian statistics",
            "dna",
            "base pair",
            "dna sequence",
            "sequence alignment",
            "bayes theorem",
            "diploidy",
            "error probability",
            "computer simulation",
            "empirical model"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": "Wellcome Trust Sanger Institute|Beijing Genomics Institute|Chinese Academy of Science"
            },
            {
                "name": "Jue Ruan",
                "org": "Beijing Genomics Institute|Chinese Academy of Science"
            },
            {
                "name": "Richard Durbin",
                "org": "Wellcome Trust Sanger Institute|Beijing Genomics Institute|Chinese Academy of Science"
            }
        ],
        "venue": "Genome research",
        "year": 2008
    },
    "wt1homIj": {
        "id": "wt1homIj",
        "title": "Snap: an integrated SNP annotation platform.",
        "abstract": "Snap (Single Nucleotide Polymorphism Annotation Platform) is a server designed to comprehensively analyze single genes and relationships between genes basing on SNPs in the human genome. The aim of the platform is to facilitate the study of SNP finding and analysis within the framework of medical research. Using a user-friendly web interface, genes can be searched by name, description, position, SNP ID or clone name. Several public databases are integrated, including gene information from Ensembl, protein features from Uniprot/SWISS-PROT, Pfam and DAS-CBS. Gene relationships are fetched from BIND, MINT, KEGG and are integrated with ortholog data from TreeFam to extend the current interaction networks. Integrated tools for primer-design and mis-splicing analysis have been developed to facilitate experimental analysis of individual genes with focus on their variation. Snap is available at http://snap.humgen.au.dk/ and at http://snap.genomics.org.cn/.",
        "keywords": [
            "internet",
            "proteins",
            "experimental analysis",
            "human genome",
            "interaction network",
            "gene regulatory networks",
            "systems integration",
            "single nucleotide polymorphism"
        ],
        "authors": [
            {
                "name": "Shengting Li",
                "org": ""
            },
            {
                "name": "Lijia Ma",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "S\u00f8ren Vang",
                "org": ""
            },
            {
                "name": "Yafeng Hu",
                "org": ""
            },
            {
                "name": "Lars Bolund",
                "org": ""
            },
            {
                "name": "Jun Wang",
                "org": ""
            }
        ],
        "venue": "Nucleic Acids Research",
        "year": 2007
    },
    "tXRz3lHy": {
        "id": "tXRz3lHy",
        "title": "SOAPindel: efficient identification of indels from short paired reads.",
        "abstract": "We present a new approach to indel calling that explicitly exploits that indel differences between a reference and a sequenced sample make the mapping of reads less efficient. We assign all unmapped reads with a mapped partner to their expected genomic positions and then perform extensive de novo assembly on the regions with many unmapped reads to resolve homozygous, heterozygous, and complex indels by exhaustive traversal of the de Bruijn graph. The method is implemented in the software SOAPindel and provides a list of candidate indels with quality scores. We compare SOAPindel to Dindel, Pindel, and GATK on simulated data and find similar or better performance for short indels (<10 bp) and higher sensitivity and specificity for long indels. A validation experiment suggests that SOAPindel has a false-positive rate of \u223c10% for long indels (>5 bp), while still providing many more candidate indels than other approaches.",
        "keywords": [],
        "authors": [
            {
                "name": "Shengting Li",
                "org": "BGI-Shenzhen(BGI-Shenzhen),Qingshuihe, Shenzhen,China"
            },
            {
                "name": "Ruiqiang Li",
                "org": "BGI-Shenzhen(BGI-Shenzhen),Qingshuihe, Shenzhen,China"
            },
            {
                "name": "Heng Li",
                "org": "Broad Institute(Broad Institute of MIT and Harvard,Broad Institute of Harvard and MIT,Broad Institute),Cambridge,United States"
            },
            {
                "name": "Jianliang Lu",
                "org": "BGI-Shenzhen(BGI-Shenzhen),Qingshuihe, Shenzhen,China"
            },
            {
                "name": "Yingrui Li",
                "org": "BGI-Shenzhen(BGI-Shenzhen),Qingshuihe, Shenzhen,China"
            },
            {
                "name": "Lars A. Bolund",
                "org": "BGI-Shenzhen(BGI-Shenzhen),Qingshuihe, Shenzhen,China"
            },
            {
                "name": "Mikkel Heide Schierup",
                "org": "Aarhus Universitet(University of Aarhus,Aarhus University),Arhus,Denmark"
            },
            {
                "name": "Jun Wang",
                "org": "BGI-Shenzhen(BGI-Shenzhen),Qingshuihe, Shenzhen,China"
            }
        ],
        "venue": "Genome research",
        "year": 2013
    },
    "g545eiQb": {
        "id": "g545eiQb",
        "title": "Research on Unauthorized Disposition in Property Law",
        "abstract": "The form of Unauthorized Disposition has been defined in \"Property Law\".The author also investigates the conception and the current modes of real right changing,and analyzes the creditor's rights pattern of modern china from the results and the three different theories about the validity of Unauthorized Disposition under this pattern.The author argues that the legislator should design the form of Unauthorized Disposition by making the Unauthorized Disposition effective in principle and the exceptions of validity.",
        "keywords": [
            "mode of real right changing",
            "the efficiency of the contract",
            "the creditor's rights pattern",
            "Unauthorized Disposition"
        ],
        "authors": [
            {
                "name": "LI Heng",
                "org": "School of Law,Beijing University of Aeronautics and Astronautics,Beijing ,China"
            }
        ],
        "venue": "Journal of Beijing University of Aeronautics and Astronautics(Social Sciences Edition)",
        "year": 2008
    },
    "fFolc8ZV": {
        "id": "fFolc8ZV",
        "title": "On Modal Verbs in Sign Language",
        "abstract": "This study,based on an analysis of the definitions and classifications of modal verbs in sign language,as well as related case study,reveals that the evolution of modal verbs in sign language falls into two grammaticalized paths:First,changing from a notional word in sign language into a steady modal verb;second,gaining access to the system of sign language from gestures. Also,this study analyzes two words indicating possibility in Chinese sign language,and the findings show that the modal verbs in Chinese sign language also follow the said two paths.",
        "keywords": [
            "sign language modal verb necessity possibilities grammaticalized path"
        ],
        "authors": [
            {
                "name": "LI Heng",
                "org": ""
            },
            {
                "name": "WU Ling",
                "org": ""
            }
        ],
        "venue": "Chinese Journal of Special Education",
        "year": 2013
    },
    "749oK0gh": {
        "id": "749oK0gh",
        "title": "A Review of the Researches into the Methodology of Sign Language",
        "abstract": "Since its birth,sign language linguistics has mainly used for reference sound language research methods.Its development has successively followed the track of modern linguistics' structuralism,formalism,functionalism and cognitive positivism,and has reflected theoretical perspectives in different eras.This article reviews the methodologies used in Chinese and foreign sign language literature,introduces the commonly used methodologies,and evaluates their advantages and disadvantages.",
        "keywords": [
            "sign language methodology linguistic theory"
        ],
        "authors": [
            {
                "name": "LI Heng",
                "org": "College of Foreign Languages,Beijing University of Aeronautics and Astronautics,Beijing,"
            }
        ],
        "venue": "Chinese Journal of Special Education",
        "year": 2012
    },
    "aZr7eXz3": {
        "id": "aZr7eXz3",
        "title": "Time-Space Metaphors in Chinese Sign Language",
        "abstract": "There are three kind of horizontal and vertical time-space metaphors in Chinese sign language,including \"up-down\",\"front-back\" and \"left-right\".The analysis shows that the time-space metaphors in Chinese sign language share the similar motivation with the Chinese language,and they both conform to the \"embodinism\" put forward by cognitive linguistics.It must be pointed out that there are also some differences between Chinese and Chinese sign language in the understanding of time-space metaphors.For example,there is no \"back/future,front/back\" metaphor in Chinese sign language.Therefore,it is very important to clarify the incongruity between the two languages in order to adopt more efficient teaching methods to improve deaf people's Chinese learning.",
        "keywords": [
            "Chinese sign language time-space metaphor front-back left-right up-down"
        ],
        "authors": [
            {
                "name": "WU Ling",
                "org": "College of Special Education,Beijing Union University,Beijing,"
            },
            {
                "name": "LI Heng",
                "org": "College of Foreign Languages,Beijing University of Aeronautics and Astronautics,Beijing,"
            }
        ],
        "venue": "Chinese Journal of Special Education",
        "year": 2012
    },
    "IMkVZWGK": {
        "id": "IMkVZWGK",
        "title": "The Basic Methods in Sign Language Corpus Creation",
        "abstract": "Sign language corpus,a practice and a research result of the study of sign language linguistics,has become an independent discipline.It is characterized by representative samples and machine-read language materials.Based on this,this article introduces the methods of constructing sign language corpus:(1) words,objects,and regions are supposed to be selected with the methods used in social linguistics to make the samples representative;(2) in corpus processing,the disadvantages of pure text transcription should be avoided,and multimedia software should be used to segment,transcribe,and annotate the data collected.In addition,this article explains the positive effect of sign language corpus construction on language research.",
        "keywords": [
            "sign language corpus standards of collection basic concepts operating procedure"
        ],
        "authors": [
            {
                "name": "LI Heng",
                "org": "College of Foreign Languages,Beijing University of Aeronautics and Astronautics,Beijing,"
            },
            {
                "name": "WU Ling",
                "org": "College of Special Education,Beijing Union University,Beijing,"
            }
        ],
        "venue": "Chinese Journal of Special Education",
        "year": 2013
    },
    "C1WBo3Cs": {
        "id": "C1WBo3Cs",
        "title": "Sign Language Research from the Perspective of Cognitive Metaphor: A New Paradigm",
        "abstract": "Conceptual metaphor theory in cognitive linguistics is one important approach to analyzing the nature of sign language as well as its cognitive mechanism.From this perspective,we can explore the differences in metaphorical expression between speech language and sign language;discover their common neural bases in order to better explain the uniqueness and systematic process of the metaphorical expression in sign language.The future direction of this study is to draw on the essence of current theory and methodology,set up a new research paradigm for sign language by utilizing traditional metaphor coupled with cognition metaphor.This not only means an expansion of current sign language research,but also a fundamental change to the future direction of sign language.",
        "keywords": [
            "conceptual metaphor sign language speech language research paradigm"
        ],
        "authors": [
            {
                "name": "JIANG Guiying",
                "org": "School of Foreign Languages,Xiamen University,"
            },
            {
                "name": "LI Heng",
                "org": "School of Foreign Languages,Xiamen University,"
            }
        ],
        "venue": "Chinese Journal of Special Education",
        "year": 2011
    },
    "FyoO3JI9": {
        "id": "FyoO3JI9",
        "title": "Motion event integration in Chinese sign language",
        "abstract": "This article examines the lexical patterns of motion events in Chinese Sign Language(CSL). Our study has yielded the following three findings:(1) the two constructions \"Manner verb + Path verb\" and \"Path verb\" are only used to express motion events in CSL, while the latter type is used more frequently in our data, suggesting that CSL shows a tendency towards verb-framed constructions;(2) manner verbs and path verbs in \"Manner verb + Path verb\" serial constructions have the same lexical and grammatical status, so CSL also exhibits characteristics of equipollentframed languages; and (3) the [Manner] component can be expressed by the main verb only in boundary-crossing motion events, which brings some characteristics of satellite-framed languages to CSL. Generally speaking, CSL is a complex verb-framed language with some characteristics found in satellite-framed and equipollent-framed languages.",
        "keywords": [],
        "authors": [
            {
                "name": "Li Heng",
                "org": ""
            },
            {
                "name": "Wu Ling",
                "org": ""
            }
        ],
        "venue": "Modern Foreign Languages",
        "year": 2013
    },
    "Yx92KfM1": {
        "id": "Yx92KfM1",
        "title": "A Review of Pronouns in Sign Language",
        "abstract": "This study reviews the pronoun system of sign language. Firstly, it points out that there is a pronoun system in sign language by clarifying the difference between hearing people's pointing gestures and sign language. Based on this, the paper introduces the definitions and functions of personal pronouns, possessive pronouns, indefinite pronouns, interrogative pronouns, reflexive pronouns, reciprocal pronouns, demonstrative pronouns, and relative pronouns, as well as the possible relationship between them. Also, the paper compares the similarities and differences between different pronouns in a variety of sign languages, and analyses the basic features of Chinese sign language's pronouns and their derivative usages.",
        "keywords": [
            "sign language pronoun pointing gesture"
        ],
        "authors": [
            {
                "name": "WU Ling",
                "org": ""
            },
            {
                "name": "LI Heng",
                "org": ""
            }
        ],
        "venue": "Chinese Journal of Special Education",
        "year": 2013
    },
    "I7uL1NTu": {
        "id": "I7uL1NTu",
        "title": "A Review of the Researches into Hearing-Impaired Children's Sign Language Acquisition",
        "abstract": "In the study of sign language,the research into sign language acquisition is a relatively new research area.This article briefly reviews the research into deaf children's sign language acquisition in the past 50 years,especially in the past decade in terms of phonology,vocabulary,and syntax,and analyzes the characteristics of the research and its tendency.Also,the article gives reflections on the research results,the existing problems and future trends from the perspective of ontology,epistemology and methodology,aiming to provide enlightenment for China's sign language acquisition research.",
        "keywords": [
            "sign language acquisition phonology vocabulary syntax"
        ],
        "authors": [
            {
                "name": "LI Heng",
                "org": "College of Foreign Languages,Beijing University of Aeronautics and Astronautics,Beijing,"
            }
        ],
        "venue": "Chinese Journal of Special Education",
        "year": 2012
    },
    "MQGdTgko": {
        "id": "MQGdTgko",
        "title": "NaY zeolites modified by La~(3+) and Ba~(2+): the effect of synthesis details on surface structure and catalytic performance for lactic acid to acrylic acid",
        "abstract": "Modified NaY zeolites have been widely studied and the modification metal element is normally single, while few researches have been conducted on NaY zeolites modified by two kinds of metals. In our study, a series of La3+ and Ba2+ modified NaY zeolites were synthesized through different impregnation procedures. Lactic acid dehydration to acrylic acid was selected as a probe reaction to test the catalytic performance of these zeolites synthesized. The effects of synthesis details on their pore structures and surface acid/base properties were investigated by means of techniques such as N2 sorption, NH3-TPD and CO2-TPD. The characterization results demonstrated that the samples synthesized by two-step impregnation had more medium acid and base sites inducing better catalytic performance. Moreover, compared with successive impregnations, calcination between two impregnations could endow the samples with much more acid amount. These special surface properties resulted in the improvement of selectivity to acrylic acid during lactic acid dehydration.",
        "keywords": [
            "lactic acid",
            "synthesis details",
            "rare earths",
            "dehydration",
            "acid/base",
            "acid base",
            "surface structure"
        ],
        "authors": [
            {
                "name": "YAN Jie",
                "org": " College of Biotechnology and Pharmaceutical Engineering, Nanjing University of Technology, Nanjing , China"
            },
            {
                "name": "YU Dinghua",
                "org": " College of Biotechnology and Pharmaceutical Engineering, Nanjing University of Technology, Nanjing , China; State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing , China"
            },
            {
                "name": "LI Heng",
                "org": " College of Biotechnology and Pharmaceutical Engineering, Nanjing University of Technology, Nanjing , China"
            },
            {
                "name": "SUN Peng",
                "org": " College of Biotechnology and Pharmaceutical Engineering, Nanjing University of Technology, Nanjing , China"
            },
            {
                "name": "HUANG He",
                "org": " College of Biotechnology and Pharmaceutical Engineering, Nanjing University of Technology, Nanjing , China; State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing , China"
            }
        ],
        "venue": "\u7a00\u571f\u5b66\u62a5(\u82f1\u6587\u7248)",
        "year": 2010
    },
    "uoD4p7V7": {
        "id": "uoD4p7V7",
        "title": "Reaction Kinetics of Sorbitol Catalytic Dehydration to Isosorbide",
        "abstract": "With concentrated sulfuric acid as catalyst,dehydration of sorbitol to isosorbide and its kinetics were studied. Effects of catalyst dosage,reaction temperature and reaction pressure on the dehydration were investigated. Under optimum reaction conditions:m(concentrated sulfuric acid):m(sorbitol) 1:100,3 kPa(absolute pressure),403 K,90 min,yield of isosorbide could reach 80%. A homogeneous reaction kinetics model for sorbitol catalytic dehydration to isosorbide was established. In the two-step reaction for sorbitol dehydration,activation energy and pre-exponential factor for sorbitol to 1,4-sorbitan are 47.92 kJ/mol and 21 655.0 min-1,and those for 1,4-sorbitan to isosorbide are 51.00 kJ/mol and 3 487.9 min-1,respectively. Statistical test showed that the proposed model could well fit the reaction process.",
        "keywords": [
            "1",
            "4-sorbitan",
            "Catalytic dehydration",
            "Concentrated sulfuric acid",
            "Isosorbide",
            "Kinetics model",
            "Sorbitol"
        ],
        "authors": [
            {
                "name": "Xie Yusheng",
                "org": " College of Chemistry and Chemical Engineering,Nanjing University of Technology,Nanjing Jiangsu ,China"
            },
            {
                "name": "Yu Dinghua",
                "org": " College of Life Science and Pharmacy,Nanjing University of Technology,Nanjing Jiangsu ,China; State Key Laboratory of Materials-Oriented Chemical Engineering,Nanjing University of Technology,Nanjing Jiangsu ,China"
            },
            {
                "name": "Sun Peng",
                "org": " College of Life Science and Pharmacy,Nanjing University of Technology,Nanjing Jiangsu ,China"
            },
            {
                "name": "Li Heng",
                "org": " College of Life Science and Pharmacy,Nanjing University of Technology,Nanjing Jiangsu ,China"
            },
            {
                "name": "Zhixian Li",
                "org": "Nanjing University of Technology(Nanjing University of Technology),Nanjing,China"
            }
        ],
        "venue": "Petrochemical Technology",
        "year": 2010
    },
    "SJYy7eIp": {
        "id": "SJYy7eIp",
        "title": "Advances of bio-ethylene",
        "abstract": "The developmental overview and background of bio-ethylene was described.The dehydration catalyst and mechanism of the reaction of ethanol to bio-ethylene was summarized.The key technologic problems in the industrialization of bio-ethylene were analyzed.Considering the importance of bio-ethylene to the strategy of oil-substitute route,the perspective of bio-ethylene is promising.",
        "keywords": [
            "ethanol",
            "bio-ethylene",
            "catalysis",
            "mechanism",
            "dehydration"
        ],
        "authors": [
            {
                "name": "HUANG Ying-ming",
                "org": "China National Center for Biotechnology Development,Beijing ,China"
            },
            {
                "name": "LI Heng",
                "org": "College of Life Science and Pharmaceutical Engineering,Nanjing University of Technology,Nanjing ,China"
            },
            {
                "name": "HUANG Xin-jiang",
                "org": "College of Life Science and Pharmaceutical Engineering,Nanjing University of Technology,Nanjing ,China"
            },
            {
                "name": "HU Yao-chi",
                "org": "College of Life Science and Pharmaceutical Engineering,Nanjing University of Technology,Nanjing ,China"
            },
            {
                "name": "HU Yi",
                "org": "College of Life Science and Pharmaceutical Engineering,Nanjing University of Technology,Nanjing ,China"
            }
        ],
        "venue": "Chinese Journal of Bioprocess Engineering",
        "year": 2008
    },
    "EkYoLxCu": {
        "id": "EkYoLxCu",
        "title": "Study on dehydration of ethanol to ethylene catalyzed by alkaline-earth metal modified HZSM-5",
        "abstract": "The catalytic performance of HZSM-5 modified by alkaline-earth metals Mg,Ca,Ba and Sr,respectively,was investigated in the dehydration reaction of ethanol to ethylene,and the Sr/HZSM-5 showed the best catalytic effect.Then the optimal reaction conditions were obtained through experiments.When catalyzed by 0.5% Sr/HZSM-5 at 220 \u2103,with WHSV and ethanol concentration specified at 2.5 h-1 and 50%,respectively,the conversion rate could reach 99.3% with the ethylene selectivity equating to 99.3%.",
        "keywords": [
            "ethanol",
            "ethylene",
            "HZSM-5",
            "alkaline-earth metal",
            "dehydration"
        ],
        "authors": [
            {
                "name": "HUANG Xin-jiang",
                "org": "College of Life Science and Pharmaceutical Engineering,Nanjing University of Technology,Nanjing ,China"
            },
            {
                "name": "HU Yao-chi",
                "org": "College of Life Science and Pharmaceutical Engineering,Nanjing University of Technology,Nanjing ,China"
            },
            {
                "name": "LI Heng",
                "org": "College of Life Science and Pharmaceutical Engineering,Nanjing University of Technology,Nanjing ,China"
            },
            {
                "name": "HUANG He",
                "org": "College of Life Science and Pharmaceutical Engineering,Nanjing University of Technology,Nanjing ,China"
            },
            {
                "name": "HU Yi",
                "org": "College of Life Science and Pharmaceutical Engineering,Nanjing University of Technology,Nanjing ,China"
            }
        ],
        "venue": "Chemical Reagents",
        "year": 2007
    },
    "RQzk9gxv": {
        "id": "RQzk9gxv",
        "title": "Advances of condensation reactions in ionic liquids",
        "abstract": "This paper focuses on the development of ionic liquids as green solvents or catalysts in various kinds of condensation reactions such as Knoevenagel,Aldol,Wittig,Pechmann,Paal-Knorr,Benzoin,Biginelli,etc.As demonstrated in the paper these condensation reactions could be effectively performed in ionic liquids giving higher yield and selectivity.",
        "keywords": [
            "green solvent",
            "ionic liquids",
            "condensation reaction",
            "selectivity"
        ],
        "authors": [
            {
                "name": "HU Yi",
                "org": "College of Life Science and Pharmaceutical Engineering,Nanjing University of Technology,Nanjing ,China"
            },
            {
                "name": "LI Heng",
                "org": "College of Life Science and Pharmaceutical Engineering,Nanjing University of Technology,Nanjing ,China"
            },
            {
                "name": "KANG Hui",
                "org": "College of Life Science and Pharmaceutical Engineering,Nanjing University of Technology,Nanjing ,China"
            },
            {
                "name": "WEI Ping",
                "org": "College of Life Science and Pharmaceutical Engineering,Nanjing University of Technology,Nanjing ,China"
            }
        ],
        "venue": "Chemical Reagents",
        "year": 2006
    },
    "GQT3TWSW": {
        "id": "GQT3TWSW",
        "title": "N-Alkylation Reaction of N-Monosubstituted Sulfonamides Promoted by Potassium Fluoride in Ionic Liquids",
        "abstract": "The N-alkylation of N-monosubstituted sulfonamides with alkyl halides promoted by KF using ionic liquids as reaction media was reported in this paper. Four different ionic liquids,BF4,BF4 and PF6 were investigated,and PF6 showed the best effect when used as the reaction media,giving the highest yield in the shortest reaction time.Promoted by KF in PF6,N-aryl or N-alkyl monosubstituted sulfonamides could react with various activated halides and unactivated primary halides smoothly.Reactions were performed at 85 \u2103 for 2~10 hours,and thirteen N-alkylation products were obtained with 70%~97% yields.Moreover,the ionic liquid recovered could be reused for three times with no appreciable decrease in yield and reaction rate.As demonstrated in this paper,both KF,which was used as mild base,and the ionic liquid PF6 promoted the alkylation reaction efficiently.",
        "keywords": [
            "potassium fluoride",
            "alkyl halide",
            "sulfonamide",
            "alkylation",
            "ionic liquid"
        ],
        "authors": [
            {
                "name": "HU Yi",
                "org": "College of Life Science and Pharmaceutical Engineering,Nanjing University of Technology,Nanjing "
            },
            {
                "name": "KANG Hui",
                "org": "College of Life Science and Pharmaceutical Engineering,Nanjing University of Technology,Nanjing "
            },
            {
                "name": "LI Heng",
                "org": "College of Life Science and Pharmaceutical Engineering,Nanjing University of Technology,Nanjing "
            },
            {
                "name": "WEI Ping",
                "org": "College of Life Science and Pharmaceutical Engineering,Nanjing University of Technology,Nanjing "
            }
        ],
        "venue": "Chinese Journal of Applied Chemistry",
        "year": 2007
    },
    "trG5PMXf": {
        "id": "trG5PMXf",
        "title": "Clinical application of the PSAD value predicting the change in Gleason score after radical prostatectomy in prostate cancer patients",
        "abstract": "Objective:To investigate the clinical application value of PSAD predict differences in Gleason score between biopsy and radical prostatectomy in prostate cancer patients.Method:We retrospectively analyzed the medical records of 133 patients who underwent a radical prostatectomy.The association between Gleason score changes and age,preoperative Gleason score,prostate-specific antigen(PSA),prostate volume and PSA density were analyzed.We also analyzed the factors that influence upgrading in patients with preoperative Gleason score \u22646 and downgrading in patients with Gleason score \u22657.Result:No difference in Gleason score was noted in 52 cases(39.1%),while a downgrade was noted in 13 cases(10.6%) and upgrade in 68 cases(51.1%).PSAD(P=0.002) was significantly correlated with upgrade,No significant characteristics were found for patients with Gleason score \u22657 who downgrade postoperatively.Based on the ROC analysis,a cut-off value of PSAD >0.2435 was associated with higher incidence of upgrade.Conclusion:Lower Gleason score and higher values of PSA are potential predictors for upgrade in patients who underwent TRUS guided prostate biopsy,influence therapeutic decision-making and prognosis.",
        "keywords": [
            "gleason score",
            "prostate-specific antigen density",
            "prostate cancer"
        ],
        "authors": [
            {
                "name": "ZENG Xing",
                "org": "Department of Urology,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,,China"
            },
            {
                "name": "WANG Zhihua",
                "org": "Department of Urology,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,,China"
            },
            {
                "name": "HU Zhiquan",
                "org": "Department of Urology,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,,China"
            },
            {
                "name": "DENG Kangli",
                "org": "Department of Urology,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,,China"
            },
            {
                "name": "YANG Chunguang",
                "org": "Department of Urology,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,,China"
            },
            {
                "name": "LI Heng",
                "org": "Department of Urology,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,,China"
            },
            {
                "name": "ZHUANG Qianyuan",
                "org": "Department of Urology,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,,China"
            },
            {
                "name": "YE Zhangqun",
                "org": "Department of Urology,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,,China"
            }
        ],
        "venue": "Journal of Clinical Urology",
        "year": 2013
    },
    "0ZO35Zbc": {
        "id": "0ZO35Zbc",
        "title": "Management for Ureteral Stenosis: A Comparison of Robot-Assisted Laparoscopic Ureteroureterostomy and Conventional Laparoscopic Ureteroureterostomy.",
        "abstract": " To describe and analyze our experience of robotic-assisted laparoscopic ureteroureterostomy (RALU) and conventional LU for the repair of ureteral stenosis and compare the differences of safety and efficacy between RALU and LU.  Patients who underwent RALU or LU for ureteral stenosis were retrospectively analyzed. Baseline characteristics, details of stenosis, surgery and some laboratory tests, and follow-up data were collected and analyzed.  Among 126 patients presented with ureteral stenosis, 65 patients underwent RALU and 61 patients underwent LU. All operations were completed successfully without conversion to open surgery. Both groups were comparable in baseline characteristics and details of stenosis. The mean operative time, suturing time, and hospitalization time of patients in RALU group were significantly less than those in LU group. The mean operative time of the RALU group was 126.34 minutes, whereas the mean operative time of the LU group was 176.57 minutes (\u2009<\u2009.001). The average suturing time of RALU and LU was 26.88 and 70.43 minutes, respectively (\u2009<\u2009.001). The mean hospitalization time of RALU and LU was 4.01 and 5.02, respectively (\u2009<\u2009.001). RALU presented a lower degree of leukocytes rise than LU (\u2009<\u2009.001). The mean follow-up time was 29.52 months.  RALU and LU both are safe and feasible for ureteral stenosis with a low incidence of complications. Compared with LU, RALU may be a better choice with shorter operative time, suturing time, postoperative hospitalization time, and slighter inflammation. Further clinical studies of high quality are needed to confirm the priority of RALU.",
        "keywords": [
            "anastomosis",
            "end-to-end",
            "laparoscopic",
            "robotic",
            "ureteral stenosis",
            "ureteroureterostomy"
        ],
        "authors": [
            {
                "name": "Guoliang Sun",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."
            },
            {
                "name": "Libin Yan",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."
            },
            {
                "name": "Wei Ouyang",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."
            },
            {
                "name": "Yucong Zhang",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."
            },
            {
                "name": "Beichen Ding",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."
            },
            {
                "name": "Zheng Liu",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."
            },
            {
                "name": "Xiao Yu",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."
            },
            {
                "name": "Zhiquan Hu",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."
            },
            {
                "name": "Heng Li",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."
            },
            {
                "name": "Shaogang Wang",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."
            },
            {
                "name": "Zhangqun Ye",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."
            }
        ],
        "venue": "Journal of laparoendoscopic & advanced surgical techniques. Part A",
        "year": 2019
    },
    "4ldwRy6J": {
        "id": "4ldwRy6J",
        "title": "LncRNAs expression signatures of renal clear cell carcinoma revealed by microarray.",
        "abstract": "Long noncoding RNAs (lncRNAs) are an important class of pervasive genes involved in a variety of biological functions. They are aberrantly expressed in many types of cancers. In this study, we described lncRNAs profiles in 6 pairs of human renal clear cell carcinoma (RCCC) and the corresponding adjacent nontumorous tissues (NT) by microarray.With abundant and varied probes accounting 33,045 LncRNAs in our microarray, the number of lncRNAs that expressed at a certain level could be detected is 17157. From the data we found there were thousands of lncRNAs that differentially expressed (\u2265 2 fold-change) in RCCC tissues compared with NT and 916 lncRNAs differentially expressed in five or more of six RCCC samples. Compared with NT, many lncRNAs were significantly up-regulated or down-regulated in RCCC. Our data showed that down-regulated lncRNAs were more common than up-regulated ones. ENST00000456816, X91348, BC029135, NR_024418 were evaluated by qPCR in sixty-three pairs of RCCC and NT samples. The four lncRNAs were aberrantly expressed in RCCC compared with matched histologically normal renal tissues.Our study is the first one to determine genome-wide lncRNAs expression patterns in RCCC by microarray. The results displayed that clusters of lncRNAs were aberrantly expressed in RCCC compared with NT samples, which revealed that lncRNAs differentially expressed in tumor tissues and normal tissues may exert a partial or key role in tumor development. Taken together, this study may provide potential targets for future treatment of RCCC and novel insights into cancer biology.",
        "keywords": [
            "gene expression profiling",
            "up regulation",
            "down regulation",
            "gene regulatory networks",
            "real time polymerase chain reaction"
        ],
        "authors": [
            {
                "name": "Gan Yu",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "WeiMin Yao",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Ji Wang",
                "org": "University of California, San Francisco(University of California),San Francisco,United States"
            },
            {
                "name": "Xin Ma",
                "org": "General Hospital of People's Liberation Army(Chinese PLA General Hospital,General Hospital of PLA,General Hospital of Chinese PLA,PLA General Hospital),Beijing,China"
            },
            {
                "name": "Wei Xiao",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Heng Li",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Ding Xia",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Yang Yang",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "KangLi Deng",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Haibing Xiao",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "BoHan Wang",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Xiaolin Guo",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Wei Guan",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Zhiquan Hu",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Yinqi Bai",
                "org": "BGI-Shenzhen(BGI-Shenzhen),Qingshuihe, Shenzhen,China"
            },
            {
                "name": "Hua Xu",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Jihong Liu",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Xu Zhang",
                "org": "General Hospital of People's Liberation Army(Chinese PLA General Hospital,General Hospital of PLA,General Hospital of Chinese PLA,PLA General Hospital),Beijing,China"
            },
            {
                "name": "Zhangqun Ye",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            }
        ],
        "venue": "PloS one",
        "year": 2012
    },
    "MplYZmnl": {
        "id": "MplYZmnl",
        "title": "Study of the use of Boari flap for treating ureteric obstruction and urinary fistula after kidney transplantation(Report of 6 cases)",
        "abstract": "Objective:To study the value of using Boari bladder flaps on treating ureteric obstruction and urinary fistula.Methods:3 recipients developed long or multisegment ureteral strictures,and 3 recipients had urinary fistula unresponsive to nonsurgical treatment within 1 year after kidney transplantation in 221 recipients from January 2000 to May 2004.All 6 cases underwent open surgical management(using Boari flap).Results:All 6 patients had successful reconstruction of the transplant ureter using bladder for substitution,and no recurrent ureteral obstruction was observed after one year following up.One-year survival rate of recipients and allografts were both 100%.Conclusions:Using the bladder for reconstruction via Boari flap is an effective technique for ureteric obstruction and urinary fistula following kidney transplantation.",
        "keywords": [
            "Urinary fistula",
            "Kidney transplantation",
            "Boari flap",
            "Ureteric obstruction"
        ],
        "authors": [
            {
                "name": "WANG Zhendi",
                "org": "1Department of Urology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan ,China"
            },
            {
                "name": "LI Heng",
                "org": "1Department of Urology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan ,China"
            },
            {
                "name": "Zeng Fuqing",
                "org": "1Department of Urology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan ,China"
            }
        ],
        "venue": "Journal of Clinical Urology",
        "year": 2007
    },
    "GsWp0NTw": {
        "id": "GsWp0NTw",
        "title": "Early diagnosis and management of acute respiratory distress syndrome caused by fungal pneumonia after renal transplantation",
        "abstract": "Objective:To study the early diagnosis and management of the patients with acute respiratory distress syndrome (ARDS) caused by fungal pneumonia after renal transplantation.Methods:The clinical data of 6 patients with ARDS caused by fungal pneumonia after renal transplantation in our hospital from January 2002 to October 2005 was retrospectively analyzed. All cases were reduced or stopped dosage of immunosuppressants, treated with intervenous drop infusion of Diflucan\u3001Itraconazole et al. The patients were subjected to non-invasive breathing machine assist ventilation and nutrition supply.Results:Totally 6 patients relieved in 11 to 27 days and recovered in one months.Conclusions:Adjustment of immunosuppressive agents dosage, decisive administration with anti-fungal drugs, early management with non-invasive breathing machine assist ventilation, much dosage glucocorticoid used and effective nutrition supply are important for the treatment of patients with ARDS caused by fungal pneumonia after renal transplantation. The key of early diagnosis lies in combining chest X-ray or sputum culture or bronchoalceolar lavage (BAL) with clinical presentation.",
        "keywords": [
            "Fungus",
            "Renal transplantation",
            "Respiratory distress syndrome",
            "Pneumonia"
        ],
        "authors": [
            {
                "name": "ZHANG Yonghong",
                "org": "1Department of Urology, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology,,, China"
            },
            {
                "name": "ZENG Fuqing",
                "org": "1Department of Urology, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology,,, China"
            },
            {
                "name": "LI Heng",
                "org": "1Department of Urology, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology,,, China"
            }
        ],
        "venue": "Journal of Clinical Urology",
        "year": 2006
    },
    "B3iTkiLB": {
        "id": "B3iTkiLB",
        "title": "Effects of donkey-hide glue reinforcing bone oral solution on expression of VEGF and FGF-2 during fracture healing",
        "abstract": "Objective:To investigate the effects of donkey\u2014hide glue reinforcing bone oral solution (DGRBOS) on expression of VEGF and FGF-2 in bony callus in the process of fracture healing of SD rats\u2019 fracture of tibia,and explore the mechanism of treating fracture with DGRBOS. Methods:Tibia fracture model was set up in SD rat,and 90 SD rats were divided randomly into the DGRBOS group, positive control group and negative control group. Selecting 4,7,14,21 and 28 days in the experiment,the immunohistochemistry method was adopted to detect the change of expression of VEGF and FGF-2. Results:DGRBOS group appeared as the peak of expression VEGF on l4th day after operation,compared with positive control group,significant differences were absent(P>0.05),but there were significant differences between DGRBOS group and negative control group P<0.01. DGRBOS group could make expression of FGF-2 achieve peak value on 7th day after operation,compared to the positive control group:significant differences were absent(P>0.05),and significant differences were present comparing to the negative control group(P<0.01). Conclusion:In the early and metaphase of bone repair,DGRBOS could promote fracture healing,through up-regulating expression of VEGF and FGF-2 at molecular level and promoting preosteoblast and chondroblast caryocinesia,blood vessel growth and osseous anabolism.",
        "keywords": [
            "VEGF",
            "FGF-2",
            "Fracture healing",
            "Donkey-hide glue reinforcing bone oral solution(DGRBOS)"
        ],
        "authors": [
            {
                "name": "LI Heng",
                "org": "Union Hospital,Tongji Medical College,Huazhong University of Technology and Science,Hubei, Wuhan ,China"
            },
            {
                "name": "SHEN Lin",
                "org": "Union Hospital,Tongji Medical College,Huazhong University of Technology and Science,Hubei, Wuhan ,China"
            },
            {
                "name": "LI Liqin",
                "org": "Union Hospital,Tongji Medical College,Huazhong University of Technology and Science,Hubei, Wuhan ,China"
            },
            {
                "name": "YANG Yanping",
                "org": "Union Hospital,Tongji Medical College,Huazhong University of Technology and Science,Hubei, Wuhan ,China"
            },
            {
                "name": "ZHOU Piqi",
                "org": "Union Hospital,Tongji Medical College,Huazhong University of Technology and Science,Hubei, Wuhan ,China"
            },
            {
                "name": "DAI Y",
                "org": "Union Hospital,Tongji Medical College,Huazhong University of Technology and Science,Hubei, Wuhan ,China"
            },
            {
                "name": "LU Furong",
                "org": "Union Hospital,Tongji Medical College,Huazhong University of Technology and Science,Hubei, Wuhan ,China"
            },
            {
                "name": "WU Jialin",
                "org": "Union Hospital,Tongji Medical College,Huazhong University of Technology and Science,Hubei, Wuhan ,China"
            }
        ],
        "venue": "Chinese Journal of Traditional Medical Traumatology & Orthopedics",
        "year": 2006
    },
    "A1qFfYiJ": {
        "id": "A1qFfYiJ",
        "title": "Clinical value of MRU in the diagnosis of primary ureteral carcinoma",
        "abstract": "Objective:To evaluate the value of magnetic resonance urography in the diagnosis of primary ureteral carcinoma.Methods:Comparation of the accuracy of diagosis of MRU with that of ultrasonography\u3001urography(KUB+IVU)\u3001retrograde ureteropyelography and CT scan in diagnosis of ureteral carcinoma were carried out. The original pre-operative diagnostic reports of various imaging facilities were analyzed on account of the results of operation and pathology.Results:MRU could clearly shew the obstructive location of ureter. With regard to the ureteral carcinoma, accuracy of the location diagnosis was 100% and diagnostic rate of the obstructive etiology was 100%. MRU was superior to ultrasonography\u3001KUB+IVU\u3001retrograde ureteropyelography and CT scan used in this study.Conclusions:MRU has an important value in the diagnosis of primary ureteral carcinoma.",
        "keywords": [
            "MRU",
            "Ureteral carcinoma",
            "Clinical application"
        ],
        "authors": [
            {
                "name": "ZENG Fuqing",
                "org": "1Department of Urology, Union Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan, , China"
            },
            {
                "name": "LI Heng",
                "org": "1Department of Urology, Union Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan, , China"
            },
            {
                "name": "DU Yuefeng",
                "org": "1Department of Urology, Union Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan, , China"
            }
        ],
        "venue": "Journal of Clinical Urology",
        "year": 2007
    },
    "W8NHwdHt": {
        "id": "W8NHwdHt",
        "title": "Epigenetic alterations of Kr\u00fcppel-like factor 4 and its tumor suppressor function in renal cell carcinoma.",
        "abstract": "Kr\u00fcppel-like factor 4 (KLF4) is a transcription factor that can have divergent functions in different malignancies. The expression and role of KLF4 in renal cell cancer remain unclear. The purpose of this study is to determine epigenetic alterations and possible roles of KLF4 in renal cell carcinoma. The KLF4 expression in primary renal cell cancer tissues and case-matched normal renal tissues was determined by protein and messenger RNA analyses. The epigenetic alterations were detected by methylation-specific PCR and Sequenom MassARRAY. Kaplan-Meier curves and the log-rank test were used for the survival analysis. The effects of KLF4 on cell growth and epithelial-to-mesenchymal transition (EMT) were determined in renal cancer cell lines after viral-based and RNA activation-mediated overexpression of KLF4. In vivo antitumor activity of KLF4 was evaluated by using stably KLF4-transfected renal cancer cells. KLF4 expression was dramatically decreased in various pathological types of renal cancer and associated with poor survival after nephrectomy. Hypermethylation of KLF4 promoter mainly contributed to its expression suppression. In vitro assays indicated that KLF4 overexpression inhibited renal cancer cell growth and survival. KLF4 overexpression also suppressed renal cancer cell migration and invasion by altering the EMT-related factors. In vivo assay showed that ectopic expression of KLF4 also inhibited tumorigenicity and metastasis of renal cancer. Our results suggest that KLF4 is a putative tumor suppressor gene epigenetically silenced in renal cell cancers by promoter CpG methylation and that it has prognostic value for renal cell progression.",
        "keywords": [],
        "authors": [
            {
                "name": "Heng Li",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Ji Wang",
                "org": "University of California, San Francisco(University of California),San Francisco,United States"
            },
            {
                "name": "Wei Xiao",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Ding Xia",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Bin Lang",
                "org": "Macao Polytechnic Institute(Macao Polytechnic Institute),Macau,Macao"
            },
            {
                "name": "Gan Yu",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Xiaolin Guo",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Wei Guan",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Zhihua Wang",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Zhiquan Hu",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Jihong Liu",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Zhangqun Ye",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Hua Xu",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            }
        ],
        "venue": "Carcinogenesis",
        "year": 2013
    },
    "o7Bq7pCh": {
        "id": "o7Bq7pCh",
        "title": "Percutaneous antegrade balloon dilatation for the treatment of ureteral strictures after renal transplantation",
        "abstract": "Objective To evaluate the safety and efficacy of percutaneous balloon dilatation for the treatment of ureteral stricture after renal transplantation.Methods Data of 6 cases who received percutaneous antegrade balloon dilation when diagnosed as ureteral obstruction after renal transplantation during 2007 to 2011 in our hospital were retrospectively analyzed.All patients underwent percutaneous nephrostomy with B ultrasound guidance.The position of ureteral strictures was diagnosed with anterograde venography.Antegrade balloon dilation and double-J stent in ureter were performed subsequently.The cases changed to open surgery if the initial treatment failed.Results Two cases failed,the stricture length of 1 case was longer than 1cm,and the other case was complicated with urinary fistula and urinoma.The two patients changed to open surgery and were cured.Four patients were successfully treated with one dilatation,the transplant kidney function was stable and no ureteral obstruction was seen during 16-38 months of follow-up.Conclusion Antegrade balloon dilation is a safe,minimally invasive and useful method to treat ureteral strictures after renal transplantation.Open surgery is necessary for patients with dilation failure or other complications.",
        "keywords": [
            "ureteral obstruction",
            "treatment",
            "drainage",
            "kidney transplantation",
            "balloon dilation"
        ],
        "authors": [
            {
                "name": "YANG Hua",
                "org": "Department of Urology,Union Hospital,Huazhong University of Science and Technology,Wuhan ,China"
            },
            {
                "name": "LI Heng",
                "org": "Department of Urology,Union Hospital,Huazhong University of Science and Technology,Wuhan ,China"
            },
            {
                "name": "WANG Zhen-di",
                "org": "Department of Urology,Union Hospital,Huazhong University of Science and Technology,Wuhan ,China"
            },
            {
                "name": "ZENG Fu-qing",
                "org": "Department of Urology,Union Hospital,Huazhong University of Science and Technology,Wuhan ,China"
            }
        ],
        "venue": "Journal of Modern Urology",
        "year": 2013
    },
    "fPdj5yEd": {
        "id": "fPdj5yEd",
        "title": "Fibulin-1 is down-regulated through promoter hypermethylation and suppresses renal cell carcinoma progression.",
        "abstract": "Renal cell carcinoma is one of the most common cancers worldwide but the molecular mechanisms that underlie it are not fully understood. Fibulin-1, a multi-functional extracellular matrix protein, is involved in many types of cancer but its function in renal cell carcinoma is unclear. We investigated fibulin-1 expression and function in renal cell carcinoma.We performed real-time polymerase chain reaction, Western blot analysis and immunohistochemistry to determine fibulin-1 expression in renal cell carcinoma cells and patient tissues. Methylation specific polymerase chain reaction and quantitative sequencing were done to examine the methylation status of the FBLN1 gene promoter. Eukaryotic expression plasmid and a lentiviral vector were used to over express fibulin-1 in ACHN and 786-O renal cell carcinoma cells to investigate its function in vitro and in vivo.Fibulin-1 was significantly down-regulated in renal cell carcinoma cell lines and patient tissues. Dysregulation was associated with renal cell carcinoma progression. The FBLN1 gene promoter region was hypermethylated and its methylation status correlated with fibulin-1 expression. Fibulin-1 over expression led dramatically to decreased cell growth, enhanced tumor cell apoptosis, decreased cell motility and angiogenesis in cultured renal cell carcinoma cells and in xenograft tumors in nude mice.Fibulin-1 is down-regulated in renal cell carcinoma through promoter hypermethylation. It functions as a tumor suppressor and angiogenesis inhibitor in renal cell carcinoma.",
        "keywords": [
            "tumor suppressor",
            "carcinoma",
            "angiogenesis inhibitors",
            "fibulin genes",
            "renal cell",
            "kidney"
        ],
        "authors": [
            {
                "name": "Wei Xiao",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Ji Wang",
                "org": "University of California, San Francisco(University of California),San Francisco,United States"
            },
            {
                "name": "Heng Li",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Wei Guan",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Ding Xia",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Gan Yu",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Haibing Xiao",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Bin Lang",
                "org": "Macao Polytechnic Institute(Macao Polytechnic Institute),Macau,Macao"
            },
            {
                "name": "Xin Ma",
                "org": "General Hospital of People's Liberation Army(Chinese PLA General Hospital,General Hospital of PLA,General Hospital of Chinese PLA,PLA General Hospital),Beijing,China"
            },
            {
                "name": "Jihong Liu",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Xu Zhang",
                "org": "General Hospital of People's Liberation Army(Chinese PLA General Hospital,General Hospital of PLA,General Hospital of Chinese PLA,PLA General Hospital),Beijing,China"
            },
            {
                "name": "Zhangqun Ye",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Hua Xu",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            }
        ],
        "venue": "The Journal of urology",
        "year": 2013
    },
    "F5dyZGUB": {
        "id": "F5dyZGUB",
        "title": "MicroRNA-34a functions as an anti-metastatic microRNA and suppresses angiogenesis in bladder cancer by directly targeting CD44.",
        "abstract": "BackgroundMetastasis have considered as an important clinical obstacle in the treatment of human cancer including bladder cancer. Post-transcriptional regulation has emerged as robust effectors of metastasis. MiRNAs are involved in cancer development and progression, acting as tumor suppressors or oncogenes. In this study, we focus on it that microRNA-34a functions as an anti-metastatic microRNA and suppress angiogenesis in bladder cancer by directly targeting CD44.MethodsThe expression of mir-34a was detected by quantitative real-time PCR. Oligonucleotide and lentivirus were used to overexpress miR-34a. Tube formation assay and transwell assay were used to examine the effect on bladder cancer tube formation, migration and invasion in vitro. Animal models were used to examine the effect on metastasis and angiogenesis in vivo. Luciferase assay was carried out to verify the precise target of miR-34a.ResultsWe not only proved that mir-34a was significantly downregulated in bladder cancer tissues and cell lines but also that circulating miR-34a levels are reduced in bladder cancer, and their levels were positively relevance. Gain-of-function experiments investigated that increased mir-34a expression suppressed tube formation and reduced cell migration and invasion. In vivo metastasis, assays also demonstrated that overexpression of mir34a markedly inhibited bladder cancer metastasis. CD31, an endothelial cell\u00bfspecific marker which stained in T24 tumors to evaluate for blood vessel density, the immunohistochemistry results showed that blood vessel quantification reduced dramatically in the T24 tumors over-expressing mir-34a. Combining with our previous studies and bioinformatics analysis, we expected that CD44 gene was a direct target of mir-34a, siRNA-mediated knockdown of CD44 partially phenocopied mir-34a overexpression suggesting that the pro-apoptotic role of mir-34a may be mediated primarily through CD44 regulation, whereas restoring the expression of CD44 attenuated the function of mir-34a in bladder cancer cells. Additionally, we identified that EMT (epithelial-mesenchymal transition) related proteins could be regulated by mir-34a which indicated that mir-34a could partially reserve EMT.ConclusionOur study defines a major metastasis and angiogenesis suppressive role for mir-34a, a microRNA functions as a tumor suppressor in bladder cancer by directly targeting CD44, which would be helpful as a therapeutic approach to block bladder cancer metastasis.",
        "keywords": [
            "Bladder cancer cell",
            "miR-34a",
            "CD44",
            "Metastatic",
            "Angiogenesis"
        ],
        "authors": [
            {
                "name": "Yu Gan",
                "org": ""
            },
            {
                "name": "Yao Weimin",
                "org": ""
            },
            {
                "name": "Xiao Wei",
                "org": ""
            },
            {
                "name": "Li Heng",
                "org": ""
            },
            {
                "name": "Xu Hua",
                "org": ""
            },
            {
                "name": "Lang Bin",
                "org": ""
            }
        ],
        "venue": "Journal of experimental &amp;amp; clinical cancer research : CR",
        "year": 2014
    },
    "nCdZrMFq": {
        "id": "nCdZrMFq",
        "title": "Diagnose and treatment of cytomegalovirus infection following kidney transplantation",
        "abstract": "Objective To investigate the diagnosis and treatment of the cytomegalovirus (CMV) infection following kidney transplantation.Methods From January 2000 to March 2004,the clinical data of 218 renal allograft recipients were retrospectively analyzed.According to laboratory results and clinical symptoms,57 patients (26%) were diagnosed as having CMV infection,including 24 patients (11%) who developed CMV pneumonia,and adjustment of immunosuppressive agents,anti-infection and supportive treatment followed.Results Seventeen patients were cured and 7 were died.Conclusion Extended prophylaxis,early diagnosis and early treatment should be carried out to cope with CMV infection.",
        "keywords": [
            "kidney transplantation",
            "cytomegalovirus"
        ],
        "authors": [
            {
                "name": "WANG Zhen-di",
                "org": "Department of Urology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan ,China"
            },
            {
                "name": "LI Heng",
                "org": "Department of Urology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan ,China"
            },
            {
                "name": "ZENG Fu-qing",
                "org": "Department of Urology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan ,China"
            }
        ],
        "venue": "Journal of Clinical Surgery",
        "year": 2007
    },
    "dzZU2F7o": {
        "id": "dzZU2F7o",
        "title": "Surgical treatment for patients with duplication of kidney and ureter",
        "abstract": "Objective:To summary and explore the experience of surgical treatment of duplex kidney.Methods:The clinical data and corresponding surgical mode of 29 patients with duplication of kidney and ureter were retrospectively analyzed. Results:Totally 24 oeprations were performed, with 22 patients cured. Of which, 12 cases were examed with B-ultrasound, plain film of kidney-ureter-bladder and intravenous pyelography before removing the double \u201cJ\u201d catheters. The results show that not only degree of hydronephrosis was relieved but also urolithiasis and other affections have disappered.Conclusions:Individualized treatment should be managed in wiew of the function of kidney ,combining what kind of deformity, anatomical position and degree of pathological changes and infection status of urinary tract.",
        "keywords": [
            "Diagnostic hnaging",
            "Surgery",
            "Malformation of kidney and ureter",
            "Urinary system"
        ],
        "authors": [
            {
                "name": "PENG Shibo",
                "org": "1 Department of Urology, Union Hospital, Tongji Medical College, Huazhong University of Science and Tcchnology, Wuhan, , China"
            },
            {
                "name": "ZENG Fuqing",
                "org": "1 Department of Urology, Union Hospital, Tongji Medical College, Huazhong University of Science and Tcchnology, Wuhan, , China"
            },
            {
                "name": "WANG Liang",
                "org": "1 Department of Urology, Union Hospital, Tongji Medical College, Huazhong University of Science and Tcchnology, Wuhan, , China"
            },
            {
                "name": "ZHANG Shilong",
                "org": "1 Department of Urology, Union Hospital, Tongji Medical College, Huazhong University of Science and Tcchnology, Wuhan, , China"
            },
            {
                "name": "LI Heng",
                "org": "1 Department of Urology, Union Hospital, Tongji Medical College, Huazhong University of Science and Tcchnology, Wuhan, , China"
            },
            {
                "name": "JU Wen",
                "org": "1 Department of Urology, Union Hospital, Tongji Medical College, Huazhong University of Science and Tcchnology, Wuhan, , China"
            }
        ],
        "venue": "Journal of Clinical Urology",
        "year": 2007
    },
    "r2yze55E": {
        "id": "r2yze55E",
        "title": "Experience analysis of the treatment for ureteral obstructions after renal transplantation with boari flap ureteroplasty in 10 recipients",
        "abstract": "Objective:To explore the effect and summarize the experience of boari flap ureteroplasty(BFU)for treating the renal transplantation patients with ureteral obstructions.Method:The clinical data and follow-up results of 10 patients undergoing BFU in recent five years were reviewed retrospectively.Patients were examed with B ultrasonography to observe whether there was hydronephrosis or ureteral obstruction in the transplanted kidney.Result:The ureter of all recipients with obstruction were perfectly reconstructed.None of the recipients showed the transplanted uronephrosis or ureteral obstruction,and all of them had normal renal function at one to five years of follow-up.Conclusion:Boari flap ureteroplasty is an effective treatment for the recipients with long segment obstruction of ureter following renal transplantation,and it exhibits satisfactory short-term and long-term curative effect.",
        "keywords": [
            "ureteral obstruction",
            "boari flap",
            "kidney transplantation"
        ],
        "authors": [
            {
                "name": "LI Junping",
                "org": "Department of Urology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,,China"
            },
            {
                "name": "LI Heng",
                "org": "Department of Urology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,,China"
            },
            {
                "name": "JIANG Guosong",
                "org": "Department of Urology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,,China"
            },
            {
                "name": "JIU Quanshuai",
                "org": "Department of Urology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,,China"
            },
            {
                "name": "YANG Hua",
                "org": "Department of Urology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,,China"
            },
            {
                "name": "WANG Zhendi",
                "org": "Department of Urology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,,China"
            },
            {
                "name": "ZENG Fuqing",
                "org": "Department of Urology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,,China"
            }
        ],
        "venue": "Journal of Clinical Urology",
        "year": 2012
    },
    "vZIfbNuB": {
        "id": "vZIfbNuB",
        "title": "Exenatide Reduces Graft Injury in a Rat Transplantation Model Using Kidneys Donated after Cardiac Death.",
        "abstract": "Besides being used in the therapy of type 2 diabetes, exenatide reduces cerebral ischemia-reperfusion (I/R) injury. We evaluated the potential effects of exenatide on inhibition of apoptosis in kidney grafts donated after cardiac death and on reduction of I/R injury after kidney transplantation (KTx) in a rat model. We used a rat syngeneic KTx model with kidney grafts obtained after cardiac death, and apoptosis was detected in the graft before KTx. Graft function, rat survival, morphologic examination, and activation of inflammatory molecules were analyzed after KTx. By the end of the cold storage, exenatide pretreatment donors had significantly reduced caspase pathway activation, terminal deoxynucleotidyl transferase dUTP nick-end labeling--positive cells, release of mitochondrial porin proteins into the cytosol, and expression of cleaved caspase-3 and poly (ADP-ribose) polymerase in kidney grafts. Exenatide pretreatment improved renal function survival rate with lower scores of acute tubular necrosis, infiltrating macrophages, and interstitial fibrosis as well as reduced messenger RNA expression of inflammatory mediators (tumor necrosis factor \u03b1, interleukin-6, interleukin-1\u03b2, and intercellular adhesion molecule-1) after KTx. Our study showed that exenatide reduced I/R injury in kidneys donated after cardiac death in a rat transplantation model and improved recipient survival and graft function.",
        "keywords": "",
        "authors": [
            {
                "name": "Hua Yang",
                "org": "Department of Organ Transplantation, People's Hospital of Jiangxi Province, Nanchang, China."
            },
            {
                "name": "Yuxiang Shi",
                "org": "Department of Pathology, Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."
            },
            {
                "name": "Chengmei Long",
                "org": "Department of Organ Transplantation, People's Hospital of Jiangxi Province, Nanchang, China."
            },
            {
                "name": "Xinchang Li",
                "org": "Department of Organ Transplantation, People's Hospital of Jiangxi Province, Nanchang, China. Electronic address: lixinchang@hotmail.com."
            },
            {
                "name": "Laibang Luo",
                "org": "Department of Organ Transplantation, People's Hospital of Jiangxi Province, Nanchang, China."
            },
            {
                "name": "Miao Chen",
                "org": "Department of Vascular Surgery, People's Hospital of Jiangxi Province, Nanchang, China."
            },
            {
                "name": "Heng Li",
                "org": "Department of Urologic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."
            },
            {
                "name": "Zhendi Wang",
                "org": "Department of Urologic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."
            }
        ],
        "venue": "Transplantation proceedings",
        "year": 2019
    },
    "ckB9ZZZi": {
        "id": "ckB9ZZZi",
        "title": "Effect of Shaoling Plaster on the Expression Level of MMP-3 and RANKL in the Knee Osteoarthritis Patients",
        "abstract": "Objective:To observe the effect of Shaoling plaster for detumescence on serum levels of matrix metalloproteinase-3(MMP-3) and levels of MMP-3 mRNA and receptor activator of nuclear factor kappa B ligand(RANKL)mRNA in peripheral blood mononuclear cell(PBMC) in knee osteoarthritis(OA)patients at various grades.Methods:We did a randomised,double-blind placebo trial,and serum and PBMC were obtained from all people.In both prior-treatment and post-treatment,we measured serum levels of MMP-3 and levels of MMP-3mRNA and RANKLmRNA in PBMC.Symptoms were also scored by Lequesne's index including knee pain at rest,at movement,and at pressure,knee swelling,morning stiffness and walking ability.Results:Compared with findings in the prior-treatment,values for the concentrations of serum MMP-3 and Lequense scores in the post-treatment,were significantly lower in the grade 1 and 2 patients.It is the same to levels of PBMC RANKLmRNA and Lequesne scores in grade 1,and scores of knee pain at pressure and knee swelling in grade 1,2,and 4.In Shaoling plaster for detumescence group,linear logistic regression analysis showed a signifcant postive correlation between concentrations of serum MMP-3 and Lequesne scores in the grade 1 and 2 patients.It was also showed that a signifcant postive correlation between levels of PBMC RANKLmRNA and Lequesne scores in grade 1 patients,and between levels of PBMC RANKLmRNA and scores of knee pain at pressure and knee swelling in grade 1,2,and 4.Conclusion:These findings made us think that during Shaoling plaster for detumescence therapy on knee ostearthiris,one of action mechanism was decreased concentrations of serum MMP-3 by down regulation of MMP-3mRNA expression in synoviocytes and chondrocytes of articular cartilage,sequently amended knee joints failure and improved functions of knee joints in grade 1and grade 2;another is down regulation expression levels of PBMC RANKLmRNA to inhibite osteoclasts' action,to finally achieve the aim for treatment OA patients in grade 1 and active stage.",
        "keywords": [
            "receptor activator of nuclear factor kappa B ligand",
            "matrix metalloproteinase-3",
            "osteoarthritis"
        ],
        "authors": [
            {
                "name": "LI Heng",
                "org": "Union Hospital,Tongji Medical College,Huazhong University of Technology and Science,Wuhan ,Hubei,China"
            },
            {
                "name": "SHEN Lin",
                "org": "Union Hospital,Tongji Medical College,Huazhong University of Technology and Science,Wuhan ,Hubei,China"
            },
            {
                "name": "LI Li-qin",
                "org": "Huazhong University of Technology and Science,Wahan ,Hubei,China"
            },
            {
                "name": "GUO Xiang-fei",
                "org": "Union Hospital,Tongji Medical College,Huazhong University of Technology and Science,Wuhan ,Hubei,China"
            },
            {
                "name": "SHUAI Bo",
                "org": "Union Hospital,Tongji Medical College,Huazhong University of Technology and Science,Wuhan ,Hubei,China"
            }
        ],
        "venue": "Chinese Archives of Traditional Chinese Medicine",
        "year": 2009
    },
    "Vzy1ZSp9": {
        "id": "Vzy1ZSp9",
        "title": "Pseudomonas aeruginosa-mannose-sensitive hemagglutinin inhibits epidermal growth factor receptor signaling pathway activation and induces apoptosis in bladder cancer cells in vitro and in vivo.",
        "abstract": "Pseudomonas aeruginosa-mannose-sensitive hemagglutinin (PA-MSHA), a peritrichous P. aeruginosa strain with MSHA fimbriae, has been shown to be a valuable anticancer drug in many kinds of cancers. However, the effect of PA-MSHA on bladder cancer has not been elucidated. In this study, we focused on the antitumor activities and related mechanisms of PA-MSHA on bladder cancer in vitro and in vivo.SV-40-immortalized normal uroepithelial cells (SV-HUC-1) and human bladder cancer cell lines (T24, 5637, and HT-1376) were treated with PA-MSHA or PA (heat-killed P. aeruginosa). At first, the effect of PA-MSHA on cancer cell proliferation was measured using Cell Counting Assay Kit-8 (CCK-8), whereas the changes of cell morphology were observed by transmission electron microscopy. The early apoptosis induced by PA-MSHA was evaluated by flow cytometry, and the expression level of apoptosis-related molecules was detected using Western blot assay. We then investigated the activation of the epidermal growth factor receptor signaling pathway stimulated by PA-MSHA; the expression and phosphorylation of several key regulators involved in the EGFR signaling pathway were detected. At last, xenograft tumor in nude mice was used to further investigate the antitumor effect of PA-MSHA in vivo.Our results showed that PA-MSHA could efficiently inhibit proliferation and induce apoptosis in human bladder cancer cell lines. Furthermore, cells stimulated with PA-MSHA exhibited an inactivation of EGFR signaling. In vivo, PA-MSHA treatment significantly suppressed tumor growth and induced apoptosis in xenografts tumor in nude mice.PA-MSHA could efficiently inhibit proliferation and induce apoptosis in human bladder cancer cells in vitro and in vivo, which is associated with the inactivation of EGFR signaling pathway, and it might be used as a potential therapeutic agent for bladder cancer.",
        "keywords": [
            "apoptosis",
            "pa-msha",
            "egfr signaling pathway",
            "bladder cancer"
        ],
        "authors": [
            {
                "name": "Lei Chang",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Wei Xiao",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Yang Yang",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Heng Li",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Ding Xia",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Gan Yu",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Xiaolin Guo",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Wei Guan",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Zhiquan Hu",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Hua Xu",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Qianyuan Zhuang",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Zhangqun Ye",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            }
        ],
        "venue": "Urologic oncology",
        "year": 2014
    },
    "BXo6v4v3": {
        "id": "BXo6v4v3",
        "title": "Clone of human KLF4 gene and construction of recombinant KLF4 lentiviral vector",
        "abstract": "BACKGROUND: KLF4 is an essential gene for cell differentiation. OBJECTIVE: To construct a lentiviral vector pCDH-KLF4 gene. METHODS: KLF4 gene amplification was used by PCR. Gene amplification products were inserted into the lentiviral vector pCDH and to co-transfect 293TN cells. DNA sequencing was used to confirm the recombinant vector. The virus supernatant was harvested and titrated. The expression of KLF4 was detected by reverse transcription-PCR. RESULTS AND CONCLUSION: DNA sequencing confirmed that the sequence of amplified KLF4 gene was consistent with the Genebank data. In transfected 5637 cells, KLF4 mRNA was over-expressed. Results verified that lentiviral vevtors of KLF4 gene over-expression were successfully constructed.",
        "keywords": [
            "the National Natural Science Foundation of China",
            "tissue engineering",
            "urinary tract tumors",
            "5637 cells",
            "tissue construction",
            "plasmid vector",
            "cytology experiments in tissue construction",
            "gene recombination",
            "DNA sequencing",
            "DH5a competent cells",
            "lentiviral vector",
            "Escherichia coli",
            "KLF4 gene",
            "tissue construction photographs-containing paper"
        ],
        "authors": [
            {
                "name": "Wang Bo-han",
                "org": " Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan , Hubei Province, China"
            },
            {
                "name": "Yu Xiao",
                "org": " Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan , Hubei Province, China"
            },
            {
                "name": "Yu Gan",
                "org": " Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan , Hubei Province, China"
            },
            {
                "name": "Li Heng",
                "org": " Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan , Hubei Province, China"
            },
            {
                "name": "Xiao Wei",
                "org": " Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan , Hubei Province, China"
            },
            {
                "name": "Xu Hua",
                "org": " Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan , Hubei Province, China"
            },
            {
                "name": "Ye Zhang-qun",
                "org": " Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan , Hubei Province, China"
            }
        ],
        "venue": "Chinese Journal of Tissue Engineering Research",
        "year": 2013
    },
    "KFmbz9wJ": {
        "id": "KFmbz9wJ",
        "title": "Effects of Chinese kidney-tonifying drugs on bone mineral density (BMD), biomechanics, 25-hydroxy vitamin D3 and 1,25-dihydroxy vitamin D3 of ovariectomized osteoporosis rats]",
        "abstract": "To investigate the effects of Chinese kidney-tonifying drugs on bone mineral density, biomechanics, 25-hydroxy Vitamin D3 and 1,25-dihydroxy Vitamin D3 of ovariectomized osteoporosis rats, and explore the mechanism of treating osteoporosis with the drugs.Thirty-six female SD rats (four months) were randomly divided into model group, sham group and treatment group. All the rats had been ovariectomied except those in sham group. Selecting 4, 8, 12 weeks in the experiment, the value of bone mineral density (BMD) was measure by dual energy X-ray absorptiometry (DEXA) of femoral head, while the biomechanics machine was applied to analysis femoral head biomechanics index and ELISA method was used to detect the content of 25-hydroxy Vitamin D3 and 1,25-dihydroxy Vitamin D3 discern in blood-serum, liver and kidney.Treatment group rats' BMD of femoral head was enhance compared with model group, significant differences were absent (P<0.05), and the maximal load and maximal stress measurement were improved, significant differences were absent (P<0.05). As the content of 25-hydroxy Vitamin D3 and 1,25-dihydroxy Vitamin D3 discern in blood-serum, liver and kidney were elevate, furthmore there were significant differences in group comparison, all significant differences were absent (P<0.05). But those compared with sham group, there was no significant difference (P>0.05).In the early period in absence of estrogenic hormone, the Chinese kidney-tonifying drugs could activate bone metabolism to raise BMD and reinforce quality of bone through up-regulating expression of 25-hydroxy Vitamin D3 and 1,25-dihydroxy Vitamin D3 at protein level.",
        "keywords": [],
        "authors": [
            {
                "name": "Shuai Bo",
                "org": "Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China."
            },
            {
                "name": "Shen Lin",
                "org": ""
            },
            {
                "name": "Yang Yan-ping",
                "org": ""
            },
            {
                "name": "Xie Jing",
                "org": ""
            },
            {
                "name": "Zhou Pi-qi",
                "org": ""
            },
            {
                "name": "Li Heng",
                "org": ""
            },
            {
                "name": "Guo Xiang-fei",
                "org": ""
            },
            {
                "name": "Zhao Jia",
                "org": ""
            },
            {
                "name": "Wu Jia-lin",
                "org": ""
            }
        ],
        "venue": "Zhongguo gu shang = China journal of orthopaedics and traumatology",
        "year": 2008
    },
    "dUlZsS5z": {
        "id": "dUlZsS5z",
        "title": "The cause and treatment of the severe pulmonary infection after renal transplantation",
        "abstract": "Objective:To investigate the cause and treatment of the severe pulmonary infection after renal transplantation.Methods:A total of 29 cases severe pulmonary infection after transplantation were retrospectively analyzed. Results: 17 cases out of the 29 severe pulmonary infection patients(58.6%) were rescued successfully,and 12 (41.4%)died from acute respiratory distress syndrome. Conclusions:Severe pulmonary infection is one of the main reasons of death in recipients within 6 months after renal transplantation. The key points of successful treatment involve aggressive reduction or discontinuation of the immunosuppression therapy, the early administration of extended-spectrum and combined antibiotics, identification of pathogens as early as possible, correction of hypoxia and hypoproteinemia.",
        "keywords": [
            "Renal transplantation",
            "Pulmonary infection"
        ],
        "authors": [
            {
                "name": "CAI Zhitao",
                "org": "1Department of Urology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, , China"
            },
            {
                "name": "LI Heng",
                "org": "1Department of Urology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, , China"
            },
            {
                "name": "WANG Zhendi",
                "org": "1Department of Urology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, , China"
            },
            {
                "name": "ZENG Fuqing",
                "org": "1Department of Urology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, , China"
            },
            {
                "name": "GUAN Yongjun",
                "org": "1Department of Urology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, , China"
            },
            {
                "name": "ZHANG Runqing",
                "org": "1Department of Urology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, , China"
            }
        ],
        "venue": "Journal of Clinical Urology",
        "year": 2007
    },
    "oB3gr8H7": {
        "id": "oB3gr8H7",
        "title": "Over-expression of LRIG3 suppresses growth and invasion of bladder cancer cells.",
        "abstract": "The purpose of this study was to investigate the impact of leucine-rich repeats and immunoglobulin-like domains 3 (LRIG3) on the biological features of bladder cancer cell lines. The plasmids of over-expressed LRIG3 and the blank plasmid serving as control were transfected into the bladder cancer cell lines, T24, EJ and BIU-87, and the expression levels of LRIG3 mRNA and protein were detected by using real-time PCR and Western blotting. The changes in the cell cycle and apoptosis were examined by using flow cytometry. The invasive ability was measured by Transwell assay, and CCK-8 assays were used to measure the proliferation of cells. As compared with the control group, the LRIG3 mRNA and protein expression levels in LRIG3 cDNA-transfected group were raised significantly (P<0.05). The average number of cells with up-regulated LRIG3 passing through the inserted filter was decreased significantly as compared with the control group (P<0.05). Up-regulation of LRIG3 also could inhibit proliferation and induce apoptosis of T24, EJ and BIU-87 cells. Except BIU-87, the T24 and EJ cells transfected with LIRG3 cDNA were arrested in G(0)/G(1) phase compared to the control group (P<0.05). In conclusion, the over-expression of LRIG3 could influence the cell cycle and invasion, inhibit proliferation and induce apoptosis in the three bladder cancer cell lines.",
        "keywords": [
            "invasion",
            "apoptosis",
            "lrig3",
            "cell cycle",
            "bladder cancer cell lines"
        ],
        "authors": [
            {
                "name": "Yong QI",
                "org": " Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan , China"
            },
            {
                "name": "Lei CHANG",
                "org": " Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan , China"
            },
            {
                "name": "Heng LI",
                "org": " Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan , China"
            },
            {
                "name": "Gan YU",
                "org": " Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan , China"
            },
            {
                "name": "Wei XIAO",
                "org": " Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan , China"
            },
            {
                "name": "Ding XIA",
                "org": " Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan , China"
            },
            {
                "name": "Wei GUAN",
                "org": " Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan , China"
            },
            {
                "name": "Yang YANG",
                "org": " Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan , China"
            },
            {
                "name": "Bin LANG",
                "org": " School of Health Sciences, Macao Polytechnic Institute, Macao, China"
            },
            {
                "name": "Kang-li DENG",
                "org": " Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan , China"
            },
            {
                "name": "Wei-min YAO",
                "org": " Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan , China"
            },
            {
                "name": "Zhang-qun YE",
                "org": " Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan , China"
            },
            {
                "name": "Qian-yuan ZHUANG",
                "org": " Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan , China"
            }
        ],
        "venue": "Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban",
        "year": 2013
    },
    "eobm4OMo": {
        "id": "eobm4OMo",
        "title": "The Application of Three Dimensional Reconstruction and Virtual Reality Technology in Living Donor Nephrectomy",
        "abstract": "Objective To find a handy way to display the anatomy of the renal arterial and venous systems of potential donors on PC Windows platform. Materials and Methods Dual phase serial computed tomography (CT) images from 10 living related donors were loaded into TGS Amira 3.1 running on a PC with Windows XP. Image crop, segmentation and 3D reconstruction followed. Results We got the video clips as well as the 3D images of donor kidneys and blood vessels. According to the display which was confirmed by latter intraoperative findings, 8 donors had single renal vessels, 1 had a left accessory renal artery and 1 had a right accessory renal artery. Conclusion This project provides a new approach to evaluate the renal vessel anatomy in living donor kidney transplantation, and it is favorable for accuracy and popularizing. As the beneficial supplement of expensive imaging workstations, it is much easier to be learned and manipulated by clinicians, and the clinicians can do their own interpretations according to the raw image data, it absolutely should be favorable for the accuracy of operation.",
        "keywords": [
            "Kidney transplantation Living donor Three dimensional reconstruction"
        ],
        "authors": [
            {
                "name": "WANG Zhendi",
                "org": ",et al. Department of Urology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan,Hubei Province , P.R.China"
            },
            {
                "name": "LI Heng",
                "org": ",et al. Department of Urology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan,Hubei Province , P.R.China"
            },
            {
                "name": "ZENG Fuqing",
                "org": ",et al. Department of Urology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan,Hubei Province , P.R.China"
            }
        ],
        "venue": "Journal of Clinical Radiology",
        "year": 2007
    },
    "hWPjI6pP": {
        "id": "hWPjI6pP",
        "title": "Observation of peripheral blood CD4~+CD25~+ regulatory T cells and analysis of correlation between its proportion and the level of Leptin in posttransplant recipiens",
        "abstract": "Objective:To evaluate the clinical significance of leptin levels and the proportion of CD4+CD25+ regulatory T cells in patient with renal transplantation, to investigate the correlation between its proportion and the level of leptin.Methods:Radio immunoassay was used to evaluate plasma leptin level and Flow cytometry was used to detect the proportion f CD4+CD25+ regulatory T cells in patient with renal transplantation.Results:The level of Leptin measured in kidney transplants patients indicated that there was no significant difference in Leptin level between the control and short term (1 year) posttransplant recipients. But the level of Leptin was higher on long term (2.5 years) posttransplant recipients. The CD4+CD25+ T cells population in posttransplant recipiens was negatively correlated with leptin level(r=-0.83 , P<0.01).Conclusions:The high level of leptin in posttransplant recipiens is correlated with the down-regulation of CD4+CD25+ regulatory T cells, and may not profitable for the maintenance of transplantation tolerance.",
        "keywords": [
            "Leptin",
            "Renal transplantation",
            "CD4+CD25+ regulatory T cells"
        ],
        "authors": [
            {
                "name": "ZHU Wei",
                "org": "1Department of Urology, Union Hospital,Tongji Medical College, Huazhong University of Science and Technology, Wuhan,,China"
            },
            {
                "name": "ZENG Fuqing",
                "org": "1Department of Urology, Union Hospital,Tongji Medical College, Huazhong University of Science and Technology, Wuhan,,China"
            },
            {
                "name": "LI Heng",
                "org": "1Department of Urology, Union Hospital,Tongji Medical College, Huazhong University of Science and Technology, Wuhan,,China"
            }
        ],
        "venue": "Journal of Clinical Urology",
        "year": 2006
    },
    "2J2G5bPa": {
        "id": "2J2G5bPa",
        "title": "miRNA-34a suppresses cell proliferation and metastasis by targeting CD44 in human renal carcinoma cells.",
        "abstract": "We investigated the potential functions of miR-34a in CD44 transcriptional complexes in renal cell carcinoma.We detected miR-34a expression by quantitative real-time polymerase chain reaction. Oligonucleotides were used to over express miR-34a. Cell proliferation and xenograft assays, colony formation and flow cytometry were done to examine effects on cancer cell proliferation in vitro and in vivo. Luciferase assay was performed to verify the precise target of miR-34a.Promoter methylation contributed to miR-34a loss in the ACHN, 786-O and SN12PM6 renal carcinoma cell lines. Ectopic over expression of miR-34a restrained cell growth, tube formation and migration/invasion, and significantly suppressed the growth of renal carcinoma xenografts and metastasis in nude mice. Dual luciferase assay revealed that CD44 was a direct target of miR-34a in renal cancer cells and CD44 knockdown by RNAi in renal cancer cells suppressed tumor progression. In contrast, CD44 ectopic expression partially reversed the antitumor effects of miR-34a in renal cancer cells.Our findings indicate that miR-34a targets CD44 in renal cancer cells and suppresses renal cancer cell growth, tube formation and metastasis in vitro and in vivo. Thus, miR-34a may be a potential molecular target for novel therapeutic strategies for clear cell renal carcinoma.",
        "keywords": [
            "CD44 protein",
            "MIRN34 microRNA",
            "carcinogenesis",
            "carcinoma",
            "human",
            "kidney",
            "renal cell"
        ],
        "authors": [
            {
                "name": "Yu Gan",
                "org": "Department and Institute of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China."
            },
            {
                "name": "Li Heng",
                "org": "Department and Institute of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China."
            },
            {
                "name": "Wang Ji",
                "org": "Department of Cell Death and Cancer Genetics, The Hormel Institute, University of Minnesota, Austin, Minnesota."
            },
            {
                "name": "Gumireddy Kiranmai",
                "org": "The Wistar Institute, Philadelphia, Pennsylvania."
            },
            {
                "name": "Li Anping",
                "org": "The Wistar Institute, Philadelphia, Pennsylvania."
            },
            {
                "name": "Yao Weimin",
                "org": "Department and Institute of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China."
            },
            {
                "name": "Tang Kun",
                "org": "Department and Institute of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China."
            },
            {
                "name": "Xiao Wei",
                "org": "Department and Institute of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China."
            },
            {
                "name": "Hu Junhui",
                "org": "Department and Institute of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China."
            },
            {
                "name": "Xiao Haibing",
                "org": "Department and Institute of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China."
            },
            {
                "name": "Lang Bin",
                "org": "School of Health Sciences, Macao Polytechnic Institute, Macao, People's Republic of China."
            },
            {
                "name": "Ye Zhangqun",
                "org": "Department and Institute of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China."
            },
            {
                "name": "Huang Qihong",
                "org": "The Wistar Institute, Philadelphia, Pennsylvania."
            },
            {
                "name": "Xu Hua",
                "org": "Department and Institute of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China."
            }
        ],
        "venue": "The Journal of urology",
        "year": 2014
    },
    "X14m1BOY": {
        "id": "X14m1BOY",
        "title": "Therapeutic strategies for urinary fistula after renal transplantation(Report of 9 cases)",
        "abstract": "Objective:To investigate the therapeutic strategies for urinary fistula after renal transplantation. Methods:Nine cases were analyzed retrospectively who had been diagnosed with urinary fistula after renal transplantation from 2007 to 2011 in our hospital.All patients underwent conservative treatment first,for example emptying the bladder by indwelling catheter,urine drainage around the bladder and transplant kidney,anti-infection treatment and nutritional support.The cases changed open surgery if the initial treatment failed. Results:Seven patients were successfully treated by conservative treatment,two cases failed and one of them combined urinoma and ureteral stricture,the two patients were cured with open surgery. Conclusions:Conservative treatment is the first choice for urinary fistula after renal transplantation.Open surgery is necessary for the patients who have failure of the previous treatments or combine with other surgical complications.",
        "keywords": [
            "kidney transplantation",
            "therapy",
            "urinary fistula"
        ],
        "authors": [
            {
                "name": "YANG Hua",
                "org": "Department of Urology,Union Hospital,Huazhong University of Science and Technology,Wuhan,,China"
            },
            {
                "name": "WANG Zhendi",
                "org": "Department of Urology,Union Hospital,Huazhong University of Science and Technology,Wuhan,,China"
            },
            {
                "name": "LI Heng",
                "org": "Department of Urology,Union Hospital,Huazhong University of Science and Technology,Wuhan,,China"
            },
            {
                "name": "ZENG Fuqing",
                "org": "Department of Urology,Union Hospital,Huazhong University of Science and Technology,Wuhan,,China"
            }
        ],
        "venue": "Journal of Clinical Urology",
        "year": 2012
    },
    "X7DSjudv": {
        "id": "X7DSjudv",
        "title": "Effects on biological behavior of bladder carcinoma T24 cells via silencing DNMT1 and/or DNMT3b with shRNA in vitro.",
        "abstract": "In this study, RNA interference technique was employed to silence the expression of DNMT1 and/or DNMT3b in human bladder cancer T24 cells. The expression levels of their mRNA and protein were greatly decreased by up to 75% and 65% respectively after T24 cells were transfected with lipofectamine2000 for 72 h, indicating RNA interference is an effective tool in gene knockdown. Proliferation and apoptosis of T24 cells were detected by MTT, and annexin-V-FITC and propidium iodide staining flow cytometry, respectively. It was found that loss of the DNMT1 or DNMT3b expression could inhibit the cell growth and promote the cell apoptosis to some extent. However, combined treatment with shRNA targeting both DNMT1 and DNMT3b mRNA could obviously enhance the above effects. It was concluded that simultaneously silencing both genes could result in strong suppressing effect on tumor proliferation and promoting cell apoptosis than separate use, suggesting combined use of DNMT1 and DNMT3b can achieve a synergistic effect in the CpG island methylation in human bladder tumorigenesis.",
        "keywords": [
            "dnmt1",
            "apoptosis",
            "bladder cancer",
            "dnmt3b",
            "proliferation",
            "flow cytometry",
            "annexin v",
            "rna interference",
            "cell growth"
        ],
        "authors": [
            {
                "name": "Shilong ZHANG",
                "org": " Department of Urology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan , China"
            },
            {
                "name": "Fuqing ZENG",
                "org": " Department of Urology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan , China"
            },
            {
                "name": "Shibo PENG",
                "org": " Department of Urology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan , China"
            },
            {
                "name": "Chaohui ZHU",
                "org": " Department of Urology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan , China"
            },
            {
                "name": "Heng LI",
                "org": " Department of Urology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan , China"
            },
            {
                "name": "Liang WANG",
                "org": " Department of Urology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan , China"
            }
        ],
        "venue": "Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban",
        "year": 2009
    },
    "M2YJ0Dfa": {
        "id": "M2YJ0Dfa",
        "title": "Clinical siginificance of monitoring serum HGF in renal allograft recipients",
        "abstract": "Objective:To study serum HGF in renal allograft recipients with acute rejection, ATN and CsA-induced nephrotoxicity for the clinical significance of early diagnosis and differential diagnosis.Methods:The sequential monitoring of HGF was conducted by ELISA technique in 50 patients before and after renal transplantation.Results:The levels of HGF before transplantation had significant difference in control. The levels of HGF decreased in the first day to third day posttransplantation, decreased and stabilized after about 2 weeks. The levels of HGF increased 1 to 3 days prior to the clinical symptom in acute rejection and serum Cr, increased in ATN and in CsA-induced nephrotoxicity had significant difference in stable group, but HGF level in ATN had no significant difference in CsA-induced nephrotoxicity .In those patients with acute rejection who responded to the treatment, serum HGF level was reduced significantly after antirejection.Conclusions:It suggests that the sequential monitoring of serum HGF of renal allograft recipients can be used to estimate the function of graft, as markers of the early diagnosis and differential diagnosis of acute rejection.",
        "keywords": [
            "Kidney transplantation",
            "Acute rejection",
            "Hepatocyte growth factor"
        ],
        "authors": [
            {
                "name": "XIA Wei",
                "org": "1Department of Urology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, , China"
            },
            {
                "name": "ZENG Fuqing",
                "org": "1Department of Urology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, , China"
            },
            {
                "name": "LI Heng",
                "org": "1Department of Urology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, , China"
            },
            {
                "name": "ZHANG Runqing",
                "org": "1Department of Urology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, , China"
            }
        ],
        "venue": "Journal of Clinical Urology",
        "year": 2006
    },
    "m9o6Fnhi": {
        "id": "m9o6Fnhi",
        "title": "Robot-assisted partial nephrectomy with a standard laparoscopic ultrasound probe in treating endophytic renal tumor.",
        "abstract": "RPN with a standard laparoscopic ultrasound probe is safe, effective and feasible in treating endophytic renal tumor. Our original approach for separating renal mass can avoid some problems caused by the standard laparoscopic ultrasound probe.",
        "keywords": [
            "Retrospective study",
            "Robot-assisted partial nephrectomy",
            "Standard laparoscopic ultrasound probe"
        ],
        "authors": [
            {
                "name": "Yucong Zhang",
                "org": "Department of Urology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Qiaokou, Wuhan, Hubei, 430030, China; Department of Geriatrics, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Qiaokou, Wuhan, Hubei, 430030, China."
            },
            {
                "name": "Wei Ouyang",
                "org": "Department of Urology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Qiaokou, Wuhan, Hubei, 430030, China."
            },
            {
                "name": "Bolin Wu",
                "org": "Department of Urology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Qiaokou, Wuhan, Hubei, 430030, China."
            },
            {
                "name": "Gaurab Pokhrel",
                "org": "Department of Urology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Qiaokou, Wuhan, Hubei, 430030, China."
            },
            {
                "name": "Beichen Ding",
                "org": "Department of Urology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Qiaokou, Wuhan, Hubei, 430030, China."
            },
            {
                "name": "Hao Xu",
                "org": "Department of Urology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Qiaokou, Wuhan, Hubei, 430030, China."
            },
            {
                "name": "Yang Luan",
                "org": "Department of Urology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Qiaokou, Wuhan, Hubei, 430030, China."
            },
            {
                "name": "Yuchao Lu",
                "org": "Department of Urology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Qiaokou, Wuhan, Hubei, 430030, China."
            },
            {
                "name": "Jun Yang",
                "org": "Department of Urology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Qiaokou, Wuhan, Hubei, 430030, China."
            },
            {
                "name": "Zhihua Wang",
                "org": "Department of Urology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Qiaokou, Wuhan, Hubei, 430030, China."
            },
            {
                "name": "Yang Yu",
                "org": "Department of Ultrasonography, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Qiaokou, Wuhan, Hubei, 430030, China."
            },
            {
                "name": "Heng Li",
                "org": "Department of Urology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Qiaokou, Wuhan, Hubei, 430030, China."
            },
            {
                "name": "Wei Guan",
                "org": "Department of Urology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Qiaokou, Wuhan, Hubei, 430030, China."
            },
            {
                "name": "Shaogang Wang",
                "org": "Department of Urology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Qiaokou, Wuhan, Hubei, 430030, China. Electronic address: sgwangtjm@163.com."
            },
            {
                "name": "Zheng Liu",
                "org": "Department of Urology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Qiaokou, Wuhan, Hubei, 430030, China. Electronic address: lz2013tj@163.com."
            }
        ],
        "venue": "Asian journal of surgery",
        "year": 2019
    },
    "x3h6uA0c": {
        "id": "x3h6uA0c",
        "title": "Construction and identification of lentiviral expression vector carrying human Fibulin-5 gene",
        "abstract": "Objective To construct lentiviral expression vector carrying human Fibulin-5 gene.Methods Fibulin-5 gene cloned from pBluescript-Fibulin5 plasmid was double restriction digested as well as lentiviral vector plasmid pCDH-CMV-MCS-EF1.Connection of target gene and vector plasmid was followed to generate the lentiviral expression vector plasmid pCDH-F5.After identification with PCR,double restriction digestion and sequencing of recombinant Fibulin-5 gene,the Fibulin-5 lentiviral expression vector was packaged and used to infect bladder cancer cell line 5637,and then the Fibulin-5 mRNA expression was detected.Results PCR of Fibulin-5 from pCDH-F5 and double restriction digestion of the pCDH-F5 got the same length of gene segment as expected.The sequencing of cloned Fibulin-5 gene was consistent with the described one in the NCBI(NM006329.3) except one mutation,which was further identified to be the same sense mutation.The infective rate of Lenti-F5 to bladder cancer cell line 5637 was more than 95% and the Fibulin-5 gene expression was up-regulated to almost 10-fold level.Conclusions Lentiviral expression vector carrying human Fibulin-5 was successfully constructed.",
        "keywords": [
            "Lentiviral expression vector",
            "Fibulin-5"
        ],
        "authors": [
            {
                "name": "LI Heng",
                "org": ".Department of Urology,Tongji Hospital,Tongji medical College,Huazhong University of Science and Technology,Wuhan ,China"
            },
            {
                "name": "XIAO Wei",
                "org": ".Department of Urology,Tongji Hospital,Tongji medical College,Huazhong University of Science and Technology,Wuhan ,China"
            },
            {
                "name": "YU Gan",
                "org": ".Department of Urology,Tongji Hospital,Tongji medical College,Huazhong University of Science and Technology,Wuhan ,China"
            },
            {
                "name": "YANG Yang",
                "org": ".Department of Urology,Tongji Hospital,Tongji medical College,Huazhong University of Science and Technology,Wuhan ,China"
            },
            {
                "name": "XU Hua",
                "org": ".Department of Urology,Tongji Hospital,Tongji medical College,Huazhong University of Science and Technology,Wuhan ,China"
            },
            {
                "name": "YE Zhang-qun",
                "org": ".Department of Urology,Tongji Hospital,Tongji medical College,Huazhong University of Science and Technology,Wuhan ,China"
            }
        ],
        "venue": "Journal of Contemporary Urologic and Reproductive Oncology",
        "year": 2012
    },
    "iK9k3EIh": {
        "id": "iK9k3EIh",
        "title": "Cisplatin-induced epigenetic activation of miR-34a sensitizes bladder cancer cells to chemotherapy.",
        "abstract": "Accumulating evidence suggests a tumor suppressive role for miR-34a in human carcinogenesis. However, its precise biological role remains largely elusive. This study aimed to reveal the association of the miR-34a expression and its modulation of sensitivity to cisplatin in muscle-invasive bladder cancer (MIBC).miR-34a expression in MIBC cell lines and patient tissues was investigated using qPCR. The methylation analysis of miR-34a promoter region was performed by MassARRAY. Synthetic short single or double stranded RNA oligonucleotides and lentiviral vector were used to regulate miR-34a expression in MIBC cells to investigate its function in vitro and in vivo.miR-34a expression was frequently decreased in MIBC tissues and cell lines through promoter hypermethylation while it was epigenetically increased in MIBC cells following cisplatin treatment. Increased miR-34a expression significantly sensitized MIBC cells to cisplatin and inhibited the tumorigenicity and proliferation of cancer cells in vitro and in vivo. Furthermore, we identified CD44 as being targeted by miR-34a in MIBC cells following cisplatin treatment, and increased CD44 expression could efficiently reverse the effect of miR-34a on MIBC cell proliferation, colongenic potential and chemosensitivity.Cisplatin-based chemotherapy induced demethylation of miR-34a promoter and increased miR-34a expression, which in turn sensitized MIBC cells to cisplatin and decreased the tumorigenicity and proliferation of cancer cells that by reducing the production of CD44.",
        "keywords": [
            "micrornas",
            "oncology",
            "dna methylation",
            "cancer research",
            "transfection"
        ],
        "authors": [
            {
                "name": "Li Heng",
                "org": ""
            },
            {
                "name": "Yu Gan",
                "org": ""
            },
            {
                "name": "Shi Runlin",
                "org": ""
            },
            {
                "name": "Lang Bin",
                "org": ""
            },
            {
                "name": "Chen Xianguo",
                "org": ""
            },
            {
                "name": "Xia Ding",
                "org": ""
            },
            {
                "name": "Xiao Haibing",
                "org": ""
            },
            {
                "name": "Guo Xiaolin",
                "org": ""
            },
            {
                "name": "Guan Wei",
                "org": ""
            },
            {
                "name": "Ye Zhangqun",
                "org": ""
            },
            {
                "name": "Xiao Wei",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China. xiaowei0041@163.com."
            },
            {
                "name": "Xu Hua",
                "org": ""
            }
        ],
        "venue": "Molecular cancer",
        "year": 2014
    },
    "FzTNqoD9": {
        "id": "FzTNqoD9",
        "title": "Clone of human KLF4 gene and construction of recombinant KLF4 lentiviral vector",
        "abstract": "Background: KLF4 is an essential gene for cell differentiation. Objective: To construct a lentiviral vector pCDH-KLF4 gene. Methods: KLF4 gene amplification was used by PCR. Gene amplification products were inserted into the lentiviral vector pCDH and to co-transfect 293TN cells. DNA sequencing was used to confirm the recombinant vector. The virus supernatant was harvested and titrated. The expression of KLF4 was detected by reverse transcription-PCR. Results and Conclusion: DNA sequencing confirmed that the sequence of amplified KLF4 gene was consistent with the Genebank data. In transfected 5637 cells, KLF4 mRNA was over-expressed. Results verified that lentiviral vevtors of KLF4 gene over-expression were successfully constructed.",
        "keywords": [
            "5637 cells",
            "Cytology experiments in tissue construction",
            "DH5a competent cells",
            "DNA sequencing",
            "Escherichia coli",
            "Gene recombination",
            "KLF4 gene",
            "Lentiviral vector",
            "Plasmid vector",
            "The National Natural Science Foundation of China",
            "Tissue construction",
            "Tissue construction photographs-containing paper",
            "Tissue engineering",
            "Urinary tract tumors"
        ],
        "authors": [
            {
                "name": "Bohan Wang",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Xiao Yu",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Gan Yu",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Heng Li",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Wei Xiao",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Hua Xu",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Zhangqun Ye",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            }
        ],
        "venue": "Chinese Journal of Tissue Engineering Research",
        "year": 2013
    },
    "oqqBS2IC": {
        "id": "oqqBS2IC",
        "title": "Analysis on Diagnosis and Treatment of Perirenal Hematoma after Living Relative Kidney Transplantation(Report of 6 Cases)",
        "abstract": "Objective:To discuss the cause and treatment for perirenal hematoma after living relative kidney transplantation.Methods:Totally 6 patients had perirenal hematoma after living relative kidney transplantation. The function of blood coagulation,clinical situation and treatment for the 6 patients were retrospectively analyzed with literature review.Results:6 patients were done examination of coagulation function and color doppler ultrasonography of transplanted renal.All of them have different degrees of coagulation disorders.5 cases were detected perirenal hematoma by color doppler ultrasonography and cleared up by emergency operation,followed up from 1 to 3 months and no recurrence have been observed,serum creatinine ranged from 78.4 to 123.7\u03bcmol/L.1 case missed diagnosis by color doppler ultrasonography due to the hematoma had organized,while diagnosised in operation. Finally he died of multiple organ failure resulted from delayed renal graft function combined with coagulation disorders.Conclusions:Coagulation diaorders was the main cause of postoperative perirenal hematoma in kideny transplant recipients.If the patients have clinical manifestations with reduction of urine,abdominal pain,apophysis of transplanted kidney section,they should been done color doppler ultrasonography to exclude rejection and to definitude whether the oppression of transplanted kidney perirenal hematoma,examine coagulation function at the same time.Color doppler ultrasonography is the preferred diagnostic method,CT or MRI examination could be considered if necessary.However,preoperative and postoperative effectively prevent the coagulation disorders should be emphasized on.",
        "keywords": [
            "living relative donor kidney",
            "perirenal hematoma",
            "kidney transplantation"
        ],
        "authors": [
            {
                "name": "Xin WANG",
                "org": "1 Department of Urology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,,China"
            },
            {
                "name": "Heng LI",
                "org": "1 Department of Urology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,,China"
            },
            {
                "name": "Fuqing ZENG",
                "org": "1 Department of Urology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,,China"
            },
            {
                "name": "Zhendi WANG",
                "org": "1 Department of Urology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,,China"
            },
            {
                "name": "Zhitao CAI",
                "org": "1 Department of Urology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,,China"
            }
        ],
        "venue": "Journal of Clinical Urology",
        "year": 2009
    },
    "RnnzZp9m": {
        "id": "RnnzZp9m",
        "title": "Laparoscopic renal cryoablation versus laparoscopic partial nephrectomy for the treatment of small renal masses: a systematic review and meta-analysis of comparative studies.",
        "abstract": "For small renal masses (SRMs), open partial nephrectomy represents the therapeutic standard of care, and laparoscopic partial nephrectomy (LPN) has provided encouraging outcomes. Laparoscopic renal cryoablation (LRC) could be regarded as an alternative to surgical excision in selected patients, if perioperative complication rates and oncologic results are comparable. However, the short- and long-term outcomes of LRC versus LPN have not been adequately assessed. This study evaluated the safety and efficacy of LRC compared with LPN in the treatment of SRMs.A systematic search of the Medline, Scopus, and CNKI databases and the Cochrane Library was performed up to October 1, 2013. Outcomes of interest assessing the two techniques included demographic and clinical baseline characteristics, surgical and oncological variables, renal function, and complications.Nine eligible trials (555 cases and 642 controls) assessing LRC versus LPN were identified, including two prospective and seven retrospective studies. Patients undergoing LRC were significantly older (weighted mean difference [WMD], 6.48 years; 95% confidence interval [CI], 3.12-9.83; P<.001) and had a higher solitary kidney rate (odds ratio [OR]=3.76; 95% CI, 2.05-6.92; P<.001). Although LRC was associated with shorter operative time (WMD, -54.28 minutes; 95% CI, -83.79 to -24.78; P<.001), less blood loss (WMD, -111.75\u2009mL; 95% CI, -147.96 to -75.53; P<.001), lower risk of conversion (OR=0.17; 95% CI, 0.05-0.60; P=.005), and fewer overall complications (OR=0.53; 95% CI, 0.29-0.98; P=.04), especially the rate of intraoperative complications (OR=0.20; 95% CI, 0.07-0.58; P=.003) and major complications (OR=0.45; 95% CI, 0.25-0.81; P=.008), patients having LPN might still benefit from a significantly lower local recurrence rate (OR=13.03; 95% CI, 4.20-40.39; P<.001) and lower distant metastasis rate (OR=9.05; 95% CI, 2.31-35.51; P=.002).Compared with LPN, LRC was associated with reliable perioperative safety, comparable renal function, and fewer complications; however, LRC may still result in a higher risk of tumor progression. Therefore, our meta-analysis suggested that LRC was associated with worse oncological outcomes than LPN but that LRC may be indicated in selected patients with significant comorbidity. Because of the inherent limitations of the included studies, further large sample, prospective, multicenter, and long-term follow-up studies are awaited to corroborate these findings.",
        "keywords": [],
        "authors": [
            {
                "name": "Tang Kun",
                "org": "1 Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, China ."
            },
            {
                "name": "Yao Weimin",
                "org": ""
            },
            {
                "name": "Li Heng",
                "org": ""
            },
            {
                "name": "Guo Xiaolin",
                "org": ""
            },
            {
                "name": "Guan Wei",
                "org": ""
            },
            {
                "name": "Ma Xin",
                "org": ""
            },
            {
                "name": "Zhang Xu",
                "org": ""
            },
            {
                "name": "Zeng Guohua",
                "org": ""
            },
            {
                "name": "He Wei",
                "org": ""
            },
            {
                "name": "Xu Hua",
                "org": ""
            },
            {
                "name": "Ye Zhangqun",
                "org": ""
            }
        ],
        "venue": "Journal of laparoendoscopic & advanced surgical techniques. Part A",
        "year": 2014
    },
    "c23WGUeQ": {
        "id": "c23WGUeQ",
        "title": "Laparoscopic versus open radical cystectomy in bladder cancer: a systematic review and meta-analysis of comparative studies.",
        "abstract": "More recently laparoscopic radical cystectomy (LRC) has increasingly been an attractive alternative to open radical cystectomy (ORC) and many centers have reported their early experiences in the treatment of bladder cancer. Evaluate the safety and efficacy of LRC compared with ORC in the treatment of bladder cancer.A systematic search of Medline, Scopus, and the Cochrane Library was performed up to Mar 1, 2013. Outcomes of interest assessing the two techniques included demographic and clinical baseline characteristics, perioperative, pathologic and oncological variables, and post-op neobladder function and complications.Sixteen eligible trials evaluating LRC vs ORC were identified including seven prospective and nine retrospective studies. Although LRC was associated with longer operative time (p<0.001), patients might benefit from significantly fewer overall complications (p<0.001), less blood loss (p<0.001), shorter length of hospital stay (p<0.001), less need of blood transfusion (p<0.001), less narcotic analgesic requirement (p<0.001), shorter time to ambulation (p\u200a=\u200a0.03), shorter time to regular diet (p<0.001), fewer positive surgical margins (p\u200a=\u200a0.006), fewer positive lymph node (p\u200a=\u200a0.05), lower distant metastasis rate (p\u200a=\u200a0.05) and fewer death (p\u200a=\u200a0.004). There was no significant difference in other demographic parameters except for a lower ASA score (p\u200a=\u200a0.01) in LRC while post-op neobladder function were similar between the two groups.Our data suggest that LRC appears to be a safe, feasible and minimally invasive alternative to ORC with reliable perioperative safety, pathologic & oncologic efficacy, comparable post-op neobladder function and fewer complications. Because of the inherent limitations of the included studies, further large sample prospective, multi-centric, long-term follow-up studies and randomized control trials should be undertaken to confirm our findings.",
        "keywords": [
            "bioinformatics",
            "biomedical research"
        ],
        "authors": [
            {
                "name": "Tang Kun",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."
            },
            {
                "name": "Li Heng",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."
            },
            {
                "name": "Xia Ding",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."
            },
            {
                "name": "Hu Zhiquan",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."
            },
            {
                "name": "Zhuang Qianyuan",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."
            },
            {
                "name": "Liu Jihong",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."
            },
            {
                "name": "Xu Hua",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."
            },
            {
                "name": "Ye Zhangqun",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."
            }
        ],
        "venue": "PloS one",
        "year": 2014
    },
    "Vb5a1hXa": {
        "id": "Vb5a1hXa",
        "title": "The Immune Checkpoint Regulator PDL1 is an Independent Prognostic Biomarker for Biochemical Recurrence in Prostate Cancer Patients Following Adjuvant Hormonal Therapy.",
        "abstract": ": The programmed death 1 (PD1)/programmed death ligand 1 (PDL1) targeted therapies have gained positive outcomes in several tumors, but the evidence of the expression and prognosis value of PD1/PDL1 in high risk prostate cancer was rare. : Immunohistochemical analysis of PDL1/PD1 expression by a validated antibody was performed in a retrospectively collected high risk prostate cancer cohort who received adjuvant hormonal therapy (AHT) after radical prostatectomy (RP). The association between PDL1/PD1 expression and prognosis was determined. : In total, 127 patients were enrolled. 49.6% patients were considered PDL1-high expression while the PD1-positive expression proportion was 24.4%. High PDL1 and negative PD1 expression were significantly associated with lower prostate specific antigen (PSA) density (p=0.010 and p=0.033, respectively). Compared with the PDL1-low expression patients, the PDL1-high expression patients had significantly shorter time to PSA nadir (TTN) (P=0.001) and biochemical recurrence (BCR) (P=0.004). In Kaplan-Meier analysis, the PDL1-high expression group (p<0.0001) and the PDL1-high/PD1-negative expression group (p<0.0001) showed markedly lower BCR-free survival in localized disease. Univariate cause-specific Cox proportional hazard regression model concluded total PSA (p=0.047), PDL1-high-expression (p<0.001), PDL1-high/PD1-negative expression (p<0.001) were significant risk factors of shorter progression time to BCR in localized disease. PDL1-high-expression was the independent predictor of time to BCR in multiple Cox regression of all patients (Hazard ratio [HR]: 3.901; 95% Confidence interval [CI]: 1.287-11.824; p=0.016). : PDL1 expression is not only highly prevalent in high-risk prostate cancer, but is also an independent biomarker in the prognosis of high-risk prostate cancer received AHT after RP. PDL1/PD1 targeted therapy might be a potentially adjuvant treatment option for high-risk prostate cancer after RP.",
        "keywords": [
            "PD1",
            "PDL1",
            "adjuvant hormonal therapy",
            "biomarker",
            "prostate cancer"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China."
            },
            {
                "name": "Zhize Wang",
                "org": "Department of Urology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, China."
            },
            {
                "name": "Yucong Zhang",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China."
            },
            {
                "name": "Guoliang Sun",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China."
            },
            {
                "name": "Beichen Ding",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China."
            },
            {
                "name": "Libin Yan",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China."
            },
            {
                "name": "Haoran Liu",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China."
            },
            {
                "name": "Wei Guan",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China."
            },
            {
                "name": "Zhiquan Hu",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China."
            },
            {
                "name": "Shaogang Wang",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China."
            },
            {
                "name": "Fei Cheng",
                "org": "Department of Pathology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China."
            },
            {
                "name": "Hua Xu",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China."
            },
            {
                "name": "Xu Zhang",
                "org": "Department of Urology/State Key Laboratory of Kidney Diseases, Chinese PLA General Hospital/PLA Medical School, Beijing 100000, China."
            },
            {
                "name": "Zhangqun Ye",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China."
            }
        ],
        "venue": "Journal of Cancer",
        "year": 2019
    },
    "hEtrnxag": {
        "id": "hEtrnxag",
        "title": "Role of MAPK signal transduction pathway phosphorylation induced by granulocyte-macrophage-colony stimulating factor in the proliferation of hormone-independent prostate cancer]",
        "abstract": "To investigate the phosphorylation intensity of MAPK pathway molecular Erk1/2 and the proliferation of prostate cancer cell line PC-3M.Flow cytometry and RT-PCR were employed to study the ratio of different cell cycles and phases, respectively, before and after GM-CSF stimulation. Erk1/2 phosphorylation intensity was examined by Western blot simultaneously.The rate of PC-3M cells at S and G2/M stages and the expression intensity of Ki-67 increased after GM-CSF incubation in a dose-dependent manner. The phosphorylation intensity of Erk1/2 increased remarkably after stimulation with GM-CSF.The intensification of Erk1/2 phosphorylation is one important molecular mechanism of the proliferation of hormone-independent prostate cancer.",
        "keywords": [
            "cell proliferation",
            "gm-csf",
            "prostate cancer",
            "erk1/2"
        ],
        "authors": [
            {
                "name": "CHEN Zhao-hui",
                "org": "Institute of Urology,"
            },
            {
                "name": "WANG Hua-fang",
                "org": "Institute of Hematology,Union Hospital Affiliated to Tongji Medical College,Huazhong University of Science and Technology,Wuhan,Hubei ,China"
            },
            {
                "name": "JU Wen",
                "org": "Institute of Urology,"
            },
            {
                "name": "LI Heng",
                "org": "Institute of Urology,"
            },
            {
                "name": "XIAO Ya-jun",
                "org": "Institute of Urology,"
            },
            {
                "name": "Zeng Fu-qing",
                "org": "Institute of Urology,"
            },
            {
                "name": "XIAO Chuan-guo",
                "org": "Institute of Urology,"
            }
        ],
        "venue": "Zhonghua nan ke xue = National journal of andrology",
        "year": 2006
    },
    "grhVKtir": {
        "id": "grhVKtir",
        "title": "Choice of the open surgery methods for staghorn renal calculi",
        "abstract": "Objective:To report our experience on open surgery for staghorn renal calculi and the preventive measures of complications. Methods:The clinical data of 23 cases of patients with staghorn renal calculi were analyzed retrospectively. Results:The operations for these 23 patients were carried out with all stones removed successfully. No severe complications noted in all cases. Non in this group lost kidney perioperatively. One month after operation, all patients had their renal function recovered well. Conclusions:Reasonable operation mode should be choosen according to many factors like stone distribution, renal pelvis type and the degree of nephrydrosis. Preoperative and postoperative prevention of infection and sufficient drainage are important strategies for prevention of losing kidney perioperatively.",
        "keywords": [
            "Surgery",
            "Complication",
            "Staghorn renal calculi"
        ],
        "authors": [
            {
                "name": "LI Heng",
                "org": "1Department of Urology,Union Hospital, Huazhong University of Science and Technology,Wuhan,,China"
            },
            {
                "name": "GU Chaohui",
                "org": "1Department of Urology,Union Hospital, Huazhong University of Science and Technology,Wuhan,,China"
            },
            {
                "name": "LIAO Guiyi",
                "org": "1Department of Urology,Union Hospital, Huazhong University of Science and Technology,Wuhan,,China"
            },
            {
                "name": "ZENG Fuqing",
                "org": "1Department of Urology,Union Hospital, Huazhong University of Science and Technology,Wuhan,,China"
            }
        ],
        "venue": "Journal of Clinical Urology",
        "year": 2007
    },
    "NXTBNRKo": {
        "id": "NXTBNRKo",
        "title": "Fibulin-1 is epigenetically down-regulated and related with bladder cancer recurrence.",
        "abstract": "Bladder cancer is one of the most common cancers worldwide. Fibulin-1, a multi-functional extracellular matrix protein, has been demonstrated to be involved in many kinds of cancers, while its function in bladder cancer remains unclear. So here we investigated the expression and function of fibulin-1 in Bladder cancer.We used real-time PCR, Western blot analysis and immunohistochemistry to determine the expression of fibulin-1 in Bladder cancer cells and patient tissues respectively. Methylation-specific PCR and quantitative sequencing were used to examine the methylation status of FBLN1 gene promoter. Eukaryotic expression plasmid and lentiviral vector were used to overexpress fibulin-1 in Bladder cancer cells 5637, HT-1376 to investigate its function in vitro and in vivo.We identified that fibulin-1 was significantly down-regulated in bladder cancer, and its dysregulation was associated with non-muscle-invasive bladder cancer (NMIBC) grade and recurrence. The promoter region of FBLN1 was generally methylated in bladder cancer cell lines and tissues, further investigation in patient tissues showed that the methylation status was associated with the fibulin-1 expression. Overexpression of fibulin-1 significantly suppressed tumor growth, induced tumor cell apoptosis, decreased cell motility, and inhibited angiogenesis in cultured bladder cancer cells and xenograft tumor in nude mice.Altogether, our results indicated that fibulin-1 expression is associated with NMIBC grade and recurrence, it is epigenetically down-regulated and functions as a tumor suppressor gene and angiogenesis inhibitor in bladder cancer.",
        "keywords": [
            "calcium binding proteins",
            "apoptosis",
            "down regulation",
            "risk factors",
            "dna methylation",
            "cell proliferation",
            "gene silencing",
            "stem cells",
            "cancer research",
            "internal medicine",
            "oncology"
        ],
        "authors": [
            {
                "name": "Xiao Wei",
                "org": ""
            },
            {
                "name": "Wang Ji",
                "org": ""
            },
            {
                "name": "Li Heng",
                "org": ""
            },
            {
                "name": "Xia Ding",
                "org": ""
            },
            {
                "name": "Yu Gan",
                "org": ""
            },
            {
                "name": "Yao Weimin",
                "org": ""
            },
            {
                "name": "Yang Yang",
                "org": ""
            },
            {
                "name": "Xiao Haibing",
                "org": ""
            },
            {
                "name": "Lang Bin",
                "org": ""
            },
            {
                "name": "Ma Xin",
                "org": ""
            },
            {
                "name": "Guo Xiaolin",
                "org": ""
            },
            {
                "name": "Guan Wei",
                "org": ""
            },
            {
                "name": "Xu Hua",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China. xuhua@mail.hust.edu.cn."
            },
            {
                "name": "Liu Jihong",
                "org": ""
            },
            {
                "name": "Zhang Xu",
                "org": ""
            },
            {
                "name": "Ye Zhangqun",
                "org": ""
            }
        ],
        "venue": "BMC cancer",
        "year": 2014
    },
    "SJTrjPRB": {
        "id": "SJTrjPRB",
        "title": "Robot-assisted versus laparoscopic adrenalectomy: a systematic review and meta-analysis.",
        "abstract": "More recently, robot-assisted adrenalectomy (RA) has emerged as an attractive alternative to laparoscopic adrenalectomy (LA), and many studies have shown the feasibility and safety of RA. However, the short- and long-term outcomes of RA versus LA have not been adequately assessed, and the advantage over the laparoscopic approach has not been demonstrated. The aim of this study was to compare the outcomes of RA versus LA by means of a systematic review and meta-analysis of the available literature in the early experience.A systematic search of PubMed, SCI/SSCI, CNKI, and the Cochrane Library was performed to identify prospective randomized controlled trials and retrospective observational studies that compared RA and LA and were published between January 2006 to the end of December 2012. Outcomes of interest included demographic and clinical characteristics, perioperative variables, and complications. The meta-analysis was prepared in accordance with the Quality of Reporting of Meta-analyses (QUOROM) statement.Eight trials (232 cases and 297 controls) assessing RA versus LA were considered suitable for meta-analysis, including six prospective and two retrospective studies. There was a significant trend to choose patients for the performance of RA who were associated with a lower body mass index (weighted mean difference [WMD]=-2.78\u2009kg/m(2); 95% confidence interval [CI], -3.00 to -2.55; P<.001) and higher incidence of previous surgery (odds ratio=1.59; 95% CI, 0.99-2.54; P=.05). There were no significant differences between the two groups in any other of the demographic parameters. With regard to perioperative variables, although there was a significant difference in the operating time in favor of LA (WMD=17.52 minutes; 95% CI, 3.48-31.56; P=.01), patients having RA might benefit from significantly less blood loss (WMD=-19.00\u2009mL; 95% CI, -34.58 to -3.41; P=.02) and shorter length of hospital stay (WMD=-0.35 day; 95% CI, -0.51 to -0.19; P<.001). There were no significant differences between RA and LA with regard to conversion rates and overall complications. Sensitivity analysis performed by two methods both showed a positive reversal in the operating time with the statistical significance removed compared with the original analysis.In the early experience, our data suggest that RA, compared with LA, may be a safe and feasible option associated with less blood loss and shorter hospital stay when performed by experienced surgeons in selected patients.",
        "keywords": [],
        "authors": [
            {
                "name": "Tang Kun",
                "org": "Department of Urology and Institute of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, China ."
            },
            {
                "name": "Li Heng",
                "org": ""
            },
            {
                "name": "Xia Ding",
                "org": ""
            },
            {
                "name": "Yu Gan",
                "org": ""
            },
            {
                "name": "Guo Xiaolin",
                "org": ""
            },
            {
                "name": "Guan Wei",
                "org": ""
            },
            {
                "name": "Xu Hua",
                "org": ""
            },
            {
                "name": "Ye Zhangqun",
                "org": ""
            }
        ],
        "venue": "Journal of laparoendoscopic & advanced surgical techniques. Part A",
        "year": 2015
    },
    "XKzw0hXT": {
        "id": "XKzw0hXT",
        "title": "Epigenetic inactivation of KLF4 is associated with urothelial cancer progression and early recurrence.",
        "abstract": "KLF4 is a transcription factor with divergent functions in different malignancies. We analyzed KLF4 expression and DNA methylation, and their clinical relevance and biological function in urothelial cancer.Immunohistochemistry and Sequenom\u2122 MassARRAY\u00ae were done to detect the expression and promoter methylation of KLF4 in urothelial cancer tissues. The association of the recurrence-free survival rate and decreased KLF4 or KLF4 methylation status was analyzed by the Kaplan-Meier method, Cox regression analysis and ROC assay. Lentivirus based KLF4 over expression and dsRNA mediated knockdown were used to detect KLF4 functions in urothelial cancer in vitro and in vivo.KLF4 was down-regulated in urothelial cancer due to promoter hypermethylation. Each correlated with recurrence-free survival in patients with nonmuscle invasive bladder cancer after transurethral resection of bladder cancer, which potentiates them as valuable predictive biomarkers for early recurrence. Moreover, in and ex vivo experiments showed that KLF4 suppressed urothelial cancer cell growth, migration and invasion inhibited the epithelial-to-mesenchymal transition.KLF4 may function as a tumor suppressor gene in urothelial cancer since down-regulation of KLF4 by promoter hypermethylation would promote cancer progression. In addition, decreased expression of KLF4 or its promoter hypermethylation may have predictive value for early recurrence in patients with nonmuscle invasive bladder cancer.",
        "keywords": [
            "tumor suppressor",
            "genes",
            "glyceraldehyde-3-phosphate dehydrogenase",
            "NMIBC",
            "GAPDH",
            "carcinoma",
            "nonmuscle invasive bladder cancer",
            "recurrence-free survival",
            "polymerase chain reaction",
            "TURBT",
            "urothelium",
            "urinary bladder",
            "transurethral resection of bladder tumor",
            "PCR",
            "KLF4",
            "RFS",
            "mortality",
            "5-aza-2-deoxycytidine",
            "EMT",
            "Kr\u00fcppel-like factor 4",
            "epithelial-to-mesenchymal transition",
            "5-AZA-dc"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Ji Wang",
                "org": "University of California, San Francisco(University of California),San Francisco,United States"
            },
            {
                "name": "Wei Xiao",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Ding Xia",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Bin Lang",
                "org": "Macao Polytechnic Institute(Macao Polytechnic Institute),Macau,Macao"
            },
            {
                "name": "Tao Wang",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Xiaolin Guo",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Zhiquan Hu",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Zhangqun Ye",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Hua Xu",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            }
        ],
        "venue": "The Journal of urology",
        "year": 2014
    },
    "e4wg7s3H": {
        "id": "e4wg7s3H",
        "title": "Early diagnosis and management of tuberculous pneumonia after renal transplantation:a report of 12 cases",
        "abstract": "Objective To study the early diagnosis and management of the patients with tuberculosis after renal transplantation.Methods The clinical data of 12 cases of tuberculosis after renal transplantation were retrospectively analyzed.The dose of immunosuppressant was reduced or it was withdrawn,the dose of glucocorticoids was increased,and all patients were subjected to the treatment of isonicotinylhydrazine(INH)+rifampin(RFP)+ethambutol(EB)or pyrazinamide(PZA)and assisted with nutrition supply.Results Twelve patients obtained remission of symptoms in one month,and cured with antituberculotic after 6 to 15 months.Conclusion The key of early diagnosis lies in chest X-ray or tuberculosis culture or PPD or blood antituberculotic antibody,PCR,etc,in combined with clinical presentation.Adjustment of immunosuppressant dosage,decisive administration with antituberculotic and early management with nutrition supply are important for the treatment of patients with tuberculosis after renal transplantation.",
        "keywords": [
            "tuberculosis",
            "combined modality test",
            "renal transplantation"
        ],
        "authors": [
            {
                "name": "KE Zun-jin",
                "org": "Department of Urology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan ,China"
            },
            {
                "name": "ZENG Fu-qing",
                "org": "Department of Urology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan ,China"
            },
            {
                "name": "LI Heng",
                "org": "Department of Urology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan ,China"
            }
        ],
        "venue": "Journal of Clinical Surgery",
        "year": 2007
    },
    "y7cfCQR9": {
        "id": "y7cfCQR9",
        "title": "The Relationship Between Sex Hormones And Regulation T Cells and its Role in Immune Tolerance After Renal Transplantation",
        "abstract": "Objective:Investigate the relevance of sex hormones and the CD4~+CD25~+ Treg, and the their roles in immune tolerance for renal transplantation. Methods:20 patients of normal control group and 20 of Renal transplant patients were selected. ELISA method was employed to detect the sex hormones levels in peripheral blood, the FCM accounting for the CD4~+CD25~+ Treg cells. Results:Compared with the control group, the levels of testosterone gradually increased, and the Estradiol levels gradually decreased as the time correlation after renal transplantation , the level of CD4~+ CD25~+ Treg T cells also increased gradually as the time went on. Exclude the impact of weight, age, dialysis time, HLA matching and other factors ,the sex hormone testosteronel and the level of CD4~+ CD25~+ Treg showed the significant correlation by the linear correlation analysisP<0. 05. Conclusions:After renal transplantation the males not only can inhibit T Lymphocytes directly to play the major immunosuppression, but also can increase the level of regulation T cells to play the secondary immunosuppression.",
        "keywords": [
            "renal transplantation",
            "immune tolerance",
            "sex hormones",
            "CD4~+CD25~+ Treg"
        ],
        "authors": [
            {
                "name": "Yuan YUAN",
                "org": " Department of Urology ,Taihe Hospital Affiliated to Medical College of Yunyang , Shiyan , Hubei,  ,China"
            },
            {
                "name": "Fuqing ZENG",
                "org": " Department of Urology , Union Hospital Affiliated Tongji Medical College, Huazhong University of Technology and Scince"
            },
            {
                "name": "Xiaoqiang ZHAI",
                "org": " Department of Urology , Union Hospital Affiliated Tongji Medical College, Huazhong University of Technology and Scince"
            },
            {
                "name": "Heng LI",
                "org": " Department of Urology , Union Hospital Affiliated Tongji Medical College, Huazhong University of Technology and Scince"
            },
            {
                "name": "Zhendi WANG",
                "org": " Department of Urology , Union Hospital Affiliated Tongji Medical College, Huazhong University of Technology and Scince"
            },
            {
                "name": "Chaohui GU",
                "org": " Department of Urology , Union Hospital Affiliated Tongji Medical College, Huazhong University of Technology and Scince"
            },
            {
                "name": "Liang CHEN",
                "org": " Department of Urology , Union Hospital Affiliated Tongji Medical College, Huazhong University of Technology and Scince"
            }
        ],
        "venue": "Journal of Clinical Urology",
        "year": 2010
    },
    "lhVdc9BC": {
        "id": "lhVdc9BC",
        "title": "MicroRNA-10b promotes migration and invasion through KLF4 and HOXD10 in human bladder cancer.",
        "abstract": "The present study was performed to investigate the effect of microRNA-10b (miR-10b) on cell migration and invasion in human bladder cancer (BC). Real-time PCR was performed to detect the expression of miR-10b in BC cell lines. miR-10b mimics, the negative control for mimics, miR-10b inhibitor and the negative control for inhibitor were transfected into BC cell lines and the effects of miR-10b on the migration and invasion of cells were investigated through Transwell assay. Meanwhile, protein levels of KLF4, HOXD10, E-cadherin and MMP14 were measured. Luciferase assays were also performed to validate KLF4 and HOXD10 as miR-10b targets. In vivo metastasis assay was performed to validate if miR-10b can promote BC cell line metastasis in vivo. miR-10b is significantly upregulated in BC cell lines and metastatic tissues. Increased miR-10b expression significantly enhanced BC cell migration and invasion, while decreased miR-10b expression reduced cell migration and invasion. In vivo metastasis assay demonstrated that overexpression of miR-10b markedly promoted BC metastasis. Moreover, KLF4 and HOXD10 were identified as direct targets of miR-10b in BC cells. Silencing of KLF4 or HOXD10 recapitulated the pro-metastatic function. Furthermore, we found that E-cadherin and MMP14 may be the downstream factors of KLF4 and HOXD10 in the suppression of BC metastasis by miR-10b. These data suggest that miR-10b may function as oncogenes in BC cells. Targeting these novel strategies, inhibition of miR-10b/KLF4/E-cadherin axis and miR-10b/HOXD10/MMP14 axis may be helpful as a therapeutic approach to block BC cell metastasis.",
        "keywords": [
            "cell",
            "oncology",
            "molecular medicine",
            "apoptosis",
            "cancer",
            "gene",
            "cell cycle"
        ],
        "authors": [
            {
                "name": "Xiao Haibing",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, P.R. China."
            },
            {
                "name": "Li Heng",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, P.R. China."
            },
            {
                "name": "Yu Gan",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, P.R. China."
            },
            {
                "name": "Xiao Wei",
                "org": "Translational Medicine Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, P.R. China."
            },
            {
                "name": "Hu Junhui",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, P.R. China."
            },
            {
                "name": "Tang Kun",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, P.R. China."
            },
            {
                "name": "Zeng Jin",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, P.R. China."
            },
            {
                "name": "He Wei",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, P.R. China."
            },
            {
                "name": "Zeng Guohua",
                "org": "Department of Urology, Minimally Invasive Surgery Center, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, P.R. China."
            },
            {
                "name": "Ye Zhangqun",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, P.R. China."
            },
            {
                "name": "Xu Hua",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, P.R. China."
            }
        ],
        "venue": "Oncology reports",
        "year": 2014
    },
    "3XuOQST0": {
        "id": "3XuOQST0",
        "title": "Regulatory Network of Two Tumor-Suppressive Noncoding RNAs Interferes with the Growth and Metastasis of Renal Cell Carcinoma.",
        "abstract": "Noncoding RNAs (ncRNAs) such as microRNAs (miRNAs) and long ncRNAs (lncRNAs) have been shown to function as pivotal regulators in the carcinogenesis of renal cell carcinoma (RCC). However, the functions and underlying mechanisms of most ncRNAs in RCC are still elusive, and the crosstalks of different layers of ncRNAs are seldom reported. Here we showed that miR-124 and maternally expressed gene 3 (MEG3) were both significantly reduced in RCC, and combined expression of miR-124 and MEG3 emerged as an independent prognostic factor in our RCC cohort. Overexpression of miR-124 or MEG3 inhibited cell proliferation, migration, and invasion in\u00a0vitro, and restrained tumor growth in\u00a0vivo. EZH2 knockdown induced the epigenetic silencing of miR-124 and MEG3 expression by H3K27me3. Besides, miR-124 directly targeted the TET1 transcript, and then the interaction resulted in the upregulation of MEG3. Furthermore, we demonstrated that MEG3 induced p53 protein accumulation, whereas p53 was a positive transcriptional regulator of the miR-124. In addition, tumor-suppressive PTPN11 was identified as a direct target of miR-124, as well as the MEG3- and p53-regulated gene. Our study identifies three crosstalks between miR-124 and MEG3, which provide a plausible link for these two ncRNAs in RCC. Both ncRNAs exert important antitumor effects in RCC pathogenesis and might serve as prognostic biomarkers and molecular therapeutic targets.",
        "keywords": [
            "EZH2",
            "MEG3",
            "PTPN11",
            "methylation",
            "miR-124",
            "noncoding RNA",
            "p53",
            "renal cell carcinoma"
        ],
        "authors": [
            {
                "name": "Hui Zhou",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China; Hubei Institute of Urology, Wuhan 430030, China."
            },
            {
                "name": "Kun Tang",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China; Hubei Institute of Urology, Wuhan 430030, China."
            },
            {
                "name": "Haoran Liu",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China; Hubei Institute of Urology, Wuhan 430030, China."
            },
            {
                "name": "Jin Zeng",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China; Hubei Institute of Urology, Wuhan 430030, China."
            },
            {
                "name": "Heng Li",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China; Hubei Institute of Urology, Wuhan 430030, China."
            },
            {
                "name": "Libin Yan",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China; Hubei Institute of Urology, Wuhan 430030, China."
            },
            {
                "name": "Junhui Hu",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China; Hubei Institute of Urology, Wuhan 430030, China."
            },
            {
                "name": "Wei Guan",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China; Hubei Institute of Urology, Wuhan 430030, China."
            },
            {
                "name": "Ke Chen",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China; Hubei Institute of Urology, Wuhan 430030, China."
            },
            {
                "name": "Hua Xu",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China; Hubei Institute of Urology, Wuhan 430030, China. Electronic address: xuhuawhu@163.com."
            },
            {
                "name": "Zhangqun Ye",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China; Hubei Institute of Urology, Wuhan 430030, China."
            }
        ],
        "venue": "Molecular therapy. Nucleic acids",
        "year": 2019
    },
    "YymhzhTr": {
        "id": "YymhzhTr",
        "title": "Exendin-4 ameliorates renal ischemia-reperfusion injury in the rat.",
        "abstract": "Glucagon-like peptide-1 receptor (GLP-1R) activation exerts protective effects against reactive oxygen species by inducing the oxidative defense gene heme oxygenase-1 (HO-1), and provides protection in mice against transient focal cerebral ischemia and ischemia-reperfusion injury in the rat heart. GLP-1R is also expressed in the kidney, but it is unknown whether GLP-1R activation is able to protect against ischemia-reperfusion injury in the rat kidney.We used a rat model of renal ischemia-reperfusion injury. The rats were pretreated with the GLP-1R agonist, exendin-4 before reperfusion. We used real-time polymerase chain reaction to evaluate expression of the oxidative defense gene HO-1 and Western blot analysis for HO-1 and GLP-1R. Renal function was assessed at baseline and 24 and 72 h after reperfusion. The kidneys were processed for histologic and morphometric analysis, caspase-3, and ED1 immunohistochemistry at 72 h. The degree of apoptosis of the renal tubular cells was determined using terminal deoxynucleotidyl transferase deoxyuridine triphosphate-biotin nick end labeling assays.Exendin-4 pretreatment resulted in GLP-1R activation and upregulation of HO-1. Preconditional activation of GLP-1R significantly improved the serum creatinine levels compared with vehicle (P < 0.05). Furthermore, tissue injury, caspase-3 and ED1 expression, and apoptosis were less severe, as quantified by application of a standardized histologic scoring system in a blinded manner.These results have demonstrated that preconditional activation of the GLP-1R with exendin-4 in the kidney significantly protected against ischemia-reperfusion injury in rats by increasing HO-1 expression.",
        "keywords": [
            "exendin-4",
            "renal ischemia-reperfusion",
            "apoptosis",
            "heme oxygenase-1",
            "macrophage",
            "caspase-3",
            "ho-1",
            "male rats",
            "glucagon-like peptide-1",
            "caspase 3"
        ],
        "authors": [
            {
                "name": "Hua Yang",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Heng Li",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Zhendi Wang",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Yuxiang Shi",
                "org": "Central Hospital of Wuhan(The Central Hospital of Wuhan,Central Hospital of Wuhan),Wuhan,China"
            },
            {
                "name": "Guosong Jiang",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Fuqing Zeng",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            }
        ],
        "venue": "The Journal of surgical research",
        "year": 2013
    },
    "nLmqunCd": {
        "id": "nLmqunCd",
        "title": "Effects of Shaolingxiaozeng Tie on serum levels of NO and MMP-9 mRNA in peripheral blood mononuclear cell on knee osteoarthritis patients",
        "abstract": "AIM:To observe the effects of Shaolingxiaozeng Tie on serum levels of nitric oxide(NO) and matrix metalloproteinase-9(MMP-9) mRNA in peripheral blood mononuclear cell(PBMC) on knee osteoarthritis (OA) patients and further to study its mechanism. METHODS: Healthy group (n=21) was established with a randomized, double-blind,placebo,clinical trial research method. Sixty outpatients with knee osteoarthritis were randomly divided into Shaolingxiaozeng Tie(n=39) and placebo (n=21)groups. The treatment lasted for 2 weeks. The serum levels of NO and MMP-9 mRNA in peripheral blood mononuclear cell were measured before and after treatment. The changes of articular genu symptoms such as knee pain at rest and movement, tenderness, knee swelling, morning stiffness and the improvement of walking ability were scored by Lequesne's index before and after treatment. RESULTS: The serum levels of NO and MMP-9 mRNA in PBMC in Shaolingxiaozeng Tie and placebo groups were higher than those in healthy group,there were significant differences (P<0.05). After two weeks' treatment,the serum levels of NO and MMP-9 mRNA in PBMC and Lequesne's score in Shaolingxiaozeng Tie group were lower compared with the foundmental values,there were significant differences (P<0.05). There was signifcant positive correlation between the serum levels of NO and MMP-9 mRNA in PBMC and the knee pain at rest and movement, tenderness, knee swelling, morning stiffness,the walking ability and total Lequesne's score. CONCLUSION: Decreasing the concentration of serum NO and inhibiting the expression of MMP-9 mRNA in PBMC by various ways may be the action mechanisms of Shaolingxiaozeng Tie,so the clinical symptom of osteoarthritis is improved and relieved by inhibiting the apoptosis of chondrocytes and the degradation of cartilage matrix.",
        "keywords": [
            "matrix metalloproteinase-9",
            "nitric oxide",
            "osteoarthritis"
        ],
        "authors": [
            {
                "name": "LI Heng",
                "org": " Department of Combination of TCM with Western Medicine,Union Hospital, Tongji Medical College,Huazhong University of Technology and Science,"
            },
            {
                "name": "SHEN Lin",
                "org": " Department of Combination of TCM with Western Medicine,Union Hospital, Tongji Medical College,Huazhong University of Technology and Science,"
            },
            {
                "name": "LI Li-qin",
                "org": " Life Science and Technology College, Wuhan , Hubei, China"
            },
            {
                "name": "SHUAI Bo",
                "org": " Department of Combination of TCM with Western Medicine,Union Hospital, Tongji Medical College,Huazhong University of Technology and Science,"
            }
        ],
        "venue": "Chinese Journal of Clinical Pharmacology and Therapeutics",
        "year": 2009
    },
    "0kvYdZrS": {
        "id": "0kvYdZrS",
        "title": "The Diagnosis and Treatment of Urinary Fistula After Kidney Transplantation",
        "abstract": "Objective:To discuss the diagnosis and treatment of urinary fistula after renal transplantation,and to lower incidence and mortality of urinary fistula.Methods:From 2003 Jan.to 2007 Dec.the reasons and their positive experience in the diagnosis and treatment of 340 cases with urinary fistula after renal transplantations were reviewed,in order to save renal function and lives of patients.Results:In 340 cases renal transplantations,15 cases were diagnosed as urinary fistula,the incidence of urinary fistula was 4.4%,occurred in 5 to 24 days with mean time 15 days.Conservatively or surgically treatment in 15 cases with success in 14(93.3%),1(6.7%) lost graft and dead.Conclusions:Urinary fistula is a frequency complication after renal transplantation leading to graft losses and patient death.To strengthen the anti-rejection response and prevent the damage of blood supply,the extravesical ureteroneocystostomy and a D-J stent seems feasible to minimize urinary fistula.Early diagnosis and personally treatment are the key.",
        "keywords": [
            "kidney transplantation",
            "urinary fistula"
        ],
        "authors": [
            {
                "name": "Yuan YUAN",
                "org": "1 Department of Urology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,,China"
            },
            {
                "name": "Fuqing ZENG",
                "org": "1 Department of Urology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,,China"
            },
            {
                "name": "Heng LI",
                "org": "1 Department of Urology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,,China"
            },
            {
                "name": "Liang CHEN",
                "org": "1 Department of Urology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,,China"
            }
        ],
        "venue": "Journal of Clinical Urology",
        "year": 2009
    },
    "ynRw5omI": {
        "id": "ynRw5omI",
        "title": "Pseudogene PTENP1 functions as a competing endogenous RNA to suppress clear-cell renal cell carcinoma progression.",
        "abstract": "PTENP1 is a pseudogene of the PTEN tumor suppression gene (TSG). The functions of PTENP1 in clear-cell renal cell carcinoma (ccRCC) have not yet been studied. We found that PTENP1 is downregulated in ccRCC tissues and cells due to methylation. PTENP1 and PTEN are direct targets of miRNA miR21 and their expression is suppressed by miR21 in ccRCC cell lines. miR21 expression promotes ccRCC cell proliferation, migration, invasion in vitro, and tumor growth and metastasis in vivo. Overexpression of PTENP1 in cells expressing miR21 reduces cell proliferation, invasion, tumor growth, and metastasis, recapitulating the phenotypes induced by PTEN expression. Overexpression of PTENP1 in ccRCC cells sensitizes these cells to cisplatin and gemcitabine treatments in vitro and in vivo. In clinical samples, the expression of PTENP1 and PTEN is correlated, and both expressions are inversely correlated with miR21 expression. Patients with ccRCC with no PTENP1 expression have a lower survival rate. These results suggest that PTENP1 functions as a competing endogenous RNA (ceRNA) in ccRCC to suppress cancer progression.",
        "keywords": [],
        "authors": [
            {
                "name": "Yu Gan",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Institute of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."
            },
            {
                "name": "Yao Weimin",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Institute of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."
            },
            {
                "name": "Gumireddy Kiranmai",
                "org": "The Wistar Institute, Philadelphia, Pennsylvania."
            },
            {
                "name": "Li Anping",
                "org": "The Wistar Institute, Philadelphia, Pennsylvania."
            },
            {
                "name": "Wang Ji",
                "org": "Department of Urology and Helen-Diller Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California."
            },
            {
                "name": "Xiao Wei",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Institute of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."
            },
            {
                "name": "Chen Ke",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Institute of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."
            },
            {
                "name": "Xiao Haibing",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Institute of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."
            },
            {
                "name": "Li Heng",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Institute of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."
            },
            {
                "name": "Tang Kun",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Institute of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."
            },
            {
                "name": "Ye Zhangqun",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Institute of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."
            },
            {
                "name": "Huang Qihong",
                "org": "The Wistar Institute, Philadelphia, Pennsylvania. xuhua@mail.hust.edu.cn qhuang@wistar.org."
            },
            {
                "name": "Xu Hua",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Institute of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. xuhua@mail.hust.edu.cn qhuang@wistar.org."
            }
        ],
        "venue": "Molecular cancer therapeutics",
        "year": 2014
    },
    "qWSK2w7w": {
        "id": "qWSK2w7w",
        "title": "Analysis of Early Complications of 86 Living Donor Kidney Transplants",
        "abstract": "Objective:To summarize and analyze the early complications of living donor kidney transplantation (LDKT) and its therapeutic methods.Methods:The clinical data of 86 cases of LDKT cases were retrospectively analyzed November 2003-April 2009.Donor population were comprised of 80 blood related and 6 unrelated(spouse to spouse).All donors underwent open nephrectomy.In 86 cases of recipients,2 cases were second transplantation and the others were the first time.Triple-combined immunosuppressive protocols consisted of calcineurin inhibitor (CND,mycophenolate mofetil(MMF) or azathioprine(Aza) and steroid.Results:All donors' hospital stay was 7 to 10 days postoperatively without any severe surgical complications.All donors kept their normal kidney function within 3 to 12 months' follow-up.Rejection episode occurred in 8 cases,which were reversed by methyl-prednisone or antithymocyte globulin(ATG).Pneumonia developed in 6 cases,of which 4 cases were cured and 2 cases failed,4 cases suffered DGF,one of them accompanied with hematoma,which died because of DIC and MODS.Allograft hematoma requiring surgically removed was found in 6 cases and five cases were cured.Urinary leakage was happened in 6 recepients,who were cured by conservative treatment.83 cases of recipients survived, in which 81 cases kept their normal function kidney and 2 cases occurred chronic allograft nephropathy after one year.Conclusions:LDKT is safe and feasible with good long-term results.The postoperative early complications of transplantation must be diagnosed and treated correctly in early stage,which is important for the long-outcome of patient and graft survival.",
        "keywords": [
            "complication",
            "kidney transplantation",
            "living donors"
        ],
        "authors": [
            {
                "name": "Hua YANG",
                "org": "1 Department of Urology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,,China"
            },
            {
                "name": "Heng LI",
                "org": "1 Department of Urology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,,China"
            },
            {
                "name": "Zhendi WANG",
                "org": "1 Department of Urology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,,China"
            },
            {
                "name": "Changshuai SHAO",
                "org": "1 Department of Urology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,,China"
            },
            {
                "name": "Shuai YUAN",
                "org": "1 Department of Urology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,,China"
            },
            {
                "name": "Weixiong TAO",
                "org": "1 Department of Urology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,,China"
            },
            {
                "name": "Fuqing ZENG",
                "org": "1 Department of Urology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,,China"
            }
        ],
        "venue": "Journal of Clinical Urology",
        "year": 2009
    },
    "X8uePJMb": {
        "id": "X8uePJMb",
        "title": "The Medical Malpractice Legal System in Italy and the References in China",
        "abstract": "Italy's public health system is the second excellent in the world. The Italy has the advanced legislation and experience in dealing with medical malpractice. Italian physicians face both the risk of criminal liability and civil liability. Physicians bear the burden of proof in common medical procedures. Italy has the perfect physician insurance system. In judicial practice, China should increase the proportion of medical malpractice's criminal offenses. The burden of proof should be different in different conditions. And China should establish and improve physician insurance system gradually.",
        "keywords": [
            "medical malpractice legal system medical liability physician insurance"
        ],
        "authors": [
            {
                "name": "Li Heng",
                "org": " Harbin Medical University School of Public Health, Harbin, "
            },
            {
                "name": "Gao Lei",
                "org": " Harbin Medical University School of Public Health, Harbin, "
            },
            {
                "name": "Fan Lihua",
                "org": " Harbin Medical University School of Public Health, Harbin, "
            }
        ],
        "venue": "China Health Law",
        "year": 2011
    },
    "XpeXTCJI": {
        "id": "XpeXTCJI",
        "title": "Studying on the issue of health instant compulsory and right to personal liberty",
        "abstract": "The jurisprudence principle and existing problems of health instant compulsory measure were analyzed.Based on which,countermeasures and suggestions to improve the legal system of health instant compulsory were put forward to regulate the health instant compulsory behaviors,promote construction of health administrative legal system,and safeguard the right to personal liberty.",
        "keywords": [
            "health compulsory measures",
            "health instant compulsory",
            "right to personal liberty."
        ],
        "authors": [
            {
                "name": "Gao Lei",
                "org": "arbin Medical University,Harbin,P.R.China."
            },
            {
                "name": "l H",
                "org": "arbin Medical University,Harbin,P.R.China."
            }
        ],
        "venue": "Chinese Health Service Management",
        "year": 2013
    },
    "eUEyRaEO": {
        "id": "eUEyRaEO",
        "title": "Establishment of BSC&KPI system at grassroots health supervision agency",
        "abstract": "Objective To design a suitable performance evaluation indicators system for grass-roots health supervision agency by using BSC&KPI.MethodsFirst,the environment of the grass-roots agency was analyzed by way of interview and survey,including circumstances,status quo of personnel,organizational structure,duties etc.Second,KPI system was designed based on the logic frame of BSC.Finally,a measurable and intuitionistic result about the performance was given with the fuzzy evaluation method.Results Using the idea of BSC for reference,a performance evaluation project has been designed for health supervision agency,which can comprehensively evaluate the performance of grassroots health supervision agency.Conclusion BSC&KPI system for performance evaluation has been successfully established.",
        "keywords": [
            "key performance indicators(KPI)",
            "health supervision agency",
            "balanced scorecard(BSC)",
            "performance evaluation"
        ],
        "authors": [
            {
                "name": "FAN Li-hua",
                "org": "College of Public Health,Harbin Medical University,Harbin,Heilongjiang "
            },
            {
                "name": "LIU Heng-hui",
                "org": "College of Public Health,Harbin Medical University,Harbin,Heilongjiang "
            },
            {
                "name": "LI Heng",
                "org": "College of Public Health,Harbin Medical University,Harbin,Heilongjiang "
            },
            {
                "name": "QI Ying",
                "org": "College of Public Health,Harbin Medical University,Harbin,Heilongjiang "
            }
        ],
        "venue": "Chinese Rural Health Service Administration",
        "year": 2009
    },
    "hQXxJFcj": {
        "id": "hQXxJFcj",
        "title": "Claims, liabilities, injures and compensation payments of medical malpractice litigation cases in China from 1998 to 2011.",
        "abstract": "Although China experienced great improvement in their health system, disputes between patients and doctors have increasingly intensified, reaching an unprecedented level. Retrospective analysis of medical malpractice litigation can discover the characteristics and fundamental cause of these disagreements.We analyzed medical malpractice litigation data from 1998 to 2011 for characteristics of claims via a litigation database within a nationwide database of cases (1086 cases) in China, including claims, liabilities, injures, and compensation payments.Among the cases analyzed, 76 percent of claims received compensation in civil judgment (640 out of 841), while 93 percent were fault liability in paid judgment (597 out of 640). The average time span between the occurrence of the injury dispute and closure of claims was 3 years. Twenty-two percent of claims (183 of 841) were caused by injury, poisoning, and other external causes. Seventy-nine percent of claims (472 of 597) were contributed to by errors in medical technology. The median damage compensation payment for death was significantly lower than for serious injuries (P < 0.001; death, $13270 [IQR, $7617-$23181]; serious injury, $23721 [IQR, $10367-$57058]). Finally, there was no statistically significant difference in the median mental compensation between minor injury, serious injury, and death (P = 0.836).The social reasons for the conflict and high payment were catastrophic out-of-pocket health-care expense in addition to the high expectations for treatment in China. There were no distinguishing features between China and other countries with respect to time of suits, facilities, and specialties in these claims. The compensation for damages in different medical injuries was unfair in China.",
        "keywords": [
            "public health",
            "health administration",
            "health informatics"
        ],
        "authors": [
            {
                "name": "Li Heng",
                "org": ""
            },
            {
                "name": "Wu Xiangcheng",
                "org": ""
            },
            {
                "name": "Sun Tao",
                "org": ""
            },
            {
                "name": "Li Li",
                "org": ""
            },
            {
                "name": "Zhao Xiaowen",
                "org": ""
            },
            {
                "name": "Liu Xinyan",
                "org": ""
            },
            {
                "name": "Gao Lei",
                "org": ""
            },
            {
                "name": "Sun Quansheng",
                "org": ""
            },
            {
                "name": "Zhang Zhong",
                "org": ""
            },
            {
                "name": "Fan Lihua",
                "org": "Department of Health Management, School of Public Health, Harbin Medical University, Xuefu Road, Harbin, China. lihuafan@126.com."
            }
        ],
        "venue": "BMC health services research",
        "year": 2014
    },
    "kBmxUGrk": {
        "id": "kBmxUGrk",
        "title": "Analysis of Health Administrative Litigation Cases and Research on Health Supervision",
        "abstract": "Objective: This paper studies 154 health administrative litigation cases from 1998 to 2010 to learn the situation and problems,which present from the cases and give basis and suggestions to improve the quality of heath inspection.Methods: Questionnaire are designed for the 154 cases and filled up including the years and classifications of inspection and so on.Then the paper makes a research on the data statistic.Results: In the 154 cases,54 cases are about the medical institution inspection,50 cases are about the medical staff inspection,20 cases are about the food safety inspection.There are 30 cases that the bodies of health administrative lose the suits,and 10 cases that the administrative departments compensate for the plaintiff.Conclusion: To boost the health administrative personnel's education of law,enhance the ability of health inspection,establish the good service conception,improve the health inspector auditing systems can reduce the litigation.",
        "keywords": [
            "Health administrative litigation",
            "Enforcement of health inspection",
            "Health inspection"
        ],
        "authors": [
            {
                "name": "Li heng",
                "org": "et al Harbin Medical University School of Public Health,Harbin,"
            }
        ],
        "venue": "Medicine and Society",
        "year": 2012
    },
    "47dPthKZ": {
        "id": "47dPthKZ",
        "title": "Legal Thinking of Individual Information Safety in Resident Health Archives",
        "abstract": "Residents health archives are an important part of national Basic Community Public Health Care.With the development of resident health archives,personal information security problems have caused the social concern.This article discussed some legal problems about the legal protection of residents' health archives,the collection,safekeeping and application of resident health information,to give suggestions to protect individual information safety in residents' health archives from perspective of legislation.",
        "keywords": [
            "Resident health archives",
            "Individual information",
            "Privacy"
        ],
        "authors": [
            {
                "name": "Gao Lei",
                "org": "ealth Management College of Harbin Medical University,Harbin,"
            },
            {
                "name": "l H",
                "org": "ealth Management College of Harbin Medical University,Harbin,"
            }
        ],
        "venue": "Medicine and Society",
        "year": 2012
    },
    "BcJ2DFWt": {
        "id": "BcJ2DFWt",
        "title": "Work stress, work motivation and their effects on job satisfaction in community health workers: a cross-sectional survey in China.",
        "abstract": "It is well documented that both work stress and work motivation are key determinants of job satisfaction. The aim of this study was to examine levels of work stress and motivation and their contribution to job satisfaction among community health workers in Heilongjiang Province, China.Cross-sectional survey.Heilongjiang Province, China.The participants were 930 community health workers from six cities in Heilongjiang Province.Multistage sampling procedures were used to measure socioeconomic and demographic status, work stress, work motivation and job satisfaction. Logistic regression analysis was performed to assess key determinants of job satisfaction.There were significant differences in some subscales of work stress and work motivation by some of the socioeconomic characteristics. Levels of overall stress perception and scores on all five work stress subscales were higher in dissatisfied workers relative to satisfied workers. However, levels of overall motivation perception and scores on the career development, responsibility and recognition motivation subscales were higher in satisfied respondents relative to dissatisfied respondents. The main determinants of job satisfaction were occupation; age; title; income; the career development, and wages and benefits subscales of work stress; and the recognition, responsibility and financial subscales of work motivation.The findings indicated considerable room for improvement in job satisfaction among community health workers in Heilongjiang Province in China. Healthcare managers and policymakers should take both work stress and motivation into consideration, as two subscales of work stress and one subscale of work motivation negatively influenced job satisfaction and two subscales of work motivation positively influenced job satisfaction.",
        "keywords": [
            "public health",
            "bioinformatics",
            "biomedical research"
        ],
        "authors": [
            {
                "name": "Li Li",
                "org": "Department of Health Management, School of Public Health, Harbin Medical University, Harbin, China."
            },
            {
                "name": "Hu Hongyan",
                "org": "Research Service Office, The Second Affiliated Hospital, Harbin Medical University, Harbin, China."
            },
            {
                "name": "Zhou Hao",
                "org": "Department of Emergency, Harbin Center for Disease Control and Prevention, Harbin, China."
            },
            {
                "name": "He Changzhi",
                "org": "Department of Health Management, School of Public Health, Harbin Medical University, Harbin, China."
            },
            {
                "name": "Fan Lihua",
                "org": "Department of Health Management, School of Public Health, Harbin Medical University, Harbin, China."
            },
            {
                "name": "Liu Xinyan",
                "org": "Department of Health Management, School of Public Health, Harbin Medical University, Harbin, China."
            },
            {
                "name": "Zhang Zhong",
                "org": "Department of Health Management, School of Public Health, Harbin Medical University, Harbin, China."
            },
            {
                "name": "Li Heng",
                "org": "Department of Health Management, School of Public Health, Harbin Medical University, Harbin, China."
            },
            {
                "name": "Sun Tao",
                "org": "Department of Health Management, School of Public Health, Harbin Medical University, Harbin, China."
            }
        ],
        "venue": "BMJ open",
        "year": 2014
    },
    "TbpquqcK": {
        "id": "TbpquqcK",
        "title": "Construct measurement index system of public satisfaction of Social medical insurance",
        "abstract": "Basic on the American customer satisfaction index,construct public satisfaction index model and measurement index system of social medical insurance,including 7 variables:public information,public expectation,perceived quality,perceived worth,public satisfaction and public trust;according to different social medical insurance system characteristic,we divided 7 variables into idiographic three levels indicators and four levels indicators;and then quantified indicators and determined the weight,as well as tested the reliability and validity.",
        "keywords": [
            "American customer satisfaction index",
            "public satisfaction",
            "measurement index",
            "social medical insurance"
        ],
        "authors": [
            {
                "name": "SUN Tao",
                "org": "The Public Health College of Ha'erbin medica l university,Heilongjiang Ha'erbin ,China"
            },
            {
                "name": "ZHANG Jia-ying",
                "org": "China Ping'an Life Insurance Company of Heilongjiang Branch,Heilongjiang Ha'erbin ,China"
            },
            {
                "name": "SUN Quan-sheng",
                "org": "The Public Health College of Ha'erbin medica l university,Heilongjiang Ha'erbin ,China"
            },
            {
                "name": "ZHANG Fan",
                "org": "The medical insurance management center of Ha'erbin,Heilongjiang Ha'erbin ,China"
            },
            {
                "name": "LIN Hai-feng",
                "org": "Bureau of social medical insurance in Heilongjiang province,Heilongjiang Ha'erbin ,China"
            },
            {
                "name": "LI Heng",
                "org": "The Public Health College of Ha'erbin medica l university,Heilongjiang Ha'erbin ,China"
            }
        ],
        "venue": "Health Economics Research",
        "year": 2009
    },
    "3D9P5Lcl": {
        "id": "3D9P5Lcl",
        "title": "Three dimensional multi-molecule tracking in thick samples with extended depth-of-field.",
        "abstract": "We present a non-z-scanning multi-molecule tracking system with nano-resolution in all three dimensions and extended depth of field (DOF), which based on distorted grating (DG) and double-helix point spread function (DH-PSF) combination microscopy (DDCM). The critical component in DDCM is a custom designed composite phase mask (PM) combining the functions of DG and DH-PSF. The localization precision and the effective DOF of the home-built DDCM system based on the designed PM were tested. Our experimental results show that the three-dimensional (3D) localization precision for the three diffraction orders of the grating are \u03c3(-1st)(x, y, z) = (6.5 nm, 9.2nm, 23.4 nm), \u03c3(0th)(x, y, z) = (3.7 nm, 2.8nm, 10.3 nm), and \u03c3(+1s)(x, y, z) = (5.8 nm, 6.9 nm, 18.4 nm), respectively. Furthermore, the total effective DOF of the DDCM system is extended to 14 \u03bcm. Tracking experiment demonstrated that beads separated over 12 \u03bcm along the axial direction at some instants can be localized and tracked successfully.",
        "keywords": [
            "SINGLE-PARTICLE TRACKING",
            "OPTICAL RECONSTRUCTION MICROSCOPY",
            "POINT-SPREAD FUNCTION",
            "PLANE MICROSCOPY",
            "SUPERRESOLUTION MICROSCOPY",
            "DIFFRACTION-LIMIT",
            "POLYMER DOTS",
            "LOCALIZATION",
            "CELLS",
            "ACCURACY"
        ],
        "authors": [
            {
                "name": "Li Heng",
                "org": ""
            },
            {
                "name": "Chen Danni",
                "org": ""
            },
            {
                "name": "Xu Gaixia",
                "org": ""
            },
            {
                "name": "Yu Bin",
                "org": ""
            },
            {
                "name": "Niu Hanben",
                "org": ""
            }
        ],
        "venue": "Optics express",
        "year": 2015
    },
    "y4BetFxJ": {
        "id": "y4BetFxJ",
        "title": "Time-domain fluorescence lifetime measurement and analysis using a streak camera",
        "abstract": "A method which describes the impulse response function of the fluorescence lifetime measurement system that based on a streak camera using Gaussian function is presented, and a mathematical model which is used to fit the fluorescence decay curves in time-domain is established. The data of the impulse response function of the time-domain fluorescence lifetime measurement system built using the Gaussian function are fit. The goodness of the fitting is greater than 0.995. The fluorescence lifetime of the standard fluorescent dye Rose Bengal is measured and the data using the mathematical model are fit. The average goodness of fitting is greater than 0.996 and the standard deviation of lifetime is only 1.7 ps. Experimental results show that the mathematical model is reliable and accurate in processing the time-domain signal obtained by fluorescence lifetime measurement system that is based on a streak camera. The method presented simplifies the deconvolution calculation, improves the precision of lifetime measurement and can be used to process time-domain signals obtained by other systems.",
        "keywords": [
            "Data-fitting",
            "Fluorescence lifetime",
            "Least-square method",
            "Measurement",
            "Streak camera"
        ],
        "authors": [
            {
                "name": "Yan, Wang",
                "org": "Shenzhen University(Shenzhen University),Qingshuihe, Shenzhen,China"
            },
            {
                "name": "Heng Li",
                "org": "Shenzhen University(Shenzhen University),Qingshuihe, Shenzhen,China"
            },
            {
                "name": "Jing Qi",
                "org": "Shenzhen University(Shenzhen University),Qingshuihe, Shenzhen,China"
            },
            {
                "name": "Yonghong Shao",
                "org": "Shenzhen University(Shenzhen University),Qingshuihe, Shenzhen,China"
            },
            {
                "name": "Junle Qu",
                "org": "Shenzhen University(Shenzhen University),Qingshuihe, Shenzhen,China"
            },
            {
                "name": "Hanben Niu",
                "org": "Shenzhen University(Shenzhen University),Qingshuihe, Shenzhen,China"
            }
        ],
        "venue": "Zhongguo Jiguang/Chinese Journal of Lasers",
        "year": 2011
    },
    "EnZdU6Qj": {
        "id": "EnZdU6Qj",
        "title": "Super-diffraction imaging in three-dimensional localization precision of the double-helix point spread function",
        "abstract": "The combination of switch effect and single molecule positioning can realize the sample super diffraction resolution imaging, and double helix point spread function will be a single molecular orientation nanometer resolution extending from two dimensions to three dimensions. In this paper, three-dimensional (3D) positioning accuracy of the double helix point spread function is discussed. First, the theoretical localization accuracy for an unbiased estimator of the double-helix point spread function is compared with that for 3D localization using Fisher information and the influences of localization accuracy including photon number, varying levels of background and pixel size are analyzed. Second, based on the localization algorithm of gaussian fitting, which is usually adopted in data analysis of single molecular orientation in the experimental process, the axial localization accuracy of double helix point spread function is obtained by the error transfer function law. Computer simulation results show that under the condition of more than 1000 photons in number, the positioning accuracy of gaussian fitting localization algorithm and theory localization accuracy of Fisher information are in good agreement. The discussion of the paper provides not only the theoretical basis for 3D positioning accuracy of double helix point spread function, but also the theoretical guidance for the experiment at the same time.",
        "keywords": [
            "localization precision",
            "gaussian fitting",
            "double helix point spread function",
            "Fisher information"
        ],
        "authors": [
            {
                "name": "Chen He",
                "org": "  Optoelectronic Devices and Systems Ministry of Education/Guangdong Key Laboratory, College of Optoelectronic Engineering, Shenzhen University, Shenzhen , China"
            },
            {
                "name": "Yu Bin",
                "org": "  Optoelectronic Devices and Systems Ministry of Education/Guangdong Key Laboratory, College of Optoelectronic Engineering, Shenzhen University, Shenzhen , China"
            },
            {
                "name": "Chen Dan-Ni",
                "org": "  Optoelectronic Devices and Systems Ministry of Education/Guangdong Key Laboratory, College of Optoelectronic Engineering, Shenzhen University, Shenzhen , China"
            },
            {
                "name": "Li Heng",
                "org": "  Optoelectronic Devices and Systems Ministry of Education/Guangdong Key Laboratory, College of Optoelectronic Engineering, Shenzhen University, Shenzhen , China"
            },
            {
                "name": "Niu Han-Ben",
                "org": "  Optoelectronic Devices and Systems Ministry of Education/Guangdong Key Laboratory, College of Optoelectronic Engineering, Shenzhen University, Shenzhen , China"
            }
        ],
        "venue": "Acta Physica Sinica",
        "year": 2013
    },
    "ovG5Ie2n": {
        "id": "ovG5Ie2n",
        "title": "Design and experimental demonstration of high-efficiency double-helix point spread function phase plate",
        "abstract": "Double helix point spread function possesses continuously rotating invariant features with defocus,and it can be used for performing nano-resolution image of thick samples and for studying singleparticle tracking by combining the single-molecule localization method.However,the inadequacy of the original double helix point spread function is that the transfer function efficiency is very low,so it is difficult to achieve photon limited applications for the bio-imaging.The double-helix point spread function is optimized by introducing an iterative algorithm so that the constraints of the point spread function can be optimized best in three different domains:the Laguerre-Gauss modal plane,the spatial domain,and the Fourier domain.The simulation results show that the peak intensity of high efficiency double helix point spread function is 30 times higher than the original one.The design and fabrication of the phase plate are also proposed.The experimental results are in good agreement with the theoretical predictions,thus proving the feasibility of this method.",
        "keywords": [
            "super-resolution imaging",
            "optimization algorithm",
            "axial localization",
            "double helix point spread function"
        ],
        "authors": [
            {
                "name": "Li Heng",
                "org": "Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province,College of Optoelectronic Engineering,Shenzhen University,Shenzhen ,China"
            },
            {
                "name": "Yu Bin",
                "org": "Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province,College of Optoelectronic Engineering,Shenzhen University,Shenzhen ,China"
            },
            {
                "name": "Chen Dan-Ni",
                "org": "Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province,College of Optoelectronic Engineering,Shenzhen University,Shenzhen ,China"
            },
            {
                "name": "Niu Han-Ben",
                "org": "Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province,College of Optoelectronic Engineering,Shenzhen University,Shenzhen ,China"
            }
        ],
        "venue": "Acta Physica Sinica",
        "year": 2013
    },
    "lbniGwso": {
        "id": "lbniGwso",
        "title": "A miniature laser speckle fluorescence sectioning microscope for cell imaging",
        "abstract": "We present a miniature fluorescence sectioning microscope which uses a diode-pumped solid-state (DPSS) laser as the light source and a fast translating diffuser to produce dynamically changing speckle patterns onto the back aperture of the objective to illuminate the sample. Optical sectioning, which originates from the statistical characteristics of laser speckles, is obtained by calculating the contrast of a series of fluorescence images. High contrast fluorescence sectioning images of bovine pulmonary artery endothelial (BPAE) cells are obtained. The image quality is similar to that of the images acquired by standard laser scanning confocal microscope (LSCM). Compared with LSCM, the laser speckle fluorescence microscope (LSFM) presented in this letter has many advantages, such as simple configurations, low cost, compact, and easy to operate, which makes it possible to have wide spread applications in biomedicine.",
        "keywords": [
            "confocal microscopy",
            "fluorescence microscopy"
        ],
        "authors": [
            {
                "name": "Yonghong Shao",
                "org": " Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, Institute of Optoelectronics, Shenzhen University, Shenzhen , China"
            },
            {
                "name": "Heng Li",
                "org": " Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, Institute of Optoelectronics, Shenzhen University, Shenzhen , China"
            },
            {
                "name": "Qiao Wen",
                "org": " Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, Institute of Optoelectronics, Shenzhen University, Shenzhen , China"
            },
            {
                "name": "Yan Wang",
                "org": " Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, Institute of Optoelectronics, Shenzhen University, Shenzhen , China"
            },
            {
                "name": "Junle Qu",
                "org": " Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, Institute of Optoelectronics, Shenzhen University, Shenzhen , China"
            },
            {
                "name": "Hanben Niu",
                "org": " Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, Institute of Optoelectronics, Shenzhen University, Shenzhen , China"
            }
        ],
        "venue": "\u4e2d\u56fd\u5149\u5b66\u5feb\u62a5(\u82f1\u6587\u7248)",
        "year": 2010
    },
    "gWEelgZY": {
        "id": "gWEelgZY",
        "title": "Design, fabrication, and experimental demonstration of a diffractive optical element with long depth of field for nanoscale three-dimensional multi-molecule tracking",
        "abstract": "The development of real-time single-molecule detection and tracking technology in time and space for multiple bio-molecules in intact cells has important significance for the study on molecular behaviors in life processes. However, limited depth of field is the main drawback of conventional microscopy that prevents observation and tracking of multiple molecules in intact cells. Based on the principle of wavefront coding, the design and fabrication of a novel diffractive optical element (DOE) which combines a distorted diffraction grating with a double-helix point spread function (PSF) phase plate so that it can simultaneously perform multi-plane imaging with double-helix PSF and realize an extended depth of field is presented. Experiments have been carried out on a self-built microscopic system based on the novel DOE, showing that a depth of field can be up to 12 \u03bcm. Experimental results are in good agreement with the theoretical predictions, thus proving the feasibility of this method.",
        "keywords": [
            "distorted diffraction grating",
            "double helix point spread function",
            "multi-molecule tracking",
            "diffractive optical element"
        ],
        "authors": [
            {
                "name": "Yu Bin",
                "org": " Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province , College of Optoelectronic Engineering, Shenzhen University, Shenzhen , China "
            },
            {
                "name": "Li Heng",
                "org": " Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province , College of Optoelectronic Engineering, Shenzhen University, Shenzhen , China "
            },
            {
                "name": "Chen Dan-Ni",
                "org": " Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province , College of Optoelectronic Engineering, Shenzhen University, Shenzhen , China "
            },
            {
                "name": "Niu Han-Ben",
                "org": " Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province , College of Optoelectronic Engineering, Shenzhen University, Shenzhen , China "
            }
        ],
        "venue": "Acta Physica Sinica",
        "year": 2013
    },
    "8nVUu5CK": {
        "id": "8nVUu5CK",
        "title": "Improving the precision of fluorescence lifetime measurement using a streak camera",
        "abstract": "Streak camera has high temporal resolution and high sensitivity, and is a powerful tool in biomedical study to measure fluorescence lifetime and perform fluorescence lifetime imaging. However, nonuniformity of the gain in the streak tube and nonlinearity of the sweeping speed limit the precision of fluorescence lifetime measurement, particularly when fluorescence lifetimes are short. We have constructed a two-photon excitation fluorescence lifetime measurement system that is based on a synchroscan streak camera and have developed accordingly a method to correct the effect of gain nonuniformity and nonlinearity of sweeping speed on the measurement precision. A continuous-wave laser of high stability is used to calibrate the gain of the streak camera, and a Fabry-Perot etalon is used to calibrate the nonlinearity of the sweeping speed. Fitting algorithms are used to correct the gain of the streak camera and nonlinearity of the sweeping speed respectively, which significantly improves the measurement precision of the system, as characterized through the fluorescence lifetime of the short-lived fluorescence dye, Rose Bengal. Experimental results show that the measurement fluctuation of the lifetime has been improved from more than 10% to 2% after correcting the effects of gain nonuniformity and sweeping speed nonlinearity.",
        "keywords": [
            "microscopy"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": " Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, Institute of Optoelectronics, Shenzhen University, Shenzhen , China"
            },
            {
                "name": "Yonghong Shao",
                "org": " Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, Institute of Optoelectronics, Shenzhen University, Shenzhen , China"
            },
            {
                "name": "Yan Wang",
                "org": " Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, Institute of Optoelectronics, Shenzhen University, Shenzhen , China"
            },
            {
                "name": "Junle Qu",
                "org": " Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, Institute of Optoelectronics, Shenzhen University, Shenzhen , China"
            },
            {
                "name": "Hanben Niu",
                "org": " Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, Institute of Optoelectronics, Shenzhen University, Shenzhen , China"
            }
        ],
        "venue": "\u4e2d\u56fd\u5149\u5b66\u5feb\u62a5(\u82f1\u6587\u7248)",
        "year": 2010
    },
    "O1qIWHl3": {
        "id": "O1qIWHl3",
        "title": "A fluorescence lifetime spectrometer based on a synchroscan streak camera",
        "abstract": "A two-photon excitation fluorescence lifetime spectrometer based on a synchroscan streak camera was presented.The spectrometer was calibrated using a Titanium:Sapphire femtosecond laser in conjunction with a custom-made synchronized streak circuit,tunable delay generator and a set of etalons.Experimental results show that the temporal resolution of this spectrometer is 9 ps,nonlinearity is less than 4%,and the sweep range is 2.8 ns.Fluorescence decay profile of fluorescent dye Rose Bengal(RsB) is recorded with the spectrometer.Nonlinear least square fitting of the decay profile gives that the lifetime of RsB is 763 ps,consistent with standard fluorescence dyes.",
        "keywords": [
            "temporal resolution",
            "fluorescence microscopy",
            "two-photon excitation",
            "fluorescence lifetime",
            "sweep speed",
            "synchroscan streak camera"
        ],
        "authors": [
            {
                "name": "SHAO Yong-hong",
                "org": "College of Optoelectronic Engineering Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education,Key Laborotory of Optoelectronics Devices and Systems of Guangdong Province,Shenzhen University Shenzhen  P.R.China"
            },
            {
                "name": "LI Heng",
                "org": "College of Optoelectronic Engineering Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education,Key Laborotory of Optoelectronics Devices and Systems of Guangdong Province,Shenzhen University Shenzhen  P.R.China;College of Opt-electro Engineering Xi'an Technological University Xi'an  P.R.China"
            },
            {
                "name": "WANG Yan",
                "org": "College of Optoelectronic Engineering Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education,Key Laborotory of Optoelectronics Devices and Systems of Guangdong Province,Shenzhen University Shenzhen  P.R.China"
            },
            {
                "name": "QU Jun-le",
                "org": "College of Optoelectronic Engineering Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education,Key Laborotory of Optoelectronics Devices and Systems of Guangdong Province,Shenzhen University Shenzhen  P.R.China"
            },
            {
                "name": "Hanben NIU",
                "org": "College of Optoelectronic Engineering Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education,Key Laborotory of Optoelectronics Devices and Systems of Guangdong Province,Shenzhen University Shenzhen  P.R.China"
            }
        ],
        "venue": "Journal of Shenzhen University Science and Engineering",
        "year": 2009
    },
    "N4VSZ8BE": {
        "id": "N4VSZ8BE",
        "title": "A fluorescence lifetime spectrometer based on a synchroscan streak camera",
        "abstract": "A two-photon excitation fluorescence lifetime spectrometer based on a synchroscan streak camera was presented. The spectrometer was calibrated using a Titanium: Sapphire femtosecond laser in conjunction with a custom-made synchronized streak circuit, tunable delay generator and a set of etalons. Experimental results show that the temporal resolution of this spectrometer is 9 ps, nonlinearity is less than 4%, and the sweep range is 2.8 ns. Fluorescence decay profile of fluorescent dye Rose Bengal (RsB) is recorded with the spectrometer. Nonlinear least square fitting of the decay profile gives that the lifetime of RsB is 763 ps, consistent with standard fluorescence dyes.",
        "keywords": [
            "Fluorescence lifetime",
            "Fluorescence microscopy",
            "Sweep speed",
            "Synchroscan streak camera",
            "Temporal resolution",
            "Two-photon excitation"
        ],
        "authors": [
            {
                "name": "Yonghong Shao",
                "org": "Shenzhen University(Shenzhen University),Qingshuihe, Shenzhen,China"
            },
            {
                "name": "Heng Li",
                "org": "Shenzhen University(Shenzhen University),Qingshuihe, Shenzhen,China"
            },
            {
                "name": "Yan, Wang",
                "org": "Shenzhen University(Shenzhen University),Qingshuihe, Shenzhen,China"
            },
            {
                "name": "Junle Qu",
                "org": "Shenzhen University(Shenzhen University),Qingshuihe, Shenzhen,China"
            },
            {
                "name": "Hanben Niu",
                "org": "Shenzhen University(Shenzhen University),Qingshuihe, Shenzhen,China"
            }
        ],
        "venue": "Shenzhen Daxue Xuebao (Ligong Ban)/Journal of Shenzhen University Science and Engineering",
        "year": 2009
    },
    "lyW3UTB0": {
        "id": "lyW3UTB0",
        "title": "Approach to multiparticle parallel tracking in thick samples with three-dimensional nanoresolution.",
        "abstract": "This Letter proposes a method referred to as distorted grating (DG) and double-helix point spread function (DH-PSF) combination microscopy (DDCM), which is capable of multiparticle parallel localization and tracking in a transparent sample thicker than 10 \u03bcm, the thickness of cells. A special phase mask, combining the field depth extension capabilities of DG with the three-dimensional (3D) nanolocalization capabilities of the DH-PSF, is designed for multiparticle parallel localization. Time-lapse tracking of one particle moving along the z axis and parallel tracking of two particles are simulated. Results demonstrate that, with only a single snapshot, particles can be localized, tracking with 3D nanoresolution wherever they are. The theoretical localization precisions of DDCM, DH-PSF, and multifocus microscopy are compared. DDCM results in almost constant localization precisions in all three dimensions for a depth of field larger than 10 \u03bcm. DDCM is expected to become a tool in investigations of important dynamic events in living cells.",
        "keywords": [
            "OPTICAL RECONSTRUCTION MICROSCOPY",
            "MULTIFOCAL PLANE MICROSCOPY",
            "POINT-SPREAD FUNCTION",
            "FLUORESCENCE MICROSCOPY",
            "LOCALIZATION ACCURACY",
            "DIFFRACTION-LIMIT",
            "CELLULAR-DYNAMICS",
            "FOCAL PLANES",
            "3D"
        ],
        "authors": [
            {
                "name": "Chen Danni",
                "org": ""
            },
            {
                "name": "Yu Bin",
                "org": ""
            },
            {
                "name": "Li Heng",
                "org": ""
            },
            {
                "name": "Huo Yingdong",
                "org": ""
            },
            {
                "name": "Cao Bo",
                "org": ""
            },
            {
                "name": "Xu Gaixia",
                "org": ""
            },
            {
                "name": "Niu Hanben",
                "org": ""
            }
        ],
        "venue": "Optics letters",
        "year": 2013
    },
    "xAihLlPY": {
        "id": "xAihLlPY",
        "title": "Spectrally resolved multifocal multiphoton microscopy using microlens array and galvo mirror scanning",
        "abstract": "We present a novel spectrum-resolved multifocal multiphoton microscopy (SR-MMM) that is capable of performing fast 2-dimensional (2D) spectral measurements of fluorescent samples with optical sectioning. Fluorescence emission from the excited lines on the sample is spectrally dispersed with a prism, and a CCD array is used to acquire the spectrally resolved image. Spectrally resolved images of 512 pixel \u00d7 512 pixel can be obtained by acquiring only 128 raw images when a 4 \u00d7 4 excitation foci array is used. Multi-color fluoresent beads, sample slide of a stained lily and pollen particles are used for spectrally resolved imaging experiment. The spectral measurement range is from 450 nm to 700 nm, and the spectral resolution is less than 3 nm.",
        "keywords": [
            "Biophotonics",
            "Fluorescence microscopy",
            "Fluorescence spectroscopy",
            "Multifocal multiphoton microscopy",
            "Multiphoton excitation"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": "Xi'an University of Technology(Xi'an University of Technology,Xi'an Univ. of Technol.),Xi An,China"
            },
            {
                "name": "Yonghong Shao",
                "org": "Shenzhen University(Shenzhen University),Qingshuihe, Shenzhen,China"
            },
            {
                "name": "Yan, Wang",
                "org": "Shenzhen University(Shenzhen University),Qingshuihe, Shenzhen,China"
            },
            {
                "name": "Junle Qu",
                "org": "Shenzhen University(Shenzhen University),Qingshuihe, Shenzhen,China"
            },
            {
                "name": "Ying An",
                "org": "Xi'an University of Technology(Xi'an University of Technology,Xi'an Univ. of Technol.),Xi An,China"
            },
            {
                "name": "Hanben Niu",
                "org": "Shenzhen University(Shenzhen University),Qingshuihe, Shenzhen,China"
            }
        ],
        "venue": "Zhongguo Jiguang/Chinese Journal of Lasers",
        "year": 2010
    },
    "uLEkqWzp": {
        "id": "uLEkqWzp",
        "title": "Effect of Loading Infusion with Hydroxyethyl Starch 200/0.5 or 130/0.4 Solution on Platelet Activity in Patients with Coronary Heart Disease During Perioperative Period",
        "abstract": "[Objective] To investigate the effect of loading infusion with hydroxyethyl starch 200/0.5 or 130/0.4 solution on platelet activity in the patients with coronary heart disease (CHD) during perioperative period. [Methods] Forty-five patients with coronary heart disease who received cholecystectomy were randomly and equally assigned into 3 groups: hydroxyethyl starch HES200/0.5 solution group (group\u2160), HES130/0.4 solution group (group\u2161) and lactated Ringers' (RL) solution group (group \u2162, as control group). HES200/0.5 solution, HES130/0.4 solution, or RL solution were respectively infused at a dose of 10 mL.kg-1 over a period of 30 min before surgery. Flow cytometry was used to measure the expression of GPIIb/IIIa and GMP-140 before infusion (T0), at the end of infusion (T1), at 1 h after infusion (T2) and at 2 h after surgery end (T3). [Results] The expression of GP\u2161b/\u2162a and GMP-140 in group\u2160 was decreased significantly after infusion as compared to the baseline values at T0(P < 0.05). The expression of GP\u2161b/\u2162a in group \u2161 was decreased significantly after infusion as compared to that at T0 (P < 0.05); Compared with group \u2161and group \u2162, the expression of GP\u2161b/\u2162a and GMP-140 after infusion was significantly lower (P < 0.05) in group \u2160. Compared with group \u2162, the expression of GP\u2161b/\u2162a and GMP-140 after infusion was significantly lower in group \u2161 (P < 0.05). The expression of GMP-140 was increased significantly at T2 and T3 than that at T0 in group \u2162 (P < 0.05). [Conclusion] Infusion with HES solution can inhibit excessive activation of platelet in the patients with coronary heart disease during perioperative period and HES200/0.5 had the stronger effect than that of HES130/0.4, which may prevent aggravation of the disease and ameliorate prognosis.",
        "keywords": [
            "platelet membrane glycoprotein",
            "coronary heart disease",
            "hydroxyethyl starch"
        ],
        "authors": [
            {
                "name": "LIANG Hua",
                "org": " Department of Anesthesiology, The Affiliated Foshan Hospital, SUN Yat-sen University, Foshan , China "
            },
            {
                "name": "HUANG Qiong",
                "org": " Department of Anesthesiology, The Affiliated Foshan Hospital, SUN Yat-sen University, Foshan , China "
            },
            {
                "name": "WEN Xian-jie",
                "org": " Department of Anesthesiology, The Affiliated Foshan Hospital, SUN Yat-sen University, Foshan , China "
            },
            {
                "name": "ZHANG Ya-jun",
                "org": " Department of Anesthesiology, The Affiliated Foshan Hospital, SUN Yat-sen University, Foshan , China "
            },
            {
                "name": "LI Heng",
                "org": " Department of Anesthesiology, The Affiliated Foshan Hospital, SUN Yat-sen University, Foshan , China "
            },
            {
                "name": "LIU Hong-zhen",
                "org": " Department of Anesthesiology, The Affiliated Foshan Hospital, SUN Yat-sen University, Foshan , China "
            },
            {
                "name": "YANG Cheng-xiang",
                "org": " Department of Anesthesiology, The Affiliated Foshan Hospital, SUN Yat-sen University, Foshan , China "
            }
        ],
        "venue": "Journal of Sun Yat-Sen University(Medical Sciences)",
        "year": 2008
    },
    "4L01l8DA": {
        "id": "4L01l8DA",
        "title": "Propofol combined with remifentanil target-controlled infusion used in fiberoptic bronchoscope examination",
        "abstract": "[Objective] To observe the clinic effect of blood target-controlled infusion(TCI) with propoful and remifentanil for fiberoptic bronchoscope examination. [Methods] Ninety-six patients undergoing fiberoptic bronchoscopy were randomly divided into two groups: TCI group and constant infusion group. [Result] The anesthesia effect of two groups was of no significant difference. But the time of induction, the recovery time and the time of leaving the hospital were shorter in the TCI group (P <0.05). MAP and HR were more stable in TCI group. [Conclusion] Blood target-controlled infusion of propofol and remifentanil is safe and effective. It has the advantages of good control, less hemodynamic effect and patients can recover earlier and go home earlier.",
        "keywords": [
            "TCI",
            "fiberoptic bronchoscope",
            "propofol",
            "remifentanil"
        ],
        "authors": [
            {
                "name": "GAO Run-xing",
                "org": "Department of Anesthesiology, the First Hospital of Foshan, Foshan, Guangdong , P.R.China"
            },
            {
                "name": "YANG Cheng-xiang",
                "org": "Department of Anesthesiology, the First Hospital of Foshan, Foshan, Guangdong , P.R.China"
            },
            {
                "name": "LI Heng",
                "org": "Department of Anesthesiology, the First Hospital of Foshan, Foshan, Guangdong , P.R.China"
            }
        ],
        "venue": "China Journal of Endoscopy",
        "year": 2008
    },
    "77wPVh8D": {
        "id": "77wPVh8D",
        "title": "Application of Remifentanil by TCI without relaxant for tracheal intubation in pediatric patients",
        "abstract": "[Objective] To observe the tracheal intubation conditions hemodynamic changes during Remifentanil target controlled infusion(TCI) at different plasma concentrations combined with Propofol. [Methods] Forty-five pediatric patients were randomly allocated into three groups. Remifentanil were given using TCI at plasma concentration of 2 ng/mL,3 ng/mL and 4 ng/mL in each group respectively and after 5-min Remifentanil infusion, Propofol was given with TCI at plasma concentration 2.5 \u03bcg/mL. Ten minutes later, inserting laryngoscope and tracheal intubation were teied and intubation conditions were recorded. If failed, the Remifentanil concentration was tried ten minutes later. The heart rate and blood pressure at baseline, after Remifentanil infusion, before intubation and one minute after intubation were recorded.Meanwhile, the intubation scores and side effects during induction were recorded.",
        "keywords": [
            "Remifentanil",
            "small children",
            "Propofol",
            "tracheal intubation"
        ],
        "authors": [
            {
                "name": "GAO Run-xing",
                "org": "Department of Anesthesiology, the First Hospital of Foshan, Foshan, Guangdong , P.R.China"
            },
            {
                "name": "ZHOU Jun",
                "org": "Department of Anesthesiology, the First Hospital of Foshan, Foshan, Guangdong , P.R.China"
            },
            {
                "name": "LI Heng",
                "org": "Department of Anesthesiology, the First Hospital of Foshan, Foshan, Guangdong , P.R.China"
            },
            {
                "name": "YANG Cheng-xiang",
                "org": "Department of Anesthesiology, the First Hospital of Foshan, Foshan, Guangdong , P.R.China"
            }
        ],
        "venue": "China Journal of Modern Medicine",
        "year": 2008
    },
    "nwCEXkTk": {
        "id": "nwCEXkTk",
        "title": "Effects of volatile anesthetics on rat heart ischemia-reperfusion injury in vitro",
        "abstract": "AIM: To investigate the effect of volatile anesthetics on function,metabolism,ATPase activity and free radicals in isolated ischemia /reperfusion(I/R) rat hearts.METHODS: 136 SD rats were anesthetized with pentobarbital and randomly divided into six groups and 17 sub-groups(n=8),according to the given drug.In a normal thermal isolated Langendorff rat heart model,four volatile anesthetics in 1.5 MAC concentration were given before global ischemia 25 min and during reperfusion 30 min.Coronary flow(CF),LVEDP,left ventricular developed pressure(LVDP),\u00b1dp/dt were monitored at 15 min of equilibrium,15 min of drug treatment,the end of reperfusion.Myocardial adenosine triphosphate(ATP),malodialdehyde(MDA),activity of Ca2+-ATPase and Na+-K+-ATPase,and superoxide dismutase(SOD) were determined at 15 min of equilibrium,15 min of drug treatment or absence,10 min global ischemia and the end of reperfusion.RESULTS: CF and LVEDP were iocreased significantly after exposured to volatile anesthetics 15 min,and LVDP,+dp/dtmax were significantly decreased.However,LVDP and +dp/dtmax were increased at the end of reperfusion in the treated groups.HR in halothane and isoflurane groups was decreased before ischemia and after reperfusion.The myocardial ATP content was significantly increased before and after ischemia in the treated groups.At the end of reperfusion,the activity of SOD was significantly higher and myocardial MDA content was significantly lower in the treated groups than those in control group.The activity of Ca2+-ATPase,compared with the control group,was markedly decreased before ischemia in halothane,enflurane and isoflurane group.Nonetheless,the activity of Ca2+-ATPase was clearly increased in the treated groups during ischemia and at the end of reperfusion.The activity of Na+-K+-ATPase was only enhanced in halothane group at the end of reperfusion among groups.CONCLUSION: The volatile anesthetics depress myocardial systolic function.There are markedly protective effects against myocardial I/R injury.Meanwhile,the volatile anesthetics improve the recovery of function and metabolism,and increase CF and the activity of Ca2+-ATPase and Na+-K+-ATPase in rats.",
        "keywords": [
            "Enflurane",
            "Heart function tests",
            "Isoflurane",
            "Halothane",
            "Myocardial reperfusion injury",
            "Sevoflurane"
        ],
        "authors": [
            {
                "name": "LI Heng",
                "org": " Department of Anesthesiology,Affiliated Foshan Hospital of Sun Yat-sen University,Foshan ,China"
            },
            {
                "name": "YANG Cheng-xiang",
                "org": " Department of Anesthesiology,Affiliated Foshan Hospital of Sun Yat-sen University,Foshan ,China"
            },
            {
                "name": "SUN Kai",
                "org": " Department of Anesthesiology,Affiliated Foshan Hospital of Sun Yat-sen University,Foshan ,China"
            },
            {
                "name": "MENG Xian-hui",
                "org": " Department of Anesthesiology,The Henan Provincial Chest Hospital,Zhengzhou ,China"
            },
            {
                "name": "DONG Xiao-li",
                "org": " Department of Anesthesiology,The Henan Provincial Chest Hospital,Zhengzhou ,China"
            },
            {
                "name": "ZENG Yin-ming",
                "org": " Jiangsu Province Key Laboratory of Anesthesiology,Xuzhou ,China."
            },
            {
                "name": "WANG Jun",
                "org": " Jiangsu Province Key Laboratory of Anesthesiology,Xuzhou ,China."
            }
        ],
        "venue": "Chinese Journal of Pathophysiology",
        "year": 2007
    },
    "8fzY6ucl": {
        "id": "8fzY6ucl",
        "title": "THE EXPRESSION OF nNOS ON THE SPINAL CORD OF THE RATS FOLLOWING CHRONIC CONSTRICTION INJURY OF THE SCIATIC NERVE",
        "abstract": "Objective:To investigate the expression of nitric oxide synthase(nNOS) on the spinal cord of the rats following chronic constriction injury(CCI) of the sciatic nerve.Methods:Forty male Sprague-Dawley rats weighting 200\uff5e220 g were randomly divided into five groups(n=8):naive group;sham operation group;CCI 5 d group;CCI 10 d group;CCI 15 d group.The mechanical withdrawal threshold(MWT) and thermal withdrawal latency(TWL) of rats in each group were measured by Von Frey hair and radiant thermal stimulator respectively.The expression of nNOS on the spinal cord of the rats in each group was detected with immunohistochemical staining at the 5th d,10th d,15th d after operation,and the number of the nNOS positive neurons was counted under microscope.Results:MWT and TWL of the rats in CCI 5d group;CCI 10d group;CCI 15d group were decreased significantly compared to the rats in naive group and sham group.The expression of nNOS on the spinal cord of the rats in CCI groups was markedly increased compared with naive group and sham group.Conclusion:These data shows that nNOS-positive neurons increase on the spinal cord of the rats following chronic constriction of sciatic nerve,the nNOS in the spinal cord possibly involves in the CCI-induced mechanical and thermal hyperalgesia.",
        "keywords": [
            "Neuropathic pain",
            "Spinal cord",
            "nNOS",
            "Immunohistochemistry"
        ],
        "authors": [
            {
                "name": "WEN Xian-Jie",
                "org": "Department of Anesthesiology,The First People's Hospital of Foshan & Affiliated Foshan Hospital of Sun Yat-Sen University,Foshan,"
            },
            {
                "name": "LI Heng",
                "org": "Department of Anesthesiology,The First People's Hospital of Foshan & Affiliated Foshan Hospital of Sun Yat-Sen University,Foshan,"
            },
            {
                "name": "ZENG Yin-Ming",
                "org": "Department of Anesthesiology,The First People's Hospital of Foshan & Affiliated Foshan Hospital of Sun Yat-Sen University,Foshan,"
            },
            {
                "name": "FANG Zhi-Yuan",
                "org": "Department of Anesthesiology,The First People's Hospital of Foshan & Affiliated Foshan Hospital of Sun Yat-Sen University,Foshan,"
            },
            {
                "name": "LIANG Hua",
                "org": "Department of Anesthesiology,The First People's Hospital of Foshan & Affiliated Foshan Hospital of Sun Yat-Sen University,Foshan,"
            },
            {
                "name": "LI Zhang-Jun",
                "org": "Department of Anesthesiology,The First People's Hospital of Foshan & Affiliated Foshan Hospital of Sun Yat-Sen University,Foshan,"
            }
        ],
        "venue": "Chinese Journal of Pain Medicine",
        "year": 2008
    },
    "CRCvL2Va": {
        "id": "CRCvL2Va",
        "title": "The Effect of Preoperative Infusion with Hydroxyethyl Starch 130/0.4 Solution on Hemorheological Parameters of Colon Cancer Patients during Perioperative Period and Postoperative Deep Venous Thrombosis",
        "abstract": "Objective To investigate the effect of acute hypervolemic hemodilution (AHHD) with hydroxyethyl starch (HES) 130/0.4 solution before surgery on hemorheological parameters of patients with colon cancer during perioprative period. Methods Forty patients undergoing colon cancer radical surgery were randomly divided into 2 groups (n = 20 each): HES 130/0.4 solution group (HES group ) and Ringer's Lactated solution group (RL group ). The two kinds of solution were respectively infused at a dose of 15 ml.kg-1 over a period of 30min before surgery. Blood samples were taken for determination of hemorheology variables before AHHD (T0, baseline), at the end of AHHD (T1), 1 h after the end of AHHD (T2) and 1 h after the end of surgery (T3). DVT was diagnosed by color Doppler ultrasonic system. Results The blood viscosity, plasma viscosity, erythrocyte aggregation index (EAI), fibrinogen and HCT were decreased significantly as compared with the baseline values at T0 in HES group(P < 0.05). The blood viscosity at low shear rate and EAI at T3 were increased significantly as compared with the baseline values at T0 in RL group (P < 0.05). The blood viscosity, plasma viscosity, EAI, fibrinogen and HCT in HES group were lower than those in RL group at T2 and T3 (P < 0.05) . Compared with RL group,the postoperative DVT occurrence significantly decreased in HES group (P < 0.05). Conclusion Loading infusion with HES 130/0.4 solution can ameliorate hemorheology variables in patients with colon cancer during perioperative period and decrease the postoperative DVT occurrence.",
        "keywords": [
            "Colonic neoplasm",
            "Hydroxyethyl starch",
            "Fluid therapy",
            "Hemorheology"
        ],
        "authors": [
            {
                "name": "LIANG Hua",
                "org": " ,TAN Yong-zhao. Department of Anesthesiology, Affiliated Foshan Hospital ,SUN Yat-sen University, Foshan Guangdong , China"
            },
            {
                "name": "YANG Cheng-xiang",
                "org": " ,TAN Yong-zhao. Department of Anesthesiology, Affiliated Foshan Hospital ,SUN Yat-sen University, Foshan Guangdong , China"
            },
            {
                "name": "LI Heng",
                "org": " ,TAN Yong-zhao. Department of Anesthesiology, Affiliated Foshan Hospital ,SUN Yat-sen University, Foshan Guangdong , China"
            },
            {
                "name": "WEN Xian-jie",
                "org": " ,TAN Yong-zhao. Department of Anesthesiology, Affiliated Foshan Hospital ,SUN Yat-sen University, Foshan Guangdong , China"
            }
        ],
        "venue": "Journal of Chinese Microcirculation",
        "year": 2008
    },
    "uDsLiLZd": {
        "id": "uDsLiLZd",
        "title": "Effect of 6 % hydroxyethyl starch 130/0.4 on renal function in patients undergoing cardiac valve replacement with cardiopulmonary bypass",
        "abstract": "AIM To investigate the effect of 6 % hydroxyethyl starch 130/0.4 on renal function in patients undergoing cardiac valve replacement with cardiopulmonary bypass during perioperative period. METHODS Forty ASA\u2161or\u2162patients undergoing cardiac mitral valve replacement were randomly divided into 2 groups(n = 20 each),with 6 % hydroxyethyl starch 130/0.4 15 mL\u00b7kg~(-1)and succinylated gelatin 15 mL\u00b7kg~(-1)prefilled in extracorporeal heart-lung machine for trial group and control group,respectively.Liquid intake and output,hemodynamics,balance of electrolytes and renal function were recorded before induction of anesthesia(T_0),at the end of operation(T_1),12 h after operation(T_2),24 h after operation(T_3)and 48 h after operation(T_4).RESULTS Comparing with control group,the infusion volumes of artificial colloid were significantly lower at the first and second 12 h after operation in trial group(P<0.01)and the infusion volume of R-L was significantly lower at the second 12 h after operation in trial group(P<0.01).The urea nitrogen (BUN)and creatinine(Cr)in blood serum were significantly higher at T_3 than those at T_0,with significant difference(P<0.05)in both groups.The cystatin C in blood serum were significantly higher at T_1,T_2 and T_3 than that of T_0(P<0.05).The retinol binding protein(RBP)and\u03b22-microglobulin in urine were significantly higher at T_1 and T_2 than those at T_0,showing statistical significance(P<0.05).There was no statistical difference on renal function in all the times between the two groups(P>0.05).CONCLUSION Cardiopulmonary bypass effects renal function in patients undergoing cardiac valve replacement during the perioperation period and 6% hydroxyethyl starch 130/0.4 would not aggravate renal dysfunction.",
        "keywords": [
            "kidney function tests",
            "hetastarch",
            "cardiopulmonary bypass"
        ],
        "authors": [
            {
                "name": "ZHOU Jun",
                "org": "Department of A nesthesia,the First People's Hospital of Foshan,Foshan GUA NGDONG ,China"
            },
            {
                "name": "ZHONG Ji-ying",
                "org": "Department of A nesthesia,the First People's Hospital of Foshan,Foshan GUA NGDONG ,China"
            },
            {
                "name": "LI Heng",
                "org": "Department of A nesthesia,the First People's Hospital of Foshan,Foshan GUA NGDONG ,China"
            },
            {
                "name": "LIU Lin-sheng",
                "org": "Department of A nesthesia,the First People's Hospital of Foshan,Foshan GUA NGDONG ,China"
            },
            {
                "name": "CHEN Yue-yuan",
                "org": "Department of A nesthesia,the First People's Hospital of Foshan,Foshan GUA NGDONG ,China"
            },
            {
                "name": "YANG Cheng-xiang",
                "org": "Department of A nesthesia,the First People's Hospital of Foshan,Foshan GUA NGDONG ,China"
            }
        ],
        "venue": "Chinese Journal of New Drugs and Clinical Remedies",
        "year": 2008
    },
    "D2315p0u": {
        "id": "D2315p0u",
        "title": "Progress in research of volatile anesthetics postconditioning for ischemia-reperfusion myocardial protection",
        "abstract": "Ischemic postconditioning has been considered as a novel therapeutic approach exerting cardioprotective effects,name- ly,a episodes of brief intermittent repetitive interruption to reperfusion at onset of reperfusion after a prolonged period of iscbemia.Lots of studies had been indicated that ischemic postconditioning could generate a definite and distinguished myocardial protection.Volatile anesthetics postconditioning also can mimic ischemic postconditioning to exert the same cardioprotective effects in some trials,Howev- er,its mechanism is not completely elucidated because multiple aspects are involved in it.This review will focus on the cardioprotective mechanism of volatile anesthetics postconditioning.",
        "keywords": [
            "ischemia-repeffusion",
            "volatile anesthetics",
            "postconditioning"
        ],
        "authors": [
            {
                "name": "LI Heng",
                "org": " Department of Anesthesiology,the First People's Hospital of Foshan,Foshan ,China"
            },
            {
                "name": "ZENG Yin-ming",
                "org": ""
            }
        ],
        "venue": "International Journal of Anesthesiology and Resuscitation",
        "year": 2007
    },
    "8tfbG8h0": {
        "id": "8tfbG8h0",
        "title": "Application of target controlled infusion of propofol and remifentanil in bronchoscopy anesthesia",
        "abstract": "Objective To observe the effects of three induction modes on vital signs of patients receiving target controlled infusion of propofol and remifentanil in bronchoscopy anesthesia.Methods Sixty patients(ASA\u2160or\u2161) undergoing bronchoscopy were randomly divided into 3 induction groups: rapid mode,smooth mode or stepwise mode(n=20 for each group).Patients were induced by effect-site concentration of 6.0\u03bcg/ml propofol and 4.0 ng/ml remifentanil,followed by bronchoscope insertion and maintained anesthesia with 2.0\u03bcg/ml propofol and 2.0 ng/ml remifentanil.MAP,HR and SpO2were recorded before oxygen inhalation(T0),1 min after induction(T1),when insertion(T2),1 min after(T3),2 min after(T4),5 min after insertion(T5) and at the end of bronchoscopy(T6).Results Time for reaching target concentration and for falling asleep in the stepwise mode was longer than that in the other two modes(P< 0.01 vs.rapid mode andP< 0.05 vs.smooth mode,respectively).Patients in the stepwise mode had higher MAP at T2(P< 0.05) and less incidence of hypotension(P< 0.05) compared with the other modes.Conclusion Compared with the rapid mode and the smooth mode,patients induced by the stepwise mode are more stable in blood pressure when receiving target controlled infusion of propofol and remifentanil in bronchoscopy anesthesia although it is less controllable.",
        "keywords": [
            "Bronchoscopy",
            "Remifentanil",
            "Target controlled infusion",
            "Propofol"
        ],
        "authors": [
            {
                "name": "LIANG Xing-tian",
                "org": ",et al.Department of Anesthesiology,The First People's Hospital of Foshan,Guangdong,China"
            },
            {
                "name": "LI Heng",
                "org": ",et al.Department of Anesthesiology,The First People's Hospital of Foshan,Guangdong,China"
            },
            {
                "name": "LI Wei-min",
                "org": ",et al.Department of Anesthesiology,The First People's Hospital of Foshan,Guangdong,China"
            }
        ],
        "venue": "The Journal of Clinical Anesthesiology",
        "year": 2011
    },
    "vGFh8oUI": {
        "id": "vGFh8oUI",
        "title": "Hydroxyethyl starch 130/0.4 inhibiting nuclear factor kappa B activity of neutrophils in patients undergoing cardiac valve replacement with cardiopulmonary bypass",
        "abstract": "AIM To investigate the effects of 6%hydroxyethyl starch 130/0.4 on the nuclear factor kappa B(NF-\u03baB) activity of neutrophils in patients undergoing cardiac valve replacement with cardiopulmonary bypass(CPB).METHODS Sixty ASA\u2161or\u2162patients undergoing cardiac mitral valve replacement with CPB were randomized into 2 groups(n = 30 each).Heart-lung machine were processed with 6%hydroxyethyl starch 130/0.4(group\u2164) and succinylated gelatin(group C) 15 mL\u00b7kg~(-1),respectively.The 6%hydroxyethyl starch 130/0.4 or succinylated gelatin 10 mL\u00b7kg~(-1) was intravenously infused between the time after intubation and before CPB.Intraoperative hemodynamic changes,aortic cross-clamping time,the CPB turn around time and operation time were recorded.Neutrophiles were isolated from peripheral blood,which were collected from peripheral artery after induction of anesthesia(T_0),opening aortic cross-clamping in CPB(T_1),at the end of CPB(T_2) and at the end of operation(T_3).neutrophil cytoplasmic protein were extracted and quantitated,and the content of activation of NF-\u03baB p65,acidification of NF-\u03baB p65 and total NF-\u03baB were tested.RESULTS There were no significant differences in aortic cross-clamping time,CPB time,operation time and mean arterial pressure,heart rate,central venous pressure,hematocrit,neutrophil number and total amount of NF-\u03baB at four time point between two groups.There were no significant difference in the content of activation of NF-\u03baB p65 and acidification of NF-\u03baB p65 of neutrophils at T_0(P>0.05) between two groups.Compared with group C,the content of activation of NF-\u03baB p65 and acidification of NF-\u03baB p65 were significantly lower at T_1,T_2 and T_3 in group\u2164(P<0.05).CONCLUSION The application of 6%hydroxyethyl starch 130/0.4 in CPB could inhibit the expression of NF-\u03baB in peripheral blood neutrophils,thereby reducing the inflammatory response triggered by CPB.",
        "keywords": [
            "NF-kappa B",
            "neutrophils",
            "hetastarch",
            "cardiopulmonary bypass"
        ],
        "authors": [
            {
                "name": "ZHOU Jun",
                "org": "Department of Anesthesia,the First People's Hospital of Foshan,Foshan GUANGDONG ,China"
            },
            {
                "name": "YANG Cheng-xiang",
                "org": "Department of Anesthesia,the First People's Hospital of Foshan,Foshan GUANGDONG ,China"
            },
            {
                "name": "LIN Ai-zhen",
                "org": "Department of Anesthesia,the First People's Hospital of Foshan,Foshan GUANGDONG ,China"
            },
            {
                "name": "ZHONG Ji-ying",
                "org": "Department of Anesthesia,the First People's Hospital of Foshan,Foshan GUANGDONG ,China"
            },
            {
                "name": "LI Heng",
                "org": "Department of Anesthesia,the First People's Hospital of Foshan,Foshan GUANGDONG ,China"
            },
            {
                "name": "LIU Lin-sheng",
                "org": "Department of Anesthesia,the First People's Hospital of Foshan,Foshan GUANGDONG ,China"
            },
            {
                "name": "CHEN Yue-yuan",
                "org": "Department of Anesthesia,the First People's Hospital of Foshan,Foshan GUANGDONG ,China"
            }
        ],
        "venue": "Chinese Journal of New Drugs and Clinical Remedies",
        "year": 2009
    },
    "FIVcmK6w": {
        "id": "FIVcmK6w",
        "title": "Effects of preoperative acute hypervolemic hemodilution on hypercoagulability of patients with colon cancer]",
        "abstract": "Cancer patients have an increased risk of thrombosis after operation because of a hypercoagulable status. Therefore, anticoagulant treatment is necessary for patients with hypercoagulability during perioperative period. This study was to investigate the effect of acute hypervolemic hemodilution (AHHD) with 6% hydroxyethyl starch (HES), or 4% succinylated gelatin (GEL), or lactated Ringer's (RL) solution before operation on the hypercoagulable status and the occurrence of deep venous thrombosis (DVT) of patients with colon cancer.Sixty colon cancer patients with hypercoagulable status underwent operation were randomized into HES, GEL, and RL groups; each group contained 20 patients. The patients were infused with HES, GEL, or RL solution respectively at a dose of 15 ml/kg within 30 min before operation. Preoperative coagulation function was assessed by thrombelastography (TEG). DVT was diagnosed by the color Doppler ultrasonic system.Acute hypervolemic hemodilution with HES solution led to a significant decrease of coagulation index (CI) at 30 min and 2 h after starting operation and 1 h after operation as compared with the prehemodilution value (P<0.01). At 1 h after operation, CI was significantly lower in HES group than in GEL group (P<0.05). At 30 min and 2 h after starting operation and 1 h after operation, CI was significantly lower in HES group than in RL group (P<0.05). Hemodilution with GEL solution lessened CI at 30 min and 2 h after starting operation significantly as compared with the prehemodilution value (P<0.01). At 30 min and 2 h after starting operation, CI was significantly lower in GEL group than in RL group (P<0.05). After operation, DVT in occurred 2 (10%) patients in HES group, 3 (15%) in GEL group, and 10 (50%) in RL group (P<0.05).Acute hypervolemic hemodilution with HES solution and GEL solution can alleviate the hypercoagulability of colon cancer patients during perioperative period and decrease the occurrence of DVT.",
        "keywords": [
            "thrombus",
            "acute hypervolemic hemodilution",
            "hypercoagulability",
            "prophylaxis",
            "surgical operation",
            "colon neoplasm"
        ],
        "authors": [
            {
                "name": "LIANG Hua",
                "org": " Department of Anesthesiology, Affiliated Foshan Hospital, Sun Yat-sen University, Foshan, Guangdong, , P. R. China"
            },
            {
                "name": "YANG Cheng-Xiang",
                "org": " Department of Anesthesiology, Affiliated Foshan Hospital, Sun Yat-sen University, Foshan, Guangdong, , P. R. China"
            },
            {
                "name": "LI Heng",
                "org": " Department of Anesthesiology, Affiliated Foshan Hospital, Sun Yat-sen University, Foshan, Guangdong, , P. R. China"
            },
            {
                "name": "LIU Hong-Zhen",
                "org": " Department of Anesthesiology, Affiliated Foshan Hospital, Sun Yat-sen University, Foshan, Guangdong, , P. R. China"
            },
            {
                "name": "WANG Han-Bing",
                "org": " Department of Anesthesiology, Affiliated Foshan Hospital, Sun Yat-sen University, Foshan, Guangdong, , P. R. China"
            }
        ],
        "venue": "Ai zheng = Aizheng = Chinese journal of cancer",
        "year": 2006
    },
    "Iw1ocUHU": {
        "id": "Iw1ocUHU",
        "title": "EFFECT OF POSTOPERATIVE ANALGESIA WITH FLURBIPROFEN AXETIL COMBINED WITH SULFENTANIL ON PLATELET ACTIVATION IN PATIENTS WITH COLON CANCER",
        "abstract": "Objective: To explore the effect of postoperative analgesia with flurbiprofen axetil combined with sulfentanil on platelets activation in patients with colon cancer.Methods: Forty patients undergoing radical colon carcinoma operation were randomly divided into two groups(n=20).Flurbiprofen axetil combining sulfentanil group(FS) or sulfentanil alone group(S) were used for postoperative patient-controlled analgesia(PCA) respectively.The efficacy of analgesia was assessed by visual analogue scale(VAS) at 1,4,8,12,24 and 48 h after operation.The expression of GP\u2161b /\u2162a and GMP-140 were measured by flow cytometry before anesthesia,2 h after starting operation,4 h,24 h and 48 h after operation.Results:There was no significant difference in analgesic efficacy between two groups(P>0.05).The expression of GP\u2161b/\u2162a and GMP-140 in group FS was increased significantly at 2 h after starting surgery as compared to the baseline values(P<0.05).Compared with group S,the expression of GP\u2161b/\u2162a and GMP-140 at 4 h,24 h and 48 h after operation was significantly lower in group FS(P<0.05).The expression of GP\u2161b/\u2162a and GMP-140 in group S was increased significantly at 2 h after starting operation,4 h and 24 h after operation as compared to that at baseline value(P<0.05).Conclusion:Flurbiprofen axetil combining sulfentanil for postoperative PCA can relief pain effectively and inhibit the excessive platelet activation of patients receiving radical colon carcinoma operation.",
        "keywords": [
            "Platelet",
            "Flurbiprofen axetil",
            "Analgesia",
            "Colon cancer",
            "Sulfentanil"
        ],
        "authors": [
            {
                "name": "LIANG Hua",
                "org": "Department of Anesthesiology,Affiliated FoShan Hospital of Sun Yat-Sen University,FoShan "
            },
            {
                "name": "YANG Cheng-Xiang",
                "org": "Department of Anesthesiology,Affiliated FoShan Hospital of Sun Yat-Sen University,FoShan "
            },
            {
                "name": "LI Heng",
                "org": "Department of Anesthesiology,Affiliated FoShan Hospital of Sun Yat-Sen University,FoShan "
            },
            {
                "name": "WEN Xian-Jie",
                "org": "Department of Anesthesiology,Affiliated FoShan Hospital of Sun Yat-Sen University,FoShan "
            },
            {
                "name": "ZHOU Qiao-Ling",
                "org": "Department of Anesthesiology,Affiliated FoShan Hospital of Sun Yat-Sen University,FoShan "
            },
            {
                "name": "XIONG Yan-Feng",
                "org": "Department of Anesthesiology,Affiliated FoShan Hospital of Sun Yat-Sen University,FoShan "
            }
        ],
        "venue": "Chinese Journal of Pain Medicine",
        "year": 2010
    },
    "kLx8o7wM": {
        "id": "kLx8o7wM",
        "title": "Effects of mibefradil administered intrathecally on the expression of nNOS in spinal cord of the rats following chronic compression of dorsal root ganglion",
        "abstract": "AIM:To investigate the effect of mibefradil administered intrathecally on the pain threshold and the expression of neuron nitric oxide synthase(nNOS)in the spinal cord of the rats following chronic compression of dorsal root ganglion.METHODS:The chronic compression of dorsal root ganglion(CCD)model was adopted.Three different doses of mibefradil,a T-type calcium channel blocker,were administered singly intrathecally to the rats after CCD 5 days.The mechanical withdrawal threshold(MWT)and thermal withdrawal latency(TWL)were determined with von Frey hair and thermal radiation apparatus before mibefradil administered and after mibefradil administered 30 min,60 min,120 min,240 min,and 480 min.Changes of nNOS expression in neurons of the spinal dorsal horn were detected by immunohistochemistry method,and the number of the nNOS positive neurons was counted under microscope.RESULTS:MWT and TWL declined significantly from the first day to the 21st day after CCD.Mibefradil administered intrathecally attenuated significantly both mechanical and thermal hyperagesia of the rats,and markedly inhibited the increase in the nNOS expression.CONCLUSION:These data show that T type calcium channel plays a key role in the CCD-induced mechanical and thermal hyperalgesia and possibly involves in the nNOS expression in the spinal.",
        "keywords": [
            "Nitric-oxide synthase",
            "Mibefradil",
            "Neuropathic pain",
            "T-type",
            "Spinal cord",
            "Calcium channels"
        ],
        "authors": [
            {
                "name": "WEN Xian-jie",
                "org": "Department of Anesthesiology,The First People's Hospital of Foshan City & Affiliated Foshan Hospital of Sun Yat-sen University,Foshan ,China"
            },
            {
                "name": "LIANG Hua",
                "org": "Department of Anesthesiology,The First People's Hospital of Foshan City & Affiliated Foshan Hospital of Sun Yat-sen University,Foshan ,China"
            },
            {
                "name": "YANG Cheng-xiang",
                "org": "Department of Anesthesiology,The First People's Hospital of Foshan City & Affiliated Foshan Hospital of Sun Yat-sen University,Foshan ,China"
            },
            {
                "name": "LI Heng",
                "org": "Department of Anesthesiology,The First People's Hospital of Foshan City & Affiliated Foshan Hospital of Sun Yat-sen University,Foshan ,China"
            },
            {
                "name": "LIU Hong-zhen",
                "org": "Department of Anesthesiology,The First People's Hospital of Foshan City & Affiliated Foshan Hospital of Sun Yat-sen University,Foshan ,China"
            },
            {
                "name": "ZENG Yin-ming",
                "org": "Jiangsu Province Institute of Anesthesiology,Xuzhou Medical College,Xuzhou ,China."
            },
            {
                "name": "LI Zhang-jun",
                "org": "Jiangsu Province Institute of Anesthesiology,Xuzhou Medical College,Xuzhou ,China."
            }
        ],
        "venue": "Chinese Journal of Pathophysiology",
        "year": 2008
    },
    "pjtqG87i": {
        "id": "pjtqG87i",
        "title": "Application of the analytic hierarchy process (AHP) in multi-criteria analysis of the selection of intelligent building systems",
        "abstract": "",
        "keywords": [
            "ahp",
            "intelligent building"
        ],
        "authors": [
            {
                "name": "Johnny K.W. Wong",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hunghom, Kowloon, Hong Kong"
            }
        ],
        "venue": "Building and Environment",
        "year": 2008
    },
    "66ITCUyT": {
        "id": "66ITCUyT",
        "title": "Strengths, Weaknesses, Opportunities, and Threats Analysis of Chinese Construction Companies in the Global Market",
        "abstract": "",
        "keywords": [
            "interviewing",
            "competition",
            "construction industry",
            "china",
            "international development",
            "market assessment",
            "globalization",
            "statistical analysis"
        ],
        "authors": [
            {
                "name": "Weisheng Lu",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Liyin Shen",
                "org": ""
            },
            {
                "name": "Ting Huang",
                "org": ""
            }
        ],
        "venue": "Journal of Management in Engineering",
        "year": 2009
    },
    "TNS3xRZv": {
        "id": "TNS3xRZv",
        "title": "Life-Cycle Management of Construction Projects Based on Virtual Prototyping Technology",
        "abstract": "",
        "keywords": [
            "life cycle management"
        ],
        "authors": [
            {
                "name": "H. L. Guo",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Martin Skitmore",
                "org": ""
            }
        ],
        "venue": "Journal of Management in Engineering",
        "year": 2010
    },
    "37OEnyLz": {
        "id": "37OEnyLz",
        "title": "Strategic alliances: a model for establishing long-term commitment to inter-organizational relations in construction",
        "abstract": "This paper presents a long-term commitment model that can support the long existing change process of a strategic alliance in construction. This model embraces components that help to stimulate the level of employee and management commitment in order to satisfy the stakeholders. Clarifying and comparing the meanings of strategic alliance in management and construction are provided. The paper also suggests the measure of satisfaction under project, business, and corporate levels so that the performance of individual organizations and the alliance can be traced according to these levels. Employee and management satisfaction resulting from the favorable performance of the organizations and the alliance will reinforce their commitment further. This interdependence process occurring between commitment and satisfaction supports a growing and never-ending survival of the strategic alliance. In addition, the paper provides guidelines to set up jointly agreed upon regulations or rules to create a favorable alliance environment that helps to facilitate the establishment of necessary co-operative behavior for the change process. Finally, a case study is presented and measures for four key accomplishments are proposed.",
        "keywords": [
            "commitment",
            "construction",
            "strategic alliance",
            "organizational change",
            "satisfiability"
        ],
        "authors": [
            {
                "name": "Eddie W.L. Cheng",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, HungHom, Kowloon, Hong Kong"
            },
            {
                "name": "Peter E.D. Love",
                "org": "School of Management Information Systems, Edith Cowan University, Perth, Australia"
            },
            {
                "name": "Zahir Irani",
                "org": "Department of Information Systems and Computing, Brunel University, England, UK"
            }
        ],
        "venue": "Building and Environment",
        "year": 2004
    },
    "S4Se7iHc": {
        "id": "S4Se7iHc",
        "title": "Modeling resource management in the building design process by information constraint Petri nets",
        "abstract": "The effect of resource management on the building design process directly influences the development cycle time and success of construction projects. This paper presents the information constraint net (ICN) to represent the complex information constraint relations among design activities involved in the building design process. An algorithm is developed to transform the information constraints throughout the ICN into a Petri net model. A resource management model is developed using the ICN to simulate and optimize resource allocation in the design process. An example is provided to justify the proposed model through a simulation analysis of the CPN Tools platform in the detailed structural design. The result demonstrates that the proposed approach can obtain the resource management and optimization needed for shortening the development cycle and optimal allocation of resources. \u00a9 2012 Elsevier B.V. All rights reserved.",
        "keywords": [
            "building design",
            "information constraint net",
            "petri nets",
            "resource management",
            "simulation"
        ],
        "authors": [
            {
                "name": "Feifei Cheng",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            },
            {
                "name": "Heng Li",
                "org": "University of Technology Sydney(University of Technology,University of Technology Sydney),Sydney,Australia"
            },
            {
                "name": "Yaowu Wang",
                "org": "Harbin Institute of Technology(Harbin Institute of Technology,Harbin Inst. of Technol.),Harbin,China"
            },
            {
                "name": "Martin Skitmore",
                "org": "Queensland University of Technology(Queensland University of Technology),Brisbane,Australia"
            },
            {
                "name": "Perry John Forsythe",
                "org": "University of Technology Sydney(University of Technology,University of Technology Sydney),Sydney,Australia"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2013
    },
    "EOdfO4Oi": {
        "id": "EOdfO4Oi",
        "title": "Rethinking project management and exploring virtual design and construction as a potential solution",
        "abstract": "",
        "keywords": [
            "knowledge management",
            "project management"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Weisheng Lu",
                "org": ""
            },
            {
                "name": "Ting Huang",
                "org": ""
            }
        ],
        "venue": "Construction Management and Economics",
        "year": 2009
    },
    "pbPWdVuj": {
        "id": "pbPWdVuj",
        "title": "Skew detection and correction in document images based on straight-line fitting",
        "abstract": "During document scanning, skew is inevitably introduced into the incoming document image. Since the algorithms for layout analysis and character recognition are generally very sensitive to the page skew, skew detection and correction in document images are the critical steps before layout analysis. In this paper, a novel skew detection method based on straight-line fitting is proposed. And a concept of Eigen-point is introduced. After the relations between the successive Eigen-points in every text line within a suitable sub-region were analyzed, the Eigen-points most possibly laid on the baselines are selected as samples for the straight-line fitting. The average of these baseline directions is computed, which corresponds to the degree of skew of the whole document image. Then a fast skew correction method based on the scanning line model is also presented. Experiments prove that the proposed approaches are fast and accurate.",
        "keywords": [
            "skew detection",
            "eigen-point",
            "incoming document image",
            "connected component",
            "document analysis",
            "skew correction",
            "line model",
            "novel skew detection method",
            "whole document image",
            "layout analysis",
            "eigen-point.",
            "straight-line fitting",
            "page skew",
            "fast skew correction method",
            "document image"
        ],
        "authors": [
            {
                "name": "Yang Cao",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong, PR China"
            },
            {
                "name": "Shuhua Wang",
                "org": "Department of Computer Science and Technology, Nanjing University, Nanjing, PR China"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong, PR China"
            }
        ],
        "venue": "Pattern Recognition Letters",
        "year": 2003
    },
    "czwo9vKL": {
        "id": "czwo9vKL",
        "title": "Application of ANP in process models: An example of strategic partnering",
        "abstract": "Analytic network process (ANP) is a new tool for multi-criteria decision-making (MCDM) but can also be applied in academic research to prioritize factors or criteria. It enhances the function of analytic hierarchy process (AHP) to develop a complete model that can incorporate interdependent relationships between elements from different levels or within levels, which are assumed to be uncorrelated in AHP. Although ANP has recently been applied in the construction field, it cannot be applied easily to process models. This is because its concept does not consider the impacts of an element on another element occurring at different periods in a process, such as stages, phases, etc. This paper uses the strategic partnering model as an example to present a method that helps to form the super-matrix for process models. The procedure of ANP is also highlighted in this paper.",
        "keywords": [
            "decision tool",
            "strategic partnering",
            "analytic network process",
            "process models",
            "multi-criteria decision-making",
            "analytic hierarchy process",
            "process model"
        ],
        "authors": [
            {
                "name": "Eddie W.L. Cheng",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong"
            }
        ],
        "venue": "Building and Environment",
        "year": 2007
    },
    "9bklpOxF": {
        "id": "9bklpOxF",
        "title": "A Group Support System for improving value management studies in construction",
        "abstract": "Group Support System (GSS) is a set of techniques, software and technology designed to focus and enhance the communication, deliberations and decision-making of groups. The thousands of GSS experimental studies and field studies that have been conducted in the past 2 decades demonstrate that GSS is successful in improving the efficiency, reliability and quality of the group decision-making process in meetings. This paper aims to introduce the application of GSS to support Value Management (VM) studies so as to improve the implementation of VM in the construction industry. It begins with an introduction to VM and the problems of implementing VM in construction, e.g. lack of information, lack of participation and interaction and difficulties in conducting evaluation and analysis. This is followed by a description of a GSS framework for VM studies and a specific GSS prototype system to illustrate how this framework can provide support in discussion, information, collaboration and decision analysis to overcome the existing problems in VM studies. The trial run of the prototype by professionals and the benefits of using the proposed system in VM studies have also been discussed in detail.",
        "keywords": [
            "value management",
            "group support system",
            "construction industry",
            "decision analysis",
            "group decision making",
            "field study"
        ],
        "authors": [
            {
                "name": "Qiping Shen",
                "org": ""
            },
            {
                "name": "Jacky K.H Chung",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong"
            },
            {
                "name": "Liyin Shen",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2004
    },
    "RnhskDXj": {
        "id": "RnhskDXj",
        "title": "IT supported collaborative work in A/E/C projects: A ten-year review",
        "abstract": "",
        "keywords": [
            "project management",
            "information technology"
        ],
        "authors": [
            {
                "name": "Xiaolong Xue",
                "org": ""
            },
            {
                "name": "Qiping Shen",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China"
            },
            {
                "name": "Hongqin Fan",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China"
            },
            {
                "name": "Shichao Fan",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2012
    },
    "E1lHXBJz": {
        "id": "E1lHXBJz",
        "title": "The closure of \u201cA multicriteria lifespan energy efficiency approach to intelligent building assessment\u201d, by Chen et al. [Energy and Building 38(5) (2006) 393\u2013409]",
        "abstract": "",
        "keywords": [
            "energy efficient",
            "intelligent building"
        ],
        "authors": [
            {
                "name": "Zhen Chen",
                "org": ""
            },
            {
                "name": "Derek J. Clements-Croome",
                "org": "School of Construction Management and Engineering, The University of Reading, Reading, UK"
            },
            {
                "name": "Ju Hong",
                "org": "Beijing Institute of Civil Engineering and Architecture, Beijing, China"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong, China"
            },
            {
                "name": "Qian Xu",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong, China"
            }
        ],
        "venue": "Energy & Buildings",
        "year": 2007
    },
    "ufVcjZYe": {
        "id": "ufVcjZYe",
        "title": "Development of intelligence analytic models for integrated building management systems (IBMS) in intelligent buildings",
        "abstract": "With the availability of innumerable 'intelligent' building products and the dearth of inclusive evaluation tools, design teams are confronted with the quandary of choosing the apposite building control systems to suit the needs of a particular intelligent building project. The paucity of measures that represent the degree of system intelligence and indicate the desirable goal in intelligent building control systems design inhibits the consumers from comparing numerous products from the viewpoint of intelligence. This article is designed to develop a model for facilitating the system intelligence analysis for the integrated building management system (IBMS) in the intelligent building. To achieve these objectives, systematic research activities are conducted to first develop, test and refine the general conceptual model using consecutive surveys; then, to convert the developed conceptual framework to the practical model; and, finally, to evaluate the effectiveness of the practical model by means of expert validation. The findings of this study suggest that IBMS has a distinctive set of intelligence attributes and indicators. The research findings also indicate that operational benefits of the intelligent building exert a considerable degree of influence on the relative importance of intelligence indicators of the IBMS in the model. This research suggests a benchmark to measure the degree of intelligence of one control system candidate against another.",
        "keywords": [
            "model",
            "integrated building management system",
            "system intelligence",
            "intelligent building",
            "conceptual model",
            "management system",
            "conceptual framework",
            "intelligence analysis",
            "control system"
        ],
        "authors": [
            {
                "name": "Johnny K. W. Wong",
                "org": "School of Urban Development|Faculty of Built Environment and Engineering|Queensland University of Technology"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate|Hong Kong Polytechnic University"
            }
        ],
        "venue": "Intelligent Buildings International",
        "year": 2009
    },
    "3U0dQTPC": {
        "id": "3U0dQTPC",
        "title": "Enabling information sharing between E-commerce systems for construction material procurement",
        "abstract": "Many E-commerce systems for construction material procurement were developed to improve business process, to cut administration cost, and to provide more comprehensive information. Currently these E-commerce systems are owned and operated by many different parties like manufacturers, suppliers, agents and application services providers. These E-commerce systems are non-interoperable which create problems and difficulties for the buyers who use these systems to purchase construction materials. This paper first introduces the application of E-commerce in construction material procurement and then discusses problems of non-interoperable E-commerce systems and benefits of information sharing between them. Two state-of-the-art information technologies, mobile agent and Web services, for enabling information sharing between E-commerce systems are introduced. The system architecture and functions of a prototype system (named E-Union), which utilizes Web services technology to provide information sharing between construction material E-commerce systems, are presented. System evaluation and future works are discussed in the last part.",
        "keywords": [
            "construction material",
            "information sharing",
            "web services",
            "mobile agent",
            "e-commerce",
            "application service provider",
            "system architecture",
            "e commerce",
            "information technology",
            "business process",
            "web service"
        ],
        "authors": [
            {
                "name": "Stephen C.W Kong",
                "org": "Department of Building and Real Estate, Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong"
            },
            {
                "name": "Tim P.L Hung",
                "org": "Department of Building and Real Estate, Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong"
            },
            {
                "name": "John W.Z Shi",
                "org": "Department of Land Surveying and Geo-Informatics, Hong Kong Polytechnic University, Hong Kong"
            },
            {
                "name": "Daniel Castro-Lacouture",
                "org": "Department of Civil Engineering, Ohio University, USA"
            },
            {
                "name": "Miros\u0142aw Skibniewski",
                "org": "School of Civil Engineering, Purdue University, USA"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2004
    },
    "TrGhnON9": {
        "id": "TrGhnON9",
        "title": "From IKEA model to the lean construction concept: A solution to implementation",
        "abstract": "The productivity of the construction industry worldwide has been declining over the past forty years. One approach to improving the situation is by the introduction of lean construction. The IKEA model has been shown to be beneficial when used in the construction context. A framework is developed in which the lean construction concept is embodied within the IKEA model by integrating Virtual Prototyping (VP) technology and its implementation is described and evaluated through a real-life case implementing the lean production philosophy. The operational flows of the IKEA model and lean construction are then compared to analyze the feasibility of IKEA-based lean construction. It is concluded that the successful application of the IKEA model in this context will promote the implementation of lean construction and improve the efficiency of the industry.",
        "keywords": [
            "construction industry",
            "ikea model",
            "lean construction",
            "virtual prototyping"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": "Hong Kong Polytechnic University(Hong Kong Polytechnic University,The Hong Kong Polytechnic University),Hong Kong,China"
            },
            {
                "name": "Hongfend Guo",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            },
            {
                "name": "Yan Li",
                "org": "Center for Assessment and Development of Real Estate(Center for Assessment and Development of Real Estate),Qingshuihe, Shenzhen,China"
            },
            {
                "name": "Martin Skitmore",
                "org": "Queensland University of Technology(Queensland University of Technology),Brisbane,Australia"
            }
        ],
        "venue": "International Journal of Construction Management",
        "year": 2012
    },
    "B5HNDTzE": {
        "id": "B5HNDTzE",
        "title": "An analytic knowledge network process for construction entrepreneurship education",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Zhen Chen",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Stephen C. W. Kong",
                "org": ""
            },
            {
                "name": "Qian Xu",
                "org": ""
            }
        ],
        "venue": "Journal of Management Development",
        "year": 2006
    },
    "hAMlFdhC": {
        "id": "hAMlFdhC",
        "title": "E-commerce system simulation for construction and demolition waste exchange",
        "abstract": "This article introduces a quantitative approach to e-commerce system evaluation based on the theory of process simulation. The general concept of e-commerce system simulation is presented based on the considerations of some limitations in e-commerce system development such as the huge amount of initial investments of time and money, and the long period from business planning to system development, then to system test and operation, and finally to exact return; in other words, currently used system analysis and development method cannot tell investors about some keen attentions such as how good their e-commerce system could be, how many investment repayments they could have, and which area they should improve regarding the initial business plan. In order to exam the value and its potential effects of an e-commerce business plan, it is necessary to use a quantitative evaluation approach and the authors of this article believe that process simulation is an appropriate option. The overall objective of this article is to apply the theory of process simulation to e-commerce system evaluation, and the authors will achieve this though an experimental study on a business plan for online construction and demolition waste exchange. The methodologies adopted in this article include literature review, system analysis and development, simulation modelling and analysis, and case study. The results from this article include the concept of e-commerce system simulation, a comprehensive review of simulation methods adopted in e-commerce system evaluation, and a real case study of applying simulation to e-commerce system evaluation. Furthermore, the authors hope that the adoption and implementation of the process simulation approach can effectively support business decision-making, and improve the efficiency of e-commerce systems.",
        "keywords": [
            "waste exchange",
            "construction and demolition",
            "simulation",
            "e-commerce",
            "process simulation",
            "e commerce"
        ],
        "authors": [
            {
                "name": "Zhen Chen",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong, China"
            },
            {
                "name": "Stephen C.W. Kong",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong, China"
            },
            {
                "name": "Ju Hong",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong, China"
            },
            {
                "name": "Qian Xu",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong, China"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2006
    },
    "475s6I47": {
        "id": "475s6I47",
        "title": "A GIS approach to shopping mall location selection",
        "abstract": "",
        "keywords": [
            "thematic maps",
            "construction industry",
            "spatial data",
            "geographic information system",
            "information technology",
            "decision maker",
            "gis"
        ],
        "authors": [
            {
                "name": "Eddie W.L. Cheng",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": "School of Management, Queensland University of Technology, 2 George Street, Brisbane, QLD4001, Australia"
            },
            {
                "name": "Ling Yu",
                "org": "School of Management, Queensland University of Technology, 2 George Street, Brisbane, QLD4001, Australia"
            }
        ],
        "venue": "Building and Environment",
        "year": 2007
    },
    "8X7NKYO8": {
        "id": "8X7NKYO8",
        "title": "A multicriteria lifespan energy efficiency approach to intelligent building assessment",
        "abstract": "This paper presents a multicriteria decision-making model for lifespan energy efficiency assessment of intelligent buildings (IBs). The decision-making model called IBAssessor is developed using an analytic network process (ANP) method and a set of lifespan performance indicators for IBs selected by a new quantitative approach called energy\u2013time consumption index (ETI). In order to improve the quality of decision-making, the authors of this paper make use of previous research achievements including a lifespan sustainable business model, the Asian IB Index, and a number of relevant publications. Practitioners can use the IBAssessor ANP model at different stages of an IB lifespan for either engineering or business oriented assessments. Finally, this paper presents an experimental case study to demonstrate how to use IBAssessor ANP model to solve real-world design tasks.",
        "keywords": [
            "energy efficiency",
            "life cycle assessment",
            "intelligent building",
            "analytic network process",
            "business model",
            "performance indicator",
            "indexation",
            "energy efficient"
        ],
        "authors": [
            {
                "name": "Zhen Chen",
                "org": ""
            },
            {
                "name": "Derek Clements-Croome",
                "org": "School of Construction Management and Engineering, The University of Reading, Reading, UK"
            },
            {
                "name": "Ju Hong",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong, China"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong, China"
            },
            {
                "name": "Qian Xu",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong, China"
            }
        ],
        "venue": "Energy & Buildings",
        "year": 2006
    },
    "We7z0FUx": {
        "id": "We7z0FUx",
        "title": "Using engineering drawing interpretation for automatic detection of version information in CADD engineering drawing",
        "abstract": "Engineering drawings produced by computer-aided design and drafting (CADD) software are widely employed in the construction industry, as well as many other manufacturing sectors. It is very common for a drawing plan to undergo many revisions, thus, many different versions of the drawing are generated before the final product is achieved. Thus, a drawing management system needs to maintain the history of different versions of drawings, and version control becomes a key function for any drawing management system. In this paper, a knowledge-based version information extraction method is presented. The method analyzes the layout of the drawing frame and extracts the version information with the help of predefined key words. Then a comparison method between two versions of drawing is introduced. The comparison method highlights the differences between two versions of the drawings, so that engineers can locate and find the changes quickly.",
        "keywords": [
            "version information",
            "computer-aided design and drafting",
            "engineering drawing",
            "computer aided design",
            "construction industry",
            "management system",
            "version control",
            "information extraction",
            "knowledge base"
        ],
        "authors": [
            {
                "name": "Yang Cao",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong"
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Yong Liang",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2005
    },
    "AyFd9xZZ": {
        "id": "AyFd9xZZ",
        "title": "Supporting pre-tender construction planning with virtual prototyping",
        "abstract": "",
        "keywords": [
            "construction industry",
            "building information model",
            "research methodology",
            "prototypes",
            "automotive industry",
            "tendering",
            "design methodology",
            "action research",
            "simulation"
        ],
        "authors": [
            {
                "name": "Andrew Baldwin",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Ting Huang",
                "org": ""
            },
            {
                "name": "C. W. Kong",
                "org": ""
            },
            {
                "name": "H. L. Guo",
                "org": ""
            },
            {
                "name": "Neo Chan",
                "org": ""
            },
            {
                "name": "Johnny Wong",
                "org": ""
            }
        ],
        "venue": "Engineering, Construction and Architectural Management",
        "year": 2009
    },
    "v0Rja27h": {
        "id": "v0Rja27h",
        "title": "Pentagon Tri-Wheel Model (PTW): A new project management model based on complexity theory",
        "abstract": "Construction project management (PM) is to ensure the successful delivery of construction projects, and in turn bring benefits to stakeholders. Nonetheless, achieving project success is not an easy task in the construction sector in particular when contemporary projects become more complex, larger, include more variety, face more uncertainty, and have tougher objectives. Various PM models have been introduced while none of them is the panacea to deal with the increasing complexity of construction organizations and projects. This research suggests a Pentagon Tri-Wheel Model (PTW) which builds its foundation on the complexity theory and aims to make sense of the complexity of modern PM. A marriage of critical thinking on existing PM research and practical experience gives birth to the PTW. The model was further demonstrated and validated by conducting a case study on the Hong Kong Disneyland Theme Park. The result of this study suggested that the PTW accommodates the complexity of construction and manyproblems of contemporary PM can be settled by this new PM model.",
        "keywords": [
            "complexity theory",
            "construction management",
            "pentagon tri-wheel model",
            "project management"
        ],
        "authors": [
            {
                "name": "Xian Cheng Yao",
                "org": "China State Construction(China State Construction Engineering Corporation,China State Construction International (Shenzhen) Design Consultant Co. Ltd.,China State Construction International Co.),Beijing,China"
            },
            {
                "name": "Heng Li",
                "org": "Hong Kong Polytechnic University(Hong Kong Polytechnic University,The Hong Kong Polytechnic University),Hong Kong,China"
            }
        ],
        "venue": "International Journal of Construction Management",
        "year": 2009
    },
    "ZzeGZP2F": {
        "id": "ZzeGZP2F",
        "title": "A knowledge-driven management approach to environmental-conscious construction",
        "abstract": "",
        "keywords": [
            "environmental impact",
            "knowledge base",
            "knowledge management",
            "information technology",
            "operations research",
            "best practice",
            "questionnaire survey",
            "environmental management"
        ],
        "authors": [
            {
                "name": "Zhen Chen",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Stephen C. W. Kong",
                "org": ""
            },
            {
                "name": "Qian Xu",
                "org": ""
            }
        ],
        "venue": "Construction Innovation: Information, Process, Management",
        "year": 2005
    },
    "pFmfB3Hm": {
        "id": "pFmfB3Hm",
        "title": "A Decision-making System for Selecting the International Market Entry Mode for Chinese Construction Enterprises",
        "abstract": "Increases in the global economic integration and development prospects of the construction market have been encouraging more and more Chinese enterprises to participate in operations overseas.However,the overseas market environment is complex,volatile and therefore risky.While it is possible to achieve rapid expansion in overseas markets,the operational risks involved can make this unsustainable in the long term.As a result,many Chinese construction enterprises are uncertain of the kind of entry mode to use.The theory of international market entry mode offers some help and provides insights into possible approaches and solutions.However,there are many limitations and deficiencies with the existing theory.For example,the emphasis is on entry from developed to undeveloped countries;it is confined solely to the manufacturing and service industries;and the choice of entry modes does not fully allow for the dynamics of market change.To overcome these limitations,a decision-making system and corresponding analytical framework is developed to accommodate the specific characteristics of the construction industry.",
        "keywords": [
            "influencing factors",
            "international markets",
            "Chinese companies",
            "theory",
            "entry mode",
            "construction",
            "decision-making method"
        ],
        "authors": [
            {
                "name": "Li Heng",
                "org": "The Hong Kong Polytechnic University,Hongkong,China"
            },
            {
                "name": "Jin Zhigang",
                "org": "The Hong Kong Polytechnic University,Hongkong,China"
            }
        ],
        "venue": "Journal of Information Technology in Civil Engineering and Architecture",
        "year": 2009
    },
    "5KvuIyyy": {
        "id": "5KvuIyyy",
        "title": "Competitiveness factors: a study of the real estate market in China",
        "abstract": "",
        "keywords": [
            "china"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Vera Li",
                "org": ""
            },
            {
                "name": "Martin Skitmore",
                "org": ""
            },
            {
                "name": "Johnny Kwok Wai Wong",
                "org": ""
            },
            {
                "name": "Eddie Cheng",
                "org": ""
            }
        ],
        "venue": "Construction Management and Economics",
        "year": 2009
    },
    "oL9PbD9I": {
        "id": "oL9PbD9I",
        "title": "Virtual experiment of innovative construction operations",
        "abstract": "The planning of construction operations is a complicated activity involving abstraction of construction activities from the drawings, choosing of suitable plants and falseworks, allocation of resources on site, planning of safe working place for labourers, and the scheduling of activities sequence. The increasing competition among contractors demands them to adopt innovative construction methods, which have not been used or tested previously. It is not until the beginning of actual construction that the construction planner can realize the validity of his construction operations planning. The lack of tools for the construction planner to evaluate and validate his planning can result in incorrect construction plans, which cause a lot of rework in the construction phase. Virtual Reality (VR) technology, on the other hand, is very likely to provide a solution to the above problem. VR system generates virtual environment containing objects with real world properties and allows user/planner to interact with the objects. This paper proposes an integrated VR system that generates near to reality construction environment for the construction planner to perform construction activities in a real world manner in order to plan, evaluate and validate the construction operations.",
        "keywords": [
            "virtual reality",
            "construction planning",
            "experiment",
            "virtual environment"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China"
            },
            {
                "name": "Zhiliang Ma",
                "org": "Department of Civil Engineering, Tsinghua University, Beijing, China"
            },
            {
                "name": "Qiping Shen",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China"
            },
            {
                "name": "Stephen Kong",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2003
    },
    "OoCuVkaV": {
        "id": "OoCuVkaV",
        "title": "Critical Techniques of Impelling Housing Industrialization in China",
        "abstract": "With the rapid development of urbanization in China,housing industrialization is needed to strongly support the urbanization. However,at present,there is still no an applicable approach to guide the development of the housing industrialization of China. Thus it has become a focus how to successfully advance the process of housing industrialization in the construction industry. On the basis of the many-years experience in the construction field,author wants to introduce the developmental mode of the manufacture industry into the housing industry. This paper presents the three key factors of success in housing industrialization and further provides the critical techniques of impelling housing industrialization,i. e. precast technique and construction virtual prototyping technology. It is cordially expected that this research can provide a reference for the development of housing industrialization in China.",
        "keywords": [
            "Construction virtual prototyping",
            "Housing industrialization",
            "Prefabricate"
        ],
        "authors": [
            {
                "name": "Li Heng",
                "org": "1 Dept. of Building&Real Estate,The Hongkong Polytechnic University,China "
            },
            {
                "name": "Guo Hongling",
                "org": "1 Dept. of Building&Real Estate,The Hongkong Polytechnic University,China "
            },
            {
                "name": "Huang Ting",
                "org": "1 Dept. of Building&Real Estate,The Hongkong Polytechnic University,China "
            },
            {
                "name": "Li Yan",
                "org": "2 Research Center of Shenzhen Real Estate,China"
            }
        ],
        "venue": "Journal of Information Technology in Civil Engineering and Architecture",
        "year": 2009
    },
    "BlVPxszO": {
        "id": "BlVPxszO",
        "title": "Research on the Application Architecture of BIM in Building Projects",
        "abstract": "In order to improve the application of Building Information Modeling(BIM) in the construction industry of China,some real-life examples and comparison methods were employed to compare and analyze the current approaches to apply BIM.The most efficient approach,i.e.the developer-driven BIM application approach,was determined.Furthermore,some suggestions were also presented so as to extend and improve the application of this approach in the construction industry of China.Through determining and improving the BIM application approach,BIM technology can contribute to the construction industry of China.",
        "keywords": [
            "life cycle",
            "BIM",
            "building projects",
            "simulation technology"
        ],
        "authors": [
            {
                "name": "LI Heng",
                "org": "Department of Building and Real Estate,The Hong Kong Polytechnic University,Hong Kong,China"
            },
            {
                "name": "GUO Hong-ling",
                "org": "Department of Building and Real Estate,The Hong Kong Polytechnic University,Hong Kong,China"
            },
            {
                "name": "HUANG Ting",
                "org": "Department of Building and Real Estate,The Hong Kong Polytechnic University,Hong Kong,China"
            }
        ],
        "venue": "Journal of Engineering Management",
        "year": 2010
    },
    "N2Wmc684": {
        "id": "N2Wmc684",
        "title": "Integrating design and construction through virtual prototyping",
        "abstract": "Construction Virtual Prototyping (CVP) is the use of integrated product, process and resource models of construction projects to support the construction planning in virtual environment. This paper describes an integrated framework and process for efficient application of CVP to support project teams on construction planning. It includes specific examples of models and objectives as well as detailed suggestions on how to implement CVP in practice.",
        "keywords": [
            "process simulation",
            "production process",
            "virtual environment"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Ting Huang",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong"
            },
            {
                "name": "C.W. Kong",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong"
            },
            {
                "name": "H.L. Guo",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong"
            },
            {
                "name": "Andrew Baldwin",
                "org": "Department of Civil and Building Engineering, Loughborough University, UK"
            },
            {
                "name": "Neo Chan",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong"
            },
            {
                "name": "Johnny Wong",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2008
    },
    "t7hrb6qz": {
        "id": "t7hrb6qz",
        "title": "Erratum to \u201cParticle swarm optimization-based schemes for resource-constrained project scheduling\u201d [Automation in Construction 14/3 (2005) 393\u2013404]",
        "abstract": "",
        "keywords": [
            "project scheduling"
        ],
        "authors": [
            {
                "name": "Hong Zhang",
                "org": ""
            },
            {
                "name": "Xiaodong Li",
                "org": "School of Management, Harbin Institute of Technology, PR China"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong"
            },
            {
                "name": "Fulai Huang",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2006
    },
    "PTeBihom": {
        "id": "PTeBihom",
        "title": "Discussion of \u201cSafety Risk Identification and Assessment for Beijing Olympic Venues Construction\u201d by Yu Sun, Dongping Fang, Shouqing Wang, Mengdong Dai, and Xiaoquan Lv",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Zhen Chen",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            }
        ],
        "venue": "Journal of Management in Engineering",
        "year": 2009
    },
    "4eHVOVB7": {
        "id": "4eHVOVB7",
        "title": "Using the IKEA model and virtual prototyping technology to improve construction process management",
        "abstract": "",
        "keywords": [
            "business model",
            "construction industry",
            "lean production",
            "manufacturing industry"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Hongling Guo",
                "org": ""
            },
            {
                "name": "Miroslaw Skibniewski",
                "org": ""
            },
            {
                "name": "Martin Skitmore",
                "org": ""
            }
        ],
        "venue": "Construction Management and Economics",
        "year": 2008
    },
    "B9f9DvXF": {
        "id": "B9f9DvXF",
        "title": "Ant colony optimization-based multi-mode scheduling under renewable and nonrenewable resource constraints",
        "abstract": "An ant colony optimization (ACO)-based methodology for solving the multi-mode resource-constrained project scheduling problem (MRCPSP) considering both renewable and nonrenewable resources is presented. With regard to the MRCPSP solution consisting of activity sequencing and mode selection, two levels of pheromones are proposed to guide search in the ACO algorithm. Correspondingly, two types of heuristic information and probabilities as well as related calculation algorithms are introduced. Nonrenewable resource-constraint and elitist-rank strategy are taken into account in updating the pheromones. The flowchart of the proposed ACO algorithm is described, where a serial schedule generation scheme is incorporated to transform an ACO solution into a feasible schedule. The parameter-selection and the resultant performance of the proposed ACO methodology are investigated through a series of computational experiments. It is expected to provide an effective alternative methodology for solving the MRCPSP by utilizing the ACO theory. \u00a9 2013 Elsevier B.V.",
        "keywords": [
            "ant colony optimization",
            "construction projects",
            "multi-mode scheduling",
            "renewable and nonrenewable resource constraints"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": "Hong Kong Polytechnic University(Hong Kong Polytechnic University,The Hong Kong Polytechnic University),Hong Kong,China"
            },
            {
                "name": "Hong Zhang",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2013
    },
    "fnGWA9Oh": {
        "id": "fnGWA9Oh",
        "title": "Rethinking prefabricated construction management using the VP-based IKEA model in Hong Kong",
        "abstract": "Prefabricated construction is regarded by many as an effective and efficient approach to improving construction processes and productivity, ensuring construction quality and reducing time and cost in the construction industry. However, many problems occur with this approach in practice, including higher risk levels and cost or time overruns. In order to solve such problems, it is proposed that the IKEA model of the manufacturing industry and VP technology are introduced into a prefabricated construction process. The concept of the IKEA model is identified in detail and VP technology is briefly introduced. In conjunction with VP technology, the applications of the IKEA model are presented in detail, i.e. design optimization, production optimization and installation optimization. Furthermore, through a case study of a prefabricated hotel project in Hong Kong, it is shown that the VP-based IKEA model can improve the efficiency and safety of prefabricated construction as well as reducing cost and time. \u00a9 2011 Taylor & Francis.",
        "keywords": [
            "construction optimization",
            "design optimization",
            "ikea model",
            "prefabricated construction",
            "virtual prototyping"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": "Hong Kong Polytechnic University(Hong Kong Polytechnic University,The Hong Kong Polytechnic University),Hong Kong,China"
            },
            {
                "name": "Hai Guo",
                "org": "Hong Kong Polytechnic University(Hong Kong Polytechnic University,The Hong Kong Polytechnic University),Hong Kong,China"
            },
            {
                "name": "Martin Skitmore",
                "org": "Queensland University of Technology(Queensland University of Technology),Brisbane,Australia"
            },
            {
                "name": "Ting Huang",
                "org": "Hong Kong Polytechnic University(Hong Kong Polytechnic University,The Hong Kong Polytechnic University),Hong Kong,China"
            },
            {
                "name": "Kityan Chan",
                "org": "Hong Kong Polytechnic University(Hong Kong Polytechnic University,The Hong Kong Polytechnic University),Hong Kong,China"
            },
            {
                "name": "Greg Chan",
                "org": "Hong Kong Polytechnic University(Hong Kong Polytechnic University,The Hong Kong Polytechnic University),Hong Kong,China"
            }
        ],
        "venue": "Construction Management and Economics",
        "year": 2011
    },
    "7t9aXZqp": {
        "id": "7t9aXZqp",
        "title": "Particle swarm optimization-based schemes for resource-constrained project scheduling",
        "abstract": "Particle swarm optimization (PSO) performed through particle flying along the trajectory that will be continuously updated is based to develop a solution-solving scheme for the resource-constrained project scheduling problem (RCPSP). The potential solution to the RCPSP in view of minimizing project duration is represented by the multidimensional particle, where two solution representations, i.e., priority-based representation and permutation-based representation, are respectively considered. The frameworks of the PSOs for the RCPSP according to the two solution representations are developed. Experimental analyses are presented to investigate the performance of the proposed PSO-based methodology, including comparison of the two representations and comparison with other approaches for the RCPSP. The study aims at providing an alternative means for the RCPSP by utilizing the features of PSO, such as particle-updating mechanism that may benefit from the searching experience of one particle itself or the best of all particles in the swarm.",
        "keywords": [
            "resource-constrained",
            "permutation-based representation",
            "project scheduling",
            "particle swarm optimization",
            "priority-based representation"
        ],
        "authors": [
            {
                "name": "Hong Zhang",
                "org": ""
            },
            {
                "name": "Xiaodong Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong"
            },
            {
                "name": "Fulai Huang",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2005
    },
    "AqK1sbDN": {
        "id": "AqK1sbDN",
        "title": "INCITE 2000",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, People's Republic of China"
            },
            {
                "name": "Q.P Shen",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, People's Republic of China"
            },
            {
                "name": "P.E.D Love",
                "org": "School of Architecture and Building, Deakin University, Australia"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2002
    },
    "igLL0Haw": {
        "id": "igLL0Haw",
        "title": "Construction knowledge mining and application of generalized fuzzy network in construction decision management",
        "abstract": "In the trend of globalization and informatization, the construction enterprises are facing the fierce competitions from domestic and foreign markets and the profound changes of the professionalization and informatization of management model, therefore, much challenges come about in the management capabilities and domain knowledge of traditional organization. As knowledge is an important asset of construction industry, a central theme of the competitiveness enhancing in construction enterprises is knowledge management. Because of the organization structure dispersity of construction enterprises and the individual uniqueness of construction projects, knowledge management planning and implementation in the construction enterprises must be a complex and complicated process. Data mining is a key part of knowledge management. The application of data mining algorithms to explore the potential relationships from masses of data directly determines the level of efficiency of knowledge. The paper focus on the investigation of the relationship between related concepts, the research of data mining algorithm, the application of data mining based on knowledge management system of construction enterprises. First, the paper describes the basic concepts of knowledge management, data mining, and the basic situations of construction industry and construction enterprises, investigates the relationship and function of data mining and knowledge management, key and hot issues of data mining algorithms, applications and construction enterprises knowledge management. Second, the paper proposes the architecture of data mining module of construction enterprise. With the actual conditions of construction enterprises, plans six aspects of data mining model of construction enterprises based on cost, schedule, quality, safety, environmental protection and risk issues. Third, the paper designed the generalized fuzzy network (GFN) algorithms and applications. The results of the experiments show that the GFN is more efficient and effective than similar algorithms. Finally, the paper introduces the implementation and application of data mining module of construction enterprises. The achievement of the paper is mainly reflected in the model, algorithm, application of data mining in construction enterprises knowledge management system, with a strong practical and guidance. Key Words: construction industry, construction enterprises, knowledge management, knowledge management systems, data mining, data mining algorithms",
        "keywords": [
            "construction industry",
            "data mining",
            "construction enterprise",
            "generalized fuzzy network",
            "knowledge management",
            "knowledge management system",
            "construction knowledge mining",
            "construction enterprises knowledge management",
            "data mining model",
            "construction project",
            "data mining module",
            "data mining algorithm",
            "construction decision management"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": "Hong Kong Polytechnic University (Hong Kong)"
            },
            {
                "name": "Yuguang Zhou",
                "org": "Hong Kong Polytechnic University (Hong Kong)"
            }
        ],
        "venue": "Construction knowledge mining and application of generalized fuzzy network in construction decision management",
        "year": 2012
    },
    "8StXzvrh": {
        "id": "8StXzvrh",
        "title": "An entry mode decision-making model for the international expansion of construction enterprises",
        "abstract": "Purpose - The purpose of this paper is to provide a new type of entry mode decision-making model for construction enterprises involved in international business. Design/methodology/approach - A hybrid method combining analytic hierarchy process (AHP) with preference ranking organization method for enrichment evaluations (PROMETHEE) is used to aid entry mode decisions. The AHP is used to decompose the entry mode problem into several dimensions and determine the weight of each criterion. In addition, PROMETHEE method is used to rank candidate entry modes and carry out sensitivity analyses. Findings - The proposed decision-making method is demonstrated to be a suitable approach to resolve the entry mode selection decision problem. Practical implications - The research provides practitioners with a more systematic decision framework and a more precise decision method. Originality/value - The paper sheds light on the further development of entry strategies for international construction markets. It not only introduces a new decision-making model for entry mode decision making, but also provides a conceptual framework with five determinants for a construction company entry mode selection based on the unique properties of the construction industry. \u00a9 2012 Emerald Group Publishing Limited.",
        "keywords": [
            "analytic hierarchy process",
            "construction industry",
            "decision making",
            "decision-making model",
            "entry mode",
            "internationalization",
            "market entry",
            "preference ranking organization method for enrichment evaluations",
            "decision making model"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": "Hong Kong Polytechnic University(Hong Kong Polytechnic University,The Hong Kong Polytechnic University),Hong Kong,China"
            },
            {
                "name": "Zhigang Jin",
                "org": "Hong Kong Polytechnic University(Hong Kong Polytechnic University,The Hong Kong Polytechnic University),Hong Kong,China"
            },
            {
                "name": "Vera Li",
                "org": "Hong Kong Polytechnic University(Hong Kong Polytechnic University,The Hong Kong Polytechnic University),Hong Kong,China"
            },
            {
                "name": "Guiwen Liu",
                "org": "Chongqing University(Chongqing University),Chongqing,China"
            },
            {
                "name": "Rm Martin Skitmore",
                "org": "Queensland University of Technology(Queensland University of Technology),Brisbane,Australia"
            }
        ],
        "venue": "Engineering, Construction and Architectural Management",
        "year": 2013
    },
    "vItv4388": {
        "id": "vItv4388",
        "title": "Benchmarking the use of information technology by the quantity surveying profession",
        "abstract": "",
        "keywords": [
            "construction industry",
            "benchmarking",
            "best practice",
            "information technology",
            "computer applications",
            "questionnaire survey",
            "information flow"
        ],
        "authors": [
            {
                "name": "Qiping Shen",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Liyin Shen",
                "org": ""
            },
            {
                "name": "Derek Drew",
                "org": ""
            },
            {
                "name": "Jacky Chung",
                "org": ""
            }
        ],
        "venue": "Benchmarking: An International Journal",
        "year": 2003
    },
    "76Kpl69P": {
        "id": "76Kpl69P",
        "title": "Opportunities and Challenges of BIM Implementation:Current Practice in Hong Kong",
        "abstract": "Building Information Modeling (BIM) has gained rapid acceptance in the building industry in recent years in Hong Kong; both the government and the industry practitioners realize this irreversible trend of changing gradually from traditional 2D representation of building product and fragmented contributions from the stakeholders to 3D product model and streamlined lifecycle management in the near future. This research presents an overview on the implementation of BIM,its current state of practice in Hong Kong. While the primary intention is to introduce the BIM-related works and preliminary benefits; the authors also intend to identify the obstacles and challenges faced by industry practitioners of such implementation in Hong Kong from social and technological contexts. A case study is used to illustrate the benefits of BIM implementation by a large contractor,as well as the technical limitations and difficulties steering toward the \"ideal scenario\" envisaged by using BIM technologies.",
        "keywords": [
            "Technical Limitation",
            "BIM Implementation",
            "BIM",
            "Hong Kong Practice"
        ],
        "authors": [
            {
                "name": "Fan Hongqin",
                "org": "Department of Building and Real Estate,The Hong Kong Polytechnic University"
            },
            {
                "name": "Guo Hongling",
                "org": "Department of Building and Real Estate,The Hong Kong Polytechnic University"
            },
            {
                "name": "Jin Zhigang",
                "org": "Department of Building and Real Estate,The Hong Kong Polytechnic University"
            },
            {
                "name": "Li Heng",
                "org": "Department of Building and Real Estate,The Hong Kong Polytechnic University"
            }
        ],
        "venue": "Journal of Information Technology in Civil Engineering and Architecture",
        "year": 2010
    },
    "QbpHrG3p": {
        "id": "QbpHrG3p",
        "title": "An Empirical Study on Industrial Organization of Chinese Software Service Outsourcing Based on SCP Paradigm",
        "abstract": "How about the software service outsourcing industry in China? Employing the combination research methodologies of field survey, literature research and analysis of the collected data from the survey questionnaire using the SPSS statistic software and its relativity tests, this empirical study analyzed the market structure and performance of Beijing software service outsourcing industry. Based on the SCP paradigm of the industrial organization theory, the conclusion revealed that the market concentration of Beijing software service outsourcing industry was on the low level. The industry possesses the characteristics of low risk, low profit and low product differentiation. There is an apparent trend that increasing profit occurs to the large scale service organizations. Low level price competition dominates the industry at present. The market performance of the industry is therefore low, resulting in the low average profit to most service companies; but the average ratal of these firms is on an upward trend year after year.",
        "keywords": [
            "industrial organization theory",
            "software management",
            "low level price competition",
            "service company",
            "scp paradigm",
            "large scale service organizations",
            "service industries",
            "empirical analysis",
            "product differentiation",
            "spss statistic software",
            "organisational aspects",
            "beijing software service outsourcing industry",
            "collected data analysis",
            "outsourcing",
            "low average profit",
            "software",
            "survey questionnaire",
            "software houses",
            "chinese software service outsourcing",
            "service outsourcing",
            "market structure",
            "industrial organization",
            "correlation",
            "profitability",
            "empirical study",
            "research methodology"
        ],
        "authors": [
            {
                "name": "Jiawen Shen",
                "org": "University of Science and Technology Beijing(University of Science and Technology Beijing),Beijing,China"
            },
            {
                "name": "Heng Li",
                "org": "Hong Kong Polytechnic University(Hong Kong Polytechnic University,The Hong Kong Polytechnic University),Hong Kong,China"
            }
        ],
        "venue": "Management and Service Science",
        "year": 2010
    },
    "VrIPyJGz": {
        "id": "VrIPyJGz",
        "title": "Web services enhanced interoperable construction products catalogue",
        "abstract": "This paper presents a new approach to achieving interoperability between Web-based construction products catalogues. It first introduces the current development of electronic catalogues of construction products. The common system architecture of Web-based electronic products catalogues is discussed, which is followed by a discussion on construction products information standardization and the latest distributed-systems technologies for the communication and exchange of construction products information. The latter part of this paper presents a model of interoperable Web-based construction products catalogue and an implementation of Web services in E-commerce systems to enable the sharing of construction products information.",
        "keywords": [
            "construction products",
            "interoperability",
            "products catalogue",
            "web services",
            "e-commerce",
            "web service",
            "e commerce",
            "system architecture",
            "distributed system"
        ],
        "authors": [
            {
                "name": "Stephen C.W. Kong",
                "org": "Department of Building and Real Estate, Hong Kong Polytechnic University, Hong Kong"
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Yong Liang",
                "org": "Department of Building and Real Estate, Hong Kong Polytechnic University, Hong Kong"
            },
            {
                "name": "Tim Hung",
                "org": "Department of Building and Real Estate, Hong Kong Polytechnic University, Hong Kong"
            },
            {
                "name": "Chimay Anumba",
                "org": "Department of Building and Civil Engineering, Loughborough University, UK"
            },
            {
                "name": "Zhen Chen",
                "org": "Institute of Engineering and Technology, Massey University, New Zealand"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2005
    },
    "2sSVaKky": {
        "id": "2sSVaKky",
        "title": "An empirical model for decision-making on ISO 14000 acceptance in the Shanghai construction industry",
        "abstract": "",
        "keywords": [
            "china",
            "empirical model",
            "environmental impact assessment",
            "environmental management system",
            "iso 14000 series",
            "discriminative model",
            "environmental management",
            "construction industry",
            "questionnaire survey"
        ],
        "authors": [
            {
                "name": "Zhen Chen",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Qiping Shen",
                "org": ""
            },
            {
                "name": "Wei Xu",
                "org": ""
            }
        ],
        "venue": "Construction Management and Economics",
        "year": 2004
    },
    "TUAh44Cj": {
        "id": "TUAh44Cj",
        "title": "Factors constraining the development of professional project management in China's construction industry",
        "abstract": "This paper introduces a survey aimed at identifying the underlying factors that constraint the development of professional project management in China's construction industry. Professional construction project management, which is known as construction supervision (CS) in China, was introduced into China's construction industry in 1988. After more than 10 years of rapid growth, the further development of CS is challenged by a number of arising problems. Based on the findings of the survey, this paper highlights the most significant factors causing these problems. These factors are related not only to CS companies, but also to clients, other construction professionals, and the environment of the construction market. It is anticipated that the discussion of these factors will provide a basis for future strategies to promote the development of CS in China and also provide a useful reference for other developing countries which face similar problems in promoting the applications of professional construction project management in the construction industry.",
        "keywords": [
            "construction supervision",
            "factors",
            "constraints",
            "development",
            "china",
            "construction industry",
            "project management",
            "developing country"
        ],
        "authors": [
            {
                "name": "Guiwen Liu",
                "org": ""
            },
            {
                "name": "Qiping Shen",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China"
            },
            {
                "name": "Liyin Shen",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China"
            }
        ],
        "venue": "International Journal of Project Management",
        "year": 2004
    },
    "faTrWPyS": {
        "id": "faTrWPyS",
        "title": "Personalized method for self-management of trunk postural ergonomic hazards in construction rebar ironwork.",
        "abstract": "Abstract   Construction rebar workers face postural ergonomic hazards that can lead to work-related Lower Back Disorders (LBDs), primarily due to their prolonged awkward working postures required by the job. In a previous study, Wearable Inertial Measurement Units (WIMUs)-based Personal Protective Equipment (PPE) was developed to alert workers when their trunk inclination holding time exceeded acceptable thresholds as defined in ISO standard 11226:2000. However, subsequent field testing identified PPE was ineffective for some workers because the adopted ISO thresholds were not personalized and did not consider differences in individual\u2019s response to postural ergonomic hazards. To address this problem, this paper introduces a worker-centric method to assist in the self-management of work-related ergonomic hazards, based on data-driven personalized healthcare intervention. Firstly, personalized information is gathered by providing each rebar ironworker a WIMU-based personalized mobile health (mHealth) system to capture their trunk inclination angle and holding time data. Then, the captured individual trunk inclination holding times are analyzed by a Gaussian-like probability density function, where abnormal holding time thresholds can be generated and updated in response to incoming trunk inclination records of an individual during work time. These abnormal holding time thresholds are then adapted to be used as personalized trunk inclination holding time recommendations for an individual worker to self-manage their working postures, based on their own trunk inclination records. The proposed worker-centric method to assist in the self-management of ergonomic postural hazards leading to LBDs was field tested on a construction site over a three-month duration. The results of the paired  t -tests indicate that posture scores evaluated by the Ovako Working Posture Analysis System (OWAS) significantly decrease when the personalized recommendation is applied, while increase again when the personalized recommendation is removed. Based on data-driven personalized healthcare intervention, the results demonstrate the significant potential of the proposed worker-centric self-management method for rebar workers in preventing and controlling postural ergonomic hazards during construction rebar ironwork.",
        "keywords": "",
        "authors": [
            {
                "name": "Xuzhong Yan",
                "org": "Department of Building and Real Estate, Faculty of Construction and Environment, Hong Kong Polytechnic University, Hong Kong, China"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, Faculty of Construction and Environment, Hong Kong Polytechnic University, Hong Kong, China"
            },
            {
                "name": "Hong Zhang",
                "org": "Institute of Construction Management, College of Civil Engineering and Architecture, Zhejiang University, Hangzhou 310058, China"
            },
            {
                "name": "Timothy M. Rose",
                "org": "School of Civil Engineering and Built Environment, Science and Engineering Faculty, Queensland University of Technology, Brisbane, Australia"
            }
        ],
        "venue": "Advanced Engineering Informatics",
        "year": 2018
    },
    "Joodv7Ez": {
        "id": "Joodv7Ez",
        "title": "Development of a conceptual model for the selection of intelligent building systems",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Johnny Wong",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong"
            }
        ],
        "venue": "Building and Environment",
        "year": 2006
    },
    "7mWFH12m": {
        "id": "7mWFH12m",
        "title": "Discussion of \u201cISO 14000 and the Construction Industry: Survey in China,\u201d by S. X. Zeng, C. M. Tam, Z. M. Deng, and Vivian W. Y. Tam",
        "abstract": "",
        "keywords": [
            "construction industry"
        ],
        "authors": [
            {
                "name": "Zhen Chen",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            }
        ],
        "venue": "Journal of Management in Engineering",
        "year": 2005
    },
    "lp6nshQZ": {
        "id": "lp6nshQZ",
        "title": "Investigation on intelligent building standard communication protocols and application of IT technologies",
        "abstract": "This paper investigates the frustrating problems of integration and interoperability of Building Automation and Control System (BACS) and presents two possible solutions on the basis of the hierarchy architecture of BACS. One is to employ a unified protocol for the three levels of the BACS networks. The other is the integration at management level. For the first solution, as one candidate, BACnet and its relation with other protocols are evaluated. For the second solution, pros and cons of OPC and Web Services are analyzed and compared. The combination of these two technologies offers good prospects for this solution. A survey on the development of Intelligent Building (IB), the application of IB technologies and the IB standards in China is presented also.",
        "keywords": [
            "integration",
            "standard protocol",
            "web services",
            "intelligent building",
            "building automation system",
            "local area network",
            "interoperability",
            "bacnet",
            "opc",
            "protocol",
            "communication protocol",
            "web service",
            "building automation systems",
            "control system"
        ],
        "authors": [
            {
                "name": "Shengwei Wang",
                "org": ""
            },
            {
                "name": "Zhengyuan Xu",
                "org": "Department of Building Services Engineering, The Hong Kong Polytechnic University, Kowloon, Hong Kong"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Kowloon, Hong Kong"
            },
            {
                "name": "Ju Hong",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Kowloon, Hong Kong"
            },
            {
                "name": "Wen-zhong Shi",
                "org": "Department of Land Surveying and Geo-Informatics, The Hong Kong Polytechnic University, Kowloon, Hong Kong"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2004
    },
    "6F8vq3ym": {
        "id": "6F8vq3ym",
        "title": "A decision-making system for selecting the international market entry mode for Chinese construction enterprises",
        "abstract": "Increases in the global economic integration and development prospects of the construction market have been encouraging more and more Chinese enterprises to participate in operations overseas. However, the overseas market environment is complex, volatile and therefore risky. While it is possible to achieve rapid expansion in overseas markets, the operational risks involved can make this unsustainable in the long term. As a result, many Chinese construction enterprises are uncertain of the kind of entry mode to use. The theory of international market entry mode offers some help and provides insights into possible approaches and solutions. However, there are many limitations and deficiencies with the existing theory. For example, the emphasis is on entry from developed to undeveloped countries; it is confined solely to the manufacturing and service industries; and the choice of entry modes does not fully allow for the dynamics of market change. To overcome these limitations, a decision-making system and corresponding analytical framework is developed to accommodate the specific characteristics of the construction industry. This study should be of interest to construction management practitioners and researchers, as the findings shed light on the further development of entry strategy for international construction market. \u00a9 2010 Faculty of Construction and Land Use, The Hong Kong Polytechnic University.",
        "keywords": [
            "Chinese companies",
            "Construction",
            "Decision-making method",
            "Entry mode",
            "Influencing factors",
            "International markets",
            "Theory"
        ],
        "authors": [
            {
                "name": "Zhigang Jin",
                "org": "Hong Kong Polytechnic University(Hong Kong Polytechnic University,The Hong Kong Polytechnic University),Hong Kong,China"
            },
            {
                "name": "Heng Li",
                "org": "Hong Kong Polytechnic University(Hong Kong Polytechnic University,The Hong Kong Polytechnic University),Hong Kong,China"
            },
            {
                "name": "H. Q. Fan",
                "org": "Hong Kong Polytechnic University(Hong Kong Polytechnic University,The Hong Kong Polytechnic University),Hong Kong,China"
            },
            {
                "name": "P. P. Xu",
                "org": "Hong Kong Polytechnic University(Hong Kong Polytechnic University,The Hong Kong Polytechnic University),Hong Kong,China"
            }
        ],
        "venue": "Proceedings of the 2nd International Postgraduate Conference on Infrastructure and Environment, IPCIE 2010",
        "year": 2010
    },
    "jYryfDG2": {
        "id": "jYryfDG2",
        "title": "Raster to vector conversion of construction engineering drawings",
        "abstract": "A novel method for vectorizing construction engineering drawing images is presented. The method consists of two algorithms: a seed-segment based line-network vectorization algorithm and a knowledge-supported vectorization algorithm designed specially for construction engineering drawings. The seed-segment based algorithm converts a line wholly and a line network globally so that both the quality and speed are satisfied. The knowledge supported vectorization algorithm takes full use of the features and rules of construction engineering drawings to solve the difficulties of vectorization caused by noises and degradations. The performance of this method is discussed at the end of this paper.",
        "keywords": [
            "seed-segment based line conversion",
            "line network vectorization",
            "knowledge supported vectorization",
            "construction engineering drawing",
            "support vector",
            "satisfiability",
            "algorithm design"
        ],
        "authors": [
            {
                "name": "Jiqiang Song",
                "org": ""
            },
            {
                "name": "Feng Su",
                "org": "State Key Laboratory of Novel Software Technology, Nanjing University, 210093 Nanjing, China"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong, China"
            },
            {
                "name": "Shijie Cai",
                "org": "State Key Laboratory of Novel Software Technology, Nanjing University, 210093 Nanjing, China"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2002
    },
    "4hrYgHWT": {
        "id": "4hrYgHWT",
        "title": "A framework for developing a unified B2B e-trading construction marketplace",
        "abstract": "With its great explosion and the advancement of related technology and services, such as the World Wide Web (WWW), the Internet has provided a rich environment for developing Internet-based electronic commerce (e-commerce) applications in construction. Among the different types of e-commerce, business-to-business (B2B) is the most widely used. The B2B e-trading marketplaces (also called B2B-exchanges), which have sparked a revolution in the way of trading products between buyers and suppliers, are an essential component of B2B applications. However, many e-trading marketplaces have been developed and hosted by different construction products and services providers, and each forms a closed system with their own customers and clients. In this paper, the concept of e-union is presented, which integrates the services provided by different e-trading construction sites to provide an open e-trading service. The design of a mobile agent-enabled framework for building such an open e-trading marketplace environment is described, along with a prototypical implementation.",
        "keywords": [
            "b2b",
            "marketplace",
            "e-trading",
            "framework",
            "electronic commerce",
            "closed system",
            "mobile agent",
            "e trading",
            "e commerce",
            "service provider",
            "world wide web"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China"
            },
            {
                "name": "Jiannong Cao",
                "org": "Department of Computing, The Hong Kong Polytechnic University, Hong Kong, China"
            },
            {
                "name": "Daniel Castro-Lacouture",
                "org": "School of Civil Engineering, Purdue University, West Lafayette, IN 47907-1294, USA"
            },
            {
                "name": "Miros\u0142aw Skibniewski",
                "org": "Division of Construction Engineering and Management, School of Civil Engineering, Purdue University, West Lafayette, IN 47907-1294, USA"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2003
    },
    "RdC58EsN": {
        "id": "RdC58EsN",
        "title": "REALMEDIA: providing multimedia-based real-estate services through the Internet",
        "abstract": "This paper presents the design and implementation of a software system, known as REALMEDIA , which provides Web-based, multimedia real-estate services on the Internet. REALMEDIA is innovative in that it is designed to provide both on-line services to clients and a tool for maintaining the system to real-estate agent. The software consists of a web-based interface , a client side editor and an application server . The web interface is used by both the customer and the real-estate agent to request particular services. When used by a customer, it allows the potential buyer to select and view desired properties, and to make an appointment with agents. Multimedia information, which integrates text, graphics and video clips, are presented to the customer. When used by the agent, the web interface allows the agent to dynamically update the contents of the web page and to manipulate property details through the Client Side Editor. The application server acts as a bridge between the Web Interface and the Client Side Editor. The computational architecture and major components of REALMEDIA as well as its implementation using JAVA, TCP/IP and FTP will be described.",
        "keywords": [
            "real-estate",
            "internet",
            "realmedia",
            "software systems",
            "web interface",
            "real estate",
            "web pages",
            "computer architecture",
            "application server"
        ],
        "authors": [
            {
                "name": "J Cao",
                "org": ""
            },
            {
                "name": "Jackie Y.K Chan",
                "org": "Department of Computing, Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China"
            },
            {
                "name": "Lamine Mahdjoubi",
                "org": "School of Engineering and Built Environment, University of Wolverhampton, UK"
            },
            {
                "name": "Peter E.D Love",
                "org": "School of Architecture and Building, Deakin University, Australia"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2001
    },
    "GfVoa0a5": {
        "id": "GfVoa0a5",
        "title": "Construction IT and the \u2018tipping point\u2019",
        "abstract": "Using the \u201ctipping point\u201d as a metaphor, the paper argues that the construction industry is ready to reap the benefits of using information technologies. Construction IT as an appropriating discipline is enabling us to have devices to speculate about designs, to have innovative modes of collaboration, communication and practice. \u201cVirtuality\u201d is the password for construction professionals to cross over into the experimental realms of installation and operation. The paper identifies the ingredients needed to \u2018tip\u2019 the balance for an accelerated penetration of information technologies into the construction industry. Core technologies are described as the prime mover of radical transformation in the construction industry.",
        "keywords": [
            "knowledge management",
            "tipping point",
            "construction industry",
            "information technology"
        ],
        "authors": [
            {
                "name": "Peter Brandon",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University"
            },
            {
                "name": "Qiping Shen",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2005
    },
    "1Q1Usb6g": {
        "id": "1Q1Usb6g",
        "title": "Knowledge-Driven ANP Approach to Vendors Evaluation for Sustainable Construction",
        "abstract": "",
        "keywords": [
            "evaluation",
            "analytic network process",
            "construction management",
            "sustainable development",
            "procurement"
        ],
        "authors": [
            {
                "name": "Zhen Chen",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Andrew Ross",
                "org": ""
            },
            {
                "name": "Malik M. A. Khalfan",
                "org": ""
            },
            {
                "name": "Stephen C. W. Kong",
                "org": ""
            }
        ],
        "venue": "Journal of Construction Engineering and Management-asce",
        "year": 2008
    },
    "iIC8hLmu": {
        "id": "iIC8hLmu",
        "title": "Viewpoint: Using Information Technology to Enhance Engineering Education",
        "abstract": "This paper reviews three learning models and information technologies that can be used to support the effective application of these learning models in engineering higher education. The effectiveness of an information technology is analysed through the appropriateness of the technology in supporting a particular learning model. The mapping of information technologies to learning models identifies technologies in which engineering schools should invest in order to improve their educational environment and quality.",
        "keywords": [
            "engineering education",
            "information technology",
            "higher education"
        ],
        "authors": [
            {
                "name": "HENG LI",
                "org": "Dept of Building and Real Estate|Hong Kong Polytechnic University"
            }
        ],
        "venue": "",
        "year": 1997
    },
    "g2OYCFfF": {
        "id": "g2OYCFfF",
        "title": "A framework for identification and representation of client requirements in the briefing process",
        "abstract": "",
        "keywords": [
            "functional analysis",
            "information analysis",
            "research methodology"
        ],
        "authors": [
            {
                "name": "Qiping Shen",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Jacky Chung",
                "org": ""
            },
            {
                "name": "Pui-Yee Hui",
                "org": ""
            }
        ],
        "venue": "Construction Management and Economics",
        "year": 2004
    },
    "MdbnxBrH": {
        "id": "MdbnxBrH",
        "title": "An application of bar-code system for reducing construction wastes",
        "abstract": "This paper presents a group-based incentive reward program (IRP) to encourage workers to minimize avoidable wastes of construction materials by rewarding them according to the amounts and values of materials they saved. Bar-code technique is used to facilitate effective management of construction materials. An IRP-integrated construction management system is also introduced to avoid jerrybuilding and solve reschedule problem due to rework of quality failure. An experiment is conducted on a residential project in Hong Kong and results from the experiment demonstrate the effectiveness of the IRP in motivating workers to reduce construction wastes. Discussions on the relationship between construction waste reduction and time and cost performances are also presented. Difficulties and challenges of applying IRP are also discussed.",
        "keywords": [
            "construction wastes",
            "incentive reward program (irp)",
            "bar-code system",
            "construction management"
        ],
        "authors": [
            {
                "name": "Chen Zhen",
                "org": ""
            },
            {
                "name": "Li Heng",
                "org": ""
            },
            {
                "name": "Wong C.T.C.",
                "org": ""
            }
        ],
        "venue": "Automation in Construction",
        "year": 2002
    },
    "epEFlhIh": {
        "id": "epEFlhIh",
        "title": "Scenarios for applying RFID technology in construction project management",
        "abstract": "Research highlights \u25ba RFID has great potential in improving CPM goals such as time, quality, cost, safety, and environment by applying it in the management of materials, labours, and machinery. \u25ba RFID can largely enhance the real\u2010time information visibility and traceability in CPM. \u25ba RFID is slowly adopted in the construction industry owing to its many technical, financial, and ethical hurdles. \u25ba The industry should be well informed of the benefits of the RFID technology.",
        "keywords": [
            "scenarios",
            "construction",
            "information management",
            "information visibility and traceability",
            "radio frequency identification",
            "project management",
            "scientific research",
            "construction industry",
            "supply chain management",
            "real time"
        ],
        "authors": [
            {
                "name": "Weisheng Lu",
                "org": ""
            },
            {
                "name": "George Q. Huang",
                "org": "Dept. of Industrial and Manufacturing Systems Engineering, Faculty of Engineering, the University of Hong Kong, Hong Kong"
            },
            {
                "name": "Heng Li",
                "org": "Dept. of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2011
    },
    "CXX6ktj4": {
        "id": "CXX6ktj4",
        "title": "Using game technologies to improve the safety of construction plant operations.",
        "abstract": "Many accidents occur world-wide in the use of construction plant and equipment, and safety training is considered by many to be one of the best approaches to their prevention. However, current safety training methods/tools are unable to provide trainees with the hands-on practice needed. Game technology-based safety training platforms have the potential to overcome this problem in a virtual environment. One such platform is described in this paper - its characteristics are analysed and its possible contribution to safety training identified. This is developed and tested by means of a case study involving three major pieces of construction plant, which successfully demonstrates that the platform can improve the process and performance of the safety training involved in their operation. This research not only presents a new and useful solution to the safety training of construction operations, but illustrates the potential use of advanced technologies in solving construction industry problems in general.",
        "keywords": [
            "construction",
            "plant",
            "game technology",
            "safety training",
            "operation",
            "equipment"
        ],
        "authors": [
            {
                "name": "Hongling Guo",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong"
            },
            {
                "name": "Greg Chan",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong"
            },
            {
                "name": "Martin Skitmore",
                "org": "School of Urban Development, Queensland University of Technology, Gardens Point, Brisbane Q4001, Australia"
            }
        ],
        "venue": "Accident; analysis and prevention",
        "year": 2012
    },
    "xsbQHWyq": {
        "id": "xsbQHWyq",
        "title": "An integrated study of construction virtual prototyping system",
        "abstract": "Construction project is a complicated and dynamic process which is impossible to have the ability to try before build. And for most of construction enterprises in China, traditional methods such as bar chart and column diagram are always used for denoting the schedule and resource utilization, which are very difficult to explicitly show the variational construction process. In order to change the old construction management mode, the paper designs a construction information management system by making use of virtual prototyping technology for graphically simulating the whole construction process and visually realizing the dynamic management under various operation environments including the schedule, labor, equipment and all physical layout, etc. The system called construction virtual prototyping system (CVPS) includes the three aspects of mechanism analysis: (1) integrated platform; (2) development environment; (3) design. Basically, its use can help find the problems in advance before the design and construction process so as to minimize the risk, cost, and the makespan or total project duration. \u00a9 2010 Faculty of Construction and Land Use, The Hong Kong Polytechnic University.",
        "keywords": [
            "Integrated platform",
            "Optimization",
            "Process simulation",
            "Scheduling",
            "Virtual prototyping"
        ],
        "authors": [
            {
                "name": "Xundi Diao",
                "org": "Shanghai Jiaotong University(Shanghai Jiaotong University,Shanghai Jiao Tong University,Shanghai Jiaotong Univ.),Shanghai,China"
            },
            {
                "name": "Heng Li",
                "org": "Hong Kong Polytechnic University(Hong Kong Polytechnic University,The Hong Kong Polytechnic University),Hong Kong,China"
            },
            {
                "name": "S. X. Zeng",
                "org": "Shanghai Jiaotong University(Shanghai Jiaotong University,Shanghai Jiao Tong University,Shanghai Jiaotong Univ.),Shanghai,China"
            }
        ],
        "venue": "Proceedings of the 2nd International Postgraduate Conference on Infrastructure and Environment, IPCIE 2010",
        "year": 2010
    },
    "MMBoIEhS": {
        "id": "MMBoIEhS",
        "title": "Simulation-based optimization for dynamic resource allocation",
        "abstract": "An optimization methodology that integrates discrete-event simulation (DES) with a heuristic algorithm is developed to optimize dynamic resource allocation for construction scheduling. This heuristic algorithm is based on the objective of minimizing project duration and would consider activating multiple activities at the same time based on limited quantities of resources. The optimization is implemented through discrete-event simulation that is able to describe complex operational systems through simulation models, without the need to build mathematical models. The effectiveness of the simulation-based optimization is demonstrated through an application, where the impact of the optimized allocation is compared with those of other ones. The proposed methodology provides an alternative to optimize resource flow for scheduling and broadens the application potential of discrete-event simulation in the construction field.",
        "keywords": [
            "discrete-event simulation",
            "resource allocation",
            "optimization",
            "heuristic algorithm",
            "discrete event simulation",
            "mathematical model",
            "flowchart",
            "simulation model",
            "application",
            "construction industry",
            "operating system",
            "implementation",
            "efficiency",
            "scheduling",
            "project management",
            "methodology",
            "algorithm"
        ],
        "authors": [
            {
                "name": "Hong Zhang",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Humg Hom, Kowloon, Hong Kong"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2004
    },
    "vyKunFGc": {
        "id": "vyKunFGc",
        "title": "Discussion of \u201cUsing Analytic Network Process to Predict the Performance of International Construction Joint Ventures\u201d by Beliz Ozorhon, Irem Dikmen, and M. Talat Birgonul",
        "abstract": "",
        "keywords": [
            "analytic network process"
        ],
        "authors": [
            {
                "name": "Zhen Chen",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            }
        ],
        "venue": "Journal of Management in Engineering",
        "year": 2009
    },
    "cXAnFmro": {
        "id": "cXAnFmro",
        "title": "Optimization of curved roof surface design using GA",
        "abstract": "Purpose: Due to the increasing complexity of curved roof surface design and the inadequate optimisation algorithms in design software, the optimisation of curved roof surface design needs to be studied further. The purpose of this paper is to develop an alternative approach to improve the efficiency and effectiveness of curved roof surface design of buildings. Design/methodology/approach: To achieve the purpose, an optimisation method/tool is developed through reviewing the application of CATIA and integrating genetic algorithm with CATIA; and the effectiveness to perform the GA-based optimisation method is demonstrated by using a real-life case study. Furthermore, a comparison among different optimisation algorithms currently available in the CATIA system is conducted. Findings: Through the case study and the comparison, it is found that the GA-based method can improve the performance of optimisation for curved roof surface design in the CATIA system; however, further research work is required for the best global optimisation result. Originality/value: The paper proposes an optimisation method for curved roof surface design through integrating genetic algorithm with CATIA. This method improves the current method of curved roof surface design. \u00a9 Emerald Group Publishing Limited.",
        "keywords": [
            "building design",
            "curved roof design",
            "genetic algorithm",
            "optimum design",
            "roofs"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": "Hong Kong Polytechnic University(Hong Kong Polytechnic University,The Hong Kong Polytechnic University),Hong Kong,China"
            },
            {
                "name": "Hongfend Guo",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            },
            {
                "name": "Stephen Kong",
                "org": "Hong Kong Polytechnic University(Hong Kong Polytechnic University,The Hong Kong Polytechnic University),Hong Kong,China"
            },
            {
                "name": "Zhen Chen",
                "org": "Liverpool John Moores University(Liverpool John Moores University ^),Liverpool,United Kingdom"
            }
        ],
        "venue": "Journal of Engineering, Design and Technology",
        "year": 2012
    },
    "LSFmo1gK": {
        "id": "LSFmo1gK",
        "title": "An integrative methodology for environmental management in construction",
        "abstract": "A remarkable difference between the registration rate of ISO 14001 environmental management system (EMS) and the implementation rate of environmental impact assessment (EIA) in construction industry in Mainland China indicates that there may be little coordination between the implementation of the EIA and the EMS in construction projects in Mainland China, and the EIA practice may not really serve as a tool to promote environmental management (EM) in construction. Since the China Environmental Protection Bureau recently enacted to implement the environmental supervision system in construction project supervision, contractors have to pay greater attention to adopt and implement EM in construction. In this regard, this paper presents an integrative methodology (E+) for dynamic EIA in construction, which integrates various EM approaches with a general EMS process throughout all construction stages in a construction project. The E+ is expected to effectively and efficiently assist contractors to enhance their environmental performances in China.",
        "keywords": [
            "environmental impact assessment",
            "environmental management",
            "environmental protection",
            "environmental management system",
            "construction industry"
        ],
        "authors": [
            {
                "name": "Zhen Chen",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Ju Hong",
                "org": "Research Center for Construction Management and Construction IT, Department of Building and Real Estate, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hongkong, PR China"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2004
    },
    "qdRdoE1e": {
        "id": "qdRdoE1e",
        "title": "Application of integrated GPS and GIS technology for reducing construction waste and improving construction efficiency",
        "abstract": "This paper presents a study on applying an integrated Global Position System (GPS) and Geographacial Information System (GIS) technology to the reduction of construction waste. During the study, a prototype study is developed from automatic data capture system such as the barcoding system for construction material and equipment (M&E) management onsite, whilst the integrated GPS and GIS technology is combined to the M&E system based on the Wide Area Network (WAN). Then, a case study is conducted to demonstrate the deployment of the system. Experimental results indicate that the proposed system can minimize the amount of onsite material wastage.",
        "keywords": [
            "construction waste",
            "enterprise resource planning (erp)",
            "global position system gps",
            "geographacial information system gis",
            "material and equipment management",
            "enterprise resource planning erp",
            "global position system (gps)",
            "geographacial information system (gis)",
            "data capture",
            "information system"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Zhen Chen",
                "org": "Institute of Technology and Engineering, Massey University, Palmerston North, New Zealand"
            },
            {
                "name": "Liang Yong",
                "org": "Department of Building and Real Estate, Hong Kong Polytechnic University, Hong Kong, China"
            },
            {
                "name": "Stephen C.W. Kong",
                "org": "Department of Civil and Building Engineering, Loughborough University, Loughboirough, UK"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2005
    },
    "WEqhbOlz": {
        "id": "WEqhbOlz",
        "title": "Automatic acquisition of rules for 3D reconstruction of construction components",
        "abstract": "Aiming at the rule-based recognition system for architectural structure drawings (ASDs), this paper presents a sample-based method that will automatically extract the geometric features of architectural objects and convert the features into recognition rules. When users designate the first sample of one type of objects, this method automatically analyzes and extracts the features useful for drawing recognition. Aided by a little interactive operation, recognition rules for this type of objects are generated. When a new sample of one object is designated through automatically comparing the new features and the old, this method analyzes and modifies the features of this object, then generates new rules. Along with new object types or new representations of old types are processed, rules of the recognition system are perfected continuously without modifying the program. This method can bring to the drawing recognition system higher self-adaptability and practicability.",
        "keywords": [
            "construction component",
            "rule acquisition",
            "self-adapting recognition",
            "architectural structure drawing",
            "3d reconstruction",
            "rule based"
        ],
        "authors": [
            {
                "name": "Ruoyu Yang",
                "org": "State Key Laboratory of Novel Software Technology, Nanjing University, Nanjing 210093, China"
            },
            {
                "name": "Yang Cao",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, China"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, China"
            },
            {
                "name": "Shengwei Wang",
                "org": "Department of Building Services Engineering, The Hong Kong Polytechnic University, China"
            },
            {
                "name": "Qiping Shen",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, China"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2004
    },
    "7EgVs1TG": {
        "id": "7EgVs1TG",
        "title": "EnvironalPlanning: Analytic Network Process Model for Environmentally Conscious Construction Planning",
        "abstract": "",
        "keywords": [
            "environmental protection",
            "project management",
            "analytic network process",
            "planning",
            "pollution",
            "construction industry",
            "construction management"
        ],
        "authors": [
            {
                "name": "Zhen Chen",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Conrad T. C. Wong",
                "org": ""
            }
        ],
        "venue": "Journal of Construction Engineering and Management-asce",
        "year": 2005
    },
    "dECfwLJi": {
        "id": "dECfwLJi",
        "title": "A total environmental risk assessment model for international hub airports",
        "abstract": "This paper presents a multi-criteria decision analysis for environmental risk assessment (ERA) with regard to avoiding and eliminating damages and loss under natural disasters in international airport projects. It starts from an assumption that the strategy of eliminating damages and losses under natural disasters is related to the location selection problem, and it is necessary to use the multi-criteria decision analysis for calculated decision-making support. The paper uses the analytic network process (ANP) to demonstrate one of its utility modes in decision-making support to location selection problems, which aims at an evaluation of different projects from different locations. A set of generic criteria for risk assessment at international projects was put forward to support ANP modelling, and it was due to the consideration of social, technical, economic, environmental and political (STEEP) criteria related to the built, social and natural (BSN) trinity environment of international airport projects. At the end, an experimental case study on three international hub airports in China is given to test the ANP model called ERA.Airport, and it is concluded that ANP can be effectively used for risk assessment in the specific utility mode. The ERA.Airport is a generic multi-criteria decision-making model and can be used across the world for accurate environmental risk assessment for international airports. \u00a9 2011 Elsevier Ltd. and IPMA.",
        "keywords": [
            "airport",
            "china",
            "environmental risks",
            "location selection",
            "risk assessment",
            "urban clusters",
            "analytic network process",
            "multi criteria decision analysis",
            "natural disaster"
        ],
        "authors": [
            {
                "name": "Zhen Chen",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, China"
            },
            {
                "name": "Hong Ren",
                "org": "School of Construction Management and Real Estate, Chongqing University, Chongqing, China"
            },
            {
                "name": "Qian Xu",
                "org": "School of the Built Environment, Heriot\u2013Watt University, Edinburgh, UK"
            },
            {
                "name": "Ju Hong",
                "org": "School of Civil and Transportation Engineering, Beijing University of Civil Engineering and Architecture, Beijing, China"
            }
        ],
        "venue": "International Journal of Project Management",
        "year": 2011
    },
    "UJt9gIUa": {
        "id": "UJt9gIUa",
        "title": "Multi-agent simulation of the dynamic evolutionary process in Chinese urban housing market based on the GIS: The case of Beijing",
        "abstract": "In order to analyze the dynamic evolutionary process of Chinese emerging housing market, the paper defines the behavioral functions of household agents in terms of demand generation, information search and price negotiation, and incorporates multi-agent technique and geographic information system to conduct a series of simulation studies on Beijing housing market. By setting different market scenarios, the impacts of new housing supply and information level on Beijing housing market are addressed. The findings show that, Beijing housing market is characterized by the prominent urban expansion with the formation of consolidated residential zones outside the 5th ring road; the growth in new housing supply can reduce the buyer search duration significantly, and lead the buyer search flow to the new housing market; higher information level can increase the sales of resale housing market, but inhibit the sales and time on market for new-built houses to some extent. \u00a9 2013 The Authors.",
        "keywords": [
            "china",
            "evolutionary process",
            "geographic information system",
            "housing market",
            "multi-agent simulation"
        ],
        "authors": [
            {
                "name": "Hong Zhang",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            },
            {
                "name": "Yang Li",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            },
            {
                "name": "Heng Li",
                "org": "Hong Kong Polytechnic University(Hong Kong Polytechnic University,The Hong Kong Polytechnic University),Hong Kong,China"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2013
    },
    "TH4B6A7Y": {
        "id": "TH4B6A7Y",
        "title": "Information management system for market analysis of real estate development projects",
        "abstract": "A information management system was developed for market analysis of real estate development projects. The system is based on current status of market analyses using geographic information systems (GIS), network analysis, and database technologies. The opinions of field experts were obtained for the results from a prototype system. The system can assist market analyses of real estate development projects, reduce costs, and improve working efficiency.",
        "keywords": [
            "Database",
            "Geographic information system (GIS)",
            "Market analysis",
            "Real estate development projects"
        ],
        "authors": [
            {
                "name": "Zhiliang Ma",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            },
            {
                "name": "Siyuan Fu",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            },
            {
                "name": "Heng Li",
                "org": "Hong Kong Polytechnic University(Hong Kong Polytechnic University,The Hong Kong Polytechnic University),Hong Kong,China"
            },
            {
                "name": "Yonghe Li",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            }
        ],
        "venue": "Qinghua Daxue Xuebao/Journal of Tsinghua University",
        "year": 2007
    },
    "sIOCOvnc": {
        "id": "sIOCOvnc",
        "title": "Design of spatial decision support systems for property professionals using MapObjects and Excel",
        "abstract": "Spatial decision support systems (SDSS) are a branch of data-driven decision support systems that utilize spatial data in the decision-making process. This paper introduces a simple and inexpensive way of designing SDSS to support property professionals in their decisions concerning locations, throughout the property development process. The proposed SDSS integrate traditional decision support systems with geographical information systems (GIS) to have the best of both worlds: GIS capabilities and modeling ability. The design of the SDSS utilizes two widely used software packages: Excel and MapObjects. Excel is a spreadsheet program that has the strong capability to construct models using its built-in functions and Visual Basic for Application (VBA). MapObjects is a collection of embeddable mapping and GIS components from ESRI. Using these ActiveX automation objects, application developers can add mapping and GIS capabilities to applications. When MapObjects controls are integrated with an Excel sheet, they have the ability to save and show maps, query addresses, and carry out other interactive functions. The development environment and the working mechanism for the proposed systems are introduced, which is further elaborated by providing a case study on how the proposed SDSS can be used by property professionals.",
        "keywords": [
            "sdss",
            "property valuation",
            "mapobjects",
            "dss",
            "gis",
            "excel",
            "decision making process",
            "spatial data",
            "development process",
            "application development",
            "decision support system",
            "geographic information system",
            "development environment"
        ],
        "authors": [
            {
                "name": "Yunbo Li",
                "org": "School of Management, Harbin Institute of Technology, Harbin 150016, China"
            },
            {
                "name": "Qiping Shen",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2004
    },
    "kWHx9U5f": {
        "id": "kWHx9U5f",
        "title": "Collaborative system for document editing based on network and commonly used word processing software",
        "abstract": "In practice, it is common that several members collaborate to prepare a document. For example, in the domain of construction, it is necessary to collaborate with others to prepare investment proposals, feasibility analysis reports, etc.. But little software for document preparation can support this process well up to now. Accordingly, the paper proposes a solution for developing a general purpose collaborative system for document preparation based on network and commonly used word processing software. A prototype system has been implemented. It provides a new approach to developing a collaborative system for document preparation.",
        "keywords": [
            "Collaborative system",
            "Document",
            "Document editing",
            "Word processing"
        ],
        "authors": [
            {
                "name": "Zhiliang Ma",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            },
            {
                "name": "Yonghe Li",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            },
            {
                "name": "Heng Li",
                "org": "Hong Kong Polytechnic University(Hong Kong Polytechnic University,The Hong Kong Polytechnic University),Hong Kong,China"
            }
        ],
        "venue": "Jisuanji Gongcheng/Computer Engineering",
        "year": 2006
    },
    "t80TL0Rm": {
        "id": "t80TL0Rm",
        "title": "Comparative study of analytical rental model and statistical models for predicting house rental levels",
        "abstract": "The need for a house rental model in Townsville, Australia is addressed. Models developed for predicting house rental levels are described. An analytical model is built upon a priori selected variables and parameters of rental levels. Regression models are generated to provide a comparison to the analytical model. Issues in model development and performance evaluation are discussed. A comparison of the models indicates that the analytical model performs better than the regression models.",
        "keywords": [
            "regression model"
        ],
        "authors": [
            {
                "name": "Heng LI",
                "org": "Department of Building and Real Estate, Hong Kong Polytechnic University, Kowloon, Hong Kong"
            },
            {
                "name": "Vera Li",
                "org": "Coopers and Lybrand, 333 Collins Street, Victoria 3000, Australia"
            },
            {
                "name": "Martin Skitmore",
                "org": "School of Building, QUT, Brisbane 4000, Australia"
            }
        ],
        "venue": "Building and Environment",
        "year": 1997
    },
    "83gHy16A": {
        "id": "83gHy16A",
        "title": "Real estate confidence index based on Web GIS and SPSS WebAPP",
        "abstract": "Real estate confidence index, as an efficient and effective information-oriented measure, is being studied and applied to the China\u2019s real estate market. It not only assists government with the macro control of real estate market, but also guides investment and consumption. In order to assure the accuracy and real time of the RECI, more factors should be considered and an efficient system based on IT is needed. This paper presents a set of real estate confidence indices via considering synthetically efficient demand and supply, latent demand and latent supply on the basis of domestic and overseas research status and establishes relevant mathematical models at all levels. Then a Web GIS and SPSS WebAPP-based indices-issued system model is constructed. The relevant key techniques are analyzed, and the functions of the model are discussed. Otherwise, according to current conditions, the application of the system is conceived.",
        "keywords": [
            "real estate confidence index",
            "information-oriented",
            "real estate market",
            "web gis",
            "system modeling",
            "real time",
            "real estate",
            "demand and supply",
            "indexation",
            "mathematical model"
        ],
        "authors": [
            {
                "name": "Hongling Guo",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, Hong Kong Polytechnic University, Hong Kong, PR China"
            },
            {
                "name": "Qiping Shen",
                "org": "Department of Building and Real Estate, Hong Kong Polytechnic University, Hong Kong, PR China"
            },
            {
                "name": "Yaowu Wang",
                "org": "School of Management, Harbin Institute of Technology, Harbin, PR China"
            },
            {
                "name": "Yan Li",
                "org": "School of Science and Engineering on Communications, Harbin Institute of Technology, Harbin, PR China"
            }
        ],
        "venue": "International Journal of Project Management",
        "year": 2007
    },
    "LgzVS835": {
        "id": "LgzVS835",
        "title": "Optimizing construction planning schedules by virtual prototyping enabled resource analysis",
        "abstract": "The inherent uncertainty and complexity of construction work make construction planning a particularly difficult task for project managers due to the need to anticipate and visualize likely future events. Conventional computer-assisted technology can help but is often limited to the constructability issues involved. Virtual prototyping, however, offers an improved method through the visualization of construction activities by computer simulation \u2014 enabling a range of \u2018what-if\u2019 questions to be asked and their implications on the total project to be investigated. This paper describes the use of virtual prototyping to optimize construction planning schedules by analyzing resource allocation and planning with integrated construction models, resource models, construction planning schedules and site-layout plans. A real-life case study is presented that demonstrates the use of a virtual prototyping enabled resource analysis to reallocate space, logistic on access road and arrange tower cranes to achieve a 6-day floor construction cycle.",
        "keywords": [
            "construction planning schedule",
            "virtual prototyping",
            "resource analysis",
            "space"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Neo Chan",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Kowloon, Hong Kong"
            },
            {
                "name": "Ting Huang",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Kowloon, Hong Kong"
            },
            {
                "name": "H.L. Guo",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Kowloon, Hong Kong"
            },
            {
                "name": "Weisheng Lu",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Kowloon, Hong Kong"
            },
            {
                "name": "Martin Skitmore",
                "org": "School of Urban Development, Queensland University of Technology, QLD 4000, Australia"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2009
    },
    "hvmnmGl4": {
        "id": "hvmnmGl4",
        "title": "A knowledge-based system for automatic measurement of steel reinforcement",
        "abstract": "This paper presents a computer system, namely VHSTATION, for automatically recognizing and measuring steel reinforcement from vectorised structural drawings. This system utilizes rules extracted based on the feature of structural drawings to support the interpretation of drawing elements and the relationship between the elements. The paper presents the rules extracted for recognizing symbols and reinforcement steel. The use of the rules is illustrated with various examples. An innovative method, which is called the enhanced gravity field relationship method (EGFRM), is developed in order to recognize the information needed for calculating reinforcement steel. The system is fully implemented and commercially available.",
        "keywords": [
            "pattern recognition",
            "system architecture",
            "computer aided design",
            "knowledge based system"
        ],
        "authors": [
            {
                "name": "Shuhua Wang",
                "org": "State Key Laboratory of Novel Software Technology, Nanjing University, Nanjing, 210093, China"
            },
            {
                "name": "Yang Cao",
                "org": "Department of Building and Real Estate, Hong Kong Polytechnic University, Hong Kong, China"
            },
            {
                "name": "Ruo Yu Yang",
                "org": "State Key Laboratory of Novel Software Technology, Nanjing University, Nanjing, 210093, China"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, Hong Kong Polytechnic University, Hong Kong, China"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2002
    },
    "Dsl2vPu7": {
        "id": "Dsl2vPu7",
        "title": "Broadband services for residential and commercial tenants: a categorisation of current and future services and a survey on tenants needs in Sweden",
        "abstract": "The world is going through a rapid development of Internet and network-related technologies. The Swedish government's vision is, for example, that all private persons, firms and organisations have broadband in the speed of five megabit per second before 2005. Such developments mean that the market for the construction industry will expand. Most large and medium size contractors in Sweden work with drawing cables for broadband. Most companies in real estate offer or plan to offer broadband services to their tenants. The trend is that the technologies and the suppliers drive the development of broadband, not customers and the customers\u2019 needs. In this paper a global scanning of current and future services, delivered by broadband, which can be used in computer networks of the type local community system (LCS) developed by NCC and Ericsson is presented. Twenty-eight types of services are identified and are categorised in five major groups; information services, communication services, entertainment services, e-commerce services and telemetry services. In collaboration with NCC customers\u2019 needs on broadband services were investigated in a case study, Sundby Park. A questionnaire based on the types of services identified was sent to 144 residential tenants and 42 commercial tenants in the area. The study indicates that residential tenants are most interested in information services while commercial tenants are most interested in communication services. In total, the interest for broadband services is lower than expected. The reason could either be that the industries overestimate the tenants needs for broadband services or that the respondents do not have enough knowledge yet to fully understand the services.",
        "keywords": [
            "commercial tenants",
            "broadband services",
            "broadband",
            "residential tenants",
            "property-development",
            "computer network",
            "e commerce",
            "real estate",
            "type of service",
            "construction industry",
            "property development"
        ],
        "authors": [
            {
                "name": "Manne Aronsson",
                "org": "NCC AB, Gothenburg, Sweden"
            },
            {
                "name": "Daniel Thol\u00e9n",
                "org": "Ingemansson Technology AB, Gothenburg, Sweden"
            },
            {
                "name": "Per-Erik Josephson",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong"
            },
            {
                "name": "Stephen Kong",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong"
            }
        ],
        "venue": "Building and Environment",
        "year": 2003
    },
    "ukY2ETTa": {
        "id": "ukY2ETTa",
        "title": "Exploring quantitative methods for project location selection",
        "abstract": "This paper aims at exploring quantitative methods that are appropriate for project location selection. One of the major considerations of whether to undertake a construction project is to determine if the location is valuable for investment. Location selection may be simply based on past experience, rudimentary, \u201cgut-feeling\u201d, or a combination of them. Alternatively, it may involve scientific methods. The paper introduces both deterministic and dynamic approaches and presents some of the basic quantitative methods, including data envelopment analysis model and binary integer linear program models, serving as a base for both academics and practitioners. To expand the contribution of the paper, illustrative examples are given.",
        "keywords": [
            "location selection",
            "construction project",
            "quantitative method",
            "mathematical model",
            "scientific method",
            "data envelope analysis"
        ],
        "authors": [
            {
                "name": "Eddie W.L. Cheng",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hunghom, Kowloon, Hong Kong"
            }
        ],
        "venue": "Building and Environment",
        "year": 2004
    },
    "yKo9bDlK": {
        "id": "yKo9bDlK",
        "title": "Virtual Prototyping of innovative construction operations",
        "abstract": "The planning of construction operations is a complicated activity involving abstraction of construction activities from the drawings, choosing of suitable plants and falseworks, allocation of resources on site, planning of safe working place for labourers, and the scheduling of activities sequence. The increasing competition among contractors demands them to adopt innovative construction methods which have not been used or tested previously. It is not until the beginning of actual construction that the construction planner can realize the validity of his construction operations planning. The lack of tools for the construction planner to evaluate and validate his planning can result in incorrect construction plans which cause a lot of rework in the construction phase. Virtual Prototyping (VP) technology, which has been developed in the manufacturing industry, can provide a solution to the above problem. VP technology can simulate construction products, processes and resources in a virtual environment so that a construction project can be virtually constructed and the feasibility of a construction plan can be checked. This paper presents a case study of conducting the virtual prototyping of a building project. The outcomes of this case study, including the advantages and difficulties of using the VP technology in construction, are also discussed.",
        "keywords": [
            "Construction planning",
            "Experiment",
            "Virtual Prototyping"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": "Hong Kong Polytechnic University(Hong Kong Polytechnic University,The Hong Kong Polytechnic University),Hong Kong,China"
            },
            {
                "name": "Stephen Kong",
                "org": "Hong Kong Polytechnic University(Hong Kong Polytechnic University,The Hong Kong Polytechnic University),Hong Kong,China"
            },
            {
                "name": "Geoffrey Qiping Shen",
                "org": "Hong Kong Polytechnic University(Hong Kong Polytechnic University,The Hong Kong Polytechnic University),Hong Kong,China"
            },
            {
                "name": "Andrew N. Baldwin .",
                "org": "Hong Kong Polytechnic University(Hong Kong Polytechnic University,The Hong Kong Polytechnic University),Hong Kong,China"
            },
            {
                "name": "Zhiliang Ma",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            },
            {
                "name": "Peter E D Love",
                "org": "Edith Cowan University(Edith Cowan University),Bunbury,Australia"
            }
        ],
        "venue": "Queensland University of Technology Research Week International Conference, QUT Research Week 2005 - Conference Proceedings",
        "year": 2005
    },
    "ZclOMo3j": {
        "id": "ZclOMo3j",
        "title": "Computer-aided-construction-management, a new paradigm",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Conrad Tin-Cheung Wong",
                "org": "VHSoft Technologies Co. Ltd. F1 29-30, Chinachem Century Tower, 178 Gloucester Road, Wanchai, Hong Kong"
            },
            {
                "name": "Hubert Mak",
                "org": "VHSoft Technologies Co. Ltd. F1 29-30, Chinachem Century Tower, 178 Gloucester Road, Wanchai, Hong Kong"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong"
            }
        ],
        "venue": "Advances in Building Technology",
        "year": 2002
    },
    "v6I7PyFD": {
        "id": "v6I7PyFD",
        "title": "A computer-aided decision support system for assessing a contractor's competitiveness",
        "abstract": "This paper presents a computer-aided decision support system for assessing a contractor's competitiveness. Measures of competitiveness are employed to describe a contractor's strengths and weaknesses, thus to assist project clients in identifying proper contractors at the pre-qualification stage. The identification of a contractor's weakness can also help the contractor adopt proper measures to improve its competitiveness. Based on a competitiveness scoring model, a Windows-standard Decision Support System Contractor's Competitiveness Assessment Scoring System (C-CASS) was developed in this study. Case studies in a simulated environment are used to demonstrate the application of this system.",
        "keywords": [
            "construction",
            "contractor competitiveness",
            "decision support system",
            "pre-qualification",
            "c-cass"
        ],
        "authors": [
            {
                "name": "Liyin Y Shen",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Kowloon, Hong Kong, China"
            },
            {
                "name": "Weisheng Lu",
                "org": "Chongqing University, China"
            },
            {
                "name": "Qiping Shen",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Kowloon, Hong Kong, China"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Kowloon, Hong Kong, China"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2003
    },
    "0TeN1lwY": {
        "id": "0TeN1lwY",
        "title": "Practical framework for measuring performance of international construction firms",
        "abstract": "The internationalization of construction companies has become of significant interest as the global construction market continues to be integrated into a more competitive and turbulent business environment. However, due to the complicated and multifaceted nature of international business and performance, there is as yet no consensus on how to evaluate the performance of international construction firms (ICFs). The purpose of this paper, therefore, is to develop a practical framework for measuring the performance of ICFs. Based on the balanced scorecard (BSC), a framework with detailed measures is developed, investigated, and tested using a three-step research design. In the first step, 27 measures under six dimensions (financial, market, customer, internal business processes, stakeholders, and learning and growth) are determined by literature review, interviews with academics, and seminar discussions. Subsequently, a questionnaire survey is conducted to investigate weights of these 27 performance measures. The questionnaire survey also supports the importance of measuring intangible aspects of international construction performance from the practitioner's viewpoint. Additionally, a case study is described to test the framework's robustness and usefulness. This is achieved by benchmarking the performance of a Chinese ICF with nine other counterparts worldwide. It is found that the framework provides an effective basis for benchmarking ICFs to effectively monitor their performance and support the development of strategies for improved competitiveness in the international arena. This paper is the first attempt to present a balanced and practically tested framework for evaluating the performance of ICFs. It contributes to the practice of performance measurement and related internationalization in the construction industry in general. \u00a9 2013 American Society of Civil Engineers.",
        "keywords": [
            "balanced scorecard",
            "benchmarking",
            "construction firm",
            "international construction",
            "internationalization",
            "organizational issues",
            "performance measurement",
            "benchmark",
            "measurement"
        ],
        "authors": [
            {
                "name": "Zhigang Jin",
                "org": "Sichuan University(Sichuan University),Chengdu,China"
            },
            {
                "name": "Fei Deng",
                "org": "UCL(University College London,^ University College),London,United Kingdom"
            },
            {
                "name": "Heng Li",
                "org": "Hong Kong Polytechnic University(Hong Kong Polytechnic University,The Hong Kong Polytechnic University),Hong Kong,China"
            },
            {
                "name": "Martin Skitmore",
                "org": "Queensland University of Technology(Queensland University of Technology),Brisbane,Australia"
            }
        ],
        "venue": "Journal of Construction Engineering and Management",
        "year": 2013
    },
    "hCWZ7205": {
        "id": "hCWZ7205",
        "title": "Discussion of \u201cWaste-Based Management in Residential Construction\u201d by Jing Zhang, Danelle L. Eastham, and Leonhard E. Bernold",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Zhen Chen",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Andrew N. Baldwin",
                "org": ""
            }
        ],
        "venue": "Journal of Construction Engineering and Management-asce",
        "year": 2006
    },
    "loyUnOZ2": {
        "id": "loyUnOZ2",
        "title": "Two resource dispatching rules for modeling human decisions in simulation",
        "abstract": "In an actual construction operation, a site manager usually has to make real-time decisions on dispatching shared resources to competing activities. To ensure a valid simulation of the operation on a computer, properly modeling how such decisions are made is crucial. This article presents two rules for guiding resource dispatching during simulation, addressed as objective function-based and control variable-based rules. The objective function-based rule defines an objective function for each activity which is competing for the resource; and an activity is selected if it has the optimum (either minimum or maximum) objective function value. A control variable is used to describe an indicator of the status of a simulation. Through structured conditional statements, it is used to control whether an activity shall or shall not be selected to receive a releasing resource according to the updated value of the control variable at the time when the decision is made. The algorithms are implemented in the ABC simulation system. A case study is presented to illustrate the usage and advantage of the presented rules. The results show an improved process production, and more stable and balanced operational behavior of the process after the real-time human decisions are modeled in the simulation. Through the animation function, a user can visualize on the screen that the decisions are dynamically made corresponding to the status of the simulation in the manner similar to what a site manager would make on the site.",
        "keywords": [
            "site management",
            "real-time decision-making",
            "resource allocation",
            "dispatching rules",
            "construction operation",
            "modeling and simulation",
            "objective function",
            "real time"
        ],
        "authors": [
            {
                "name": "Jonathan Jingsheng Shi",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong"
            },
            {
                "name": "Hong Zhang",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong"
            }
        ],
        "venue": "International Journal of Project Management",
        "year": 2005
    },
    "ESVAXvQz": {
        "id": "ESVAXvQz",
        "title": "Construction virtual prototyping: a survey of use",
        "abstract": "",
        "keywords": [
            "questionnaire survey",
            "design methodology",
            "construction industry",
            "communication",
            "prototypes",
            "building information model",
            "simulation",
            "project planning"
        ],
        "authors": [
            {
                "name": "Ting Huang",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Hongling Guo",
                "org": ""
            },
            {
                "name": "Neo Chan",
                "org": ""
            },
            {
                "name": "Stephen Kong",
                "org": ""
            },
            {
                "name": "Greg Chan",
                "org": ""
            },
            {
                "name": "Martin Skitmore",
                "org": ""
            }
        ],
        "venue": "Construction Innovation: Information, Process, Management",
        "year": 2009
    },
    "I30kNV4S": {
        "id": "I30kNV4S",
        "title": "Rework: a symptom of a dysfunctional supply-chain",
        "abstract": "This paper describes and presents findings from a detailed case study that sought to acquire an in-depth understanding of \u2018why\u2019 and \u2018how\u2019 rework occurred the way it did in a structural steel supply-chain. The findings from the case study indicate that the cause of rework was primarily attributable to the sequential nature of the supply-chain, which resulted in poor communication and decision-making being experienced. This was found to be further exacerbated by the absence of a quality focus during the design process, which resulted in the supply-chain becoming dysfunctional inasmuch as rework emerged downstream in the production process. A conceptual model for improving the effectiveness of a supply-chain and thus minimising the incidence of rework is presented and discussed.",
        "keywords": [
            "customer satisfaction",
            "quality",
            "rework",
            "information flow",
            "supply-chain",
            "production process",
            "supply chain",
            "design process",
            "conceptual model"
        ],
        "authors": [
            {
                "name": "Peter E.D. Love",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, Hong Kong"
            },
            {
                "name": "Purnendu Mandal",
                "org": "School of Engineering and Technology, Deakin University, Geelong, Victoria 3217, Australia"
            }
        ],
        "venue": "European Journal of Purchasing and Supply Management",
        "year": 1999
    },
    "nygWb0hd": {
        "id": "nygWb0hd",
        "title": "INCITE 2004",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Peter Brandon",
                "org": "Office of Strategic Development, The University of Salford, UK"
            },
            {
                "name": "Geoffrey Q.P. Shen",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2005
    },
    "DHJwjqtb": {
        "id": "DHJwjqtb",
        "title": "Discussion of \u201cRisks in Chinese Construction Market\u2014Contractors\u2019 Perspective\u201d by Dongping Fang, Mingen Li, Patrick Sik-wah Fong, and Liyin Shen",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Zhen Chen",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            }
        ],
        "venue": "Journal of Construction Engineering and Management-asce",
        "year": 2006
    },
    "XzFgdUYZ": {
        "id": "XzFgdUYZ",
        "title": "Evaluating the system intelligence of the intelligent building systems",
        "abstract": "This paper describes the development of an analytical model for computing the system intelligence score ( SIS ) of key building control systems in the intelligent building. The models presented in this paper applied the system intelligence theory, and the conceptual analytical framework developed in Part 1 [J.K.W. Wong, H. Li, J. Lai, Evaluating the system intelligence of the intelligent building systems \u2014 Part 1: Development of key intelligent indicators and assessment approaches, (submitted and under review)]. Two multi-criteria decision making (MCDM) approaches, the analytic hierarchy process (AHP) and analytic network process (ANP), were employed in this study to evaluate the system intelligence of the intelligent building systems. AHP was utilized to determine the relative importance of the intelligent attributes and indicators in the model, while the ANP supermatrix was employed to examine the interdependence between the intelligent attributes and the operational benefits of the intelligent building system. A comparison of findings obtained from AHP and ANP approaches indicated that most of the values of the intelligent indicators changed. The interdependence between operational goals/benefits and the intelligent attributes modified the original ratings obtained from AHP. The ANP approach allows inclusive decision making on the system intelligence. Such approach not only examines the intelligent properties of intelligent building systems, but also considers the operational benefits brought by intelligent technologies. The paper uses the integrated building management system (IBMS) as an illustrative example to present a framework. The proposed analytical model is illustrated with an example to demonstrate its assessment procedures and test its effectiveness in application.",
        "keywords": [
            "analytic network process (anp)",
            "intelligent building system (ibs)",
            "intelligent indicators (iis)",
            "analytic hierarchy process (ahp)",
            "system intelligence score (sis)",
            "intelligent building systems (ibss)",
            "multi-criteria decision-making (mcdm)",
            "intelligent building",
            "control system",
            "decision models",
            "analytic hierarchy process",
            "analytic network process",
            "management system",
            "decision maker"
        ],
        "authors": [
            {
                "name": "Johnny Wong",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hunghom, Kowloon, Hong Kong"
            },
            {
                "name": "Jenkin Lai",
                "org": "Facilities Management, Pacific Century Premium Developments Ltd., Hong Kong"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2008
    },
    "7S13i3Bn": {
        "id": "7S13i3Bn",
        "title": "Semiautomated Detection of Design Errors in 2D Drawings Using 3D Reconstruction",
        "abstract": "",
        "keywords": [
            "3d reconstruction"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Yang Cao",
                "org": ""
            },
            {
                "name": "Ming Lu",
                "org": ""
            }
        ],
        "venue": "Computer-aided Civil and Infrastructure Engineering",
        "year": 2004
    },
    "SYdI7qus": {
        "id": "SYdI7qus",
        "title": "Improving agent-based negotiation efficiency in construction supply chains: A relative entropy method",
        "abstract": "This research presents a relative entropy method for improving agent-based negotiation efficiency (REANE) in a construction supply chain. REANE provides a path forward to help negotiators reach an acceptable solution when other methods fail; the key insight is the use of relative entropy to measure the relative degree of consensus among parties and hence minimize necessary compromises. An illustrative example is presented to show the application of REANE. The REANE method aggregates the preference information of negotiators in CSC twice. First, a compromise group preference order is ascertained using preference information, which is newly provided by negotiators, and compromise preference information (formed previously in the agent-based auto-negotiation process). Second, group preferences are aggregated by employing a relative entropy model, which is established based on entropy theory, while, considering the multiple attributes of negotiation in a construction supply chain. The method of REANE fulfills the necessary requirement of group decision-making, i.e., maximizing the preference consistency of decision-making groups and minimizing the utility gaps between every negotiator's preference and the group's preference.",
        "keywords": [
            "construction supply chain",
            "agent-based negotiation",
            "negotiation efficiency",
            "relative entropy",
            "group decision making"
        ],
        "authors": [
            {
                "name": "Xiaolong Xue",
                "org": "Department of Construction and Real Estate, School of Management, Harbin Institute of Technology, Harbin 150001, China"
            },
            {
                "name": "Qiping Shen",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China"
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "William J. O'Brien",
                "org": "Department of Civil, Architectural, and Environmental Engineering, University of Texas at Austin, USA"
            },
            {
                "name": "Zhaomin Ren",
                "org": "Division of Built Environment, Faculty of Advanced Technology, University of Glamorgan, UK"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2009
    },
    "9ZwHEg6d": {
        "id": "9ZwHEg6d",
        "title": "The Study of Chinese Construction Enterprises\u2019 Internationalization Performance Evaluation System",
        "abstract": "Accompany with China\u2019s economic dramatic growth, construction industry of china has experienced huge leverage. Chinese construction enterprise, one of the main participants in the industry, has also received a golden chance of development and expansion. There are more and more enterprises have gone out of the national boundary to pursue further growth and prosperity in the international market. In order to help their expansion in the international market more efficiently, an evaluation framework of construction enterprise\u2019s international performance was formulated on the basis of Balance Scorecard. Then, a case study was conducted to illustrate the application of evaluation system. In the case study, a Chinese construction firm and other four top international construction firms were selected to carry out comparison analysis. The findings provide an insight into the weakness that influence international development of Chinese construction enterprises and also help practitioners to timely adjust their strategy of international operation to ensure international business success.",
        "keywords": [
            "Performance Evaluation",
            "Internationalization",
            "Construction Enterprise",
            "China"
        ],
        "authors": [
            {
                "name": "Li Heng",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong, China"
            },
            {
                "name": "Jin Zhigang",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong, China"
            }
        ],
        "venue": "Journal of Information Technology in Civil Engineering and Architecture",
        "year": 2010
    },
    "qAJVfkxO": {
        "id": "qAJVfkxO",
        "title": "Automatic recognition of tables in construction tender documents",
        "abstract": "The construction industry can gain much benefit from automation, especially in automatic document generation and recognition. In this paper, an automatic system for recognizing tables in construction tender documents is introduced. Tender documents contain a special kind of forms. The object-oriented attributed relationship graph (OO-ARG) is introduced to be the representation scheme for structuring the information contained in forms. The OO-ARG representation scheme is the core of the computer system for recognizing and interpreting tender documents. The system consists of two main modules: table modeler and table reader. The table modeler assists users to construct form models, and the table reader recognizes the input tables from the model database and re-generates electronic tables. Experimental results indicate that the system is efficient and applicable in recognizing construction tender documents.",
        "keywords": [
            "table model",
            "attributed relationship graph",
            "construction tender document",
            "form recognition",
            "object oriented",
            "construction industry"
        ],
        "authors": [
            {
                "name": "Yang Cao",
                "org": "Department of Building and Real Estate, Hong Kong Polytechnic University, Hong Kong, China"
            },
            {
                "name": "Shuhua Wang",
                "org": "State Key Laboratory of Novel Software Technology, Nanjing University, Nanjing 210093, China"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, Hong Kong Polytechnic University, Hong Kong, China"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2002
    },
    "0gZHRXX2": {
        "id": "0gZHRXX2",
        "title": "Construction, application and validation of selection evaluation model (SEM) for intelligent HVAC control system",
        "abstract": "Design teams are confronted with the quandary of choosing apposite building control systems to suit the needs of particular intelligent building projects, due to the availability of innumerable \u2018intelligent\u2019 building products and a dearth of inclusive evaluation tools. This paper is organised to develop a model for facilitating the selection evaluation for intelligent HVAC control systems for commercial intelligent buildings. To achieve these objectives, systematic research activities have been conducted to first develop, test and refine the general conceptual model using consecutive surveys; then, to convert the developed conceptual framework into a practical model; and, finally, to evaluate the effectiveness of the model by means of expert validation. The results of the surveys are that \u2018 total energy use \u2019 is perceived as the top selection criterion, followed by the \u2018 system reliability and stability \u2019, \u2018 operating and maintenance costs \u2019, and \u2018 control of indoor humidity and temperature \u2019. This research not only presents a systematic and structured approach to evaluate candidate intelligent HVAC control system against the critical selection criteria (CSC), but it also suggests a benchmark for the selection of one control system candidate against another.",
        "keywords": [
            "model",
            "hvac",
            "intelligent building",
            "selection evaluation",
            "building control system"
        ],
        "authors": [
            {
                "name": "Johnny K.W. Wong",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2010
    },
    "msBoZLL2": {
        "id": "msBoZLL2",
        "title": "Virtual prototyping of innovative construction operations",
        "abstract": "The planning of construction operations is a complicated activity involving abstraction of construction activities from the drawings, choosing of suitable plants and falseworks, allocation of resources on site, planning of safe working place for labourers, and the scheduling of activities sequence. The increasing competition among contractors demands them to adopt innovative construction methods which have not been used or tested previously. It is not until the beginning of actual construction that the construction planner can realize the validity of his construction operations planning. The lack of tools for the construction planner to evaluate and validate his planning can result in incorrect construction plans which cause a lot of rework in the construction phase. Virtual Prototyping (VP) technology, which has been developed in the manufacturing industry, can provide a solution to the above problem. VP technology can simulate construction products, processes and resources in a virtual environment so that a construction project can be virtually constructed and the feasibility of a construction plan can be checked. This paper presents a case study of conducting the virtual prototyping of a building project. The outcomes of this case study, including the advantages and difficulties of using the VP technology in construction, are also discussed.",
        "keywords": [
            "Construction Planning",
            "Experiment",
            "Virtual Prototyping"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": "Hong Kong Polytechnic University(Hong Kong Polytechnic University,The Hong Kong Polytechnic University),Hong Kong,China"
            },
            {
                "name": "Stephen Kong",
                "org": "Hong Kong Polytechnic University(Hong Kong Polytechnic University,The Hong Kong Polytechnic University),Hong Kong,China"
            },
            {
                "name": "Geoffrey Qiping Shen",
                "org": "Hong Kong Polytechnic University(Hong Kong Polytechnic University,The Hong Kong Polytechnic University),Hong Kong,China"
            },
            {
                "name": "Andrew N. Baldwin .",
                "org": "Hong Kong Polytechnic University(Hong Kong Polytechnic University,The Hong Kong Polytechnic University),Hong Kong,China"
            },
            {
                "name": "Zhiliang Ma",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            },
            {
                "name": "Peter E D Love",
                "org": "Edith Cowan University(Edith Cowan University),Bunbury,Australia"
            }
        ],
        "venue": "Queensland University of Technology Research Week International Conference, QUT Research Week 2005 - Conference Proceedings",
        "year": 2005
    },
    "vdraqYsL": {
        "id": "vdraqYsL",
        "title": "Building information modeling and changing construction practices",
        "abstract": "",
        "keywords": [
            "construction industry",
            "building information model"
        ],
        "authors": [
            {
                "name": "Wilson W.S. Lu",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": "Construction Informatics, Dept. of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2011
    },
    "ZmURdhi5": {
        "id": "ZmURdhi5",
        "title": "The learning organisation: toward a paradigm for mutually beneficial strategic construction alliances",
        "abstract": "Strategic alliances are becoming an important means of survival for managing construction organisations. Such alliances are a compromise between organisations doing business in isolation and in mutual partnership with another organisation(s). The key to competitive advantage and improving customer satisfaction lies in the ability of organisations to form learning alliances ; these being strategic partnerships based on a business environment that encourages mutual (and reflective) learning between partners. Well-designed, successful alliances enhance co-operation and a high level of trust and commitment. A learning framework is presented to foster successful co-operative strategic alliances between construction organisations. A case study is highlighted based on Rameses Associates and Lloyds TSB Insurance of the UK, to illustrate the advantages of the thesis proffered.",
        "keywords": [
            "learning organisation",
            "organisational management",
            "co-operation",
            "strategic alliances",
            "collaboration",
            "competitive advantage",
            "reflective learning",
            "customer satisfaction"
        ],
        "authors": [
            {
                "name": "Gary D. Holt",
                "org": ""
            },
            {
                "name": "Peter E.D. Love",
                "org": "School of Architecture and Building, Deakin University, Victoria, Australia"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong"
            }
        ],
        "venue": "International Journal of Project Management",
        "year": 2000
    },
    "ZfG54SzA": {
        "id": "ZfG54SzA",
        "title": "VP-based safety management in large-scale construction projects: A conceptual framework",
        "abstract": "Construction safety is a serious problem in the construction industry worldwide, especially in large-scale construction projects. In order to improve the safety management performance, through the identification of the key factors that cause accidents, this research develops a conceptual framework of adopting virtual prototyping (VP) technology to aid in construction safety management. It consists of three components: modelling and simulation, the identification of unsafe factors, and safety training. A real-life case study is presented to demonstrate how to implement the VP-based safety management platform and evaluate its feasibility and validity. It is shown that the VP-based safety management platform can effectively aid in safety management and improve the safety performance of construction projects. \u00a9 2012 Elsevier B.V. All rights reserved.",
        "keywords": [
            "large-scale construction projects",
            "safety management",
            "safety performance",
            "the construction industry",
            "virtual prototyping"
        ],
        "authors": [
            {
                "name": "Hongfend Guo",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            },
            {
                "name": "Heng Li",
                "org": "Hong Kong Polytechnic University(Hong Kong Polytechnic University,The Hong Kong Polytechnic University),Hong Kong,China"
            },
            {
                "name": "Vera Li",
                "org": "Hong Kong Polytechnic University(Hong Kong Polytechnic University,The Hong Kong Polytechnic University),Hong Kong,China"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2013
    },
    "U5vgoGpN": {
        "id": "U5vgoGpN",
        "title": "Information management system for market analysis of real estate development projects",
        "abstract": "A information management system was developed for market analysis of real estate development projects.The system is based on current status of market analyses using geographic information systems(GIS),network analysis,and database technologies.The opinions of field experts were obtained for the results from a prototype system.The system can assist market analyses of real estate development projects,reduce costs,and improve working efficiency.",
        "keywords": [
            "real estate development projects",
            "geographic information system(GIS)",
            "market analysis",
            "database"
        ],
        "authors": [
            {
                "name": "MA Zhiliang",
                "org": "Department of Civil Engineering,Tsinghua University,Beijing ,China"
            },
            {
                "name": "FU Siyuan",
                "org": "Department of Civil Engineering,Tsinghua University,Beijing ,China"
            },
            {
                "name": "LI Heng",
                "org": "Department of Building and Real Estate,The Hong Kong Polytechnic University,Hong Kong,China"
            },
            {
                "name": "LI Yonghe",
                "org": "Department of Civil Engineering,Tsinghua University,Beijing ,China"
            }
        ],
        "venue": "Journal of Tsinghua University(Science and Technology)",
        "year": 2007
    },
    "grcg8uNJ": {
        "id": "grcg8uNJ",
        "title": "Does the Effort Meet the Challenge in Promoting Low-Carbon City?-A Perspective of Global Practice.",
        "abstract": "Global warming caused by carbon emissions has been recognized as a challenge to human sustainable development, and low-carbon city development is widely considered as an effective strategy to address this challenge. Numerous emission reduction measures have been implemented, and considerable efforts have been devoted in promoting low-carbon city. This paper examines whether sufficient efforts have been paid to these typical emission sectors, including Building, Industry, Energy Transformation, and Transportation by referring to the shared responsibility of each sector. The shared responsibility of individual emission sector is calculated by applying energy consumption data in 2014 World Energy Balance. The efforts contributed in emission reduction by each sector are examined by analyzing the low-carbon city work plans of 24 representative sample cities, which are selected globally. The research results demonstrate that sufficient emission reduction efforts have been paid in the Building sector and Transportation sector. But the Industry sector and Energy Transformation sector are less-attended in addressing emission reduction. The reason for the sufficient efforts paid in the Building sector and Transportation sector is considered as that the efforts for emission reduction in these two sectors can bring more co-benefits. However, emission reduction in Industrial sector is generally considered to have the effects of holding back economic growth, and the emission reduction in the sector of Energy Transformation will need enormous investment for advanced technologies. Policy for emission reduction in the Industry sector and Energy Transformation sector is indispensable to promote low-carbon city. This study appeals that (1) low-carbon city can be effectively implemented only if carbon reduction policy is adopted to all industrial activities; (2) multiple channels of financial resources should be established to support cities to mitigate carbon emissions in Industry sector; (3) cooperation on the development of clean energy technology between cities should be promoted; and (4) efforts should be paid to reduce carbon emission from using traditional energy transformation equipment by improving their efficiency.",
        "keywords": [
            "carbon emissions",
            "climate change",
            "emission reduction policy",
            "global perspective",
            "low-carbon city",
            "sustainability"
        ],
        "authors": [
            {
                "name": "Yingli Lou",
                "org": "School of Construction Management and Real Estate, International Research Center for Sustainable Built Environment, Chongqing University, Chongqing 400045, China. 20160302057t@cqu.edu.cn."
            },
            {
                "name": "Liyin Shen",
                "org": "School of Construction Management and Real Estate, International Research Center for Sustainable Built Environment, Chongqing University, Chongqing 400045, China. shenliyincqu@163.com."
            },
            {
                "name": "Zhenhua Huang",
                "org": "School of Construction Management and Real Estate, International Research Center for Sustainable Built Environment, Chongqing University, Chongqing 400045, China. 20150302017t@cqu.edu.cn."
            },
            {
                "name": "Ya Wu",
                "org": "School of Construction Management and Real Estate, International Research Center for Sustainable Built Environment, Chongqing University, Chongqing 400045, China. mswuya@126.com."
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, Hong Kong Polytechnic University, Hong Kong 999077, China. bshengli@polyu.edu.hk."
            },
            {
                "name": "Guijun Li",
                "org": "Center of International Cooperation Research, Central University of Finance and Economics, Beijing 100081, China. ligj@cufe.edu.cn."
            }
        ],
        "venue": "International journal of environmental research and public health",
        "year": 2018
    },
    "BaMOJdpW": {
        "id": "BaMOJdpW",
        "title": "Why small towns can not share the benefits of urbanization in China",
        "abstract": "Abstract   The urbanization process over last several decades in China has brought benefits in multiple dimensions throughout the country. However, it appears that the benefits shared by small towns is very limited, and this is particular the case in Southwest China. This paper examines holistically the barriers against benefit-sharing by small towns in the urbanization process in China. Theory of Constraints (TOC) has been applied in this study in producing a holistic barrier-framework for studying the significance and performance of individual barriers. 21 case townships are selected in Southwest China for field surveys, including interview discussions, on-site visits and data collections. The content analysis and Likert scale scoring approach are used to convert the survey data to score values. Those significant barriers are discussed in depth by examining practical cases extracted from the field surveys. The study presents the most significant barriers which limit the benefit-sharing by small towns in Southwest China, such as lack of talents, limited financing channels, loss of labor-force population, lack of infrastructure construction, mono-industry structure, low level management ability, and restricted jurisdiction power. The findings from this study provide valuable references to search for effective approaches for promoting the development of small towns and contributing to the healthy and sustainable urbanization process in China.",
        "keywords": "",
        "authors": [
            {
                "name": "Liyin Shen",
                "org": "School of Construction Management and Real Estate, Chongqing University, Chongqing, PR China"
            },
            {
                "name": "Yitian Ren",
                "org": "School of Construction Management and Real Estate, Chongqing University, Chongqing, PR China"
            },
            {
                "name": "Ning Xiong",
                "org": "School of Construction Management and Real Estate, Chongqing University, Chongqing, PR China"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Kowloon, Hong Kong"
            },
            {
                "name": "Yang Chen",
                "org": "School of Construction Management and Real Estate, Chongqing University, Chongqing, PR China"
            }
        ],
        "venue": "Journal of Cleaner Production",
        "year": 2018
    },
    "HbgfgYtw": {
        "id": "HbgfgYtw",
        "title": "What Is the Efficiency of Fast Urbanization? A China Study",
        "abstract": "Urbanization is commonly described as the process of population flow from rural to urban areas. As the largest developing country, China has experienced an unprecedentedly fast and large urbanization process since 1980s, which will continue for the coming future. The immense scale of the process has brought multidimensional benefits across all sectors in the country, yet also consumed a vast amount of resources and caused various types of environmental problems. The conflict between limited resources and an unstoppable urbanization process has become a pressing issue, which presents the urgent need for efficiency pursuance in the process of urbanization in order to ensure sustainable urban development. It is considered that the improvement of urbanization efficiency in large developing countries such as China has great implications for global sustainability. There is little existing study conducted to understand what efficiency achieved in the current fast urban development era in China. This study investigates the urbanization efficiency and its changes in the contemporary China. A set of input-output indicators are employed for analyzing the efficiency, in which both desirable and undesirable outputs are considered. The Super-efficiency Slack-based Measure (SBM) model and DEA-based Malmquist Production Index (MPI) are adopted collectively for conducting data analysis. The research is conducted at provincial level in China and the data collected for analysis are from 30 provinces for the period of 2006\u20132015. The results from this study show that the overall urbanization efficiency in China during the surveyed period is low, although certain improvement has been achieved. The difference between good and poor performers is considerable. In general, those provinces with better social and economic background have better urbanization efficiency performance. East China is much better than the rest of China, whilst Southwest region has the poorest performance.",
        "keywords": "",
        "authors": [
            {
                "name": "Yitian Ren",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Liyin Shen",
                "org": ""
            },
            {
                "name": "Yu Zhang",
                "org": ""
            },
            {
                "name": "Yang Chen",
                "org": ""
            },
            {
                "name": "Jinhuan Wang",
                "org": ""
            }
        ],
        "venue": "Sustainability",
        "year": 2018
    },
    "kKgQ07B0": {
        "id": "kKgQ07B0",
        "title": "Development orientations for attracting investments \u2013 A perspective of less-developed townships in China",
        "abstract": "Abstract   Investment attraction by adopting adequate development orientations is perceived as effective method for promoting social and economic development in those less developed areas or regions such as the mountainous townships in Southwest China. Investments will not be attracted or utilized effectively if the development orientation is positioned improperly. Existing studies do not provide methods for helping these townships define proper development orientations. This paper presents a decision-making method called  matching coefficient model  for supporting these less-developed townships to identify suitable development orientations in order to attract effective investments. The application of the method is demonstrated by a sample of 20 townships located in Southwest China. Research data employed are collected through on-spot investigations and semi-structured interviews with the officials in these sample townships. The research reveals that the existing development orientations adopted in many less-developed Chinese townships do not match the resources endowment they possess, thus limited investment has been attracted. The study finds that agritourism business is most suitable for application in these townships in order to attract effective external investments, and that strategic emerging industry seems not suitable. The research results provide valuable reference for township governments to design development orientations and adopt measures towards effective investment attraction.",
        "keywords": "",
        "authors": [
            {
                "name": "Liyin Shen",
                "org": "School of Construction Management and Real Estate, Chongqing University, Chongqing, PR China"
            },
            {
                "name": "Yang Chen",
                "org": "School of Construction Management and Real Estate, Chongqing University, Chongqing, PR China"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Kowloon, Hong Kong"
            },
            {
                "name": "Xiaoxuan Wei",
                "org": "School of Construction Management and Real Estate, Chongqing University, Chongqing, PR China"
            },
            {
                "name": "Yitian Ren",
                "org": "School of Construction Management and Real Estate, Chongqing University, Chongqing, PR China"
            }
        ],
        "venue": "Cities",
        "year": 2018
    },
    "dJOe3ePL": {
        "id": "dJOe3ePL",
        "title": "System reliability under prescribed marginals and correlations: Are we correct about the effect of correlations?",
        "abstract": "Many reliability problems involve correlated random variables. However, the probabilistic specification of random variables is commonly given in terms of marginals and correlations, which is actually incomplete because the data dependency needed for distribution modeling is not characterized. The implicitly assumed Gaussian dependence structure is not necessarily true and may bias the reliability result. To investigate the effect of correlations on system reliability under non-Gaussian dependence structures, a general approach to the probability distribution model construction based on the pair-copula decomposition is proposed. Numerical examples have highlighted the importance of dependence modeling in system reliability since large deviation in failure probabilities under different dependencies is observed. The method for identifying the best fit data dependency from data is later provided and illustrated with a retaining wall. It is demonstrated that the reliability result can be accurately estimated if the qualitative dependence structure is complemented to the available quantitative statistical information.",
        "keywords": "",
        "authors": [
            {
                "name": "Fan Wang",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Kowloon, Hong Kong"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Kowloon, Hong Kong"
            }
        ],
        "venue": "Rel. Eng. & Sys. Safety",
        "year": 2018
    },
    "R7PR3g5k": {
        "id": "R7PR3g5k",
        "title": "Stochastic response surface method for reliability problems involving correlated multivariates with non-Gaussian dependence structure: Analysis under incomplete probability information",
        "abstract": "Abstract   This paper aims to provide a stochastic response surface method (SRSM) that can consider non-Gaussian dependent random variables under incomplete probability information. The Rosenblatt transformation is adopted to map the random variables from the original space into the mutually independent standard normal space for the stochastic surrogate model development. The multivariate joint distribution is reconstructed by the pair-copula decomposition approach, in which the pair-copula parameters are retrieved from the incomplete probability information. The proposed method is illustrated in a tunnel excavation example. Three different dependence structures characterized by normal copulas, Frank copulas, and hybrid copulas are respectively investigated to demonstrate the effect of dependence structure on the reliability results. The results show that the widely used Nataf transformation is actually a special case of the proposed method if all pair-copulas are normal copulas. The effect of conditioning order is also examined. This study provides a new insight into the SRSM-based reliability analysis from the copula viewpoint and extends the application of SRSM under incomplete probability information.",
        "keywords": "",
        "authors": [
            {
                "name": "Fan Wang",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Kowloon, Hong Kong"
            },
            {
                "name": "Fan Wang",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Kowloon, Hong Kong"
            },
            {
                "name": "Fan Wang",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Kowloon, Hong Kong"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Kowloon, Hong Kong"
            }
        ],
        "venue": "Computers and Geotechnics",
        "year": 2017
    },
    "iZ9jr0Xk": {
        "id": "iZ9jr0Xk",
        "title": "Subset simulation for non-Gaussian dependent random variables given incomplete probability information",
        "abstract": "Abstract   Reliability analysis under incomplete probability information is a challenging task. This paper focuses on the extension of the subset simulation (SS), an efficient reliability approach, to the modeling of any dependent random variables under incomplete probability information. The Nataf transformation is commonly adopted to generate correlated random variables given marginal distributions and correlations; however, it inherently assumes a Gaussian dependence structure. In contrast, the Rosenblatt transformation can be used to generate correlated random variables with any dependence structure; however, the joint probability information must be known. To remove the limitation, the vine copula approach, which is highly flexible in dependence modeling, is used to reconstruct the joint probability information from the prescribed marginal distributions and correlations. The copula parameters in the vine structure are retrieved using an efficient approximation method. Three copula cases including the Gaussian and non-Gaussian dependence structures are investigated by applying the proposed method to a numerical example. The failure probabilities and the effects of the uncertain parameters correspond to different cases are compared, which aims to provide insights into the impact of the dependence structure on the SS results when only the incomplete probability information is given.",
        "keywords": "",
        "authors": [
            {
                "name": "Fan Wang",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Kowloon, Hong Kong"
            },
            {
                "name": "Fan Wang",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Kowloon, Hong Kong"
            },
            {
                "name": "Fan Wang",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Kowloon, Hong Kong"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Kowloon, Hong Kong"
            }
        ],
        "venue": "Structural Safety",
        "year": 2017
    },
    "NaPOuXXF": {
        "id": "NaPOuXXF",
        "title": "Towards reliability evaluation involving correlated multivariates under incomplete probability information: A reconstructed joint probability distribution for isoprobabilistic transformation",
        "abstract": "Abstract   Reliability evaluation under incomplete probability information (prescribed marginal distributions and correlation coefficients) is a challenging task. The widely used Nataf transformation inherently assumes a normal copula for dependence modeling, which can be inappropriate in some cases. This paper aims to provide a more general isoprobabilistic transformation method for reliability evaluations under incomplete probability information. To this end, the joint probability distribution is represented using the pair-copula decomposition approach, which is highly flexible in dependence modeling. The desired pair-copula parameters are retrieved from the incomplete probability information by a simulation-based method. Finally, based on the reconstructed joint probability distribution, the Rosenblatt\u2019s transformation is adopted for the subsequent reliability evaluation. The proposed method is illustrated in a tunnel excavation reliability problem. Several dependence structures characterized by different pair-copulas are investigated to provide insights into the effect of copula selection on reliability results.",
        "keywords": "",
        "authors": [
            {
                "name": "Fan Wang",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Kowloon, Hong Kong"
            },
            {
                "name": "Fan Wang",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Kowloon, Hong Kong"
            },
            {
                "name": "Fan Wang",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Kowloon, Hong Kong"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Kowloon, Hong Kong"
            }
        ],
        "venue": "Structural Safety",
        "year": 2017
    },
    "b9rCuHsK": {
        "id": "b9rCuHsK",
        "title": "The role of copulas in random fields: Characterization and application",
        "abstract": "Abstract   The spatial fluctuation of material properties is commonly modeled using random fields. However, descriptions of random fields in terms of marginal distributions and correlation structure are actually incomplete. The copulas that specify the dependence structure underlying the joint probability distribution over random fields are not provided and a Gaussian dependence structure is assumed without proper validation in practice. This study, therefore, tests the fitness of several non-Gaussian dependence structures in addition to the common use of the Gaussian dependence structure. A soil profile of cone penetration test (CPT) data is collected, and a pair-wise likelihood estimate approach is adopted to identify the best fit dependence structure. The results reveal that both  q c   and  f s   of the CPT profile exhibit the same non-Gaussian dependence characteristics, which challenges the Gaussian assumption. Generation of random fields with a non-Gaussian dependence structure is then proposed. Two slope examples where the spatial fluctuation of shear strength is respectively modeled using stationary and non-stationary random fields are used to investigate the deviation in failure probability due to different dependence structures. The effect of the dependence structure is non-trivial except when the random field is highly ragged or highly smooth. The results highlight the importance of copulas for dependence characterization in random fields.",
        "keywords": "",
        "authors": [
            {
                "name": "Fan Wang",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Kowloon, Hong Kong"
            },
            {
                "name": "Fan Wang",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Kowloon, Hong Kong"
            },
            {
                "name": "Fan Wang",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Kowloon, Hong Kong"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Kowloon, Hong Kong"
            }
        ],
        "venue": "Structural Safety",
        "year": 2018
    },
    "Cpi5vz3j": {
        "id": "Cpi5vz3j",
        "title": "MODELLING THE STOCHASTIC DEPENDENCE UNDERLYING CONSTRUCTION COST AND DURATION",
        "abstract": "Construction cost and duration are two critical project indicators. It is acknowledged that these two indicators are closely dependent and highly uncertain due to various common factors and limited data for explanatory model calibration. However, the stochastic dependence underlying construction cost and duration is usually ignored and the subsequent probabilistic analysis can be misleading. In response, this study develops a Nataf distribution model of building cost and duration, in which the uncertainties of total cost, unit cost, and duration are respectively quantified by univariate distribution fitting, while their stochastic dependence is inferred by maximum likelihood estimation. This method is applied to the costs and durations of 77 China residential building projects completed between 2011 and 2016. The goodness of fit test illustrates that the data conform well to the developed model. The conditional distributions of cost and duration are then derived and the corresponding conditional expectations and variances are given. The results provide the distribution of building costs for a desired duration and the expected duration given a budget. This, together with the ability to update probabilities when new project information is available, confirms the potential of the proposed model to benefit precontract decision making from a risk perspective.",
        "keywords": "",
        "authors": [
            {
                "name": "Xue Xiao",
                "org": ""
            },
            {
                "name": "Fan Wang",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong"
            },
            {
                "name": "Martin Skitmore",
                "org": "Science and Engineering Faculty, Queensland University of Technology, Brisbane, Australia"
            }
        ],
        "venue": "Journal of Civil Engineering and Management",
        "year": 2018
    },
    "l4xf24WH": {
        "id": "l4xf24WH",
        "title": "Distribution modeling for reliability analysis: Impact of multiple dependences and probability model selection",
        "abstract": "Abstract   Reliability analysis requires modeling of joint probability distribution of uncertain parameters, which can be a challenge since the random variables representing the parameter uncertainties may be correlated. For convenience, a Gaussian data dependence is commonly assumed for correlated random variables. This paper first investigates the effect of multidimensional non-Gaussian data dependences underlying the multivariate probability distribution on reliability results. Using different bivariate copulas in a vine structure, various data dependences can be modeled. The associated copula parameters are identified from available statistical information by moment matching techniques. After the development of the vine copula model for representing the multivariate probability distribution, the reliability involving correlated random variables is evaluated based on the Rosenblatt transformation. The impact of data dependence is significant because a large deviation in failure probability is observed, which emphasizes the need for accurate dependence characterization. A practical method for dependence modeling based on limited data is thus provided. The result demonstrates that the non-Gaussian data dependences can be real in practice, and the reliability can be biased if the Gaussian dependence is used inappropriately. Moreover, the effect of conditioning order on reliability should not be overlooked except that the vine structure contains only one type of copula.",
        "keywords": "",
        "authors": [
            {
                "name": "Fan Wang",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Kowloon, Hong Kong"
            },
            {
                "name": "Fan Wang",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Kowloon, Hong Kong"
            },
            {
                "name": "Fan Wang",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Kowloon, Hong Kong"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Kowloon, Hong Kong"
            }
        ],
        "venue": "Applied Mathematical Modelling",
        "year": 2018
    },
    "mBRQi0dO": {
        "id": "mBRQi0dO",
        "title": "Response\u2013Surface\u2013Based Embankment Reliability under Incomplete Probability Information",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Fan Wang",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Qi-Ling Zhang",
                "org": ""
            }
        ],
        "venue": "International Journal of Geomechanics",
        "year": 2017
    },
    "Ko3lIfN5": {
        "id": "Ko3lIfN5",
        "title": "On the need for dependence characterization in random fields: Findings from cone penetration test (CPT) data",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Fan Wang",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Kowloon, Hong Kong."
            },
            {
                "name": "Fan Wang",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Kowloon, Hong Kong."
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Kowloon, Hong Kong."
            }
        ],
        "venue": "Canadian Geotechnical Journal",
        "year": 2019
    },
    "fNzMMMqZ": {
        "id": "fNzMMMqZ",
        "title": "A practical non-parametric copula algorithm for system reliability with correlations",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Fan Wang",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            }
        ],
        "venue": "Applied Mathematical Modelling",
        "year": 2019
    },
    "3K8vXUDr": {
        "id": "3K8vXUDr",
        "title": "Knowledge representation using non-parametric Bayesian networks for tunneling risk analysis",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Fan Wang",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Chao Dong",
                "org": ""
            },
            {
                "name": "Lieyun Ding",
                "org": ""
            }
        ],
        "venue": "Reliability Engineering & System Safety",
        "year": 2019
    },
    "b8BVjcPq": {
        "id": "b8BVjcPq",
        "title": "Optimal single-machine batch scheduling for the manufacture, transportation and JIT assembly of precast construction with changeover costs within due dates",
        "abstract": "Abstract   The manufacture, transportation and on-site assembly sectors of precast construction projects are often considered separately and managed by rule of thumb, causing an inefficient use of resources and postponed delivery. This study views these sectors as a whole from the perspective of a single machine batch-scheduling problem. A dynamic programming algorithm, which aims to search for solutions that entail maximum production efficiency, was developed accordingly with the constraints of changeover costs and production deadlines. We tested the method\u2019s ability by processing as many products as possible simultaneously using real data collected from a precast factory in a simulation and compared the effect with a previous study. We found that our method possesses great potential to improve the efficiency of precast production.",
        "keywords": "",
        "authors": [
            {
                "name": "Liulin Kong",
                "org": "School of Civil Engineering & Mechanics, Huazhong University of Science & Technology, China"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong"
            },
            {
                "name": "Hanbin Luo",
                "org": "School of Civil Engineering & Mechanics, Huazhong University of Science & Technology, China"
            },
            {
                "name": "Lieyun Ding",
                "org": "School of Civil Engineering & Mechanics, Huazhong University of Science & Technology, China"
            },
            {
                "name": "Xiaochun Luo",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong"
            },
            {
                "name": "Martin Skitmore",
                "org": "School of Civil Engineering and Built Environment, Queensland University of Technology (QUT), Australia"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2017
    },
    "nKPTmXtb": {
        "id": "nKPTmXtb",
        "title": "Detecting non-hardhat-use by a deep learning method from far-field surveillance videos",
        "abstract": "Abstract   Hardhats are an important safety measure used to protect construction workers from accidents. However, accidents caused in ignorance of wearing hardhats still occur. In order to strengthen the supervision of construction workers to avoid accidents, automatic non-hardhat-use (NHU) detection technology can play an important role. Existing automatic methods of detecting hardhat avoidance are commonly limited to the detection of objects in near-field surveillance videos. This paper proposes the use of a high precision, high speed and widely applicable Faster R-CNN method to detect construction workersu0027 NHU. To evaluate the performance of Faster R-CNN, more than 100,000 construction worker image frames were randomly selected from the far-field surveillance videos of 25 different construction sites over a period of more than a year. The research analyzed various visual conditions of the construction sites and classified image frames according to their visual conditions. The image frames were input into Faster R-CNN according to different visual categories. The experimental results demonstrate that the high precision, high recall and fast speed of the method can effectively detect construction workersu0027 NHU in different construction site conditions, and can facilitate improved safety inspection and supervision.",
        "keywords": "",
        "authors": [
            {
                "name": "Qi Fang",
                "org": "School of Civil Engineering &Mechanics, Huazhong University of Science & Technology, Wuhan, China"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong"
            },
            {
                "name": "Xiaochun Luo",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong"
            },
            {
                "name": "Lieyun Ding",
                "org": "School of Civil Engineering &Mechanics, Huazhong University of Science & Technology, Wuhan, China"
            },
            {
                "name": "Hanbin Luo",
                "org": "School of Civil Engineering &Mechanics, Huazhong University of Science & Technology, Wuhan, China"
            },
            {
                "name": "Timothy M. Rose",
                "org": "School of Civil Engineering and Built Environment, Queensland University of Technology, Australia"
            },
            {
                "name": "Wangpeng An",
                "org": "Department of Computing, The Hong Kong Polytechnic University, Hong Kong"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2018
    },
    "M126qAhZ": {
        "id": "M126qAhZ",
        "title": "Proactive struck-by risk detection with movement patterns and randomness",
        "abstract": "Abstract   This study proposes a proactive struck-by risk detection method for workers proximal to the laydown area. This approach regards the laydown area as a radiation source, and proactive struck-by risk detection is formulated as a location-based estimate of radiation quantity received by the worker. The position probability grid is adopted to track the worker and model their movement. The movement pattern model, which is learned from the trajectory records of the workers in the same trade, reflects the movement preferences of different trades, and the randomness model represents the randomness of worker movement. The workeru0027s next location can be predicted by using the tracked location and movement model, and the struck-by risk can then be estimated. The methodu0027s potential for integration into currently available proximity warning systems is also demonstrated.",
        "keywords": "",
        "authors": [
            {
                "name": "Chao Dong",
                "org": "School of Civil Engineering & Mechanics, Huazhong University of Science & Technology, Wuhan, China"
            },
            {
                "name": "Chao Dong",
                "org": "School of Civil Engineering & Mechanics, Huazhong University of Science & Technology, Wuhan, China"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong"
            },
            {
                "name": "Xiaochun Luo",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong"
            },
            {
                "name": "Lieyun Ding",
                "org": "School of Civil Engineering & Mechanics, Huazhong University of Science & Technology, Wuhan, China"
            },
            {
                "name": "Joanna Izabela Siebert",
                "org": "Department of Computing, The Hong Kong Polytechnic University, Hong Kong"
            },
            {
                "name": "Hanbin Luo",
                "org": "School of Civil Engineering & Mechanics, Huazhong University of Science & Technology, Wuhan, China"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2018
    },
    "CUbTTLzf": {
        "id": "CUbTTLzf",
        "title": "Knowledge dynamics-integrated map as a blueprint for system development: Applications to safety risk management in Wuhan metro project",
        "abstract": "Abstract   Safety has always been a persistent problem in the construction industry, particularly for tunnel construction projects due to the inherent uncertainty in geotechnical conditions and the complexity of the tunnel construction process. Literatures and practices highlight the importance of safety knowledge to the construction safety. However, safety knowledge is not always provided in a convenient and timely manner. This paper develops a Knowledge-dynamics Integrated Map (KIM) to visualize safety knowledge flow in tunnel construction safety risk management. The KIM highlights the what, the who, and the why of knowledge flow by portraying its dynamics associated to the working processes. With the use of KIM, the safety knowledge flow barriers are identified so that knowledge flow facilitators can be designed. The KIM has been applied in Wuhan metro project as a blueprint for systematically developing effective safety knowledge management systems.",
        "keywords": "",
        "authors": [
            {
                "name": "Chao Dong",
                "org": "School of Civil Engineering & Mechanics, Huazhong University of Science & Technology, Wuhan, China"
            },
            {
                "name": "Chao Dong",
                "org": "School of Civil Engineering & Mechanics, Huazhong University of Science & Technology, Wuhan, China"
            },
            {
                "name": "Fan Wang",
                "org": "School of Civil Engineering & Mechanics, Huazhong University of Science & Technology, Wuhan, China"
            },
            {
                "name": "Fan Wang",
                "org": "School of Civil Engineering & Mechanics, Huazhong University of Science & Technology, Wuhan, China"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong"
            },
            {
                "name": "Lieyun Ding",
                "org": "School of Civil Engineering & Mechanics, Huazhong University of Science & Technology, Wuhan, China"
            },
            {
                "name": "Hanbin Luo",
                "org": "School of Civil Engineering & Mechanics, Huazhong University of Science & Technology, Wuhan, China"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2018
    },
    "mRxHJQbv": {
        "id": "mRxHJQbv",
        "title": "Computer vision aided inspection on falling prevention measures for steeplejacks in an aerial environment",
        "abstract": "Abstract   Falling from height accidents are a major cause of fatalities on construction sites. Despite a lot of research conducted on the enhancement of safety training and removal of hazardous areas, falling accidents remain a major threat for steeplejacks. According to NOISH FACE reports, 75.1% of the fall from height decedents didnu0027t use the Personal Fall Arrest Systems (PFAS), which shows insufficient supervision of the use of Personal Protective Equipment (PPE) by steeplejacks. Few scholars consider PFAS an important measure to prevent falls and the existing studies on PPE inspections showed that they were unsuitable for the scenarios faced by steeplejacks. This paper proposes an automated inspection method to check PPEsu0027 usage by steeplejacks who are ready for aerial work beside exterior walls. An aerial operation scenario understanding method is proposed, which makes the inspection a preventative control measure and highly robust to noise. A deep-learning based occlusion mitigation method for PPE checking is introduced. We tested the performance of our method under various conditions and the experimental results demonstrate the reliability and robustness of our method to inspect falling prevention measures for steeplejacks and can help facilitate safety supervision.",
        "keywords": "",
        "authors": [
            {
                "name": "Qi Fang",
                "org": "School of Civil Engineering &Mechanics, Huazhong University of Science & Technology, Wuhan, China"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong"
            },
            {
                "name": "Xiaochun Luo",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong"
            },
            {
                "name": "Lieyun Ding",
                "org": "School of Civil Engineering &Mechanics, Huazhong University of Science & Technology, Wuhan, China"
            },
            {
                "name": "Hanbin Luo",
                "org": "School of Civil Engineering &Mechanics, Huazhong University of Science & Technology, Wuhan, China"
            },
            {
                "name": "Chengqian Li",
                "org": "School of Civil Engineering &Mechanics, Huazhong University of Science & Technology, Wuhan, China"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2018
    },
    "FsUZDc6B": {
        "id": "FsUZDc6B",
        "title": "A scientometric analysis and critical review of construction related ontology research",
        "abstract": "Abstract   There is a wide range of literature on adopting ontology to solve construction problems, but no review of existing studies has systematically analyzed and visualized the trends in ontology research. This study reviews ontology research mainly published in the Scopus database from 2007 to 2017 with the combination of scientometric analysis and critical review. Scientometric analysis (e.g. co-author, co-word, co-citation, and clusters) objectively visualized the research status quo while a critical review was used to identify the research themes and challenges of ontology research in the construction industry. The results identified a large network of co-authors in this field to understand collaboration relationships. Over half the papers (53%) were published by the following three countries: the United States, the United Kingdom, and Canada. The top co-occurring keywords were \u201cproject management\u201d at which ontology facilitates knowledge management and information retrieval. When the time factor was taken into consideration, keywords naturally evolved from \u201cproject management\u201d, and \u201cknowledge management\u201d to \u201cbuilding information modeling\u201d, and \u201ccompliance control\u201d with the successful adoption of information techniques in the construction industry. Four research themes were identified with the combination of cluster analysis and critical review: \u201cDomain ontology\u201d, \u201cIndustry foundation classes\u201d, \u201cAutomated compliance checking\u201d, and \u201cBuilding information modeling\u201d. This review provides an in-depth understanding of existing ontology research and indicates the emerging trends in this research domain.",
        "keywords": "",
        "authors": [
            {
                "name": "Botao Zhong",
                "org": "Department of Construction Management, School of Civil Engineering & Mechanics, Huazhong University of Science & Technology, Wuhan, Hubei, China"
            },
            {
                "name": "Haitao Wu",
                "org": "Department of Construction Management, School of Civil Engineering & Mechanics, Huazhong University of Science & Technology, Wuhan, Hubei, China"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Kowloon, Hong Kong"
            },
            {
                "name": "Samad Sepasgozar",
                "org": "Faculty of Built Environment, University of New South Wales Sydney, Australia"
            },
            {
                "name": "Hanbin Luo",
                "org": "Department of Construction Management, School of Civil Engineering & Mechanics, Huazhong University of Science & Technology, Wuhan, Hubei, China"
            },
            {
                "name": "Ling He",
                "org": "Department of Construction Management, School of Civil Engineering & Mechanics, Huazhong University of Science & Technology, Wuhan, Hubei, China"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2019
    },
    "uEvY1EDX": {
        "id": "uEvY1EDX",
        "title": "Ontology for safety risk identification in metro construction",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Xuejiao Xing",
                "org": ""
            },
            {
                "name": "Botao Zhong",
                "org": ""
            },
            {
                "name": "Hanbin Luo",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Haitao Wu",
                "org": ""
            }
        ],
        "venue": "Computers in Industry",
        "year": 2019
    },
    "TzbDJkjM": {
        "id": "TzbDJkjM",
        "title": "A multicomponent and neurophysiological intervention for the emotional and mental states of high-altitude construction workers",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Xuejiao Xing",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Jue Li",
                "org": ""
            },
            {
                "name": "Botao Zhong",
                "org": ""
            },
            {
                "name": "Hanbin Luo",
                "org": ""
            },
            {
                "name": "Martin Skitmore",
                "org": ""
            }
        ],
        "venue": "Automation in Construction",
        "year": 2019
    },
    "gcO2mIA1": {
        "id": "gcO2mIA1",
        "title": "The availability of wearable-device-based physical data for the measurement of construction workers' psychological status on site: From the perspective of safety management",
        "abstract": "Abstract   Workersu0027 unsafe behaviors have been recognized as one of the main causes to construction accidents, while the existing research shows that workersu0027 psychological status on site has a direct influence on their behaviors. Thus monitoring workersu0027 psychological status may benefit the reduction of unsafe behaviors on site, thus preventing accident from occurring. However, due to the lack of appropriate methods to collect jobsite workersu0027 psychological data, it is difficult for the existing research to reveal the relationship between psychological status and unsafe behavior. This research proposes an efficient wearable technology-based method to collect jobsite workersu0027 psychological data to support such an analysis. Wearable-device-based physical data collection has been regarded as a promising approach to study humanu0027s psychological status in the field of psychology, and applied to pedagogy and clinical psychology, but seldom in the construction industry. The purpose of this research is to study the availability of the approach in construction safety management. To do this, an on-site experiment was conducted to collect workersu0027 physical data via using wearable devices, as well as psychological data through the use of PANAS (Positive and Negative Affect Schedule) and DRM (Day Reconstruction Method). Based on the data, the correlations between workersu0027 psychological status and physical data are analyzed. The results show that jobsite workersu0027 physical data is available for the measurement of workersu0027 psychological status. This research will contribute to the research on jobsite workersu0027 psychology in the context of real construction sites, as well as the identification of the mental causes of workersu0027 unsafe behaviors on site, thus improving the performance of construction safety management.",
        "keywords": "",
        "authors": [
            {
                "name": "Hongling Guo",
                "org": "Department of Construction Management, Tsinghua University, Beijing, China"
            },
            {
                "name": "Yantao Yu",
                "org": "Department of Construction Management, Tsinghua University, Beijing, China"
            },
            {
                "name": "Tian Xiang",
                "org": "Department of Construction Management, Tsinghua University, Beijing, China"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong, China"
            },
            {
                "name": "Dan Zhang",
                "org": ""
            }
        ],
        "venue": "Automation in Construction",
        "year": 2017
    },
    "ptIX4cxf": {
        "id": "ptIX4cxf",
        "title": "An experimental study of real-time identification of construction workers' unsafe behaviors",
        "abstract": "Abstract   Construction workersu0027 unsafe behavior is one of the main reasons leading to construction accidents. However, the existing management approach to unsafe behaviors, e.g. Behavior-Based Safety (BBS), relies primarily on manual observation and recording, which not only consumes lots of time and cost but impossibly cover a whole construction site or all workers. To solve this problem and improve safety performance, an image-skeleton-based parameterized method has been proposed in a previous research to real-time identifying construction workersu0027 unsafe behaviors. A theoretical framework has been developed with a preliminary test, but still lacking a comprehensive experiment to verify its validity, particularly in the recognition of the types of unsafe behaviors. This will have a serious impact on the extensive application of the method in real construction sites. Based on the method, this research designs and carries out a series of experiments involving three types of unsafe behaviors to examine its feasibility and accuracy, and determines the value ranges of relevant key parameters. The results of the experiment demonstrate the feasibility and efficiency of the method, being able to identify and distinguish unsafe behaviors in real time, as well as its limitations. This research not only benefits the extensive application of the method in construction safety management, but improves the effectiveness and efficiency of the method by identifying relevant future research focuses. Therefore this paper contributes to the practice as well as the body of knowledge of construction safety management.",
        "keywords": "",
        "authors": [
            {
                "name": "Yantao Yu",
                "org": "Department of Construction Management, Tsinghua University, Beijing, China"
            },
            {
                "name": "Hongling Guo",
                "org": "Department of Construction Management, Tsinghua University, Beijing, China"
            },
            {
                "name": "Qinghua Ding",
                "org": "Department of Computer Science and Technology, Tsinghua University, Beijing, China"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong"
            },
            {
                "name": "Martin Skitmore",
                "org": "School of Engineering and Built Environment, Queensland University of Technology (QUT), Australia"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2017
    },
    "TMC23unb": {
        "id": "TMC23unb",
        "title": "Wearable insole pressure system for automated detection and classification of awkward working postures in construction workers",
        "abstract": "Abstract   Awkward working postures are the main risk factor for work-related musculoskeletal disorders (WMSDs) causing non-fatal occupational injuries among construction workers. However, it remains a challenge to use existing risk assessment methods for detecting and classifying awkward working postures because these methods are either intrusive or rely on subjective judgment. Therefore, this study developed a novel and non-invasive method to automatically detect and classify awkward working postures based on foot plantar pressure distribution data measured by a wearable insole pressure system. Ten asymptomatic participants performed five different types of awkward working postures (i.e., overhead working, squatting, stooping, semi-squatting, and one-legged kneeling) in a laboratory setting. Four supervised machine learning classifiers (i.e., artificial neural network (ANN), decision tree (DT),  K -nearest neighbor (KNN), and support vector machine (SVM)) were used for classification performance using a 0.32\u202fs window size. Cross-validation results showed that the SVM classifier (i.e., the best classifier) obtained a classification performance with an accuracy of 99.70% and a sensitivity of each awkward working posture was above 99.00% at 0.32\u202fs window size. The findings substantiated that it is feasible to use a wearable insole pressure system to identify risk factors for developing WMSDs, and could help safety managers to minimize workersu0027 exposure to awkward working postures.",
        "keywords": "",
        "authors": [
            {
                "name": "Maxwell Fordjour Antwi-Afari",
                "org": "Department of Building and Real Estate, Faculty of Construction and Environment, Hong Kong Polytechnic University, Room No. ZN1002, Hung Hom, Kowloon, Hong Kong Special Administrative Region"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, Faculty of Construction and Environment, Hong Kong Polytechnic University, Room No. ZS734, Hung Hom, Kowloon, Hong Kong Special Administrative Region"
            },
            {
                "name": "Yantao Yu",
                "org": "Department of Building and Real Estate, Faculty of Construction and Environment, Hong Kong Polytechnic University, Room No. ZN1002, Hung Hom, Kowloon, Hong Kong Special Administrative Region"
            },
            {
                "name": "Liulin Kong",
                "org": "Department of Building and Real Estate, Faculty of Construction and Environment, Hong Kong Polytechnic University, Room No. ZN1002, Hung Hom, Kowloon, Hong Kong Special Administrative Region"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2018
    },
    "Br0UETi3": {
        "id": "Br0UETi3",
        "title": "An automatic and non-invasive physical fatigue assessment method for construction workers",
        "abstract": "Abstract   The construction industry around the globe has unsatisfactory occupational health and safety records. One of the major reasons is attributed to high physical demands and hostile working environments. Construction work always requires workers to work for a long duration without sufficient breaks to recover from overexertion and to work under harsh climatic conditions and/or in confined workspaces. Such circumstances can increase the risk of physical fatigue. Traditionally, fatigue monitoring in the construction domain relies on self-reporting or subjective questionnaires. These methods require the manual collection of responses and are impractical for continuous fatigue monitoring. Some researchers have used on-body sensors for fatigue monitoring (such as heart rate monitors and surface electromyography (sEMG) sensors). Although these devices appear to be promising, they are intrusive, requiring sensors to be attached to the workeru0027s body. Such on-body sensors are uncomfortable to wear and could easily cause irritation. Considering the limitations of these methodologies, the current research proposes a novel non-intrusive method to monitor the whole-body physical fatigue with computer vision for construction workers. A computer vision-based 3D motion capture algorithm was developed to model the motion of various body parts using an RGB camera. A fatigue assessment model was developed using the 3D model data from the developed motion capture algorithm and biomechanical analysis. The experiment showed that the proposed physical fatigue assessment method could provide joint-level physical fatigue assessments automatically. Then, a series of experiments demonstrated the potential of the method in assessing the physical fatigue level of different construction task conditions such as site layout and the work-rest schedules.",
        "keywords": "",
        "authors": [
            {
                "name": "Yantao Yu",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Xincong Yang",
                "org": ""
            },
            {
                "name": "Liulin Kong",
                "org": ""
            },
            {
                "name": "Xiaochun Luo",
                "org": ""
            },
            {
                "name": "Arnold Y.L. Wong",
                "org": ""
            }
        ],
        "venue": "Automation in Construction",
        "year": 2019
    },
    "UZ3MnveM": {
        "id": "UZ3MnveM",
        "title": "Critical success factors for implementing building information modelling (BIM): A longitudinal review",
        "abstract": "Abstract   Although building information modelling (BIM) is ubiquitous within the construction industry, a review analysis on critical success factors (CSFs) used to measure successful BIM implementation is not well established. This research conducts a comprehensive review and interpretivist study of published studies on CSFs for BIM implementation during the period 2005 to 2015. Analysis reveals that some countries (e.g. USA, UK and South Korea) have developed clear CSFs for measuring successful BIM implementation, although each country implements a different sets of CSFs, some universal CSFs are shared between these countries, namely:  collaboration in design, engineering, and construction stakeholders; earlier and accurate 3D visualisation of design; coordination and planning of construction works; enhancing exchange of information and knowledge management; and improved site layout planning and site safety . These common factors provide a core basis for establishing a standard evaluation model for measuring the success of BIM implementation and serve to identify areas for further improvement. A checklist of CSFs for BIM implementation is developed, and could render new insight for researchers and practitioners to conduct further empirical studies.",
        "keywords": "",
        "authors": [
            {
                "name": "Maxwell Fordjour Antwi-Afari",
                "org": "Department of Building and Real Estate, Hong Kong Polytechnic University, Room No. ZN1002, Hung Hom, Kowloon, Hong Kong Special Administrative Region"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, Hong Kong Polytechnic University, Room No. ZS734, Hung Hom, Kowloon, Hong Kong Special Administrative Region"
            },
            {
                "name": "Erika Parn",
                "org": "Faculty of Computing, Engineering and the Built Environment (CEBE), Birmingham City University, UK"
            },
            {
                "name": "David J. Edwards",
                "org": "Faculty of Computing, Engineering and the Built Environment (CEBE), Birmingham City University, UK"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2018
    },
    "hyDYl0Pr": {
        "id": "hyDYl0Pr",
        "title": "Automated detection and classification of construction workers' loss of balance events using wearable insole pressure sensors",
        "abstract": "Abstract   Fall on the same level is the leading cause of non-fatal injuries in construction workers; however, identifying loss of balance events associated with specific unsafe surface conditions in a timely manner remain challenging. The objective of the current study was to develop a novel method to detect and classify loss of balance events that could lead to falls on the same level by using foot plantar pressure distributions data captured from wearable insole pressure sensors. Ten healthy volunteers participated in experimental trials, simulating four major loss of balance events (e.g., slip, trip, unexpected step-down, and twisted ankle) to collect foot plantar pressure distributions data. Supervised machine learning algorithms were used to learn the unique foot plantar pressure patterns, and then to automatically detect loss of balance events. We compared classification performance by varying window sizes, feature groups and types of classifiers, and the best classification accuracy (97.1%) was achieved when using the Random Forest classifier with all feature groups and a window size of 0.32\u202fs. This study is important to researchers and site managers because it uses foot plantar pressure distribution data to objectively distinguish various potential loss of balance events associated with specific unsafe surface conditions. The proposed approach can allow practitioners to proactively conduct automated fall risk monitoring to minimize the risk of falls on the same level on sites.",
        "keywords": "",
        "authors": [
            {
                "name": "Maxwell Fordjour Antwi-Afari",
                "org": "Dept. of Building and Real Estate, Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong Special Administrative Region"
            },
            {
                "name": "Heng Li",
                "org": "Dept. of Building and Real Estate, Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong Special Administrative Region"
            },
            {
                "name": "JoonOh Seo",
                "org": "Dept. of Building and Real Estate, Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong Special Administrative Region"
            },
            {
                "name": "Arnold Yu Lok Wong",
                "org": ""
            }
        ],
        "venue": "Automation in Construction",
        "year": 2018
    },
    "7PdbC6o1": {
        "id": "7PdbC6o1",
        "title": "Biomechanical analysis of risk factors for work-related musculoskeletal disorders during repetitive lifting task in construction workers",
        "abstract": "Work-related musculoskeletal disorders (WMSDs) represent major health issues for construction workers yet risk factors associated with repetitive lifting tasks remain unexplored. This study evaluates the effects of lifting weights and postures on spinal biomechanics (i.e. muscle activity and muscle fatigue) during a simulated repetitive lifting task undertaken within a strictly controlled laboratory experimental environment. Twenty healthy male participants performed simulated repetitive lifting tasks with three different lifting weights using either a stoop (n = 10) or a squat (n = 10) lifting posture until subjective fatigue (a point in time at which the participant cannot continue lifting further). Spinal biomechanics during repetitive lifting tasks were measured by surface electromyography (sEMG). Results revealed that (1) increased lifting weights significantly increased sEMG activity and muscle fatigue of the biceps brachii (BB), brachioradialis (BR), lumbar erector spinae (LES), and medial gastrocnemius (MG) muscles but not the rectus femoris (RF) muscle; (2) sEMG activity and muscle fatigue rate of the LES muscle were higher than all other muscles; (3) a significant difference of sEMG activity of the RF and MG muscles was observed between lifting postures, however no significant difference of muscle fatigue was apparent (p u003e 0.05). These findings suggest that risk factors such as lifting weights, repetitions and lifting postures may alleviate the risk of developing WMSDs. However, future research is required to investigate the effectiveness of using ergonomic interventions (such as using team lifting and adjustable lift equipment) in reducing WMSDs risks in construction workers. This work represents the first laboratory-based simulated testing conducted to investigate work-related musculoskeletal disorders (WMSDs) primarily caused by repetitive lifting tasks and manual handling. Cumulatively, the results and ensuing discussion offer insight into how these risks can be measured and mitigated.",
        "keywords": "",
        "authors": [
            {
                "name": "Maxwell Fordjour Antwi-Afari",
                "org": "Dept. of Building and Real Estate, Hong Kong Polytechnic Univ., Room No. ZN1002, Hung Hom, Kowloon, Hong Kong Special Administrative Region"
            },
            {
                "name": "Heng Li",
                "org": "Dept. of Building and Real Estate, Hong Kong Polytechnic Univ., Room No. ZS734, Hung Hom, Kowloon, Hong Kong Special Administrative Region"
            },
            {
                "name": "David J. Edwards",
                "org": "Faculty of Computing, Engineering and the Built Environment (CEBE), Birmingham City University, UK"
            },
            {
                "name": "Erika Parn",
                "org": "Faculty of Computing, Engineering and the Built Environment (CEBE), Birmingham City University, UK"
            },
            {
                "name": "JoonOh Seo",
                "org": "Dept. of Building and Real Estate, Hong Kong Polytechnic Univ., Room No. ZN737, Hung Hom, Kowloon, Hong Kong Special Administrative Region"
            },
            {
                "name": "Arnold Yu Lok Wong",
                "org": ""
            }
        ],
        "venue": "Automation in Construction",
        "year": 2017
    },
    "jCzuyGWl": {
        "id": "jCzuyGWl",
        "title": "Development of ergonomic posture recognition technique based on 2D ordinary camera for construction hazard prevention through view-invariant features in 2D skeleton motion.",
        "abstract": "\nErgonomic posture recognition is a novel solution to prevent hazard in construction.We use ordinary RGB camera to improve non-intrusiveness and applicability in EPR.We developed EPR classifiers based on 2D ordinary camera for hazard prevention.Our novel solution is through view-invariant features in 2D skeleton motion.Our solution demonstrated robust accuracy for on-site postural ergonomic assessment. Outdoor tasks operated by construction workers are physically demanding, requiring awkward postures leading to pain, injury, accident, or permanent disability. Ergonomic posture recognition (EPR) technique could be a novel solution for ergonomic hazard monitoring and assessment, yet non-intrusiveness and applicability in complex outdoor environment are always critical considerations for device selection in construction site. Thus, we choose RGB camera to capture skeleton motions, which is non-intrusive for workers compared with wearable sensors. It is also stable and widely used in an outdoor construction site considering various light conditions and complex working areas. This study aims to develop an ergonomic posture recognition technique based on 2D ordinary camera for construction hazard prevention through view-invariant features in 2D skeleton motion. Based on captured 2D skeleton motion samples in the test-run, view-invariant features as classifier inputs were extracted to ensure the learned classifier not sensitive to various camera viewpoints and distances to a worker. Three posture classifiers regarding human back, arms, and legs were employed to ensure three postures to be recognized simultaneously in one video frame. The average accuracies of three classifiers in 5-fold cross validation were as high as 95.0%, 96.5%, and 97.6%, respectively, and the overall accuracies tested by three new activities regarding ergonomic assessment scores captured from different camera heights and viewpoints were 89.2%, 88.3%, and 87.6%, respectively. The developed EPR-aided construction accident auto-prevention technique demonstrated robust accuracy to support on-site postural ergonomic assessment for construction workers safety and health assurance.\n",
        "keywords": [
            "2D skeleton",
            " Construction worker",
            " Ergonomics",
            " Person posture recognition",
            " RGB camera",
            " View-invariant"
        ],
        "authors": [
            {
                "name": "Xuzhong Yan",
                "org": "Department of Building and Real Estate, Faculty of Construction and Environment, The Hong Kong Polytechnic University, Hong Kong, China"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, Faculty of Construction and Environment, The Hong Kong Polytechnic University, Hong Kong, China"
            },
            {
                "name": "Chen Wang",
                "org": ""
            },
            {
                "name": "JoonOh Seo",
                "org": "Department of Building and Real Estate, Faculty of Construction and Environment, The Hong Kong Polytechnic University, Hong Kong, China"
            },
            {
                "name": "Hong Zhang",
                "org": "School of Management, Huazhong University of Science and Technology, Wuhan 430074, China"
            },
            {
                "name": "Hongwei Wang",
                "org": "School of Management, Huazhong University of Science and Technology, Wuhan 430074, China"
            }
        ],
        "venue": "Advanced Engineering Informatics",
        "year": 2017
    },
    "JSLwfnFX": {
        "id": "JSLwfnFX",
        "title": "VR-embedded BIM immersive system for QS engineering education.",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Chen Wang",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate; The Hong Kong Polytechnic University; Kowloon Hong Kong"
            },
            {
                "name": "Song Y. Kho",
                "org": "Faculty of Built Environment; University of Malaya; Kuala Lumpur Malaysia"
            }
        ],
        "venue": "Comp. Applic. in Engineering Education",
        "year": 2018
    },
    "5rDVMUbc": {
        "id": "5rDVMUbc",
        "title": "Applied Artificial Bee Colony Optimization Algorithm in Fire Evacuation Routing System.",
        "abstract": "Every minute counts in an event of fire evacuation where evacuees need to make immediate routing decisions in a condition of low visibility, low environmental familiarity, and high anxiety. However, the existing fire evacuation routing models using various algorithm such as ant colony optimization or particle swarm optimization can neither properly interpret the delay caused by congestion during evacuation nor determine the best layout of emergency exit guidance signs; thus bee colony optimization is expected to solve the problem. This study aims to develop a fire evacuation routing model \u201cBee-Fire\u201d using artificial bee colony optimization (BCO) and to test the routing model through a simulation run. Bee-Fire is able to find the optimal fire evacuation routing solutions; thus not only the clearance time but also the total evacuation time can be reduced. Simulation shows that Bee-Fire could save 10.12% clearance time and 15.41% total evacuation time; thus the congestion during the evacuation process could be effectively avoided and thus the evacuation becomes more systematic and efficient.",
        "keywords": "",
        "authors": [
            {
                "name": "Chen Wang",
                "org": ""
            },
            {
                "name": "Lincoln C. Wood",
                "org": "Department of Management, University of Otago, Dunedin 9054, New Zealand"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, Faculty of Construction and Environment, The Hong Kong Polytechnic University, Hung Hom, Hong Kong"
            },
            {
                "name": "Zhenye Aw",
                "org": "Faculty of Built Environment, University of Malaya, 50603 Kuala Lumpur, Malaysia"
            },
            {
                "name": "Abolfazl Keshavarzsaleh",
                "org": "Faculty of Built Environment, University of Malaya, 50603 Kuala Lumpur, Malaysia"
            }
        ],
        "venue": "J. Applied Mathematics",
        "year": 2018
    },
    "jrJHDz3E": {
        "id": "jrJHDz3E",
        "title": "Topographical survey engineering education retrofitted by computer-aided 3D-printing.",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Chen Wang",
                "org": ""
            },
            {
                "name": "Jeffrey B. H. Yap",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Jiayun Chua",
                "org": ""
            },
            {
                "name": "Asrul S. Abdul-Razak",
                "org": ""
            },
            {
                "name": "Faizul Azli Mohd Rahim",
                "org": ""
            }
        ],
        "venue": "Comp. Applic. in Engineering Education",
        "year": 2018
    },
    "mX9LU0Nt": {
        "id": "mX9LU0Nt",
        "title": "Moss-indoor vertical greenery system design protocol: Using moss as an indoor vertical greenery system in the tropics",
        "abstract": "Indoor vertical greenery systems (iVGSs) are usually linked to drawbacks such as high initial investment and maintenance costs, and possible damage to buildings. Plants may attract insects and mosquitoes, and some release excessive pollen if indoors. Moss gardening might be an alternative solution because bryophytes are environment friendly in conserving water, controlling erosion, filtering hazardous chemicals and rainwater, and sequestering carbon. The aim of this study is to develop a Moss-iVGS design protocol by considering the characteristics of a Moss-iVGS prototype, foliage thickness, and the influence of lighting on moss cultivation in the tropics. A mixed approach combining experiments and a questionnaire survey was adopted. Results show that Moss-iVGS can withstand 45 days of drought without any water supply or regular maintenance. The moss was able to absorb moisture from humid air to maintain its survival. Moss is abundant in nature, easy to maintain, has high aesthetic value, and has numerous...",
        "keywords": "",
        "authors": [
            {
                "name": "Chen Wang",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, Faculty of Construction and Environment, Hong Kong Polytechnic University, Hong Kong, Hong Kong"
            },
            {
                "name": "Sze A. Neoh",
                "org": "Faculty of Built Environment, University of Malaya, Kuala Lumpur, Malaysia"
            }
        ],
        "venue": "Indoor and Built Environment",
        "year": 2018
    },
    "7wJu2eAh": {
        "id": "7wJu2eAh",
        "title": "Topographical survey engineering education retrofitted by computer-aided 3D-printing.",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Chen Wang",
                "org": ""
            },
            {
                "name": "Jeffrey B. H. Yap",
                "org": "Lee Kong Chian Faculty of Engineering and Science; Department of Surveying; Universiti Tunku Abdul Rahman (UTAR); Kajang Selangor Malaysia"
            },
            {
                "name": "Heng Li",
                "org": "Faculty of Construction and Environment; Department of Building and Real Estate, The Hong Kong Polytechnic University; Kowloon Hong Kong"
            },
            {
                "name": "Jiayun Chua",
                "org": "Faculty of Built Environment; University of Malaya; Kuala Lumpur Malaysia"
            },
            {
                "name": "Asrul S. Abdul-Razak",
                "org": "Faculty of Built Environment; University of Malaya; Kuala Lumpur Malaysia"
            },
            {
                "name": "Faizul Azli Mohd Rahim",
                "org": "Faculty of Built Environment; University of Malaya; Kuala Lumpur Malaysia"
            }
        ],
        "venue": "Comp. Applic. in Engineering Education",
        "year": 2018
    },
    "4ZjAK5S0": {
        "id": "4ZjAK5S0",
        "title": "Systemic Approach for Constraint-Free Computer Maintenance Management System in Oil and Gas Engineering",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Chen Wang",
                "org": "Distinguished Professor, Director of Intelligence and Automation in Construction Fujian Province Higher-Educational Engineering Research Centre, College of Civil Engineering, Huaqiao Univ., Xiamen 361021, China."
            },
            {
                "name": "Heng Li",
                "org": "Chair Professor, Dept. of Building and Real Estate, Faculty of Construction and Environment, Hong Kong Polytechnic Univ., Hong Kong."
            },
            {
                "name": "Jeffrey Boon Hui Yap",
                "org": "Assistant Professor, Dept. of Surveying, Lee Kong Chian Faculty of Engineering and Science, Univ. Tunku Abdul Rahman (UTAR), Kajang, Selangor 43000, Malaysia (corresponding author)."
            },
            {
                "name": "Azrul Effendi Khalid",
                "org": "Fellow, College of Civil Engineering, Huaqiao Univ., Xiamen 361021, China."
            }
        ],
        "venue": "Journal of Management in Engineering",
        "year": 2019
    },
    "C9eAeGE0": {
        "id": "C9eAeGE0",
        "title": "Developing Shuffled Frog-Leaping Algorithm (SFLA) Method to Solve Power Load-Constrained TCRTO Problems in Civil Engineering",
        "abstract": "It is extensively acknowledged that excessive on-site electricity power load often causes power failure across a construction site and surrounding residential zones and can result in unforeseen schedule delay, construction quality problems, life inconvenience, and even property loss. However, energy management, such as power load optimization, has long been ignored in construction scheduling. This study aims to develop a modified shuffled frog-leaping algorithm (SFLA) approach in project scheduling to aid decision-makers in identifying the best Pareto solution for time-cost-resource trade-off (TCRTO) problems under the constraint of precedence, resource availability, and on-site peak electricity power load. A mathematical model including three objective functions and five constraints was established followed by the application of the modified SLFA on real-case multiobjective optimization problems in construction scheduling. The performance of SLFA was compared with that of the nondominated sorting genetic algorithm (NSGA II). The results showed that the developed new approach was superior in identifying optimal project planning solutions, which could essentially assist on-site power load-oriented schedule decision-making for construction teams.",
        "keywords": "",
        "authors": [
            {
                "name": "Xingyu Tao",
                "org": "School of Construction Management and Real Estate, Chongqing University, Chongqing 400044, China"
            },
            {
                "name": "Heng Li",
                "org": "Chair Professor of Construction Informatics, Department of Building and Real Estate, Faculty of Construction and Environment, Hong Kong Polytechnic University, Room No. ZS734, Hung Hom, Kowloon, Hong Kong"
            },
            {
                "name": "Chao Mao",
                "org": "Associate Professor, School of Construction Management and Real Estate, Chongqing University, Room No. 504, Chongqing 400044, China"
            },
            {
                "name": "Chen Wang",
                "org": "Professor, College of Civil Engineering, Huaqiao University, 361021 Xiamen, China"
            },
            {
                "name": "Jeffrey Boon Hui Yap",
                "org": "Assistant Professor, Department of Surveying, Lee Kong Chian Faculty of Engineering and Science, Universiti Tunku Abdul Rahman (UTAR), 43000 Kajang, Selangor, Malaysia"
            },
            {
                "name": "Samad Sepasgozar",
                "org": "Senior Lecturer, Faculty of Built Environment, University of New South Wales Sydney, Kensington, Australia"
            },
            {
                "name": "Sara Shirowzhan",
                "org": "Research Fellow, Faculty of Built Environment, University of New South Wales Sydney, Kensington, Australia"
            },
            {
                "name": "Timothy Rose",
                "org": "Senior Lecturer, Faculty of Science and Engineering, Queensland University of Technology, Brisbane, Australia"
            }
        ],
        "venue": "Advances in Civil Engineering",
        "year": 2019
    },
    "zszavvJh": {
        "id": "zszavvJh",
        "title": "Modeling resource management in the building design process by information constraint Petri nets",
        "abstract": "",
        "keywords": [
            "petri nets",
            "resource management",
            "simulation",
            "building design"
        ],
        "authors": [
            {
                "name": "feifei cheng",
                "org": ""
            },
            {
                "name": "heng li",
                "org": ""
            },
            {
                "name": "y w wang",
                "org": ""
            },
            {
                "name": "martin skitmore",
                "org": ""
            },
            {
                "name": "p j forsythe",
                "org": ""
            }
        ],
        "venue": "Automation in Construction",
        "year": 2013
    },
    "Mp2yD8hu": {
        "id": "Mp2yD8hu",
        "title": "Chirp-spread-spectrum-based real time location system for construction safety management: A case study",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "heng li",
                "org": ""
            },
            {
                "name": "greg chan",
                "org": ""
            },
            {
                "name": "ting huang",
                "org": ""
            },
            {
                "name": "martin skitmore",
                "org": ""
            },
            {
                "name": "terry y e tao",
                "org": ""
            },
            {
                "name": "eric luo",
                "org": ""
            },
            {
                "name": "jacky chung",
                "org": ""
            },
            {
                "name": "x s chan",
                "org": ""
            },
            {
                "name": "y f li",
                "org": ""
            }
        ],
        "venue": "Automation in Construction",
        "year": 2015
    },
    "HjAcA5gb": {
        "id": "HjAcA5gb",
        "title": "Proactive training system for safe and efficient precast installation",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "heng li",
                "org": ""
            },
            {
                "name": "miaojia lu",
                "org": ""
            },
            {
                "name": "greg chan",
                "org": ""
            },
            {
                "name": "martin skitmore",
                "org": ""
            }
        ],
        "venue": "Automation in Construction",
        "year": 2015
    },
    "7ZgQAA88": {
        "id": "7ZgQAA88",
        "title": "Location-based measurement and visualization for interdependence network on construction sites.",
        "abstract": "\nAppropriately assigning workers to tasks is vitally important in project management. To do this, project managers need to objectively and effectively measure and visualize the spatiotemporal orders of real construction process as well as coordination structure of the workforce. However, currently there is no method/tool available to project managers to represent spatiotemporal orders of construction processes. To address this issue, this paper presents a novel approach to measuring the real spatiotemporal order of onsite tasks as well as the task interdependence by an interdependence network. This approach extracts the distance of workspace distributions as a key interdependence indicator from historical location tracks across different construction stages according to the area-restricted nature of construction activities. It then integrates generated interdependence into a network over time, to imply the cooperation patterns in stages and a task delivery across stages with a holistic view. To validate the approach, location data were collected from 31 workers working in a high-rise housing construction project for one week to construct the interdependence network of this project, which was used to quantitatively evaluate the performance of construction schedule, assignments and cooperation. Results show that the interdependence network is able to provide insightful information on how workers perform individual tasks onsite and it is also an effective tool to identify and display the interactions among site workers.\n",
        "keywords": [
            "Construction activities",
            " Interdependence network",
            " Location-based service",
            " Quantitative measurement"
        ],
        "authors": [
            {
                "name": "Xincong Yang",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic Univ., Hong Kong"
            },
            {
                "name": "Xiaowei Luo",
                "org": "Department of Architecture and Civil Engineering, City University of Hong Kong, Hong Kong"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic Univ., Hong Kong"
            },
            {
                "name": "Xiaochun Luo",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic Univ., Hong Kong"
            },
            {
                "name": "Hongling Guo",
                "org": "Department of Construction Management, Tsinghua University, Beijing, China"
            }
        ],
        "venue": "Advanced Engineering Informatics",
        "year": 2017
    },
    "JUaAta63": {
        "id": "JUaAta63",
        "title": "Automatic Pixel-Level Crack Detection and Measurement Using Fully Convolutional Network.",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Xincong Yang",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Yantao Yu",
                "org": ""
            },
            {
                "name": "Xiaochun Luo",
                "org": ""
            },
            {
                "name": "Ting Huang",
                "org": ""
            },
            {
                "name": "Xu Yang",
                "org": ""
            }
        ],
        "venue": "Comp.-Aided Civil and Infrastruct. Engineering",
        "year": 2018
    },
    "DAgfVzIM": {
        "id": "DAgfVzIM",
        "title": "Computer-Aided Optimization of Surveillance Cameras Placement on Construction Sites.",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Xincong Yang",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Ting Huang",
                "org": ""
            },
            {
                "name": "Ximei Zhai",
                "org": ""
            },
            {
                "name": "Fenglai Wang",
                "org": ""
            },
            {
                "name": "Chen Wang",
                "org": ""
            }
        ],
        "venue": "Comp.-Aided Civil and Infrastruct. Engineering",
        "year": 2018
    },
    "N7J7fEeF": {
        "id": "N7J7fEeF",
        "title": "Dynamics of Project-Based Collaborative Networks for BIM Implementation: Analysis Based on Stochastic Actor-Oriented Models",
        "abstract": "AbstractIn the project-based construction industry, organizations are coupled with each other largely through project-specific collaborative relationships, and the industry-level networks of these project-based relationships closely relate to how knowledge and innovations diffuse among organizations to reshape traditional design and construction activities. Using the method of stochastic actor-oriented models and longitudinal data on registered building information modeling (BIM)-based construction projects in Shanghai, this study examines how the macro structure of the project-based collaborative network for BIM implementation in the regional construction industry evolves over time and how related micromechanisms collectively underpin the evolution of the network. The results provide evidence that the network becomes increasingly dense over time but persistently exhibits small-world properties and the core-periphery structure with a small number of super-connected star organizations. The results further ...",
        "keywords": "",
        "authors": [
            {
                "name": "Dongping Cao",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Guangbin Wang",
                "org": ""
            },
            {
                "name": "Xiaochun Luo",
                "org": ""
            },
            {
                "name": "Xincong Yang",
                "org": ""
            },
            {
                "name": "Dan Tan",
                "org": ""
            }
        ],
        "venue": "Journal of Management in Engineering",
        "year": 2017
    },
    "twRIKMHq": {
        "id": "twRIKMHq",
        "title": "Hierarchical Bayesian Model of Worker Response to Proximity Warnings of Construction Safety Hazards: Toward Constant Review of Safety Risk Control Measures",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Xiaochun Luo",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Fei Dai",
                "org": ""
            },
            {
                "name": "Dongping Cao",
                "org": ""
            },
            {
                "name": "Xincong Yang",
                "org": ""
            },
            {
                "name": "Hongling Guo",
                "org": ""
            }
        ],
        "venue": "Journal of Construction Engineering and Management-asce",
        "year": 2017
    },
    "cZnZW9uz": {
        "id": "cZnZW9uz",
        "title": "Motion-based analysis for construction workers using biomechanical methods",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Xincong Yang",
                "org": ""
            },
            {
                "name": "Yantao Yu",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Xiaochun Luo",
                "org": ""
            },
            {
                "name": "Fenglai Wang",
                "org": ""
            }
        ],
        "venue": "Frontiers of Engineering Management",
        "year": 2017
    },
    "2WkMwCva": {
        "id": "2WkMwCva",
        "title": "Computer-Aided Optimization of Surveillance Cameras Placement on Construction Sites: Computer-aided optimization of surveillance cameras placement on construction sites",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Xincong Yang",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate the Hong Kong Polytechnic University Hung Hom Kowloon Hong Kong"
            },
            {
                "name": "Ting Huang",
                "org": "Department of Building and Real Estate the Hong Kong Polytechnic University Hung Hom Kowloon Hong Kong"
            },
            {
                "name": "Ximei Zhai",
                "org": "Department of Building and Real Estate the Hong Kong Polytechnic University Hung Hom Kowloon Hong Kong"
            },
            {
                "name": "Fenglai Wang",
                "org": "School of Civil Engineering Harbin Institute of Technology Harbin Heilongjiang Province China"
            },
            {
                "name": "Chen Wang",
                "org": ""
            }
        ],
        "venue": "Computer-aided Civil and Infrastructure Engineering",
        "year": 2018
    },
    "IWafPk8I": {
        "id": "IWafPk8I",
        "title": "Towards efficient and objective work sampling: Recognizing workers' activities in site surveillance videos with two-stream convolutional networks",
        "abstract": "Abstract   Capturing the working states of workers on foot allows managers to precisely quantify and benchmark labor productivity, which in turn enables them to evaluate productivity losses and identify causes. Work sampling is a widely used method for this task, while suffers from low efficiency as only one worker is selected for each observation. Attentional selection asymmetry can also bias its uniform object selection assumption. Existing vision-based methods are primarily oriented towards recognizing single, separated activities involving few workers or equipment. In this paper, we introduce an activity recognition method, which receives surveillance videos as input and produces diverse and continuous activity labels of individual workers in the field of view. Convolutional networks are used to recognize activities, which are encoded in spatial and temporal streams. A new fusion strategy is developed to combine the recognition results of the two streams. The experimental results show that our activity recognition method has achieved an average accuracy of 80.5%, which is comparable with the state-of-the-art of activity recognition in the computer vision community, given the severe camera motion and low resolution of site surveillance videos and the marginal inter-class difference and significant intra-class variation of workersu0027 activities. We also demonstrate that our method can underpin the implementation of efficient and objective work sampling. The training and test datasets of the study are publicly available.",
        "keywords": "",
        "authors": [
            {
                "name": "Xiaochun Luo",
                "org": "Dept. of Building and Real Estate, Hong Kong Polytechnic Univ., Hung Hom, Kowloon, Hong Kong"
            },
            {
                "name": "Heng Li",
                "org": "Dept. of Building and Real Estate, Hong Kong Polytechnic Univ., Hung Hom, Kowloon, Hong Kong"
            },
            {
                "name": "Dongping Cao",
                "org": "Dept. of Construction Management and Real Estate, School of Economics and Management, Tongji Univ., 1239 Siping Rd., Shanghai 200092, China"
            },
            {
                "name": "Yantao Yu",
                "org": "Dept. of Building and Real Estate, Hong Kong Polytechnic Univ., Hung Hom, Kowloon, Hong Kong"
            },
            {
                "name": "Xincong Yang",
                "org": "Dept. of Building and Real Estate, Hong Kong Polytechnic Univ., Hung Hom, Kowloon, Hong Kong"
            },
            {
                "name": "Ting Huang",
                "org": "Dept. of Building and Real Estate, Hong Kong Polytechnic Univ., Hung Hom, Kowloon, Hong Kong"
            }
        ],
        "venue": "Automation in Construction",
        "year": 2018
    },
    "OpEUeDLw": {
        "id": "OpEUeDLw",
        "title": "Automatic Pixel-Level Crack Detection and Measurement Using Fully Convolutional Network: Pixel-level crack detection and measurement using FCN",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Xincong Yang",
                "org": "Department of Building and Real Estate, the Hong Kong Polytechnic University, Hung Hom; Hong Kong and School of Civil Engineering, Harbin Institute of Technology; Harbin Heilongjiang China"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate; the Hong Kong Polytechnic University; Hung Hom Hong Kong"
            },
            {
                "name": "Yantao Yu",
                "org": "Department of Building and Real Estate; the Hong Kong Polytechnic University; Hung Hom Hong Kong"
            },
            {
                "name": "Xiaochun Luo",
                "org": "Department of Building and Real Estate; the Hong Kong Polytechnic University; Hung Hom Hong Kong"
            },
            {
                "name": "Ting Huang",
                "org": "Department of Building and Real Estate; the Hong Kong Polytechnic University; Hung Hom Hong Kong"
            },
            {
                "name": "Xu Yang",
                "org": "School of Civil Engineering; Harbin Institute of Technology; Harbin Heilongjiang China"
            }
        ],
        "venue": "Computer-aided Civil and Infrastructure Engineering",
        "year": 2018
    },
    "57pMR5bE": {
        "id": "57pMR5bE",
        "title": "Capturing and Understanding Workers' Activities in Far-Field Surveillance Videos with Deep Action Recognition and Bayesian Nonparametric Learning.",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Xiaochun Luo",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Xincong Yang",
                "org": ""
            },
            {
                "name": "Yantao Yu",
                "org": ""
            },
            {
                "name": "Dongping Cao",
                "org": ""
            }
        ],
        "venue": "Comp.-Aided Civil and Infrastruct. Engineering",
        "year": 2019
    },
    "Nowavps0": {
        "id": "Nowavps0",
        "title": "Automatic Biomechanical Workload Estimation for Construction Workers by Computer Vision and Smart Insoles",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Yantao Yu",
                "org": "Ph.D. Student, Dept. of Building and Real Estate, Hong Kong Polytechnic Univ., Rm ZN1002, Hung Hom, Kowloon 999077, Hong Kong SAR."
            },
            {
                "name": "Heng Li",
                "org": "Chair Professor, Dept. of Building and Real Estate, Hong Kong Polytechnic Univ., Rm ZS734, Hung Hom, Kowloon 999077, Hong Kong SAR."
            },
            {
                "name": "Waleed Umer",
                "org": "Research Associate, Dept. of Building and Real Estate, Hong Kong Polytechnic Univ., Rm ZN1002, Hung Hom, Kowloon 999077, Hong Kong SAR."
            },
            {
                "name": "Chao Dong",
                "org": "Ph.D. Candidate, School of Civil Engineering and Mechanics, Dept. of Construction Management, Huazhong Univ. of Science and Technology, Luoyu Rd. 1037, Hongshan District, Wuhan 430000, China."
            },
            {
                "name": "Xincong Yang",
                "org": "Ph.D. Candidate, Dept. of Building and Real Estate, Hong Kong Polytechnic Univ., Rm ZN1002, Hung Hom, Kowloon 999077, Hong Kong SAR (corresponding author)."
            },
            {
                "name": "Martin Skitmore",
                "org": "Queensland University of Technology"
            },
            {
                "name": "Arnold Y. L. Wong",
                "org": "Assistant Professor, Dept. of Rehabilitation Sciences, Hong Kong Polytechnic Univ., Room No. ST512, Hung Hom, Kowloon 999077, Hong Kong SAR."
            }
        ],
        "venue": "Journal of Computing in Civil Engineering",
        "year": 2019
    },
    "w2Nrof4j": {
        "id": "w2Nrof4j",
        "title": "Joint-Level Vision-Based Ergonomic Assessment Tool for Construction Workers",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Yantao Yu",
                "org": "Ph.D. Student, Dept. of Building and Real Estate, Hong Kong Polytechnic Univ., Hung Hom, Kowloon 999077, Hong Kong."
            },
            {
                "name": "Xincong Yang",
                "org": "Ph.D. Candidate, Dept. of Building and Real Estate, Hong Kong Polytechnic Univ., Hung Hom, Kowloon 999077, Hong Kong."
            },
            {
                "name": "Heng Li",
                "org": "Chair Professor, Dept. of Building and Real Estate, Hong Kong Polytechnic Univ., Hung Hom, Kowloon 999077, Hong Kong."
            },
            {
                "name": "Xiaochun Luo",
                "org": "Senior Research Fellow, Dept. of Building and Real Estate, Hong Kong Polytechnic Univ., Hung Hom, Kowloon 999077, Hong Kong."
            },
            {
                "name": "Hongling Guo",
                "org": "Associate Professor, Dept. of Construction Management, Tsinghua Univ., Beijing 100000, China (corresponding author)."
            },
            {
                "name": "Qi Fang",
                "org": "Ph.D. Student, School of Civil Engineering and Mechanics, Huazhong Univ. of Science and Technology, Wuhan 430000, China."
            }
        ],
        "venue": "Journal of Construction Engineering and Management-asce",
        "year": 2019
    },
    "vmLt7qF4": {
        "id": "vmLt7qF4",
        "title": "A field experiment of workers\u2019 responses to proximity warnings of static safety hazards on construction sites",
        "abstract": "This paper describes an experimental study of workers\u2019 responses to proximity warnings of static safety hazards on construction sites using a location-based proximity warning system named the  Proactive Construction Management System (PCMS) . A method of evaluating workers\u2019 responses to proximity warnings is proposed. The method consists of six variables: warning time and distance (the time and the minimum distance to a hazard when a worker receives a warning), dangerous time and distance (the time and the minimum distance to the hazard when the worker comes close to the hazard), and response time and distance (the difference between dangerous time and warning time, and the difference between dangerous distance and warning distance). Finally, whether a worker responds to a warning is evaluated against a two-second threshold and a two-meter threshold in terms of response time and distance respectively.The experiment was conducted over 17 workdays with the participation of 72 workers and resulted in 5391 warnings on a real-life construction project in Shanghai, China. The workers\u2019 responses were analyzed with respect to two factors: building trades and a-priori risk levels. The research found that workers responded to proximity warnings actively, but slightly differently across the selected building trades; carpenters had longer response latency in hazardous areas than ironworkers did, and response percentages were high for hazardous areas with high risks. The results also show evidence that PCMS has the potential to improve workers\u2019 safety performance. The limitations of the present study and future research directions are also addressed.",
        "keywords": [
            "construction safety"
        ],
        "authors": [
            {
                "name": "xiaochun luo",
                "org": ""
            },
            {
                "name": "heng li",
                "org": ""
            },
            {
                "name": "ting huang",
                "org": ""
            },
            {
                "name": "timothy m rose",
                "org": ""
            }
        ],
        "venue": "Safety Science",
        "year": 2016
    },
    "06kfrAJF": {
        "id": "06kfrAJF",
        "title": "Stochastic state sequence model to predict construction site safety states through Real-Time Location Systems",
        "abstract": "This paper addresses the challenge to design an effective method for managers to efficiently process hazardous states via recorded historical data by developing a stochastic state sequence model to predict discrete safety states \u2013 represent the hazardous level of a project or individual person over a period of time through a  Real-Time Location System (RTLS)  on construction sites. This involves a mathematical model for state prediction that is suitable for the big-data environment of modern complex construction projects. Firstly, an algorithm is constructed for extracting incidents from pre-analysis of the walk-paths of site workers based on RTLS. The algorithm builds three categories of hazardous region distribution \u2013 certain static, uncertain static and uncertain dynamic \u2013 and employs a frequency and duration filter to remove noise and misreads. Key regions are identified as either \u2018hazardous\u2019, \u2018risky\u2019, \u2018admonitory\u2019 or \u2018safe\u2019 depending on the extent of the hazard zone from the object\u2019s boundary, and state recognition is established by measuring incidents occurring per day and classifies personal and project states into \u2018normal\u2019, \u2018incident\u2019, \u2018near-miss\u2019 and \u2018accident\u2019. A  Discrete-Time Markov Chain (DTMC)  mathematical model, focusing on the interrelationship between states, is developed to predict states on construction sites. Finally, a case study is provided to demonstrate how the system can assist in monitoring discrete states and which indicates it is feasible for the construction industry.",
        "keywords": [
            "construction"
        ],
        "authors": [
            {
                "name": "heng li",
                "org": ""
            },
            {
                "name": "xincong yang",
                "org": ""
            },
            {
                "name": "fenglai wang",
                "org": ""
            },
            {
                "name": "timothy m rose",
                "org": ""
            },
            {
                "name": "greg chan",
                "org": ""
            },
            {
                "name": "shuang dong",
                "org": ""
            }
        ],
        "venue": "Safety Science",
        "year": 2016
    },
    "lMrBbMtc": {
        "id": "lMrBbMtc",
        "title": "Quantifying Hazard Exposure Using Real-Time Location Data of Construction Workforce and Equipment",
        "abstract": "AbstractTraditional risk-assessment methods typically evaluate accident probability, exposure frequency or duration, and consequence severity, respectively, and finally determine a quantitative risk score or a qualitative risk level. The assessment process is prospective and subjective. Changing and complex construction situations impede their practical and efficient application. To assess safety risk with regard to changing site conditions in an objective and efficient way, this study proposes a quantitative model for hazard exposure assessment based on real-time location data of construction workforce and equipment, collected by a location-based proximity warning system. In contrast with traditional risk-assessment methods, the model proposed in this study combines accident probability and hazard exposure duration into a single quantitative concept\u2014hazard exposure amount. This concept takes into account the space factor as well as the time factor of construction activities. For ease of understanding, a ...",
        "keywords": "",
        "authors": [
            {
                "name": "Xiaochun Luo",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Ting Huang",
                "org": ""
            },
            {
                "name": "Martin Skitmore",
                "org": ""
            }
        ],
        "venue": "Journal of Construction Engineering and Management-asce",
        "year": 2016
    },
    "zBDm7uka": {
        "id": "zBDm7uka",
        "title": "Recognizing diverse construction activities in site images via relevance networks of construction-related objects detected by convolutional neural networks",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Xiaochun Luo",
                "org": "Senior Research Fellow, Dept. of Building and Real Estate, Hong Kong Polytechnic Univ., Hung Hom, Kowloon 999077, Hong Kong (corresponding author)."
            },
            {
                "name": "Heng Li",
                "org": "Chair Professor, Dept. of Building and Real Estate, Hong Kong Polytechnic Univ., Hung Hom, Kowloon 999077, Hong Kong."
            },
            {
                "name": "Dongping Cao",
                "org": "Assistant Professor, Dept. of Construction Management and Real Estate, School of Economics and Management, Tongji Univ., 1239 Siping Rd., Shanghai 200092, China."
            },
            {
                "name": "Fei Dai",
                "org": "Assistant Professor, Dept. of Civil and Environmental Engineering, West Virginia Univ., Morgantown, WV 26506-6103."
            },
            {
                "name": "JoonOh Seo",
                "org": "Assistant Professor, Dept. of Building and Real Estate, Hong Kong Polytechnic Univ., Hung Hom, Kowloon 999077, Hong Kong."
            },
            {
                "name": "SangHyun Lee",
                "org": "Associate Professor, Dept. of Civil and Environmental Engineering, Tishman Construction Management Program, Univ. of Michigan, Ann Arbor, MI 48109."
            }
        ],
        "venue": "Journal of Computing in Civil Engineering",
        "year": 2018
    },
    "dvRWNgC2": {
        "id": "dvRWNgC2",
        "title": "Quantifying the physical intensity of construction workers, a mechanical energy approach.",
        "abstract": "Abstract   Construction workers typically undertake highly demanding physical tasks involving various types of stresses from awkward postures, using excessive force, highly repetitive actions, and excessive energy expenditure, which increases the likelihood of unsafe actions, productivity loss, and human errors. Biomechanical models have been developed to estimate joint loadings, which can help avoid strenuous physical exertion, potentially enhancing construction workforce productivity, safety, and well-being. However, the models used are mainly in 2D, or to predict static strength ignored their velocity and acceleration or using marker-based method for dynamic motion data collection. To address this issue, this paper proposes a novel framework for investigating the mechanical energy expenditure (MEE) of workers using a 3D biomechanical model based on computer vision-based techniques. Human 3D Pose Estimation algorithm based on 2D videos is applied to approximate the coordinates of human joints for working postures, and smart insoles are used to collect foot pressures and plantar accelerations, as input data for the biomechanical analyses. The results show a detailed MEE rate for the whole body, at which joints the maximum and minimum values were obtained to avoid excessive physical exertion. The proposed method can approximate the total daily MEE of construction tasks by summing the assumed cost of individual tasks (such as walking, lifting, and stooping), providing suggestions for the design of a daily workload that workers can sustain without developing cumulative fatigue.",
        "keywords": "",
        "authors": [
            {
                "name": "Liulin Kong",
                "org": "Department of Civil Engineering and Mechanics, Huazhong University of Science and Technology, Wuhan, PR China"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong"
            },
            {
                "name": "Yantao Yu",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong"
            },
            {
                "name": "Hanbin Luo",
                "org": "Department of Civil Engineering and Mechanics, Huazhong University of Science and Technology, Wuhan, PR China"
            },
            {
                "name": "Ronald Martin Skitmore",
                "org": ""
            },
            {
                "name": "Maxwell Fordjour Antwi-Afari",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong"
            }
        ],
        "venue": "Advanced Engineering Informatics",
        "year": 2018
    },
    "eLRA9BAZ": {
        "id": "eLRA9BAZ",
        "title": "Sustainable performance of just-in-time (JIT) management in time-dependent batch delivery scheduling of precast construction",
        "abstract": "Abstract   Despite a great deal of research into precast production scheduling published in academic journals worldwide, little attention has been given to environmental performance related to precast construction transportation and assembly scheduling problems. To address this issue, this paper studies the Just-in-Time (JIT) strategy for supply chain management of precast construction while considering time-dependent transportation time and on-site assembly time. There are two main contributions of our work. First, our analysis expands the current batch-scheduling model of minimizing earliness/tardiness penalties, by incorporating environmental impact considering the time-dependent transportation time and economic impact of resources wasted by waiting for on-site assembly. Second, we quantify the economic and environmental performance using our research objective, consisting of earliness/tardiness penalties, an additional transportation time penalty, and a resource waste penalty. The optimal results show that, compared with the supplieru0027s intuitive minimax optimization with deliveries on the earliest due date, there is an average 10.7% reduction of the objective value of a one-day assembly task by our proposed method. The results also show that the objective of achieving additional environmental performance conflicts with that of obtaining economic performance. However, sensitivity analysis further shows it is not always true to consider only additional environmental performance for the suppliers to achieve \u2018green\u2019 value. For a sustainable business, the customeru0027s service-JIT delivery should also be considered. Thus, when the policy makers assign importance weights to different objectives, they should fully consider both the economic and environmental impacts. The research contributes to batch delivery theory by expanding the approach to a time-dependent delivery model by considering both the economic and environmental effects. The method developed is of practical value for precast building projects to help in the successful implementation of sustainable development.",
        "keywords": "",
        "authors": [
            {
                "name": "Liulin Kong",
                "org": "School of Civil Engineering & Mechanics, Huazhong University of Science & Technology, Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong, China"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong, China"
            },
            {
                "name": "Hanbin Luo",
                "org": "School of Civil Engineering & Mechanics, Huazhong University of Science & Technology, China"
            },
            {
                "name": "Lieyun Ding",
                "org": "Institution of Construction Engineering, Huazhong University of Science & Technology, China"
            },
            {
                "name": "Xiaoling Zhang",
                "org": ""
            }
        ],
        "venue": "Journal of Cleaner Production",
        "year": 2018
    },
    "1N9Ktv4X": {
        "id": "1N9Ktv4X",
        "title": "Strain gradient differential quadrature beam finite elements",
        "abstract": "Abstract   In this paper, the superiorities of finite element method (FEM) and differential quadrature method (DQM) are blended to construct two types of beam elements corresponding to modified strain gradient -Bernoulli and Timoshenko beam models respectively. The two elements, being independent of shape functions and introducing three kinds of strain gradient effects, possess 3-DOFs (degrees of freedom) and 4-DOFs separately at each node. The Lagrange interpolation formula is employed to establish the trial functions of deflection and or rotation at Gauss-Lobatto quadrature points. To realize the inner-element compatibility condition, displacement parameters of quadrature points are converted into those of element nodes through a DQ-based mapping strategy. Total potential energy functional for each beam model is discretized in terms of nodal displacement parameters. The associated differential quadrature finite element formulations are derived by the minimum total potential energy principle. Specific expressions of element stiffness and mass matrices and nodal vector are provided. Numerical examples concerning with static bending, free vibration and buckling of macro/micro-beams are presented to demonstrate the availability of the proposed elements.",
        "keywords": "",
        "authors": [
            {
                "name": "Bo Zhang",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong, China"
            },
            {
                "name": "Bo Zhang",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong, China"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong, China"
            },
            {
                "name": "Liulin Kong",
                "org": "School of Civil Engineering & Mechanics, Huazhong University of Science & Technology, Wuhan, PR China"
            },
            {
                "name": "Jizhen Wang",
                "org": "PowerChina Turbine Technologies Co., Ltd., Chengdu, PR China"
            },
            {
                "name": "Huoming Shen",
                "org": "School of Mechanics and Engineering, Southwest Jiaotong University, Chengdu, PR China"
            }
        ],
        "venue": "Computers & Structures",
        "year": 2019
    },
    "BsULvx2m": {
        "id": "BsULvx2m",
        "title": "Measuring the effects of mergers and acquisitions on the economic performance of real estate developers",
        "abstract": "Real estate developers in China are using mergers and acquisitions (Mu0026As) to ensure their survival and competitiveness. However, no suitable method is yet available to assess whether such Mu0026As provide enhanced value for those involved. Using a hybrid method of data envelopment analysis (DEA) and Malmquist total factor productivity (TFP) indices, this paper evaluates the short and medium term effects of Mu0026As on acquirers\u2019 economic performance with a set of 32 Mu0026A cases occurring during 2000--2011 in China. The results of the analysis show that Mu0026As generally have a positive effect on acquirers\u2019 economic performance. Acquisitions on average experienced a steady growth in developer Malmquist TFP, a more progressive adoption of technology immediately after acquisition, a slight short-term decrease in technical efficiency after acquisition but followed by a marked increase in the longer term once the integration and synergy benefits were realised. However, there is no evidence to show whether developers achieved any short or long term scale efficiency improvements after Mu0026A. The findings of this study provide useful insights on developer Mu0026A performance from an efficiency and productivity perspective.",
        "keywords": "",
        "authors": [
            {
                "name": "Zhigang Jin",
                "org": "College of Architecture and Environment, Sichuan University, Chengdu 610065, China"
            },
            {
                "name": "Bo Xia",
                "org": "School of Civil Engineering and Built Environment, Queensland University of Technology, Gardens Point, Brisbane, Australia"
            },
            {
                "name": "Vera Li",
                "org": "School of Accountancy and Finance, The Hong Kong Polytechnic University, Hong Kong, China"
            },
            {
                "name": "Heng Li",
                "org": "Construction Virtual Prototyping Lab, Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong, China"
            },
            {
                "name": "Martin Skitmore",
                "org": "School of Civil Engineering and Built Environment, Queensland University of Technology, Gardens Point, Brisbane, Australia"
            }
        ],
        "venue": "International Journal of Strategic Property Management",
        "year": 2015
    },
    "djzGSvDf": {
        "id": "djzGSvDf",
        "title": "PATENT COOPERATIVE PATTERNS AND DEVELOPMENT TRENDS OF CHINESE CONSTRUCTION ENTERPRISES: A NETWORK ANALYSIS",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Botao Zhong",
                "org": "Huazhong University of Science and Technology"
            },
            {
                "name": "Yongjian Hei",
                "org": "Huazhong University of Science and Technology"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong, China"
            },
            {
                "name": "Timothy Rose",
                "org": "Faculty of Civil Engineering and Built Environment, Queensland University of Technology, Queensland, Australia"
            },
            {
                "name": "Hanbin Luo",
                "org": "Huazhong University of Science and Technology"
            }
        ],
        "venue": "Journal of Civil Engineering and Management",
        "year": 2019
    },
    "Q8oN8YIk": {
        "id": "Q8oN8YIk",
        "title": "Understanding the relationship between safety investment and safety performance of construction projects through agent-based modeling.",
        "abstract": "The construction industry in Hong Kong increased its safety investment by 300% in the past two decades; however, its accident rate has plateaued to around 50% for one decade. Against this backdrop, researchers have found inconclusive results on the causal relationship between safety investment and safety performance. Using agent-based modeling, this study takes an unconventional bottom-up approach to study safety performance on a construction site as an outcome of a complex system defined by interactions among a worksite, individual construction workers, and different safety investments. Instead of focusing on finding the absolute relationship between safety investment and safety performance, this study contributes to providing a practical framework to investigate how different safety investments interacting with different parameters such as human and environmental factors could affect safety performance. As a result, we could identify cost-effective safety investments under different construction scenarios for delivering optimal safety performance. ",
        "keywords": [
            "Agent-based modeling",
            "Construction industry",
            "Information technology",
            "Safety investment",
            "Safety performance"
        ],
        "authors": [
            {
                "name": "Miaojia Lu",
                "org": "Department of Civil and Environmental Engineering, The Hong Kong Polytechnic University, Hong Kong."
            },
            {
                "name": "Clara Man Cheung",
                "org": "Department of Civil and Environmental Engineering, The University of Maryland, United States."
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong."
            },
            {
                "name": "Shu-Chien Hsu",
                "org": "Department of Civil and Environmental Engineering, The Hong Kong Polytechnic University, Hong Kong. Electronic address: mark.hsu@polyu.edu.hk."
            }
        ],
        "venue": "Accident; analysis and prevention",
        "year": 2016
    },
    "WRfIsRCG": {
        "id": "WRfIsRCG",
        "title": "A deep learning-based method for detecting non-certified work on construction sites.",
        "abstract": "Abstract   The construction industry is a high hazard industry. Accidents frequently occur, and part of them are closely relate to workers who are not certified to carry out specific work. Although workers without a trade certificate are restricted entry to construction sites, few  ad-hoc  approaches have been commonly employed to check if a worker is carrying out the work for which they are certificated. This paper proposes a novel framework to check whether a site worker is working within the constraints of their certification. Our framework comprises key video clips extraction, trade recognition and worker competency evaluation. Trade recognition is a new proposed method through analyzing the dynamic spatiotemporal relevance between workers and non-worker objects. We also improved the identification results by analyzing, comparing, and matching multiple face images of each worker obtained from videos. The experimental results demonstrate the reliability and accuracy of our deep learning-based method to detect workers who are carrying out work for which they are not certified to facilitate safety inspection and supervision.",
        "keywords": "",
        "authors": [
            {
                "name": "Qi Fang",
                "org": "School of Civil Engineering & Mechanics, Huazhong University of Science & Technology, Wuhan, China"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong"
            },
            {
                "name": "Xiaochun Luo",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong"
            },
            {
                "name": "Lieyun Ding",
                "org": "School of Civil Engineering & Mechanics, Huazhong University of Science & Technology, Wuhan, China"
            },
            {
                "name": "Timothy M. Rose",
                "org": "School of Civil Engineering and Built Environment, Queensland University of Technology, Brisbane, Australia"
            },
            {
                "name": "Wangpeng An",
                "org": "Department of Computing, The Hong Kong Polytechnic University, Hong Kong"
            },
            {
                "name": "Yantao Yu",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong"
            }
        ],
        "venue": "Advanced Engineering Informatics",
        "year": 2018
    },
    "oGIdVXMG": {
        "id": "oGIdVXMG",
        "title": "Fall risk assessment of construction workers based on biomechanical gait stability parameters using wearable insole pressure system.",
        "abstract": "Abstract   Falls on the same level are a leading cause of non-fatal injuries in the construction industry, and loss of balance events are the primarily contributory risk factors associated with workers\u2019 fall injuries. Previous studies have indicated that changes in biomechanical gait stability parameters provide substantial safety gait metrics for assessing workers\u2019 fall risks. However, scant research has been conducted on changes in biomechanical gait stability parameters based on foot plantar pressure patterns to assess workers\u2019 fall risks. This research examined the changes in spatial foot regions and loss of balance events associated with biomechanical gait stability parameters based on foot plantar pressure patterns measured by wearable insole pressure system. To test the hypotheses of this study, ten asymptomatic participants conducted laboratory simulated loss of balance events which are often initiated by extrinsic fall risk factors. Our results found: (1) statistically significant differences in biomechanical gait stability parameters between spatial foot regions, especially with the peak pressure parameter; and (2) statistically significant differences in biomechanical gait stability parameters between loss of balance events when compared to normal gait (baseline), especially with the pressure-time integral parameter. Overall, the findings of this study not only provide useful safety gait metrics for early detection of specific spatial foot regions but also allow safety managers to understand the mechanism of loss of balance events in order to implement proactive fall-prevention strategies.",
        "keywords": "",
        "authors": [
            {
                "name": "Maxwell Fordjour Antwi-Afari",
                "org": "Department of Building and Real Estate, Faculty of Construction and Environment, Hong Kong Polytechnic University, Room No. ZN1002, Hung Hom, Kowloon, Hong Kong Special Administrative Region"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, Faculty of Construction and Environment, Hong Kong Polytechnic University, Room No. ZS734, Hung Hom, Kowloon, Hong Kong Special Administrative Region"
            }
        ],
        "venue": "Advanced Engineering Informatics",
        "year": 2018
    },
    "CmzAcYiz": {
        "id": "CmzAcYiz",
        "title": "Sensing and warning-based technology applications to improve occupational health and safety in the construction industry: A literature review",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Maxwell Fordjour Antwi-Afari",
                "org": "Department of Building and Real Estate, Hong Kong Polytechnic University, Kowloon, Hong Kong"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, Hong Kong Polytechnic University, Kowloon, Hong Kong"
            },
            {
                "name": "Johnny Kwok-Wai Wong",
                "org": "School of Built Environment, University of Technology, Sydney, Australia"
            },
            {
                "name": "Olugbenga Timo Oladinrin",
                "org": "Department of Building and Real Estate, Hong Kong Polytechnic University, Kowloon, Hong Kong"
            },
            {
                "name": "Janet Xin Ge",
                "org": "School of Built Environment, Faculty of Design, Architecture and Building, University of Technology, Sydney, Australia"
            },
            {
                "name": "JoonOh Seo",
                "org": "Department of Building and Real Estate, Hong Kong Polytechnic University, Kowloon, Hong Kong"
            },
            {
                "name": "Arnold Yu Lok Wong",
                "org": "Department of Rehabilitation Sciences, Faculty of Health and Social Sciences, Hong Kong Polytechnic University, Kowloon, Hong Kong"
            }
        ],
        "venue": "Engineering, Construction and Architectural Management",
        "year": 2019
    },
    "8d5t6q8N": {
        "id": "8d5t6q8N",
        "title": "Developing an IFC-Based Database for Construction Quality Evaluation",
        "abstract": "Quality evaluation and control are increasingly important concerns in construction projects. Construction quality evaluation, as a systematic method, must be discussed in light of quality information extraction and storage, while a traditional construction quality control program cannot meet these requirements. In moving beyond quality indicators to evaluate quality performance that is comparable across construction entities, two fundamental factors must be considered: quality information standardization and multiquality data integration. The purpose of this study is to extend the interoperability of a construction quality database in the evaluation process by employing the industry foundation classes (IFC) data model. Taking a cast-in-place steel-concrete structure as an example, this study explores the implementation of building information modeling (BIM) in quality management and proposes integrated solutions to improve current quality management processes with the assistance of an IFC-based working environment. To better utilize the performance of the BIM model and database on construction quality control, various BIM-based evaluation frameworks are proposed. Also, this paper discusses how these IFC and neutral network models operate together to facilitate construction quality management. Project participants can better understand quality progress and collaborate more effectively, thanks to a visualized data format. The objective of evaluating the proposed model is to understand the effectiveness of an IFC-based database when implemented in practice. A questionnaire was developed considering the opinions of construction firms and design institutes regarding identified factors. In designing an IFC-based quality database, the method proposed in this study reduces the complexity of the database substantially and improves quality evaluation efficiency.",
        "keywords": "",
        "authors": [
            {
                "name": "Zhao Xu",
                "org": "Department of Civil Engineering, Southeast University, Nanjing 210096, China"
            },
            {
                "name": "Ting Huang",
                "org": "Department of Building and Real Estate, Hong Kong Polytechnic University, Hong Kong"
            },
            {
                "name": "Bingjing Li",
                "org": "Department of Civil Engineering, Southeast University, Nanjing 210096, China"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, Hong Kong Polytechnic University, Hong Kong"
            },
            {
                "name": "Qiming Li",
                "org": "Department of Civil Engineering, Southeast University, Nanjing 210096, China"
            }
        ],
        "venue": "Advances in Civil Engineering",
        "year": 2018
    },
    "rpjX9PzV": {
        "id": "rpjX9PzV",
        "title": "Developing a green building evaluation standard for interior decoration: A case study of China",
        "abstract": "Abstract   Green building development has become a worldwide popular topic in recent years. As an indispensable phase of a building project, interior decoration has an unavoidable impact on the environment and public health. Currently, there have been several green building evaluation standards for interior decoration. However, there is no specific evaluation standard, which is complied with the domestic situation of China, for green interior decoration. This study aims to develop an assessment standard for green interior decoration in the context of China. To start with, a comprehensive review of existing green building rating tools and focus group meetings were held to filter the assessment items and to determine the basic framework of the proposed assessment standard. Eight assessment aspects, including seven basic aspects and one bonus aspect, were identified to formulate the structure of the proposed standard. Then, methods of analytic hierarchy process and relative significance index were employed to evaluate the weight of each aspect and to determine the assigned score for each assessment item. Finally, an assessment standard for green interior decoration, which can be applied to the completion acceptance assessment and the operation management assessment, was developed for evaluating and guiding green interior decoration projects. Three aspects, namely indoor environment quality, material saving and utilization, and energy saving and utilization, were identified to be the most significant ones. A real-life project was further selected to validate the feasibility of the proposed evaluation standard.",
        "keywords": "",
        "authors": [
            {
                "name": "Zezhou Wu",
                "org": "Department of Construction Management and Real Estate, College of Civil Engineering, Shenzhen University, Shenzhen, China"
            },
            {
                "name": "Zezhou Wu",
                "org": "Department of Construction Management and Real Estate, College of Civil Engineering, Shenzhen University, Shenzhen, China"
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Kowloon, Hong Kong"
            },
            {
                "name": "Yong Feng",
                "org": "Gasu Adorn Design Engineering, Shenzhen, China"
            },
            {
                "name": "Xiaochun Luo",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Kowloon, Hong Kong"
            },
            {
                "name": "Qiaohui Chen",
                "org": "Department of Computing, The Hong Kong Polytechnic University, Kowloon, Hong Kong"
            }
        ],
        "venue": "Building and Environment",
        "year": 2019
    },
    "PBBcGZcG": {
        "id": "PBBcGZcG",
        "title": "Identifying and contextualising the motivations for BIM implementation in construction projects: An empirical study in China",
        "abstract": "Abstract   Grounded in institutional theory and the innovation diffusion literature, this paper identifies the motivations of designers and general contractors to implement BIM in construction projects, and investigates how different motivations are impacted by organisational BIM capability and other contextual factors. Results of factor analysis with survey data collected from China provide support for the theoretically developed motivation model which classifies BIM implementation motivations into four categories:  image motives ,  reactive motives ,  project-based economic motives ,  cross-project economic motives . Hierarchical regression results suggest that although project participants will have stronger economic motivations to improve project performances as their BIM capability matures, this increase in economic motivations does not necessarily require a parallel decrease of desires to improve social image. Regression results also suggest that BIM implementation motivations relate to organisational ownership type and project characteristics. The findings contribute to a broadened understanding of the multi-dimensionality and dynamics of construction organisationsu0027 innovation implementation motivations.",
        "keywords": "",
        "authors": [
            {
                "name": "Dongping Cao",
                "org": ""
            },
            {
                "name": "Dongping Cao",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong, China"
            },
            {
                "name": "Guangbin Wang",
                "org": "Department of Construction Management and Real Estate, School of Economics and Management, Tongji University, Shanghai 200092, China"
            },
            {
                "name": "Ting Huang",
                "org": "Department of Building and Real Estate, The Hong Kong Polytechnic University, Hong Kong, China"
            }
        ],
        "venue": "International Journal of Project Management",
        "year": 2017
    },
    "dYOv0l0p": {
        "id": "dYOv0l0p",
        "title": "Linking the Motivations and Practices of Design Organizations to Implement Building Information Modeling in Construction Projects: Empirical Study in China",
        "abstract": "AbstractDrawing on institutional theory and the innovation diffusion literature, this paper investigates how design organizations\u2019 building information modeling (BIM) implementation practices in construction projects are associated with their BIM implementation motivations and related project contextual factors. These associations are empirically tested with survey data collected from BIM-based construction projects in China, and the examined BIM implementation motivations include image motives, reactive motives, project-based economic motives, and cross-project economic motives. Hierarchical regression analysis results illustrate that design organizations\u2019 project BIM implementation practices are significantly impacted by project contextual factors such as client/owner support, and that after controlling for the project contextual factors the higher weights of project-based economic motives and image motives are both significantly associated with higher levels of BIM implementation. By contrast, reactive...",
        "keywords": "",
        "authors": [
            {
                "name": "Dongping Cao",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Guangbin Wang",
                "org": ""
            },
            {
                "name": "Wenjuan Zhang",
                "org": ""
            }
        ],
        "venue": "Journal of Management in Engineering",
        "year": 2016
    },
    "q8Na3Hch": {
        "id": "q8Na3Hch",
        "title": "Impacts of building information modeling (BIM) implementation on design and construction performance: a resource dependence theory perspective",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Dongping Cao",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Guangbin Wang",
                "org": ""
            }
        ],
        "venue": "Frontiers of Engineering Management",
        "year": 2017
    },
    "UvBAEsFT": {
        "id": "UvBAEsFT",
        "title": "Relationship Network Structure and Organizational Competitiveness: Evidence from BIM Implementation Practices in the Construction Industry",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Dongping Cao",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Guangbin Wang",
                "org": ""
            },
            {
                "name": "Xiaochun Luo",
                "org": ""
            },
            {
                "name": "Dan Tan",
                "org": ""
            }
        ],
        "venue": "Journal of Management in Engineering",
        "year": 2018
    },
    "8A9GUTTP": {
        "id": "8A9GUTTP",
        "title": "Dynamics of Collaborative Networks between Contractors and Subcontractors in the Construction Industry: Evidence from National Quality Award Projects in China",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Yixuan Tang",
                "org": "Ph.D. Candidate, Dept. of Construction Management and Real Estate, School of Economics and Management, Tongji Univ., 1239 Siping Rd., Shanghai 200092, China."
            },
            {
                "name": "Guangbin Wang",
                "org": "Professor, Dept. of Construction Management and Real Estate, School of Economics and Management, Tongji Univ., 1239 Siping Rd., Shanghai 200092, China."
            },
            {
                "name": "Heng Li",
                "org": "Chair Professor, Dept. of Building and Real Estate, Hong Kong Polytechnic Univ., 11 Yuk Choi Rd., Hung Hom, Kowloon, Hong Kong, China."
            },
            {
                "name": "Dongping Cao",
                "org": "Assistant Professor, Dept. of Construction Management and Real Estate, School of Economics and Management, Tongji Univ., 1239 Siping Rd., Shanghai 200092, China (corresponding author). ORCID: ."
            }
        ],
        "venue": "Journal of Construction Engineering and Management-asce",
        "year": 2018
    },
    "tLR1oxYm": {
        "id": "tLR1oxYm",
        "title": "Impacts of Isomorphic Pressures on BIM Adoption in Construction Projects",
        "abstract": "",
        "keywords": [
            "innovation",
            "institutional theory",
            "construction management"
        ],
        "authors": [
            {
                "name": "dongping cao",
                "org": ""
            },
            {
                "name": "heng li",
                "org": ""
            },
            {
                "name": "guangbin wang",
                "org": ""
            }
        ],
        "venue": "Journal of Construction Engineering and Management-asce",
        "year": 2014
    },
    "hyZXBl4M": {
        "id": "hyZXBl4M",
        "title": "A framework for analysing system intelligence of the building control system: a study of the integrated building management system",
        "abstract": "",
        "keywords": [
            "smart systems",
            "intelligent building"
        ],
        "authors": [
            {
                "name": "johnny wong",
                "org": ""
            },
            {
                "name": "heng li",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2009
    },
    "69z6d6FB": {
        "id": "69z6d6FB",
        "title": "Evaluating the system intelligence of the intelligent building systems : Part 2 : construction and validation of analytical models",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "johnny wong",
                "org": ""
            },
            {
                "name": "heng li",
                "org": ""
            },
            {
                "name": "jenkin lai",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2008
    },
    "dJdcBCBX": {
        "id": "dJdcBCBX",
        "title": "Evaluating the system intelligence of the intelligent building systems : Part 1 : Development of key intelligent indicators and conceptual analytical framework",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "johnny wong",
                "org": ""
            },
            {
                "name": "heng li",
                "org": ""
            },
            {
                "name": "jenkin lai",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2008
    },
    "ATLTVpcG": {
        "id": "ATLTVpcG",
        "title": "A framework for analyzing system intelligence of the building control system : a study of the integrated building management system",
        "abstract": "",
        "keywords": [
            "intelligent building",
            "smart systems"
        ],
        "authors": [
            {
                "name": "johnny wong",
                "org": ""
            },
            {
                "name": "heng li",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2009
    },
    "wGoEfiqF": {
        "id": "wGoEfiqF",
        "title": "The adjustment of leadership styles in intercultural workplace \u2013 some evidences from the multinational construction companies in Hong Kong",
        "abstract": "",
        "keywords": [
            "leadership styles"
        ],
        "authors": [
            {
                "name": "johnny wong",
                "org": ""
            },
            {
                "name": "philco n k wong",
                "org": ""
            },
            {
                "name": "heng li",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2006
    },
    "Dhg2YgZW": {
        "id": "Dhg2YgZW",
        "title": "Measuring the level of \u2018intelligence\u2019 of a smart building system in an intelligent building : the analytic network process (ANP)",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "johnny wong",
                "org": ""
            },
            {
                "name": "heng li",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2007
    },
    "sZBfCH78": {
        "id": "sZBfCH78",
        "title": "Evaluating the system intelligence of the intelligent building systems: Part 1: Development of key intelligent indicators and conceptual analytical framework",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "johnny wong",
                "org": ""
            },
            {
                "name": "heng li",
                "org": ""
            },
            {
                "name": "jenkin lai",
                "org": ""
            }
        ],
        "venue": "Automation in Construction",
        "year": 2008
    },
    "K4G7SEMH": {
        "id": "K4G7SEMH",
        "title": "Evaluating the system intelligence of the intelligent building systems: Part 2: Construction and validation of analytical models",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "johnny wong",
                "org": ""
            },
            {
                "name": "heng li",
                "org": ""
            },
            {
                "name": "jenkin lai",
                "org": ""
            }
        ],
        "venue": "Automation in Construction",
        "year": 2008
    },
    "1eOQxCpo": {
        "id": "1eOQxCpo",
        "title": "Development of a conceptual model for the selection of intelligent building systems",
        "abstract": "",
        "keywords": [
            "conceptual model",
            "decision maker",
            "conceptual framework",
            "intelligent building"
        ],
        "authors": [
            {
                "name": "johnny wong",
                "org": ""
            },
            {
                "name": "heng li",
                "org": ""
            }
        ],
        "venue": "Building and Environment",
        "year": 2006
    },
    "cO561IRn": {
        "id": "cO561IRn",
        "title": "Multiuser virtual safety training system for tower crane dismantlement",
        "abstract": "",
        "keywords": [
            "disassembly",
            "virtual reality"
        ],
        "authors": [
            {
                "name": "heng li",
                "org": ""
            },
            {
                "name": "greg chan",
                "org": ""
            },
            {
                "name": "martin skitmore",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2012
    },
    "hsbb0yJb": {
        "id": "hsbb0yJb",
        "title": "Practical framework for measuring performance of international construction firms",
        "abstract": "",
        "keywords": [
            "benchmarking",
            "performance measurement",
            "balanced scorecard",
            "internationalization"
        ],
        "authors": [
            {
                "name": "zhigang jin",
                "org": ""
            },
            {
                "name": "fei deng",
                "org": ""
            },
            {
                "name": "heng li",
                "org": ""
            },
            {
                "name": "martin skitmore",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2013
    },
    "8fV5pCXO": {
        "id": "8fV5pCXO",
        "title": "A 4D automatic simulation tool for construction resource planning: A case study",
        "abstract": "",
        "keywords": [
            "critical path method"
        ],
        "authors": [
            {
                "name": "heng li",
                "org": ""
            },
            {
                "name": "greg chan",
                "org": ""
            },
            {
                "name": "martin skitmore",
                "org": ""
            },
            {
                "name": "ting huang",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2015
    },
    "iV6eYxzA": {
        "id": "iV6eYxzA",
        "title": "From IKEA Model to the Lean Construction Concept: A Solution to Implementation",
        "abstract": "",
        "keywords": [
            "construction industry"
        ],
        "authors": [
            {
                "name": "heng li",
                "org": ""
            },
            {
                "name": "h l guo",
                "org": ""
            },
            {
                "name": "yan li",
                "org": ""
            },
            {
                "name": "martin skitmore",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2014
    },
    "PcytjwuJ": {
        "id": "PcytjwuJ",
        "title": "Proactive training system for safe and efficient precast installation",
        "abstract": "",
        "keywords": [
            "construction safety",
            "real time location system"
        ],
        "authors": [
            {
                "name": "heng li",
                "org": ""
            },
            {
                "name": "miaojia lu",
                "org": ""
            },
            {
                "name": "greg chan",
                "org": ""
            },
            {
                "name": "martin skitmore",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2015
    },
    "zpRAIx3X": {
        "id": "zpRAIx3X",
        "title": "Chirp-spread-spectrum-based real time location system for construction safety management: A case study",
        "abstract": "Observing the working procedure of construction workers is an effective means of maintaining the safety performance of a construction project. It is also difficult to achieve due to a high worker-to-safety-officer ratio. There is an imminent need for the development of a tool to assist in the real-time monitoring of workers, in order to reduce the number of construction accidents. The development and application of a real time locating system (RTLS) based on the Chirp Spread Spectrum (CSS) technique is described in this paper for tracking the real-time position of workers on construction sites. Experiments and tests were carried out both on- and off-site to verify the accuracy of static and dynamic targets by the system, indicating an average error of within one metre. Experiments were also carried out to verify the ability of the system to identify workers\u2019 unsafe behaviours. Wireless data transfer was used to simplify the deployment of the system. The system was deployed in a public residential construction project and proved to be quick and simple to use. The cost of the developed system is also reported to be reasonable (around 1800USD) in this study and is much cheaper than the cost of other RTLS. In addition, the CCS technique is shown to provide an economical solution with reasonable accuracy compared with other positioning systems, such as ultra wideband. The study verifies the potential of the CCS technique to provide an effective and economical aid in the improvement of safety management in the construction industry.",
        "keywords": [
            "chirp spread spectrum"
        ],
        "authors": [
            {
                "name": "heng li",
                "org": ""
            },
            {
                "name": "greg chan",
                "org": ""
            },
            {
                "name": "ting huang",
                "org": ""
            },
            {
                "name": "martin skitmore",
                "org": ""
            },
            {
                "name": "y e tao terry",
                "org": ""
            },
            {
                "name": "eric luo",
                "org": ""
            },
            {
                "name": "jacky chung",
                "org": ""
            },
            {
                "name": "x s chan",
                "org": ""
            },
            {
                "name": "y f li",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2015
    },
    "LbN8KQ1G": {
        "id": "LbN8KQ1G",
        "title": "Virtual prototyping for planning bridge construction",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "heng li",
                "org": ""
            },
            {
                "name": "neo k y chan",
                "org": ""
            },
            {
                "name": "ting huang",
                "org": ""
            },
            {
                "name": "martin skitmore",
                "org": ""
            },
            {
                "name": "jay yang",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2012
    },
    "wycFggt2": {
        "id": "wycFggt2",
        "title": "Rethinking prefabricated construction management using the VP-based IKEA model in Hong Kong",
        "abstract": "",
        "keywords": [
            "construction industry",
            "construction management",
            "manufacturing industry",
            "design optimization",
            "prefabricated construction"
        ],
        "authors": [
            {
                "name": "heng li",
                "org": "hong kong polytechnic university"
            },
            {
                "name": "h l guo",
                "org": "hong kong polytechnic university"
            },
            {
                "name": "martin skitmore",
                "org": "queensland university of technology"
            },
            {
                "name": "ting huang",
                "org": "hong kong polytechnic university"
            },
            {
                "name": "k y n chan",
                "org": "hong kong polytechnic university"
            },
            {
                "name": "greg chan",
                "org": "hong kong polytechnic university"
            }
        ],
        "venue": "Construction Management and Economics",
        "year": 2011
    },
    "owf74oYx": {
        "id": "owf74oYx",
        "title": "Integrating real time positioning systems to improve blind lifting and loading crane operations",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "heng li",
                "org": ""
            },
            {
                "name": "greg chan",
                "org": ""
            },
            {
                "name": "martin skitmore",
                "org": ""
            }
        ],
        "venue": "Construction Management and Economics",
        "year": 2013
    },
    "bAakmiNW": {
        "id": "bAakmiNW",
        "title": "The use of virtual prototyping to rehearse the sequence of construction work involving mobile cranes",
        "abstract": "",
        "keywords": [
            "sequencing",
            "project planning",
            "simulation"
        ],
        "authors": [
            {
                "name": "heng li",
                "org": ""
            },
            {
                "name": "neo k y chan",
                "org": ""
            },
            {
                "name": "martin skitmore",
                "org": ""
            }
        ],
        "venue": "Construction Innovation: Information, Process, Management",
        "year": 2013
    },
    "N8nYt4x4": {
        "id": "N8nYt4x4",
        "title": "Life-Cycle Management of Construction Projects Based on Virtual Prototyping Technology",
        "abstract": "",
        "keywords": [
            "life cycle management",
            "communication",
            "construction management",
            "information management",
            "life cycles"
        ],
        "authors": [
            {
                "name": "h l guo",
                "org": ""
            },
            {
                "name": "heng li",
                "org": ""
            },
            {
                "name": "martin skitmore",
                "org": ""
            }
        ],
        "venue": "Journal of Management in Engineering",
        "year": 2009
    },
    "4sA1C4zd": {
        "id": "4sA1C4zd",
        "title": "Identification of Biomechanical Risk Factors for the Development of Lower-Back Disorders during Manual Rebar Tying",
        "abstract": "AbstractHigh prevalence of musculoskeletal disorders among construction workers pose challenges to the productivity and occupational health of the construction industry. To mitigate the risk of musculoskeletal disorders, construction managers need to deepen their understanding of the physical and biomechanical demands of various construction tasks so that appropriate policies and preventive measures can be implemented. Among various construction trades, rebar workers are highly susceptible to lower-back disorders (LBDs) given the physically demanding nature of their work tasks. In particular, rebar tying is considered to be closely related to LBDs because it exposes workers to multiple ergonomic risk factors (repetitive works in prolonged static and awkward postures). The objective of the current study was to compare the differences in lumbar biomechanics during three typical rebar tying postures: stooping, one-legged kneeling, and squatting. Biomechanical variables including trunk muscle activity and tru...",
        "keywords": "",
        "authors": [
            {
                "name": "Waleed Umer",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Grace Pui Yuk Szeto",
                "org": ""
            },
            {
                "name": "Arnold Yu Lok Wong",
                "org": ""
            }
        ],
        "venue": "Journal of Construction Engineering and Management-asce",
        "year": 2017
    },
    "uKmS7E8M": {
        "id": "uKmS7E8M",
        "title": "Low-Cost Ergonomic Intervention for Mitigating Physical and Subjective Discomfort during Manual Rebar Tying",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Waleed Umer",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Grace Pui Yuk Szeto",
                "org": ""
            },
            {
                "name": "Arnold Y.L. Wong",
                "org": ""
            }
        ],
        "venue": "Journal of Construction Engineering and Management-asce",
        "year": 2017
    },
    "uPDOW6UF": {
        "id": "uPDOW6UF",
        "title": "Proactive Safety Measures: Quantifying the Upright Standing Stability after Sustained Rebar Tying Postures",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Waleed Umer",
                "org": "Ph.D. Candidate, Dept. of Building and Real Estate, Hong Kong Polytechnic Univ., Room # ZN1002, Hung Hom, Kowloon, Hong Kong SAR (corresponding author). ORCID: ."
            },
            {
                "name": "Heng Li",
                "org": "Chair Professor, Dept. of Building and Real Estate, Hong Kong Polytechnic Univ., Room # ZS734, Hung Hom, Kowloon, Hong Kong SAR."
            },
            {
                "name": "Grace Pui Yuk Szeto",
                "org": "Associate Professor, Dept. of Rehabilitation Sciences, Hong Kong Polytechnic Univ., Room # ST505, Hung Hom, Kowloon, Hong Kong SAR."
            },
            {
                "name": "Arnold Y.L. Wong",
                "org": "Assistant Professor, Dept. of Rehabilitation Sciences, Hong Kong Polytechnic Univ., Room # ST512, Hung Hom, Kowloon, Hong Kong SAR."
            }
        ],
        "venue": "Journal of Construction Engineering and Management-asce",
        "year": 2018
    },
    "AgDpVKHJ": {
        "id": "AgDpVKHJ",
        "title": "Model of Equipment Sharing between Contractors on Construction Projects",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Zhi Liu",
                "org": "Ph.D. Candidate, School of Automation, Huazhong Univ. of Science and Technology, Wuhan 430074, China."
            },
            {
                "name": "Hongwei Wang",
                "org": "Professor, School of Management, Huazhong Univ. of Science and Technology, Wuhan 430074, China (corresponding author)."
            },
            {
                "name": "Heng Li",
                "org": "Professor, Dept. of Building and Real Estate, Hong Kong Polytechnic Univ., Kowloon 999077, Hong Kong."
            }
        ],
        "venue": "Journal of Construction Engineering and Management-asce",
        "year": 2018
    },
    "yMQVVvJz": {
        "id": "yMQVVvJz",
        "title": "Real-Time Alarming, Monitoring, and Locating for Non-Hard-Hat Use in Construction",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Hong Zhang",
                "org": "Professor, Institute of Construction Management, College of Civil Engineering and Architecture, Zhejiang Univ., 866 Yuhangtang Rd., Hangzhou 310058, China."
            },
            {
                "name": "Xuzhong Yan",
                "org": "Ph.D. Candidate, Institute of Construction Management, College of Civil Engineering and Architecture, Zhejiang Univ., 866 Yuhangtang Rd., Hangzhou 310058, China (corresponding author). ORCID: ."
            },
            {
                "name": "Heng Li",
                "org": "Chair Professor, Dept. of Building and Real Estate, Faculty of Construction and Environment, Hong Kong Polytechnic Univ., 11 Yuk Choi Rd., Hung Hom, Kowloon, Hong Kong 999077, China."
            },
            {
                "name": "Rui Jin",
                "org": "Professorate Senior Engineer, Zhejiang Construction Engineering Group Co., Ltd., 232 Wensan Rd., Hangzhou, Zhejiang Province 310058, China."
            },
            {
                "name": "HongFeng Fu",
                "org": "M.S. Student, Institute of Construction Management, College of Civil Engineering and Architecture, Zhejiang Univ., 866 Yuhangtang Rd., Hangzhou 310058, China."
            }
        ],
        "venue": "Journal of Construction Engineering and Management-asce",
        "year": 2019
    },
    "qrBWwf8L": {
        "id": "qrBWwf8L",
        "title": "Pavement maintenance-focused decision analysis on concession periods of PPP highway projects",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Hong Zhang",
                "org": ""
            },
            {
                "name": "Rui Jin",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Miroslaw J. Skibniewski",
                "org": ""
            }
        ],
        "venue": "Journal of Management in Engineering",
        "year": 2018
    },
    "7JrHrJVB": {
        "id": "7JrHrJVB",
        "title": "Identification of potential biomechanical risk factors for low back disorders during repetitive rebar lifting",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Maxwell Fordjour Antwi-Afari",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "David J. Edwards",
                "org": ""
            },
            {
                "name": "Erika Parn",
                "org": ""
            },
            {
                "name": "De-Graft Owusu-Manu",
                "org": ""
            },
            {
                "name": "JoonOh Seo",
                "org": ""
            },
            {
                "name": "Arnold Yu Lok Wong",
                "org": ""
            }
        ],
        "venue": "Construction Innovation: Information, Process, Management",
        "year": 2018
    },
    "j1udGpr8": {
        "id": "j1udGpr8",
        "title": "ANP Experiment for Demolition Plan Evaluation",
        "abstract": "",
        "keywords": [
            "assessment",
            "analytical techniques"
        ],
        "authors": [
            {
                "name": "zhen chen",
                "org": ""
            },
            {
                "name": "arham b abdullah",
                "org": ""
            },
            {
                "name": "chimay j anumba",
                "org": ""
            },
            {
                "name": "heng li",
                "org": ""
            }
        ],
        "venue": "Journal of Construction Engineering and Management-asce",
        "year": 2013
    },
    "s0UYiQ6B": {
        "id": "s0UYiQ6B",
        "title": "Construction Material Safety-Stock Determination Under Nonstationary Stochastic Demand and Random Supply Yield.",
        "abstract": "Nonstationary stochastic demand and random supply yield have led to a great challenge in construction material management. Appropriate safety stocks can cope with uncertainty in both demand and supply yield, and improve the construction cost and productivity significantly. But the safety stock is usually determined by planneru0027s experience or rough evaluation in management practice, which results in overstock or understock situations frequently. For changing this situation, this paper focuses on analysis of the stochastic inventory control problem of construction material, and develops a general safety-stock determination approach under nonstationary stochastic demand and random supply yield. Based on the linear-order release rule and modified base-stock definition, the inventory balance equation is developed. Then, a coverage random variable, which incorporates the complete information of outstanding orders, is defined to represent the outflows and inflows to stock over risk periods. Meanwhile, the fixed-point iteration method is adopted to calculate the time-varying safety-stock level under predefined service-level (nonstockout probability) constraint. Finally, a numerical analysis is conducted to investigate the relative performance of the proposed safety-stock approach and days of supply rule. The result demonstrates a considerable service improvement and inventory decrease of the safety-stock approach.",
        "keywords": [],
        "authors": [
            {
                "name": "Hui Lu",
                "org": ""
            },
            {
                "name": "Hongwei Wang",
                "org": ""
            },
            {
                "name": "Yong Xie",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            }
        ],
        "venue": "IEEE Trans. Engineering Management",
        "year": 2016
    },
    "Fz5d8S0R": {
        "id": "Fz5d8S0R",
        "title": "Discussion of \u201cFuzzy Analytical Hierarchy Process Risk Assessment Approach for Joint Venture Construction Projects in China\u201d by Guomin Zhang and Patrick X. W. Zou",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "zhen chen",
                "org": ""
            },
            {
                "name": "heng li",
                "org": ""
            }
        ],
        "venue": "Journal of Construction Engineering and Management-asce",
        "year": 2010
    },
    "jGoxglWL": {
        "id": "jGoxglWL",
        "title": "A Study of Intelligent Stadiums: the City of Manchester Stadium",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "zhen chen",
                "org": ""
            },
            {
                "name": "ju hong",
                "org": ""
            },
            {
                "name": "heng li",
                "org": ""
            },
            {
                "name": "qian xu",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2006
    },
    "zIqPs9Mi": {
        "id": "zIqPs9Mi",
        "title": "Managing the environment",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "zhen chen",
                "org": ""
            },
            {
                "name": "heng li",
                "org": ""
            },
            {
                "name": "rodney turner",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2007
    },
    "stN0TOHn": {
        "id": "stN0TOHn",
        "title": "Discussion of \"Safety Risk Identification",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "dongping fang",
                "org": ""
            },
            {
                "name": "shouqing wang",
                "org": ""
            },
            {
                "name": "mengdong dai",
                "org": ""
            },
            {
                "name": "xiaoquan lv",
                "org": ""
            },
            {
                "name": "zhen chen",
                "org": ""
            },
            {
                "name": "heng li",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2009
    },
    "KSWkp6m2": {
        "id": "KSWkp6m2",
        "title": "Discussion of \"ISO 14000 and the Construction Industry: Survey in China\"",
        "abstract": "",
        "keywords": [
            "china",
            "construction industry"
        ],
        "authors": [
            {
                "name": "zhen chen",
                "org": ""
            },
            {
                "name": "heng li",
                "org": ""
            }
        ],
        "venue": "Journal of Management in Engineering",
        "year": 2005
    },
    "MBfo0lpw": {
        "id": "MBfo0lpw",
        "title": "Discussion of \"Safety Risk Identification and Assessment for Beijing Olympic Venues Construction\"",
        "abstract": "",
        "keywords": [
            "risk management",
            "construction management",
            "assessment",
            "china"
        ],
        "authors": [
            {
                "name": "zhen chen",
                "org": ""
            },
            {
                "name": "heng li",
                "org": ""
            }
        ],
        "venue": "Journal of Management in Engineering",
        "year": 2009
    },
    "1nekSw1J": {
        "id": "1nekSw1J",
        "title": "Different surgical methods in treatment of secondary glaucoma due to intumescent cataract",
        "abstract": "AIM:To investigate the method in treatment of secondary glaucoma due to intumescent cataract.\u00b7METHODS: Two kinds of surgical methods were used in thirty-six cases (36 eyes) of secondary glaucoma due to intumescent cataract respectively. Cataract extraction through small incision combined with intraocular lens implantation (two-manner operation) was carried out in 16 cases with open chamber angle over 180 degrees. Cataract extraction through small incision combined with intraocular lens implantation and trabeculectomy (three-manner operation) was carried out in 20 cases with open chamber angle less than 180 degrees. \u00b7RESULTS: In 16 cases with two-manner operation,vision was 0.05-0.2 in 5 cases (31%),0.3-0.4 in 9 cases (56%),\u22650.5 in 2 cases (13%),the maximum postoperative intraocular pressure was 20.55mmHg,the minimum value was 12.23mmHg,and the mean value was 16.46mmHg. In 20 cases with three-manner operation,vision was 0.05-0.2 in 9 cases (45%),0.3-0.4 in 8 cases (40%),\u22650.5 in 3 cases (15%). In 18 of the 20 cases,the maximum postoperative intraocular pressure was 20.55mmHg,the minimum value was 13.35mmHg,and the mean value was 16.48 mmHg. In 2 of the 20 cases,the postoperative intraocular pressure was 32.97-25.81mmHg,and was controlled to 14.57mmHg after 5g/L timolol application one times a day.\u00b7CONCLUSION: Both of the two surgical methods have good long term effects in treatment of secondary glaucoma due to intumescent cataract.",
        "keywords": [
            "glaucoma",
            "operation",
            "cataract"
        ],
        "authors": [
            {
                "name": "Bo Long",
                "org": " Department of Ophthalmology,Central Hospital of Suining City,Suining ,Sichuan Province,China"
            },
            {
                "name": "Heng Li",
                "org": " Department of Ophthalmology,Central Hospital of Suining City,Suining ,Sichuan Province,China"
            },
            {
                "name": "Zhi-Jin Tang",
                "org": " Department of Ophthalmology,Central Hospital of Suining City,Suining ,Sichuan Province,China"
            },
            {
                "name": "Xu Yang",
                "org": " Department of Ophthalmology,Central Hospital of Suining City,Suining ,Sichuan Province,China"
            }
        ],
        "venue": "International Journal of Ophthalmology",
        "year": 2009
    },
    "aZNDkanO": {
        "id": "aZNDkanO",
        "title": "Observation of vitrectomy and Nd:YAG 532nm laser on treatment of retinal vasculitis",
        "abstract": "\ue624AIM:To report the effects of the vitrectomy combined with Nd:YAG 532nm laser on treatment of retinal vasculitis.\ue624METHODS:Data of 36 cases(36 eyes)with retinal vasculitis undergoing vitrectomy and Nd:YAG 532nm laser treatment were analyzed retrospectively.\ue624RESULTS:Two cases were retinal arteritis,4 cases were retinal phlebitis and 30 cases' damnification were on both artery and vein of retina in 36 cases.The damnification of lens was in 1 case,iatrogenic retinal hole was in 6 cases and dialysis of ora serrata was in 3 cases in operation.2 cases were of retina detachment again,2 cases of hyphema and 9 cases of ocular hypertension after operation.The best visual acuity of 36 cases were improved,which was 0.02 to 0.1 in 2 cases(6%),0.12 to 0.4 in 22 cases(61%)and 0.5 to 1.0 in 12 cases(33%).\ue624CONCLUSION:Vitrectomy combined with Nd:YAG 532nm laser is an effective treatment for retinal vasculitis.\ue624",
        "keywords": [
            "vitrectomy",
            "Nd:YAG 532nm laser",
            "retinal vasculitis"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": "Department of Ophthalmology"
            },
            {
                "name": "Xue Mi",
                "org": "Digestive Endoscopy Center,Central Hospital of Suining,Suining ,Sichuan Province,China"
            }
        ],
        "venue": "International Eye Science",
        "year": 2012
    },
    "iqyI77Vc": {
        "id": "iqyI77Vc",
        "title": "Clinical analysis of 532nm frequency-doubled laser in treating retinal holes of 78 eyes",
        "abstract": "AIM: To evaluate the clinical effect of photocoagulation with 532nm frequency-doubled laser in patients with retinal hole. METHODS: Seventy-two cases (78 eyes) with retinal holes were treated with 532nm frequency-doubled laser. All the eyes were divided according to the quadrants of location of retinal holes and the size of retinal hole and existence of local retinal detachment accompanying retinal holes. Statistical analysis was made on these data. RESULTS: 1) The retinal holes were located in the upper quadrants of retina in 44 eyes and there were also retinal holes located in the lower quadrants of retina in 31 eyes (there were 3 eyes with retinal holes both located in the upper and lower quadrants of retina, which were not included in control group). The difference of photocoagulation effect between the two groups was statistically significant. 2) The retinal holes diameter \u22642 papilla diameter (PD) were present in 37 eyes, the holes diameter of retina >2PD were seen in 41 eyes, the difference of photocoagulation effect between the two groups was statistically significant. 3) Retinal holes without local retinal detachment were observed in 45 eyes, retinal holes with local retinal detachment were seen in 33 eyes, the difference of photocoagulation effect between the two groups was statistically significant. CONCLUSION:Photocoagulation with 532nm frequency-doubled laser is effective and safe to treat retinal holes. The effect is better in patients with retinal holes in the upper quadrants and with the retinal holes diameter \u22642PD and without local retinal detachment.",
        "keywords": [
            "photocoagulation",
            "532nm laser",
            "retinal hole"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": "Department of Ophthalmology"
            },
            {
                "name": "Xue Mi",
                "org": "Department of Digestive Endoscopy Center, the Central Hospital of Suining, Suining , Sichuan Province, China"
            }
        ],
        "venue": "International Eye Science",
        "year": 2013
    },
    "5O9TYTg3": {
        "id": "5O9TYTg3",
        "title": "Clinical observation of an improved suture method of scleral flap in trabeculectomy of acute angle-closure glaucoma",
        "abstract": "AIM:To evaluate the clinical effect of an improved suture method of scleral flap in trabeculectomy of acute angle-closure glaucoma.\u00b7METHODS: Twenty-eight eyes(16 cases) with acute angle-closure glaucoma underwent trabeculectomy and peripheral iridectomy.An improved suture method of scleral flap was adopted during operation.\u00b7RESULTS: All cases were followed-up for 6-12 months,averaging 8.7 months.The suture was pulled out during 3-17 days after operation,average 8.33 days. The intrao-cular tension was 12.23-18.86mmHg average 15.25mmHg before the suture being pulled out,and was 10.00-17.30mmHg ,average 11.96mmHg(P<0.05) after that.There were no complications and effusion of filter-bubble in all cases.The rate of shallow anterior chamber was 7% in 28 eyes(\u2160 grade :1 case ;\u2161 grade :1 case). At last,the intraocular tension in 28 eyes is from 10.00-17.30mmHg,averaging 12.55mmHg.The eyes of applanation filter-bubble,microcystic filter-bubble,and functional filter-bubble was 20,8,and 28 respectively.\u00b7CONCLUSION: Improved suture method of scleral flap in trabeculectomy of acute angle-closure glaucoma is safe and valid ,and in favor of intraocular tension controlling and functional filter-bubble forming in the long term.",
        "keywords": [
            "trabeculectomy",
            "acute angle-closure glaucoma",
            "improved suture method"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": "Department of Ophthalmology"
            },
            {
                "name": "Zhi-Jin Tang",
                "org": "Department of Ophthalmology"
            },
            {
                "name": "Xue Mi",
                "org": "Department of Otorhinolaryngology,Central Hospital of Suining City,Suining ,Sichuan Province,China"
            }
        ],
        "venue": "International Journal of Ophthalmology",
        "year": 2009
    },
    "CupgrzXn": {
        "id": "CupgrzXn",
        "title": "Clinical analysis of 532 nm frequency-doubled laser in treating retinal holes of 78 eyes",
        "abstract": "AIM: To evaluate the clinical effect of photocoagulation with 532 nm frequency-doubled laser in patients with retinal hole. METHODS: Seventy-two cases (78 eyes) with retinal holes were treated with 532 nm frequency-doubled laser. All the eyes were divided according to the quadrants of location of retinal holes and the size of retinal hole and existence of local retinal detachment accompanying retinal holes. Statistical analysis was made on these data. RESULTS: 1) The retinal holes were located in the upper quadrants of retina in 44 eyes and there were also retinal holes located in the lower quadrants of retina in 31 eyes (there were 3 eyes with retinal holes both located in the upper and lower quadrants of retina, which were not included in control group). The difference of photocoagulation effect between the two groups was statistically significant. 2) The retinal holes diameter \u22642 papilla diameter (PD) were present in 37 eyes, the holes diameter of retina >2PD were seen in 41 eyes, the difference of photocoagulation effect between the two groups was statistically significant. 3) Retinal holes without local retinal detachment were observed in 45 eyes, retinal holes with local retinal detachment were seen in 33 eyes, the difference of photocoagulation effect between the two groups was statistically significant. CONCLUSION: Photocoagulation with 532 nm frequency-doubled laser is effective and safe to treat retinal holes. The effect is better in patients with retinal holes in the upper quadrants and with the retinal holes diameter \u22642PD and without local retinal detachment.",
        "keywords": [
            "532 nm laser",
            "Photocoagulation",
            "Retinal hole"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": "Central Hospital of Suining(Suining Central Hospital of Sichuan Province,The Central Hospital of Suining,Central Hospital of Suining),,China"
            },
            {
                "name": "Xue Mi",
                "org": "Central Hospital of Suining(Suining Central Hospital of Sichuan Province,The Central Hospital of Suining,Central Hospital of Suining),,China"
            }
        ],
        "venue": "International Eye Science",
        "year": 2013
    },
    "iFeg5hK4": {
        "id": "iFeg5hK4",
        "title": "Clinical analysis of 49 cases with extraction eyeball by ocular trauma",
        "abstract": "AIM: To analyze the correlative factors of extraction eyeball by ocular trauma. METHODS: The data of cases with extraction eyeball by ocular trauma from July 2005 to July 2009 were collected,and the factors of trauma time,causation,age and occupation were analyzed. RESULTS: The shortest time from being injured to extraction eyeball was 1 hour, the longest time was 40 years,average 4.9 years. The main disease causing extraction eyeball was ocular rupture, secondary glaucoma the second and suppurative endoophthalmia the third. The primary causation causing extraction eyeball was complications from operation of cataract and glaucoma, wood or stone wound was the second. Occupational composition: agriculture and construction industry were the easiest to cause extraction eyeball, individual labour and factory worker were the second. The age of extraction eyeball was chiefly from 41 years to 60 years, followed by from 21 years to 40 years. CONCLUSION: The cases of ocular trauma should be treated in time and correctly,the especial population should receive skill training about how to protect eyes,the oculist from primary hospital should be reinforced the clinical skill training.",
        "keywords": [
            "ocular trauma",
            "extraction eyeball",
            "clinical analysis"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": "Department of Ophthalmology"
            },
            {
                "name": "Xue Mi",
                "org": "Department of Otorhinolaryngology, the Central Hospital of Suining, Suining , Sichuan Province,China"
            }
        ],
        "venue": "International Journal of Ophthalmology",
        "year": 2010
    },
    "L6jhK52Q": {
        "id": "L6jhK52Q",
        "title": "Cliniclal analysis of vitrectomy for vitreous hemorrhages in 21 cases",
        "abstract": "AIM:To analyze the clinical efffect of vitrectomy for vitreous hemorrhages.METHODS:Twenty-one cases(21 eyes)with vitreous hemorrhages underwent vitrectomy,their visual acuity was observed and the factors causing vitreous hemorrhages were analyzed.RESULTS:Of all the 21 cases,best-corrected visual acuity at last follow-up was:counting fingers-0.05 in 4 cases,\u22650.05-0.3 in 12 cases,\u22650.3 in 5 cases,off-blindness rate(visual acuity\u22650.05)was 81%,off-disability rate(visual acuity\u22650.3)was 24%.The first three leading causes of vitreous hemorrhage were branch vein occlusion,retinal breaks without detachment and diabetic retinopathy,accounting for 76% in all.CONCLUSION:Vitrectomy for vitreous hemorrhage is a safe and effective method,most patients can significantly improve their visual acuity after operation.\ue624",
        "keywords": [
            "vitrectomy",
            "clinical analysis",
            "vitreous hemorrhage"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": "Department of Ophthalmology,Central Hospital of Suining,Suining ,Sichuan Province,China"
            }
        ],
        "venue": "International Journal of Ophthalmology",
        "year": 2011
    },
    "hzPDGBP1": {
        "id": "hzPDGBP1",
        "title": "Clinical observation of different sewing method of scleral flap in trabeculectomy of acute angle-closure glaucoma",
        "abstract": "AIM:To compare the clinical effect of improved sewing method and traditional sewing method of scleral flap in trabeculectomy for acute angle-closure glaucoma.METHODS:Forty-two eyes 68 cases with acute angle-closure glaucoma underwent trabeculectomy and peripheral iridectomy,A group 16 cases 28 eyes:improved sewing method of scleral flap was adopted during operation;B group 26 cases 40 eyes:traditional sewing method of scleral flap was used during operation.RESULTS:All cases were followed-up for 6-12 months,averaged 6.7 months.A group:the suture was pulled out 3-17 days after operation,averaged 8.33 days.The shallow anterior chamber was 2 cases(7%) in A group and 12 cases(30%) in B group,there was significant difference between 2 groups(P<0.05).The intraocular tension was 10-19mmHg (averaged 13.31mmHg) in A and 6-42mmHg (averaged 14.64mmHg) in B after 2 weeks,there was no significant difference between 2 groups.The intrao-cular tension was 10-17.30mmHg (averaged 11.96mmHg) in A and 7-44mmHg(averaged 15.17mmHg) in B after 6 months,there was no significant difference between 2 groups.The functional filterbubble was 28 cases(100%) in A and 36 cases(90%) in B,there was no significant difference between 2 groups.CONCLUSION:It is safe and effetive that the improved sewing method of scleral flap for trabeculectomy of acute angle-closure glaucoma,and it is a better method to avoid the occurrance of shallow anterior chamber than the traditional sewing method in the forepart after operation.",
        "keywords": [
            "glaucoma",
            "sewing",
            "trabeculectomy",
            "scleral flap"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": "1Department of Ophthalmology"
            },
            {
                "name": "Xue Mi",
                "org": "2Department of ENT,the Central Hospital of Suining,Suining ,Sichuan Province,China"
            }
        ],
        "venue": "International Journal of Ophthalmology",
        "year": 2010
    },
    "c8ngM97e": {
        "id": "c8ngM97e",
        "title": "Application of iodized oil visualization in the therapy of chronic dacrocystitis",
        "abstract": "AIM:To study the application of iodized oil visualization in the therapy of chronic dacrocystitis. \u00b7METHODS:Fifty-two cases(58 eyes) with chronic dacrocystitis underwent iodized oil visualization.The form of dacryocyst was observed,and different therapy methods were selected according to it.The cases whose dacryocyst was more than 5.0mm\u00d73.0mm\u00d73.0mm received dacryorhinocy stotomy,the others\u2019 less than that received the YAG laser probing of lacrimal passage. \u00b7RESULTS:Nasolacrimal duct obstruction were in 53 eyes(91%) among which 45 eyes obstruction(85%) were at the starting position of nasolacrimal duct;4 eyes(8%) at the middle piece;4 eyes(8%) at the end-piece,and incomplete nasolacrimal duct obstruction occurred in 5 eyes(9%) . The form and size of dacryocyst in patients with chronic dacryocystitis:32 eyes(55%) showed cystoid distention;12 eyes(21%) anomalo-tubercle;5 eyes(9%) trabs;5 eyes(9%) sublobe;4 eyes(7%) segment dis-tention. 44 eyes of 46 patients who received dacryorhi-nocy stotomy were cured,and the recovery rate was 96%. 10 eyes of 12 patients who receiv-ed the laser prob-ing of lacrimal passage were cured,and the recovery rate was 83%.\u00b7CONCLUSION:The iodized oil visualization can guide us to choose a therapy method for dacrocystitis,and it should be a routine pretherapeutic examination of chronic dacrocystitis.",
        "keywords": [
            "application",
            "chronic dacrocys-titis",
            "iodized oil visualization"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": "Department of Ophthalmology,the Central Hospital of Suining,Suining ,Sichuan Province,China"
            },
            {
                "name": "Zhi-Jin Tang",
                "org": "Department of Ophthalmology,the Central Hospital of Suining,Suining ,Sichuan Province,China"
            },
            {
                "name": "Xue Mi",
                "org": "Department of Otorhino-laryngology,the Central Hospital of Suining,Suining ,Sichuan Province,China"
            }
        ],
        "venue": "International Journal of Ophthalmology",
        "year": 2009
    },
    "uDjrl41k": {
        "id": "uDjrl41k",
        "title": "Ethnobotanical Study on Ottelia acuminata,an Aquatic Edible Plant Occurring in Yunnan",
        "abstract": "The distribution,origins of names and its edible and medicinal values of Ottelia acuminata(Gagnep.) Dandy (Hydrocharitaceae) are introduced in the paper.The ethnobotanical investigations revealed that Ottelia acuminata is an ornamental,medicinal and tasty edible plant as well.The propagating and cultivating methods which follow the indigenous cultivation knowledge developed by the local people and some experiments are also proposed.It is suggested that the artificial cultivation of Ottelia acuminata is essential so as to meet the demands of market consumption and traditional eating culture in Yunnan.",
        "keywords": [
            "protection",
            "Ottelia acuminata(Gagnep.) Dandy",
            "cultivation",
            "ethnobotany"
        ],
        "authors": [
            {
                "name": "JIANG Zhu-tan",
                "org": "Kunming Institute of Botany,Chinese Academy of Sciences,Kunming ,China;Office of Wild Fauna and Flora Protection,Yunnan Department of Forestry,Kunming ,China"
            },
            {
                "name": "LI Heng",
                "org": "Kunming Institute of Botany,Chinese Academy of Sciences,Kunming ,China"
            },
            {
                "name": "DAO Zhi-ling",
                "org": "Kunming Institute of Botany,Chinese Academy of Sciences,Kunming ,China"
            },
            {
                "name": "LONG Chun-lin",
                "org": "Kunming Institute of Botany,Chinese Academy of Sciences,Kunming ,China;College of Life and Environmental Sciences,Minzu University of China,Beijing ,China"
            }
        ],
        "venue": "Journal of Inner Mongolia Normal University(Natural Science Edition)",
        "year": 2010
    },
    "qyh46ML8": {
        "id": "qyh46ML8",
        "title": "Biological Characteristics and Propagation Method of Sagina japonica in Dashanbao",
        "abstract": "Sagina japonica in Dashanbao National Nature Reserve was investigated and studied,the morphological characteristics was observed,the ecological and biological characteristics were studied,and its utilization value and propagation method were described as well.",
        "keywords": [
            "propagation method",
            "biological characteristics",
            "Sagina japonica"
        ],
        "authors": [
            {
                "name": "Zhong Xing-yao",
                "org": "Management Bureau of Dashanbao Grus nigricollis National Nature Reserve in Yunnan Province,Zhaotong Yunnan ,P.R.China"
            },
            {
                "name": "LI Heng",
                "org": "Kunming Institute of Botany,The Chinese Academy of Sciences,Kunming Yunnan ,P.R.China"
            }
        ],
        "venue": "Yunnan Forestry Science and Technology",
        "year": 2005
    },
    "Oqh6rvvE": {
        "id": "Oqh6rvvE",
        "title": "Botanical Verification of Divine Trees in \u201cLegend of Mountains and Rivers\u201d",
        "abstract": "There is a tale in the Chinese ancient book\"Legend of Mountains and Rivers\"where the sun rises from a \"Fusang Tree\"in the east,hangs above a\"Jian Tree\"at noon,and goes down at the\"Ruo Tree\"in the west. People have debated the reality of such Divine Trees for many centuries and arguments for and against their existence did not stop until Bronze Trees were discovered in Sanxingdui,Guanghan Prefecture,Sichuan Province. This archaeological discovery proved that Divine Trees referred to in folklore existed. Here we report verification of prototypes of the three Divine Trees referred to in\"Legend of Mountains and Rivers\",based on botanical knowledge and reference to the ancient literature. We verified that the Fusang Treeg Tprototype may have been Betula platyphylla,the Jian Tree' s prototype was possibly Cunninghamia lanceolata,while the Ruo Tree's prototype may have been Bombax ceiba.",
        "keywords": [
            "Legend of Mountains and Rivers",
            "Verification",
            "Betula platyphylla",
            "Cunninghamia lanceolata",
            "Divine Tree",
            "Bombax ceiba"
        ],
        "authors": [
            {
                "name": "LIU Ben-Xi",
                "org": " Yunnan Medicinal Institute of Yi Minority,Chuxiong ,China; China-Korea Biological Material Research Center,Yunnan Academy of Agricultural Sciences,Kunming ,China"
            },
            {
                "name": "LI Heng",
                "org": " Kunming Institute of Botany,Chinese Academy of Sciences, Kunming ,China"
            },
            {
                "name": "LONG Chun-Lin",
                "org": " Kunming Institute of Botany,Chinese Academy of Sciences, Kunming ,China; College of Life and Environmental Sciences,Minzu University of China,Beijing ,China"
            },
            {
                "name": "PEI Sheng-Ji",
                "org": " Kunming Institute of Botany,Chinese Academy of Sciences, Kunming ,China"
            },
            {
                "name": "LI Xiao-Ming",
                "org": " China-Korea Biological Material Research Center,Yunnan Academy of Agricultural Sciences,Kunming ,China; Yunnan Astronomical Observatory,Chinese Academy of Sciences,Kunming ,China"
            }
        ],
        "venue": "Plant Diversity and Resources",
        "year": 2013
    },
    "gdnp3ZKa": {
        "id": "gdnp3ZKa",
        "title": "Diterpenoids Chemodiversity of the Genus Isodon Spach from Lamiaceae",
        "abstract": "The species of the genus Isodon from Lamiaceae are often rich in diterpenoids with high medicinal value. According to its frame and oxidation level, the chemodiversity of diterpenoid compounds in genus Isodon was investigated in present study. UPGMA analysis showed that Isodon can be divided into two groups: one is the species producing diterpenoids with two or three ring skeletons, the other is producing diterpenoids with four ring skeleton. When the compounds were mapped on the molecular phylogenetic tree, we found that the species producing three cyclic diterpenoids are much older, such as I.lophanthoides and I.lophanthoides var. micranthus, while those producing four cyclic diterpenoids are younger, such as I.adenanthus and I.xerophilus. These results will contribute to finding and exploiting the active ingredients of dierpenoids from the genus Isodon.",
        "keywords": [
            "Phylogeny",
            "Isodon",
            "Diterpenoids",
            "Chemodiversity"
        ],
        "authors": [
            {
                "name": "LI Heng",
                "org": " Laboratory of Plant Phylogenetics and Conservation, Xishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences, Kunming , China; University of Chinese Academy of Sciences, Beijiing , China"
            },
            {
                "name": "PU Jian-Xin",
                "org": " State Key Laboratory of Phytochemistry and Plant Resource in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming , China"
            },
            {
                "name": "LI Jie",
                "org": " Laboratory of Plant Phylogenetics and Conservation, Xishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences, Kunming , China"
            }
        ],
        "venue": "Plant Diversity and Resources",
        "year": 2013
    },
    "UDISBgCt": {
        "id": "UDISBgCt",
        "title": "Primarily Verification of Plants in Manshu Book",
        "abstract": "The Manshu Book is historical monograph of Nanzhao(Yunnan)in Tang Dynasty.It recorded politics,economy,nationality and products of Nanzhao with ten volumes.The plants recorded in the Manshu Book were verified through comprehensive approaches including literature survey,comparative study,ethnobotany,along with biological characteristics and geographical distribution,and utilization of plants.",
        "keywords": [
            "Nanzhao(Yunnan)",
            "verification",
            "plants",
            "Manshu Book"
        ],
        "authors": [
            {
                "name": "LIU Ben-xi",
                "org": "Yunnan Medicinal Institute of Yi Minority,Chuxiong,Yunnan ,China"
            },
            {
                "name": "DONG Guang-ping",
                "org": "Yunnan Medicinal Institute of Yi Minority,Chuxiong,Yunnan ,China"
            },
            {
                "name": "YANG Ben-lei",
                "org": "Yunnan Medicinal Institute of Yi Minority,Chuxiong,Yunnan ,China"
            },
            {
                "name": "LI Heng",
                "org": "Kunming Institute of Botany,Chinese Academy of Sciences,Kunming Yunnan ,China"
            },
            {
                "name": "LONG Chun-lin",
                "org": "Kunming Institute of Botany,Chinese Academy of Sciences,Kunming Yunnan ,China;College of Life and Environmental Sciences,Minzu University of China,Beijing ,China"
            }
        ],
        "venue": "Journal of Yunnan University of Traditional Chinese Medicine",
        "year": 2013
    },
    "GVOEemE7": {
        "id": "GVOEemE7",
        "title": "A Floristic Study on the Seed Plants of the Northern Gaoligong Mountains in Western Yunnan, China",
        "abstract": "The northern Gaoligong Mountains is rich in species and it is one of the richest areas of plant diversity in the world. So far, 2 514 native species and 302 varieties (or subspecies) belonging to 778 genera in 172 families were recorded. Based on the statistics and analysis of families, genera, and species, a floristic study on the seed plants of the northern Gaoligong Mountains was carried out. The results are as follows: 1) The main floristic feature is temperate, but it is greatly influenced by tropical elements. The floristic relationships are complex, and many kinds of distribution types are represented here; 2) During the long geological history, the process of fusion and development among Gondwanaland and Laurasia floras is a key to the origin of modern flora of the northern Gaoligong Mountains. In addition, some elements that came from Indo-Malaysia and North Temperate (especial Eastern Asia) differentiated into variously rich endemic taxa in the region. Based on the tropical Asian flora, all of the endemic taxa and the two elements mentioned above together changed into the framework of the present flora during geological time; 3) The horizontal and vertical vicariance of the flora is evident in the northern Gaoligong Mountains.The disjunct distribution is also evident,the main disjunct type is a distribution pattern from northwest to southeast Yunnan or only distribution in the southwest of the line that along from northwest to southeast Yunnan; 4) The endemism within the flora is rich and the endemic elements differentiated strongly in the region.The palaeoendemic and neoendemic elements can co-exist in the region,but the neoendemic elements are dominant.These data show that northern Gaoligong Mountains not only is a refuge for some ancient floristic elements but also is a differentiation center for some new floristic elements.",
        "keywords": [
            "The northern Gaoligong Mountains",
            "Seed plants",
            "Phytogeography",
            "Flora"
        ],
        "authors": [
            {
                "name": "LI Rong",
                "org": "Kunming Institute of Botany, Chinese Academy of Sciences, Kunming , China"
            },
            {
                "name": "DAO Zhi-Ling",
                "org": "Kunming Institute of Botany, Chinese Academy of Sciences, Kunming , China"
            },
            {
                "name": "JI Yun-Heng",
                "org": "Kunming Institute of Botany, Chinese Academy of Sciences, Kunming , China"
            },
            {
                "name": "LI Heng",
                "org": "Kunming Institute of Botany, Chinese Academy of Sciences, Kunming , China"
            }
        ],
        "venue": "Acta Botanica Yunnanica",
        "year": 2007
    },
    "4mJJDdWB": {
        "id": "4mJJDdWB",
        "title": "Four Newly Recorded Species of Orchidaceae from Yunnan,China",
        "abstract": "Cheirostylis thailandica,Listera brevicaulis,Pholidota recurva and Sunipia annamensis are recorded for the first time in China.Cheirostylis thailandica is characterized by its petals with recurved tips and non-adnate to dorsal sepal,two green spots at the base of epichile,non-fringed lobules and stylids slightly longer than rostellum arms.Listera brevicaulis differs from all its allies by having very short stem with its leaves prostrate on the ground,bilobed lip with its lobelets recurved and meeting underneath.Pholidota recurva is characterized by its cylindrical and superposed internodes,secund flowers and emarginated-tipped lip.Sunipia annamensis is easily distinguished from its relatives by its inflorescence much longer than leaves and fleshy,broadly cordate lip with upcurved edges.",
        "keywords": [
            "New records",
            "Listera brevicaulis",
            "Cheirostylis thailandica",
            "Sunipia annamensis",
            "Orchidaceae",
            "Pholidota recurva",
            "China"
        ],
        "authors": [
            {
                "name": "JIN Xiao-Hua",
                "org": " Institute of Botany,Chinese Academy of Sciences,Beijing ,China"
            },
            {
                "name": "LI Heng",
                "org": " Kunming Institute of Botany,Chinese Academy of Sciences,Kunming ,China"
            },
            {
                "name": "LI De-Zhu",
                "org": " Kunming Institute of Botany,Chinese Academy of Sciences,Kunming ,China"
            }
        ],
        "venue": "Acta Botanica Yunnanica",
        "year": 2007
    },
    "lzbZ3mpQ": {
        "id": "lzbZ3mpQ",
        "title": "Typhonium baoshanense Z. L. Dao & H. Li, a new species of Araceae from western Yunnan,China",
        "abstract": "Typhonium baoshanense Z. L. Dao & H. Li (Araceae: Areae), a new species from western Yunnan, China, is described and illustrated. This species differs mainly from other species of Typhonium by the presence of one to two rings of sterile male flowers above the fertile male flowers, and from T. blumei Nicolson & Sivadasan by a conic female part of the spadix, the appendix not being truncate at its base, and by the angustate limb of the spathe. The chromosome number of Typhonium blumei, which occurs in same area, is 2n=52, while the chromosome number of the new species is 2n=10. The chromosome number of the new species is the lowest in the family Araceae.",
        "keywords": [
            "new species",
            "Araceae",
            "Typhonium",
            "Yunnan",
            "Typhonium baoshanense Z. L. Dao & H. Li",
            "China."
        ],
        "authors": [
            {
                "name": "DAO Zhi-Ling",
                "org": "Kunming Institute of Botany, the Chinese Academy of Sciences, Kunming , China"
            },
            {
                "name": "CHEN Shao-Tian",
                "org": "Kunming Institute of Botany, the Chinese Academy of Sciences, Kunming , China"
            },
            {
                "name": "JI Yun-Heng",
                "org": "Kunming Institute of Botany, the Chinese Academy of Sciences, Kunming , China"
            },
            {
                "name": "LI Heng",
                "org": "Kunming Institute of Botany, the Chinese Academy of Sciences, Kunming , China"
            }
        ],
        "venue": "Acta Phytotaxonomica Sinica",
        "year": 2007
    },
    "z3WTJleD": {
        "id": "z3WTJleD",
        "title": "Subalpine Flora of Dashanbao Black-necked Crane Natural Reserve,China",
        "abstract": "Based on the field investigation and specimen identification,the diversity of vascular plants in Dashanbao Black-necked Crane Natural Reserve is analyzed.The results show that the vascular plants in this region belong to 72 families,197 genera and 358 species(subspecies or varieties),in which 18 were cultivated and 3 were exotic invasive species.The floristic character is temperate feature and typical alpine flora of eastern Asia.The absence of trees or shrubs in current flora of Dashanbao Black-necked Crane Natural Reserve is a result of long time human activities.Relatively poor water plants in this region is nature adaptation.",
        "keywords": [
            "flora",
            "subalpine",
            "dashanbao",
            "introduced species",
            "nature reserves",
            "invasive species",
            "species diversity"
        ],
        "authors": [
            {
                "name": "LI Rong",
                "org": "Key Laboratory of Biodiversity and Biogeography,Kunming Institute of Botany,Chinese Academy of Sciences,Kunming ,China"
            },
            {
                "name": "LI Heng",
                "org": "Key Laboratory of Biodiversity and Biogeography,Kunming Institute of Botany,Chinese Academy of Sciences,Kunming ,China"
            }
        ],
        "venue": "Acta Botanica Boreali-Occidentalia Sinica",
        "year": 2010
    },
    "0kUbjIMW": {
        "id": "0kUbjIMW",
        "title": "Karyotypical Studies on an Endangered Species Alcimandra cathcartii (Magnoliaceae)",
        "abstract": "The karyotype of Alcimandra cathcartii Dandy is reported for the first time.Its karyotype can be formulated as 2n=2x=38=22m+15sm (3sat)+1st,belonging to Stebbins's 2A type.Only the eighteenth chromosome is st chromosome,and one satellite has been found on the fifth,sixth,and seventh chromosomes respectively.The interphase nucleus is characteristic of simple chromocenter type,and during mitotic prophase,the condensation behavior of chromosomes conforms to the interstitial type.Comparing with previous karyotype research results of Magnolia and Michelia,Alcimandra cathcartii is phylogenetically closed to Michelia but far from Magnolia.",
        "keywords": [
            "Alcimandra cathcartii",
            "Karyotype",
            "Phylogenetic relationships",
            "Magnoliaceae"
        ],
        "authors": [
            {
                "name": "ZHANG Xue-Mei",
                "org": " Kunming Institute of Botany,Chinese Academy of Sciences,Kunming ,China; Graduate University of Chinese Academy of Sciences,Beijing ,China"
            },
            {
                "name": "DAO Zhi-Ling",
                "org": " Kunming Institute of Botany,Chinese Academy of Sciences,Kunming ,China"
            },
            {
                "name": "LONG Chun-Lin",
                "org": " Kunming Institute of Botany,Chinese Academy of Sciences,Kunming ,China"
            },
            {
                "name": "LI Heng",
                "org": " Kunming Institute of Botany,Chinese Academy of Sciences,Kunming ,China"
            }
        ],
        "venue": "Acta Botanica Yunnanica",
        "year": 2006
    },
    "wgTC4CcF": {
        "id": "wgTC4CcF",
        "title": "A Comparative Floristic Study on the Seed Plants of the East Side and the West Side of the Northern Gaoligong Mts.in Northwestern Yunnan,China",
        "abstract": "The differences in rainfall and temperature between the east and west sides of the northern Gaoligong Mts.leads to distinct differences in the plant diversity and floristic characteristics between the two sides.Recorded taxa on the east side include 1 475 native species and 192 varieties(or subspecies) belonging to 580 genera in 152 families and for the west side include 1 804 native species and 186 varieties(or subspecies) belonging to 659 genera in 162 families.Based on the statistics and analysis of families,genera,and species,a comparative floristic study on the seed plants for the east side and the west side of the northern Gaoligong Mts.was carried out.The results are as follows:1) The present flora on the east and west sides of the northern Gaoligong Mts.have the same floristic origins,but the relative contribution from these different sources has changed through time.The result is that the floristic similarity of families,genera,and species between the east side and the west side has decreased through time;2) The floristic characteristic of seed plants for the west side has become more greatly influenced by tropical floristic elements than has that of the east side,and the influence by the temperate floristic elements has become less influenced on the west side but greater on the east side;3) The flora of the west side is more closely linked with that of the eastern Himalayans than is the flora of the east side,and the flora of the east side is more closely linked with the other floras farther to the east.Owing to the obstruct of the Gaoligong Mts.ridge itself,it is seemingly difficult for the species interchange between the two sides of the northern Gaoligong Mts.;4) The ecological-geographical environment has made it more conducive to species conservation and the speciation on the west side than on the east side,so the west side is not only a refuge for some ancient floristic elements but also as a cradle of some new species.",
        "keywords": [
            "The northern Gaoligong Mountains",
            "The west side",
            "Seed plants",
            "Flora",
            "Comparison",
            "The east side"
        ],
        "authors": [
            {
                "name": "LI Rong",
                "org": "Kunming Institute of Botany,Chinese Academy of Sciences,Kunming ,China"
            },
            {
                "name": "JI Yun-Heng",
                "org": "Kunming Institute of Botany,Chinese Academy of Sciences,Kunming ,China"
            },
            {
                "name": "DAO Zhi-Ling",
                "org": "Kunming Institute of Botany,Chinese Academy of Sciences,Kunming ,China"
            },
            {
                "name": "LI Heng",
                "org": "Kunming Institute of Botany,Chinese Academy of Sciences,Kunming ,China"
            }
        ],
        "venue": "Acta Botanica Yunnanica",
        "year": 2008
    },
    "cm1d57Le": {
        "id": "cm1d57Le",
        "title": "Eco-life Form of Plants from Dashanbao Black-necked Crane National Nature Reserve",
        "abstract": "Dashanbao Black-necked Crane National Nature Reserve is one of the international key wetlands located at northwest part of Zhaoyang district in Zhaotong city of Yunnan province,in which 358 species of vascular plants are recorded at present.In accordance with the eco-life form,28 species belong to aquatic plants,which accounts for 7.82 % of the total taxa;239 hydrophytes namely 66.76 % in total plants;91 terrestrial species,accounts for 25.14 % of the total species.Based on this study,four viewpoints were concluded as follows: \u2460The types of eco-system in Dashanbao nature reserve was relatively complete;\u2461Within the scope of northeastern Yunnan,the submerged plant communities of Batrachiium bungei,Blyxa echnisperma and Potamogeton oxyphyllus were firstly reported in Dashanbao;\u2462The rich and diverse hydrophyte perennial herbs(157 species) were the main plant resource in Dashanbao nature reserve;\u2463On the basis of the relic terrestrial evergreen shrub Quercus monimotricha and the shrubby bamboo Yushania qiaojiaensis,it is clear that subalpine shrub formation Quercus monimotricha and subalpine shrubby bamboo formation Yushania qiaojiaensis are original natural vegetation in Dashanbao natural reserve area.",
        "keywords": [
            "eco-life form",
            "nature reserve",
            "Dashanbao",
            "Black-necked Crane"
        ],
        "authors": [
            {
                "name": "LI Rong",
                "org": "Key Laboratory of Biodiversity and Biogeography,Kunming Institute of Botany,Chinese Academy of Sciences,Kunming Yunnan ,P.R.China"
            },
            {
                "name": "LI Heng",
                "org": "Key Laboratory of Biodiversity and Biogeography,Kunming Institute of Botany,Chinese Academy of Sciences,Kunming Yunnan ,P.R.China"
            }
        ],
        "venue": "Journal of West China Forestry Science",
        "year": 2012
    },
    "5HLZuQ0p": {
        "id": "5HLZuQ0p",
        "title": "Safety and effect of upper kindey calyces channel of percutaneous nephrolithotomy",
        "abstract": "Objective:To investigate the safety and effect of percutaneous nephrolithotomy via upper kindey calyces channel in the management of patients with renal calculi Method:Between June 2008 and May 2012,140 cases of patients with renal calculi were treated with percutaneous nephrolithotomy via upper calyce channel.Clinical data were analysed retrospectively and followed up for 3 to 36 months.Result:All 140 cases of patients with renal calculi were operated on successfully,the mean operating time was(42\u00b16) minutes,blood loss was(8.2\u00b12.5) g/L,the one-stage stone clear rate was 91.4%(128/140),the incidence of complication was 10.7%(15/140),failure of puncturation and loss of channel and severity blood loss were noted in 2 cases,injure of pleura 2 cases,perforation of pelvis or ureter 1 cases,blood loss after operation 2 cases,1 cases needed blood transfusion,febricity 6 cases,urinous infiltration 2 cases,neither loss of kidney nor death occurred in this group.The mean postoperative hospital stay was(7.5\u00b11.2) days.Conclusion:The present study demonstrated that in the treatment of renal calculi,percutaneous nephrolithotomy via upper calyce channel was safe and effective with the advantage of shorter operating time,less blood loss,high clear rate of stone,low incidence of complication,shorter hospital day.",
        "keywords": [
            "percutaneous nephrolithotomy",
            "renal calculi",
            "upper kindey calyces"
        ],
        "authors": [
            {
                "name": "LU Wei",
                "org": "Department of Urology,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,,China;Department of Urology,Xinyang Central Hospital"
            },
            {
                "name": "XIA Gang",
                "org": "Department of Urology,Xinyang Central Hospital"
            },
            {
                "name": "YIN Bo",
                "org": "Department of Urology,Xinyang Central Hospital"
            },
            {
                "name": "DIAO Changhui",
                "org": "Department of Urology,Xinyang Central Hospital"
            },
            {
                "name": "LI Heng",
                "org": "Department of Urology,Xinyang Central Hospital"
            },
            {
                "name": "ZHANG Daoyuan",
                "org": "Department of Urology,Xinyang Central Hospital"
            },
            {
                "name": "ZHOU Youqiang",
                "org": "Department of Urology,Xinyang Central Hospital"
            },
            {
                "name": "LI Hongbin",
                "org": "Department of Urology,Xinyang Central Hospital"
            },
            {
                "name": "ZHU Qijun",
                "org": "Department of Urology,Xinyang Central Hospital"
            },
            {
                "name": "BAN Dewen",
                "org": "Department of Urology,Xinyang Central Hospital"
            },
            {
                "name": "ZHANG Song",
                "org": "Department of Urology,Xinyang Central Hospital"
            }
        ],
        "venue": "Journal of Clinical Urology",
        "year": 2013
    },
    "wjNWIXeX": {
        "id": "wjNWIXeX",
        "title": "The clinical analysis of 20cases retroperitoneal laparoscopic ligation of lymphatic around renal pedicle for chyluria",
        "abstract": "Objective:To evaluate the surgical technique and clinical efficacy of retroperitoneal laparoscopic ligation of lymphatic around renal pedicle for chyluria.Method:Twenty cases of chyluria underwent retroperitoneal laparoscopic ligation of renal lymphatic vessels.Result:All cases have been successfully treated with retroperitoneoscopic management.The average operation time was 65(mean 45-90)minutes,the average blood loss was 30(mean 20-60)ml and the average hospital stay after operation was 8days.Chyluria disappeared in the 20unilateral cases.No recurrence of chyluria was found during the follow-up of 6month-2years.Conclusion:Retroperitoneal laparoscopic ligation of lymphatic around renal pedicle is an effective and efficient procedure and has the advantages of less blood loss,minimal invasion,complete lymphatic vessels ligation,short hospital stay and rapid recovery.So far,it is an ideal surgical procedure for treatment of chyluria.",
        "keywords": [
            "chyluria",
            "ligation of renal lymphatic vessels",
            "retroperitoneoscopy"
        ],
        "authors": [
            {
                "name": "LU Wei",
                "org": " Department of Urology,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,,China; Department of Urology,Xinyang Central Hospital"
            },
            {
                "name": "BAN Dewen",
                "org": " Department of Urology,Xinyang Central Hospital"
            },
            {
                "name": "DIAO Changhui",
                "org": " Department of Urology,Xinyang Central Hospital"
            },
            {
                "name": "XIA Gang",
                "org": " Department of Urology,Xinyang Central Hospital"
            },
            {
                "name": "YIN BO",
                "org": " Department of Urology,Xinyang Central Hospital"
            },
            {
                "name": "LI Heng",
                "org": " Department of Urology,Xinyang Central Hospital"
            },
            {
                "name": "ZHANG Daoyuan",
                "org": " Department of Urology,Xinyang Central Hospital"
            },
            {
                "name": "LI Hongbin",
                "org": " Department of Urology,Xinyang Central Hospital"
            },
            {
                "name": "ZHU Qijun",
                "org": " Department of Urology,Xinyang Central Hospital"
            },
            {
                "name": "LI Bin",
                "org": " Department of Urology,Xinyang Central Hospital"
            },
            {
                "name": "ZHANG Song",
                "org": " Department of Urology,Xinyang Central Hospital"
            }
        ],
        "venue": "Journal of Clinical Urology",
        "year": 2013
    },
    "EibaQ9x1": {
        "id": "EibaQ9x1",
        "title": "The Application of Chrysanthemum Shape Renal Stoma Catheter Stent to Treat Renal Abscess",
        "abstract": "Objective To observe the effect of chrysanthemum shape renal stoma catheter stent to treat renal abscess. Methods From the chrysanthemum shape renal stoma catheter stent ,use antibiotics to wash and drain the pelvis at the direction of pelvis,stent ,bladder,to remove obstruction.Results 28 cases had the renal functions recovered mostly or partly.Conclusion to control infection effectively, remove obstruction,reserve kidney ,decrease the removal rate of pyonephrosis and 2 nd term operation rate.",
        "keywords": [
            "renal stoma catheter",
            "wash stent",
            "Pyonephrosis",
            "drain."
        ],
        "authors": [
            {
                "name": "LI Hong-bin",
                "org": "Department of Urology, Xinyang Central Hospital, Henan, China"
            },
            {
                "name": "ZHOU You-qiang",
                "org": "Department of Urology, Xinyang Central Hospital, Henan, China"
            },
            {
                "name": "LI H",
                "org": "Department of Urology, Xinyang Central Hospital, Henan, China"
            }
        ],
        "venue": "China Healthcare Innovation",
        "year": 2007
    },
    "TT0J0ski": {
        "id": "TT0J0ski",
        "title": "Emergency Treatment of Upper Urinary Tract Obstruction Acute Renal Failure (report of 64 cases)",
        "abstract": "Objictive To improve the treatment of upper urinary tract obstruction acute renal failure.Methods To improve the recovery rate,recover the renal function with different methods according to the degree of acute renal failure.Results Satisfactory result has been obsreved in all,24Hurine output reached 2500-5000ml with BuN,and ScRdropped significantly.Normal renal fuction has been regained.Conclusion To improve recovery rate of acute renal failure, remove obstruction,recover the renal function is the key to treat acute renal failure.",
        "keywords": [
            "kidney failure",
            "treatment",
            "acute"
        ],
        "authors": [
            {
                "name": "LI Hong-bin",
                "org": "Department of Urology Xin Yang Central Hostital, Henan, , China"
            },
            {
                "name": "YIN Bo",
                "org": "Department of Urology Xin Yang Central Hostital, Henan, , China"
            },
            {
                "name": "LI Heng",
                "org": "Department of Urology Xin Yang Central Hostital, Henan, , China"
            }
        ],
        "venue": "China Healthcare Innovation",
        "year": 2007
    },
    "XsfYRw7q": {
        "id": "XsfYRw7q",
        "title": "Cystitis glandularis:report of 42 cases",
        "abstract": "Objective To present the features of cystitis glandularis and evaluate the diagnostic and treatment procedures for cystitis glandularis.Methods 42 cases of cystitis glandularis were surveyed,which were treated with transurethral resection or electrovaporization and bladder instillation of drug.Results 30 of 42 cases were cured with transurethral resection or electrovaporization and bladder instillation of drug.12 cases recurred 6\uff5e20 months after transurethral resection or electrovaporization.Six cases were treated with transurethral resection or electrovaporization,and three cases were undertaken with fract bladder resection,combined with ureter transplantation.One underwent total bladder resection.Two of the cases were found to be malignant,developed bladder adenocarcinoma,on pathological studies.Conclusions Cystoscope examination with pathologic studies is important in the early diagnosis of cystitis glandularis.Transurethral resection or electrovaporization combined bladder instillation of drug is the effective treatment.Cystitis glandularis may develop into adenocarcinoma,and close follow-up is therefore necessary.",
        "keywords": [
            "Diagnosis",
            "Cystitis",
            "Treatment"
        ],
        "authors": [
            {
                "name": "LU Wei",
                "org": "*Department of Urology,The Center Hospital of Xingyang,Xingyang,He'nan ,China"
            },
            {
                "name": "LI Heng",
                "org": "*Department of Urology,The Center Hospital of Xingyang,Xingyang,He'nan ,China"
            },
            {
                "name": "AO Bing",
                "org": "*Department of Urology,The Center Hospital of Xingyang,Xingyang,He'nan ,China"
            },
            {
                "name": "SU Li-hua",
                "org": "*Department of Urology,The Center Hospital of Xingyang,Xingyang,He'nan ,China"
            },
            {
                "name": "LI Hong-bin",
                "org": "*Department of Urology,The Center Hospital of Xingyang,Xingyang,He'nan ,China"
            },
            {
                "name": "ZHOU You-qiang",
                "org": "*Department of Urology,The Center Hospital of Xingyang,Xingyang,He'nan ,China"
            },
            {
                "name": "WU Kai-jun",
                "org": "*Department of Urology,The Center Hospital of Xingyang,Xingyang,He'nan ,China"
            }
        ],
        "venue": "Chinese Journal of Primary Medicine and Pharmacy",
        "year": 2006
    },
    "Pbb71zdx": {
        "id": "Pbb71zdx",
        "title": "Trans-ureteroscope Lithotripsy for impacted upper ureteric calculi after the selection of different cases of the calculi",
        "abstract": "Objective To probe to the means of selection of impacted upper ureteric calculi for Trans-ureteroscope Lithotripsy(TURL).Methods A total of 187 patients were diagnosed as impacted upper ureteric calculi and were selected according to the different cases of the calculi,after the selection 62 patients received Minimal Invasive Percutaneous Nephrolithotomy;125 patients received Trans-urethral Ureteroscope Lithotripsy,46 patients received auxiliary Extracorporeal Shock Wave Lithotripsy.The stone-free rate was recorded in 3 days and 1 month postoperation.Results In PCNL group,the stone-free rate was 95.2%(59/62) in 3 days postoperation,and it was 100%(62/62) in 1 month postoperation.In URL group,the stone-free rate was 36.8%(37/125) in 3 days postoperation,with the auxiliary ESWL,the stone-free rate was 98.4%(123/125) in 1 month postoperation.Conclusions High stone-free rate can be obtained with Minimal Invasive Percutaneous Nephrolithotomy for impacted upper ureteric calculi.The stone-free rate was less effective with Trans-urethral Ureteroscope Lithotripsy,but the result can be mostly raised with auxiliary ESWL after the selection of the different cases of the calculi.",
        "keywords": [
            "Ureteroscope",
            "Ureteric calculi",
            "Percutaneous nephrolithotomy"
        ],
        "authors": [
            {
                "name": "LI Heng",
                "org": ", et al.Department of Uroloy, Xinyang Central Hospital, Xinyang, China"
            },
            {
                "name": "LU Wei",
                "org": ", et al.Department of Uroloy, Xinyang Central Hospital, Xinyang, China"
            },
            {
                "name": "LI Hong-bin",
                "org": ", et al.Department of Uroloy, Xinyang Central Hospital, Xinyang, China"
            }
        ],
        "venue": "China Healthcare Frontiers",
        "year": 2009
    },
    "1dU8MlLp": {
        "id": "1dU8MlLp",
        "title": "Value of modified Allis technique in closed reduction of posteriorly dislocated hip with Pipkin I/II fracture]",
        "abstract": "To explore the value of modified Allis technique in closed reduction of posteriorly dislocated hip.For the control group, 98 cases of dislocated hips with Pipkin I/II fracture were studied retrospectively and their success reduction rates analyzed. For the experimental group, 36 cases with similar injury were studied prospectively. And the modified Allis technique was used and the success reduction rates were analyzed.Among the control group, 32 cases were reduced with a success rate of 67.3%. The success rate was 69.4% for the experimental group. And 97.2% of those unresponsive to the Allis technique were all successfully reduced by the modified Allis technique.The modified Allis technique is efficacious for posteriorly dislocated hips with Pipkin I/II fracture.",
        "keywords": [],
        "authors": [
            {
                "name": "Ma Lijie",
                "org": "Department of Orthopedic Trauma Center, Third Hospital, Hebei Medical University, Key Laboratory of Orthopedic Biomechanics of Hebei Province, Shijiazhuang 050051, China. Email: malijie126@126.com."
            },
            {
                "name": "Wu Haotian",
                "org": "Department of Orthopedic Trauma Center, Third Hospital, Hebei Medical University, Key Laboratory of Orthopedic Biomechanics of Hebei Province, Shijiazhuang 050051, China."
            },
            {
                "name": "Hou Zhiyong",
                "org": "Department of Orthopedic Trauma Center, Third Hospital, Hebei Medical University, Key Laboratory of Orthopedic Biomechanics of Hebei Province, Shijiazhuang 050051, China."
            },
            {
                "name": "Li Zengyan",
                "org": "Department of Orthopedic Trauma Center, Third Hospital, Hebei Medical University, Key Laboratory of Orthopedic Biomechanics of Hebei Province, Shijiazhuang 050051, China."
            },
            {
                "name": "Li Heng",
                "org": "Department of Orthopedic Trauma Center, Third Hospital, Hebei Medical University, Key Laboratory of Orthopedic Biomechanics of Hebei Province, Shijiazhuang 050051, China."
            }
        ],
        "venue": "Zhonghua yi xue za zhi",
        "year": 2014
    },
    "wNQBb4UY": {
        "id": "wNQBb4UY",
        "title": "Feasibility of one-stage open bone grafting in the treatment of infected bone defect in open fracture",
        "abstract": "Objective To investigate the feasibility of one-stage open bone grafting in the treatment of infected bone defect in open fracture.Methods The data of thirteen male patients(age range:17~51yr,average age:36yr)with infected bone defect caused by open fracture were retrospectively analyzed,which included 12 cases of tibial defect and 1 cases of femoral defect.The range of bone defect was 1.5 to 4 cm(average 2.5cm).The treatment procedure included dressing change,debridement and external fixation.After the debridement,the one stage open bone grafting was performed with autogenous bone chips,which was less than 5 mm in diameter.The dressing was changed regularly after operation,and antibiotics were given for an average of 21 days.Results The average follow-up period was 20 months.The wound was covered with granulation tissue for average 8 weeks and was closed for average 13 weeks after operation.All the bone defects were unioned after bone grafting(average 6 months)and no infection case recurred.Conclusion The one-stage open bone grafting is optional therapy for infected bone defect in open fracture.",
        "keywords": [
            "fractures",
            "external fixtor",
            "bone defect",
            "bone transplantation",
            "infection"
        ],
        "authors": [
            {
                "name": "LI Heng",
                "org": ",et al.Emergency Center for Orthopedics Trauma,The Third Hospital of Hebei Medical University,Shijiazhuang ,China"
            },
            {
                "name": "ZHANG Shiqiang",
                "org": ",et al.Emergency Center for Orthopedics Trauma,The Third Hospital of Hebei Medical University,Shijiazhuang ,China"
            },
            {
                "name": "HUO Jia",
                "org": ",et al.Emergency Center for Orthopedics Trauma,The Third Hospital of Hebei Medical University,Shijiazhuang ,China"
            }
        ],
        "venue": "Hebei Medical Journal",
        "year": 2009
    },
    "my3IxdMR": {
        "id": "my3IxdMR",
        "title": "TREATMENT OF FRACTURES OF PROXIMAL RADIUS WITH Ni-Ti SHAPE MEMORY ALLOY EMBRACING FIXATOR",
        "abstract": "Objective To find out an ideal method of internal fixation for the treatment of fractures of proximal radius. Methods From August 2001 to April 2004, 24 patients suffering from fractures of proximal radius were treated with Ni-Ti shape memory alloy embracing fixator. Of 24 patients, there were 19 males and 5 females, aging from 16 to 48 years; there were 9 cases of wrestling injury, 5 cases of crush injury, 4 cases of traffic accident injury, 3 cases of direct violence impact injury and 3 cases of high falling injury. All patients were given operation according to fix method of the shape memory alloy embracing fixator. All cases were regularly followed up to observe the fracture healing and functional recovery. Results All cases were followed up postoperatively from 4 months to 21 months with an average of 10 months. No complication occurred during operation and after operation. Healing by first intention was achieved. X-ray showed that all cases achieved clinical union 8-12 weeks after operation. According to Anderson's criteria and the results were excellent in 18 cases, good in 5 cases, and fair in 1 case. The excellent and good rate was 95.83 %. Conclusion [WTBZ]The internal fixation with shape memory alloy embracing fixator has as follows adventages: less trauma, esay-to-do, stable fixation, better tissue compatibility and less complication in treating fractures of proximal radius. This method can enhance the fracture healing and functional recovery. So it is a better method to treat fractures of proximal radius.",
        "keywords": [
            "Ni-Ti shape memory alloy embracing fixator Internal fixation Proximal radius fractures"
        ],
        "authors": [
            {
                "name": "ZHANG Shiqiang",
                "org": ", et al. Department of Orthopedics, the Third Hospital of Hebei Medical University, Shijiazhuang Hebei,,P.R.China"
            },
            {
                "name": "WANG Pengcheng",
                "org": ", et al. Department of Orthopedics, the Third Hospital of Hebei Medical University, Shijiazhuang Hebei,,P.R.China"
            },
            {
                "name": "LI Heng",
                "org": ", et al. Department of Orthopedics, the Third Hospital of Hebei Medical University, Shijiazhuang Hebei,,P.R.China"
            }
        ],
        "venue": "Chinese Journal of Reparative and Reconstructive Surgery",
        "year": 2006
    },
    "PnYTYzt6": {
        "id": "PnYTYzt6",
        "title": "Comparative study on the therapeutic effects between semi-ring distractor closed method and finger-guided open procedure combined with femoral intramedullary nailing on femoral shaft fracture",
        "abstract": "Objective To compare the therapeutic effect of semi-ring distractor closed method and finger-guided open procedure combined with femoral intramedullary nailing on femoral shaft fracture.Methods131 patients with femoral shaft fracture were randomly divided into two groups,68 patients in finger-guided group were treated by finger-guided method; the other 63 patients in distractor group were treatedby semi-ring distractor closed method. The number of surgical participant,operative time,quantity of blood transfusion,X-ray time during operation,complications,functional scores were recorded and compared in the two groups.ResultsInternal malrotation was significantly more common in distractor group with 17/63(27%) internally rotated by >10\u00b0,as compared with 5/68(6%) in finger-guided group(P<0.05).When the finger-guided method was used the average time was 116 min(65\uff5e170 min);the finger-guided was 136 min(110\uff5e192 min,P<0.05),The operation needed two operator at least in finger-guided group but three in distractor group. There were 11 patients each of whom received 400 ml blood in finger-guided group,but no blood transfusion in distractor group. X-ray was not needed in finger-guided group,however,the average time using image intensifier was 6 minutes (4\uff5e11min) in distractor group. There were 12 cases who had femoral shortening in finger-guide group,but only 2 cases in distractor group(P<0.01). The cases who had femoral shortening were all comminuted fractures. There was no significant difference between the two groups with regard to functional state of the patient duringone year.ConclusionThe finger-guided method is suitable for transverse fractures,however,distractor method is suitable for comminuted fractures.",
        "keywords": [
            "intramedullary nail",
            "fracture",
            "femoral",
            "distractor",
            "finger-guided"
        ],
        "authors": [
            {
                "name": "ZHANG Bofeng",
                "org": ",et al. Orthopaedic Trauma Emergent Center,The Third Hospital of Hebei Medical University,Hebei,Shijiazhuang "
            },
            {
                "name": "ZHANG Yingze",
                "org": ",et al. Orthopaedic Trauma Emergent Center,The Third Hospital of Hebei Medical University,Hebei,Shijiazhuang "
            },
            {
                "name": "QI Xiangbei",
                "org": ",et al. Orthopaedic Trauma Emergent Center,The Third Hospital of Hebei Medical University,Hebei,Shijiazhuang "
            },
            {
                "name": "LI H",
                "org": ",et al. Orthopaedic Trauma Emergent Center,The Third Hospital of Hebei Medical University,Hebei,Shijiazhuang "
            }
        ],
        "venue": "Hebei Medical Journal",
        "year": 2008
    },
    "EfEPRXos": {
        "id": "EfEPRXos",
        "title": "Treatment of fractures of proximal radius with Ni-Ti shape memory alloy embracing]",
        "abstract": "To find out an ideal method of internal fixation for the treatment of fractures of proximal radius.From August 2001 to April 2004, 24 patients suffering from fractures of proximal radius were treated with Ni-Ti shape memory alloy embracing fixator. Of 24 patients, there were 19 males and 5 females, aging from 16 to 48 years; there were 9 cases of wrestling injury, 5 cases of crush injury, 4 cases of traffic accident injury, 3 cases of direct violence impact injury and 3 cases of high falling injury. All patients were given operation according to fix method of the shape memory alloy embracing fixator. All cases were regularly followed up to observe the fracture healing and functional recovery.All cases were followed up postoperatively from 4 months to 21 months with an average of 10 months. No complication occurred during operation and after operation. Healing by first intention was achieved. X-ray showed that all cases achieved clinical union 8-12 weeks after operation. According to Anderson's criteria and the results were excellent in 18 cases, good in 5 cases, and fair in 1 case. The excellent and good rate was 95.83%.The internal fixation with shape memory alloy embracing fixator has as follows advantages: less trauma, esay-to-do, stable fixation, better tissue compatibility and less complication in treating fractures of proximal radius. This method can enhance the fracture healing and functional recovery. So it is a better method to treat fractures of proximal radius.",
        "keywords": [],
        "authors": [
            {
                "name": "Zhang Shiqiang",
                "org": "Department of Orthopedics, Third Hospital of Hebei Medical University, Shijiazhuang Hebei 050051, P R China. zhangstronger@yahoo.com.cn"
            },
            {
                "name": "Wang Pengcheng",
                "org": ""
            },
            {
                "name": "Li Heng",
                "org": ""
            },
            {
                "name": "Peng Aqin",
                "org": ""
            },
            {
                "name": "Zhao Changping",
                "org": ""
            },
            {
                "name": "Li Zhi",
                "org": ""
            }
        ],
        "venue": "Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery",
        "year": 2006
    },
    "RQgmZ7LJ": {
        "id": "RQgmZ7LJ",
        "title": "Clinical comparative study of minimally surgical treatment of cholecysto choledocholithiasis",
        "abstract": "Objective:To evaluate the effect of LC+LCBDE and ERCP combined LC on treating cholecysto-choledocholithiasis. Method:Fifty-two patients with calculus of extra hepatic bile duct were treated by LC+LCBDE,and thirty-eight cases by ERCP combined with LC.The clinical data of two groups was contrasted in the operation indication,time,cost,incidence rate of complication,operation effect and so on. Result:There have different operation indication. Conclusion:There are respective indication,advantages and disadvantages in the two groups.Different operation should be adopted according to specific condition.",
        "keywords": [
            "laparoscopic cholecystomy",
            "common bile duct stones",
            "laparoscopic common bile duct exploration",
            "endoscopic retrograde cholangio\ue011pancreatography"
        ],
        "authors": [
            {
                "name": "HUANG Dong",
                "org": "Department of General Surgery,Taihe Hospital,Hubei University of Medicine,Shiyan,Hubei,,China"
            },
            {
                "name": "SUN Min",
                "org": "Department of General Surgery,Taihe Hospital,Hubei University of Medicine,Shiyan,Hubei,,China"
            },
            {
                "name": "DAN Chao",
                "org": "Department of General Surgery,Taihe Hospital,Hubei University of Medicine,Shiyan,Hubei,,China"
            },
            {
                "name": "LI Heng",
                "org": "Department of General Surgery,Taihe Hospital,Hubei University of Medicine,Shiyan,Hubei,,China"
            }
        ],
        "venue": "Journal of Clinical Emergency",
        "year": 2013
    },
    "ZH8UHANQ": {
        "id": "ZH8UHANQ",
        "title": "Application of combined laparoscopic peritoneal exploration and tumor markers in diagnosis of unknown origin aseites",
        "abstract": "Objective:To assess the value of combined laparoscopic peritoneal exploration and tumor markers in diagnosing unknown origin ascites.Methods: Retrospective analysis of the etiological factor of 86 cases were identified by laparoscopic abdomimal exploration and biopsy from May 2006 to September 2011.Diagnose accordance rate of different routine examinations,tumor marker in ascites between tuberculous peritonitis and abdominal extensive metastatic carcinoma,the serum tumor markers concentrations of the first test and after 6 months treatment,were compared.Results: The etiological factor of 82 cases were identified by laparoscopic exploration and biopsy,there were 35 cases of tuberculous peritonitis and 30 cases of metastatic carcinoma.There was no difference in diagnosis rate among different routine conventional in aging examinations(P>0.05).There was no significant difference of ascitic CEA,CA199,CA242 concentrations between tuberculous peritonitis and abdominal extensive metastatic carcinoma(P> 0.05).The ascitic CA125 of abdominal extensive metastatic carcinoma was more than of tuberculous peritonitis(P<0.05).There was significant difference of serums marker CA125 between the patients with tuberculous peritonitis after 6 months treatment and their first serum test on admission(P<0.05).Conclusion: Combined laparoscopic peritoneal exploration and tumor markers in diagnosing unknown origin ascites was efficient.The ascitic CA125 of abdominal extensive metastatic carcinoma was more than of tuberculous peritonitis.Serum tumor marker CA125 can be used as performance monitor in the patients with tuberculous peritonitis and indicator of therapeutic effect.",
        "keywords": [
            "ascites",
            "tumor marker",
            "diagnosis",
            "laparoscopic exploration"
        ],
        "authors": [
            {
                "name": "Sun Min",
                "org": " Department of General Surgery,Taihe Hospital,Hubei University of Medicine,Hubei Shiyan ,China"
            },
            {
                "name": "Li Heng",
                "org": " Department of General Surgery,Taihe Hospital,Hubei University of Medicine,Hubei Shiyan ,China"
            },
            {
                "name": "Huang Dong",
                "org": " Department of General Surgery,Taihe Hospital,Hubei University of Medicine,Hubei Shiyan ,China"
            }
        ],
        "venue": "Journal of Modern Oncology",
        "year": 2013
    },
    "GI3Wvw2M": {
        "id": "GI3Wvw2M",
        "title": "Establishing Diagnostic Model of Serum Protein Fingerprinting Patterns for Hepatic Metastasis of Colorectal Carcinoma and its Clinical Application",
        "abstract": "Objective To find new biomarkers and to establish serum protein fingerprinting patterns for early detection and diagnosis of hepatic metastasis of colorectal carcinoma using SELDI-TOF-MS and bioinformatics tools.Methods The serum protein of 76 serum samples(including 8 cases of hepatic metastasis of colorectal carcinoma,58 cases of colorectal carcinoma without hepatic metastasis and 10 healthy individuals) was bound to CM10 chip and tested by surface-enhanced laser desorption/ionization time of flight mass spectrometry(SELDI-TOF-MS).The data of these serum protein profile were analyzed with Support Vector Machine(SVM) and discriminant analysis to establish and evaluate the diagnostic model.Results \u2474The diagnostic model for discriminating hepatic metastasis of colorectal carcinoma from healthy individuals was established with a sensitivity and specificity of 100%;\u2475The diagnostic model for discriminating hepatic metastasis of colorectal carcinoma from colorectal carcinoma without hepatic metastasis was established with a sensitivity of 87.5%,specificity of 98.28%;\u2476The diagnostic model for discriminating hepatic metastasis of colorectal carcinoma from control group was established with a sensitivity of 75.0% and specificity of 100% respectively.Conclusion The combination of SELDI with bioinformatics tools is a novel effective method for screening and identifying candidate biomarkers of hepatic metastasis of colorectal carcinoma and it may provide a new means of the early clinical diagnosis,prognosis and characterization of hepatic metastasis of colorectal carcinoma.",
        "keywords": [
            "SELDI-TOF-MS",
            "Colorectal cacinoma",
            "Hepatic metastasis",
            "Diagnostic model",
            "Serum proteomics",
            "Biomarker",
            "SVM"
        ],
        "authors": [
            {
                "name": "SUN Min",
                "org": "Department of General Surgery,Taihe Hospital,Hubei University of Medicine,Shiyan,Hubei ,China"
            },
            {
                "name": "HUANG Dong",
                "org": "Department of General Surgery,Taihe Hospital,Hubei University of Medicine,Shiyan,Hubei ,China"
            },
            {
                "name": "LI Heng",
                "org": "Department of General Surgery,Taihe Hospital,Hubei University of Medicine,Shiyan,Hubei ,China"
            },
            {
                "name": "XIONG Bin",
                "org": "Department of Oncology,Zhongnan Hospital,Wuhan University,Wuhan,Hubei ,China"
            }
        ],
        "venue": "Journal of Hubei University of Medicine",
        "year": 2012
    },
    "dR8ULclN": {
        "id": "dR8ULclN",
        "title": "Surgical Treatment for Obstructive Colorectal Carcinoma",
        "abstract": "Objective To review the experience on surgery for colorectal carcinoma presenting with acute intestinal obstruction.Methods A retrospective analysis was made on the clinical data,June.2006-June.2011,of 97 cases of colorectal carcinoma complicated with acute intestinal obstruction.Results Of the 76 patients operated,thirty primary resection and anastomosis were performed in thirty-two cases with right hemicolon,there was no leakage case.Of the other 34 cases,15 with left hemicolon received primary resection and anastomosis,27 Dixon operations,10 Miles operations,13 Hartmann operations,6 colostomy.Postoperative complications were infection of incisional wound(4 cases),pulmonary infection(2 cases).All patients with postoperative complications were cured.One died of multiple organ failure.Conclusion For colorectal cancer presenting with acute intestinal obstruction,timely proper operation should be done according to the specific features of the individual,primary resection and anastomosis is feasible and effective for left colorectal carcinoma with intdstinal obstruction in selected cases.Intensive perioperative care is the key in reducing postoperative complications and mortality.",
        "keywords": [
            "Operative",
            "Colorectal neoplasms",
            "Postoperative complications",
            "Surgical procedures",
            "Intestinal obstruction"
        ],
        "authors": [
            {
                "name": "Fu Yan",
                "org": "Department of General Surgery,Taihe Hosipital,Hubei Medical College.Shiyan ,China"
            },
            {
                "name": "Li Heng",
                "org": "Department of General Surgery,Taihe Hosipital,Hubei Medical College.Shiyan ,China"
            },
            {
                "name": "Huang Dong",
                "org": "Department of General Surgery,Taihe Hosipital,Hubei Medical College.Shiyan ,China"
            }
        ],
        "venue": "Journal of Colorectal & Anal Surgery",
        "year": 2012
    },
    "7OEI2CsW": {
        "id": "7OEI2CsW",
        "title": "Clinical application of lidocaine combined with gentamicin in the prevention of urinary retention after removal of the catheter after PPH",
        "abstract": "Objective To evaluate the clinical efficacy of lidocaine combined gentamicin in the prevention of urinary retention after removal of the catheter after procedure for prolapse and hemorrhoids (PPH). Methods Before removal of catheter, lidocaine combined with gentamicin were injected through the catheter into the bladder. The urinary retention after removal of the catheter was observed. Results All the 185 patients can urinate smoothly, achieving the effective rate of 100%. Conclusion For preventing urinary retention after removal of the catheter after PPH, lidocaine combined with gentamicin are quite effective and safe, with high success rate, simple operation, and no significant adverse reactions and complications.",
        "keywords": [
            "Gentamicin",
            "Urinary retention",
            "Procedure for prolapse and hemorrhoids (PPH)",
            "Lidocaine"
        ],
        "authors": [
            {
                "name": "DAN Chao",
                "org": " Department of General Surgery \u2163, Taihe Hospital Affiliated to Hubei Medical College, Shiyan , Hubei, CHINA"
            },
            {
                "name": "LI Heng",
                "org": " Department of General Surgery \u2163, Taihe Hospital Affiliated to Hubei Medical College, Shiyan , Hubei, CHINA"
            },
            {
                "name": "WANG Chuan-bin",
                "org": " Department of General Surgery \u2163, Taihe Hospital Affiliated to Hubei Medical College, Shiyan , Hubei, CHINA"
            },
            {
                "name": "HUANG Dong",
                "org": " Department of General Surgery \u2163, Taihe Hospital Affiliated to Hubei Medical College, Shiyan , Hubei, CHINA"
            },
            {
                "name": "LIU Quan",
                "org": " Department of General Surgery \u2163, Taihe Hospital Affiliated to Hubei Medical College, Shiyan , Hubei, CHINA"
            },
            {
                "name": "FU Yan",
                "org": " Department of General Surgery \u2163, Taihe Hospital Affiliated to Hubei Medical College, Shiyan , Hubei, CHINA"
            },
            {
                "name": "SUN Min",
                "org": " Department of General Surgery \u2163, Taihe Hospital Affiliated to Hubei Medical College, Shiyan , Hubei, CHINA"
            }
        ],
        "venue": "Hainan Medical Journal",
        "year": 2013
    },
    "G1oBMCxQ": {
        "id": "G1oBMCxQ",
        "title": "Structural Economic Growth,Structural Trade and Transferring of Rural Surplus Labor in China",
        "abstract": "The structural economic growth is the main power to promote the allocation efficiency of production factors,and this effect has been strengthened dynamically by trade structure.The transferring of rural surplus labor in China has been advanced by structural economic growth since reform,but its speed,structure,process,income and distribute doesn't accord with the process of structural economic growth,which indicates that the structural economic growth in China has excessively emphasized the comparative advantage of low-cost labor.To optimize the industrial structure and to promote the efficiency of structural economic growth should be the key for drawing industrial policy in the future.",
        "keywords": [
            "Structural Economic Growth",
            "Transferring of Rural Surplus Labor",
            "Structural Trade"
        ],
        "authors": [
            {
                "name": "LI Heng",
                "org": "Research Institute of Yellow River Civilization and Sustainable Development,Henan University,Kaifeng ,China"
            }
        ],
        "venue": "Journal of Huazhong University of Science and Technology(Social Science Edition)",
        "year": 2007
    },
    "OFZvRrAJ": {
        "id": "OFZvRrAJ",
        "title": "Study on Relation Between Foreign Trade and Income Gap Between Urban and Rural Areas:1985-2008",
        "abstract": "With the rapid growth of China's foreign trade since the opening-up and reform,the income gap between urban and rural areas presents gradual expanding tendency.By using the panel data of 30 provinces from 1985 to 2008,this paper studies on the effects mechanism of trade on the income gap.The research discoveries that the trade as an important factor promotes the income gap expanding.The effective way is related to not only the regional differences,but the nature of economic development in different regions.",
        "keywords": [
            "income gap between urban and rural areas",
            "foreign trade",
            "urbanization"
        ],
        "authors": [
            {
                "name": "LI Heng",
                "org": "Research Institute of Yellow River Civilization and Sustainable Development, Henan University,Kaifeng,Henan ,China"
            },
            {
                "name": "YUAN Dong-mei",
                "org": "Research Institute of Yellow River Civilization and Sustainable Development, Henan University,Kaifeng,Henan ,China"
            }
        ],
        "venue": "Journal of Changsha University of Science & Technology(Social Science)",
        "year": 2012
    },
    "EbIGgbpL": {
        "id": "EbIGgbpL",
        "title": "Boundary Penetrability,Enterprise Competence and the Governance of Industrial Clusters",
        "abstract": "This paper sets forth the logical governance of industrial clusters based on the competence of enterprise,and points out that creating boundless enterprise is indispensable to advance the competence of enterprise inter-clusters,and researches into the efficiency of two patterns of governance induced by the competence of boundless enterprise based on the modularization and the value chain.",
        "keywords": [
            "boundless enterprise",
            "governance of industrial clusters",
            "enterprise competence"
        ],
        "authors": [
            {
                "name": "LI Heng",
                "org": "Key Research Institute of Yellow River Civilization and Sustainable Development,Henan University,Kaifeng "
            }
        ],
        "venue": "Soft Science",
        "year": 2006
    },
    "SlfaPzDo": {
        "id": "SlfaPzDo",
        "title": "Spatial Characteristics of the Regional Innovational Ability and Effects on the Economic Growth",
        "abstract": "The regional disparities of knowledge and innovation distribution lead to the differences in income distribution and economic growth.Using spatial econometric methods,this paper studies the spatial distribution of the regional innovational ability in China,and the relationships between innovational ability and regional economic growth.The research findings:that the regional innovational ability has the spatial auto-correlation characteristics in every region of China.The regional innovational ability has the spatial spillovers effecting on the local and the neighboring regional economic growth.In the region with the higher level of the economic opening up and the urbanization,the spatial spillover effects of the regional innovational ability are stronger.",
        "keywords": [
            "regional innovational ability",
            "spatial econometric",
            "economic growth",
            "spatial spillover"
        ],
        "authors": [
            {
                "name": "LI Heng",
                "org": "Key Research Institute of Yellow River Civilization and Sustainable Development,Henan University,Kaifeng ,Henan,China"
            }
        ],
        "venue": "Journal of Henan University(Social Science)",
        "year": 2012
    },
    "QcoyWyWP": {
        "id": "QcoyWyWP",
        "title": "Organization Equity:Governance Structure of Networks Organization and Its Efficiency",
        "abstract": "The paper analyzes the relation between organization equity and organization efficiency,and points out the essence of organization equity is the governance structure of inter-firm networks based on Nash equilibrium, and then discusses its applicable value with the example of industrial clusters upgrade in China.",
        "keywords": [
            "efficiency of inter-firm networks",
            "organization equity",
            "industrial clusters"
        ],
        "authors": [
            {
                "name": "LI Heng",
                "org": "Key Research Institute of Yellow River CiviLization and Sustainable Development,Henan University,Kaifeng "
            }
        ],
        "venue": "Soft Science",
        "year": 2008
    },
    "PO61SLCN": {
        "id": "PO61SLCN",
        "title": "The Dynamic Mechanism and Development Pattern  on in China's Inland Provinces\u2014\u2014As an Example of Open Economy",
        "abstract": "The development in the inland provinces has made great progress since reform and opening-up,but many problems still exit in foreign investment attraction,the labor market growth and the industrializing process.The opening and development of the inland provinces face both the free flow of products in the international environment and that of factors in the national environment.Under such circumstances,the suitable pattern should be integrated resource mode with the emphasis on the free flow of productive factors,instead of the improvement trade export-led pattern in the east.It will not only promote the inland provinces to make full use of comparative advantages but also develop regional coordinated development with the eastern area.",
        "keywords": [
            "open economy",
            "inland provinces",
            "comparative advantages"
        ],
        "authors": [
            {
                "name": "LI Heng",
                "org": "Research Center of Yellow River Civilization and Sustainable Development,Henan University,Kaifeng ,China"
            }
        ],
        "venue": "Journal of Huazhong University of Science and Technology(Social Science Edition)",
        "year": 2011
    },
    "4DaB8tVN": {
        "id": "4DaB8tVN",
        "title": "On the Regional Disparities of China's Utilization of FDI and the Coordinated Development of Regional Economy",
        "abstract": "Since China\u2019s reform and opening-up,China\u2019s FDI has been growing at a rapid speed,and at the same time,the regional distribution of FDI is out of balance,which constitutes the main reason behind the disequilibrium of the development of China\u2019s regional economy.This paper analyzes the situation of FDI\u2019s regional discrepancy in our country,and further points out that government policy,regional costs,the degree of economic agglomeration and the degree of regional openness are the main reasons which contribute to the regional discrepancies of China\u2019s FDI development.The paper also elaborates on the effect of FDI on the discrepancies of regional economic development from three aspects: capital formation,export effect and the industrial structural changes.",
        "keywords": [
            "coordinated development of regional economy",
            "FDI",
            "regional disparities"
        ],
        "authors": [
            {
                "name": "XU Xia-lian",
                "org": "Research Institute of Yellow River Civilization and Sustainable Development,Henan University,Kaifeng,Henan ,China"
            },
            {
                "name": "LI Heng",
                "org": "Research Institute of Yellow River Civilization and Sustainable Development,Henan University,Kaifeng,Henan ,China"
            }
        ],
        "venue": "Journal of Nanyang Normal University",
        "year": 2009
    },
    "OiQaFy4O": {
        "id": "OiQaFy4O",
        "title": "Isotope Evidence of Material Sources of the Dabaoshan Polymetallic Deposit",
        "abstract": "According to S,Pb,H and O isotopic composition analyses of ores and gangue minerals in the Dabaoshan polymetallic deposit,the 206Pb/204Pb ratio varies from 17.930 to 21.480,207Pb/204Pb ratio from 15.491 to 16.215,and the 208Pb/204Pb ratio from 56.390 to 37.990,forming a good linear relationship.The \u03b434S value of pyrite in Devonian strata ranges from-22.5\u2030 to +17.9\u2030,whereas the \u03b434S value of the sulfide deposits from-2.4\u2030 to +4.6\u2030.The association of pyrite,sphalerite and galena is characterized by \u03b434Spy>\u03b434Ssp> \u03b434Sgn,and the \u03b434S\u03a3S(0\u00b13\u2030)is estimated from the sulfur isotopic composition of pyrrhotine.The hydrogen isotope value of sulfide inclusions varies from-101\u2030 to-123\u2030,and the oxygen isotope value of quartz associated with sulfide is +9.3\u2030 \uff5e +17.9\u2030.If it is converted into the oxygen isotope of water,the value ranges from +0.3\u2030 to +3.9\u2030,suggesting that the sources of the ore-forming hydrothermal fluids were rather complex.",
        "keywords": [
            "Dabaoshan",
            "isotopic",
            "Guangdong",
            "polymetallic deposit"
        ],
        "authors": [
            {
                "name": "XU Wenxin",
                "org": ")1)Guilin Research Institute of Geology for Mineral Resources,Guilin,Guangxi "
            },
            {
                "name": "LI Heng",
                "org": ")1)Guilin Research Institute of Geology for Mineral Resources,Guilin,Guangxi "
            },
            {
                "name": "CHEN Minyang",
                "org": ")1)Guilin Research Institute of Geology for Mineral Resources,Guilin,Guangxi "
            },
            {
                "name": "HUANG Dexin",
                "org": "Guangdong Nonferrous Netals Geo-exploration Buerau,Guangzhou,Guangdong "
            },
            {
                "name": "ZHANG Futie",
                "org": "Guangdong Nonferrous Netals Geo-exploration Buerau,Guangzhou,Guangdong "
            },
            {
                "name": "WANG Liming",
                "org": "Guangdong Nonferrous Netals Geo-exploration Buerau,Guangzhou,Guangdong "
            }
        ],
        "venue": "Acta Geoscientica Sinica",
        "year": 2008
    },
    "spGZlbgg": {
        "id": "spGZlbgg",
        "title": "Geochemical research on sulfur and lead isotope of Huoshibulake Pb-Zn deposit in Xinjiang",
        "abstract": "Determination on sulfur and lead isotope of Huoshibulake Pb-Zn deposit shows that in early stage of mineralization,\u03b434S of pyrite is in the range of-12.1\u2030 ~-8.5\u2030,\u03b434S of sphalerite is-17.6\u2030,\u03b434S of galenite is-18.8\u2030;in late stage,\u03b434S of pyrite is in the range of +12.8\u2030 ~ +22.2\u2030,\u03b434S of sphalerite is in the range of +20.0\u2030 ~ +24.2\u2030,\u03b434S of galenite is +14.4\u2030 ~ +22.2\u2030.Sulfur isotope value changes from large negative values to the large positive values while the mineralization time changes from early stage to late stage.In galenite,the ratio of 206Pb/204Pb,207Pb/204Pb and 208Pb/204Pb are 17.900~18.086,15.586~15.732 and 37.997~38.381 respectively;the ratio of 206Pb/204Pb,207Pb/204Pb and 208Pb/204Pb in pyrite are 17.950,15.633 and 38.144 respectively;the ratio of 206Pb/204Pb,207Pb/204Pb and 208Pb/204Pb in limestone are 18.156~18.875,15.396~ 15.855,37.631~38.967 respectively.Sulfur isotope indicates that the source of sulfur is reduced sulphur of seawater sulphate.Lead isotope compositions indicate that there are two sources at least.",
        "keywords": [
            "mineralization material source",
            "Pb-Zn deposit",
            "isotope"
        ],
        "authors": [
            {
                "name": "LI Heng",
                "org": "China Nonferrous Metal%%#Guilin%%#Geology and Mining Co.,Ltd.,Guilin ,Guangxi,China"
            },
            {
                "name": "XU Wen-xin",
                "org": "China Nonferrous Metal%%#Guilin%%#Geology and Mining Co.,Ltd.,Guilin ,Guangxi,China"
            },
            {
                "name": "DENG Gui-an",
                "org": "China Nonferrous Metal%%#Guilin%%#Geology and Mining Co.,Ltd.,Guilin ,Guangxi,China"
            }
        ],
        "venue": "Mineral Resources and Geology",
        "year": 2012
    },
    "dgJmaKWY": {
        "id": "dgJmaKWY",
        "title": "Research progress on heavy metal pollution prevention technology of leachate from Karst-type tailings pond",
        "abstract": "This paper makes a research on the related methods of heavy metal pollution prevention technology of leachate from karst-type tailings ponds.The results show that permeable reactive barrier(PRB) has several advantages in treating polluted groundwater.These advantages include low construction investment in early stage,flexibility of using suitable treating methods according to different contaminants,and no energy consumption in operating period;moreover,no land resources will be occupied by treatment facilities.It is one of the most promising methods in treating leachate from karst-type tailings ponds.",
        "keywords": [
            "progress",
            "heavy metal",
            "leachate",
            "pollution prevention technology",
            "tailings pond"
        ],
        "authors": [
            {
                "name": "XIAO Xiao-yu",
                "org": "China Nonferrous Metal%%#Guilin%%# Geology and Mining Co.,Ltd.,Guilin ,Guangxi,China;Technological Research Center of Guangxi Environment Treatment Engineering,Guilin ,Guangxi,China;Key Lab of Guangxi Environment Engineering and Protection Evaluation,Guilin ,Guangxi,China"
            },
            {
                "name": "LI Heng",
                "org": "China Nonferrous Metal%%#Guilin%%# Geology and Mining Co.,Ltd.,Guilin ,Guangxi,China;Technological Research Center of Guangxi Environment Treatment Engineering,Guilin ,Guangxi,China;Key Lab of Guangxi Environment Engineering and Protection Evaluation,Guilin ,Guangxi,China"
            },
            {
                "name": "ZHANG Jing",
                "org": "China Nonferrous Metal%%#Guilin%%# Geology and Mining Co.,Ltd.,Guilin ,Guangxi,China;Technological Research Center of Guangxi Environment Treatment Engineering,Guilin ,Guangxi,China;Key Lab of Guangxi Environment Engineering and Protection Evaluation,Guilin ,Guangxi,China"
            },
            {
                "name": "XU Wen-xin",
                "org": "China Nonferrous Metal%%#Guilin%%# Geology and Mining Co.,Ltd.,Guilin ,Guangxi,China;Technological Research Center of Guangxi Environment Treatment Engineering,Guilin ,Guangxi,China;Key Lab of Guangxi Environment Engineering and Protection Evaluation,Guilin ,Guangxi,China"
            }
        ],
        "venue": "Mineral Resources and Geology",
        "year": 2013
    },
    "qUwWd31i": {
        "id": "qUwWd31i",
        "title": "Problems to be Focused on Ferroalloy Construction Project",
        "abstract": "Several problems are pointed out on environmental impact assessment of ferroalloy construction project based on the shortcomings met in the work,which should be focused on in the future.",
        "keywords": [
            "environmental impact assessment",
            "ferroalloy construction project",
            "problem"
        ],
        "authors": [
            {
                "name": "LIU Jing-jing",
                "org": "Guilin Research Institute of Geology for Mineral Resources,Guilin Guangxi  China"
            },
            {
                "name": "XU Wen-xin",
                "org": "Guilin Research Institute of Geology for Mineral Resources,Guilin Guangxi  China"
            },
            {
                "name": "ZHANG Jing",
                "org": "Guilin Research Institute of Geology for Mineral Resources,Guilin Guangxi  China"
            },
            {
                "name": "LI Heng",
                "org": "Guilin Research Institute of Geology for Mineral Resources,Guilin Guangxi  China"
            }
        ],
        "venue": "Environmental Science Survey",
        "year": 2009
    },
    "oDnf180w": {
        "id": "oDnf180w",
        "title": "Experimental study on artificial fast filtration system for treating rural sewage",
        "abstract": "This research aimed at recognizing sewage processing capacity of artificial soil column composed of different filtration mediums.The result shows that the filter material composed of sand,clinoptilolite and calcite has higher removal rate and hydraulic loading to COD and NH3-N.This filter material combination is used for rural sewage treatment project,the effluent can achieve I level A standard of the urban sewage treatment plants standards for pollutants discharge.",
        "keywords": [
            "filtration mediums",
            "rural sewage",
            "treatment",
            "artificial fast filtration system"
        ],
        "authors": [
            {
                "name": "LI Heng",
                "org": "China Nonferrous Metal%%#Guilin%%# Geology and Mining Co.,Ltd.,Guilin,Guangxi ,China;Guangxi Environmental Control Engineering Research Center,Guilin,Guangxi ,China;Environmental Engineering and Protection Evaluation Key Laboratory,Guilin,Guangxi ,China"
            },
            {
                "name": "HUANG Wei",
                "org": "China Nonferrous Metal%%#Guilin%%# Geology and Mining Co.,Ltd.,Guilin,Guangxi ,China;Guangxi Environmental Control Engineering Research Center,Guilin,Guangxi ,China;Environmental Engineering and Protection Evaluation Key Laboratory,Guilin,Guangxi ,China"
            },
            {
                "name": "XU Wen-xin",
                "org": "China Nonferrous Metal%%#Guilin%%# Geology and Mining Co.,Ltd.,Guilin,Guangxi ,China;Guangxi Environmental Control Engineering Research Center,Guilin,Guangxi ,China;Environmental Engineering and Protection Evaluation Key Laboratory,Guilin,Guangxi ,China"
            },
            {
                "name": "LEI Jin-yong",
                "org": "China Nonferrous Metal%%#Guilin%%# Geology and Mining Co.,Ltd.,Guilin,Guangxi ,China;Guangxi Environmental Control Engineering Research Center,Guilin,Guangxi ,China;Environmental Engineering and Protection Evaluation Key Laboratory,Guilin,Guangxi ,China"
            },
            {
                "name": "ZHANG Jing",
                "org": "China Nonferrous Metal%%#Guilin%%# Geology and Mining Co.,Ltd.,Guilin,Guangxi ,China;Guangxi Environmental Control Engineering Research Center,Guilin,Guangxi ,China;Environmental Engineering and Protection Evaluation Key Laboratory,Guilin,Guangxi ,China"
            },
            {
                "name": "XIAO Xiao-yu",
                "org": "China Nonferrous Metal%%#Guilin%%# Geology and Mining Co.,Ltd.,Guilin,Guangxi ,China;Guangxi Environmental Control Engineering Research Center,Guilin,Guangxi ,China;Environmental Engineering and Protection Evaluation Key Laboratory,Guilin,Guangxi ,China"
            }
        ],
        "venue": "Mineral Resources and Geology",
        "year": 2012
    },
    "bx8jeWSV": {
        "id": "bx8jeWSV",
        "title": "Isotope Geochemistry of the Gaolong Micro-disseminated Gold Deposit in Guangxi",
        "abstract": "S,Pb,H and O isotopic determinations of the ore and gangue minerals in the Gaolong micro-disseminated gold deposit of Guangxi shows that the \u03b434S value of sedimentary pyrite is-15.3 \u2030 \uff5e +13.6 \u2030,the \u03b434S value of pyrite in the ore-bearing bed is +0.4 \u2030 \uff5e +15.6 \u2030,the \u03b434S value of pyrite in siliceous rocks is +1.7 \u2030\uff5e+9.7 \u2030,and the \u03b434S value of stibnite in siliceous rocks is-15.3\u2030 \uff5e+0.1\u2030.The sulfur isotope composition of the pyrite tends to decrease from the ore-bearing bed through the siliceous rocks and to the stibnite in siliceous rocks.The 206Pb/204Pb ratio in pyrite is 18.270\uff5e18.470,the 207Pb/204Pb ratio is 15.620\uff5e15.710,and the 208Pb/204Pb ratio is 38.310\uff5e38.740.The oxygen isotope of quartz in the ore deposit is +11.3 \u2030\uff5e+23.9 \u2030,the oxygen isotope of water is-4.2\u2030\uff5e+14.4\u2030,the hydrogen isotope in mineral inclusions is-53.4\u2030\uff5e-77.1\u2030,the oxygen isotope of calcite in the ore deposit is +10.5\u2030\uff5e+18.6\u2030,the oxygen isotope of water is-3.2\u2030\uff5e+10.7\u2030,and the hydrogen isotope in mineral inclusions is-54.5\u2030\uff5e-30.5\u2030.These data indicate that hydrothermal fluids might have been derived from magmatic hydrothermal solution and atmospheric precipitation as well as ocean waters.",
        "keywords": [
            "Gaolong in Guangxi",
            "micro-disseminated gold deposit",
            "isotope"
        ],
        "authors": [
            {
                "name": "ZHANG Yongzhong",
                "org": ")1)Cenbal South University,Changsha,Changsha,Hunan "
            },
            {
                "name": "LI Heng",
                "org": "Guilin Research Institute of Geology for Mineral Resources,Guilin,Guangxi "
            },
            {
                "name": "LIU Wuhui",
                "org": ")1)Cenbal South University,Changsha,Changsha,Hunan "
            },
            {
                "name": "XU Wenxin",
                "org": "Guilin Research Institute of Geology for Mineral Resources,Guilin,Guangxi "
            },
            {
                "name": "DAI Tagen",
                "org": ")1)Cenbal South University,Changsha,Changsha,Hunan "
            }
        ],
        "venue": "Acta Geoscientica Sinica",
        "year": 2008
    },
    "IG4CxJ8H": {
        "id": "IG4CxJ8H",
        "title": "Isotope geochemistry of the Yejiwei deposit in the Shizhuyuan W-Sn ore field in Hunan province.",
        "abstract": "The Yejiwei deposit from the Shizhuyuan W-Sn ore field in Hunan province occurs in the contact zone between the southeastern edge of the Qianlishan granite and the limestone of the Middle Devonian Qizixiao Group and Upper Devonian Setianqiao Group.This deposit consists of various types of W-Sn-Pb-Zn ores including skarn,greisen,and sulfide mineralization,with clear space distributions.The \u03b4~(18)O values m granite minerals show an overall range from -1.7%0 to+12.1\u2030,in which the quartz has higher \u03b4~(18)O values (8.4\u2030 to 12.2\u2030) than those of K-feldspar (3.8\u2030 to 8.6\u2030) and biotite (-1.7\u2030 to-1.4\u2030).The calculated mineral oxygen isotope equilibrium temperatures (350\u2103 to 630\u2103) are lower than the crystallization temperature of the granite.The \u03b4D values of fluid inclusions in granite quartz vary from -56\u2030 to -62\u2030,which are within the normal magmatic water field.In skarn ores, the calculated fluid \u03b4~(18)O_(H_2O) values range from 8.2\u2030 to 9.2\u2030 and the \u03b4D values are between - 100\u2030 and - 156\u2030.In greisen ores, the calculated fluid \u03b4~(18)O_(H_2O) values range from 4.9\u2030 to 6.7\u2030,and the \u03b4D value is -69\u2030.During sulfide mineralization stage, the calculated fluid \u03b4~(18)O_(H_2O) values range from 2.5\u2030 to -6.1\u2030,and the \u03b4D value is -54.2\u2030.In the latest stage of quartz veins, the calculated fluid\u03b4~(18)O_(H_2O) vlue is - 7.3\u2030 and the \u03b4D value is -57.7\u2030.The oxygen and hydrogen isotope variations from the early skarn ore stage to late quartz vein stage can be better explained by fluid degassing and fluid mixing between magmatic fluids and meteoric water.The host rocks of limestone and marble show \u03b4~(18) O values of 4.2\u2030 to 20.0\u2030,and \u03b4~(13) C_(PDB) values of - 6.0\u2030 to 0.3\u2030.This large isotopic variation can be better explained by fluid-rock interaction and isotope exchange during mineralization and aheration.The sulfide minerals in the deposit show a total \u03b4~(34)S variation from + 2.8\u2030 to + 8.9\u2030.In the skarn ores,the \u03b4~(34)S values are +2.8\u2030 to + 8.9\u2030,whereas in the greisen ores the b'-~4S values show a narrower range from + 3.4\u2030 to + 6.9\u2030.In the sulfide inineralization stage,the \u03b4~(34)S values vary from + 3.7\u2030 to + 6.3\u2030.The value of \u03b4~(34)S_(\u03a3S) is estimated to be \uff5e3\u2030,suggesting that the sulfur may mainly come from the Qianlishan granite magma.We suggest that the ore material sources of the Yejiwei deposit largely derived from the Qianlishan granite,but minor proportion may also come from the host sedimentary rocks.",
        "keywords": [
            "Hunan",
            "Stable isotopes",
            "W-Sn mineralization",
            "Yejiwei deposit"
        ],
        "authors": [
            {
                "name": "LIU WuHui",
                "org": ""
            },
            {
                "name": "XU WenXin",
                "org": "Guilin Research Institute of Geology for Mineral Resources,Guilin ,China"
            },
            {
                "name": "DAI TaGen",
                "org": ""
            },
            {
                "name": "LI Heng",
                "org": "Guilin Research Institute of Geology for Mineral Resources,Guilin ,China"
            }
        ],
        "venue": "Acta Petrologica Sinica",
        "year": 2006
    },
    "byG2rIHc": {
        "id": "byG2rIHc",
        "title": "Study on the Acid Modified Stellerite Characteristics",
        "abstract": "Physical specific surface area,scanning electronic microscopy,infrared spectrum,X-ray diffraction and thermal differential means are utilized to characterize ore properties of acid modified stellerite.Stellerite's specific surface area,pore volume and impurities of origin ore will change with acid modified treatment.This improves the absorption and exchange capacities and pollution treatment capabilities of modified stellerite.",
        "keywords": [
            "characterization method",
            "acid modification",
            "stellerite"
        ],
        "authors": [
            {
                "name": "GU Zhan-qi",
                "org": "1.Environmental Protection Science Research Institute of Guangxi Zhuang Autonomous Region "
            },
            {
                "name": "LI Heng",
                "org": "2.Guilin Research Institute of Geology for Mineral Resources"
            },
            {
                "name": "ZHANG Jing",
                "org": "2.Guilin Research Institute of Geology for Mineral Resources"
            },
            {
                "name": "XIAO Xiao-yu",
                "org": "2.Guilin Research Institute of Geology for Mineral Resources"
            }
        ],
        "venue": "Mineral Resources and Geology",
        "year": 2010
    },
    "Ll0VqBMk": {
        "id": "Ll0VqBMk",
        "title": "Isotope Geochemistry of the Xianghualing Tin-Polymetallic Deposit in Hunan Province",
        "abstract": "According to the temperatures of inclusions in minerals and S and Pb isotopic determinations of the minerals formed at different ore-forming stages in the Xianghualing tin-polymetallic deposit,it is revealed that the homogeneous temperature of the cassiterite-sulfide phase is 350\u2103,the average homogenization temperature of the sulfide-stage is 250\u2103,the \u03b434S value of pyrite in sulfide is-1.0 \u2030\uff5e+5.4\u2030,the \u03b434S value of sphalerite is +0.8\u2030\uff5e+5.8\u2030,the \u03b434S value of pyrrhotite is +1.5 \u2030\uff5e5.2\u2030,and the \u03b434S value of galena is-1.0\u2030 \uff5e +3.6\u2030,characterized by insignificant variation and stable composition.The 206Pb/204Pb ratio of galena is 17.785\uff5e19.341,the 207Pb/204Pb ratio is 15.416\uff5e16.452,and the 208Pb/204Pb ratio is 38.357 \uff5e42.579.The S isotopes indicate that they were derived from the magma,and the Pb isotopes suggest that they came from mixed sources.",
        "keywords": [
            "tin-polymetallic deposit",
            "Hunan",
            "Xianghualing",
            "isotope"
        ],
        "authors": [
            {
                "name": "ZHOU Tao",
                "org": "1)Central South University,Changsha,Hunan "
            },
            {
                "name": "LIU Wuhui",
                "org": "1)Central South University,Changsha,Hunan "
            },
            {
                "name": "LI Heng",
                "org": "Guilin Research Institute of Geology for Mineral Resources,Guilin,Guangxi "
            },
            {
                "name": "XU Wenxin",
                "org": "Guilin Research Institute of Geology for Mineral Resources,Guilin,Guangxi "
            },
            {
                "name": "DAI Tagen",
                "org": ""
            }
        ],
        "venue": "Acta Geoscientica Sinica",
        "year": 2008
    },
    "ierOTBz1": {
        "id": "ierOTBz1",
        "title": "Present State and utilization Research of Solid Wastes of Nonferrous Metal Mine in Guangxi",
        "abstract": "Mining industry of every country in the world discharge a great quantity of mining solid wastes such as tailings and waste stone,if these solid wastes are not processed timely,they will occupy land,pollute environment,even severely affect human life.This article comments on several processing methods for treatment of nonferrous mine solid wastes in Guang Xi,and puts forward corresponding countermeasure.",
        "keywords": [
            "solid waste",
            "comprehensive utilization",
            "nonferrous mine"
        ],
        "authors": [
            {
                "name": "LI Heng",
                "org": "Guilin Research Institute of Geology for Mineral Resources,Guilin,Guangxi ,China;Key Lab of Environmental Engineering & Protection Evaluation,Guilin,Guangxi ,China"
            },
            {
                "name": "XU Wen-xin",
                "org": "Guilin Research Institute of Geology for Mineral Resources,Guilin,Guangxi ,China;Key Lab of Environmental Engineering & Protection Evaluation,Guilin,Guangxi ,China"
            },
            {
                "name": "LI Xiang-lan",
                "org": "Environment Protection Technology Center of Guangxi,Nanning,Guangxi ,China;Key Lab of Environmental Engineering & Protection Evaluation,Guilin,Guangxi ,China"
            }
        ],
        "venue": "Yunnan Metallurgy",
        "year": 2011
    },
    "sQF9xqpo": {
        "id": "sQF9xqpo",
        "title": "Study on clinoptilolite mineral materials for treating sewage",
        "abstract": "The clinoptilolite mineral materials in this study belong to monoclinic crystal system with the white and light yellow color,the hardness of about 4,dielectric constant between 7.0 and 7.5,and specific gravity of 2.16.The scanning electron microscope picture shows that this clinoptilolite is wide board strips,thin board strips,irregular granular etc.,grain diameter is between 0.02 and 0.05mm,length-width ratio is 4\u22361.The chemical composition analysis shows that SiO2 is 69.12wt%,Al2O3 is 11.27 wt%,CaO is 7.13 wt%,K2O is 2.26 wt%,NaO is 1.94 wt%,ignition loss is 9.12 wt%,H2O is 7.38 wt%.X-ray diffraction shows that diffraction peak is mainly caused by clinoptilolite and the impurity is SiO2.The clinoptilolite is used for treating sewage as contact oxidation filler,the effluent can achieve state relevant discharge standard.",
        "keywords": [
            "sewage",
            "treatment",
            "contact oxidation",
            "clinoptilolite",
            "filler"
        ],
        "authors": [
            {
                "name": "XU Wen-xin",
                "org": "Guilin Research Institute of Geology for Mineral Resources,Guilin,Guangxi ,China;Guangxi Environmental Control Engineering Research Center,Guilin,Guangxi ,China;Environmental Engineering and Protection Evaluation Key Laboratory,Guilin,Guangxi ,China"
            },
            {
                "name": "LI Heng",
                "org": "Guilin Research Institute of Geology for Mineral Resources,Guilin,Guangxi ,China;Guangxi Environmental Control Engineering Research Center,Guilin,Guangxi ,China;Environmental Engineering and Protection Evaluation Key Laboratory,Guilin,Guangxi ,China"
            },
            {
                "name": "HUANG Wei",
                "org": "Guilin Research Institute of Geology for Mineral Resources,Guilin,Guangxi ,China;Guangxi Environmental Control Engineering Research Center,Guilin,Guangxi ,China;Environmental Engineering and Protection Evaluation Key Laboratory,Guilin,Guangxi ,China"
            },
            {
                "name": "LEI Jin-yong",
                "org": "Guilin Research Institute of Geology for Mineral Resources,Guilin,Guangxi ,China;Guangxi Environmental Control Engineering Research Center,Guilin,Guangxi ,China;Environmental Engineering and Protection Evaluation Key Laboratory,Guilin,Guangxi ,China"
            },
            {
                "name": "ZHANG Jing",
                "org": "Guilin Research Institute of Geology for Mineral Resources,Guilin,Guangxi ,China;Guangxi Environmental Control Engineering Research Center,Guilin,Guangxi ,China;Environmental Engineering and Protection Evaluation Key Laboratory,Guilin,Guangxi ,China"
            },
            {
                "name": "XIAO Xiao-yu",
                "org": "Guilin Research Institute of Geology for Mineral Resources,Guilin,Guangxi ,China;Guangxi Environmental Control Engineering Research Center,Guilin,Guangxi ,China;Environmental Engineering and Protection Evaluation Key Laboratory,Guilin,Guangxi ,China"
            }
        ],
        "venue": "Mineral Resources and Geology",
        "year": 2011
    },
    "6FB1kZ4N": {
        "id": "6FB1kZ4N",
        "title": "Geochemical evidence for formation of sulfur and lead isotope in Keketale Pb-Zn deposit in Xinjiang",
        "abstract": "According to the study on physical and chemical conditions and sulfur and lead isotope of Keketale Pb-Zn deposit in Xinjiang,it can be concluded that the deposit formation temperature is 300\u2103;logfS2 is-32.75~-33.91,logfS2 is-6.75~-10.00;pH is 5.3~7.0.The ratio of 206Pb/204Pb,207Pb/204Pb and 208Pb/204Pb in ore and gangue are 18.001~18.200,15.480~ 15.705 and 37.605~38.861 respectively.The ratio of 206Pb/204Pb,207Pb/204Pb,and 208Pb/204Pb in sulfide are 18.001~18.176,15.480~ 15.634,and 37.605~38.027,respectively.The ratio of 206Pb/204Pb,207Pb/204Pb,and 208Pb/204Pb in gossan are 18.017~18.200,15.509~ 15.617,and 37.833~38.283,respectively.The ratio of 206Pb/204Pb,207Pb/204Pb,and 208Pb/204Pb in barite and quartz are 18.014~18.027,15.482~ 15.495,and 37.632~37.675,respectively.The \u03b434S of sulfide is in the range of-15.8\u2030~+5.1\u2030,\u03b434S of pyrite is in the range of-14.3\u2030~+5.1\u2030,\u03b434S of galena is in the range of-15.8\u2030~-1.0\u2030,\u03b434S of magnetic pyrite is in the range of-14.6\u2030~-1.4\u2030,\u03b434S of zinc blende is in the range of-14.5\u2030~-11.3\u2030.Sulfur isotope indicates that sulfur originates from magma,while lead isotope indicates that lead comes from multiple sources.",
        "keywords": [
            "mineralization material source",
            "Pb-Zn deposit",
            "isotope"
        ],
        "authors": [
            {
                "name": "XU Wen-xin",
                "org": "China Nonferrous Metal%%#Guilin%%# Geology and Mining Co.,Ltd.,Guilin ,Guangxi,China"
            },
            {
                "name": "LI Heng",
                "org": "China Nonferrous Metal%%#Guilin%%# Geology and Mining Co.,Ltd.,Guilin ,Guangxi,China"
            },
            {
                "name": "CHEN Min-yang",
                "org": "China Nonferrous Metal%%#Guilin%%# Geology and Mining Co.,Ltd.,Guilin ,Guangxi,China"
            }
        ],
        "venue": "Mineral Resources and Geology",
        "year": 2012
    },
    "tnVCBl8b": {
        "id": "tnVCBl8b",
        "title": "Experimental study on mechanical performance of new corrosion resistant tie for cavity wall",
        "abstract": "In order to solve the corrosion resistant problem of steel tie for cavity wall,the mechanical performance of new corrosion resistant tie,i.e.,plastic steel tie,was investigated.The tensile status of Z-shaped and ring shaped plastic steel ties were simulated through an experiment on mortar joint sample of Lshaped and U-shaped plastic steel ties.The uneven forcing characteristics of ring shaped plastic steel tie were studied through performing the unilateral alternate drawing experiment on ring shaped plastic steel tie.The experimental results show that the tensile properties and deformation performance of plastic steel tie are more superior to those of general steel tie.With suffering large earthquak,the maximum earthquake force transferred by plastic steel tie is far less than the minimum ultimate drawing force.It indicates that the mechanical performance of ring shaped plastic steel tie can satisfy the usage requirement for cavity wall.Through analyzing the factors affecting on anchoring force of plastic steel tie,new form of plastic steel tie was proposed and the design parameter suggestion for various plastic steel tie was given.In addition,some suggestions for construction measures and selection rules of plastics steel tie were presented with refering to the related criterions.",
        "keywords": [
            "Cavity wall",
            "Construction measure",
            "Corrosion resistant",
            "Deformation performance",
            "Drawing test",
            "Mechanical performance",
            "Parameter design",
            "Tie"
        ],
        "authors": [
            {
                "name": "ZHANG Yan-nian",
                "org": "School of Civil Engineering,Shenyang Jianzhu University,Shenyang ,China"
            },
            {
                "name": "LI Heng",
                "org": "School of Civil Engineering,Shenyang Jianzhu University,Shenyang ,China"
            },
            {
                "name": "LIU Ming",
                "org": "School of Civil Engineering,Shenyang Jianzhu University,Shenyang ,China"
            },
            {
                "name": "ZHANG Xun",
                "org": "School of Civil Engineering,Shenyang Jianzhu University,Shenyang ,China"
            },
            {
                "name": "LI Li-dong",
                "org": "School of Civil Engineering,Shenyang Jianzhu University,Shenyang ,China"
            }
        ],
        "venue": "Journal of Shenyang University of Technology",
        "year": 2010
    },
    "lO5hjw0Y": {
        "id": "lO5hjw0Y",
        "title": "Study of anti-seismic shear resistance capacity of foam-in-place cavity walls",
        "abstract": "In order to solve the durability problem of energy-efficient walls,foam-in-place cavity walls,a new type of energy-efficient walls,is proposed,and its seismic behavior is studied.13 patches of cavity walls and 1 patch of solid wall are built and seismic tests are carried out.The effects of constructional measures on the mechanical behavior and deformation properties of the walls and the effects of vertical pressure and insulation layer thickness on the relative displacement difference of the internal and external walls of foam-in-place cavity wall are analyzed.The experimental study shows that reinforced concrete strip ears play an important role in guaranteeing out-plane stability of the external wall.When wall crack seriously,the ties can play an important role in supporting the wall and preventing wall collapse.The reinforced concrete strip ears and ties are the main constructional measures to coordinate the internal and external walls.Moreover,deformation capacity of the cavity wall is improved efficiently with constructional columns.Because of the interactive working between the internal and external wall of foam-in-place cavity wall,the beneficial effects of the external wall of foam-in-place cavity wall should be considered when anti-seismic shear resistance capacity is calculated.Computational model of compound section shearing resistance is used,and the cooperation coefficient of the internal and external walls of foam-in-place cavity wall is given according to the test result regression analysis.A calculation formula for the anti-seismic shear resistance capacity of foam-in-place cavity wall is derived.Both the standard deviation and the coefficient of variation meet the standard requirements,which shows that the calculation results are in good agreement with the measured ones.",
        "keywords": [
            "cavity wall",
            "constructional measure",
            "seismic test",
            "seismic capacity",
            "stability"
        ],
        "authors": [
            {
                "name": "Zhang Yannian",
                "org": "Shenyang Jianzhu University,Shenyang ,China"
            },
            {
                "name": "Li Heng",
                "org": "Shenyang Jianzhu University,Shenyang ,China"
            },
            {
                "name": "Liu Ming",
                "org": "Shenyang Jianzhu University,Shenyang ,China"
            },
            {
                "name": "Zhang Xun",
                "org": "Shenyang Jianzhu University,Shenyang ,China"
            },
            {
                "name": "Li Lidong",
                "org": "Shenyang Jianzhu University,Shenyang ,China"
            }
        ],
        "venue": "China Civil Engineering Journal",
        "year": 2011
    },
    "OZohEy7m": {
        "id": "OZohEy7m",
        "title": "STUDY ON THE IN-PLANE DEFORMATION BEHAVIOR OF FOAM-IN-PLACE CAVITY WALL",
        "abstract": "In order to study the in-plane deformation behavior of a new energy-saving wall,namely the foam-in-place cavity wall,13 patches of cavity walls and 1 patch of solid wall were built and tested.The dynamic hysteretic loop curves,the backbone curves and time history curves of displacement were obtained considering the variation of heights,ductility,energy dissipation and stiffness degradation.The effects of axial compression ratio,shape and layout of ties,and insulation layer thickness on structural seismic behaviors were investigated.The experimental results show that the deformation capacity and the overall performance of the cavity wall is improved efficiently with constructional columns,ties and reinforced concrete strip ears,and the cavity walls have good deformation and energy dissipation behaviors.",
        "keywords": [
            "deformation behavior",
            "constructional measure",
            "seismic test",
            "in-plane loading",
            "low cyclic loadings",
            "foam-in-place cavity wall"
        ],
        "authors": [
            {
                "name": "ZHANG Yan-nian",
                "org": "School of Civil Engineering,Shenyang Jianzhu University,Shenyang,Liaoning ,China"
            },
            {
                "name": "LI Heng",
                "org": "School of Civil Engineering,Shenyang Jianzhu University,Shenyang,Liaoning ,China"
            },
            {
                "name": "LIU Ming",
                "org": "School of Civil Engineering,Shenyang Jianzhu University,Shenyang,Liaoning ,China"
            },
            {
                "name": "ZHANG Xun",
                "org": "School of Civil Engineering,Shenyang Jianzhu University,Shenyang,Liaoning ,China"
            },
            {
                "name": "LI Li-dong",
                "org": "School of Civil Engineering,Shenyang Jianzhu University,Shenyang,Liaoning ,China"
            }
        ],
        "venue": "Engineering Mechanics",
        "year": 2011
    },
    "xAd1w1Wd": {
        "id": "xAd1w1Wd",
        "title": "Interaction Working Behavior About the Internal and External Wall of Foam-in-place Cavity Wall",
        "abstract": "In order to study the stability of foam-in-place cavity wall,the capacity of reinforced concrete strip ear and tie involving in cavity wall deformation,the broken shapes and mechanical performance of the cavity wall,the effective measures was seaked to improve deformation capacity and overall performance of the cavity wall.13 patches of cavity wall and 1 patch of solid wall were built and seismic tests of which were carried out.The lnfluence of some constructional measures on mechanical behavior and deformation properties of the wall and vertical pressure and insulation layer thickness on the relative displacement difference of the internal and external wall of foam-in-place cavity wall was analyzed.Finally,the capability of reinforced concrete strip ear and tie working interactively between the internal and external wall of foam-in-place cavity wall was analyzed.It is found that deformation capacity of the cavity wall is improved efficiently with constructional column and the high bonding strength,shearing strength and pressure strength of foam-in-place insulating mortar have certainly a positive influence on the bearing capacity of the wall.The reinforced concrete strip ears play the leading role in reinforcing connection of the internal and external wall of foam-in-place cavity wall and guaranteeing out-plane stability of the external wall.When walls crack seriously,the ties can play an important role in supporting and drawing the wall and preventing wall collapse.Furthermore,the reinforced concrete strip ears and ties which are the main construction measures to coordinate the internal and external wall work together perform a great variety of tasks.Therefore,the reinforced concrete strip ears and ties should be designed rationally to guarantee playing their respective roles.",
        "keywords": [
            "cavity wall",
            "constructional measure",
            "seismic test",
            "deformation capacity",
            "stability"
        ],
        "authors": [
            {
                "name": "ZHANG Yan-nian",
                "org": "Department of Civil Engineering,Tsinghua University,Beijing ,China;School of Civil Engineering,Shenyang Jian Zhu University,Shenyang ,China"
            },
            {
                "name": "LI Heng",
                "org": "School of Civil Engineering,Shenyang Jian Zhu University,Shenyang ,China"
            },
            {
                "name": "LIU Ming",
                "org": "School of Civil Engineering,Shenyang Jian Zhu University,Shenyang ,China"
            },
            {
                "name": "ZHANG Xun",
                "org": "School of Civil Engineering,Shenyang Jian Zhu University,Shenyang ,China"
            },
            {
                "name": "LI Li-dong",
                "org": "School of Civil Engineering,Shenyang Jian Zhu University,Shenyang ,China"
            }
        ],
        "venue": "Journal of Civil,Architectural & Environmental Engineering",
        "year": 2010
    },
    "98xkec8D": {
        "id": "98xkec8D",
        "title": "THE MODEL TESTS AND NUMERICAL TESTS OF OUT-PLANE SEISMIC PROPERTY OF FOAM-IN-PLACE CAVITY WALL",
        "abstract": "In order to study on the out-plane seismic property of foam-in-place cavity walls,and seek the effective measures to improve the deformation capacity and overall performance of a cavity wall,7 patches of foam-in-place cavity walls and 1 patch of a solid wall are built,and the model tests and numerical tests of out-plane seismic properties are carried out.The comparison indicates that the failure patterns,carrying capacity,deformation ability and coordination deformation ability of the numerical tests are agree with the data of model tests,and that the validity and accuracy of the model tests and numerical tests are both verified.The research shows that reinforced concrete transverse connecting beams play an important role in guaranteeing out-planes stability of the external wall.When wall cracks seriously,the steel ties coated plastic can play an important role in preventing the wall from collapse.The research results of deformation behavior show that foam-in-place cavity walls have the better ductility and energy dissipation and the internal as well as external wall of foam-in-place cavity wall have very well coordinating deformation capacity.",
        "keywords": [
            "cavity wall",
            "model tests",
            "deformation capacity",
            "numerical tests",
            "coordination deformation capacity",
            "seismic behavior",
            "carrying capacity"
        ],
        "authors": [
            {
                "name": "ZHANG Yan-nian",
                "org": "Department of Civil Engineering,Tsinghua University,Beijing ,China;School of Civil Engineering,Shenyang Jianzhu University,Shenyang ,China"
            },
            {
                "name": "WANG Yuan-qing",
                "org": "Department of Civil Engineering,Tsinghua University,Beijing ,China"
            },
            {
                "name": "LI Heng",
                "org": "School of Civil Engineering,Shenyang Jianzhu University,Shenyang ,China"
            },
            {
                "name": "SHI Yong-jiu",
                "org": "Department of Civil Engineering,Tsinghua University,Beijing ,China"
            },
            {
                "name": "LIU Ming",
                "org": "School of Civil Engineering,Shenyang Jianzhu University,Shenyang ,China"
            },
            {
                "name": "ZHANG Xun",
                "org": "School of Civil Engineering,Shenyang Jianzhu University,Shenyang ,China"
            }
        ],
        "venue": "Engineering Mechanics",
        "year": 2012
    },
    "JXlRmqsr": {
        "id": "JXlRmqsr",
        "title": "Experimental Study on Anchorage Performance of Ring Shaped Plastic Steel Tie for Cavity Walls",
        "abstract": "In order to solve corrosion resistance problem of the steel tie for cavity walls and study its bond behavior and anchorage performance,plastic steel ties were designed and made.Tensile status of the ring shaped plastic steel tie was simulated through an experiment of mortar joint sample of u-shaped plastic steel ties.Uneven force characteristics of ring shaped plastic steel ties were studied through an experiment of unilateral alternate drawing of u-shaped plastic steel ties.The average value of ultimate drawing force of each group u-shaped plastic steel ties was 9.5-13.7 kN.The minimum value of ultimate drawing force was 9.1 kN.Maximum earthquake force transferred by plastic steel tie was far less than the minimum value of ultimate drawing force when suffering from large earthquakes.Bearing capacity could be kept when u-shaped plastics steel ties drew unilateral alternate with large deformation capacity.The results by exemplification show that mechanical behavior of ring shaped plastic steel ties can satisfy the use requirement of cavity walls.The tensile properties and deformation performance of plastic steel tie for cavity walls are superior to those of general steel ties.",
        "keywords": [
            "cavity wall",
            "constructional measure",
            "plastics steel tie",
            "mechanical anchorage",
            "tensile test"
        ],
        "authors": [
            {
                "name": "ZHANG Yannian",
                "org": "School of Civil Engineering,Shenyang Jianzhu University,Shenyang China,"
            },
            {
                "name": "ZHANG Xun",
                "org": "School of Civil Engineering,Shenyang Jianzhu University,Shenyang China,"
            },
            {
                "name": "LIU Ming",
                "org": "School of Civil Engineering,Shenyang Jianzhu University,Shenyang China,"
            },
            {
                "name": "LI Lidong",
                "org": "School of Civil Engineering,Shenyang Jianzhu University,Shenyang China,"
            },
            {
                "name": "LI Heng",
                "org": "School of Civil Engineering,Shenyang Jianzhu University,Shenyang China,"
            }
        ],
        "venue": "Journal of Shenyang Jianzhu University(Natural Science)",
        "year": 2008
    },
    "phSf8E8m": {
        "id": "phSf8E8m",
        "title": "Experimental Study on Anchorage Performance of L-Shaped Plastics Steel Tie for Cavity Wall",
        "abstract": "In order to solve corrosion resistance problem of steel tie for cavity wall,plastics steel ties were made of high-tensile reinforcing steel and lagging plastic.A G steel tie lagging plastic would transfer its bond behavior and anchorage performance between steel tie and mortar and tensile status of Z-shaped plastics steel tie was simulated through an experiment of mortar joint sample of L-shaped plastics steel ties,we went into the bond behavior and anchorage performance between Z-shaped plastics steel tie and mortar.The average value of ultimate drawing force of each group L-shaped plastics steel ties was 3.33~4.4 kN.The minimum value of ultimate drawing force was 2.9 kN.Maximum earthquake force transferred by plastics steel tie was far less than the minimum value of ultimate drawing force when suffering large earthquake.The results by exemplification show that mechanical behavior of L-shaped plastics steel tie can satisfy the use requirement for cavity wall.The tensile properties and deformation performance of plastics steel tie for cavity wall are more superior to that of general steel tie.At last,through analyses of bond behavior and anchorage performance influencing factor,we give Z-shaped and flanging Z-shaped plastics steel tie\u2032s proper structural parameter.",
        "keywords": [
            "anchorage length",
            "pull-out test",
            "plastics steel tie",
            "bearing capacity"
        ],
        "authors": [
            {
                "name": "LIU Ming",
                "org": "School of Civil Engineering,Shenyang Jianzhu University,Shenyang China,"
            },
            {
                "name": "LI Lidong",
                "org": "School of Civil Engineering,Shenyang Jianzhu University,Shenyang China,"
            },
            {
                "name": "ZHANG Yannian",
                "org": "School of Civil Engineering,Shenyang Jianzhu University,Shenyang China,"
            },
            {
                "name": "ZHANG Xun",
                "org": "School of Civil Engineering,Shenyang Jianzhu University,Shenyang China,"
            },
            {
                "name": "LI Heng",
                "org": "School of Civil Engineering,Shenyang Jianzhu University,Shenyang China,"
            }
        ],
        "venue": "Journal of Shenyang Jianzhu University(Natural Science)",
        "year": 2009
    },
    "GQhmsay8": {
        "id": "GQhmsay8",
        "title": "Study on characteristics of vertical to horizontal acceleration response spectral ratio",
        "abstract": "In this paper,3225 strong ground motion records from 128 earthquakes are used to calculate the ratios of the vertical to horizontal acceleration response spectra(V/H).The records are divided into groups according to site condition,epicentral distance,magnitude and focal mechanism.This study focuses on the relationship between V/H and these factors.The results show that:(1) the harder the site is,the larger the V/H in long-period range becomes,and the V/H in short-period range is opposite.(2) The greater the magnitude is,the higher the V/H in long-period range becomes,but the V/H in short period is not impressible.(3) The V/H in short period decreases as epicentral distance increases.(4) For great magnitude(M>7),the V/H in long-period range reduces as the epicentral distance increases.However,for great-moderate earthquakes(M<7),the ratio increases with the epicentral distance in near-field,and it reduces as the epicentral distance increases in far-field.(5) The V/H is also related to focal mechanism.",
        "keywords": [
            "focal mechanism",
            "acceleration response spectra",
            "site condition",
            "vertical ground motion"
        ],
        "authors": [
            {
                "name": "LI Heng",
                "org": "Institute of Seismology,China Earthquake Administration,Wuhan ,China;Wuhan Institute of Earthquake Engineering,Wuhan ,China"
            },
            {
                "name": "QIN Xiaojun",
                "org": "Institute of Seismology,China Earthquake Administration,Wuhan ,China"
            }
        ],
        "venue": "Journal of Earthquake Engineering and Engineering Vibration",
        "year": 2010
    },
    "McY03zaR": {
        "id": "McY03zaR",
        "title": "Analysis of Statistic Characteristics of Peak Ratios in Vertical and Horizontal Ground Motion Acceleration",
        "abstract": "In this paper,the statistic analysis of peak ratios in vertical and horizontal acceleration(V/H)is done by using strong ground motion data.It is shown that V/H obeys the lognormal distribution.Based on the data,the effects of magnitude,epicentral distance,site conditions,and focal mechanism on V/H are analyzed.The results show that the effect of magnitude is inconspicuous,and V/H is reduced as the epicentral distance is increased,especially on soft soil site.In the near-field(R\u226460 km),V/H on soil site is bigger than it on rock site,and it is opposite in the far-field.In addition,the focal mechanism affects to V/H greatly,especially in the near-field.",
        "keywords": [
            "focal mechanism",
            "lognormal distribution",
            "acceleration peak ratio",
            "vertical ground motion"
        ],
        "authors": [
            {
                "name": "LI Heng",
                "org": "Institute of Seismology,CEA,Wuhan ,Hubei,China;Earthquake Administration of Hubei Province,Wuhan ,Hubei,China"
            },
            {
                "name": "LI Jing-gang",
                "org": "Institute of Seismology,CEA,Wuhan ,Hubei,China"
            },
            {
                "name": "WANG Dun",
                "org": "Institute of Seismology,CEA,Wuhan ,Hubei,China"
            },
            {
                "name": "CAI Yong-jian",
                "org": "Institute of Seismology,CEA,Wuhan ,Hubei,China;Earthquake Administration of Hubei Province,Wuhan ,Hubei,China"
            }
        ],
        "venue": "Journal of Seismological Research",
        "year": 2010
    },
    "HN3qvTzT": {
        "id": "HN3qvTzT",
        "title": "PEAK VELOCITY ATTENUATION RELATIONS OF THE EARTHQUAKES IN HUBEI AND ITS ADJACENT AREA",
        "abstract": "Peak ground velocity(PGV) is very important to some large structures and buried pipelines.Taking the south California of America which has rich strong ground motion records and seismic intensity data as the reference combining the seismic intensity attenuation relation data we have obtained the PGV attenuation relation of Hubei and its adjacent region by use of the transmission method.",
        "keywords": [
            "attenuation",
            "parameter",
            "conversing method",
            "seismic intensity",
            "peak ground velocity"
        ],
        "authors": [
            {
                "name": "Han Xiqin",
                "org": "%%# Institute of Seismology,CEA,Wuhan 2) Wuhan Institute of Earthquake Engineering,Wuhan )"
            },
            {
                "name": "Li Heng",
                "org": "%%# Institute of Seismology,CEA,Wuhan 2) Wuhan Institute of Earthquake Engineering,Wuhan )"
            },
            {
                "name": "Cai Yongjian",
                "org": "%%# Institute of Seismology,CEA,Wuhan 2) Wuhan Institute of Earthquake Engineering,Wuhan )"
            }
        ],
        "venue": "Journal of Geodesy and Geodynamics",
        "year": 2010
    },
    "TH5OQ2wT": {
        "id": "TH5OQ2wT",
        "title": "IMPROVEMENT OF RELOCATION PROGRAM BASED ON DOUBLE-DIFFERENCE(DD) ALGORITHM",
        "abstract": "Considering that the double-difference relocation program provided by Waldhauser wastes lots of memories because of using static array,a new method to improve the program by use of dynamically allocatable array is presented.The example offered along with the programs can run on 256MB instead of 1.4 GB memory with the same speed.",
        "keywords": [
            "dynamically allocatable array",
            "double-difference relocation",
            "program improvement",
            "static array",
            "global variable"
        ],
        "authors": [
            {
                "name": "Yao Yunsheng",
                "org": "Institute of Seismology,CEA,Wuhan 2)Crustal Movement Laboratory,Wuhan "
            },
            {
                "name": "Li Jinggang",
                "org": "Institute of Seismology,CEA,Wuhan 2)Crustal Movement Laboratory,Wuhan "
            },
            {
                "name": "Lian Chao",
                "org": "Institute of Seismology,CEA,Wuhan 2)Crustal Movement Laboratory,Wuhan "
            },
            {
                "name": "Song Chen",
                "org": "Institute of Seismology,CEA,Wuhan 2)Crustal Movement Laboratory,Wuhan "
            },
            {
                "name": "Li Heng",
                "org": "Institute of Seismology,CEA,Wuhan 2)Crustal Movement Laboratory,Wuhan "
            },
            {
                "name": "Li Shengle",
                "org": "Institute of Seismology,CEA,Wuhan 2)Crustal Movement Laboratory,Wuhan "
            }
        ],
        "venue": "Journal of Geodesy and Geodynamics",
        "year": 2007
    },
    "zUhnxq7h": {
        "id": "zUhnxq7h",
        "title": "STUDY OF QUATERNARY ACTIVITY AND TECTONIC DEFORMATION MECHNISM OF MACHENG-TUANFENG FAULT BELT",
        "abstract": "On the basis of geological survey of tectonic landform and drainage as well as fault feature to the middle segment of Macheng-Tuanfeng fault belt,this paper involves its quaternary activity characteristic in seismology and geology and discusses on the tectonic deformation mechanism of the fault,combining the depth of earthquake source in study area.The preliminary analysis can be drawn from this study.The fault,which is characterized by normal faulting and right-lateral offset,is predominantly active in the middle Pleistocene and is weakening in the Late Pleistocene.The drainage offset is up to 2-3 km in the way of dextral motion.The host fault controls the branch fault and they share a sliping plane in the crust.The differential uplifting of crust and mantle depth,as well as regionally tectonic principal pressure stress field of NE-NEE orientation provide the fault motion with dynamic force source.",
        "keywords": [
            "seismicity",
            "tectonic stress field",
            "tectonic deformation",
            "Macheng-Tuanfeng fault",
            "Quaternary activity"
        ],
        "authors": [
            {
                "name": "Lei Dongning",
                "org": "%%#Institute of Seismology,China Earthquake Administration,Wuhan ;Institute of Earthquake Engineering of Wuhan,Wuhan "
            },
            {
                "name": "Cai Yongjian",
                "org": "%%#Institute of Seismology,China Earthquake Administration,Wuhan ;Institute of Earthquake Engineering of Wuhan,Wuhan ;Faculty of Earth Science,China University of Geosciences,Wuhan )"
            },
            {
                "name": "Zheng Shuiming",
                "org": "%%#Institute of Seismology,China Earthquake Administration,Wuhan ;Institute of Earthquake Engineering of Wuhan,Wuhan "
            },
            {
                "name": "Li Heng",
                "org": "%%#Institute of Seismology,China Earthquake Administration,Wuhan ;Institute of Earthquake Engineering of Wuhan,Wuhan "
            }
        ],
        "venue": "Journal of Geodesy and Geodynamics",
        "year": 2012
    },
    "vt53uNHE": {
        "id": "vt53uNHE",
        "title": "DRAWING EPICENTRE DISTRIBUTION MAP BASED ON SECONDARY DEVELOPMENT OF MapGIS",
        "abstract": "MapGIS does well in map drawing,but appending dots representing epicenter in seismic tectonic map is an actually tedious work.A method that concludes following steps is presented.Firstly,convert the text file recording earthquake information into the clear text of MapGIS,sencondly,create graphic file from the clear text,finally,connect attribute for dynamically marking.According to the above procedure,taking Microsoft VC++6.0 as the tool,drawing epicentre distribution map based on secondary development of MapGIS can be realized fast and accurately.",
        "keywords": [
            "secondary development",
            "MapGIS",
            "epicenter distribution map",
            "attribute connection",
            "clear text"
        ],
        "authors": [
            {
                "name": "Li Heng",
                "org": "Institute of Seismology,CEA,Wuhan "
            },
            {
                "name": "Yao Yunsheng",
                "org": "Institute of Seismology,CEA,Wuhan "
            },
            {
                "name": "Chen Shujun",
                "org": "Institute of Seismology,CEA,Wuhan "
            }
        ],
        "venue": "Journal of Geodesy and Geodynamics",
        "year": 2007
    },
    "kFezlWSw": {
        "id": "kFezlWSw",
        "title": "Numerical Simulation of Equivalent Stress Field after the Impoundment of the Three Gorges Reservoir and the Seismogenic Mechanism of Hujiaping M_S4.1 Earthquake",
        "abstract": "Using finite element method,we established a 3D linear elastic finite element model of the head area of the Three Gorges Reservoir after the Hujiaping MS4.1 earthquake occurred after the 172 m level experimental impoundment.Then we calculated and obtained the equivalent stress field under 172 m water level and that in 8 km depth in the head area of the Three Gorges before impoundment,which are consistent with the distribution characteristics of contemporaneous flowing gravity field abnormality in this area.On this basis,we compared the equivalent stress field changes after the impoundment with the Hujiaping MS4.1 earthquake,and found that this earthquake occurred in the gradient zone between the increasing zone and decreasing zone of the equivalent stress.We analyzed that the equivalent stress varied distinctly in the gradient zone,where the stress and strain was accumulated and tectonic activity was intense.In addition,the gradient zone is located in the north section of the Xiannushan Fault,which is easy to make fault instable and move to induce the seismic activity.",
        "keywords": [
            "finite element",
            "gradient zone",
            "numerical simulation",
            "equivalent stress field",
            "Three Gorges Reservoir"
        ],
        "authors": [
            {
                "name": "WU Jian-chao",
                "org": "Institute of Seismology,CEA,Wuhan ,Hubei,China;Institute of Earthquake Engineering in Wuhan,Wuhan ,Hubei,China"
            },
            {
                "name": "CHEN Shu-jun",
                "org": "Institute of Seismology,CEA,Wuhan ,Hubei,China;Institute of Earthquake Engineering in Wuhan,Wuhan ,Hubei,China"
            },
            {
                "name": "CAI Yong-jian",
                "org": "Institute of Seismology,CEA,Wuhan ,Hubei,China;Institute of Earthquake Engineering in Wuhan,Wuhan ,Hubei,China"
            },
            {
                "name": "LI Heng",
                "org": "Institute of Seismology,CEA,Wuhan ,Hubei,China;Institute of Earthquake Engineering in Wuhan,Wuhan ,Hubei,China"
            },
            {
                "name": "LEI Dong-ning",
                "org": "Institute of Seismology,CEA,Wuhan ,Hubei,China;Institute of Earthquake Engineering in Wuhan,Wuhan ,Hubei,China"
            },
            {
                "name": "YU Song",
                "org": "Institute of Seismology,CEA,Wuhan ,Hubei,China;Institute of Earthquake Engineering in Wuhan,Wuhan ,Hubei,China"
            },
            {
                "name": "QIAO Yue-qiang",
                "org": "Institute of Seismology,CEA,Wuhan ,Hubei,China;Institute of Earthquake Engineering in Wuhan,Wuhan ,Hubei,China"
            },
            {
                "name": "CHEN Zi-hua",
                "org": "Institute of Seismology,CEA,Wuhan ,Hubei,China"
            },
            {
                "name": "LIU Fan-zhen",
                "org": "Group 607 in Nonferrous Metals Geological Exploration Bureau of Jilin Province,Changchun ,Jilin,China"
            }
        ],
        "venue": "Journal of Seismological Research",
        "year": 2012
    },
    "wRzu5Zum": {
        "id": "wRzu5Zum",
        "title": "Coseismic displacement caused by the 2008 great Wenchuan earthquake derived from various types of geodetic data",
        "abstract": "We analyze the coseismic surface displacement field produced by the 2008 Wenchuan(Mw7.9) earthquake using various geodetic data including GPS measurements,SAR images,in combination with other data such as leveling,gravity and near-field strong motion records.The GPS data come from resurveys on several high-precision GPS networks and a triangulation network.Coseismic displacements at GPS sites are estimated to within 2 cm and triangulation points within 6~8 cm in precision.Two kinds of SAR data are used in the paper,including light-of-sight SAR interferograms with a precision better than 8 cm and three-dimensional surface displacements using SAR sub-pixel correlation to within 0.5 meters in precision.The coseismic displacements constructed by various types of data are characterized by the deformation pattern of a coherent motion of the footwall and anticlockwise rotation of the hanging wall.Site horizontal offsets in the Sichuan Basin are found to direct toward to the epicenter.Otherwise,the GPS sites in Wenchuan,Lixian and Maoxian along the Longmen Shan moved normal to the surface rupture as well.However,the GPS sites in Pingwu and Qingchuan were displaced initially parallel to and finally away from the rupture zone,in consistent with the rupture mechanism of thrusting-slip and right lateral strike-slip faulting.Whereas the hanging wall was uplifted significantly,the subsidence in the footwall was localized near the rupture zone.The far-field uplift in the Sichuan Basin is found with a hinge line(separating uplift from subsidence) parallel to the Longquan Shan fault.Finally,we test seismological slip models by fitting the coseismic displacement field,from which a mean misfit of 40~50 cm is derived for the GPS sites within 50 km to the rupture zone,and 5 cm for ones in the far-field.",
        "keywords": [
            "Wenchuan earthquake",
            "Geodesy",
            "Coseismic displacement field"
        ],
        "authors": [
            {
                "name": "YANG Shao-Min",
                "org": ",WANG Qi2 1 Key Laboratory of Earthquake Geodesy,Institute of Seismology,China Earthquake Administration,Wuhan ,China 2 Institute of Geophysics & Geomatics,Planetary Science Institute,China University of Geosciences,Wuhan ,China 3 First Institution of Survey Engineering,Sichuan Administration of Surveying Mapping & Geoinformation,Chengdu ,China 4 Second Monitoring Center,China Earthquake Administration,Xi'an ,China 5 Institute of Hazard Mitigation and Life Assistance,Sichuan Earthquake Administration,Chengdu ,China"
            },
            {
                "name": "LAN Qi-Gui",
                "org": ",WANG Qi2 1 Key Laboratory of Earthquake Geodesy,Institute of Seismology,China Earthquake Administration,Wuhan ,China 2 Institute of Geophysics & Geomatics,Planetary Science Institute,China University of Geosciences,Wuhan ,China 3 First Institution of Survey Engineering,Sichuan Administration of Surveying Mapping & Geoinformation,Chengdu ,China 4 Second Monitoring Center,China Earthquake Administration,Xi'an ,China 5 Institute of Hazard Mitigation and Life Assistance,Sichuan Earthquake Administration,Chengdu ,China"
            },
            {
                "name": "NIE Zhao-Sheng",
                "org": ",WANG Qi2 1 Key Laboratory of Earthquake Geodesy,Institute of Seismology,China Earthquake Administration,Wuhan ,China 2 Institute of Geophysics & Geomatics,Planetary Science Institute,China University of Geosciences,Wuhan ,China 3 First Institution of Survey Engineering,Sichuan Administration of Surveying Mapping & Geoinformation,Chengdu ,China 4 Second Monitoring Center,China Earthquake Administration,Xi'an ,China 5 Institute of Hazard Mitigation and Life Assistance,Sichuan Earthquake Administration,Chengdu ,China"
            },
            {
                "name": "WANG Qing-Liang",
                "org": ",WANG Qi2 1 Key Laboratory of Earthquake Geodesy,Institute of Seismology,China Earthquake Administration,Wuhan ,China 2 Institute of Geophysics & Geomatics,Planetary Science Institute,China University of Geosciences,Wuhan ,China 3 First Institution of Survey Engineering,Sichuan Administration of Surveying Mapping & Geoinformation,Chengdu ,China 4 Second Monitoring Center,China Earthquake Administration,Xi'an ,China 5 Institute of Hazard Mitigation and Life Assistance,Sichuan Earthquake Administration,Chengdu ,China"
            },
            {
                "name": "LI Heng",
                "org": ",WANG Qi2 1 Key Laboratory of Earthquake Geodesy,Institute of Seismology,China Earthquake Administration,Wuhan ,China 2 Institute of Geophysics & Geomatics,Planetary Science Institute,China University of Geosciences,Wuhan ,China 3 First Institution of Survey Engineering,Sichuan Administration of Surveying Mapping & Geoinformation,Chengdu ,China 4 Second Monitoring Center,China Earthquake Administration,Xi'an ,China 5 Institute of Hazard Mitigation and Life Assistance,Sichuan Earthquake Administration,Chengdu ,China"
            },
            {
                "name": "LIAO Hua",
                "org": ",WANG Qi2 1 Key Laboratory of Earthquake Geodesy,Institute of Seismology,China Earthquake Administration,Wuhan ,China 2 Institute of Geophysics & Geomatics,Planetary Science Institute,China University of Geosciences,Wuhan ,China 3 First Institution of Survey Engineering,Sichuan Administration of Surveying Mapping & Geoinformation,Chengdu ,China 4 Second Monitoring Center,China Earthquake Administration,Xi'an ,China 5 Institute of Hazard Mitigation and Life Assistance,Sichuan Earthquake Administration,Chengdu ,China"
            },
            {
                "name": "TAN Kai",
                "org": ",WANG Qi2 1 Key Laboratory of Earthquake Geodesy,Institute of Seismology,China Earthquake Administration,Wuhan ,China 2 Institute of Geophysics & Geomatics,Planetary Science Institute,China University of Geosciences,Wuhan ,China 3 First Institution of Survey Engineering,Sichuan Administration of Surveying Mapping & Geoinformation,Chengdu ,China 4 Second Monitoring Center,China Earthquake Administration,Xi'an ,China 5 Institute of Hazard Mitigation and Life Assistance,Sichuan Earthquake Administration,Chengdu ,China"
            },
            {
                "name": "QIAO Xue-Jun",
                "org": ",WANG Qi2 1 Key Laboratory of Earthquake Geodesy,Institute of Seismology,China Earthquake Administration,Wuhan ,China 2 Institute of Geophysics & Geomatics,Planetary Science Institute,China University of Geosciences,Wuhan ,China 3 First Institution of Survey Engineering,Sichuan Administration of Surveying Mapping & Geoinformation,Chengdu ,China 4 Second Monitoring Center,China Earthquake Administration,Xi'an ,China 5 Institute of Hazard Mitigation and Life Assistance,Sichuan Earthquake Administration,Chengdu ,China"
            },
            {
                "name": "WANG Qi",
                "org": ",WANG Qi2 1 Key Laboratory of Earthquake Geodesy,Institute of Seismology,China Earthquake Administration,Wuhan ,China 2 Institute of Geophysics & Geomatics,Planetary Science Institute,China University of Geosciences,Wuhan ,China 3 First Institution of Survey Engineering,Sichuan Administration of Surveying Mapping & Geoinformation,Chengdu ,China 4 Second Monitoring Center,China Earthquake Administration,Xi'an ,China 5 Institute of Hazard Mitigation and Life Assistance,Sichuan Earthquake Administration,Chengdu ,China"
            }
        ],
        "venue": "Chinese Journal of Geophysics",
        "year": 2012
    },
    "WFnbcuV0": {
        "id": "WFnbcuV0",
        "title": "ON SEISMOGENIC AND ITS BACKGROUND TECTONICS OF JIUJIANG-RUICHANG SEISMIC SEQUENCE",
        "abstract": "Through a variety of means,such as remote sensing,distribution of aftershock and field exploration,it is proved that in the north to Ruichang there is a group of NNW fault\u2014\u2014Wushan buried fault which dissecting through the upper crust at least and then it is proposed that the Jiujiang-ruichang earthquake may result from the NE Ruichang-Wuning fault together with the Wushan buried fault,concretely,the mainshock is controled by the former and the aftershock by the later.",
        "keywords": [
            "tectonic background",
            "seismic sequence",
            "Ruichang-Wuning fault",
            "Wushan buried fault",
            "Jiujiang-Ruichang earthquake"
        ],
        "authors": [
            {
                "name": "Wang Dun",
                "org": "Institute of Seismology,CEA,Wuhan "
            },
            {
                "name": "Xiao Heping",
                "org": "Earthquake Administration of Hunan Province,Changsha "
            },
            {
                "name": "Yao Yunsheng",
                "org": "Institute of Seismology,CEA,Wuhan "
            },
            {
                "name": "Song Chen",
                "org": "Institute of Seismology,CEA,Wuhan "
            },
            {
                "name": "Li Heng",
                "org": "Institute of Seismology,CEA,Wuhan "
            }
        ],
        "venue": "Journal of Geodesy and Geodynamics",
        "year": 2007
    },
    "aRPjxUoJ": {
        "id": "aRPjxUoJ",
        "title": "Analytic Solutions and Their Errors of Groundwater Phreatic Line in Bank Slope under Reservoir Water Level Fluctuation",
        "abstract": "Although analytical method is a practical method in the calculation of phreatic line of groundwater in reservoir bank slope,it is based on certain assumptions and the linearization of the Boussinesq's equation.Different mathematical models for the seepage of groundwater were established and then solved by analytical method or finite element method.By comparing the solutions to these different models,the errors caused by these assumptions and the linearization were analyzed.Results showed that both the errors caused by the linearization and the neglect of unsaturated seepage were greater than the error caused by assuming the reservoir bank is vertical,and all of them decreased with the increase of permeability coefficient.The error caused by the assumption of uniform water level changes could be ignored in the case of Three Gorges reservoir water scheduling.When calculating the groundwater phreatic line in reservoir bank slope,analytical method only applies to the case when the water level fluctuation amplitude is smaller than 30% of the aquifer thickness,the geotechnical structure is regular,and the soil has good permeability and simple structure.",
        "keywords": [
            "analytical solution",
            "error",
            "application scopes",
            "bank slope",
            "phreatic line",
            "reservoir water level fluctuation"
        ],
        "authors": [
            {
                "name": "HU Qing",
                "org": "Key Laboratory of Earthquake Geodesy,Institute of Seismology,CEA,Wuhan ,China;Wuhan Institute of Earthquake Engineering,Wuhan ,China"
            },
            {
                "name": "LI Yi",
                "org": "Hubei Electric Power Survey and Design Institute,Wuhan ,China"
            },
            {
                "name": "LI Heng",
                "org": "Key Laboratory of Earthquake Geodesy,Institute of Seismology,CEA,Wuhan ,China;Wuhan Institute of Earthquake Engineering,Wuhan ,China"
            },
            {
                "name": "HU Kai-feng",
                "org": "Key Laboratory of Earthquake Geodesy,Institute of Seismology,CEA,Wuhan ,China;Wuhan Institute of Earthquake Engineering,Wuhan ,China"
            },
            {
                "name": "ZHENG De-bin",
                "org": "Key Laboratory of Earthquake Geodesy,Institute of Seismology,CEA,Wuhan ,China;Wuhan Institute of Earthquake Engineering,Wuhan ,China"
            }
        ],
        "venue": "Journal of Yangtze River Scientific Research Institute",
        "year": 2013
    },
    "gCTX5BoL": {
        "id": "gCTX5BoL",
        "title": "Long-period seismic design spectra in Hankou area",
        "abstract": "In this paper,102 strong ground motion acceleration records are used to calculate the average acceleration response spectra.According to the basic forms and characteristics of the average spectrum of strong motion records,the seismic design response spectra in long-period for flexible structures are established.In order to select representative strong ground motion records,the following factors are considered:1) seismic geological environment of Hankou and site soil condition;2) the reliability of strong ground motion records in long-period phase;3) influence to long-period response spectra of potential earthquakes with different magnitudes.",
        "keywords": [
            "long-period response spectra",
            "site condition",
            "seismic geological environment",
            "strong ground motion",
            "aseismatic design"
        ],
        "authors": [
            {
                "name": "LI Heng",
                "org": "Institute of Seismology,China Earthquake Administration,Wuhan ,China;Wuhan Institute of Earthquake Engineering,Wuhan ,China"
            },
            {
                "name": "FENG Qian",
                "org": "Institute of Seismology,China Earthquake Administration,Wuhan ,China;Wuhan Institute of Earthquake Engineering,Wuhan ,China"
            },
            {
                "name": "CAI Yongjian",
                "org": "Institute of Seismology,China Earthquake Administration,Wuhan ,China;Wuhan Institute of Earthquake Engineering,Wuhan ,China"
            },
            {
                "name": "ZHENG Shuiming",
                "org": "Institute of Seismology,China Earthquake Administration,Wuhan ,China;Wuhan Institute of Earthquake Engineering,Wuhan ,China"
            },
            {
                "name": "LEI Dongning",
                "org": "Institute of Seismology,China Earthquake Administration,Wuhan ,China;Wuhan Institute of Earthquake Engineering,Wuhan ,China"
            }
        ],
        "venue": "Engineering Journal of Wuhan University",
        "year": 2011
    },
    "l9uWwAo7": {
        "id": "l9uWwAo7",
        "title": "The earthquake disaster characteristic and cause discussion about Hanyuan abnormal intensity from the 2008 Wenchuan M8.0 earthquake",
        "abstract": "",
        "keywords": [
            "earthquake disaster characteristic",
            "The 2008 Wenchuan M8.0 earthquake",
            "Hanyuan abnormal intensity",
            "site condition",
            "building destroy"
        ],
        "authors": [
            {
                "name": "LEI Dong-ning",
                "org": "Institute of Seismology,China Earthquake Administration,Hubei Wuhan ;Institute of Earthquake Engineering,Hubei Wuhan "
            },
            {
                "name": "CAI Yong-jian",
                "org": "Institute of Seismology,China Earthquake Administration,Hubei Wuhan ;Institute of Earthquake Engineering,Hubei Wuhan ;Faculty of Earth Science,China University of Geosciences,Hubei Wuhan ,China"
            },
            {
                "name": "LI Heng",
                "org": "Institute of Seismology,China Earthquake Administration,Hubei Wuhan ;Institute of Earthquake Engineering,Hubei Wuhan "
            },
            {
                "name": "CHEN Shu-jun",
                "org": "Institute of Seismology,China Earthquake Administration,Hubei Wuhan ;Institute of Earthquake Engineering,Hubei Wuhan "
            }
        ],
        "venue": "Earthquake Research in Sichuan",
        "year": 2011
    },
    "SvAiOnhF": {
        "id": "SvAiOnhF",
        "title": "ACTIVITY FEATURE AND SLIP RATE OF MIDDLE SEGMENT OF ENSHI FAULT IN QUATERNARY",
        "abstract": "On the basis of detailed geomorphologic analysis of faulting profiles and deformed alluvial fans,etc.we suggest that the Enshi fault had been intensely active in Quaternary,it is characterized by dominant dip-slip and partly dextral movement component and the displacement of the proluvium fans developed at the valley mouth of a gully.The samples collected from the top of the proluvium fans were dated by Thermo luminescence to be 197.18\u00b116.76 B.P.to 33.33\u00b12.83 B.P.The horizontal slip rate of the middle segment of Enshi fault is determined to be 0.43-0.5 mm/a,and the vertical slip rate is determined to be 0.07-0.17 mm/a.",
        "keywords": [
            "Quaternary",
            "proluvium fan",
            "Enshi fault",
            "slip rate",
            "tectonic landforms"
        ],
        "authors": [
            {
                "name": "Cai Yongjian",
                "org": "%%#Institute of Seismology,CEA,Wuhan 2)Institute of Earthquake Engineering of Wuhan,Wuhan 3)College of Earth Science,China University of Geosciences,Wuhan )"
            },
            {
                "name": "Lei Dongning",
                "org": "%%#Institute of Seismology,CEA,Wuhan 2)Institute of Earthquake Engineering of Wuhan,Wuhan 3)College of Earth Science,China University of Geosciences,Wuhan )"
            },
            {
                "name": "Li Heng",
                "org": "%%#Institute of Seismology,CEA,Wuhan 2)Institute of Earthquake Engineering of Wuhan,Wuhan 3)College of Earth Science,China University of Geosciences,Wuhan )"
            },
            {
                "name": "Qiao Yueqiang",
                "org": "%%#Institute of Seismology,CEA,Wuhan 2)Institute of Earthquake Engineering of Wuhan,Wuhan 3)College of Earth Science,China University of Geosciences,Wuhan )"
            },
            {
                "name": "Wu Jianchao",
                "org": "%%#Institute of Seismology,CEA,Wuhan 2)Institute of Earthquake Engineering of Wuhan,Wuhan 3)College of Earth Science,China University of Geosciences,Wuhan )"
            }
        ],
        "venue": "Journal of Geodesy and Geodynamics",
        "year": 2011
    },
    "h5pqPfco": {
        "id": "h5pqPfco",
        "title": "Seismic design spectra in long-period from spectral displacement analyses",
        "abstract": "The effect of the long-period filter cut-off,Tc,on spectral displacements is analysed using the NGA database of the Pacific Earthquake Engineering Research Center.Long-period spectral displacements would be suppressed badly,if a short Tc is chosen.Strong ground motion accelerograms with reliable period up to at least 10s are selected to investigate the characteristics of displacement response spectra at long periods.The results indicate that the period,in which the spectral displacement culminates,is a significant parameter to control long-period spectral ordinates.This parameter can't be affected obviously by site condition and magnitude,but greatly depends on epicentral distance with linear relation.The maximum amplification factor of displacement spectrum fluctuates slightly,and can be treated as a constant.A transition region is suggested to insert between velocity-sensitive region and displacement-sensitive region to fit for displacement spectrum,and the values of some parameters are proposed in this paper.",
        "keywords": [
            "amplification factor",
            "long-period filter cut-off",
            "epicentral distance",
            "spectral displacement",
            "long period"
        ],
        "authors": [
            {
                "name": "LI Heng",
                "org": "Key Laboratory of Earthquake Geoodesy,Institute of Seismology,China Earthquake Administration,Wuhan ,China;Wuhan Institute of Earthquake Engineering,Wuhan ,China"
            },
            {
                "name": "LI Longan",
                "org": "China Zhongtie Major Bridge Reconnaissance & Design Institute Co.,Ltd.,Wuhan ,China"
            },
            {
                "name": "FENG Qian",
                "org": "Key Laboratory of Earthquake Geoodesy,Institute of Seismology,China Earthquake Administration,Wuhan ,China;Wuhan Institute of Earthquake Engineering,Wuhan ,China"
            }
        ],
        "venue": "Journal of Earthquake Engineering and Engineering Vibration",
        "year": 2012
    },
    "3FYhFqT8": {
        "id": "3FYhFqT8",
        "title": "GIS AND NUMERICAL SIMULATION TECHNIQUES BASED RISK ASSESSMENT OF INDUCED EARTHQUAKE IN THREE-GORGE RESERVOIR HEAD AREA",
        "abstract": "GIS and numerical simulation techniques are used to quantitative risk assessment of induced earthquake in the Three-Gorge reservoir head area.The technical route is that the simulation model is set up through the analysis of affecting factors.The simulation result is obtained with FLAC 3D.The assessment database is set up by the result of simulation and monitoring data.Each unit is estimated with the maximum tensile strain criterion for judging rock tensile failure and the Mohr-Coulomb criterion for judging rock shear failure.The unit is further estimated by comparing the first principal stress,the third principal stress and the displacement where the induced earthquake had taken place after impounding of the reservoir on a GIS platform.The result shows that building database containing various data based on the same GIS platform is the basement of integrated factor model.The result of risk assessment possesses the reliability in the Three-Gorges reservoir head area.The simulation result is also calculated with the earthquake model and the calculated result is further modified with the monitored data.",
        "keywords": [
            "Risk assessment",
            "Reservoir",
            "Numerical simulation",
            "Induced earthquake",
            "GIS"
        ],
        "authors": [
            {
                "name": "LI Xueping",
                "org": "Engineering Research Center of Rock-Soil Drilling & Excavation and Protection,Ministry of Education,Wuhan ;Engineering Faculty,China University of Geosciences,Wuhan "
            },
            {
                "name": "WANG Yang",
                "org": "Engineering Faculty,China University of Geosciences,Wuhan "
            },
            {
                "name": "LI Heng",
                "org": "Institute of Seismology,CEA,Wuhan "
            }
        ],
        "venue": "Journal of Engineering Geology",
        "year": 2010
    },
    "l1JVOUet": {
        "id": "l1JVOUet",
        "title": "DISCUSSION ON TWO PROBLEMS IN EARTHQUAKE LOSS ANALYSIS",
        "abstract": "Two problems in earthquake lose analysis,i.e.,how to work out the formula of intensity attenuation which is suitable for earthquake loss analysis and how to estimate the indirect economic loss at the macroscopic economical scale are discussed.",
        "keywords": [
            "indirect economic loss",
            "intensity attenuation",
            "productive capacity",
            "earthquake loss",
            "epicentral intensity"
        ],
        "authors": [
            {
                "name": "Li Heng",
                "org": "%%#Institute of Seismology,CEA,Wuhan 2)Crustal Movement Laboratory,Wuhan 3)Wuhan Institute of Earthquake Engineering,Wuhan )"
            },
            {
                "name": "Yao Yunsheng",
                "org": "%%#Institute of Seismology,CEA,Wuhan 2)Crustal Movement Laboratory,Wuhan 3)Wuhan Institute of Earthquake Engineering,Wuhan )"
            },
            {
                "name": "Chen Shujun",
                "org": "%%#Institute of Seismology,CEA,Wuhan 2)Crustal Movement Laboratory,Wuhan 3)Wuhan Institute of Earthquake Engineering,Wuhan )"
            }
        ],
        "venue": "Journal of Geodesy and Geodynamics",
        "year": 2007
    },
    "jtXKC4pz": {
        "id": "jtXKC4pz",
        "title": "Application of\"cocktail wine\"in pain relief after total knee arthroplasty",
        "abstract": "BACKGROUND:\"Cocktail wine\" therapy is a new way for pain relief after total knee arthroplasty with fewer side effects.OBJECTIVE:To observe the early efficacy of postoperative periarticular injection of multimodal analgesia(\"cocktail wine\" treatment) after total knee arthroplasty.METHODS:Twenty-six patients undergoing unilateral total knee arthroplasty had the same treatment of pain relief perioperatively.All the cases were injected with the \"cocktail wine\" intraoperatively.The postoperative visual analogue scale(VAS) of pain,the range of motion of knee joint and wound complications were analyzed versus the preoperative data.RESULTS AND CONCLUSION:All the patients did not take the medicine of parenteral opiods,and there were significant improvement in pain VAS during rest and exercise for 1-3 days postoperatively.Time for active straight leg lifting was 2.5 days postoperatively in average.During the 2nd and 3rd days postoperatively,the average knee joint activities were 45\u00b0 and 55\u00b0,and no wound complications occurred.These demonstrated that the periarticular injection of analgesia can reduce the scores of the VAS during rest and exercise and improve the activity of knee joints in the early stage,and it is simple,practical,safe and effective.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Li Heng",
                "org": "Department of Orthopedics,Fifth Affiliated Hospital of Qiqihar Medical University,Daqing Oilfield General Hospital Group LongNan Hospital,Daqing ,Heilongjiang Province,China"
            },
            {
                "name": "Sui Fu-ge",
                "org": "Department of Orthopedics,Fifth Affiliated Hospital of Qiqihar Medical University,Daqing Oilfield General Hospital Group LongNan Hospital,Daqing ,Heilongjiang Province,China"
            },
            {
                "name": "Zhang Ning-ning",
                "org": "Department of Orthopedics,Fifth Affiliated Hospital of Qiqihar Medical University,Daqing Oilfield General Hospital Group LongNan Hospital,Daqing ,Heilongjiang Province,China"
            },
            {
                "name": "Wang Qun",
                "org": "Department of Orthopedics,Fifth Affiliated Hospital of Qiqihar Medical University,Daqing Oilfield General Hospital Group LongNan Hospital,Daqing ,Heilongjiang Province,China"
            },
            {
                "name": "Wang Dong-jun",
                "org": "Department of Orthopedics,Fifth Affiliated Hospital of Qiqihar Medical University,Daqing Oilfield General Hospital Group LongNan Hospital,Daqing ,Heilongjiang Province,China"
            },
            {
                "name": "Wang Qiang",
                "org": "Department of Orthopedics,Fifth Affiliated Hospital of Qiqihar Medical University,Daqing Oilfield General Hospital Group LongNan Hospital,Daqing ,Heilongjiang Province,China"
            },
            {
                "name": "Xiaofeng He",
                "org": "The Fifth Hospital Affiliated to Qiqihar Medical University(The Fifth Hospital Affiliated to Qiqihar Medical University,Fifth Affiliated Hospital of Qiqihar Medical University (Longnan Hospital of Daqing City),The Fifth Affiliated Hospital of Qiqihar Medical University,Fifth Affiliated Hospital of Qiqihar Medical University),,China"
            }
        ],
        "venue": "Journal of Clinical Rehabilitative Tissue Engineering Research",
        "year": 2011
    },
    "v8MQ189W": {
        "id": "v8MQ189W",
        "title": "Percutaneous bone cement vertebroplasty in treating senile osteoporotic compression fractures of the vertebra",
        "abstract": "AIM: To evaluate the therapeutic effects of percutaneous bone cement (polymethyl methacrylate) vertebroplasty in the treatment of osteoporotic compression fractures. METHODS: Thirty-five patients (40 vertebra) with vertebral osteoporotic compression fractures were treated with percutaneous polymethylmethacrylate vertebroplasty in Department of Orthopedics,China-Japan Union Hospital of Jilin University,and Daqing Longnan Hospital. The cement was product of KYPHON (U.S. No. GB/T19001-2000 and YY/T0287-1996). RESULTS: All the 35 patients were followed up for 6 months. None of them experienced cement extravasation,injury of spinal cord and nerve roots or other severe complications after treatment. Among the 35 cases,5 had pains in puncture sites,and relieved by painkiller; 25 (71.4%) had complete relief,8 (22.6) were significantly relieved,2 (6.0%) were mildly relieved,and 0 had no relief. Moreover,15 cases could get up and move within 72 hours after the surgery. No further vertebral compressions or pains reoccurred postoperatively. CONCLUSION: Percutaneous polymethylmethacrylate vertebroplasty can effectively improve the pain in patients with osteoporotic compression fractures of vertebra. During the 6 months follow-up,no adverse host response in filler is found,and the clinical effect is good.",
        "keywords": [],
        "authors": [
            {
                "name": "Jing YH",
                "org": ""
            },
            {
                "name": "Yang XY",
                "org": ""
            },
            {
                "name": "Zhao CR",
                "org": ""
            },
            {
                "name": "Li H",
                "org": ""
            },
            {
                "name": "Guo MF",
                "org": ""
            },
            {
                "name": "Wang Q",
                "org": ""
            },
            {
                "name": "Wang Q",
                "org": ""
            }
        ],
        "venue": "Journal of Clinical Rehabilitative Tissue Engineering Research",
        "year": 2007
    },
    "iVxleKDh": {
        "id": "iVxleKDh",
        "title": "Expression of serum interleukin-6,8,10,C-reactive protein and deep vein thrombosis after joint replacement",
        "abstract": "BACKGROUND:Vascular endothelial cell injury,slow blood flow,hypercoagulability,and abnormal white blood cell rheology are the important factors for deep vein thrombosis after joint replacement.OBJECTIVE:To analyze the association of serum interleukin 6,8,10,C-reactive protein expression with deep vein thrombosis after joint replacement.METHODS:Serum interleukin 6,8,10,C-reactive protein expression were detected 68 cases of joint replacement patients before and after replacement,and ultrasonic testing was used to determine whether deep vein thrombosis occurred.RESULTS AND CONCLUSION:The expression of serum interleukin 6,8,10,C-reactive protein in thrombosis patients after joint replacement was higher than that of patients without thrombosis after joint replacement at 1 and 3 days (P<0.05),indicating inflammatory factors participated in thrombosis formation.Real-time monitoring of changes in these indicators could help to prevent thrombosis.In the patients with thrombosis,the levels of serum interleukin 6,8,10,C-reactive protein were higher at 1 and 3 days after joint replacement than before joint replacement (P<0.05);however,at 5 days after joint replacement,the levels of these indicators were close to those before joint replacement (P> 0.05).After joint replacement,the blood hypercoagulability had a gradual reduction process,especially at 3 days after joint replacement that was a key to anti-inflammatory anticoagulant treatment.",
        "keywords": [],
        "authors": [
            {
                "name": "Yang Feng",
                "org": " Fourth Ward,Department of Orthopedics,Longnan Hospital of Daqing,Daqing ,Heilongjiang Province,China"
            },
            {
                "name": "Sui Fu-ge",
                "org": " Fourth Ward,Department of Orthopedics,Longnan Hospital of Daqing,Daqing ,Heilongjiang Province,China"
            },
            {
                "name": "Zhang Yong",
                "org": " Fourth Ward,Department of Orthopedics,Longnan Hospital of Daqing,Daqing ,Heilongjiang Province,China"
            },
            {
                "name": "Li Heng",
                "org": " Fourth Ward,Department of Orthopedics,Longnan Hospital of Daqing,Daqing ,Heilongjiang Province,China"
            },
            {
                "name": "Ma Dong-sheng",
                "org": " Fourth Ward,Department of Orthopedics,Longnan Hospital of Daqing,Daqing ,Heilongjiang Province,China"
            },
            {
                "name": "Li Qiang",
                "org": " Fourth Ward,Department of Orthopedics,Longnan Hospital of Daqing,Daqing ,Heilongjiang Province,China"
            },
            {
                "name": "Tian Fei-peng",
                "org": " Fourth Ward,Department of Orthopedics,Longnan Hospital of Daqing,Daqing ,Heilongjiang Province,China"
            }
        ],
        "venue": "Journal of Clinical Rehabilitative Tissue Engineering Research",
        "year": 2011
    },
    "waUjG0mu": {
        "id": "waUjG0mu",
        "title": "Lumbar instability following intervertebral tamped bone transplantation and screw internal fixation",
        "abstract": "The aim of this study is to investigate the effect of intervertebral tamped bone particles transplantation and screw internal fixation system on treating degenerative lumbar instability syndrome. Sixty-eight patients diagnosed as degenerative lumber instability syndrome, including 46 males and 22 females, were enrolled from the Department of Orthopaedics in Daqing Longnan Hospital and the Department of Orthopaedics in China-Japan Union Hospital of Jilin University between June 2005 and June 2007. They were treated by means of not only the whole laminectomy and nerve root canal widening, but also posterior intervertebral tamped bone particles transplantation and pedicle screw internal fixation. All of 68 patients were followed up for more than 6 months. According to JOA Grade Criterion, these patients on admission were evaluated as excellent in 48 cases, good in 12 cases, fair in 6 cases and bad in 2 cases. The rate of excellent and good outcomes was 95.3%. The 100% rate of spinal fusion with intervertebral tamped bone particles transplantation and pedicle screw internal fixation was achieved at month 6 postoperation by the evidence of lumbar CR radiographs. The fused segments were all stable, neither bone particles nor implant materials show biocompatibility to the host.",
        "keywords": [],
        "authors": [
            {
                "name": "Jing Yuan-hai",
                "org": "Department of Orthopaedics, Daqing Longnan Hospital, Daqing , Heilongjiang Province, China"
            },
            {
                "name": "Nie Chang-chun",
                "org": "Department of Orthopaedics, Daqing Longnan Hospital, Daqing , Heilongjiang Province, China"
            },
            {
                "name": "Zhou Ji-hui",
                "org": "Department of Orthopaedics, Daqing Longnan Hospital, Daqing , Heilongjiang Province, China"
            },
            {
                "name": "Fan Hong-yuan",
                "org": "Department of Orthopaedics, Daqing Longnan Hospital, Daqing , Heilongjiang Province, China"
            },
            {
                "name": "Zhao Cong-ran",
                "org": "Department of Orthopaedics, Daqing Longnan Hospital, Daqing , Heilongjiang Province, China"
            },
            {
                "name": "Li Heng",
                "org": "Department of Orthopaedics, Daqing Longnan Hospital, Daqing , Heilongjiang Province, China"
            },
            {
                "name": "Guo Ming-feng",
                "org": "Department of Orthopaedics, Daqing Longnan Hospital, Daqing , Heilongjiang Province, China"
            },
            {
                "name": "Zhu Qing-san",
                "org": "Department of Orthopaedics, China-Japan Union Hospital of Jilin University, Changchun , Jilin Province, China"
            },
            {
                "name": "Yang Xiao-yu",
                "org": "Department of Orthopaedics, China-Japan Union Hospital of Jilin University, Changchun , Jilin Province, China"
            }
        ],
        "venue": "Journal of Clinical Rehabilitative Tissue Engineering Research",
        "year": 2008
    },
    "Ja9DLJhn": {
        "id": "Ja9DLJhn",
        "title": "Analysis of complications of kyphoplasty for osteoporotic vertebral compression fractures",
        "abstract": "Objectives: To Summarize the complications of percutaneous kyphoplasty(PKP) for osteoporotic vertebral compression fractures(OVCFs),and to investigate its causes and prevention.Methods: From September 2004 to June 2009,the PKP was performed on 115 OVCFs patients.There were 24 males and 91 females,with an average age of 68 years(range,52-83 years).83 cases had single vertebra,24 cases had double vertebrae,5 cases had 3 vertebrae,2 cases had 4 vertebrae,1 case had 5 vertebrae involved.Preoperative MRI STIR sequence was used to determine injured segment,including 1 in T6,2 in T7,2 in T8,8 in T9,9 in T10,24 in T11,44 in T12,41 in L1,18 in L2,5 in L3,3 in L4,2 in L5.The complications and causes were analyzed.Results: A total of 21 cases was noted complications,with the rate of occurrence of 18.2%.Bone cement leakage was noted in 13 cases(11.3%);intraoperative balloon rupture in 3 cases(2.6%);perforation into the spinal canal in 2 cases(1.7%);loss of height in 2 cases(1.7%);postoperative vertebral collapse 1 cases(0.9%).No severe neurological deficit,epidural hematoma or pulmonary embolism was noted.Conclusions: The complications associated with PKP treatment include bone cement leakage,balloon rupture,perforation into the spinal canal,vertebral height loss,postoperative vertebral collapse,which should be managed by corresponding preventions.",
        "keywords": [
            "Prevention",
            "Osteoporotic",
            "Complications",
            "Vertebral compression fractures",
            "Percutaneous vertebral kyphoplasty"
        ],
        "authors": [
            {
                "name": "SUI Fuge",
                "org": ",et al Department of Orthopaedics,Daqing Longnan Hospital,Daqing,,China"
            },
            {
                "name": "LI Heng",
                "org": ",et al Department of Orthopaedics,Daqing Longnan Hospital,Daqing,,China"
            },
            {
                "name": "ZHAO Congran",
                "org": ",et al Department of Orthopaedics,Daqing Longnan Hospital,Daqing,,China"
            }
        ],
        "venue": "Chinese Journal of Spine and Spinal Cord",
        "year": 2012
    },
    "KIdAkhP4": {
        "id": "KIdAkhP4",
        "title": "Unilateral percutaneous kyphoplasty for multi-level osteoporotic vertebral compression fractures with single balloon",
        "abstract": "Objective To investigate the clinical therapeutic effect of unilateral percutaneous kyphoplasty (PKP) for multi-level osteoporotic vertebral compression fractures (OVCF) with single balloon.Methods Twenty-five OVCF patients with a total of 60 vertebrae were treated by unilateral PKP with single balloon method.Post-operative pain relief and reduction of the fracture were observed,as well as the improvement of height of vertebral body and Cobb's angle were measured.Results All procedure were uneventful.The operation time was 30.4 min/vertebra in average,from 53 to 146 min.The balloon's expansion pressures were from 98 to 320 Psi with 183 Psi in average,expansion volume were 2-4.5 ml with 3.25 ml in average,expansion frequency were 2-6 times with 3.3 times in average.During the procedure,the balloon rupture occurred in 3 cases.The volume of cement injection were 2-5 ml,3.5 ml/vertebra in average.During the procedure,there were 2 cases with intraspinal leakage and 1 case with paraspinal leakage,which led to no obvious clinical symptoms at all.The VAS were decreased from 7.5 \u00b1 1.0 preoperatively to 3.2 \u00b1 0.7 postoperatively,vertebral body height and Cobb's angle were improved significantly (P <0.05).After 6-24 months' follow-up,all patients obtained steady maintenance of pain relief effects,and no surgical complication occurred.Conclusion Unilateral PKP with single balloon can be used to treat multi-level OVCF for its advantage of short operative time,low cost and satisfactory effects.",
        "keywords": [
            "Percutaneous kyphoplasty",
            "Spinal fractures",
            "Osteoporosis"
        ],
        "authors": [
            {
                "name": "SUI Fu-ge",
                "org": ".Department of Orthopaedics,Longnan Hospital of Daqing,Daqing,Heilongjiang ,China"
            },
            {
                "name": "ZHAO Cong-ran",
                "org": ".Department of Orthopaedics,Longnan Hospital of Daqing,Daqing,Heilongjiang ,China"
            },
            {
                "name": "LI Heng",
                "org": ".Department of Orthopaedics,Longnan Hospital of Daqing,Daqing,Heilongjiang ,China"
            },
            {
                "name": "WANG Qun",
                "org": ".Department of Orthopaedics,Longnan Hospital of Daqing,Daqing,Heilongjiang ,China"
            },
            {
                "name": "GUO Ming-feng",
                "org": ".Department of Orthopaedics,Longnan Hospital of Daqing,Daqing,Heilongjiang ,China"
            },
            {
                "name": "WANG Qiang",
                "org": ".Department of Orthopaedics,Longnan Hospital of Daqing,Daqing,Heilongjiang ,China"
            },
            {
                "name": "HE Xiao-feng",
                "org": ".Department of Orthopaedics,Longnan Hospital of Daqing,Daqing,Heilongjiang ,China"
            },
            {
                "name": "WANG Dong-jun",
                "org": ".Department of Orthopaedics,Longnan Hospital of Daqing,Daqing,Heilongjiang ,China"
            }
        ],
        "venue": "Chinese Journal of Clinical and Basic Orthopaedic Research",
        "year": 2010
    },
    "hLVHHkgJ": {
        "id": "hLVHHkgJ",
        "title": "Status of community prevention and treatment of oral diseases in primary school pupils in Shenzhen",
        "abstract": "Objective To understand the knowledge,attitude and behavior(KAP)of oral health and the caries status in pupils in Shenzhen City. Methods A random cluster sampling of pupils in two primary schoold of Shenzhen was conducted for a questionnaire survey of oral health in 2002. Results The caries rates were 65.25% and 37.42% in the pilot trial school and non-pilot trial school of 1~4 years age group. The rates of permanent teeth caries were 38.20% and 14.9% in pilot and non-pilot trial group of 5~6 years old ones,showing significant defference(P<0.05). Conclusions Oral health education be conducted in the primary school to protect the oral health of the pupils ..",
        "keywords": [
            "integrated control",
            "pupils",
            "health education",
            "the cross-section study",
            "oral disease",
            "attitudes",
            "psychology",
            "behaviour",
            "knowledge"
        ],
        "authors": [
            {
                "name": "LI Heng",
                "org": "Yantian District Center for Disease Control and Prevention,Shenzhen ,Guangdong,P. R.China"
            },
            {
                "name": "CAI Jun-yuan",
                "org": "Yantian District Center for Disease Control and Prevention,Shenzhen ,Guangdong,P. R.China"
            },
            {
                "name": "WU Jian",
                "org": "Yantian District Center for Disease Control and Prevention,Shenzhen ,Guangdong,P. R.China"
            }
        ],
        "venue": "China Tropical Medicine",
        "year": 2009
    },
    "eFRsCR81": {
        "id": "eFRsCR81",
        "title": "Research on non-marriage sexually behaviors among truck drivers.",
        "abstract": "Objective To investigate non-marriage sexually behaviors among truck drivers in some city.Methods Cluster sampling was used to the investigation.Results Most of the objectives had non-marriage sex behavior and the condom-use rate was very low.Conclusions Health education and behavior intervention should be applied to the population.",
        "keywords": [
            "Sexually behaviors",
            "Commercial sex",
            "Truck drivers"
        ],
        "authors": [
            {
                "name": "LI Heng",
                "org": ",et al.Center for Diseases Control and Prevention of Yantian District,Shenzhen,GuangDong Province ,China"
            },
            {
                "name": "XIE Jin-yao",
                "org": ",et al.Center for Diseases Control and Prevention of Yantian District,Shenzhen,GuangDong Province ,China"
            }
        ],
        "venue": "Henan Journal of Preventive Medicine",
        "year": 2008
    },
    "LlG68DYu": {
        "id": "LlG68DYu",
        "title": "Survey on Hepatitis B Vaccination and its Awareness Rate Among the Family Members of HBsAg-positive Women in Yantian District of Shenzhen",
        "abstract": "Objective To investigate the hepatitis B vaccination and its awareness rate among the family members of HBsAg-positive fertile women in Yantian District of Shenzhen,so as to provide reference for prevention and control of the high risk population of hepatitis B.Methods A randomized sampling was carried out in HBsAg-positive fertile women's families,and a questionnaire was designed for the investigation.Results Totally,120 HBsAg-positive fertile women and 285 family members,including 117 spouses and 168 children,were investigated.The complete immunization rate of hepatitis B vaccine in children was 97.0%,and the immunization rate of hepatitis B immune globulin was 83.3%.The immunization rate of hepatitis B vaccine in the male spouses of the HBsAg-positive women was 40.2%.For all the male and female spouses,the total awareness rate of hepatitis B was 69.29%.The awareness rates of the knowledge that hepatitis B could be sexually transmitted and it could be prevented by condoms were lower,49.4% and 40.1%,respectively.No significant difference was observed between male and female spouses in respect of the awareness rate about mother-to-child transmission and condoms' value in the prevention of hepatitis B(P>0.05).However,as to the other 7 questions investigated,the awareness rates in the HBsAg-positive women were significantly higher than those in their male spouses(P<0.05).64.1% of the spouses thought that their husbands or wives should be vaccinated.Conclusions In the HBsAg-positive fertile women's families in Yantian District of Shenzhen,the complete immunization rate of hepatitis B vaccine in children is high,while the immunization rate and its awareness rate are low in the male spouses.More attention should be paid to the propaganda and education of hepatitis B vaccination and related knowledge in the male spouses of the HBsAg-positive fertile women.",
        "keywords": [
            "Awareness rate",
            "High-risk population",
            "Hepatitis B vaccine",
            "Immunization"
        ],
        "authors": [
            {
                "name": "LI Da-lin",
                "org": "Yantian District Center for Disease Control and Prevention,Shenzhen ,Guangdong,China"
            },
            {
                "name": "LI Heng",
                "org": "Yantian District Center for Disease Control and Prevention,Shenzhen ,Guangdong,China"
            },
            {
                "name": "XIE Shu-xian",
                "org": "Yantian District Center for Disease Control and Prevention,Shenzhen ,Guangdong,China"
            }
        ],
        "venue": "Practical Preventive Medicine",
        "year": 2012
    },
    "DpxHgwwo": {
        "id": "DpxHgwwo",
        "title": "Subject The Investigation of Occupational Hazards of Trichloroethylene in Yantian Shenzhen",
        "abstract": "[Objective]To understand the condition of occupational hazards of trichloroethylene(TEC) in Yantian Shenzhen,and offer basis for preventing occupational poisioning that caused by trichloroethylene.[Methods]Carried on the special investigation to all of the enterprises that used TEC in Yantian in 2004.[Results]There were 28 enterprises used TEC before rectification,20 enterprises use TEC after that. The qualification rate of Permissible Concentration-Short Time Exposure(PC-STEL) of TEC is 58.6% in the enterprises that before rectification,which was significantly lower than in the control 86.8%(P<0.01).The physical examination rate of occupational health of worker is 57.1% before them being on duty,one on duty is 89.1%,and 58.9% before leaving the post,and non of them was checked out a suspected occupational disease patient.The training rate of administrator in enterprises is 100.0%,the worker training rate is 97.6%.[Conclusion]The occupational hazards of trichloroethylene in Yantian is relatively not so serious,The result of the special rectification to the enterprises who used TEC is obvious.",
        "keywords": [
            "Occupational hazards",
            "Trichloroethylene"
        ],
        "authors": [
            {
                "name": "JIANG Hai-qing",
                "org": "Yantian District Center for Disease Control and Prevention of Shenzhen City,Shenzhen,,Guangdong,China"
            },
            {
                "name": "LI Heng",
                "org": "Yantian District Center for Disease Control and Prevention of Shenzhen City,Shenzhen,,Guangdong,China"
            },
            {
                "name": "LIAN Guo-jian",
                "org": "Yantian District Center for Disease Control and Prevention of Shenzhen City,Shenzhen,,Guangdong,China"
            }
        ],
        "venue": "Preventive Medicine Tribune",
        "year": 2006
    },
    "uWsT5nEE": {
        "id": "uWsT5nEE",
        "title": "Survey of occupational harmfulness in plastics and rubber indutries in Shenzhen City",
        "abstract": "Objective To understand the characteristics of occupational injuries in plastics and rubber manufacturing enterprises in Shenzhen. Methods The 4 plastics and rubber manufacturing factories were randomly chosen and occupational injuries was surveyed by questionnaires survey. Results The morbidity rate of occupational injuries was 7.5% in 4 plastics and rubber manufacturing factories. Most injures concentrated at 9:00\uff5e10:00 AM and 5:00\uff5e6:00 PM. With the increasing of working years and enhancement of technical levels of the workers ,the incidence of occupational injuries decreased. Occupation injury occurrence was related with worker's disposition,mood and the conditions of security protection equipment. The top 4 injuries were heat or fire scald (30.2%),object blow injury (14.1%),tumbles/drops (10.7%),and machine injury (3.4%).The finger or the toe were the major body part injured (65.8%). Conclusion The occupational injuries became an important public health problem,so it is urgent to develop the injury prevention and control program.",
        "keywords": [
            "epidemiology",
            "influence factor",
            "occupational injury",
            "disease incidence",
            "plastics",
            "occupational health"
        ],
        "authors": [
            {
                "name": "LI Heng",
                "org": "1.Futian District Center for Disease Control and Prevention,Shenzhen ,Guangdong,P. R.China"
            },
            {
                "name": "LIAN Guo-jian",
                "org": "1.Futian District Center for Disease Control and Prevention,Shenzhen ,Guangdong,P. R.China"
            },
            {
                "name": "YING Hui",
                "org": "1.Futian District Center for Disease Control and Prevention,Shenzhen ,Guangdong,P. R.China"
            }
        ],
        "venue": "China Tropical Medicine",
        "year": 2009
    },
    "QonlbjbT": {
        "id": "QonlbjbT",
        "title": "Distributed formation control for a cooperative multi-agent system using potential function and extremum seeking algorithm",
        "abstract": "The formation control and communication optimization problem of a multi-agent system is considered in this article. A classical approach for the formation control problem is potential function method. With potential function, agents are kept a given separation distance with neighbors. Since communication quality will generally change due to the physical environment during formation, a given separation distance might not always be the desired communication distance. In this paper, a distributed scheme integrating potential function and extremum seeking algorithm is proposed to obtain the desired separation distance between neighboring agents in real-time. A comprehensive performance index related to the environment is presented first, capturing a trade-off between formation tasks and communication quality. Since it is difficult to predict the gradient of the performance in physical environments, an adaptive model-free extremum seeking algorithm is developed, which calls for no knowledge of the gradient of the performance. Then the desired separation distance can be obtained dynamically by maximizing the performance with extremum seeking algorithm. Simulation results demonstrate effectiveness of the proposed scheme.",
        "keywords": [
            "optimisation",
            "adaptive model-free extremum seeking algorithm",
            "communication distance",
            "cooperative multiagent system",
            "communication optimization problem",
            "physical environments",
            "formation tasks",
            "multi-robot systems",
            "distributed control",
            "distributed scheme",
            "separation distance",
            "adaptive control",
            "neighboring agents",
            "comprehensive performance index",
            "potential function method",
            "cooperative systems",
            "distributed formation control",
            "communication quality"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Jun Peng",
                "org": ""
            },
            {
                "name": "Jianming Xiao",
                "org": ""
            },
            {
                "name": "Feng Zhou",
                "org": ""
            },
            {
                "name": "Weirong Liu",
                "org": ""
            },
            {
                "name": "Jing Wang",
                "org": ""
            }
        ],
        "venue": "ROBIO",
        "year": 2012
    },
    "141Kx9Ce": {
        "id": "141Kx9Ce",
        "title": "Flocking control for multi-agent systems with communication optimization",
        "abstract": "In this paper, we consider the flocking control and communication optimization problem for multi-agent systems in a realistic communication environment. In flocking control, it is common to specify the formation by setting the separation distance between neighboring agents and then design the control to maintain the desired formation. However, since communication quality will generally change during flocking in a physical environment, a predefined separation distance might not always be the desired communication distance. In this paper, a distributed scheme integrating potential function and extremum seeking algorithm is proposed to obtain the desired separation distance between neighboring agents in real time. A comprehensive performance index related to the environment is proposed, which captures a trade-off between formation tasks and communication quality. Since it is difficult to calculate the gradient of the performance in physical environments, an adaptive model-free extremum seeking algorithm is designed to solve for the optimal separation distances, which calls for no knowledge of the gradient of performance function. We illustrate the proposed method through simulations.",
        "keywords": [
            "optimisation",
            "optimal separation distances",
            "adaptive model-free extremum seeking algorithm",
            "motion control",
            "flocking control problem",
            "communication optimization problem",
            "mobile robots",
            "multi-robot systems",
            "multi-agent systems",
            "neighboring agents",
            "performance index",
            "gradient methods",
            "potential function integration",
            "multiagent systems",
            "communication quality",
            "bit error rate",
            "real time systems",
            "force",
            "multi agent systems",
            "signal to noise ratio",
            "optimization"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": "Central South University China(Central South University ^),Changsha,China"
            },
            {
                "name": "Jun Peng",
                "org": "Central South University China(Central South University ^),Changsha,China"
            },
            {
                "name": "Weirong Liu",
                "org": "Central South University China(Central South University ^),Changsha,China"
            },
            {
                "name": "Jing Wang",
                "org": "Bethune-Cookman University(Bethune-Cookman University),Daytona Beach,United States"
            },
            {
                "name": "Jiangang Liu",
                "org": "Central South University China(Central South University ^),Changsha,China"
            },
            {
                "name": "Zhiwu Huang",
                "org": "Central South University China(Central South University ^),Changsha,China"
            }
        ],
        "venue": "ACC",
        "year": 2013
    },
    "6xyCOksK": {
        "id": "6xyCOksK",
        "title": "Synchronized Cell-Balancing Charging of Supercapacitors: A Consensus-Based Approach.",
        "abstract": "The switched resistor circuit has been a popular cell balancing scheme in low-power supercapacitor applications. However, the cell balancing performance of the circuit is vulnerable to current variations and resistance deviations with the existing asynchronous cell-balancing (ACB) method. To address this challenge, in this paper, we propose a synchronized cell-balancing (SCB) method based on the consensus theory, with the aim of synchronizing cell voltages during the charging process. First, the cyber-physical modeling of the cell balancing system is presented, where the physical layer models the circuit components and the cyber layer represents the communication topology among cells. Second, a distributed voltage tracker is proposed using a consensus tracking protocol, which benefits from a good scalability. A compensator is designed to stabilize the closed-loop multiple-in\u2013multiple-out (MIMO) system and frequency-domain methods are applied to determine the compensator parameters. A laboratory testbed has been built to verify the effectiveness of the proposed method. Experiment results show that the SCB method has a better tolerance of current variations and resistance deviations than the ACB method.",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Jun Peng",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China"
            },
            {
                "name": "Jianping He",
                "org": "Department of Computer Science, University of Victoria, Victoria, BC, Canada"
            },
            {
                "name": "Zhiwu Huang",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China"
            },
            {
                "name": "Jianping Pan",
                "org": "Department of Computer Science, University of Victoria, Victoria, BC, Canada"
            },
            {
                "name": "Jing Wang",
                "org": ""
            }
        ],
        "venue": "IEEE Trans. Industrial Electronics",
        "year": 2018
    },
    "xcoQDqXq": {
        "id": "xcoQDqXq",
        "title": "A Generalized Extended State Observer for Supercapacitor State of Energy Estimation With Online Identified Model.",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Yanhui Zhou",
                "org": ""
            },
            {
                "name": "Zhiwu Huang",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Jun Peng",
                "org": ""
            },
            {
                "name": "Weirong Liu",
                "org": ""
            },
            {
                "name": "Hongtao Liao",
                "org": ""
            }
        ],
        "venue": "IEEE Access",
        "year": 2018
    },
    "Z7opjNjG": {
        "id": "Z7opjNjG",
        "title": "A Cooperative Charging Protocol for Onboard Supercapacitors of Catenary-Free Trams.",
        "abstract": "Catenary-free trams with an onboard supercapacitor have been an emerging and energy-efficient way for urban rail transportation. However, the high-power charging load from catenary-free trams brings a new challenge to the design of charging systems. The traditional single-module charging system typically suffers from a high power and thermal pressure, which reduces the reliability of the charging system. In this paper, we propose a multimodule charging system to improve the system reliability by decomposing power pressure to multiple charging modules. Specifically, a cooperative charging protocol is proposed to improve the dynamic performance of the charging system by suppressing the current imbalance and avoiding the current overshoot during the startup process. First, we mathematically model the multimodule charging system using the state-space averaging method and graph theory. Second, the cooperative charging protocol is designed using the leader\u2013follower consensus algorithm, where the virtual leader represents the desired charging current for each module with a warm-start mechanism. Third, multiple-input multiple-output root locus technique is exploited to characterize the dynamic performance of the charging system. Both simulation and experiment results show that the proposed protocol effectively suppresses the imbalance and avoids the overshoot during the startup of the charging system.",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Jun Peng",
                "org": ""
            },
            {
                "name": "Jianping He",
                "org": "Department of Computer Science, University of Victoria, Victoria, BC, Canada"
            },
            {
                "name": "Rong Zhou",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China"
            },
            {
                "name": "Zhiwu Huang",
                "org": ""
            },
            {
                "name": "Jianping Pan",
                "org": "Department of Computer Science, University of Victoria, Victoria, BC, Canada"
            }
        ],
        "venue": "IEEE Trans. Contr. Sys. Techn.",
        "year": 2018
    },
    "6vE4e8JH": {
        "id": "6vE4e8JH",
        "title": "A Generalized Extended State Observer for Supercapacitor State of Energy Estimation With Online Identified Model.",
        "abstract": "The state of energy (SoE) is a critical indicator for energy management in supercapacitor (SC) energy storage systems. The estimation accuracy of the SoE relies on the model fidelity, which means that the model parameters are required to be identified online to mitigate the aging effect. However, since the SC model is naturally nonlinear and high dimensional, it is typically difficult to identify the model parameters online. To address this issue, in this paper, we propose a generalized extended state observer (GESO) for SC SoE estimation based on an online identified model. A nonlinear mathematical model for SC is established based on the three branch equivalent circuit models, where the model parameters are online estimated with a designed modified recursive least square. A GESO is designed to estimate the SoE of SC in real time. A laboratory test bed has been built to verify the effectiveness of the proposed method. The experiment results show that the proposed method provides a better SoE estimation accuracy than the existing methods.",
        "keywords": "",
        "authors": [
            {
                "name": "Yanhui Zhou",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China"
            },
            {
                "name": "Zhiwu Huang",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China"
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Jun Peng",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China"
            },
            {
                "name": "Weirong Liu",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China"
            },
            {
                "name": "Hongtao Liao",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China"
            }
        ],
        "venue": "IEEE Access",
        "year": 2018
    },
    "bYyJ5zNV": {
        "id": "bYyJ5zNV",
        "title": "Energy Sharing of Zero-Energy Buildings: A Consensus-Based Approach.",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Hongtao Liao",
                "org": ""
            },
            {
                "name": "Jun Peng",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Chengzhang Lyu",
                "org": ""
            },
            {
                "name": "Zhiwu Huang",
                "org": ""
            }
        ],
        "venue": "IEEE Access",
        "year": 2019
    },
    "9oAAjSIz": {
        "id": "9oAAjSIz",
        "title": "Cooperative control and communication optimization for networked multi-agent systems with nonholonomic constraints",
        "abstract": "This paper presents a cooperative formation control on networked multi-agent systems, in which the mobile agents have nonholonomic constraints. To simplify the control design, the dynamics of agents are first transformed into chained form. Based on it, a formation cooperative control scheme is derived from the conventional consensus control law which has been applied to address the nonholonomic constraints. A desired distance among agents is introduced into the consensus control law to let the agent maintain certain range among them and keep formation. The distance is determined by communication quality which is described by Shannon capacity outage probability. Then a model-free extremum seeking algorithm is used to find the best distance among agents. The proposed formation scheme combing extremum seeking can optimize the communication quality of the formation for network agents with nonholonomic constraints. The simulation is provided to validate its feasibility and effectiveness.",
        "keywords": [
            "agent dynamics",
            "robot dynamics",
            "control design",
            "agent distance",
            "control system synthesis",
            "cooperative formation control",
            "mobile robots",
            "multi-robot systems",
            "consensus control law",
            "multi-agent systems",
            "networked multiagent system",
            "model-free extremum seeking algorithm",
            "mobile agent",
            "communication optimization",
            "position control",
            "shannon capacity outage probability",
            "communication quality",
            "nonholonomic constraint",
            "probability"
        ],
        "authors": [
            {
                "name": "Weirong Liu",
                "org": ""
            },
            {
                "name": "Feng Zhou",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Jianming Xiao",
                "org": ""
            },
            {
                "name": "Jing Wang",
                "org": ""
            },
            {
                "name": "Mengfei Wen",
                "org": ""
            },
            {
                "name": "Jun Peng",
                "org": ""
            }
        ],
        "venue": "ROBIO",
        "year": 2012
    },
    "layfme34": {
        "id": "layfme34",
        "title": "Fair Resource Allocation for System Throughput Maximization in Mobile Edge Computing.",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Zhengfa Zhu",
                "org": ""
            },
            {
                "name": "Jun Peng",
                "org": ""
            },
            {
                "name": "Xin Gu",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Kaiyang Liu",
                "org": ""
            },
            {
                "name": "Zhuofu Zhou",
                "org": ""
            },
            {
                "name": "Weirong Liu",
                "org": ""
            }
        ],
        "venue": "IEEE Access",
        "year": 2018
    },
    "lOwbpqsX": {
        "id": "lOwbpqsX",
        "title": "Fair Resource Allocation for System Throughput Maximization in Mobile Edge Computing.",
        "abstract": "Communication resource allocation is important for improving the performance of users in mobile edge computing (MEC) scenarios. In existing studies, the users in the MEC system typically suffer from unfair resource allocation, which results in the inefficient resource utilization and degraded user performance. To address this challenge, in this paper we propose a fair resource allocation approach to maximize the overall network throughput, under the constraint of each mobile user\u2019s minimum transmission rate. We formulate the problem as a fair Nash bargaining resource allocation game, and the existence and uniqueness of the solution to this game model are analyzed. By adopting the time-sharing variable, we obtain the near optimal bargaining resource allocation strategy for the mixed integer nonlinear programming optimization. The user\u2019s priority is further considered in the iterative implementation of the proposed algorithm by considering the time delay constraint of users. Simulation results show that the proposed scheme outperforms existing methods in terms of resource allocation fairness and overall system throughput.",
        "keywords": "",
        "authors": [
            {
                "name": "Zhengfa Zhu",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China"
            },
            {
                "name": "Jun Peng",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China"
            },
            {
                "name": "Xin Gu",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China"
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Kaiyang Liu",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China"
            },
            {
                "name": "Zhuofu Zhou",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China"
            },
            {
                "name": "Weirong Liu",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China"
            }
        ],
        "venue": "IEEE Access",
        "year": 2018
    },
    "u1d5n5f8": {
        "id": "u1d5n5f8",
        "title": "A Highly Efficient and Reliable Power Scheme Using Improved Push-Pull Forward Converter for Heavy-Duty Train Applications.",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Liran Li",
                "org": ""
            },
            {
                "name": "Zhiwu Huang",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Xiaohui Qu",
                "org": ""
            },
            {
                "name": "Jun Peng",
                "org": ""
            }
        ],
        "venue": "JACIII",
        "year": 2016
    },
    "YX8cEXUt": {
        "id": "YX8cEXUt",
        "title": "An adaptive parallel charging system for energy-storage urban rails",
        "abstract": "In this paper, an adaptive parallel charging system is designed for energy-storage urban rail vehicles. The main circuit of the charging system is chosen with two parallel buck converters. The state space model of the charging system is derived with averaging method. Then an adaptive model-free extremum seeking charging controller is designed. Different from existing model-based charging methods, the proposed strategy calls for no knowledge of urban rail vehicles and hence has a wider range of applications. We further show that the proposed charging method can suppress the current imbalance between two parallel buck converters efficiently. The effectiveness of the proposed charging strategy is proved with rigorous theoretical analysis. Moreover, experiment results from a prototype parallel charging system verify the theoretical analysis.",
        "keywords": [],
        "authors": [
            {
                "name": "Heng Li",
                "org": "central south university"
            },
            {
                "name": "Jun Peng",
                "org": "central south university"
            },
            {
                "name": "Jing Wang",
                "org": "bradley university"
            },
            {
                "name": "Weirong Liu",
                "org": "central south university"
            },
            {
                "name": "Zhiwu Huang",
                "org": "central south university"
            }
        ],
        "venue": "ACC",
        "year": 2015
    },
    "UExDT1lf": {
        "id": "UExDT1lf",
        "title": "An Improved TL Buck Converter for Fast-Charging Energy Storage System Using UCs.",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Bin Chen",
                "org": ""
            },
            {
                "name": "Zhiwu Huang",
                "org": ""
            },
            {
                "name": "Rui Zhang",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Zhihui Wu",
                "org": ""
            }
        ],
        "venue": "JACIII",
        "year": 2016
    },
    "wtiZkPVr": {
        "id": "wtiZkPVr",
        "title": "An MPC Control System for Onboard Ultracapacitors with Maximum Current Constraint.",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Rong Zhou",
                "org": ""
            },
            {
                "name": "Zhiwu Huang",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Jun Peng",
                "org": ""
            },
            {
                "name": "Yu Song",
                "org": ""
            }
        ],
        "venue": "JACIII",
        "year": 2017
    },
    "lTok6qTj": {
        "id": "lTok6qTj",
        "title": "Flocking of Mobile Agents Using a New Interaction Model: A Cyber-Physical Perspective.",
        "abstract": "The attraction repulsion (AR) model has been a common mathematical framework to emulate the interactions among mobile agents and to design rigid flocking laws. A main drawback of the AR model is that environment effects are not taken into account in the model. This means that rigid flocking laws can not react to the change of environments. In this paper, we make an attempt to design flocking systems that are adaptive to the change of communication environments. The flocking system is modeled as a cyber-physical system, where the cyber layer and control layer are designed systematically. In the cyber layer, a new interaction model is proposed by considering communication parameters of the environment. In the control layer, distributed controllers are designed for mobile agents with switching topology using the proposed interaction model. It is shown that the proposed flocking law can react to change of communication environments and guarantee the optimal communication link between agents. The stability and convergence of the flocking system are analyzed with nonsmooth techniques. Numerical simulations are provided to illustrate the effectiveness of the design.",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Jun Peng",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China"
            },
            {
                "name": "Xiaoyong Zhang",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China"
            },
            {
                "name": "Zhiwu Huang",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China"
            }
        ],
        "venue": "IEEE Access",
        "year": 2017
    },
    "L8vANvh2": {
        "id": "L8vANvh2",
        "title": "A generalized extended state observer for supercapacitor state of charge estimation under disturbances.",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Yanhui Zhou",
                "org": ""
            },
            {
                "name": "Zhiwu Huang",
                "org": ""
            },
            {
                "name": "Jun Peng",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Hongtao Liao",
                "org": ""
            }
        ],
        "venue": "ACC",
        "year": 2017
    },
    "NM0OxXoM": {
        "id": "NM0OxXoM",
        "title": "Robust and accurate state-of-charge estimation for lithium-ion batteries using generalized extended state observer.",
        "abstract": "With the wide application of Lithium-ion (Li-ion) batteries in electric vehicles and unmanned aerial vehicles (UAVs), it is becoming more important and urgent to estimate the battery state to extend the operation range of electric vehicles or UAVs. Existing state of charge (SOC) estimation methods are highly model-based, which are difficult to be implemented in different scenarios. In this paper, we propose a generalized extended state observer (GESO) based SOC estimation method, where the accurate model is unnecessary, which can be effectively tracked by the observer. Thus, a first order RC model is utilized in GESO to capture the characteristics of Li-ion batteries. By appropriately designing a disturbance compensation gain, the GESO is applied for the nonintegral-chain system that is subject to uncertainties and nonlinear parameters of Li-ion batteries. Experiment results show that the proposed method has a good performance and robustness on SOC estimation of the battery. The SOC estimation results are found to be consistent with the reference SOC with less chattering than sliding mode observer, where the error is within 2% under both the known and unknown initial SOC value cases.",
        "keywords": "",
        "authors": [
            {
                "name": "Yu Song",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China 410075"
            },
            {
                "name": "Weirong Liu",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China 410075"
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Yanhui Zhou",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China 410075"
            },
            {
                "name": "Zhiwu Huang",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China 410075"
            },
            {
                "name": "Fu Jiang",
                "org": ""
            }
        ],
        "venue": "SMC",
        "year": 2017
    },
    "Q62Py6ew": {
        "id": "Q62Py6ew",
        "title": "Consensus control for state-of-energy balancing between the supercapacitor modules in cyber-physical energy system.",
        "abstract": "Recent advancement in the field of electrical technology and cyber-physical energy system (CPES) has brought the key towards challenging issues regarding transparency of information management and efficient allocation of energy. This paper is dedicated to a CPES that deals with an electric light rail that involves large number of distributed and globally interconnected supercapacitor energy storage modules, with the aim of efficient fusion of information, control protocol and energy. The autonomous modules estimate local state of energy and share the information via the communication network. A consensus control strategy is proposed to reach the balanced state of energy between these distributed supercapacitor modules with the advantages in terms of increasing efficiency and reducing time consumption of energy transfer. The proposed method enforces the CPES constraints specific to the particular supercapacitor modules in the electric light rails. Experimental results are provided to verify the effectiveness of the proposed state of energy balancing method.",
        "keywords": "",
        "authors": [
            {
                "name": "Chengzhang Lyu",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China 410083, Hunan Engineering Laboratory of Rail Vehicles Braking Technology, Changsha, China 410083"
            },
            {
                "name": "Zhiwu Huang",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China 410083, Hunan Engineering Laboratory of Rail Vehicles Braking Technology, Changsha, China 410083"
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Yanhui Zhou",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China 410083, Hunan Engineering Laboratory of Rail Vehicles Braking Technology, Changsha, China 410083"
            },
            {
                "name": "Jun Peng",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China 410083, Hunan Engineering Laboratory of Rail Vehicles Braking Technology, Changsha, China 410083"
            },
            {
                "name": "Yingze Yang",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China 410083, Hunan Engineering Laboratory of Rail Vehicles Braking Technology, Changsha, China 410083"
            }
        ],
        "venue": "SMC",
        "year": 2017
    },
    "Ot4icAF0": {
        "id": "Ot4icAF0",
        "title": "A rapid cell voltage balancing scheme for supercapacitor based energy storage systems for urban rail vehicles",
        "abstract": "Supercapacitors are widely used in energy storage systems (ESS) due to the merits including high power density, relatively long life cycle, and fast charging/discharging capability. Recently, it is becoming possible to use supercapacitor based ESS as the single energy source to power an urban rail vehicle. Cell voltage balancing control is necessary for the ESSs where supercapacitor cells are connected in series in order to have safe and reliable operations. A typical charging cycle of onboard supercapacitor stack is around 30 s. A high voltage balancing current is demanded in order to realize cell voltage balancing within the charging courses. In this paper, a new voltage balancing circuit, which is derived from an improved push\u2013pull converter and with high current capability, is proposed for supercapacitor based ESS applications. A voltage balancing algorithm based on predicted cell behaviors is proposed to shorten the cell balancing time and improve the cell balancing efficiency. Simulation and experimental results are provided to verify the effectiveness and advantages of the proposed cell voltage balancing system.",
        "keywords": [
            "Supercapacitor",
            "Energy storage system",
            "Urban rail vehicle",
            "Cell voltage balancing circuit",
            "Cell voltage balancing control"
        ],
        "authors": [
            {
                "name": "Liran Li",
                "org": "School of Information Science and Engineering, Central South University, Changsha 410075, China;"
            },
            {
                "name": "Zhiwu Huang",
                "org": "School of Information Science and Engineering, Central South University, Changsha 410075, China;"
            },
            {
                "name": "Heng Li",
                "org": "School of Information Science and Engineering, Central South University, Changsha 410075, China;"
            },
            {
                "name": "Jun Peng",
                "org": "School of Information Science and Engineering, Central South University, Changsha 410075, China;"
            }
        ],
        "venue": "Electric Power Systems Research",
        "year": 2017
    },
    "z9lRu6Xs": {
        "id": "z9lRu6Xs",
        "title": "A High-Efficiency Voltage Equalization Scheme for Supercapacitor Energy Storage System in Renewable Generation Applications",
        "abstract": "Due to its fast charge and discharge rate, a supercapacitor-based energy storage system is especially suitable for power smoothing in renewable energy generation applications. Voltage equalization is essential for series-connected supercapacitors in an energy storage system, because it supports the system\u2019s sustainability and maximizes the available cell energy. In this paper, we present a high-efficiency voltage equalization scheme for supercapacitor energy storage systems in renewable generation applications. We propose an improved isolated converter topology that uses a multi-winding transformer. An improved push-pull forward circuit is applied on the primary side of the transformer. A coupling inductor is added on the primary side to allow the switches to operate under the zero-voltage switching (ZVS) condition, which reduces switching losses. The diodes in the rectifier are replaced with metal-oxide-semiconductor field-effect transistors (MOSFETs) to reduce the power dissipation of the secondary side. In order to simplify the control, we designed a controllable rectifying circuit to achieve synchronous rectifying on the secondary side of the transformer. The experimental results verified the effectiveness of the proposed design.",
        "keywords": "",
        "authors": [
            {
                "name": "Liran Li",
                "org": ""
            },
            {
                "name": "Zhiwu Huang",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Honghai Lu",
                "org": ""
            }
        ],
        "venue": "Sustainability",
        "year": 2016
    },
    "SVHOuhn4": {
        "id": "SVHOuhn4",
        "title": "A cooperative charging strategy for onboard supercapacitors of catenary-free trams",
        "abstract": "In this paper, a cooperative charging strategy is proposed for onboard supercapacitors of catenary-free trams. The multi-module charging system consists of n buck converters connected in parallel. The parallel-input parallel-output (PIPO) charging system is modeled mathematically using the averaging method. A cooperative constant-current charging control strategy is designed using the leader-follower consensus approach, where the virtual leader represents the desired charging current for each charging module with a warm-start mechanism. The cooperative charging approach provides dual benefits of both excellent dynamic performance and good reliability. Simulation and experiment results are provided to illustrate the effectiveness of the design.",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Jun Peng",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China, 410075"
            },
            {
                "name": "Rong Zhou",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China, 410075"
            },
            {
                "name": "Zhiwu Huang",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China, 410075"
            },
            {
                "name": "Jianping Pan",
                "org": "Department of Computer Science, University of Victoria, Victoria, B.C., Canada, V8W3P6"
            }
        ],
        "venue": "european conference on cognitive ergonomics",
        "year": 2016
    },
    "9hr0WZ4u": {
        "id": "9hr0WZ4u",
        "title": "An adaptive charging control strategy for ultracapacitor light rail vehicles",
        "abstract": "In this paper, an adaptive extremum seeking control strategy with sliding mode is develop to charge the ultracapacitor light rail vehicles. Compared with existing model-based charging algorithms, the proposed extremum seeking (ES) charging control strategy is model-free, which implies that it can handle the ageing effect of ultracapacitors well. Moreover, a sliding mode mechanism is embedded into the charging controller to suppress the disturbances introduced by sensors. Simulation and experiment results are presented to show the effectiveness of the proposed design.",
        "keywords": "",
        "authors": [
            {
                "name": "Rong Zhou",
                "org": "School of Information Science and Engineering, Central South University, Changsha 410075, China"
            },
            {
                "name": "Zhiwu Huang",
                "org": "School of Information Science and Engineering, Central South University, Changsha 410075, China"
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Zhihui Wu",
                "org": "School of Information Science and Engineering, Central South University, Changsha 410075, China"
            },
            {
                "name": "Jun Peng",
                "org": "School of Information Science and Engineering, Central South University, Changsha 410075, China"
            }
        ],
        "venue": "european conference on cognitive ergonomics",
        "year": 2016
    },
    "8VpRWXZ2": {
        "id": "8VpRWXZ2",
        "title": "A distributed ESO based cooperative current-sharing strategy for parallel charging systems under disturbances",
        "abstract": "In this paper, a distributed extended state observer (ESO) based cooperative control is proposed to achieve current-sharing for parallel chargers under disturbances in energy storage type light rail vehicle systems. By treating the parallel charging system as a nonlinear and non-identical multiagent system, the current-sharing objective is converted as a distributed leader-follower consensus problem. A distributed ESO is designed to observe total disturbances with the known information from the established mathematical model of subchargers. A tracking differentiator (TD) is established to provide a transitional process for the reference signal to increase the dynamical performance and robustness. Based on ESO and TD, a distributed cooperative control protocol is proposed. Simulation and experimental results are provided to verify the disturbance rejection ability, feasibility and practicability of the proposed distributed current-sharing control method.",
        "keywords": "",
        "authors": [
            {
                "name": "Yanhui Zhou",
                "org": "School of Information Science and Engineering, Central South University, Changsha 410075, China"
            },
            {
                "name": "Zhiwu Huang",
                "org": "School of Information Science and Engineering, Central South University, Changsha 410075, China"
            },
            {
                "name": "Weirong Liu",
                "org": "School of Information Science and Engineering, Central South University, Changsha 410075, China"
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Hongtao Liao",
                "org": "School of Information Science and Engineering, Central South University, Changsha 410075, China"
            }
        ],
        "venue": "european conference on cognitive ergonomics",
        "year": 2016
    },
    "9APa3a52": {
        "id": "9APa3a52",
        "title": "Sliding model control based on estimation of optimal slip ratio for railway wheel slide protection using extremum seeking",
        "abstract": "It is very important for railway vehicles to have a good braking performance to avoid the phenomenon of idling and skidding, which can be implemented by looking for and keeping an optimal slip ratio. The optimal slip ratio is a value existing in the creep zone of functions between friction coefficient and slip ratio corresponding to the maximum adhesion. Controller based on the sliding mode control needs to be entered an reference slip ratio which can be used to find out the optimal control by the designer and can be tracked by actual slip ratio by the controller. Moreover, as an indispensable factor for calculating slip ratio, vehicle velocity is estimated by the proposed algorithm based on locomotive dynamic model. Then the optimal control ensures the actual slip ratio is equal to or close to the best reference slip ratio generated by extremum seeking algorithm dynamically. According to those functions, the optimal slip ratio changes dynamically once the pavement behavior changes. The simulation result demonstrates that compared with constant reference slip ratios, the proposed dynamical seeking algorithm for optimal reference slip ratio achieves the effect of real-time adjustment for braking torque, which prevents the brake torque from being too large or small and guarantees the braking performance.",
        "keywords": "",
        "authors": [
            {
                "name": "Qing Peng",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China"
            },
            {
                "name": "Jianfeng Liu",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China"
            },
            {
                "name": "Zhiwu Huang",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China"
            },
            {
                "name": "Weirong Liu",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China"
            },
            {
                "name": "Heng Li",
                "org": ""
            }
        ],
        "venue": "european conference on cognitive ergonomics",
        "year": 2016
    },
    "6VuPrJBi": {
        "id": "6VuPrJBi",
        "title": "A Fast servoing strategy for nonholonomic mobile robot with RGB-D sensing",
        "abstract": "In this paper, a servoing controller composing both homographic relation and direct depth information is designed without decoupling the depth as past contributions have done. The servoing strategy does not need homograghy matrix decomposing to get rotation and displacement, or massive depth data computing, leading to less complex in calculation and faster in operation. The wheeled mobile robot computes the vector normal of and the distance to the feature plane to obtain relative current pose with a fixed RGB-D sensor mounted in direction of the robot linear velocity. Simulation and experiment results are shown for feasibility verification of the RGB-D servoing strategy.",
        "keywords": "",
        "authors": [
            {
                "name": "Yezhang Tu",
                "org": "School of Information Science and Engineering, Central South University, Changsha, 410075"
            },
            {
                "name": "Zhiwu Huang",
                "org": "School of Information Science and Engineering, Central South University, Changsha, 410075"
            },
            {
                "name": "Wentao Yu",
                "org": "College of Computer and Information Engineering, Central South University of Forestry and Technology, Changsha 410004"
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Fu Jiang",
                "org": "School of Information Science and Engineering, Central South University, Changsha, 410075"
            }
        ],
        "venue": "chinese control and decision conference",
        "year": 2017
    },
    "VEDwthsg": {
        "id": "VEDwthsg",
        "title": "A novel estimator for adhesion force of railway vehicles braking systems and reference speed calculation",
        "abstract": "In this paper, sliding mode control is designed as the controller for railway vehicle braking systems and a novel estimator is introduced to estimate the immeasurable adhesion force torque, which is based on the locomotive wheel model and a proportional integral control. Then value of adhesion force can be achieved by a simple division transformation of the estimated adhesion force torque. The value of adhesion force calculated from the estimation of adhesion force torque has three benefits. Due to the accuracy of estimated adhesion force, it can be used to calculate the reference speed and used as a necessary parameter of controller. Whatu0027s more, it can be used as an input of the algorithm for calculating the optimal slip rate, which lays the foundation for future research. The simulation verifies the performance of the proposed estimator.",
        "keywords": "",
        "authors": [
            {
                "name": "Jianfeng Liu",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China, 410075"
            },
            {
                "name": "Qing Peng",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China, 410075"
            },
            {
                "name": "Zhiwu Huang",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China, 410075"
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Dongyang Wang",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China, 410075"
            },
            {
                "name": "Yuanjun Chen",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China, 410075"
            },
            {
                "name": "Fu LinZhou",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China, 410075"
            }
        ],
        "venue": "chinese control and decision conference",
        "year": 2017
    },
    "NMtYCXCI": {
        "id": "NMtYCXCI",
        "title": "Synchronized Cell-Balancing Charging of Supercapacitors",
        "abstract": "Abstract   As a classical cell balancing solution in low-power supercapacitor applications, the switched resistor circuit is vulnerable to resistance deviation effects with existing cell balancing methods. In this paper, we propose a synchronized cell balancing method for switched resistor circuits based on the consensus theory and a cyber-physical approach, with the aim of synchronizing cell voltages before they are fully charged. It is shown that the proposed cell-balancing algorithm is robust to resistance deviation effects. Extensive simulations are provided to show the effectiveness of the proposed method.",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China 410087"
            },
            {
                "name": "Heng Li",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China 410087"
            },
            {
                "name": "Jun Peng",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China 410087"
            },
            {
                "name": "Jianping He",
                "org": "Dept. of Automation, Shanghai Jiao Tong University, and Key Laboratory of System Control and Information Processing, Shanghai, China 200240"
            },
            {
                "name": "Zhiwu Huang",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China 410087"
            },
            {
                "name": "Jianping Pan",
                "org": "Dept. of Automation, Shanghai Jiao Tong University, and Key Laboratory of System Control and Information Processing, Shanghai, China 200240"
            }
        ],
        "venue": "IFAC-PapersOnLine",
        "year": 2017
    },
    "fiS0pBc9": {
        "id": "fiS0pBc9",
        "title": "An improved voltage balance strategy for renewable generation energy storage system",
        "abstract": "Active voltage balance has been a popular voltage balance method in high power supercapacitor applications. In this paper, an improved active voltage balance strategy is proposed for renewable generation energy storage systems. First, we propose an improved active voltage balance circuit based on the multi-winding transformer. A clamping capacitor is inserted in the primary side of the transformer to provide a better transient performance. Then a simple but efficient control logic is proposed to decide the sequence of cells to be charged. The supercapacitor is modeled as a RC equivalent circuit. Instead of balancing the terminal voltage of cells, we use an constant-current charging method to identify the parameters of supercapacitors, and calculate the equivalent capacitor voltage, which is further used in the voltage balance. Experiment results are provided to illustrate the effectiveness of the design.",
        "keywords": "",
        "authors": [
            {
                "name": "Muxin Han",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China, 410075"
            },
            {
                "name": "Fu Jiang",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Rong Zhou",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China, 410075"
            },
            {
                "name": "Zhiwu Huang",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China, 410075"
            },
            {
                "name": "Jun Peng",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China, 410075"
            }
        ],
        "venue": "european conference on cognitive ergonomics",
        "year": 2017
    },
    "Lmmezk9X": {
        "id": "Lmmezk9X",
        "title": "Accurate voltage equalization of supercapacitors with online identification model",
        "abstract": "Voltage equalization scheme is used to solve the voltage imbalance problem between serial connected supercapacitors. The inner capacitor voltage instead of terminal voltage based balancing scheme has been proven to be more accurate. The inner capacitor voltage are traditionally deduced through offline identified model parameters, which are variable due to the effect of terminal voltage, interference, and temperature, which will cause undesirable balancing deviation. To address the problem, we propose an online identified model based voltage equalization scheme to improve the equalization accuracy. The scheme is achieved by identifying model parameters through recursive-least square (RLS) technique, which has the advantage of simplicity, easy practicability. Experimental results are given to verify the effectiveness and high accuracy of the proposed cell balancing method.",
        "keywords": "",
        "authors": [
            {
                "name": "Xiaoyong Zhang",
                "org": "School of Information Science and Engineering, Central South University, Hunan Engineering Laboratory of Rail Vehicles Braking Technology, ChangSha, China 410075"
            },
            {
                "name": "Yun Jiao",
                "org": "School of Information Science and Engineering, Central South University, Hunan Engineering Laboratory of Rail Vehicles Braking Technology, ChangSha, China 410075"
            },
            {
                "name": "Hongtao Liao",
                "org": "School of Information Science and Engineering, Central South University, Hunan Engineering Laboratory of Rail Vehicles Braking Technology, ChangSha, China 410075"
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Yanhui Zhou",
                "org": "School of Information Science and Engineering, Central South University, Hunan Engineering Laboratory of Rail Vehicles Braking Technology, ChangSha, China 410075"
            },
            {
                "name": "Zhiwu Huang",
                "org": "School of Information Science and Engineering, Central South University, Hunan Engineering Laboratory of Rail Vehicles Braking Technology, ChangSha, China 410075"
            }
        ],
        "venue": "applied power electronics conference",
        "year": 2018
    },
    "apwOBQ16": {
        "id": "apwOBQ16",
        "title": "An efficient voltage equalization algorithm for low-power supercapacitor applications",
        "abstract": "Voltage equalization of series-connected supercapacitors (SCs) is of practical significance for the life and security of supercapacitors. In this paper, we proposed an efficient voltage equalization algorithm based on the consensus theory applying for switched shunting resistor circuit of supercapacitor (SC). In the proposed equilibrium strategy, a proportional-integral (PI) observer is designed to estimate the internal capacitance voltage of SCs. Then, by comparing the observation value of internal capacitance voltage with those of its neighbors, the voltages of SCs are balanced before they are fully charged and even after charging is completed. The experiment results show that the proposed method has significant superiority and wider applicability than other exiting methods for equalizing voltage.",
        "keywords": "",
        "authors": [
            {
                "name": "Yu Song",
                "org": "School of Information Science and Engineering, Central South University, Hunan Engineering Laboratory of Rail Vehicles Braking Technology, ChangSha, China 410075"
            },
            {
                "name": "Weirong Liu",
                "org": "School of Information Science and Engineering, Central South University, Hunan Engineering Laboratory of Rail Vehicles Braking Technology, ChangSha, China 410075"
            },
            {
                "name": "Hongtao Liao",
                "org": "School of Information Science and Engineering, Central South University, Hunan Engineering Laboratory of Rail Vehicles Braking Technology, ChangSha, China 410075"
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Yun Jiao",
                "org": "School of Information Science and Engineering, Central South University, Hunan Engineering Laboratory of Rail Vehicles Braking Technology, ChangSha, China 410075"
            },
            {
                "name": "Jun Peng",
                "org": "School of Information Science and Engineering, Central South University, Hunan Engineering Laboratory of Rail Vehicles Braking Technology, ChangSha, China 410075"
            },
            {
                "name": "Zhiwu Huang",
                "org": "School of Information Science and Engineering, Central South University, Hunan Engineering Laboratory of Rail Vehicles Braking Technology, ChangSha, China 410075"
            }
        ],
        "venue": "applied power electronics conference",
        "year": 2018
    },
    "BnHdAXsm": {
        "id": "BnHdAXsm",
        "title": "SoH-Aware Charging of Supercapacitors with Energy Efficiency Maximization",
        "abstract": "Recent years have seen significant advances in supercapacitor-based applications in portable electronics, where the switching resistor circuit acts as a common cell balancing circuit when charging the supercapacitors. However, existing charging control methods suffer from low energy efficiency, leading to considerable energy loss, and thermal heating. In this paper, we propose a state-of-health (SoH)-aware energy-efficient charging method to maximize the energy efficiency of supercapacitors during the charging process. First, we provide a sufficient and necessary condition to maximize the energy efficiency. Then, an online SoH estimation algorithm is designed to estimate capacitance and balancing resistance in real time. Thereafter, an SoH-aware energy-efficient charging algorithm is further proposed to be implemented in microcontrollers. A charger prototype has been built to verify the effectiveness of the proposed charging algorithm. Extensive simulation and experiment results show that the energy efficiency of the proposed design is improved considerably when compared with existing methods.",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Jun Peng",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China"
            },
            {
                "name": "Yanhui Zhou",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China"
            },
            {
                "name": "Jianping He",
                "org": "Department of AutomationShanghai Jiao Tong University"
            },
            {
                "name": "Zhiwu Huang",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China"
            },
            {
                "name": "Liang He",
                "org": "Department of Computer Science and Engineering, University of Colorado Denver, Denver, CO, USA"
            },
            {
                "name": "Jianping Pan",
                "org": "Department of Computer Science, University of Victoria, Victoria, BC, Canada"
            }
        ],
        "venue": "IEEE Transactions on Energy Conversion",
        "year": 2018
    },
    "NO3D94B3": {
        "id": "NO3D94B3",
        "title": "Distributed Voltage Equalization Design for Supercapacitors Using State Observer",
        "abstract": "The switched shunting resistor circuit is a classical and practical passive equalization scheme that nevertheless suffers from the voltage imbalance after the charging process. It results from the discrepancy of the shunting resistor and the physical characteristics of supercapacitor (SC) cells. In this paper, the distributed voltage equalization control strategies with the proportional-integral (PI) observer for the switched shunting resistor circuit are analyzed and compared. First, the charging and equalizing system is modeled as the switched system and the system observability is proved. The decentralized control and consensus control are analyzed and their shortages are presented. Then, the leader\u2013follower cooperative control is proposed to improve the charging time while keeping the equalization performance. Meanwhile, the PI observer is designed to estimate the internal capacitance voltage of an SC precisely to avoid the effect of equal series resistance. The control convergence is proved by using the Lyapunov stability and switched system theory. The experimental results show that the proposed method has much superiority and wide applicability than the existing methods for equalizing voltages of SCs.",
        "keywords": "",
        "authors": [
            {
                "name": "Weirong Liu",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China"
            },
            {
                "name": "Yu Song",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China"
            },
            {
                "name": "Hongtao Liao",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China"
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Xiaoyong Zhang",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China"
            },
            {
                "name": "Yun Jiao",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China"
            },
            {
                "name": "Jun Peng",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China"
            },
            {
                "name": "Zhiwu Huang",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China"
            }
        ],
        "venue": "IEEE Transactions on Industry Applications",
        "year": 2018
    },
    "iBgl2DTz": {
        "id": "iBgl2DTz",
        "title": "A generalized extended state observer for supercapacitor state of charge estimation under disturbances.",
        "abstract": "In this paper, a generalized extended state observer (GESO) is proposed to accurately observe supercapacitoru0027s state of charge (SOC) by counteracting the modeling deviation and disturbances. With the consideration of dynamic modeling uncertainty and disturbances, a nonlinear mathematical model is established based on the three branch equivalent circuit model for supercapacitor (SC). A GESO is designed to observe SCu0027s internal capacitance voltage and modeling error with the known information from the established mathematical model. With the estimated modeling error information, a compensation control law is designed to eliminate deviation, which results in an accurate internal capacitance voltage observation. An accurate SOC for SC is obtained with the estimated parameters. Experimental results from a synchronous buck circuit based test platform are provided to verify the feasibility and superiority for SOC observation by GESO.",
        "keywords": "",
        "authors": [
            {
                "name": "Yanhui Zhou",
                "org": "School of Information Science and Engineering, Central South University, Changsha 410075, China"
            },
            {
                "name": "Zhiwu Huang",
                "org": "School of Information Science and Engineering, Central South University, Changsha 410075, China"
            },
            {
                "name": "Jun Peng",
                "org": "School of Information Science and Engineering, Central South University, Changsha 410075, China"
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Hongtao Liao",
                "org": "School of Information Science and Engineering, Central South University, Changsha 410075, China"
            }
        ],
        "venue": "ACC",
        "year": 2017
    },
    "5MV19ZI9": {
        "id": "5MV19ZI9",
        "title": "Enhanced Sliding Mode Control and Online Estimation of Optimal Slip Ratio for Railway Vehicle Braking Systems",
        "abstract": "This paper proposes an optimal anti-locking control scheme so as to improve the braking performance of railway vehicles. The controlling effect of sliding mode control is improved, and the optimal slip ratio is achieved by extreme seeking algorithm. Firstly, a substitute function for the conventional sign function is proposed. Secondly, a closed loop observer for braking systems is used to enhance the estimation value of adhesion force, which can also be used for calculating reference speed. Finally Sliding Mode Controlbased controller needs to be entered a reference slip ratio called optimal slip ratio, which is searched by extreme seeking algorithm from the functional relationship between slip ratio and friction coefficient. Thus, the maximum adhesion is achieved despite wheel/ rail surface changes. The simulation result demonstrates the effect of real-time adjustment for braking torque, which guarantees the braking performance.",
        "keywords": [
            "Railway vehicles",
            " Enhanced sliding mode control",
            " Observer",
            " Extreme seeking algorithm",
            " Optimal slip ratio"
        ],
        "authors": [
            {
                "name": "Jianfeng Liu",
                "org": ""
            },
            {
                "name": "Qing Peng",
                "org": "Central South University"
            },
            {
                "name": "Zhiwu Huang",
                "org": "Central South University"
            },
            {
                "name": "Weirong Liu",
                "org": "Central South University"
            },
            {
                "name": "Heng Li",
                "org": ""
            }
        ],
        "venue": "International Journal of Precision Engineering and Manufacturing",
        "year": 2018
    },
    "N8jNyM4m": {
        "id": "N8jNyM4m",
        "title": "Voltage Equalization Scheme for Onboard Supercapacitor Based on Sliding Mode Observer",
        "abstract": "In recent years, with the growing population of people swarmed into urban city, supercapacitor tram has been a promising candidate for the current urban rail transportation. However, the series-connection of cells will typically lead to the cell imbalance and dispersion because of the different individual cell properties such as capacitance, internal resistance, self-discharge rate, and environmental conditions. In this paper, a voltage equalization scheme based on an advanced isolated converter topology that utilizes a multi-winding transformer is proposed for onboard supercapacitors of catenary-free trams. Voltage equalization is essential for series-connected supercapacitors in the energy storage system because of the system sustainability and maximizes the available storage energy. An equalizer algorithm based on sliding mode observer is designed. The balancing approach provides both excellent performance and good reliability. Analysis and experiment results are provided to illustrate the effectiveness of the design.",
        "keywords": "",
        "authors": [
            {
                "name": "Hongwei Cao",
                "org": "Central South University, School of Informition Science and Engineering, Changsha, 410075, China"
            },
            {
                "name": "JianFeng Liu",
                "org": "Central South University, School of Informition Science and Engineering, Changsha, 410075, China"
            },
            {
                "name": "Yanhui Zhou",
                "org": "Central South University, School of Informition Science and Engineering, Changsha, 410075, China"
            },
            {
                "name": "Chengzhang Lyu",
                "org": "Central South University, School of Informition Science and Engineering, Changsha, 410075, China"
            },
            {
                "name": "Heng Li",
                "org": "Central South University, School of Informition Science and Engineering, Changsha, 410075, China"
            },
            {
                "name": "Zhiwu Huang",
                "org": "Central South University, School of Informition Science and Engineering, Changsha, 410075, China"
            }
        ],
        "venue": "european conference on cognitive ergonomics",
        "year": 2018
    },
    "dP2aIUjO": {
        "id": "dP2aIUjO",
        "title": "A Cooperative Cell Balancing Approach for Reconfigurable Supercapacitor Energy Storage Systems",
        "abstract": "Reconfigurable supercapacitor energy storage systems have been a promising choice for powering portable electronics since it omits the requirement of passive balancing elements such as resistors in the circuit, which improves the energy efficiency and alleviates the thermal heating effect of the circuit. However, the classical decentralized cell balancing method results in high voltage profiles of cells, which degrades the lifetime of cells in the repeated charging-discharging cycles. To address this challenge, we propose a cooperative cell balancing approach for reconfigurable supercapacitor energy storage systems. In the proposed method, cells communicate with their neighbours to synchronize cell voltages during the charging process. By carefully choosing the communication topology, the voltage profiles of cells can be maintained as low as possible, which alleviates the aging effects and prolongs the lifetime of cells. A laboratory hardware testbed has been built to verify the effectiveness of the proposed method. Extensive experiment results show that the proposed method can prolong the lifetime of cells considerably when compared with the decentralized control method.",
        "keywords": "",
        "authors": [
            {
                "name": "Fu Jiang",
                "org": "Central South University, School of Information Science and Engineering, Changsha, 410075, China"
            },
            {
                "name": "Zhiqiang Meng",
                "org": "Central South University, School of Information Science and Engineering, Changsha, 410075, China"
            },
            {
                "name": "Heng Li",
                "org": "Central South University, School of Information Science and Engineering, Changsha, 410075, China"
            },
            {
                "name": "Hongtao Liao",
                "org": "Central South University, School of Information Science and Engineering, Changsha, 410075, China"
            },
            {
                "name": "Yun Jiao",
                "org": "Central South University, School of Information Science and Engineering, Changsha, 410075, China"
            },
            {
                "name": "Muxin Han",
                "org": "Central South University, School of Information Science and Engineering, Changsha, 410075, China"
            },
            {
                "name": "Jun Peng",
                "org": "Central South University, School of Information Science and Engineering, Changsha, 410075, China"
            },
            {
                "name": "Zhiwu Huang",
                "org": "Central South University, School of Information Science and Engineering, Changsha, 410075, China"
            }
        ],
        "venue": "european conference on cognitive ergonomics",
        "year": 2018
    },
    "Jmcve9yI": {
        "id": "Jmcve9yI",
        "title": "A Temperature-Suppression Charging Strategy for Supercapacitors of Portable Applications",
        "abstract": "In recent years, significant progress have been made in supercapacitor-based portable applications, where the switched-resistors circuit functions as a traditional cell balancing circuit. However, the existing charging control methods lack explicit consideration of the relatively high system temperature, leading to the decrease of the system life span and the serious thermal effect. In this paper, a temperature-suppressed charging method has been proposed to keep the system temperature at a low level during charging process. A proof is provided to demonstrate the effectiveness of this approach. Laboratory hardware setup has been completed and experimental results show that the average temperature of the system can be reduced by at least 1.2 \u00b0C compared with existing methods.",
        "keywords": "",
        "authors": [
            {
                "name": "Yongjie Liu",
                "org": "Central South University, Department of School of Informition Science and Engineering, Changsha, 410083, China"
            },
            {
                "name": "Zhiwu Huang",
                "org": "Central South University, Department of School of Informition Science and Engineering, Changsha, 410083, China"
            },
            {
                "name": "Hongtao Liao",
                "org": "Central South University, Department of School of Informition Science and Engineering, Changsha, 410083, China"
            },
            {
                "name": "Yanhui Zhou",
                "org": "Central South University, Department of School of Informition Science and Engineering, Changsha, 410083, China"
            },
            {
                "name": "Yun Jiao",
                "org": "Central South University, Department of School of Informition Science and Engineering, Changsha, 410083, China"
            },
            {
                "name": "Heng Li",
                "org": "Central South University, Department of School of Informition Science and Engineering, Changsha, 410083, China"
            },
            {
                "name": "Chao Hu",
                "org": "Central South University, Department of School of Informition Science and Engineering, Changsha, 410083, China"
            },
            {
                "name": "Jun Peng",
                "org": "Central South University, Department of School of Informition Science and Engineering, Changsha, 410083, China"
            }
        ],
        "venue": "european conference on cognitive ergonomics",
        "year": 2018
    },
    "ux6aUbNy": {
        "id": "ux6aUbNy",
        "title": "A Current Controller based on SPAACE for Parallel Charging Systems of Energy-Storage Urban Rails",
        "abstract": "Response overshoot is an undesired behavior that acceleraes system aging and even causes damage in high-power electronics system. In this paper, we proposed a current control method for improving dynamic performance of charging systems that serve for energy-storage urban rails. A current controller is implemented to reduce the damage of capacitors and switching devices in the charging system. Specially, set point automatic adjustment with correction enabled (SPAACE) is designed to the control method, with the aim of reducing the current overshoot. Therefore our method can optimize responsiveness of the charging system especially at the beginning of the charging. Compared with the traditional current controller, the main characteristic of the proposed current controller is that it can effectively reduce the current overshoot without compromising the speed of the closed-loop current control. A laboratory testbed has been built to verify the effectiveness of the design. Experiment results show that the proposed method can suppress the current overshooting as intended.",
        "keywords": "",
        "authors": [
            {
                "name": "Xiaoyong Zhang",
                "org": "School of Information Science and Engineering, Central South University, Changsha, 410075, China"
            },
            {
                "name": "Hang Zhang",
                "org": "School of Information Science and Engineering, Central South University, Changsha, 410075, China"
            },
            {
                "name": "Heng Li",
                "org": "School of Information Science and Engineering, Central South University, Changsha, 410075, China"
            },
            {
                "name": "Yanhui Zhou",
                "org": "School of Information Science and Engineering, Central South University, Changsha, 410075, China"
            },
            {
                "name": "Yun Jiao",
                "org": "School of Information Science and Engineering, Central South University, Changsha, 410075, China"
            },
            {
                "name": "Hongtao Liao",
                "org": "School of Information Science and Engineering, Central South University, Changsha, 410075, China"
            },
            {
                "name": "Zhiwu Huang",
                "org": "School of Information Science and Engineering, Central South University, Changsha, 410075, China"
            }
        ],
        "venue": "european conference on cognitive ergonomics",
        "year": 2018
    },
    "EhHc6bYR": {
        "id": "EhHc6bYR",
        "title": "An Efficient Reference Modulation Based Control Strategy for Active Hybrid Energy Management of EVs",
        "abstract": "In the hybrid energy storage system of electric vehicles (EVs), supercapacitors (SCs) are configured to supplement high frequency power loads to reduce battery strains. Continuous supply and quick response to power load through bidirectional power control is of great importance to attain power balance and keep the stability of bus voltage. In this paper, we propose a reference modulation based power management strategy to tackle this problem. Specifically, an adaptive SCs reference current regulation is designed to maintain sustainable power supply for SCs. A discrete lead compensator based reference smoothing control technique is integrated in to bottom layer control in order for quick transient response to stochastic power demand. With the designed SCs current regulation and reference smoothing technique, we aim to reduce the fluctuation of bus voltage. US06 driving cycles are applied in simulation and experiment to verify the effectiveness of the proposed approach.",
        "keywords": "",
        "authors": [
            {
                "name": "Yanhui Zhou",
                "org": "Department of School of Information Science and Engineering, Central South University, Changsha, 410083, China"
            },
            {
                "name": "Zhiwu Huang",
                "org": "Department of School of Information Science and Engineering, Central South University, Changsha, 410083, China"
            },
            {
                "name": "Hongtao Liao",
                "org": "Department of School of Information Science and Engineering, Central South University, Changsha, 410083, China"
            },
            {
                "name": "Heng Li",
                "org": "Department of School of Information Science and Engineering, Central South University, Changsha, 410083, China"
            },
            {
                "name": "Yun Jiao",
                "org": "Department of School of Information Science and Engineering, Central South University, Changsha, 410083, China"
            },
            {
                "name": "Jun Peng",
                "org": "Department of School of Information Science and Engineering, Central South University, Changsha, 410083, China"
            }
        ],
        "venue": "european conference on cognitive ergonomics",
        "year": 2018
    },
    "1t6kdCKG": {
        "id": "1t6kdCKG",
        "title": "A Real-Time Layer-Adaptive Wavelet Transform Energy Distribution Strategy in a Hybrid Energy Storage System of EVs",
        "abstract": "In this paper, a real-time energy distribution strategy is designed by a layer-adaptive wavelet transform algorithm and proposed to meet the load power demand while distributing the high-frequency component to supercapacitors and the low-frequency component to batteries in a hybrid energy storage system. In the proposed method, the number of decomposition layers of wavelet transform corresponding to the load power is adaptively determined by dividing the operation zone of supercapacitors into eight cases to respectively distribute the low frequency component to batteries and the remaining high frequency component to supercapacitors. Firstly, since the state of charge of supercapacitors decreases faster as the decomposition layers increases, the state of charge of supercapacitors is divided into eight cases of operation zones. Secondly, since supercapacitors act as the peak power buffer unit, the corresponding number of decomposition layers is finally adaptively determined according to the operation zone of supercapacitors. An experiment testbed is built to verify the effectiveness of the proposed method. Extensive experiment results show that the proposed method provides a better real-time energy sharing between supercapacitors and batteries when compared with the conditional method.",
        "keywords": "",
        "authors": [
            {
                "name": "Jun Peng",
                "org": ""
            },
            {
                "name": "Rui Wang",
                "org": ""
            },
            {
                "name": "Hongtao Liao",
                "org": ""
            },
            {
                "name": "Yanhui Zhou",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Yue Wu",
                "org": ""
            },
            {
                "name": "Zhiwu Huang",
                "org": ""
            }
        ],
        "venue": "Energies",
        "year": 2019
    },
    "xd7SNhOc": {
        "id": "xd7SNhOc",
        "title": "An Adaptive Current Sharing Strategy for Energy Storage Urban Rails Using Extremum Seeking",
        "abstract": "Cooperative proportional-integral (PI) has been a popular current sharing method in many industrial applications for its simplicity and reliability. However, since cooperative PI control is typically implemented in a decentralized way, the parameter tuning of cooperative PI controllers is a time-consuming task when the number of controllers is large. In this paper, we propose an improved cooperative PI controller with adaptive parameter tuning using extremum seeking algorithm. It is shown that parameters of the cooperative PI controllers can be tuned adaptively by extremum seeking algorithm to achieve the precise current sharing among converters. Simulation results are provided to verify the feasibility of the proposed design.",
        "keywords": "",
        "authors": [
            {
                "name": "Hongtao Liao",
                "org": "School of Information Science and Engineering, Central South University, Changsha, 410075, China"
            },
            {
                "name": "Jun Peng",
                "org": "School of Information Science and Engineering, Central South University, Changsha, 410075, China"
            },
            {
                "name": "Heng Li",
                "org": "School of Information Science and Engineering, Central South University, Changsha, 410075, China"
            },
            {
                "name": "Yanhui Zhou",
                "org": "School of Information Science and Engineering, Central South University, Changsha, 410075, China"
            },
            {
                "name": "Zhiwu Huang",
                "org": "School of Information Science and Engineering, Central South University, Changsha, 410075, China"
            }
        ],
        "venue": "world congress on intelligent control and automation",
        "year": 2018
    },
    "2wypETPA": {
        "id": "2wypETPA",
        "title": "An Online Parameter Identification for Ultracapacitor Model by Using Recursive Least Square with Multi-forgetting Factor",
        "abstract": "Reliable parameters information is of great importance for on-board energy management and optimal power control. In this paper, we applies the online strategy of multi-forgetting factor recursive least square algorithm to identify parameters of first-order dynamic model through cyclic operating current. The output voltage of the identified model shows a good agreement with the experimental results, and the results of comparison with curve fitting method highlight the proposed method has great accuracy and convergence.",
        "keywords": "",
        "authors": [
            {
                "name": "Jiayi Bao",
                "org": "School of Information Science and Engineering, Central South University, Changsha>, 410075, China"
            },
            {
                "name": "Jianfeng Liu",
                "org": "School of Information Science and Engineering, Central South University, Changsha>, 410075, China"
            },
            {
                "name": "Zhiwu Huang",
                "org": "School of Information Science and Engineering, Central South University, Changsha>, 410075, China"
            },
            {
                "name": "Weirong Liu",
                "org": "School of Information Science and Engineering, Central South University, Changsha>, 410075, China"
            },
            {
                "name": "Heng Li",
                "org": "School of Information Science and Engineering, Central South University, Changsha>, 410075, China"
            }
        ],
        "venue": "world congress on intelligent control and automation",
        "year": 2018
    },
    "aTLsZYZ3": {
        "id": "aTLsZYZ3",
        "title": "Optimal ultracapacitor permutation and combination for voltage equalization using Rejected Monte Carlo algorithm",
        "abstract": "Abstract\u2013Ultracapacitors are novel energy storage devices with high power density and long cycle life. For practical applications, numerous ultracapacitor monomers need to be connected in series or parallel to form modules, in which the voltage imbalance among monomers induced by technological parameter dispersion would damage ultracapacitors. It is an important issue to achieve the voltage balance with lower energy cost. Instead of designing cell balancing systems to minimize the voltage imbalance, this paper proposes a method for optimized ultracapacitor permutation and combination using Rejected Monte Carlo algorithm. This method not only reduces voltage difference, but also decreases balancing current and energy loss of the equalization circuit. Simulation results are provided to illustrate the effectiveness of the proposed method.",
        "keywords": "",
        "authors": [
            {
                "name": "Jiayi Bao",
                "org": "School of Information Science and Engineering, Central South University, Changsha, 410075, China"
            },
            {
                "name": "Jianfeng Liu",
                "org": "School of Information Science and Engineering, Central South University, Changsha, 410075, China"
            },
            {
                "name": "Zhiwu Huang",
                "org": "School of Information Science and Engineering, Central South University, Changsha, 410075, China"
            },
            {
                "name": "Weirong Liu",
                "org": "School of Information Science and Engineering, Central South University, Changsha, 410075, China"
            },
            {
                "name": "Heng Li",
                "org": "School of Information Science and Engineering, Central South University, Changsha, 410075, China"
            }
        ],
        "venue": "world congress on intelligent control and automation",
        "year": 2018
    },
    "x215VddD": {
        "id": "x215VddD",
        "title": "Railway Optimal Slip Ratio Control Using Extremum Seeking Algorithm With Adaptive Amplitude Tuning",
        "abstract": "The key technology of anti-slip control system is to identify the optimal slip ratio in individual conditions for railway applications. In this paper, an extended state observer (ESO) is proposed for the immeasurable varying adhesion coefficient. With the estimated modeling error information, the deviation is eliminated by the designed compensation control rate, which results in an accurate adhesion coefficient observation. Then an extremum seeking (ES) algorithm with adaptively tuned amplitude is proposed to calculate the optimal slip ratio under current road conditions. Compared with classical ES-based methods, the proposed method has smaller oscillations and better dynamic performance. In order to get the maximum braking force, the feedback linearization control framework is proposed for a nonlinear controller of wheel optimal slip ratio. To increase the stability and robustness of the control system, a Lyapunov function with integral form is constructed. The simulation result demonstrates the effectiveness of the proposed control method.",
        "keywords": "",
        "authors": [
            {
                "name": "Xiaokang Xu",
                "org": "School of Information Science and Engineering, Central South University, Changsha, 410000, China"
            },
            {
                "name": "Jun Peng",
                "org": "School of Information Science and Engineering, Central South University, Changsha, 410000, China"
            },
            {
                "name": "Rui Zhang",
                "org": "School of Information Science and Engineering, Central South University, Changsha, 410000, China"
            },
            {
                "name": "Heng Li",
                "org": "School of Information Science and Engineering, Central South University, Changsha, 410000, China"
            },
            {
                "name": "Shuai Hao",
                "org": "School of Information Science and Engineering, Central South University, Changsha, 410000, China"
            },
            {
                "name": "Zhiwu Huang",
                "org": "School of Information Science and Engineering, Central South University, Changsha, 410000, China"
            }
        ],
        "venue": "world congress on intelligent control and automation",
        "year": 2018
    },
    "MQa5aOKi": {
        "id": "MQa5aOKi",
        "title": "Distributed Control for State-of-Energy Balancing of Supercapacitor Modules in Light Rail Vehicles",
        "abstract": "Supercapacitor energy storage systems (ESS) play a significant role in light rail vehicles LRV with no need for overhead lines and the pantograph. As the ESS of LRV demand short charging time and high-power supply, it is crucial to achieve the rapid energy balancing for series-connected supercapacitor modules of the ESS. To address this issue, this paper proposes a distributed control scheme for state-of-energy (SoE) balancing of supercapacitor modules. In order to provide the sufficient balancing current, the push\u2013pull converter is introduced to transfer the energy among supercapacitor modules in the low working voltage. Then, the distributed SoE balancing strategy is proposed by regulating the balancing circuit according to the SoE deviation of neighboring supercapacitor modules. The ESS prototype is built to validate that the proposed strategy can reduce the balancing time and improve the energy balancing efficiency.",
        "keywords": [
            "Supercapacitors",
            "Decentralized control",
            "Batteries",
            "Integrated circuit modeling",
            "Light rail systems",
            "Centralized control"
        ],
        "authors": [
            {
                "name": "Chengzhang Lyu",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China"
            },
            {
                "name": "Zhiwu Huang",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China"
            },
            {
                "name": "Heng Li",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China"
            },
            {
                "name": "Hongtao Liao",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China"
            },
            {
                "name": "Yingze Yang",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China"
            },
            {
                "name": "Jun Peng",
                "org": "School of Information Science and Engineering, Central South University, Changsha, China"
            },
            {
                "name": "Jing Wang",
                "org": "Department of Electrical and Computer Engineering, Bradley University, Peoria, IL, USA"
            }
        ],
        "venue": "IEEE Transactions on Vehicular Technology",
        "year": 2019
    },
    "arWPnydp": {
        "id": "arWPnydp",
        "title": "Current state and progress of biotransformation technology of steroid compounds",
        "abstract": "Progress of biotransformation technology of steroid compounds was reviewed.The selection of steroid raw materials,selection and improvement of microbial strain and new technologies of biotransformation were discussed,including physical/chemical solubilizing of substrates,new transformation system and improvement of cell permeability.It is forecasted that the proportion of biotransformation technologies increased in the industrial production process of steroid hormone drugs.",
        "keywords": [
            "biotransformation",
            "pharmaceutical intermediates",
            "steroids"
        ],
        "authors": [
            {
                "name": "XU Zhenghong",
                "org": "School of Pharmaceutical Science,Jiangnan University,Wuxi ,China"
            },
            {
                "name": "WU Yan",
                "org": "School of Pharmaceutical Science,Jiangnan University,Wuxi ,China"
            },
            {
                "name": "LI Hui",
                "org": "School of Pharmaceutical Science,Jiangnan University,Wuxi ,China"
            },
            {
                "name": "LI Heng",
                "org": "School of Pharmaceutical Science,Jiangnan University,Wuxi ,China"
            },
            {
                "name": "SHI Jingsong",
                "org": "School of Pharmaceutical Science,Jiangnan University,Wuxi ,China"
            }
        ],
        "venue": "Chinese Journal of Bioprocess Engineering",
        "year": 2013
    },
    "UdrhaSMI": {
        "id": "UdrhaSMI",
        "title": "Optimization of hydroxylating DHEA to 7alpha,15alpha-diOH-DHEA by compound mutation and fermentation optimization]",
        "abstract": "Combined with method of ketoconazole resistance screening, a 7alpha,15alpha-diOH-DHEA high-producing mutant Colletotrichum lini ST-1 was obtained by compound mutation of NTG and low energy N+ ion beam implantation. With the substrate concentration of 10 g/L DHEA, the molar yield of 7alpha,15alpha-diOH-DHEA reached 34.2%, increased by 46.2% than that of the original strain. Then we optimized the medium. First, Plackett-Burman design was used to evaluate the effects of medium components on molar yield of the product. Results show that glucose, yeast extract and MgSO4 x 7H2O were the important parameters for the biotransformation process. Subsequently, the path of steepest ascent was used to approach the optimal levels. To obtain the optimal levels, central composite design and response surface analysis were carried out. The optimal medium was as follows (g/L): glucose 26.34, yeast extract 12.15, corn flour 3.00, FeSO4 x 7H2O 0.015, MgSO4 x 7H2O 0.14, KH2PO4 0.90. Under the optimal conditions, the molar yield of 7alpha,15alpha-diOH-DHEA reached 49.3%, which was 44.2% higher than that of using the medium before optimization.",
        "keywords": [],
        "authors": [
            {
                "name": "Li Chuanpeng",
                "org": ""
            },
            {
                "name": "Li Hui",
                "org": ""
            },
            {
                "name": "Wu Yan",
                "org": ""
            },
            {
                "name": "Li Heng",
                "org": ""
            },
            {
                "name": "Zhang Rujin",
                "org": ""
            },
            {
                "name": "Zhang Zhengbin",
                "org": ""
            },
            {
                "name": "Shi Jinsong",
                "org": ""
            },
            {
                "name": "Xu Zhenghong",
                "org": ""
            }
        ],
        "venue": "Sheng wu gong cheng xue bao = Chinese journal of biotechnology",
        "year": 2014
    },
    "NJCrGRPG": {
        "id": "NJCrGRPG",
        "title": "Enhanced biotransformation of dehydroepiandrosterone to 3\u03b2,7\u03b1,15\u03b1-trihydroxy-5-androsten-17-one with Gibberella intermedia CA3-1 by natural oils addition.",
        "abstract": "Dihydroxylation of dehydroepiandrosterone (DHEA) is an essential step in the synthesis of many important pharmaceutical intermediates. However, the solution to the problem of low biohydroxylation conversion in the biotransformation of DHEA has yet to be found. The effects of natural oils on the course of dihydroxylation of DHEA to 3\u03b2,7\u03b1,15\u03b1-trihydroxy-5-androsten-17-one (7\u03b1,15\u03b1-diOH-DHEA) were studied. With rapeseed oil (2 %, v/v) addition, the bioconversion efficiency was improved, and the 7\u03b1,15\u03b1-diOH-DHEA yield was increased by 40.8 % compared with that of the control at DHEA concentration of 8.0 g/L. Meantime, the ratio of 7\u03b1,15\u03b1-diOH-DHEA to 7\u03b1-OH-DHEA was also increased by 4.5 times in the rapeseed oil-containing system. To explain the mechanism underlying the increase of 7\u03b1,15\u03b1-diOH-DHEA yield, the effects of rapeseed oil on the pH of the bioconversion system, the cell growth and integrity of Gibberella intermedia CA3-1, as well as the membrane composition were systematically studied. The addition of rapeseed oil enhanced the substrate dispersion and maintained the pH of the system during bioconversion. Cells grew better with favorable integrity. The fatty acid profile of G. intermedia cells revealed that rapeseed oil changed the cell membrane composition and improved cell membrane permeability for lipophilic substrates.",
        "keywords": [],
        "authors": [
            {
                "name": "Li Heng",
                "org": "School of Pharmaceutical Science, Jiangnan University, 1800 Lihu Avenue, 214122, Wuxi, People's Republic of China."
            },
            {
                "name": "Fu Zhenzhen",
                "org": ""
            },
            {
                "name": "Li Hui",
                "org": ""
            },
            {
                "name": "Zhang Xiaomei",
                "org": ""
            },
            {
                "name": "Shi Jinsong",
                "org": ""
            },
            {
                "name": "Xu Zhenghong",
                "org": ""
            }
        ],
        "venue": "Journal of industrial microbiology & biotechnology",
        "year": 2014
    },
    "Sxp0gZ09": {
        "id": "Sxp0gZ09",
        "title": "The efficient production of 3\u03b2,7\u03b1,15\u03b1-trihydroxy-5-androsten-17-one from dehydroepiandrosterone by Gibberella intermedia.",
        "abstract": "The biotransformation of dehydroepiandrosterone (DHEA) by Gibberella intermedia was investigated. The formation of the main products was monitored by high-performance liquid chromatography (HPLC). Products were purified and identified as 3\u03b2,7\u03b1-dihydroxy-5-androsten-17-one (7\u03b1-OH-DHEA) and 3\u03b2,7\u03b1,15\u03b1-trihydroxy-5-androsten-17-one (7\u03b1,15\u03b1-diOH-DHEA) using mass spectroscopy (MS) and nuclear magnetic resonance (NMR) analyses. 7\u03b1,15\u03b1-DiOH-DHEA is a key intermediate for the synthesis of pharmacologically active steroids. A biotransformation process was optimized to obtain a high concentration of 7\u03b1,15\u03b1-diOH-DHEA. The results showed the optimal biotransformation process under the following conditions: a culture medium containing 15 g/L glucose, 16 g/L yeast extract, 12 g/L corn steep liquor, and 0.15 g/L ferrous sulfate; an initial pH of 6.5; culture temperature of 30 \u00b0C; inoculum size of 4 %; 40 mL volume of the culture medium in 250 mL flasks; the addition of 1 % Tween 80 as co-solvent; and the transformation period of 78 h. After optimization, the molar yield of 7\u03b1,15\u03b1-diOH-DHEA from 5 g/L substrate DHEA was 77.4 %, which was increased by 115 % than the yield obtained in the original bioconversion process.",
        "keywords": [],
        "authors": [
            {
                "name": "Li Hui",
                "org": "School of Pharmaceutical Science, Jiangnan University, 1800 Lihu Avenue, 214122, Wuxi, People's Republic of China."
            },
            {
                "name": "Fu Zhenzhen",
                "org": ""
            },
            {
                "name": "Zhang Xiaomei",
                "org": ""
            },
            {
                "name": "Li Heng",
                "org": ""
            },
            {
                "name": "Shi Jinsong",
                "org": ""
            },
            {
                "name": "Xu Zhenghong",
                "org": ""
            }
        ],
        "venue": "Applied biochemistry and biotechnology",
        "year": 2014
    },
    "sBhHyi4Z": {
        "id": "sBhHyi4Z",
        "title": "Preparation and the chromatographic behavior analysis of low degree polymerization of Chitooligosaccharides components",
        "abstract": "Low- degree polymerization chitooligosaccharides( COS) were prepared with the chitosan hyrolized by chitosan enzymatic utilizing the ethanol precipitation method.A HPLC analysis method was also presented for COS with remarkable separation and high sensitivity based on Shodex NH2P-50 4E Column and acetonitrile- ammonia mobile phase as the gradient elution.The N-acetylated constituent in COS could be identified using UPLC-MS.The chromatographic behavior of COS was also studied. Results illustrated that the N- acetylated constituent in COS was the main reason for that chromatographic separation of chitosan is not in accordance with its polymerization degree,which was very important for analyzing and separating the constituents of chitosan.",
        "keywords": [
            "HPLC",
            "DP",
            "UPLC-MS",
            "COS"
        ],
        "authors": [
            {
                "name": "ZHU Yu-xia",
                "org": "Institute of Pharmaceutics,Jiangnan University,Wuxi ,China"
            },
            {
                "name": "LI Heng",
                "org": "Institute of Pharmaceutics,Jiangnan University,Wuxi ,China"
            },
            {
                "name": "CHEN Lie-huan",
                "org": "School of Marine Science & Technology,HuaiHai Institute of Technology,Lianyungang ,China"
            },
            {
                "name": "XU Zheng-hong",
                "org": "Institute of Pharmaceutics,Jiangnan University,Wuxi ,China"
            },
            {
                "name": "SHI Jin-song",
                "org": "Institute of Pharmaceutics,Jiangnan University,Wuxi ,China"
            }
        ],
        "venue": "Science and Technology of Food Industry",
        "year": 2013
    },
    "tFH3eNMA": {
        "id": "tFH3eNMA",
        "title": "Isolation,Identification,and Fermentation Optimization of a High Efficient Novel Alginate-degrading Strain",
        "abstract": "A high efficient novel alginate-degrading microorganism was isolated from rotten seaweed using sodium alginate as the sole carbon source.Based on the morphological,physiological characteristics and 16S rDNA sequence,the strain was identified as Isoptericola halotolerans WX.The optimized fermentation medium was composed of sodium alginate 6.0 g/L,tryptone 5.0 g/L,yeast extract 2.5 g/L,NaCl 25.0 g/L,MgSO4 2 mmol/L,CaCl2 0.5 mmol/L,KH2PO4 1 mmol/L,FeSO4 0.2 mmol/L,and MnSO4 0.3 mmol/L.The optimal culture condition was that the strain was cultured in 250 mL shake flasks containing 20 mL medium with shaking speed of 180 r/min and initial pH 8.0 at 25 \u2103 for 44 h.Besides,2 mmol/L Mg2+ and 0.2 mmol/L Fe2+ had remarkable effect on enzyme activity.Under the optimized conditions,the activity of alginate lyase was increased significantly from 32 U/mL to 432 U/mL,around 13-fold compared with the state without optimization.Additionally,Isoptericola halotolerans WX was demonstrated to possess the activity of amylase,which confers its extensive potential applications.",
        "keywords": [
            "fermentation optimization",
            "isolation",
            "alginate lyase",
            "amylase",
            "alginate oligosaccharides",
            "Isoptericola halotolerans"
        ],
        "authors": [
            {
                "name": "Wei Dan",
                "org": ""
            },
            {
                "name": "Dou Wen-fang",
                "org": ""
            },
            {
                "name": "Li Heng",
                "org": ""
            },
            {
                "name": "Li Hui",
                "org": ""
            },
            {
                "name": "Xu Zheng-hong",
                "org": ""
            },
            {
                "name": "Shi Jin-song",
                "org": ""
            }
        ],
        "venue": "Food and Fermentation Industries",
        "year": 2012
    },
    "Se2H0L71": {
        "id": "Se2H0L71",
        "title": "Screening and condition optimization of a strain for efficiently biotransformation of saponins in Dioscorea zingiberensis into diosgenin]",
        "abstract": "Diosgenin is an important raw material in steroid hormone and widely used in pharmaceutical industry. The traditional method for diosgenin production is acidolysis, which causes serious pollution. In order to obtain a cleaner and more efficient approach of diosgenin production, a strain of Gibberella intermedia WX12 (the sexual stage of Fusarium proliferatum) was screened from the strains deposited in our laboratory. This strain converted saponins in Dioscorea zingiberensis C.H. Wright (DZW) into diosgenin. The conversion medium was optimized by statistical experimental design. The optimized conversion medium was as follows (g/L): glucose 20.6, yeast extract 5.0, NaCl 1, K2PO4 3, ZnSO4 x 7H2O 1.5 and saponins 3. Under the optimal conditions, the yield of diosgenin achieved to (31 +/- 0.3) mg/g DZW, which was 3 times higher than that of the original medium.",
        "keywords": [
            "response surface method",
            "optimization",
            "strain screening",
            "diosgenin"
        ],
        "authors": [
            {
                "name": "Jiajia Zhang",
                "org": " School of Pharmaceutical Science,Jiangnan University,Wuxi ,Jiangsu,China"
            },
            {
                "name": "Hui Li",
                "org": " School of Pharmaceutical Science,Jiangnan University,Wuxi ,Jiangsu,China"
            },
            {
                "name": "Heng Li",
                "org": " School of Pharmaceutical Science,Jiangnan University,Wuxi ,Jiangsu,China"
            },
            {
                "name": "Zhenming Lu",
                "org": " School of Pharmaceutical Science,Jiangnan University,Wuxi ,Jiangsu,China"
            },
            {
                "name": "Jinsong Shi",
                "org": " School of Pharmaceutical Science,Jiangnan University,Wuxi ,Jiangsu,China"
            },
            {
                "name": "Zhenghong Xu",
                "org": " School of Pharmaceutical Science,Jiangnan University,Wuxi ,Jiangsu,China"
            }
        ],
        "venue": "Sheng wu gong cheng xue bao = Chinese journal of biotechnology",
        "year": 2013
    },
    "NrSjuHW0": {
        "id": "NrSjuHW0",
        "title": "Teaching Reform and Practice of Microbiology in the Biopharmaceutical Engineering",
        "abstract": "The pharmaceutical engineering discipline construction of Jiangnan University was based on the national key subject fermentation engineering.The drug design and production problems were studied and solved using biological means.The research of microorganisms,recombinant DNA and natural product extraction pharmaceutical engineering was carried out.In view of above characteristics,in order to achieve the purpose of today's society to develop technical expertise in both basic knowledge and practical skills,the theory and practice of teaching reform of microbiology course in the pharmaceutical engineering with biopharmaceutical process characteristics were focused on,which would lay the foundation for training a new generation of biopharmaceutical professional excellence engineer.",
        "keywords": [
            "teaching reform",
            "biopharmaceutical engineering",
            "microbiology"
        ],
        "authors": [
            {
                "name": "LI Hui",
                "org": "School of Medicine and Pharmaceutics,Jiangnan University,Jiangsu Wuxi ,China"
            },
            {
                "name": "LI Heng",
                "org": "School of Medicine and Pharmaceutics,Jiangnan University,Jiangsu Wuxi ,China"
            },
            {
                "name": "GENG Yan",
                "org": "School of Medicine and Pharmaceutics,Jiangnan University,Jiangsu Wuxi ,China"
            },
            {
                "name": "DOU Wen-fang",
                "org": "School of Medicine and Pharmaceutics,Jiangnan University,Jiangsu Wuxi ,China"
            },
            {
                "name": "SHI Jin-song",
                "org": "School of Medicine and Pharmaceutics,Jiangnan University,Jiangsu Wuxi ,China"
            },
            {
                "name": "XU Zheng-hong",
                "org": "School of Medicine and Pharmaceutics,Jiangnan University,Jiangsu Wuxi ,China"
            }
        ],
        "venue": "Guangzhou Chemical Industry",
        "year": 2012
    },
    "gGEzP656": {
        "id": "gGEzP656",
        "title": "Metagenomic technology and genome mining: emerging areas for exploring novel nitrilases.",
        "abstract": "Nitrilase is one of the most important members in the nitrilase superfamily and it is widely used for bioproduction of commodity chemicals and pharmaceutical intermediates as well as bioremediation of nitrile-contaminated wastes. However, its application was hindered by several limitations. Searching for new nitrilases and improving their application performances are the driving force for researchers. Genetic data resources in various databases are quite rich in post-genomic era. Besides, more than 99 % of microbes in the environment are unculturable. Metagenomic technology and genome mining are thus becoming burgeoning areas and provide unprecedented opportunities for searching more useful novel nitrilases due to the abundance of already existing but unexplored gene resources, namely uncharacterized genome information in the database and unculturable microbes in the natural environment. These techniques seem to be innovative and highly efficient. This study reviews the current status and future directions of metagenomics and genome mining in nitrilase exploration. Moreover, it discussed their utilization in coping with the challenges for nitrilase application. In the next several years, with the rapid development of nitrile biocatalysis, these two techniques would be bound to attract increasing attentions and even become a dominant trend for finding more novel nitrilases. Also, this review would provide guidance for exploitation of other commercially important enzymes.",
        "keywords": [],
        "authors": [
            {
                "name": "Gong Jin-Song",
                "org": "School of Pharmaceutical Science, Jiangnan University, Wuxi, 214122, People's Republic of China."
            },
            {
                "name": "Lu Zhen-Ming",
                "org": ""
            },
            {
                "name": "Li Heng",
                "org": ""
            },
            {
                "name": "Zhou Zhe-Min",
                "org": ""
            },
            {
                "name": "Shi Jin-Song",
                "org": ""
            },
            {
                "name": "Xu Zheng-Hong",
                "org": ""
            }
        ],
        "venue": "Applied microbiology and biotechnology",
        "year": 2013
    },
    "F5sLbfCB": {
        "id": "F5sLbfCB",
        "title": "Enhancement of steroid hydroxylation yield from dehydroepiandrosterone by cyclodextrin complexation technique.",
        "abstract": "The cyclodextrins (CDs) complexation technique was performed for the enhancement of hydroxylation yield from dehydroepiandrosterone (DHEA) by Colletotrichum lini ST-1. Using DHEA/methyl-\u03b2-cyclodextrin (M-\u03b2-CD) or DHEA/hydroxypropyl-\u03b2-cyclodextrin (HP-\u03b2-CD) inclusion complexes as substrate (10g/L), the hydroxylation yields were increased by 14.98% and 20.54% respectively, and the biotransformation course was shortened by 12h. X-ray diffractometry, differential scanning calorimetry, and phase solubility analyses showed an inclusion complex was formed between CDs and DHEA at a molar ratio of 1:1, which remarkably increased the solubility of DHEA, and then improved substrate biotransformation efficiency and hydroxylation yield. Meanwhile, results of thermodynamic parameters (\u0394G, \u0394H, \u0394S and Ks) analysis revealed the complexation process was spontaneous and DHEA/CDs inclusion complex was stable. Scanning electron microscopy and transmission electron microscopy showed that the enhancement of DHEA hydroxylation yield also depended on the improvement of cell permeability through interaction between cytomembrane and CDs. These results suggested that the CDs complexation technique was a promising method to enhance steroids hydroxylation yield by increasing steroids solubility and decreasing membrane resistance of substrate and product during biotransformation process.",
        "keywords": [
            "biotransformation",
            "cyclodextrin",
            "dhea"
        ],
        "authors": [
            {
                "name": "Wu Yan",
                "org": "School of Pharmaceutical Science, Jiangnan University, Wuxi 214122, People's Republic of China; School of Biotechnology, Jiangnan University, Wuxi 214122, People's Republic of China."
            },
            {
                "name": "Li Hui",
                "org": "School of Pharmaceutical Science, Jiangnan University, Wuxi 214122, People's Republic of China."
            },
            {
                "name": "Lu Zhen-Ming",
                "org": "School of Pharmaceutical Science, Jiangnan University, Wuxi 214122, People's Republic of China."
            },
            {
                "name": "Li Heng",
                "org": "School of Pharmaceutical Science, Jiangnan University, Wuxi 214122, People's Republic of China."
            },
            {
                "name": "Rao Zhi-Ming",
                "org": "School of Biotechnology, Jiangnan University, Wuxi 214122, People's Republic of China."
            },
            {
                "name": "Geng Yan",
                "org": "School of Pharmaceutical Science, Jiangnan University, Wuxi 214122, People's Republic of China."
            },
            {
                "name": "Shi Jin-Song",
                "org": "School of Pharmaceutical Science, Jiangnan University, Wuxi 214122, People's Republic of China."
            },
            {
                "name": "Xu Zheng-Hong",
                "org": "School of Pharmaceutical Science, Jiangnan University, Wuxi 214122, People's Republic of China."
            }
        ],
        "venue": "Steroids",
        "year": 2014
    },
    "YoRqTILd": {
        "id": "YoRqTILd",
        "title": "Screening, identification and culture optimization of a newly isolated aromatic nitrilase-producing bacterium--Pseudomonas putida CGMCC3830.",
        "abstract": "Microbial nitrilases have attracted increasing attention in nitrile hydrolysis for carboxylic acid production in recent years. A bacterium with nitrilase activity was isolated and identified as Pseudomonas putida CGMCC3830 based on its morphology, physiological and biochemical characteristics, as well as 16S rRNA gene sequence. The nitrilase production was optimized by varying culture conditions using the one-factor-at-a-time method and response surface methodology. Glycerol 13.54 g/L, tryptone 11.59 g/L, yeast extract 5.21 g/L, KH2PO4 1 g/L, NaCl 1 g/L, urea 1 g/L, initial pH 6.0 and culture temperature 30 degrees C were proved to be the optimal culture conditions. It resulted in the maximal nitrilase production of 36.12 U/mL from 2.02 U/mL. Investigations on substrate specificity demonstrate P. putida nitrilase preferentially hydrolyze aromatic nitriles. When applied in nicotinic acid synthesis, 2 mg/mL P. putida cells completely hydrolyzed 20.8 g/L 3-cyanopyridine into nicotinic acid in 90 min. The results indicated P. putida CGMCC3830 displayed potential for industrial production of nicotinic acid.",
        "keywords": [],
        "authors": [
            {
                "name": "Zhu Xiaoyan",
                "org": ""
            },
            {
                "name": "Gong Jinsong",
                "org": ""
            },
            {
                "name": "Li Heng",
                "org": ""
            },
            {
                "name": "Lu Zhenming",
                "org": ""
            },
            {
                "name": "Zhou Zhemin",
                "org": ""
            },
            {
                "name": "Shi Jinsong",
                "org": ""
            },
            {
                "name": "Xu Zhenghong",
                "org": ""
            }
        ],
        "venue": "Sheng wu gong cheng xue bao = Chinese journal of biotechnology",
        "year": 2014
    },
    "jvrtw3JI": {
        "id": "jvrtw3JI",
        "title": "Improving the catalytic potential and substrate tolerance of Gibberella intermedia nitrilase by whole-cell immobilization.",
        "abstract": "Comparative studies of immobilized and free cells of Gibberella intermedia CA3-1 in bioconversion of 3-cyanopyridine to nicotinic acid were performed. Entrapping method was chosen based on the advantages in enzymatic activity recovery, mechanical strength and preparation procedure. Four entrapment matrices were investigated and sodium alginate was screened to be the most suitable material. Maximal nitrilase activity of alginate immobilized cells was obtained under conditions of 2 % alginate, 0.6 % CaCl2, 0.4 g cell/g alginate, 1.8 mm bead size. The immobilized cells showed excellent substrate tolerance even when the 3-cyanopyridine concentration was 700 mM. The half-lives of immobilized cells at 30, 40 and 50 \u00b0C were 315, 117.5 and 10.9 h, respectively, correspondingly 1.4, 1.6 and 1.7-fold compared with that of the free cells. Efficient reusability of immobilized cells up to 28 batches was achieved and 205.7 g/(g dcw) nicotinic acid was obtained with 80.55 % enzyme activity preserved.",
        "keywords": [],
        "authors": [
            {
                "name": "Li Heng",
                "org": "School of Pharmaceutical Science, Jiangnan University, 1800 Lihu Avenue, Wuxi, 214122, People's Republic of China."
            },
            {
                "name": "Yang Tao",
                "org": ""
            },
            {
                "name": "Gong Jin-Song",
                "org": ""
            },
            {
                "name": "Xiong Lei",
                "org": ""
            },
            {
                "name": "Lu Zhen-Ming",
                "org": ""
            },
            {
                "name": "Li Hui",
                "org": ""
            },
            {
                "name": "Shi Jin-Song",
                "org": ""
            },
            {
                "name": "Xu Zheng-Hong",
                "org": ""
            }
        ],
        "venue": "Bioprocess and biosystems engineering",
        "year": 2015
    },
    "T00NaMgx": {
        "id": "T00NaMgx",
        "title": "Nitrilases in nitrile biocatalysis: recent progress and forthcoming research.",
        "abstract": "Over the past decades, nitrilases have drawn considerable attention because of their application in nitrile degradation as prominent biocatalysts. Nitrilases are derived from bacteria, filamentous fungi, yeasts, and plants. In-depth investigations on their natural sources function mechanisms, enzyme structure, screening pathways, and biocatalytic properties have been conducted. Moreover, the immobilization, purification, gene cloning and modifications of nitrilase have been dwelt upon. Some nitrilases are used commercially as biofactories for carboxylic acids production, waste treatment, and surface modification. This critical review summarizes the current status of nitrilase research, and discusses a number of challenges and significant attempts in its further development. Nitrilase is a significant and promising biocatalyst for catalytic applications.",
        "keywords": [
            "bacteria",
            "metals",
            "biotechnology",
            "biocatalysis"
        ],
        "authors": [
            {
                "name": "Gong Jin-Song",
                "org": "The Key Laboratory of Industrial Biotechnology, Ministry of Education, Jiangnan University, Wuxi, People's Republic of China."
            },
            {
                "name": "Lu Zhen-Ming",
                "org": ""
            },
            {
                "name": "Li Heng",
                "org": ""
            },
            {
                "name": "Shi Jin-Song",
                "org": ""
            },
            {
                "name": "Zhou Zhe-Min",
                "org": ""
            },
            {
                "name": "Xu Zheng-Hong",
                "org": ""
            }
        ],
        "venue": "Microbial cell factories",
        "year": 2012
    },
    "aB3nwBsK": {
        "id": "aB3nwBsK",
        "title": "Exploration of Curricula Collocation and Teaching Method in Cell Biology",
        "abstract": "Cell Biology was one of the leading subjects in life sciences and one of the important basic course of pharmaceutical engineering undergraduate.In order to improve the teaching quality,it was urged to push the progress of curricula collocation and teaching methods.Now there were some teaching shortcomings including too much knowledge and less teaching time,lacking interaction,and lower ratio of experimental courses.Based on the actuality,a series of teaching innovation were carried out to improving the curriculum integration,participation and harmonious.It was proved that the teaching effect was improved by interesting the undergraduates.",
        "keywords": [
            "Cell Biolody",
            "pharmaceutical engineering",
            "teaching reform"
        ],
        "authors": [
            {
                "name": "GENG Yan",
                "org": "School of Medicine and Pharmaceutics,Jiangnan University,Jiangsu Wuxi ,China"
            },
            {
                "name": "XU Hong-yu",
                "org": "School of Medicine and Pharmaceutics,Jiangnan University,Jiangsu Wuxi ,China"
            },
            {
                "name": "LI Hui",
                "org": "School of Medicine and Pharmaceutics,Jiangnan University,Jiangsu Wuxi ,China"
            },
            {
                "name": "LI Heng",
                "org": "School of Medicine and Pharmaceutics,Jiangnan University,Jiangsu Wuxi ,China"
            },
            {
                "name": "LU Zhen-ming",
                "org": "School of Medicine and Pharmaceutics,Jiangnan University,Jiangsu Wuxi ,China"
            },
            {
                "name": "SHI Jin-song",
                "org": "School of Medicine and Pharmaceutics,Jiangnan University,Jiangsu Wuxi ,China"
            },
            {
                "name": "XU Zheng-hong",
                "org": "School of Medicine and Pharmaceutics,Jiangnan University,Jiangsu Wuxi ,China"
            }
        ],
        "venue": "Guangzhou Chemical Industry",
        "year": 2012
    },
    "W2wizwPS": {
        "id": "W2wizwPS",
        "title": "Study on Preparation of Crystalline AAKG from L-Arginine Fermentation Broth",
        "abstract": "AAKG(L-arginine-alpha-ketoglutarate) is a functional product of amino acid salts with increasing sales in the current international market.The usual form of the product is hybrid rather than crystalline.Herein crystalline AAKG was prepared directly used L-arginine fermentation broth as the raw material and then complexation by adding \u03b1-ketoglutarate.The main process steps and control parameters were described as follows.Firstly the L-Arginine fermentation broth was flocculated and filtrated,and then concentrated under reduced pressure to a concentration of 1.0 mol/L.Then it was complexated by adding equimolar \u03b1-KG and further concentrated under reduced pressure so that the concentration of AAKG reached 1.5 mol/L.Crude crystals were obtained after the concentrate was cooled at a rate of 2 \u2103/h and ultimately crystallized at 10 \u2103 for 24h,and then it was recrystallized under the same conditions.The purity of AAKG was 99.2%.The ratio of L-Arg to \u03b1-KG was 1\u2236 1.02.The total recovery ratio was 62.9%.",
        "keywords": [
            "alpha-ketoglutarate",
            "L-arginine-alpha-ketoglutarate",
            "crystallize",
            "L-arginine"
        ],
        "authors": [
            {
                "name": "Li Qi-qian",
                "org": "Shool of Medicine and Pharmaceutics,Jiangnan University,Wuxi ,China"
            },
            {
                "name": "Li Heng",
                "org": "Shool of Medicine and Pharmaceutics,Jiangnan University,Wuxi ,China"
            },
            {
                "name": "Lu Zhen-ming",
                "org": "Shool of Medicine and Pharmaceutics,Jiangnan University,Wuxi ,China"
            },
            {
                "name": "Xu Hong-yu",
                "org": "Shool of Medicine and Pharmaceutics,Jiangnan University,Wuxi ,China"
            },
            {
                "name": "Fang Jia-mao",
                "org": "Guangdong Huanxi Biological Technology Co.,Ltd,Puning ,China"
            },
            {
                "name": "Xu Zheng-hong",
                "org": "Shool of Medicine and Pharmaceutics,Jiangnan University,Wuxi ,China"
            },
            {
                "name": "Sun Zhi-hao",
                "org": "Shool of Medicine and Pharmaceutics,Jiangnan University,Wuxi ,China"
            },
            {
                "name": "Shi Jin-song",
                "org": "Shool of Medicine and Pharmaceutics,Jiangnan University,Wuxi ,China"
            }
        ],
        "venue": "Food and Fermentation Industries",
        "year": 2012
    },
    "xb0NgfYP": {
        "id": "xb0NgfYP",
        "title": "Differentiation analysis of volatile constituents in the Pit Muds from different parts of Chinese Liquor cellar",
        "abstract": "The volatile constituents in the pit muds from different parts of Luzhou Laojiao cellar with 50 years were detected and analyzed.Gas chromatograph-mass spectrum(GC-MS) coupled with head-space solid phase microextraction(HS-SPME) were employed.65 volatile compounds were identified,mainly were esters,alcohols,acids,aldehydes,ketones and phenols.There were only small differences in the compounds of alcohol,aldehyde,ketone and phenol between the cellar wall mud and the bottom cellar mud,while significant discrepancies in acids and easters.Hexanoic acid,butyl hexanoate and hexyl hexanoate were the characteristic components in the cellar wall mud,while methyl caproate in the bottom cellar mud.",
        "keywords": [
            "gas chromatograph-mass spectrum",
            "pit mud",
            "head-space solid phase microextraction",
            "volatile constituents"
        ],
        "authors": [
            {
                "name": "Li Heng",
                "org": "School of Pharmaceutical Science,Jiangnan University,Wuxi ,China"
            },
            {
                "name": "Sun Xia-bing",
                "org": "School of Pharmaceutical Science,Jiangnan University,Wuxi ,China"
            },
            {
                "name": "Lu Zhen-ming",
                "org": "School of Pharmaceutical Science,Jiangnan University,Wuxi ,China;Tianjin Key Laboratory for Industrial Biological Systems and Bioprocessing Engineering, Tianjin Institute of Industrial Biotechnology,Chinese Academy of Sciences,Tianjin,,China"
            },
            {
                "name": "Wang Song-tao",
                "org": "National Engineering Research Center of Solid-State Brewing,Luzhou ,China"
            },
            {
                "name": "Shen Cai-hong",
                "org": "National Engineering Research Center of Solid-State Brewing,Luzhou ,China"
            },
            {
                "name": "Xu Zheng-hong",
                "org": "School of Pharmaceutical Science,Jiangnan University,Wuxi ,China;National Engineering Research Center of Solid-State Brewing,Luzhou ,China;Tianjin Key Laboratory for Industrial Biological Systems and Bioprocessing Engineering, Tianjin Institute of Industrial Biotechnology,Chinese Academy of Sciences,Tianjin,,China"
            },
            {
                "name": "Shi Jin-song",
                "org": "School of Pharmaceutical Science,Jiangnan University,Wuxi ,China;National Engineering Research Center of Solid-State Brewing,Luzhou ,China"
            }
        ],
        "venue": "Food and Fermentation Industries",
        "year": 2013
    },
    "B9Dl7rmp": {
        "id": "B9Dl7rmp",
        "title": "The effected pressure of bile duct by pre-placement of ENBD tube and primary suture of common bile duct",
        "abstract": "\u3010Objective\u3011To observe the change of the bile duct pressure after pre-placement of ENBD tube and primary suture of common bile duct.\u3010Methods\u301118 choledocholithiasis patients (studied group) admitted to our hospital from Jan 2006 to Dec 2007 and primary suture after the common bile duct (CBD) incision andexploration done,10 received the traditional T tube drainage choledocholithiasis patients as control (control group). The bile duct pres-sure measured by U shaped tube connected to the ENBD tube or the T tube before and after dining respectively during 1 to 7 days after the operation. \u3010Results\u3011The drained bile of studied group less than the control group,especially at the third and forth days (P <0.05),and mean biliary pressure of each day were no significant different between the two groups(P >0.05),the elevatory level of the bile duct pressure of studied group caused by dining was higher than the control group at the seventh day post-operation (P <0.05). \u3010Conclusion\u3011Pre-placement of ENBD tube and primary suture of common bile duct could decrease the bile losed quantity and not change the bile duct pressure compared to the traditional T tube drainage,which could be beneficial to the choledocholithiasis patients possibly.",
        "keywords": [
            "pressure",
            "common bile duc",
            "primary suture",
            "ENBD"
        ],
        "authors": [
            {
                "name": "JIAN Zhiyuan",
                "org": "Department of Hepatic and Biliary Surgery,Taihe Hospital,Yunyang Medical College,Shiyan,Hubei ,P.R.China"
            },
            {
                "name": "ZENG Shaobo",
                "org": "Department of Hepatic and Biliary Surgery,Taihe Hospital,Yunyang Medical College,Shiyan,Hubei ,P.R.China"
            },
            {
                "name": "ZHOU Ping",
                "org": "Department of Hepatic and Biliary Surgery,Taihe Hospital,Yunyang Medical College,Shiyan,Hubei ,P.R.China"
            },
            {
                "name": "LI Heng",
                "org": "Department of Hepatic and Biliary Surgery,Taihe Hospital,Yunyang Medical College,Shiyan,Hubei ,P.R.China"
            },
            {
                "name": "JIANG Bin",
                "org": "Department of Hepatic and Biliary Surgery,Taihe Hospital,Yunyang Medical College,Shiyan,Hubei ,P.R.China"
            },
            {
                "name": "LAN Mingyin",
                "org": "Department of Hepatic and Biliary Surgery,Taihe Hospital,Yunyang Medical College,Shiyan,Hubei ,P.R.China"
            }
        ],
        "venue": "China Journal of Modern Medicine",
        "year": 2009
    },
    "GCPyaTum": {
        "id": "GCPyaTum",
        "title": "Relationship between p38MAPK activity and apoptosis during drug resistance of breast carcinoma cell lines",
        "abstract": "Objective To investigate the relationship between p38MAPK activity and cell apoptosis and the effect of p38MAPK signal transduction pathway during drug resistance of breast carcinoma cell lines.Methods Flow cytometry(FCM)was used to analyze the effect of p38MAPK inhibitor SB203580 on the apoptosis of MCF-7/ADM cell,a drug resistant human breast cancer cell.The inhibition concentration 50%(IC50)of adriamycin on MCF-7/ADM was determined by MTT method in vitro.The MDR-1 mRNA level and p38MAPK protein expression in each group were detected by RT-PCR and Western Blot,respectively.Results After SB203580 action for 24 hours,the apoptosis rate of MCF-7/ADM was(26.73\u00b14.90)%,which was significantly lower than that of the control group and the untreated group(F=143.80,P<0.001).The relative reverse rate of the sensitivity of MCF-7/ADM to adriamycin in the SB203580 treated group was 68.45%.The p38MAPK protein(F=685.42,P<0.001)and MDR-1 mRNA expression(F=913 9.24,P<0.001)after 24-hour SB203580 action were markedly lower than the control group and the untreated group.Conclusion p38MAPK signal pathway plays an important role in drug resistance of breast carcinoma cell.p38MAPK can protect MCF-7/ADM cells from apoptosis,and blocking the p38MAPK signal pathway can increase the apoptosis in drug resistant breast carcinoma cell lines.",
        "keywords": [
            "Multidrug resistance",
            "Breast carcinoma",
            "Cell apoptosis",
            "p38MAPK"
        ],
        "authors": [
            {
                "name": "ZENG Shao-bo",
                "org": ".General Surgery of Taihe Hospital,Yunyang Medical College,Shiyan ,China"
            },
            {
                "name": "LAN Ming-yin",
                "org": ".General Surgery of Taihe Hospital,Yunyang Medical College,Shiyan ,China"
            },
            {
                "name": "JIAN Zhi-yuan",
                "org": ".General Surgery of Taihe Hospital,Yunyang Medical College,Shiyan ,China"
            },
            {
                "name": "LI Heng",
                "org": ".General Surgery of Taihe Hospital,Yunyang Medical College,Shiyan ,China"
            },
            {
                "name": "YAN Bin",
                "org": ".General Surgery of Taihe Hospital,Yunyang Medical College,Shiyan ,China"
            },
            {
                "name": "ZHANG Min",
                "org": ".General Surgery of Taihe Hospital,Yunyang Medical College,Shiyan ,China"
            },
            {
                "name": "ZHOU Meng",
                "org": ".General Surgery of Taihe Hospital,Yunyang Medical College,Shiyan ,China"
            },
            {
                "name": "JIANG Bin",
                "org": ".General Surgery of Taihe Hospital,Yunyang Medical College,Shiyan ,China"
            }
        ],
        "venue": "Chinese Journal of Breast Disease(Electronic Edition)",
        "year": 2009
    },
    "u40z5fYw": {
        "id": "u40z5fYw",
        "title": "Diagnosis and treatment of unsuspected gallbladder carcinoma during LC",
        "abstract": "[Objective] To explore the diagnosis and treatment of unsuspected gallbladder carcinoma(UGC) during operating laparoscopic cholecystectomy(LC). [Methods] The clinical data of 5 cases with UGC in 1 330 cases with LC was reviewed retrospectively. [Results] Intraoperatively in 128 cases there was the suspicion of adenocarcinoma and frozen sections were performed. In four of them the diagnosis of adenocarcinoma was confirmed. One with stage\u2162 refused reoperation, In three of them the procedure was converted to open with radical surgery. Two with stage\u2161 died in 25 months and 13 months respectively. One with stage\u2162 died in 8 months. Of the remaining 1 203 patients, one was diagnosed postoperatively at the pathologic examination. He was peformed by LC alone three years ago, is alive to date. [Conclusion] Gallbladder cancer runs a short course, with a poor prognosis. The use of a meticulous laparoscopic technique seems to be important for the avoidance of port site metastases(PSM). It is an effective way to choose timely a second or converted open radical surery for prolonging the survival of the UGC.",
        "keywords": [
            "cholecystectomy",
            "laparoscopy",
            "gallbladder neoplasm"
        ],
        "authors": [
            {
                "name": "FU Ying-feng",
                "org": "Department of General Surgery, Taihe Hospital, Yunyang Medical College, Shiyan,, Hubei , P.R.China"
            },
            {
                "name": "LI Heng",
                "org": "Department of General Surgery, Taihe Hospital, Yunyang Medical College, Shiyan,, Hubei , P.R.China"
            },
            {
                "name": "LAN Ming-yin",
                "org": "Department of General Surgery, Taihe Hospital, Yunyang Medical College, Shiyan,, Hubei , P.R.China"
            },
            {
                "name": "JIANG Bin",
                "org": "Department of General Surgery, Taihe Hospital, Yunyang Medical College, Shiyan,, Hubei , P.R.China"
            },
            {
                "name": "DI Mao-jun",
                "org": "Department of General Surgery, Taihe Hospital, Yunyang Medical College, Shiyan,, Hubei , P.R.China"
            },
            {
                "name": "ZHOU Meng",
                "org": "Department of General Surgery, Taihe Hospital, Yunyang Medical College, Shiyan,, Hubei , P.R.China"
            }
        ],
        "venue": "China Journal of Endoscopy",
        "year": 2005
    },
    "Ywgyv6Iu": {
        "id": "Ywgyv6Iu",
        "title": "Lymphatic Mapping,Sentinel Node Biopsy and Micro-metastasis Detection in the Patients with Colorectal Cancer and their Clinical Significance",
        "abstract": "Objectives To identify the sentinel lymph nodes(SLN)in patients with colorectal cancer and evaluate their clinical significance.Methods Sixty patients with colorectal cancer underwent lymphatic mapping using methylene blue staining,the SLN was identified and removed,the micro-metastases in sentinel lymph node were also detected with HE and immunohistochemical staining technique.Results Fifty-four SLN were successfully identifed in sixty patients,with a detection rate 90.0%,higher than that of control group;thirty-six positive SLN were dectected by HE staining,six micro-metastases in Sentinel lymph node were found in eighteen negative SLN with Cytokeratin 20 immuno-histochemical staining.Conclusion The success rate achieved by combining methylene blue staining and cytokeratin 20 immunohistochemical staining is higher than that by using either technique alone;immunohistochemical assay is a sensitive way to detect micrometastases in lymph nodes,and this may have clinical significance for the treatment of colorectal cancer.",
        "keywords": [
            "Sentinel lymph node",
            "Lymph nodes trace",
            "Colorectal cancer",
            "Micrometastasis"
        ],
        "authors": [
            {
                "name": "ZHANG Min",
                "org": "~1Department of General Surgery,Zhongnan Hospital,Wuhan University,Wuhan,Hubei ;~2Department of General Surgery,Taihe Hospital,Yunyang Medical College,Shiyan,Hubei ,China"
            },
            {
                "name": "TAN Zui",
                "org": "~1Department of General Surgery,Zhongnan Hospital,Wuhan University,Wuhan,Hubei "
            },
            {
                "name": "JIAN Zhi-yuan",
                "org": "~2Department of General Surgery,Taihe Hospital,Yunyang Medical College,Shiyan,Hubei ,China"
            },
            {
                "name": "JIANG Bin",
                "org": "~2Department of General Surgery,Taihe Hospital,Yunyang Medical College,Shiyan,Hubei ,China"
            },
            {
                "name": "LAN Ming-yin",
                "org": "~2Department of General Surgery,Taihe Hospital,Yunyang Medical College,Shiyan,Hubei ,China"
            },
            {
                "name": "ZENG Shao-bo",
                "org": "~2Department of General Surgery,Taihe Hospital,Yunyang Medical College,Shiyan,Hubei ,China"
            },
            {
                "name": "LI Heng",
                "org": "~2Department of General Surgery,Taihe Hospital,Yunyang Medical College,Shiyan,Hubei ,China"
            },
            {
                "name": "WANG Geng",
                "org": "~2Department of General Surgery,Taihe Hospital,Yunyang Medical College,Shiyan,Hubei ,China"
            }
        ],
        "venue": "Journal of Yunyang Medical College",
        "year": 2006
    },
    "HG7KO9jd": {
        "id": "HG7KO9jd",
        "title": "Therapeutic Value of Different Chemotherapy Route on the Advanced Pancreatic Carcinoma",
        "abstract": "Objective To evaluate the therapeutic value of different chemotherapy route on the advanced pancreatic carcinoma.Methods Twelve cases were given intravenous chemotherapy,13 cases were given regional arterial chemotherapy,17 cases were given regional arterial chemotherapy combined with intravenous chemotherapy,the clinical beneficial response,objective response,side effects and survival time of all the patients were analyzed.Results The clinical beneficial response rates of three groups were 25.0%,61.5% and 76.5%,respectively(P<0.05);the effective rates were 33.3%,46.2% and 64.7%,respectively(P>0.05);there were 3,1,1 cases demonstrating serious adverse reaction in three groups,respectively.The median survival time were 8.0,9.0 and 11.5 months,respectively(P<0.05).Conclusion Regional arterial chemotherapy combined with intravenous chemotherapy could enhance the clinical beneficial response rate and effectively prolong the survival time of patients with advanced pancreatic carcinoma.",
        "keywords": [
            "Pancreatic carcinoma",
            "Chemotherapy",
            "Regional perfusion"
        ],
        "authors": [
            {
                "name": "JIAN Zhi-yuan",
                "org": "Department of Hepatobiliary Surgery,Taihe Hospital,Yunyang Medical College,Shiyan,Hubei ,China"
            },
            {
                "name": "ZENG Shao-bo",
                "org": "Department of Hepatobiliary Surgery,Taihe Hospital,Yunyang Medical College,Shiyan,Hubei ,China"
            },
            {
                "name": "LAN Ming-yin",
                "org": "Department of Hepatobiliary Surgery,Taihe Hospital,Yunyang Medical College,Shiyan,Hubei ,China"
            },
            {
                "name": "JIANG Bin",
                "org": "Department of Hepatobiliary Surgery,Taihe Hospital,Yunyang Medical College,Shiyan,Hubei ,China"
            },
            {
                "name": "LI Heng",
                "org": "Department of Hepatobiliary Surgery,Taihe Hospital,Yunyang Medical College,Shiyan,Hubei ,China"
            },
            {
                "name": "YAN Bin",
                "org": "Department of Hepatobiliary Surgery,Taihe Hospital,Yunyang Medical College,Shiyan,Hubei ,China"
            },
            {
                "name": "ZHANG Min",
                "org": "Department of Hepatobiliary Surgery,Taihe Hospital,Yunyang Medical College,Shiyan,Hubei ,China"
            }
        ],
        "venue": "Journal of Yunyang Medical College",
        "year": 2009
    },
    "AqmvGLh2": {
        "id": "AqmvGLh2",
        "title": "Modeling uncertain activity duration by fuzzy number and discrete-event simulation",
        "abstract": "",
        "keywords": [
            "probability distribution",
            "fuzzy set theory",
            "fuzzy number",
            "simulation experiment",
            "discrete event simulation"
        ],
        "authors": [
            {
                "name": "Hong Zhang",
                "org": ""
            },
            {
                "name": "C. M. Tam",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            }
        ],
        "venue": "European Journal of Operational Research",
        "year": 2005
    },
    "WA27BLXE": {
        "id": "WA27BLXE",
        "title": "Particle Swarm Optimization for Preemptive Scheduling under Break and Resource-Constraints",
        "abstract": "",
        "keywords": [
            "construction management",
            "preemptive scheduling",
            "optimization",
            "scheduling"
        ],
        "authors": [
            {
                "name": "Hong Zhang",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "C. M. Tam",
                "org": ""
            }
        ],
        "venue": "Journal of Construction Engineering and Management-asce",
        "year": 2006
    },
    "JqLjc9Zj": {
        "id": "JqLjc9Zj",
        "title": "Fuzzy discrete-event simulation for modeling uncertain activity duration",
        "abstract": "",
        "keywords": [
            "probability distribution",
            "simulation experiment",
            "simulation",
            "fuzzy logic",
            "construction industry",
            "fuzzy set theory",
            "discrete event simulation"
        ],
        "authors": [
            {
                "name": "Hong Zhang",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "C. M. Tam",
                "org": ""
            }
        ],
        "venue": "Engineering, Construction and Architectural Management",
        "year": 2004
    },
    "RGHGbItm": {
        "id": "RGHGbItm",
        "title": "Modeling Time-Constraints in Construction Operations through Simulation",
        "abstract": "Construction operations often face time constraints that influence the execution of activities, which are not addressed enough when modeling through general discrete-event simulation. This paper describes a simulation-based methodology to handle the time constraints including the cyclical break, preemption, and overtime use. In consideration of the variable number of breaks or variable break duration for different activities, an algorithm to determine the execution of the time-constrained activities is proposed, in which the concepts of time cycle and time window are introduced. The proposed algorithm is incorporated with an activity scanning simulation strategy to develop a construction simulation for modeling the time-constrained construction operations. Some examples are presented to illustrate and validate the algorithm, and highlight the effectiveness of the developed construction simulation. The study provides an alternative to improve construction simulation in modeling of the time-constrained construction operations and is expected to assist researchers or practitioners at analyzing or planning construction operations.",
        "keywords": [
            "constraints",
            "construction management",
            "simulation",
            "time factors",
            "stress analysis",
            "simulation model",
            "implementation",
            "activity",
            "modeling",
            "algorithms"
        ],
        "authors": [
            {
                "name": "Hong Zhang",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Ming Lu",
                "org": ""
            }
        ],
        "venue": "Journal of Construction Engineering and Management-asce",
        "year": 2008
    },
    "vu93hNXm": {
        "id": "vu93hNXm",
        "title": "Activity Object-Oriented Simulation Strategy for Modeling Construction Operations",
        "abstract": "",
        "keywords": [
            "computer languages",
            "control systems",
            "object oriented languages",
            "construction management",
            "simulation",
            "object oriented programming"
        ],
        "authors": [
            {
                "name": "Hong Zhang",
                "org": ""
            },
            {
                "name": "C. M. Tam",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            }
        ],
        "venue": "Journal of Computing in Civil Engineering",
        "year": 2005
    },
    "MeyyN3Qt": {
        "id": "MeyyN3Qt",
        "title": "Heuristic scheduling of resource-constrained, multiple-mode and repetitive projects",
        "abstract": "",
        "keywords": [
            "project scheduling",
            "scheduling",
            "heuristic algorithm"
        ],
        "authors": [
            {
                "name": "Hong Zhang",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "C. M. Tam",
                "org": ""
            }
        ],
        "venue": "Construction Management and Economics",
        "year": 2006
    },
    "AkxZAMXE": {
        "id": "AkxZAMXE",
        "title": "Permutation-Based Particle Swarm Optimization for Resource-Constrained Project Scheduling",
        "abstract": "",
        "keywords": [
            "construction management",
            "project scheduling",
            "optimization",
            "scheduling"
        ],
        "authors": [
            {
                "name": "Hong Zhang",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "C. M. Tam",
                "org": ""
            }
        ],
        "venue": "Journal of Computing in Civil Engineering",
        "year": 2006
    },
    "Pak5siJD": {
        "id": "Pak5siJD",
        "title": "Particle swarm optimization for resource-constrained project scheduling",
        "abstract": "This paper introduces the particle swarm optimization (PSO)-based approach to resolve the resource-constrained project scheduling problem (RCPSB) with the objective of minimizing project duration. Activities priorities for scheduling are represented by particles and a parallel scheme is utilized to transform the particle-represented priorities to a feasible schedule according to the precedence and resource constraints so as to be evaluated. Then the framework of the PSO scheme for the RCPSB is developed. Computational analyses are provided so as to investigate the performance of the PSO-based approach for the RCPSB. The study aims at developing an alternative and efficient optimization methodology for solving the RCPSB and opening the application of PSO to the optimization issues for construction project management.",
        "keywords": [
            "priority-based scheduling",
            "resource-constrained project scheduling",
            "managing projects",
            "particle swarm optimization",
            "construction industry",
            "project scheduling"
        ],
        "authors": [
            {
                "name": "Hong Zhang",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "C.M. Tam",
                "org": ""
            }
        ],
        "venue": "International Journal of Project Management",
        "year": 2006
    },
    "T7MFeOMv": {
        "id": "T7MFeOMv",
        "title": "Particle Swarm Optimization-Supported Simulation for Construction Operations",
        "abstract": "",
        "keywords": [
            "stochastic processes",
            "statistics",
            "stochastic model",
            "performance measurement",
            "particles",
            "optimization",
            "construction management",
            "simulation",
            "confidence intervals",
            "efficiency",
            "planning"
        ],
        "authors": [
            {
                "name": "Hong Zhang",
                "org": ""
            },
            {
                "name": "C. M. Tam",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Jonathan Jingsheng Shi",
                "org": ""
            }
        ],
        "venue": "Journal of Construction Engineering and Management-asce",
        "year": 2006
    },
    "sXRvVQzo": {
        "id": "sXRvVQzo",
        "title": "Multimode Project Scheduling Based on Particle Swarm Optimization",
        "abstract": "",
        "keywords": [
            "resource allocation",
            "particle swarm optimization",
            "project scheduling",
            "project management",
            "methodology",
            "construction industry",
            "optimization"
        ],
        "authors": [
            {
                "name": "Hong Zhang",
                "org": ""
            },
            {
                "name": "C. M. Tam",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            }
        ],
        "venue": "Comp.-Aided Civil and Infrastruct. Engineering",
        "year": 2006
    },
    "5Vwuzcun": {
        "id": "5Vwuzcun",
        "title": "Multi-objective particle swarm optimization for construction time-cost tradeoff problems",
        "abstract": "",
        "keywords": [
            "construction methods",
            "multi-objective optimization",
            "particle swarm optimization (pso)",
            "time-cost tradeoff",
            "multi objective optimization"
        ],
        "authors": [
            {
                "name": "Hong Zhang",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            }
        ],
        "venue": "Construction Management and Economics",
        "year": 2010
    },
    "06zesvmY": {
        "id": "06zesvmY",
        "title": "(5R)-5-hydroxytriptolide ameliorates anti-glomerular basement membrane glomerulonephritis in NZW mice by regulating Fc|[gamma]| receptor signaling",
        "abstract": "(5R)-5-hydroxytriptolide (LLDT-8) is a novel triptolide analog that has been identified as a promising candidate for treating autoimmune diseases and has been shown to be effective in treating murine collagen-induced arthritis and lupus nephritis. In the present study, we investigated the therapeutic effect and possible mechanism of action of LLDT-8 in a murine anti-glomerular basement membrane (GBM) glomerulonephritis model. NZW mice were injected with rabbit anti-GBM serum (500 \u03bcL, ip). The mice were orally treated with LLDT-8 (0.125 mg/kg, every other day) or a positive control prednisolone (2 mg/kg every day) for 14 d. Blood and urine samples as well as spleen and kidney tissues were collected for analyses. LLDT-8 treatment did not affect the generation of mouse anti-rabbit antibodies. LLDT-8 significantly reversed established proteinuria, improved renal histopathology and attenuated renal dysfunction in glomerulonephritis mice. Furthermore, LLDT-8 inhibited inflammation in the kidney evidenced by significantly decreasing C3 and IgG deposition, reducing the levels of the pathogenic cytokines TNF-\u03b1, IL-6, IL-17, and IFN-\u03b3, and reducing related chemokine expression and leukocyte infiltration in kidneys. Moreover, LLDT-8 treatment significantly increased the expression of Fc\u03b3RIIB in the kidney and spleen. In addition, the treatment restored the reduced expression of Fc\u03b3RIIB on the surface of kidney effector cells, CD11b+ cells, and interfered with Fc\u03b3R-dependent signaling, especially Fc\u03b3RIIB-mediated downstream kinases, such as BTK. These results demonstrate that LLDT-8 ameliorates anti-GBM glomerulonephritis by regulating the Fc\u03b3 receptor signaling.",
        "keywords": "",
        "authors": [
            {
                "name": "Qing Qi",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Ze-min Lin",
                "org": ""
            },
            {
                "name": "Xiao-qian Yang",
                "org": ""
            },
            {
                "name": "Feng-hua Zhu",
                "org": ""
            },
            {
                "name": "Yu-ting Liu",
                "org": ""
            },
            {
                "name": "Mei-juan Shao",
                "org": ""
            },
            {
                "name": "Lu-yao Zhang",
                "org": ""
            },
            {
                "name": "Yan-sheng Xu",
                "org": ""
            },
            {
                "name": "Yu-xi Yan",
                "org": ""
            },
            {
                "name": "Lan-lan Sun",
                "org": ""
            },
            {
                "name": "Shi-jun He",
                "org": ""
            },
            {
                "name": "Wei Tang",
                "org": ""
            },
            {
                "name": "Jian-ping Zuo",
                "org": ""
            }
        ],
        "venue": "Acta Pharmacologica Sinica",
        "year": 2017
    },
    "vPIPLuV9": {
        "id": "vPIPLuV9",
        "title": "Water-soluble artemisinin derivatives as promising therapeutic immunosuppressants of autoimmune diseases",
        "abstract": "Artemisinin, which contains a sesquiterpene trioxane skeleton, was originally isolated from Artemisia annua L., a traditional Chinese medicine with antimalarial activity.",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Jianping Zuo",
                "org": ""
            },
            {
                "name": "Wei Tang",
                "org": ""
            }
        ],
        "venue": "Cellular & Molecular Immunology",
        "year": 2017
    },
    "IfLOIMFH": {
        "id": "IfLOIMFH",
        "title": "Artemisinin analogue SM934 ameliorates DSS-induced mouse ulcerative colitis via suppressing neutrophils and macrophages.",
        "abstract": "Ulcerative colitis (UC) is a chronic, nonspecific inflammatory bowel disease (IBD) characterized by complicated and relapsing inflammation in the gastrointestinal tract. SM934 is a water-soluble artemisinin analogue that shows anti-inflammatory and immuno-regulatory effects. In this study, we investigated the effects of SM934 on UC both in vivo and in vitro. A mouse model of colitis was established in mice by oral administration of 5% dextran sulfate sodium (DSS). SM934 (3, 10 mg/kg per day, ig) was administered to the mice for 10 days. After the mice were sacrificed, colons, spleens and mesenteric lymph nodes (MLNs) were collected for analyses. We showed that SM934 administration restored DSS-induced body weight loss, colon shortening, injury and inflammation scores. Furthermore, SM934 administration significantly decreased the disease activity index (DAI), histopathological scores, and myeloperoxidase (MPO) activities in colonic tissues. Moreover, SM934 administration dose-dependently decreased the mRNA and protein levels of DSS-induced pro-inflammatory cytokines (IL-1\u03b2, IL-6 and TNF-\u03b1), and the percentage of macrophages and neutrophils in colon tissues. The effects of SM934 on LPS-stimulated RAW 264.7 cells and THP-1-derived macrophages were examined in vitro. Treatment with SM934 (0.8, 8, 80 \u03bcmol/L) dose-dependently decreased the production of pro-inflammatory mediators in LPS-stimulated RAW264.7 cells and THP-1-derived macrophages via inhibiting activation of the NF-\u03baB signaling. Our results reveal the protective effects of SM934 on DSS-induced colitis can be attributed to its suppressing effects on neutrophils and macrophages and its inhibitory role in the NF-\u03baB signaling, suggests that SM934 might be a potential effective drug for ulcerative colitis.",
        "keywords": "",
        "authors": [
            {
                "name": "Yu-Xi Yan",
                "org": "University of Chinese Academy of Sciences, Beijing 100049, China."
            },
            {
                "name": "Mei-Juan Shao",
                "org": "Laboratory of Immunology and Virology, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China."
            },
            {
                "name": "Qing Qi",
                "org": "Laboratory of Immunopharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China."
            },
            {
                "name": "Yan-Sheng Xu",
                "org": "Laboratory of Immunology and Virology, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China."
            },
            {
                "name": "Xiao-Qian Yang",
                "org": "Laboratory of Immunopharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China."
            },
            {
                "name": "Feng-Hua Zhu",
                "org": "Laboratory of Immunopharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China."
            },
            {
                "name": "Shi-Jun He",
                "org": "Laboratory of Immunopharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China."
            },
            {
                "name": "Pei-Lan He",
                "org": "Laboratory of Immunopharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China."
            },
            {
                "name": "Chun-Lan Feng",
                "org": "Laboratory of Immunopharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China."
            },
            {
                "name": "Yan-Wei Wu",
                "org": "Laboratory of Immunopharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China."
            },
            {
                "name": "Heng Li",
                "org": "University of Chinese Academy of Sciences, Beijing 100049, China."
            },
            {
                "name": "Wei Tang",
                "org": "University of Chinese Academy of Sciences, Beijing 100049, China."
            },
            {
                "name": "Jian-Ping Zuo",
                "org": "Laboratory of Immunology and Virology, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China."
            }
        ],
        "venue": "Acta pharmacologica Sinica",
        "year": 2018
    },
    "14l9qQUz": {
        "id": "14l9qQUz",
        "title": "Anti-inflammatory constituents from Perilla frutescens on lipopolysaccharide-stimulated RAW264.7 cells.",
        "abstract": "Perilla frutescens (L.) Britt. (Lamiaceae) is a traditionally medicinal herb in East Asian countries to treat various diseases. In present study, the low-polarity constituents of the aerial parts of P. frutescens were investigated and their anti-inflammatory effect on lipopolysaccharide (LPS)-stimulated RAW264.7 cells were assayed. Three new furanoid monoterpenoids, named as frutescenones A - C (1-3), together with thirteen known compounds (4-16) were isolated and identified on the basis of extensive spectroscopic analysis and a single-crystal X-ray diffraction study. Among these components, 1 is an unusual monoterpenoid with 2,3'-bifuran skeleton, and 3 is a rare perillaketone-adenine hybrid heterodimer, while the revised NMR arrangements of 4 were reported at the first time. Furthermore, monoterpenoid 4 and alkaloid 15 showed remarkably inhibitory effect on the production of inflammatory mediator (NO) and pro-inflammatory cytokines (TNF-\u03b1 and/or IL-6) in LPS-stimulated RAW264.7 cells.",
        "keywords": [
            "Anti-inflammation",
            "Lamiaceae",
            "Monoterpenoid",
            "Perilla frutescens",
            "RAW264.7 cell"
        ],
        "authors": [
            {
                "name": "Xiao-Feng Wang",
                "org": "Department of Natural medicinal Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; School of Pharmacy, University of Chinese Academy of Sciences, Beijing 100049, China."
            },
            {
                "name": "Heng Li",
                "org": "Laboratory of Antiinflammation & Immunopharmacology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; School of Pharmacy, University of Chinese Academy of Sciences, Beijing 100049, China."
            },
            {
                "name": "Kun Jiang",
                "org": "Department of Natural medicinal Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China."
            },
            {
                "name": "Qi-Qi Wang",
                "org": "Department of Natural medicinal Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; School of Pharmacy, University of Chinese Academy of Sciences, Beijing 100049, China."
            },
            {
                "name": "Yan-Hai Zheng",
                "org": "R & D Center of Plant Factory, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China."
            },
            {
                "name": "Wei Tang",
                "org": "Laboratory of Antiinflammation & Immunopharmacology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China. Electronic address: tangwei@simm.ac.cn."
            },
            {
                "name": "Chang-Heng Tan",
                "org": "Department of Natural medicinal Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China. Electronic address: chtan@simm.ac.cn."
            }
        ],
        "venue": "Fitoterapia",
        "year": 2018
    },
    "QqQNHt3b": {
        "id": "QqQNHt3b",
        "title": "Further new eunicellin-based diterpenoids from the Guangxi Weizhou soft coral Cladiella krempfi.",
        "abstract": "Three new polyoxygenated diterpenes (1, 3 and 4) of eunicellin-type, namely, 8-n-butyryl-litophynol A, 6-keto-litophynol B and 6-epi-litophynol B, respectively, together with two related known ones (2 and 5), were isolated from the soft coral Cladiella krempfi collected off the Weizhou island, Guangxi Zhuang Autonomous Region, China. The structures of the new compounds were elucidated by extensive spectroscopic analysis and chemical correlation. In bioassay, all the new compounds displayed moderate anti-inflammatory effects.",
        "keywords": "",
        "authors": [
            {
                "name": "Tong Ru",
                "org": "State Key Laboratory of Drug Research, Shanghai, Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China."
            },
            {
                "name": "You-Sheng Cai",
                "org": "Institute of TCM and Natural Products, School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, China."
            },
            {
                "name": "Heng Li",
                "org": "State Key Laboratory of Drug Research, Shanghai, Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China."
            },
            {
                "name": "Wei Tang",
                "org": "State Key Laboratory of Drug Research, Shanghai, Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China."
            },
            {
                "name": "Hong Wang",
                "org": "College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014, China."
            },
            {
                "name": "Yue-Wei Guo",
                "org": "State Key Laboratory of Drug Research, Shanghai, Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014, China. Electronic address: ywguo@simm.ac.cn."
            }
        ],
        "venue": "Fitoterapia",
        "year": 2018
    },
    "gfWI2huG": {
        "id": "gfWI2huG",
        "title": "Design and Synthesis of Marine Phidianidine Derivatives as Potential Immunosuppressive Agents.",
        "abstract": "A series of novel marine phidianidine derivatives were designed, synthesized, and evaluated for their immunosuppressive activities during our search of potential immunosuppressive agents with high efficacy and low toxicity from marine sources. These compounds were tested for their inhibitory activity on Con A-induced T cells and LPS-induced B cells proliferation. Compounds 14a and 18c, displaying the most promising inhibitory effects and low toxicities, were further found to possess immune-regulatory activities upon cross-linking of T cell receptor (TCR) and B cell receptor (BCR) on purified T and B cells, respectively.",
        "keywords": "",
        "authors": [
            {
                "name": "Jin Liu",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Kaixian Chen",
                "org": ""
            },
            {
                "name": "Jianping Zuo",
                "org": ""
            },
            {
                "name": "Yue-Wei Guo",
                "org": ""
            },
            {
                "name": "Wei Tang",
                "org": ""
            },
            {
                "name": "Xu-Wen Li",
                "org": ""
            }
        ],
        "venue": "Journal of medicinal chemistry",
        "year": 2018
    },
    "WAbanipy": {
        "id": "WAbanipy",
        "title": "Bioactive polyoxygenated cembranoids from a novel Hainan chemotype of the soft coral Sinularia flexibilis.",
        "abstract": "Different chemotypes of Sinularia flexibilis exist in the Hainan island. Thus, a collection of this soft coral from a location different from the one of our previous study afforded three novel cembranoid esters featuring a n-butyl alcohol moiety, a structural element rare in natural products of both terrestrial and marine origin. The structures of the new compounds were elucidated by detailed spectroscopic analysis and by the comparison of their spectroscopic data with those reported in the literature. In addition, the absolute stereochemistry of the previously reported diepoxycembrene (9) was first time determined by the X-ray diffraction analysis. In bioassays, compounds 6-8 exhibited strong anti-inflammatory effect with IC values of 2.7, 4.7, and 4.2\u202f\u03bcM, respectively, whereas compound 5 displayed cytotoxicity against several cancer cells with IC values ranging from 8.9 to 27.4\u202f\u03bcM. A preliminary structural-activity relationship (SAR) was also described.",
        "keywords": [
            "Absolute configuration",
            "Anti-inflammatory effect",
            "Cembrane",
            "Sinularia flexibilis",
            "South China Sea"
        ],
        "authors": [
            {
                "name": "Qihao Wu",
                "org": "State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Zhangjiang Hi-Tech Park, Shanghai 201203, China; College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014, China."
            },
            {
                "name": "Xu-Wen Li",
                "org": "State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Zhangjiang Hi-Tech Park, Shanghai 201203, China."
            },
            {
                "name": "Heng Li",
                "org": "State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Zhangjiang Hi-Tech Park, Shanghai 201203, China."
            },
            {
                "name": "Li-Gong Yao",
                "org": "State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Zhangjiang Hi-Tech Park, Shanghai 201203, China."
            },
            {
                "name": "Wei Tang",
                "org": "State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Zhangjiang Hi-Tech Park, Shanghai 201203, China."
            },
            {
                "name": "Ze-Hong Miao",
                "org": "State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Zhangjiang Hi-Tech Park, Shanghai 201203, China."
            },
            {
                "name": "Hong Wang",
                "org": "College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014, China. Electronic address: hongw@zjut.edu.cn."
            },
            {
                "name": "Yue-Wei Guo",
                "org": "State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Zhangjiang Hi-Tech Park, Shanghai 201203, China; College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014, China. Electronic address: ywguo@simm.ac.cn."
            }
        ],
        "venue": "Bioorganic & medicinal chemistry letters",
        "year": 2018
    },
    "j2pGGP2S": {
        "id": "j2pGGP2S",
        "title": "(5R)-5-Hydroxytriptolide ameliorates lupus nephritis in MRL/lpr mice by preventing infiltration of immune cells.",
        "abstract": "(5R)-5-Hydroxytriptolide (LLDT-8), a triptolide derivative with low toxicity, was previously reported to have strong immunosuppressive effects both in vitro and in vivo, but it remains unknown whether LLDT-8 has a therapy effect on systemic lupus erythematosus. In this study, we aimed to investigate the therapeutic effects of LLDT-8 on lupus nephritis in MRL/lpr mice, a model of systemic lupus erythematosus. Compared with vehicle group, different clinical parameters were improved upon LLDT-8 treatment: prolonged life-span of mice, decreased proteinuria, downregulated blood urea nitrogen and serum creatinine, reduced glomerular IgG deposits, and ameliorated histopathology. A decreased expression of the inflammatory cytokines IFN-\u03b3, IL-17, IL-6, TNF-\u03b1 was also observed in the kidney of LLDT-8 treated MRL/lpr mice. Moreover, infiltration of T cells into kidney was mitigated after LLDT-8 treatment, which was corresponding with decreased expression of related chemokines IP-10, Mig, and RANTES in kidney. The proportion of macrophage and neutrophil cells and related chemokines expression were also reduced in kidney of LLDT-8 treated mice. In human proximal tubule epithelial cell line and mouse mesangial cell line, consistent with our in vivo experiment results, LLDT-8 suppressed the expression of related chemokines and IL-6. In summary, LLDT-8 has a therapeutic benefit for lupus nephritis via suppressing chemokines expression and inhibiting immune cells infiltration in kidneys of MRL/lpr mice.",
        "keywords": "",
        "authors": [
            {
                "name": "Luyao Zhang",
                "org": "Shanghai Institute of Materia Medica, Chinese Academy of Sciences and University of Chinese Academy of Sciences, Beijing, China"
            },
            {
                "name": "Heng Li",
                "org": "Shanghai Institute of Materia Medica, Chinese Academy of Sciences and University of Chinese Academy of Sciences, Beijing, China"
            },
            {
                "name": "Yan-wei Wu",
                "org": "Shanghai Institute of Materia Medica, Chinese Academy of Sciences and University of Chinese Academy of Sciences, Beijing, China"
            },
            {
                "name": "Lei Cheng",
                "org": "Shanghai Institute of Materia Medica, Chinese Academy of Sciences and University of Chinese Academy of Sciences, Beijing, China"
            },
            {
                "name": "Yu-xi Yan",
                "org": "Shanghai Institute of Materia Medica, Chinese Academy of Sciences and University of Chinese Academy of Sciences, Beijing, China"
            },
            {
                "name": "Xiao-qian Yang",
                "org": "Shanghai Institute of Materia Medica, Chinese Academy of Sciences"
            },
            {
                "name": "Feng-Hua Zhu",
                "org": "Shanghai Institute of Materia Medica, Chinese Academy of Sciences"
            },
            {
                "name": "Shi-jun He",
                "org": "Shanghai Institute of Materia Medica, Chinese Academy of Sciences"
            },
            {
                "name": "Wei Tang",
                "org": "Shanghai Institute of Materia Medica, Chinese Academy of Sciences"
            },
            {
                "name": "Jianping Zuo",
                "org": "Shanghai Institute of Materia Medica, Chinese Academy of Sciences"
            }
        ],
        "venue": "American Journal of Physiology-renal Physiology",
        "year": 2017
    },
    "PcNv2Ndl": {
        "id": "PcNv2Ndl",
        "title": "Discovery of new BTK inhibitors with B cell suppression activity bearing a 4,6-substituted thieno[3,2-d]pyrimidine scaffold",
        "abstract": "A series of 4,6-substituted thieno[3,2-d]pyrimidine derivatives as Brutonu0027s tyrosine kinase (BTK) inhibitors are designed, synthesized and evaluated for their enzymatic inhibition and immunosuppressive activities. These derivatives exhibit varying inhibitory activities against BTK in vitro. Compound 8 is a novel potent BTK inhibitor which has an IC50 value of 29.9 nM, exerts excellent immunosuppressive activity by inhibiting the proliferation of B cells (IC50 = 284 nM), and shows low cytotoxicity (CC50 = 53\u2006632 nM) on murine splenocytes. In addition, compound 8 displays considerable selectivity between T cells (IC50 u003e 10 \u03bcM) and B cells. Furthermore, enzymatic assays on more than twenty kinases confirm that compound 8 is more selective than the reference compound Olmutinib. In summary, the results suggest that compound 8 is a potential BTK inhibitor for further evaluation and modification of the C-4 and C-6 position of the thieno[3,2-d]pyrimidine scaffold, which could be considered a new strategy in the development of BTK inhibitors.",
        "keywords": "",
        "authors": [
            {
                "name": "Qiumeng Zhang",
                "org": "School of Chemistry and Molecular Engineering, East China Normal University, 3663 North Zhongshan Road,Shanghai 200062,P. R. China"
            },
            {
                "name": "Luyao Zhang",
                "org": "Laboratory of Immunopharmacology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences,Shanghai 201203,P. R. China"
            },
            {
                "name": "Jie Yu",
                "org": "School of Chemistry and Molecular Engineering, East China Normal University, 3663 North Zhongshan Road,Shanghai 200062,P. R. China"
            },
            {
                "name": "Heng Li",
                "org": "Laboratory of Immunopharmacology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences,Shanghai 201203,P. R. China"
            },
            {
                "name": "Shi-jun He",
                "org": "Laboratory of Immunopharmacology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences,Shanghai 201203,P. R. China"
            },
            {
                "name": "Wei Tang",
                "org": "Laboratory of Immunopharmacology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences,Shanghai 201203,P. R. China"
            },
            {
                "name": "Jianping Zuo",
                "org": "Laboratory of Immunopharmacology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences,Shanghai 201203,P. R. China"
            },
            {
                "name": "Wei Lu",
                "org": "School of Chemistry and Molecular Engineering, East China Normal University, 3663 North Zhongshan Road,Shanghai 200062,P. R. China"
            }
        ],
        "venue": "RSC Advances",
        "year": 2017
    },
    "t1CJVIK5": {
        "id": "t1CJVIK5",
        "title": "Phosphodiesterase-4 Inhibitors for the Treatment of Inflammatory Diseases",
        "abstract": "Phosphodiesterase-4 (PDE4), mainly distributing in immune cells, epithelial cells and brain cells, manifests as an intracellular non-receptor enzyme modulating inflammation and epithelial integrity. Inhibition of PDE4 is predicted to have broad biological effects via elevating the level of cyclic adenosine monophosphate (cAMP) and related pathways and subsequently regulating a wide array of genes and proteins. PDE4 has been identified to be a therapeutic target for treating diverse pulmonary, dermatological and severe neurological diseases. Over the past decades, numerous PDE4 inhibitors have been designed and synthesized, among which roflumilast, apremilast and crisaborole were approved in treating inflammatory airway diseases, psoriasis arthritis and AD, respectively. It\u2019s regrettable that the dramatic efficacies are often accompanied by nausea, emesis or gastrointestinal reactions in the further clinical application. Better yet, substantial advances have been obtained to mitigate the adverse effects and obtain better benefit-to-risk ratio. This review highlights the dialectical role of PDE4 in drug discovery and disquisitive details of certain PDE4 inhibitors to provide an overview of topics that still need to be addressed in the future.",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": "Laboratory of Anti-inflammation, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, China"
            },
            {
                "name": "Jianping Zuo",
                "org": "School of Pharmacy, University of Chinese Academy of Sciences, China"
            },
            {
                "name": "Wei Tang",
                "org": "Laboratory of Anti-inflammation, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, China"
            }
        ],
        "venue": "Frontiers in Pharmacology",
        "year": 2018
    },
    "oim5ZjhO": {
        "id": "oim5ZjhO",
        "title": "Phosphodiesterase-4 inhibition attenuates murine ulcerative colitis via interfering with mucosal immunity.",
        "abstract": "PDE4 inhibition by apremilast exerted protective effects in UC via interfering with mucosal immunity, which represented a promising strategy for regulating intestinal inflammation.",
        "keywords": [
            "PDE4",
            "apremilast",
            "epithelial integrity",
            "mucosal immunity",
            "ulcerative colitis"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": "School of Pharmacy, University of Chinese Academy of Sciences, Beijing, 100049, China."
            },
            {
                "name": "Chen Fan",
                "org": "Laboratory of Anti-inflammation, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China."
            },
            {
                "name": "Chunlan Feng",
                "org": "Laboratory of Anti-inflammation, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China."
            },
            {
                "name": "Yanwei Wu",
                "org": "Laboratory of Anti-inflammation, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China."
            },
            {
                "name": "Huimin Lu",
                "org": "School of Pharmacy, University of Chinese Academy of Sciences, Beijing, 100049, China."
            },
            {
                "name": "Peilan He",
                "org": "Laboratory of Immunopharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China."
            },
            {
                "name": "Xiaoqian Yang",
                "org": "Laboratory of Immunopharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China."
            },
            {
                "name": "Fenghua Zhu",
                "org": "Laboratory of Immunopharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China."
            },
            {
                "name": "Qing Qi",
                "org": "Laboratory of Anti-inflammation, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China."
            },
            {
                "name": "Yuanzhuo Gao",
                "org": "School of Pharmacy, University of Chinese Academy of Sciences, Beijing, 100049, China."
            },
            {
                "name": "Jianping Zuo",
                "org": "Laboratory of Immunopharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China."
            },
            {
                "name": "Wei Tang",
                "org": "School of Pharmacy, University of Chinese Academy of Sciences, Beijing, 100049, China."
            }
        ],
        "venue": "British journal of pharmacology",
        "year": 2019
    },
    "6wTZDicZ": {
        "id": "6wTZDicZ",
        "title": "The prognostic significance of 13q deletions of different sizes in patients with B-cell chronic lymphoproliferative disorders: a retrospective study.",
        "abstract": "Patients with chronic lymphocytic leukemia (CLL) with 13q deletion as the sole cytogenetic abnormality usually have a favorable outcome, but the frequency of the 13q14 deletion and its impact on the outcome of other B-cell chronic lymphoproliferative disorders (BCLPDs) remain unclear. To further characterize this aberration, we investigated the prognostic significance of 13q deletion in 541 patients with BCLPDs. We performed fluorescence in situ hybridization (FISH) studies with 13q locus-specific LSI-D13S25 and LSI-RB1 probes. 52.1% of the patients with CLL harbored 13q deletion, which was significantly higher than that of other BCLPDs (p\u00a0<\u00a00.001). The size of 13q deletion was heterogeneous in both CLL and other BCLPDs. However, the distribution of cases with different deletion sizes showed no significant difference between the two groups. Whereas 13q deletion was a favorable prognostic factor in CLL, a large deletion of 13q was associated with poor prognosis in terms of time to first therapy (p\u00a0=\u00a00.020), progression-free survival (p\u00a0=\u00a00.05) and overall survival (p\u00a0=\u00a00.002) in BCLPD cases other than CLL. In conclusion, the deletion of 13q varied in size both in CLL and in other BCLPDs and adversely influenced the prognosis of patients with other BCLPDs.",
        "keywords": [
            "13q14 deletion",
            "BCLPDs",
            "Interphase fish",
            "Prognosis"
        ],
        "authors": [
            {
                "name": "Shuhua Yi",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 288, Nanjing Road, Heping District, Tianjin, 300020, China."
            },
            {
                "name": "Heng Li",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 288, Nanjing Road, Heping District, Tianjin, 300020, China."
            },
            {
                "name": "Zengjun Li",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 288, Nanjing Road, Heping District, Tianjin, 300020, China. zengjunli@163.com."
            },
            {
                "name": "Wenjie Xiong",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 288, Nanjing Road, Heping District, Tianjin, 300020, China."
            },
            {
                "name": "Huimin Liu",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 288, Nanjing Road, Heping District, Tianjin, 300020, China."
            },
            {
                "name": "Wei Liu",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 288, Nanjing Road, Heping District, Tianjin, 300020, China."
            },
            {
                "name": "Rui Lv",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 288, Nanjing Road, Heping District, Tianjin, 300020, China."
            },
            {
                "name": "Zhen Yu",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 288, Nanjing Road, Heping District, Tianjin, 300020, China."
            },
            {
                "name": "Dehui Zou",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 288, Nanjing Road, Heping District, Tianjin, 300020, China."
            },
            {
                "name": "Yan Xu",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 288, Nanjing Road, Heping District, Tianjin, 300020, China."
            },
            {
                "name": "Gang An",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 288, Nanjing Road, Heping District, Tianjin, 300020, China."
            },
            {
                "name": "Lugui Qiu",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 288, Nanjing Road, Heping District, Tianjin, 300020, China. qiulg@ihcams.ac.cn."
            }
        ],
        "venue": "International journal of hematology",
        "year": 2017
    },
    "8PplUvIa": {
        "id": "8PplUvIa",
        "title": "Del17p does not always significantly influence the survival of B-cell chronic lymphoproliferative disorders.",
        "abstract": "B-cell chronic lymphoproliferative disorders (B-CLPD) comprise several entities with indolent clinical manifestations but heterogeneous survival. Cytogenetic aberrations are now the standard prognostic predictors in chronic lymphocytic leukemia (CLL) but have been less investigated in other subtypes of B-CLPD. In this study, we detected cytogenetic aberrations by fluorescence  hybridization (FISH) in 875 B-CLPD patients, based on a panel probes locating at 13q14, 11q22, 17p13 and CEP12. We identified del17p acted as the independent adverse cytogenetic predictor for overall survival (OS) in CLL. Del13q, del11q and del17p were adverse factors for OS in Waldenstr\u00f6m's macroglobulinemia in the univariate analysis but lost their role in the multivariate analysis. Trisomy 12 acted as an independent poor factor for both marginal zone lymphoma (MZL) and unclassified B-CLPD (BCLPD-U) subtype. Del17p did not impact survival in MZL and BCLPD-U patients. These contrasting results indicate different roles of the same cytogenetic aberrations in the pathogenesis of each B-CLPD subtype. As del17p contributed to the poorest survival in CLL and desired extraordinary treatment strategy, the imitation of CLL strategy to other B-CLPD with del17p should be carefully advocated based on this study.",
        "keywords": [
            "B-cell chronic lymphoproliferative disorders",
            "chronic lymphocytic leukemia",
            "cytogenetic aberration",
            "del 17p",
            "prognosis"
        ],
        "authors": [
            {
                "name": "Shuhua Yi",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, P.R.China."
            },
            {
                "name": "Zengjun Li",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, P.R.China."
            },
            {
                "name": "Dehui Zou",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, P.R.China."
            },
            {
                "name": "Wenjie Xiong",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, P.R.China."
            },
            {
                "name": "Heng Li",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, P.R.China."
            },
            {
                "name": "Rui Cui",
                "org": "Department of Hematology, Tianjin First Center Hospital, Tianjin, P.R.China."
            },
            {
                "name": "Chengwen Li",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, P.R.China."
            },
            {
                "name": "Yuting Yan",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, P.R.China."
            },
            {
                "name": "Wei Liu",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, P.R.China."
            },
            {
                "name": "Rui Lv",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, P.R.China."
            },
            {
                "name": "Zhen Yu",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, P.R.China."
            },
            {
                "name": "Weiwei Chen",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, P.R.China."
            },
            {
                "name": "Yan Xu",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, P.R.China."
            },
            {
                "name": "Gang An",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, P.R.China."
            },
            {
                "name": "Huijun Wang",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, P.R.China."
            },
            {
                "name": "Kun Ru",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, P.R.China."
            },
            {
                "name": "Tao Cheng",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, P.R.China."
            },
            {
                "name": "Jianxiang Wang",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, P.R.China."
            },
            {
                "name": "Lugui Qiu",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, P.R.China."
            }
        ],
        "venue": "Oncotarget",
        "year": 2018
    },
    "vLIXZk5Z": {
        "id": "vLIXZk5Z",
        "title": "[Rituximab combined with second line regimens for treatment of seven relapsed and refractory Hodgkin lymphoma patients].",
        "abstract": "These results indicate that the Rituximab combined with second line regimen is an effective therapy for relapsed and refractory Hodgkin lymphoma.",
        "keywords": "",
        "authors": [
            {
                "name": "Huimin Liu",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, CAMS & PUMC, Tianjin 300020, China."
            },
            {
                "name": "Heng Li",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, CAMS & PUMC, Tianjin 300020, China."
            },
            {
                "name": "Wenjie Xiong",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, CAMS & PUMC, Tianjin 300020, China."
            },
            {
                "name": "Shuhua Yi",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, CAMS & PUMC, Tianjin 300020, China."
            },
            {
                "name": "Dehui Zou",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, CAMS & PUMC, Tianjin 300020, China."
            },
            {
                "name": "Lugui Qiu",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, CAMS & PUMC, Tianjin 300020, China."
            }
        ],
        "venue": "Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi",
        "year": 2015
    },
    "2WVDlSae": {
        "id": "2WVDlSae",
        "title": "Analysis of Clinical Characteristics for 24 Cases of Nodal Marginal Zone Lymphoma.",
        "abstract": "Objective To summarize and investigate the characteristics of nodal marginal zone lymphoma (NMZL). <strong>Method</strong> The clinical data and laboratory characteristics of of NMZL patients admitted in our hospital between January 2002 and September 2013 were analyzed retrospectively. <strong>Results</strong> Twenty-four patients were enrolled in the study. The median age was 54.4 (28-70) years,and the male/female ratio was 1:1. Most of the patients (95%) had bone marrow involvement,40.9% (9/22) had elevated lactate dehydrogenase level,8.3% (2/24) had the positive expression of hepatitis C virus antibody,33.3% (6/18) had positive autoimmune antibodies,and 33.3% (8/24) had monoclonal immunoglobulins in the serum. All of the patients expressed CD19 and CD20 cell markers,whereas none of them expressed CD10 cell marker. The positive rate of CD5 marker was 10% (1/10),the positive rate of CD23 marker was 50% (5/10),whereas no patient had the expressions of both CD5 and CD23 at the same time. The total overall remission rate was 81.25%,and the total complete remission rate was 56.2%. The separate overall remission and complete remission rate had increasing trends in rituximab subgroup than subgroups without using rituximab(P=0.136,P=0.262).<strong>Conclusion</strong> NMZL has a low incidence and can be seen in both males and females. It often invades bone marrow. Rituximab may increase the response rate and even improve the progression free survival.",
        "keywords": "",
        "authors": [
            {
                "name": "Rui L\u00fc",
                "org": "Department of Lymphoma,Institute of Hematology and Blood Disease Hospital,CAMS and PUMC,Tianjin 300020,China."
            },
            {
                "name": "Shuhua Yi",
                "org": "Department of Lymphoma,Institute of Hematology and Blood Disease Hospital,CAMS and PUMC,Tianjin 300020,China."
            },
            {
                "name": "Zengjun Li",
                "org": "Department of Lymphoma,Institute of Hematology and Blood Disease Hospital,CAMS and PUMC,Tianjin 300020,China."
            },
            {
                "name": "Tingyu Wang",
                "org": "Department of Lymphoma,Institute of Hematology and Blood Disease Hospital,CAMS and PUMC,Tianjin 300020,China."
            },
            {
                "name": "Wei Liu",
                "org": "Department of Lymphoma,Institute of Hematology and Blood Disease Hospital,CAMS and PUMC,Tianjin 300020,China."
            },
            {
                "name": "Heng Li",
                "org": "Department of Lymphoma,Institute of Hematology and Blood Disease Hospital,CAMS and PUMC,Tianjin 300020,China."
            },
            {
                "name": "Wenjie Xiong",
                "org": "Department of Lymphoma,Institute of Hematology and Blood Disease Hospital,CAMS and PUMC,Tianjin 300020,China."
            },
            {
                "name": "Lugui Qiu",
                "org": "Department of Lymphoma,Institute of Hematology and Blood Disease Hospital,CAMS and PUMC,Tianjin 300020,China."
            }
        ],
        "venue": "Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae",
        "year": 2017
    },
    "vn5bOlbK": {
        "id": "vn5bOlbK",
        "title": "Serum LDH level may predict outcome of chronic lymphocytic leukemia patients with a 17p deletion: a retrospective analysis of prognostic factors in China.",
        "abstract": "These results indicated that patients with a 17p- CLL have a variable prognosis that might be predicted using simple clinical and laboratory characteristics.",
        "keywords": [
            "17p deletion",
            "chronic lymphocytic leukemia (CLL)",
            "del17p in CLL",
            "fluorescentin situ hybridization (FISH)"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300020, China."
            },
            {
                "name": "Wenjie Xiong",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300020, China."
            },
            {
                "name": "Huimin Liu",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300020, China."
            },
            {
                "name": "Shuhua Yi",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300020, China."
            },
            {
                "name": "Zhen Yu",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300020, China."
            },
            {
                "name": "Wei Liu",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300020, China."
            },
            {
                "name": "Rui Lyu",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300020, China."
            },
            {
                "name": "Tingyu Wang",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300020, China."
            },
            {
                "name": "Dehui Zou",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300020, China."
            },
            {
                "name": "Zengjun Li",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300020, China."
            },
            {
                "name": "Lugui Qiu",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300020, China."
            }
        ],
        "venue": "Chinese journal of cancer research = Chung-kuo yen cheng yen chiu",
        "year": 2017
    },
    "CuF3pgn0": {
        "id": "CuF3pgn0",
        "title": "Intratumoral Genetic Heterogeneity Provides Additional Prognostic Significance of the CLL Genomic Features",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Wenjie Xiong",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Heng Li",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Shuhua Yi",
                "org": "State Key Lab of Experimental Hematology,Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Zengjun Li",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Shizhen Zhong",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Wei Liu",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Dehui Zou",
                "org": "Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, tianjin, China"
            },
            {
                "name": "Lugui Qiu",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            }
        ],
        "venue": "Blood",
        "year": 2015
    },
    "OTzJoAEo": {
        "id": "OTzJoAEo",
        "title": "The Prognostic Significance of 13q Deletion with Different Size in Patients with B-CLPD",
        "abstract": "Background: Deletion of 13q14 is the most frequent abnormality in chronic lymphocytic leukemia (CLL). Deletion at of 13q with vary sizes have been described, documenting different involved genes with different deletion area. But the prognostic significance of different deletion size is not well explored and this interesting phenomenon has not been described in other B-cell chronic lymphoproliferative disorders (B-CLPD).Patients and Methods: Interphase fluorescence in situ hybridization (FISH) using locus-specific probes (RB1, D13S25) was performed to detect 13q14 deletions on 344 untreated cases with B-CLPD, including 304 CLL patients and 166 other B-CLPD patients. Different 13q14 deletion area was delineated by RB1 and D13S25.Results: (a) Totally, 145 of 304 CLL patients (47.9%) had 13q14 deletion, which was significantly higher than it in other B-CLPD (25/167, 15.0%; p=.000). 77 of 304 CLL patients (25.3%) and 14 of 166 other B-CLPD patients (8.4%) had RB1 deletion. RB1 deletion always accompanied with D13S25 deletion in both CLL and other B-CLPD, which indicated large area deletion in 13q14. But some patients had only D13S25 deletion without RB1 deletion, indicating small area deletion in 13q14. Of the 145 CLL cases with 13q14 deletion, 73(50.3%) had small deletion and 72 (49.7%) with large deletion. The incidence of small and large deletion in 21 other B-CLPD with 13q14 deletion were in 12(48.0%) and 113(52.0%) patients respectively.(b) In CLL cases, the time to first therapy in the cases with 13q14 deletion was 25 months longer than 16 months in the cases without 13q14 deletion (P=0.035). The progression-free survival (PFS) in cases with 13q14 deletion was also significantly longer (P=0.023) than those without the aberration. In other B-CLPD cases, the PFS and OS in cases with 13q14 deletion was significantly shorter (P=0.030) than those without the aberration. Moreover, large deletions (from RB1 to D13S25) were associated with a significantly shorter (pu003c 0.05) TFT as well as overall survival (57.5 vs. 135.0 months, p=.075)compared with small deletions.Conclusions: The deletion of 13q can influence clinical outcome of BCLPD and vary in size both in CLL and in other BCLPDs. The deletion size displayed as a poor prognostic factor in other BCLPD cases, which implies the usage of both 13q probes is proposed.Disclosures No relevant conflicts of interest to declare.",
        "keywords": "",
        "authors": [
            {
                "name": "Wenjie Xiong",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Heng Li",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Shuhua Yi",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Zengjun Li",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Wei Liu",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Rui Lv",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Dehui Zou",
                "org": "Institute of Hematology and Blood Disease Hospital,, Chinese Academy of Medical Sciences and Peking Union Medical College, tianjin, China"
            },
            {
                "name": "Lugui Qiu",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology & Blood Diseases Hospital, Tianjin, China"
            }
        ],
        "venue": "Blood",
        "year": 2015
    },
    "vBlTJ0yS": {
        "id": "vBlTJ0yS",
        "title": "Reverse prognostic role of a panel cytogenetic aberrations between chronic lymphocytic leukemia and other B-cell chronic lymphoproliferative disorders",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Shuhua Yi",
                "org": ""
            },
            {
                "name": "Zengjun Li",
                "org": ""
            },
            {
                "name": "Shizhen Zhong",
                "org": ""
            },
            {
                "name": "Wenjie Xiong",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Wei Liu",
                "org": ""
            },
            {
                "name": "Rui Lv",
                "org": ""
            },
            {
                "name": "Zhen Yu",
                "org": ""
            },
            {
                "name": "Deihui Zou",
                "org": ""
            },
            {
                "name": "Lugui Qiu",
                "org": ""
            }
        ],
        "venue": "Leukemia & Lymphoma",
        "year": 2015
    },
    "OnwXGiRR": {
        "id": "OnwXGiRR",
        "title": "The Addition of Novel Agents to Front-Line Therapy Significantly Improve the Short-Term and Long-Term Therapeutic Effects of High Risk Waldenstrom's Macroglobulinemia Patients in China",
        "abstract": "Background: Waldenstromu0027s Macroglobulinemia (WM) is a B-cell proliferative malignancy characterized by immunoglobulin M monoclonal gammopathy and bone marrow infiltrated by B cell, lymphoplasmacytic cells and plasma cells. Some studies have shown that novel agents such as Rituximab and Bortezomib combined chemotherapy could improve WM patientsu0027 survival. However, few studies had focused on the efficiency of these agents on ISSWM intermediate or high risk group and no systematical investigations had been published for the Eastern WM patients.Methods: We systematically reviewed the records of 91 WM patients with intermediate or high risk ISSWM group, who had been diagnosed at Institute of Hematology u0026 Blood Disease Hospital, Chinese Academy of Medical Sciencesu0026 Peking Union Medical College.Results: There was male predominant (75.8%) for the entire population, with a median age of 62 years (range32-87) at diagnosis. There were 36(39.6%) and 55(60.4%) patients in the intermediate or high risk ISSWM group, respectively. The percentage of hepatomegaly, splenomegaly, B symptomand elevated LDH were 16.9%, 34.1%, 33.3% and 18.6%, respectively. Among them, 36 patients received novel agents combination first-line chemotherapy and 55 patients received conventional chemotherapy. The complete remission (CR) rate and overall response rate(ORR) were 26.5% and 76.5% in the novel agent group respectively, which were higher than the conventional group( 26.5% v.s. 10%p=0.047; 76.5% v.s.56%, p=0.055). With a median follow-up of 35 months, The novel agent group induced a significantly longer progression-free survival (PFS) compared with the conventional group (77months v.s.45 months, p=0.04).The mediate overall survival (OS) in the novel agent group was not reached, which was also significantly longer than the conventional group(NR v.s. 62months,p=0.045).Conclusion: Compared with the conventional therapy, the novel agent combination significantly improved the short-term and long-term therapeutic effects in intermediate/high risk patients of WM.Disclosures No relevant conflicts of interest to declare.",
        "keywords": "",
        "authors": [
            {
                "name": "Wenjie Xiong",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Shuhua Yi",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Heng Li",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Zengjun Li",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Rui Lv",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Wei Liu",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Yan Xu",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Dehui Zou",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Mu Hao",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Lugui Qiu",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            }
        ],
        "venue": "Blood",
        "year": 2016
    },
    "a1wImO7r": {
        "id": "a1wImO7r",
        "title": "Development of a Novel Prognostic Scoring System of Time to First Treatment for Chinese Patients with Chronic Lymphocytic Leukemia",
        "abstract": "Background: The established clinical staging systems (Rai/Binet) of chromic lymphoma leukemia (CLL) had limitedly discriminated among prognostic groups, especially for the patients in early stages and without treatment indications. In the past two decades, several prognostic factors have been identified to predict the outcome of patients with CLL, but only a few studies investigated the prognostic improvement of the combination of more markers together. In order to predict the time to first treatment (TTFT) in patients of early stages, we evaluated the prognostic role of conventional bio-markers as well as cytogenetic abnormalities and combined them together in a new prognostic scoring system, the CLL prognostic index.Patients and Methods: Taking advantage of a population of 402 untreated Chinese patients with CLL at early and advanced stage of disease, we identified the strongest prognostic markers of TTFT and, subsequently, in a cohort of 173 patients who had complete data for all 3 variables, we integrated the data of traditional staging system, cytogenetic aberrations and mutational status of immunoglobulin heavy chain variable region ( IGHV ) in CLL-PI. The median follow-up time was 45 months (ms). Multivariable statistics were applied with software SPSS 17.0, and the end point was TTFT.Results: Based on multivariate Cox regression analysis, three independent factors for TTFT were identified: advanced clinical stage (Rai risk group), 17p deletion and unmutated IGHV . Applying weighted grading of these independent factors, a CLL-PI was constructed based on regression parameters, which could categorize four different risk groups [low risk (score 0), intermediate low (score 1), intermediate high (score 2) and high risk (score 3-6)] with significantly different TTFT (median TTFT of NR, 65.0 ms, 36.0 ms and 19.0 ms, respectively, pu003c0.001).Conclusions: This study developed a weighted, integrated CLL-PI prognostic system of CLL patients which combines the critical genetic prognostic markers ( IGHV mutation status, 17p deletion) with traditional clinical stage (Rai staging system). This novel modified PI system could be used to discriminate among groups and may help predict the TTFT and prognosis of patients with CLL.Disclosures No relevant conflicts of interest to declare.",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Wenjie Xiong",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Zengjun Li",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Shuhua Li",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Rui Lv",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Dehui Zou",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Lugui Qiu",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            }
        ],
        "venue": "Blood",
        "year": 2016
    },
    "kdTtGk4Q": {
        "id": "kdTtGk4Q",
        "title": "Different Prognostic Significance of a Panel Cytogenetic Aberrations Between Chronic Lymphocytic Leukemia and Other B-Cell Chronic Lymphoproliferative Disorders",
        "abstract": "Background : B-cell chronic lymphoproliferative disorders (B-CLPD) comprise several entities with similar clinical manifestations, within which chronic lymphocytic leukemia (CLL) account for the majority, others including follicular lymphoma (FL), hairy cell leukemia (HCL), splenic marginal zone lymphoma (SMZL),nodal marginal zone lymphoma (NMZL), gastric mucosa-associated lymphoid tissue (MALT) lymphoma, lymphoplasmacytic lymphoma/Waldenstromu0027s macroglobulinemia (LPL/WM), and other unclassified subtypes. Cytogenetic aberrations are now the main prognostic predicators in CLL, with deletion of TP53 or ATM as the adverse predicators, while sole deletion of 13q14 as the favorable one, trisomy 12 and IGH translocation as the neutral factors. The prognostic role of this cytogenetic aberrations panel has not been well established in other B-CLPD excluding CLL.Patients and methods : A panel of DNA probes were used to detect cytogenetic aberrations by fluorescence in situ hybridization (FISH), including RB1/D13S25 at 13q14, ATM at 11q22, TP 53 at 17p13, CEP12 and IGH translocation at 14q32. Totally, 870 patients were enrolled in this study, including 459 CLL patients, 41 SMZL patients, 24 HCL patients, 96 LPL/WM patients, 24 NMZL patients with bone marrows involvement (BMI) ,59 FL patients with BMI and 161 patients without definite subtype classification.Results : The incidence of each cytogenetic aberration in CLL is as follow: 38.0%(169/445) for del 13q14, 11.5% (46/400) for del 11q22, 14.5% (66/455) for del 17p13 , 23.8% (68/286) for +12, and 21.9% (97/443) for t(14q32). While in other B-CLPD excluding CLL is as follow: 10.3% (36/351) for del 13q14, 3.6% (11/305) for del 11q22, 7.9% (30/380) for del 17p13, 12.3% (23/ 187) for +12 and 24.1% (93/386) for t(14q32). The incidence of del 13q14 (p=.000), del 11q22 (p=.000), del17p13 (p=.003) and +12 (p=.002) were higher in CLL than in other B-CLPD. With a median follow-up of 46.0 months (2.0-288.0) in CLL and 39 months (3.0-239.0) in other B-CLPD, the median estimated progress-free survival (PFS) and overall survival (OS) in CLL were 80.0 months (95% CI 67.2-92.7) and 129 months (95% CI 111.5-146.5) respectively, while in other B-CLPD were 84 months (95% CI 71.8-96.1) and 135 months respectively.In CLL, the del 13q (p=.046), del 11q (p=.002) and del 17p (pu003c.001) were the adverse predictors for the PFS with only del 17p (pu003c.001) for the OS. There were no significant difference between patients with or without del 13q in aspect of OS (129.0 vs 110.5 months, p=.207). while sole del 13q was the favorable predictor for both PFS (pu003c.001) and OS (p=.001). Del 11q also indicated poor OS without statistical significance (p=.112). The median PFS for patients with or without +12 was 90 months (95% CI 60.5-119.5) and 93.0 months (95% CI 73.3-112.7) (p=.273), and the median OS was also similar (131.0 months vs. 129.0, p=.921). IGH translocation did not significantly influence both PFS (p=.198) and OS (p=.648).In other B-CLPD except CLL, the del 13q, del 17p and t (14q32) had no impact on both PFS (p=.983, p=.910 and p=.675 respectively) and OS (p=.171, p=.401 and p=.453 respectively). But patients with trisomy 12 had poor PFS (69.0 vs.86.0months, p=.094) and OS (69.0 vs.135.0months, p=.006) compared with those without. Del 11q also adversely impacted the OS (75.0 months vs. not reached, p=.059) but not PFS (62.0 vs. 84.0 months, p=.735).Conclusions : Del 11q and del 17p had the adverse prognostic impact in CLL. However, trisomy 12 was the predictor of poor survival in other B-CLPD which indicated neutral prognostic role in CLL. These results may imply different role of the same cytogenetic aberration in the pathology between CLL and other B-CLPD.Disclosures No relevant conflicts of interest to declare.",
        "keywords": "",
        "authors": [
            {
                "name": "Wenjie Xiong",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Shuhua Yi",
                "org": ""
            },
            {
                "name": "Zengjun Li",
                "org": ""
            },
            {
                "name": "Shizhen Zhong",
                "org": ""
            },
            {
                "name": "Wei Liu",
                "org": ""
            },
            {
                "name": "Rui Lv",
                "org": ""
            },
            {
                "name": "Dehui Zou",
                "org": ""
            },
            {
                "name": "Lugui Qiu",
                "org": ""
            }
        ],
        "venue": "Blood",
        "year": 2015
    },
    "OSP6gGSH": {
        "id": "OSP6gGSH",
        "title": "A Novel Hierarchical Prognostic Model Based on Clinical Feature and Cytogenetics for Splenic Marginal Zone Lymphoma",
        "abstract": "Background:  Splenic marginal zone lymphoma (SMZL) is a rare indolent B-cell neoplasm, which often involved with spleen, bone marrow (BM), and sometimes involved with the peripheral blood. However, the clinical characteristics of Chinese SMZL patients remain elusive.. This present study is undertaken to systematically analyze the clinical and biological characteristics of SMZL in Chinese patients, and draw out an appropriate hierarchical prognostic model of SMZL in the rituximab era.   Method:  A total of 172 patients with newly diagnosed SMZL in Institute of hematology and blood disease hospital were retrospectively analyzed. Clinical characteristics, including flow cytometry analysis of tumor cells, immunohistochemistry, cytogenetics and molecular detection data were collected and IgHV mutation status, fluorescence in situ hybridization (FISH) data were carried out on patients with available samples.   Result:  The median age at diagnosis of 172 patients with SMZL was 57 years (range 25-81) and male having little prominence (52.3%). Using a homology cut-off value of 98% to the nearest germline gene, we observed mutated IGHV in 29 (74.4%) and unmutated IGHV in 10 (25.6%) of the 39 SMZL patients. The most frequently used fragments of IGHV gene were IGHV1-2 (25.6%), IGHV4-34 (15.4%), IGHV2-27 and IGHV3-30 (10.3% and 7.8% respectively). The 49.0% patients had HBV infection currently or before SMZL diagnosis, and 14.6% with active HBV infection. Chromosomal aberration was noted in 21.2% patients and 14.4% patients have complex karyotype (more than three aberrations). The FISH detection indicated that the cytogenetic aberrant of 13q- (Rb1/ D13S25), trisomy 12, 17p-(TP53) and t(14q32) was 9.8% (8/82), 9.6% (8/83), 4.7% (6/126) and 20.4% (19/93), respectively. Among those patients, 64 patients (41.6%) received rituximab-based immunochemotherapy as the first line treatment and other 37 patients (24.0%) with conventional chemotherapy treatment alone.  With a median follow-up of 50.5 months (range, 6-214 months), the estimated 5-year failure-free survival (FFS) and overall survival (OS) rates were 74.6% and 80.8%, respectively. The 5-year FFS for patients with rituximab-based treatment was significantly prolonged than those rituximab-free treatment patients (89.9% vs 60.9%, P = 0.005). Based on the univariate analysis, the significant predictive parameters for shorter OS included hemoglobin level   Using above 3 independent variables, we identified a novel hierarchical prognostic model with three risk groups: low-risk group (39.2%) with no adverse factors, intermediate-risk group (38.6%) with one factor and high-risk group (22.1%) with 2 or 3 factors. The 5-year OS was 96.7%, 78% and 53.3%, respectively (p=0.000). The 5-year FFS was 95%, 67.5% and 39.4%, respectively (p=0.000). The novel hierarchical prognostic model showed an advanced c-index than the other risk models, including IPI, FLIPI and the tradition SMZL score significantly.   Conclusion:  Chinese patients with SMZL have distinct clinical characteristics. The novel prognostic index system composed of hemoglobin, HBVs-Ag and complex karyotype aberrant could effectively stratify the outcomes of patients with SMZL and appears to be a promising risk model for Chinese SMZL patients in the rituximab era.  Disclosures  No relevant conflicts of interest to declare.",
        "keywords": "",
        "authors": [
            {
                "name": "Yuting Yan",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Wenjie Xiong",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Shuhua Yi",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Rui Lv",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Zhen Yu",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Wei Liu",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Heng Li",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Huimin Liu",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Zengjun Li",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Dehui Zou",
                "org": "Institute of Hematology and Blood Disease Hospital,, Chinese Academy of Medical Sciences and Peking Union Medical College, tianjin, China"
            },
            {
                "name": "Mu Hao",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Lugui Qiu",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            }
        ],
        "venue": "Blood",
        "year": 2016
    },
    "qo8DYQnu": {
        "id": "qo8DYQnu",
        "title": "Prognostic Significance of Serum LDH in B Cell Chronic Lymphoproliferative Disorders: A Single-Institution Study of 829 Cases in China",
        "abstract": "Background:  B-cell chronic lymphoproliferative disorders (B-CLPD) comprise several indolent lymphoma subtypes with similar characteristics but also difference and heterogeneity. Several prognostic systems had been established for separate subtypes, such as Rai/Binet stage system for CLL, FLIPI for follicular lymphoma. Here, we want to explore the prognostic role of some common clinical characteristics in each lymphoma subtype, such as serum LDH.   Materials and methods:  The clinical data of 829 patients with B-CLPD including clinical features, LDH expression level, cytogenetic abnormalities and therapeutic outcome were analyzed retrospectively in department of lymphoma u0026 myeloma, Institute of hematology u0026 Blood disease hospital from April 1990 to August 2013, and the prognosis of B-CLPD patients with different expression levels of LDH was compared, including overall survival (OS) and progression-free survival (PFS) rates.   Results:  829 patients were divided into three groups, including 426 (51.4%) patients with chronic lymphocytic lymphoma (CLL), 307 (37.0%) patients with non-CLL B-CLPD and 96 (11.6%) patients with BLPD-U. Elevated serum LDH at diagnosis was detected in 112 (26.3%), 85 (27.7%) and 23 (24.9%) of CLL, non-CLL B-CLPD and BLPD-U group, respectively. Patients with elevated LDH B-CLPD had poorer 5-year overall survival rate (CLL: 63.8% vs 83.0%; non-CLL B-CLPD: 62.2% vs 78.1%; BLPD-U: 47.4% vs 88.6%) and 5-year progression-free survival rate (CLL: 52.0% vs 78.2%; non-CLL B-CLPD: 40.8% vs 75.6%; BLPD-U: 48.9% vs 89.5%) than LDH normal patients. Univariate analysis showed that LDH expression, hemoglobin level, platelet count, B symptoms, P53 deletion were prognostic factors for CLL patient survival, while LDH expression, platelet count, albumin level affected non-CLL B-CLPD patient survival significantly and LDH expression, albumin level, ECOG PS scores for BLPD-U patient survival. Multivariate analysis showed that elevated LDH was an independent significant prognostic factor for overall survival ( P  P    Conclusion  s:  Based on these data, we conclude that elevated serum LDH at diagnosis is an unfavorable prognostic factor in patients with B-CLPD.  Disclosures  No relevant conflicts of interest to declare.",
        "keywords": "",
        "authors": [
            {
                "name": "Huimin Liu",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Wenjie Xiong",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Heng Li",
                "org": "State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Rui Lv",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Wei Liu",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Shuhua Yi",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Zengjun Li",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Lugui Qiu",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            }
        ],
        "venue": "Blood",
        "year": 2016
    },
    "CaZSYx1G": {
        "id": "CaZSYx1G",
        "title": "The Clinical Features and Prognosis of Lymphoplasmacytic Lymphoma/ Waldenstr\u00f6m Macroglobulinemia: A Large Series Analysis from a Single Center",
        "abstract": "Background:  Lymphoplasmacytic Lymphoma/Waldenstrommacroglobulinemia (LPL/WM) is a rare B-cell proliferative malignancy characterized by immunoglobulin M monoclonal gammopathy and /or bone marrow infiltration by lymphocyte, lymphoplasmacytic and/or plasma cells. The clinical features and prognosis of WM/LPL have less been investigated in Chinese patients. Moreover, few studies had reported the prognostic value of cytogenetic aberrations in Chinese WM/LPL patients.   Methods:  We systematically reviewed the records of 233 LPL/WM patients, who had been diagnosed at institute of Hematologyu0026Blood Disease Hospital, Chinese Academy of Medical Sciences u0026 Peking Union Medical College.   Results:  The median age of 233 patients was 62 years (range 32-87) and the male to female ratio was 2.76 (171/62). The most common symptoms at diagnosis were fatigue (59.1%) and bleeding (11.2%). The patients in low, intermediate and higher risk group of the international prognostic scoring system for WM (ISSWM) occupied 14.9%, 32.6% and 52.6%, respectively. 90.4% and 16% patients showed an elevated serum \u03b22-microglobulinand LDH. The percentages of hepatomegaly, splenomegaly, peripheral lymphadenopathy, B symptom were 14.9%, 34.5%, 43% and 29.3%, respectively. The degree of splenomegaly was always mild or moderate, only 19.1% patients with giant spleen. The karyotypes abnormalities were not common in LPL/WM patients. Only 8.9% (14/157) patients had abnormal chromosome karyotypes. The most common cytogenetic aberration detected by fluorescence in situ hybridization (FISH) were deletion of 17q13 (9/120, 7.5%), trisomy 12(5/58, 8.6%). Other aberrations include 13q14 deletion in 3 of 128 patients (2.3%), 11q22 deletion in2 of 90 patients (2.2%). Univariate analysis showed that ageu003e62 years, leukocytopenia, thrombocytopenia, anemia, cytopenias \u2265 2, elevated LDH, abnormal chromosome karyotypes, P53 deletion and high risk of ISSWM were adverse risk factors for OS. But only clinical effect not reaching partial response (p=0.006), elevated LDH (p=0.049) and leukocytopenia (p=0.048) were the independent prognostic factors at multivariate analysis.   Conclusion:  Distinct characteristics exist in WM in China compared with the Western country. Elevated LDH and leukocytopenia were the independent adviser factors for OS in this series patient.  Disclosures  No relevant conflicts of interest to declare.",
        "keywords": "",
        "authors": [
            {
                "name": "Wenjie Xiong",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Shuhua Yi",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Heng Li",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Zengjun Li",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Rui Lv",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Wei Liu",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Yan Xu",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Dehui Zou",
                "org": "Institute of Hematology and Blood Disease Hospital,, Chinese Academy of Medical Sciences and Peking Union Medical College, tianjin, China"
            },
            {
                "name": "Mu Hao",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            },
            {
                "name": "Lugui Qiu",
                "org": "Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China"
            }
        ],
        "venue": "Blood",
        "year": 2016
    },
    "vbQeLjWI": {
        "id": "vbQeLjWI",
        "title": "Two-stage revisions for culture-negative infected total knee arthroplasties: A five-year outcome in comparison with one-stage and two-stage revisions for culture-positive cases.",
        "abstract": "With combined or broad spectrum antibiotics, two-stage revision showed comparable outcome when treating culture-negative infected TKA patients at five-year follow-up.",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": "Orthopedic Department Unit 4, Chinese PLA General Hospital, 28th Fuxing Road, Haidian District, Beijing, 100853, China."
            },
            {
                "name": "Ming Ni",
                "org": "Orthopedic Department Unit 4, Chinese PLA General Hospital, 28th Fuxing Road, Haidian District, Beijing, 100853, China."
            },
            {
                "name": "Xiang Li",
                "org": "Orthopedic Department Unit 4, Chinese PLA General Hospital, 28th Fuxing Road, Haidian District, Beijing, 100853, China."
            },
            {
                "name": "Qingmeng Zhang",
                "org": "Orthopedic Department Unit 4, Chinese PLA General Hospital, 28th Fuxing Road, Haidian District, Beijing, 100853, China."
            },
            {
                "name": "Xin Li",
                "org": "Orthopedic Department Unit 4, Chinese PLA General Hospital, 28th Fuxing Road, Haidian District, Beijing, 100853, China."
            },
            {
                "name": "Jiying Chen",
                "org": "Orthopedic Department Unit 4, Chinese PLA General Hospital, 28th Fuxing Road, Haidian District, Beijing, 100853, China. Electronic address: chenjiying_301@163.com."
            }
        ],
        "venue": "Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association",
        "year": 2017
    },
    "9OHNce4D": {
        "id": "9OHNce4D",
        "title": "[EFFECTIVENESS OF BILATERAL TOTAL HIP AND KNEE ARTHROPLASTY FOR SEVERE INFLAMMATORY ARTHROPATHIES].",
        "abstract": "A combination of bilateral hip and knee arthroplasty is an efficient treatment for severe lower extremities deformity, arthralgia and poor quality of life caused by inflammatory arthropathies. However, the postoperative periprosthetic infection and stiffness of knee are important complications influencing the effectiveness of operation.",
        "keywords": [
            "Ankylosing spondylitis",
            "Inflammatory arthropathy",
            "Rheumatoid arthritis",
            "Total hip arthroplasty",
            "Total knee arthroplasty"
        ],
        "authors": [
            {
                "name": "Xin Li",
                "org": "Department of Orthopedics, General Hospital of Chinese PLA, Beijing, 100853, P.R.China."
            },
            {
                "name": "Heng Li",
                "org": "Department of Orthopedics, General Hospital of Chinese PLA, Beijing, 100853, P.R.China."
            },
            {
                "name": "Ming Ni",
                "org": "Department of Orthopedics, General Hospital of Chinese PLA, Beijing, 100853, P.R.China."
            },
            {
                "name": "Xiang Li",
                "org": "Department of Orthopedics, General Hospital of Chinese PLA, Beijing, 100853, P.R.China."
            },
            {
                "name": "Xinggui Song",
                "org": "Department of Orthopedics, General Hospital of Chinese PLA, Beijing, 100853, P.R.China."
            },
            {
                "name": "Xiangpeng Kong",
                "org": "Department of Orthopedics, General Hospital of Chinese PLA, Beijing, 100853, P.R.China."
            },
            {
                "name": "Yucong Li",
                "org": "Department of Orthopedics, General Hospital of Chinese PLA, Beijing, 100853, P.R.China."
            },
            {
                "name": "Jiying Chen",
                "org": "Department of Orthopedics, General Hospital of Chinese PLA, Beijing, 100853, P.R.China."
            }
        ],
        "venue": "Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery",
        "year": 2016
    },
    "rvvW5Tbb": {
        "id": "rvvW5Tbb",
        "title": "Is the cup orientation different in bilateral total hip arthroplasty with right-handed surgeons using posterolateral approach?",
        "abstract": "This current study demonstrated that surgeon handedness is likely to be a contributing factor that affects cup inclination and anteversion in bilateral THA and that the placement of cup performed by dominant hands of surgeons is more accurate than that performed by non-dominant sides.",
        "keywords": [
            "Anteversion",
            "Inclination",
            "Safe zone",
            "Surgeon handedness",
            "Total hip arthroplasty"
        ],
        "authors": [
            {
                "name": "Xinggui Song",
                "org": "Orthopaedic Department, Tianjin Medical University General Hospital Airport Hospital, 85 Dongliu Road, Tianjin Free Trade Zone, Tianjin, People's Republic of China."
            },
            {
                "name": "Ming Ni",
                "org": "Orthopaedic Department, Chinese PLA General Hospital, 28 Fuxing Road, Haidian District, Beijing, People's Republic of China."
            },
            {
                "name": "Heng Li",
                "org": "Orthopaedic Department, Chinese PLA General Hospital, 28 Fuxing Road, Haidian District, Beijing, People's Republic of China."
            },
            {
                "name": "Xin Li",
                "org": "Orthopaedic Department, Chinese PLA General Hospital, 28 Fuxing Road, Haidian District, Beijing, People's Republic of China."
            },
            {
                "name": "Xiang Li",
                "org": "Orthopaedic Department, Chinese PLA General Hospital, 28 Fuxing Road, Haidian District, Beijing, People's Republic of China."
            },
            {
                "name": "Jun Fu",
                "org": "Orthopaedic Department, Chinese PLA General Hospital, 28 Fuxing Road, Haidian District, Beijing, People's Republic of China."
            },
            {
                "name": "Jiying Chen",
                "org": "Orthopaedic Department, Chinese PLA General Hospital, 28 Fuxing Road, Haidian District, Beijing, People's Republic of China. chenjiying_301@126.com."
            }
        ],
        "venue": "Journal of orthopaedic surgery and research",
        "year": 2018
    },
    "hGygWXXK": {
        "id": "hGygWXXK",
        "title": "[Imaging features of hip joint in patients with ankylosing spondylitis undergoing total hip arthroplasty].",
        "abstract": "Compared with patients having osteonecrosis of the femeral head, there is no significant difference in preoperative AVA and ABA, but postoperative AVA significantly increase in patients with AS. Because AS patients have mainly chimney type medullary cavity of the femur, the filling ratio of middle and distal segment is lower when tapered stems are used, and the filling ratio of anatomic stems is higher.",
        "keywords": [
            "Ankylosing spondylitis",
            "CT three-dimensional reconstruction",
            "imaging features",
            "total hip arthroplasty"
        ],
        "authors": [
            {
                "name": "Ke Li",
                "org": "Department of Orthopedics, Beijing Rehabilitation Hospital of Capital Medical University, Beijing, 100144, P.R.China."
            },
            {
                "name": "Heng Li",
                "org": "."
            },
            {
                "name": "Fenglong Sun",
                "org": "Department of Orthopedics, Beijing Rehabilitation Hospital of Capital Medical University, Beijing, 100144, P.R.China."
            },
            {
                "name": "Xiang Li",
                "org": "Department of Orthopedics, General Hospital of Chinese PLA, Beijing, 100853, P.R.China."
            },
            {
                "name": "Qingmeng Zhang",
                "org": "Department of Orthopedics, General Hospital of Chinese PLA, Beijing, 100853, P.R.China."
            },
            {
                "name": "Chi Xu",
                "org": "Department of Orthopedics, General Hospital of Chinese PLA, Beijing, 100853, P.R.China."
            },
            {
                "name": "Xinggui Song",
                "org": "Department of Orthopedics, General Hospital of Chinese PLA, Beijing, 100853, P.R.China."
            },
            {
                "name": "Jiying Chen",
                "org": "Department of Orthopedics, General Hospital of Chinese PLA, Beijing, 100853, P.R.China.chenjiying_301@163.com."
            }
        ],
        "venue": "Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery",
        "year": 2017
    },
    "9vM7EAgg": {
        "id": "9vM7EAgg",
        "title": "Comparison of Leukocyte Esterase Testing of Synovial Fluid with Synovial Histology for the Diagnosis of Periprosthetic Joint Infection.",
        "abstract": "BACKGROUND Periprosthetic joint infection (PJI) is a complication of total joint arthroplasty (TJA). The leukocyte esterase (LE) strip test and histology are diagnostic methods for PJI. The aims of this study were to determine the sensitivity and specificity of the LE strip test and to compare it with histology in the diagnosis of PJI. MATERIAL AND METHODS Between January and December 2015, 93 patients who underwent TJA with PJI were enrolled in the study. Synovial fluid samples were tested with an LE strip, and three synovial tissue samples from each patient underwent frozen section and formalin-fixed histology. Recent criteria from the Musculoskeletal Infection Society (MSIS) were used for the diagnosis of PJI. RESULTS Ninety-three patients studied included 38 cases of PJI and 55 non-infected cases. Sensitivity and specificity of the LE strip test were 92.1% (95% CI, 77.5-97.9%) and 96.4% (95% CI, 86.4-99.4%), respectively. There was no significant difference in sensitivity (p=0.249) or specificity (p=0.480) between frozen and paraffin sections for histology; the two methods were strongly correlated (\u03c6=0.892). Comparison of the LE test results with histology showed a strong correlation (\u03c6=0.758, and \u03c6=0.840). CONCLUSIONS The findings of this preliminary study have shown that the LE strip test on synovial fluid showed similar sensitivity and specificity as histology for the diagnosis of PJI, indicating that that further controlled clinical studies should be performed to investigate the role of the LE strip test for the early diagnosis of PJI.",
        "keywords": "",
        "authors": [
            {
                "name": "Rui Li",
                "org": "Department of Orthopedics, Chinese PLA General Hospital, Beijing, China (mainland)."
            },
            {
                "name": "Xiang Li",
                "org": "Department of Orthopedics, Chinese PLA General Hospital, Beijing, China (mainland)."
            },
            {
                "name": "Baozhan Yu",
                "org": "Department of Orthopedics, Chinese PLA General Hospital, Beijing, China (mainland)."
            },
            {
                "name": "Xin Li",
                "org": "Department of Orthopedics, Chinese PLA General Hospital, Beijing, China (mainland)."
            },
            {
                "name": "Xinggui Song",
                "org": "Department of Orthopedics, Chinese PLA General Hospital, Beijing, China (mainland)."
            },
            {
                "name": "Heng Li",
                "org": "Department of Orthopedics, Chinese PLA General Hospital, Beijing, China (mainland)."
            },
            {
                "name": "Chi Xu",
                "org": "Department of Orthopedics, Chinese PLA General Hospital, Beijing, China (mainland)."
            },
            {
                "name": "Jiying Chen",
                "org": "Department of Orthopedics, Chinese PLA General Hospital, Beijing, China (mainland)."
            }
        ],
        "venue": "Medical science monitor : international medical journal of experimental and clinical research",
        "year": 2017
    },
    "mrWLm6o3": {
        "id": "mrWLm6o3",
        "title": "[Clinical research of debridement with prosthesis retention for periprosthetic joint infection after arthroplasty].",
        "abstract": "Debridement with prosthesis retention plays an important role in treating PJI after THA and TKA. These patients with sinus performing and duration of infection symptoms more than 14 days have higher risk to develop infection again.",
        "keywords": [
            "Total hip arthroplasty",
            "complication",
            "debridement",
            "influence factor",
            "periprosthetic joint infection",
            "total knee arthroplasty"
        ],
        "authors": [
            {
                "name": "Xinggui Song",
                "org": "."
            },
            {
                "name": "Xin Li",
                "org": "Department of Orthopaedics, General Hospital of Chinese PLA, Beijing, 100853, P.R.China."
            },
            {
                "name": "Junlei Song",
                "org": "Department of Orthopaedics, General Hospital of Chinese PLA, Beijing, 100853, P.R.China."
            },
            {
                "name": "Chi Xu",
                "org": "Department of Orthopaedics, General Hospital of Chinese PLA, Beijing, 100853, P.R.China."
            },
            {
                "name": "Rui Li",
                "org": "Department of Orthopaedics, General Hospital of Chinese PLA, Beijing, 100853, P.R.China."
            },
            {
                "name": "Heng Li",
                "org": "Department of Orthopaedics, General Hospital of Chinese PLA, Beijing, 100853, P.R.China."
            },
            {
                "name": "Jiying Chen",
                "org": "Department of Orthopaedics, General Hospital of Chinese PLA, Beijing, 100853, P.R.China.chenjiying_301@126.com."
            }
        ],
        "venue": "Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery",
        "year": 2018
    },
    "kPhb8ekM": {
        "id": "kPhb8ekM",
        "title": "The proper timing of second-stage revision in treating periprosthetic knee infection: reliable indicators and risk factors.",
        "abstract": "The proper timing of re-implantation should be combined with disappearance of clinical symptoms and negative intraoperative FS with spacer detention time at 12 to 16\u00a0weeks.",
        "keywords": [
            "ESR",
            "Intraoperative frozen section",
            "Periprosthetic joint infection",
            "Serum CRP",
            "Total knee revision",
            "Two-stage revision"
        ],
        "authors": [
            {
                "name": "Jun Fu",
                "org": "Department of Orthopaedics, Chinese People's Liberation Army General Hospital (301 Hospital), Beijing, 100853, China."
            },
            {
                "name": "Ming Ni",
                "org": "Department of Orthopaedics, Chinese People's Liberation Army General Hospital (301 Hospital), Beijing, 100853, China."
            },
            {
                "name": "Heng Li",
                "org": "Department of Orthopaedics, Beijing Jishuitan Hospital, Beijing, China."
            },
            {
                "name": "Xiang Li",
                "org": "Department of Orthopaedics, Chinese People's Liberation Army General Hospital (301 Hospital), Beijing, 100853, China."
            },
            {
                "name": "Wei Chai",
                "org": "Department of Orthopaedics, Chinese People's Liberation Army General Hospital (301 Hospital), Beijing, 100853, China."
            },
            {
                "name": "Yonggang Zhou",
                "org": "Department of Orthopaedics, Chinese People's Liberation Army General Hospital (301 Hospital), Beijing, 100853, China."
            },
            {
                "name": "Libo Hao",
                "org": "Department of Orthopaedics, Chinese People's Liberation Army General Hospital (301 Hospital), Beijing, 100853, China."
            },
            {
                "name": "Jiying Chen",
                "org": "Department of Orthopaedics, Chinese People's Liberation Army General Hospital (301 Hospital), Beijing, 100853, China. hy76yuy@163.com."
            }
        ],
        "venue": "Journal of orthopaedic surgery and research",
        "year": 2018
    },
    "U0JTCraO": {
        "id": "U0JTCraO",
        "title": "[COMPARISON OF CEMENTLESS TOTAL HIP ARTHROPLASTY BETWEEN WITH AND WITHOUT SUBTROCHANTERIC FEMORAL SHORTENING OSTEOTOMY IN Crowe TYPE IV DEVELOPMENTAL DYSPLASIA OF HIP].",
        "abstract": "THA can improve joint function and increase limb length in the treatment of Crowe type IV DDH. Subtrochanteric shortening osteotomy is an effective treatment which can be performed according to preoperative template measurement, leg length shortening, and the soft tissue tension.",
        "keywords": "",
        "authors": [
            {
                "name": "Zhendong Zhang",
                "org": ""
            },
            {
                "name": "Wei Chai",
                "org": ""
            },
            {
                "name": "Junlei Song",
                "org": ""
            },
            {
                "name": "Fan Yang",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Qingmeng Zhang",
                "org": ""
            },
            {
                "name": "Chi Xu",
                "org": ""
            },
            {
                "name": "Jiying Chen",
                "org": ""
            }
        ],
        "venue": "Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery",
        "year": 2015
    },
    "qklLkP61": {
        "id": "qklLkP61",
        "title": "[DISTRIBUTION AND DRUG SENSITIVITY OF PATHOGENS IN PATIENTS WITH PROSTHETIC JOINT INFECTION AFTER PRIMARY TOTAL KNEE ARTHROPLASTY].",
        "abstract": "Gram-positive cocci is the main pathogen in patients with PJI after primary TKA, which is highly resistant to penicillin and macrolides. Antibiotic treatment of this complication should be based on the result of drug sensitivity test, vancomycin and linezolid may be used before the result of drug sensitivity test. It is important to pay attention to rare and multiple resistant bacteria.",
        "keywords": "",
        "authors": [
            {
                "name": "Yunjian Yang",
                "org": ""
            },
            {
                "name": "Fan Yang",
                "org": ""
            },
            {
                "name": "Zhendong Zhang",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Jiying Chen",
                "org": ""
            }
        ],
        "venue": "Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery",
        "year": 2014
    },
    "4FINtSbO": {
        "id": "4FINtSbO",
        "title": "Is the cup orientation different in bilateral total hip arthroplasty with right-handed surgeons using posterolateral approach?",
        "abstract": "This current study demonstrated that surgeon handedness is likely to be a contributing factor that affects cup inclination and anteversion in bilateral THA and that the placement of cup performed by dominant hands of surgeons is more accurate than that performed by non-dominant sides.",
        "keywords": [
            "Anteversion",
            "Inclination",
            "Safe zone",
            "Surgeon handedness",
            "Total hip arthroplasty"
        ],
        "authors": [
            {
                "name": "Xinggui Song",
                "org": "Orthopaedic Department, Tianjin Medical University General Hospital Airport Hospital, 85 Dongliu Road, Tianjin Free Trade Zone, Tianjin, People's Republic of China."
            },
            {
                "name": "Ming Ni",
                "org": "Orthopaedic Department, Chinese PLA General Hospital, 28 Fuxing Road, Haidian District, Beijing, People's Republic of China."
            },
            {
                "name": "Heng Li",
                "org": "Orthopaedic Department, Chinese PLA General Hospital, 28 Fuxing Road, Haidian District, Beijing, People's Republic of China."
            },
            {
                "name": "Xin Li",
                "org": "Orthopaedic Department, Chinese PLA General Hospital, 28 Fuxing Road, Haidian District, Beijing, People's Republic of China."
            },
            {
                "name": "Xiang Li",
                "org": "Orthopaedic Department, Chinese PLA General Hospital, 28 Fuxing Road, Haidian District, Beijing, People's Republic of China."
            },
            {
                "name": "Jun Fu",
                "org": "Orthopaedic Department, Chinese PLA General Hospital, 28 Fuxing Road, Haidian District, Beijing, People's Republic of China."
            },
            {
                "name": "Jiying Chen",
                "org": "Orthopaedic Department, Chinese PLA General Hospital, 28 Fuxing Road, Haidian District, Beijing, People's Republic of China. chenjiying_301@126.com."
            }
        ],
        "venue": "Journal of orthopaedic surgery and research",
        "year": 2018
    },
    "KnqffYjh": {
        "id": "KnqffYjh",
        "title": "The proper timing of second-stage revision in treating periprosthetic knee infection: reliable indicators and risk factors.",
        "abstract": "The proper timing of re-implantation should be combined with disappearance of clinical symptoms and negative intraoperative FS with spacer detention time at 12 to 16\u00a0weeks.",
        "keywords": [
            "ESR",
            "Intraoperative frozen section",
            "Periprosthetic joint infection",
            "Serum CRP",
            "Total knee revision",
            "Two-stage revision"
        ],
        "authors": [
            {
                "name": "Jun Fu",
                "org": "Department of Orthopaedics, Chinese People's Liberation Army General Hospital (301 Hospital), Beijing, 100853, China."
            },
            {
                "name": "Ming Ni",
                "org": "Department of Orthopaedics, Chinese People's Liberation Army General Hospital (301 Hospital), Beijing, 100853, China."
            },
            {
                "name": "Heng Li",
                "org": "Department of Orthopaedics, Beijing Jishuitan Hospital, Beijing, China."
            },
            {
                "name": "Xiang Li",
                "org": "Department of Orthopaedics, Chinese People's Liberation Army General Hospital (301 Hospital), Beijing, 100853, China."
            },
            {
                "name": "Wei Chai",
                "org": "Department of Orthopaedics, Chinese People's Liberation Army General Hospital (301 Hospital), Beijing, 100853, China."
            },
            {
                "name": "Yonggang Zhou",
                "org": "Department of Orthopaedics, Chinese People's Liberation Army General Hospital (301 Hospital), Beijing, 100853, China."
            },
            {
                "name": "Libo Hao",
                "org": "Department of Orthopaedics, Chinese People's Liberation Army General Hospital (301 Hospital), Beijing, 100853, China."
            },
            {
                "name": "Jiying Chen",
                "org": "Department of Orthopaedics, Chinese People's Liberation Army General Hospital (301 Hospital), Beijing, 100853, China. hy76yuy@163.com."
            }
        ],
        "venue": "Journal of orthopaedic surgery and research",
        "year": 2018
    },
    "wme6V0aL": {
        "id": "wme6V0aL",
        "title": "3D-FE study on deformation behaviors in cold pilgering of high strength TA18 titanium alloy tube",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "heng li",
                "org": ""
            },
            {
                "name": "kaipeng shi",
                "org": ""
            },
            {
                "name": "he yang",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2013
    },
    "WDe4ltiG": {
        "id": "WDe4ltiG",
        "title": "BP artificial neural network modeling for accurate radius prediction and application in incremental in-plane bending",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "nan liu",
                "org": "northwestern polytechnical university"
            },
            {
                "name": "he yang",
                "org": "northwestern polytechnical university"
            },
            {
                "name": "heng li",
                "org": "northwestern polytechnical university"
            },
            {
                "name": "siliang yan",
                "org": "northwestern polytechnical university"
            },
            {
                "name": "honglie zhang",
                "org": "northwestern polytechnical university"
            },
            {
                "name": "wenting tang",
                "org": ""
            }
        ],
        "venue": "The International Journal of Advanced Manufacturing Technology",
        "year": 2015
    },
    "94zdgrZr": {
        "id": "94zdgrZr",
        "title": "Quasi-static tensile behavior of large-diameter thin-walled Ti\u20136Al\u20134V tubes at elevated temperature",
        "abstract": "",
        "keywords": [
            "fractography",
            "strain rate"
        ],
        "authors": [
            {
                "name": "zhijun tao",
                "org": ""
            },
            {
                "name": "he yang",
                "org": ""
            },
            {
                "name": "heng li",
                "org": ""
            },
            {
                "name": "xiaoguang fan",
                "org": ""
            }
        ],
        "venue": "Chinese Journal of Aeronautics",
        "year": 2015
    },
    "OkvhumST": {
        "id": "OkvhumST",
        "title": "Plastic wrinkling prediction in thin-walled part forming process: A review",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "nan liu",
                "org": ""
            },
            {
                "name": "he yang",
                "org": ""
            },
            {
                "name": "heng li",
                "org": ""
            },
            {
                "name": "siliang yan",
                "org": ""
            }
        ],
        "venue": "Chinese Journal of Aeronautics",
        "year": 2015
    },
    "GikdDz5f": {
        "id": "GikdDz5f",
        "title": "An imperfection-based perturbation method for plastic wrinkling prediction in tube bending under multi-die constraints",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "nan liu",
                "org": ""
            },
            {
                "name": "he yang",
                "org": ""
            },
            {
                "name": "heng li",
                "org": ""
            },
            {
                "name": "zhijun tao",
                "org": ""
            },
            {
                "name": "xiao hu",
                "org": ""
            }
        ],
        "venue": "International Journal of Mechanical Sciences",
        "year": 2015
    },
    "goiijZU0": {
        "id": "goiijZU0",
        "title": "The Integrated Digital Manufacture of Airplane Duct Based on through Process and Three Dimensional Modeling",
        "abstract": "",
        "keywords": [
            "duct"
        ],
        "authors": [
            {
                "name": "x d xu",
                "org": ""
            },
            {
                "name": "guang jun li",
                "org": ""
            },
            {
                "name": "he yang",
                "org": ""
            },
            {
                "name": "heng li",
                "org": ""
            },
            {
                "name": "mei zhan",
                "org": ""
            }
        ],
        "venue": "Advanced Materials Research",
        "year": 2012
    },
    "x13GquLx": {
        "id": "x13GquLx",
        "title": "A Multi-Objective Optimization Method for Thin-Walled Tube NC Bending",
        "abstract": "",
        "keywords": [
            "orthogonal array",
            "sequential quadratic programming"
        ],
        "authors": [
            {
                "name": "jie xu",
                "org": ""
            },
            {
                "name": "he yang",
                "org": ""
            },
            {
                "name": "heng li",
                "org": ""
            }
        ],
        "venue": "Advanced Materials Research",
        "year": 2011
    },
    "LEx3gLTt": {
        "id": "LEx3gLTt",
        "title": "Significance Analysis of Processing Parameters on Wall Thinning in Tube Bending",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "heng li",
                "org": ""
            },
            {
                "name": "kai peng shi",
                "org": ""
            },
            {
                "name": "he yang",
                "org": ""
            },
            {
                "name": "yu li tian",
                "org": ""
            }
        ],
        "venue": "Advanced Materials Research",
        "year": 2012
    },
    "0NIbqofN": {
        "id": "0NIbqofN",
        "title": "Constitutive modeling of compression behavior of TC4 tube based on modified Arrhenius and artificial neural network models",
        "abstract": "Warm rotary draw bending provides a feasible method to form the large-diameter thin-walled (LDTW) TC4 bent tubes, which are widely used in the pneumatic system of aircrafts. An accurate prediction of flow behavior of TC4 tubes considering the couple effects of temperature, strain rate and strain is critical for understanding the deformation behavior of metals and optimizing the processing parameters in warm rotary draw bending of TC4 tubes. In this study, isothermal compression tests of TC4 tube alloy were performed from 573 to 873 K with an interval of 100 K and strain rates of 0.001, 0.010 and 0.100 s\u22121. The prediction of flow behavior was done using two constitutive models, namely modified Arrhenius model and artificial neural network (ANN) model. The predictions of these constitutive models were compared using statistical measures like correlation coefficient (R), average absolute relative error (AARE) and its variation with the deformation parameters (temperature, strain rate and strain). Analysis of statistical measures reveals that the two models show high predicted accuracy in terms of R and AARE. Comparatively speaking, the ANN model presents higher predicted accuracy than the modified Arrhenius model. In addition, the predicted accuracy of ANN model presents high stability at the whole deformation parameter ranges, whereas the predictability of the modified Arrhenius model has some fluctuation at different deformation conditions. It presents higher predicted accuracy at temperatures of 573\u2013773 K, strain rates of 0.010\u20130.100 s\u22121 and strain of 0.04\u20130.32, while low accuracy at temperature of 873 K, strain rates of 0.001 s\u22121 and strain of 0.36\u20130.48. Thus, the application of modified Arrhenius model is limited by its relatively low predicted accuracy at some deformation conditions, while the ANN model presents very high predicted accuracy at all deformation conditions, which can be used to study the compression behavior of TC4 tube at the temperature range of 573\u2013873 K and the strain rate of 0.001\u20130.100 s\u22121. It can provide guideline for the design of processing parameters in warm rotary draw bending of LDTW TC4 tubes.",
        "keywords": "",
        "authors": [
            {
                "name": "Zhijun Tao",
                "org": "Northwestern Polytechnical University"
            },
            {
                "name": "He Yang",
                "org": "Northwestern Polytechnical University"
            },
            {
                "name": "Heng Li",
                "org": "Northwestern Polytechnical University"
            },
            {
                "name": "Jun Ma",
                "org": "Northwestern Polytechnical University"
            },
            {
                "name": "Peng-Fei Gao",
                "org": "Northwestern Polytechnical University"
            }
        ],
        "venue": "Rare Metals",
        "year": 2016
    },
    "CBIp0bL3": {
        "id": "CBIp0bL3",
        "title": "Characterizing of Anisotropy and Asymmetry of Tubular Materials",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": "Northwestern Polytechnical University"
            },
            {
                "name": "Heng Yang",
                "org": "Northwestern Polytechnical University"
            },
            {
                "name": "Jun Ma",
                "org": "Northwestern Polytechnical University"
            },
            {
                "name": "Zhen Yong Feng",
                "org": "Northwestern Polytechnical University"
            }
        ],
        "venue": "Materials Science Forum",
        "year": 2018
    },
    "ejVdaaLQ": {
        "id": "ejVdaaLQ",
        "title": "A modified Johnson\u2013Cook model for NC warm bending of large diameter thin-walled Ti\u20136Al\u20134V tube in wide ranges of strain rates and temperatures",
        "abstract": "Abstract   Numerical control (NC) warm bending is a proven strategy to form the large diameter thin-walled (LDTW) Ti\u20136Al\u20134V tubes, which are typical light-weight and high-performance structural components urgently required in many industries. In virtue of unveiling the thermo-mechanical coupled deformation behaviors, uniaxial tensile tests were conducted on Ti\u20136Al\u20134V tube within wide ranges of temperatures (25\u2013600 \u00b0C) and strain rates (0.00067\u20130.1 s \u22121 ). Moreover, a modified Johnson\u2013Cook (JC) model is proposed with a consideration of nonlinear strain rate hardening and the interaction between strain hardening and thermal softening. Resultantly, the present model gives more accurate predictions for flow stress over the entire deformation ranges and the maximum error decreases by about 90%. By employing proposed model to NC warm bending, preferable precision is obtained in predicting forming defects including fracture, wrinkling and over thinning. The present work lays foundation for the forming limit prediction and process optimization in NC warm bending of LDTW Ti\u20136Al\u20134V tubes.",
        "keywords": "",
        "authors": [
            {
                "name": "Zhi-jun Tao",
                "org": "State Key Laboratory of Solidification Processing, School of Materials Science and Engineering, Northwestern Polytechnical University, Xi'an 710072, China"
            },
            {
                "name": "Xiao-guang Fan",
                "org": "State Key Laboratory of Solidification Processing, School of Materials Science and Engineering, Northwestern Polytechnical University, Xi'an 710072, China"
            },
            {
                "name": "He Yang",
                "org": "State Key Laboratory of Solidification Processing, School of Materials Science and Engineering, Northwestern Polytechnical University, Xi'an 710072, China"
            },
            {
                "name": "Jun Ma",
                "org": "State Key Laboratory of Solidification Processing, School of Materials Science and Engineering, Northwestern Polytechnical University, Xi'an 710072, China"
            },
            {
                "name": "Heng Li",
                "org": "State Key Laboratory of Solidification Processing, School of Materials Science and Engineering, Northwestern Polytechnical University, Xi'an 710072, China"
            }
        ],
        "venue": "Transactions of Nonferrous Metals Society of China",
        "year": 2018
    },
    "Y9kzleGv": {
        "id": "Y9kzleGv",
        "title": "Constitutive modeling related uncertainties: Effects on deformation prediction accuracy of sheet metallic materials",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Yang",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Jun Ma",
                "org": ""
            },
            {
                "name": "Zhao Zhang",
                "org": ""
            },
            {
                "name": "Jun Chen",
                "org": ""
            }
        ],
        "venue": "International Journal of Mechanical Sciences",
        "year": 2019
    },
    "0NqKLXOj": {
        "id": "0NqKLXOj",
        "title": "Experimental identification of thermal induced warpage in polymer-metal composite films.",
        "abstract": "Abstract   Composite thick films consisting of multi-layered polymers and metals are widely used in integrated circuits(IC) and its packaging, and it arises intricate stress and warpage problems due to complex inner stress distribution and evolution. The wafer warpage origination and evolution of multi-layered polyimide (PI)/Cu composite film is measured in-situ by a Multi-beam Laser Optical Sensor (MOS) system. Itu0027s found that PI has an intricate influence on wafer warpage evolution and Cu plastic deformation due to viscoelasticity and glass-transition, and the influence differs in different structures and at different temperatures. Nonlinearity of the curvature\u2013temperature curve of the composite occurs at much lower temperature than in single PI or Cu film, showing mutual effect of PI and Cu. Unlike bare or capping PI film that totally stress relaxed at high temperature, bottom PI coated by Cu film sustains a medium compressive stress, indicating that Cu coating film has restrained stress relaxation of PI. The warpage evolution during heating is different from that during cooling, perhaps due to different deformation mechanism.",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Chunsheng Zhu",
                "org": ""
            },
            {
                "name": "Gaowei Xu",
                "org": ""
            },
            {
                "name": "Le Luo",
                "org": ""
            }
        ],
        "venue": "Microelectronics Reliability",
        "year": 2016
    },
    "b2ZQensj": {
        "id": "b2ZQensj",
        "title": "Influence of polyimide on thermal stress evolution in polyimide/Cu thick film composite",
        "abstract": "Polyimide(PI)/Cu composite thick films are widely used in wafer level packaging (WLP), and a common problem is the defects such as void, delamination, crack or wafer warpage induced by thermal stress. Compared with traditional rigid substrate/Cu/passivation system, PI imposes quite a different boundary constraint on Cu, resulting in a special stress evolution, and the corresponding mechanism is far from fully understood. Five sets of composites are constructed to investigate the influence of PI on thermal stress evolution in Cu film by means of in situ wafer warpage measurement under thermal cycling. Together with finite element analyses, it\u2019s counterintuitive to find that although PI indeed reduces the stress in Cu, it exacerbates overall wafer warpage at room temperature. Warpage evolution reveals that composites consisting of substrate/PI/Cu sustains a moderate compressive stress while bare PI film is totally stress relaxed at high temperature, indicating that Cu and PI restrains stress relaxation reciprocally. It suggests that mutual effect should be considered when evaluating the stress distribution in polymer-metal composite thick films.",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": "Chinese Academy of Sciences (CAS)"
            },
            {
                "name": "Gong Cheng",
                "org": "Chinese Academy of Sciences (CAS)"
            },
            {
                "name": "Gaowei Xu",
                "org": "Chinese Academy of Sciences (CAS)"
            },
            {
                "name": "Le Luo",
                "org": "Chinese Academy of Sciences (CAS)"
            }
        ],
        "venue": "Journal of Materials Science: Materials in Electronics",
        "year": 2016
    },
    "eOTs7meP": {
        "id": "eOTs7meP",
        "title": "Explore of warpage origination in WLP and processing influence factors by experiment and theoretical modeling",
        "abstract": "Thick Cu films are widely used in wafer level packaging, and the stress evolution during subsequent thermal cycling as well as the induced wafer warpage may make a significant impact on product yielding and needs to be investigated. The stress evolution behavior of 5 \u03bcm thick as-electroplated Cu films during thermal cycling are in situ investigated by wafer warpage measurement. It is revealed by microstructure analyses that the grain growth during thermal cycling is ignorable in current work, but dramatic atomic diffusion has occurred, suggesting the deformation mechanism is dominated by diffusional creep. As the dominant diffusion mechanism differs at different temperatures, an equivalent diffusional energy that has a linearly correlation to temperature is proposed, and consequently a stress evolution model based on the equivalent diffusional energy is deduced. Compared with conventional work, the current model has fewer fitted parameters, and shows better agreement with the experiment results.",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": "Chinese Academy of Sciences (CAS)"
            },
            {
                "name": "Gong Cheng",
                "org": "Chinese Academy of Sciences (CAS)"
            },
            {
                "name": "Gaowei Xu",
                "org": "Chinese Academy of Sciences (CAS)"
            },
            {
                "name": "Le Luo",
                "org": "Chinese Academy of Sciences (CAS)"
            }
        ],
        "venue": "Journal of Materials Science: Materials in Electronics",
        "year": 2016
    },
    "76zEDTS2": {
        "id": "76zEDTS2",
        "title": "The Nonlinearity of Stress Evolution in Polymer-Metal Composite Thin Films During Thermal Treatment",
        "abstract": "Composite thin films consisting of multi-layered polymers and metals are widely used in integrated circuits(IC) and its packaging, and it arises intricate wafer warpage problems due to complex inner stress distribution and evolution. The wafer warpage origination and mechanism of a multi-layered polymer-metal composite thin film is identified and analyzed in this paper. Different PI/Cu composite structures are employed to characterize the composite filmu0027s thermal mechanism. The wafer warpage evolution during thermal process is measured in-situ by a Multi-beam Laser Optical Sensor system. Itu0027s found that the cure shrinkage process of PI at evaluated temperature has little effect on wafer warpage in this work, however, the coefficient of thermal expansion (CTE) mismatch between the deposited materials contributes to major warpage during cooling to room temperature (RT). Despite the fact that PI cushions impact stress, it exacerbates overall warpage at RT in proportion to thickness. The ECD Cu embedded in PI also accounts for a substantial proportion to overall wafer warpage and leads to a hysteresis loop during the thermal processes, indicating plastic deformation such as grain growth or surficial diffusion or grain boundary diffusion, and the hysteresis can be largely inhibited by PI layers.",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": "Chinese Academy of Sciences"
            },
            {
                "name": "Gong Cheng",
                "org": ""
            },
            {
                "name": "Gaowei Xu",
                "org": "Chinese Academy of Sciences"
            },
            {
                "name": "Le Luo",
                "org": "Chinese Academy of Sciences"
            }
        ],
        "venue": "electronic components and technology conference",
        "year": 2016
    },
    "a2Tl88Xu": {
        "id": "a2Tl88Xu",
        "title": "Controllable large scaled nanotwin formation in Cu film at lower temperatures",
        "abstract": "By means of low temperature rapid annealing, it is found that an abrupt thermal stress relaxation occurs in Cu film at the beginning of cooling, which greatly increases the driving force for twin nucleation and growth. Consequently, high-density nanotwins (nt) are successfully produced in as-plated Cu film at wafer-level under temperatures as low as 300 \u00b0C, which is much lower than conventional processes (above 550 \u00b0C), making it fully compatible with the semiconductor industry. This enhanced annealing processing provides not only a cost-effective approach for large scaled void-free nt-Cu synthesis together with half-quantitatively controllable twin spacing, but demonstrates the prospect and significance of inconspicuous annealed nanotwins on the application of microelectronics.",
        "keywords": "",
        "authors": [
            {
                "name": "Gong Cheng",
                "org": "State Key Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences (CAS), 200050 Shanghai, People\u2019s Republic of China"
            },
            {
                "name": "Heng Li",
                "org": "State Key Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences (CAS), 200050 Shanghai, People\u2019s Republic of China"
            },
            {
                "name": "Weibo Zhang",
                "org": "State Key Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences (CAS), 200050 Shanghai, People\u2019s Republic of China"
            },
            {
                "name": "Gaowei Xu",
                "org": "State Key Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences (CAS), 200050 Shanghai, People\u2019s Republic of China"
            },
            {
                "name": "Le Luo",
                "org": "State Key Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences (CAS), 200050 Shanghai, People\u2019s Republic of China"
            }
        ],
        "venue": "Journal of Physics D",
        "year": 2016
    },
    "T3ImGCH5": {
        "id": "T3ImGCH5",
        "title": "Effects of thickness on optical characteristics and strain distribution of thin-film GaN light-emitting diodes transferred to Si substrates",
        "abstract": "We investigated the effect of device thickness on the internal quantum efficiency (IQE) of thin-film GaN light-emitting diodes (LEDs), which were grown on Si substrates and transferred to other Si substrates with reduced film thickness. It was confirmed by Raman spectroscopy and photoluminescence measurement that the compressive strain is released and the quantum-confined Stark effect (QCSE) is suppressed after reducing the thickness. The best IQE of 62.9% was reached with a large suppression of the band tilting by QCSE, from 7.9 meV in the original structure to 2.4 meV in the thinnest sample, and this value can compete with that of GaN-based LEDs grown on a sapphire substrate.",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": "Department of Photonics, National Chiao Tung University, Hsinchu 300, Taiwan"
            },
            {
                "name": "Yang-Da Shi",
                "org": "Department of Photonics, National Chiao Tung University, Hsinchu 300, Taiwan"
            },
            {
                "name": "Meixin Feng",
                "org": "Key Laboratory of Nanodevices and Applications, Chinese Academy of Sciences (CAS), Suzhou 215123, China"
            },
            {
                "name": "Qian Sun",
                "org": ""
            },
            {
                "name": "Tien-Chang Lu",
                "org": "Department of Photonics, National Chiao Tung University, Hsinchu 300, Taiwan"
            }
        ],
        "venue": "Applied Physics Express",
        "year": 2016
    },
    "Vif917Gy": {
        "id": "Vif917Gy",
        "title": "3D structural construction of GaN-based light emitting diode by confocal micro-Raman spectroscopy",
        "abstract": "The key issue for light emission strength of GaN-based LEDs is the high defect density and strain in MQWs causing the electric polarization fields. In this work, we construct 3D confocal microspectroscopy to clarify strain distribution and the relationship between photoluminescence (PL) intensity and pattern sapphire substrate (PSS). From 3D construction of E 2  high  Raman and PL mapping, the dislocation in MQW can be traced to the cone tip of PSS and the difference in E 2  high  Raman mapping between substrate and surface is also measured. The ability to measure strain change in 3D structure nondestructively can be applied to explore many structural problems of GaN-based optoelectronic devices.",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Chiao-Yun Chang",
                "org": "National Chiao Tung Univ. (Taiwan)"
            },
            {
                "name": "Hui-Yu Cheng",
                "org": "National Taiwan Univ. (Taiwan)"
            },
            {
                "name": "Wei-Liang Chen",
                "org": "National Taiwan Univ. (Taiwan)"
            },
            {
                "name": "Yi-Hsin Huang",
                "org": "National Taiwan Univ. (Taiwan)"
            },
            {
                "name": "Tien-Chang Lu",
                "org": "National Chiao Tung Univ. (Taiwan)"
            },
            {
                "name": "Yu-Ming Chang",
                "org": "National Taiwan Univ. (Taiwan)"
            }
        ],
        "venue": "Proceedings of SPIE",
        "year": 2016
    },
    "qqCExhIY": {
        "id": "qqCExhIY",
        "title": "Significant improvement of GaN crystal quality with ex-situ sputtered AlN nucleation layers",
        "abstract": "Ex-situ sputtered AlN nucleation layer has been demonstrated effective to significantly improve crystal quality and electrical properties of GaN epitaxy layers for GaN based Light-emitting diodes (LEDs). In this report, we have successfully reduced X-ray (102) FWHM from 240 to 110 arcsec, and (002) FWHM from 230 to 101 arcsec. In addition, reverse-bias voltage (Vr) increased around 20% with the sputtered AlN nucleation layer. Furthermore, output power of LEDs grown on sputtered AlN nucleation layer can be improved around 4.0% compared with LEDs which is with conventional GaN nucleation layer on pattern sapphire substrate (PSS).",
        "keywords": "",
        "authors": [
            {
                "name": "Shuo-Wei Chen",
                "org": "National Chiao Tung Univ. (Taiwan)"
            },
            {
                "name": "Young Yang",
                "org": "Epistar Corp. (Taiwan)"
            },
            {
                "name": "Wei-Chih Wen",
                "org": "Epistar Corp. (Taiwan)"
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Tien-Chang Lu",
                "org": "National Chiao Tung Univ. (Taiwan)"
            }
        ],
        "venue": "Proceedings of SPIE",
        "year": 2016
    },
    "90XXx4O7": {
        "id": "90XXx4O7",
        "title": "Improved performance of GaN based light emitting diodes with ex-situ sputtered AlN nucleation layers",
        "abstract": "The crystal quality, electrical and optical properties of GaN based light emitting diodes (LEDs) with ex-situ sputtered physical vapor deposition (PVD) aluminum nitride (AlN) nucleation layers were investigated. It was found that the crystal quality in terms of defect density and x-ray diffraction linewidth was greatly improved in comparison to LEDs with in-situ low temperature GaN nucleation layer. The light output power was 3.7% increased and the reverse bias voltage of leakage current was twice on LEDs with ex-situ PVD AlN nucleation layers. However, larger compressive strain was discovered in LEDs with ex-situ PVD AlN nucleation layers. The study shows the potential and constrain in applying ex-situ PVD AlN nucleation layers to fabricate high quality GaN crystals in various optoelectronics.",
        "keywords": "",
        "authors": [
            {
                "name": "Shuo-Wei Chen",
                "org": "Department of Photonics, National Chiao Tung University, Hsinchu 300, Taiwan"
            },
            {
                "name": "Shuo-Wei Chen",
                "org": "Department of Photonics, National Chiao Tung University, Hsinchu 300, Taiwan"
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Tien-Chang Lu",
                "org": "Department of Photonics, National Chiao Tung University, Hsinchu 300, Taiwan"
            }
        ],
        "venue": "AIP Advances",
        "year": 2016
    },
    "wfk5T3vz": {
        "id": "wfk5T3vz",
        "title": "3D numerical modeling of the carrier transport and radiative efficiency for InGaN/GaN light emitting diodes with V-shaped pits",
        "abstract": "In this paper, influence of a V-pit embedded inside the multiple quantum wells (MQWs) LED was studied. A fully three-dimensional stress-strain solver and Poisson-drift-diffusion solver are employed to study the current path, where the quantum efficiency and turn-on voltage will be discussed. Our results show that the hole current is not only from top into lateral quantum wells (QWs) but flowing through shallow sidewall QWs and then injecting into the deeper lateral QWs in V-pit structures, where the V-pit geometry provides more percolation length for holes to make the distribution uniform along lateral MQWs. The IQE behavior with different V-pit sizes, threading dislocation densities, and current densities were analyzed. Substantially, the variation of the quantum efficiency for different V-pit sizes is due to the trap-assisted nonradiative recombination, effective QW ratio, and ability of hole injections.",
        "keywords": "",
        "authors": [
            {
                "name": "Chi-Kang Li",
                "org": "Graduate Institute of Photonics and Optoelectronics and Department of Electrical Engineering, National Taiwan University, Taipei, 10617, Taiwan"
            },
            {
                "name": "Chen-Kuo Wu",
                "org": "Graduate Institute of Photonics and Optoelectronics and Department of Electrical Engineering, National Taiwan University, Taipei, 10617, Taiwan"
            },
            {
                "name": "Chung-Cheng Hsu",
                "org": "Graduate Institute of Photonics and Optoelectronics and Department of Electrical Engineering, National Taiwan University, Taipei, 10617, Taiwan"
            },
            {
                "name": "Li-Shuo Lu",
                "org": "Graduate Institute of Photonics and Optoelectronics and Department of Electrical Engineering, National Taiwan University, Taipei, 10617, Taiwan"
            },
            {
                "name": "Heng Li",
                "org": "Department of Photonics and Institute of Electro-Optical Engineering, National Chiao-Tung University, Hsinchu 30050, Taiwan"
            },
            {
                "name": "Tien-Chang Lu",
                "org": "Department of Photonics and Institute of Electro-Optical Engineering, National Chiao-Tung University, Hsinchu 30050, Taiwan"
            },
            {
                "name": "Yuh-Renn Wu",
                "org": "Graduate Institute of Photonics and Optoelectronics and Department of Electrical Engineering, National Taiwan University, Taipei, 10617, Taiwan"
            }
        ],
        "venue": "AIP Advances",
        "year": 2016
    },
    "UKetDDvl": {
        "id": "UKetDDvl",
        "title": "Rapid separation of gold nanorods in multilayer aqueous systems via centrifugation",
        "abstract": "In this work, we demonstrate multilayer aqueous systems as media to separate gold nanoparticles of different shapes and sizes. The multilayer aqueous systems are composed of CTAB/EG solutions with different viscosities. By centrifugation, gold nanoparticles with different shapes and sizes can be dispersed in different layers of the aqueous systems. Gold nanorods synthesized by different conditions, such as changing the amount of AgNO3 or different aging times, are used to examine the multilayer aqueous systems. Gold nanorods with higher aspect ratios can be obtained by increasing the concentration of AgNO3, as confirmed by UV-Vis spectra and TEM studies. The separated gold nanorods are also characterized by surface-enhanced Raman scattering (SERS), showing lower activity for gold nanorods with higher aspect ratios, due to the size-dependent absorption of the longitudinal plasmon band. The multilayer aqueous systems can effectively separate gold nanorods prepared by different conditions and can be applied to separate other types of nanoparticles.",
        "keywords": "",
        "authors": [
            {
                "name": "I-Chun Yao",
                "org": "Department of Applied Chemistry, National Chiao Tung University,Hsinchu,Taiwan 30010"
            },
            {
                "name": "Chun-Wei Chang",
                "org": "Department of Applied Chemistry, National Chiao Tung University,Hsinchu,Taiwan 30010"
            },
            {
                "name": "Hao-Wen Ko",
                "org": "Department of Applied Chemistry, National Chiao Tung University,Hsinchu,Taiwan 30010"
            },
            {
                "name": "Heng Li",
                "org": "Department of Photonics, National Chiao Tung University,Hsinchu,Taiwan 30010"
            },
            {
                "name": "Tien-Chang Lu",
                "org": "Department of Photonics, National Chiao Tung University,Hsinchu,Taiwan 30010"
            },
            {
                "name": "Jiun-Tai Chen",
                "org": "Department of Applied Chemistry, National Chiao Tung University,Hsinchu,Taiwan 30010"
            }
        ],
        "venue": "RSC Advances",
        "year": 2016
    },
    "r0e5TuL6": {
        "id": "r0e5TuL6",
        "title": "Superior characteristics of microscale light emitting diodes through tightly lateral oxide-confined scheme",
        "abstract": "We report on the design of the geometry and chip size\u2013controlled structures of microscale light-emitting diodes (micro-LEDs) with a shallow-etched oxide-refilled current aperture and their performance. The proposed structure, which combines an indium-tin-oxide layer and an oxide-confined aperture, exhibited not only uniform current distribution but also remarkably tight current confinement. An extremely high injection level of more than 90\u2009kA/cm2 was achieved in the micro-LED with a 5-\u03bcm aperture. Current spreading and the droop mechanism in the investigated devices were characterized through electroluminescence measurements, optical microscopy, and beam-view imaging. Furthermore, we utilized the \u03b2-model and S-model to elucidate current crowding and the efficiency droop phenomenon in the investigated micro-LEDs. The luminescence results evidenced the highly favorable performance of the fabricated micro-LEDs, which is a result of their more uniform current spreading and lower junction temperature relative ...",
        "keywords": "",
        "authors": [
            {
                "name": "Shen-Che Huang",
                "org": "Department of Photonics and Institute of Electro-Optical Engineering, National Chiao Tung University, 1001 Ta-Hsueh Rd., Hsinchu 30010, Taiwan"
            },
            {
                "name": "Heng Li",
                "org": "Department of Photonics and Institute of Electro-Optical Engineering, National Chiao Tung University, 1001 Ta-Hsueh Rd., Hsinchu 30010, Taiwan"
            },
            {
                "name": "Zhe-Han Zhang",
                "org": "Department of Photonics and Institute of Electro-Optical Engineering, National Chiao Tung University, 1001 Ta-Hsueh Rd., Hsinchu 30010, Taiwan"
            },
            {
                "name": "Hsiang Chen",
                "org": ""
            },
            {
                "name": "Shing-Chung Wang",
                "org": "Department of Photonics and Institute of Electro-Optical Engineering, National Chiao Tung University, 1001 Ta-Hsueh Rd., Hsinchu 30010, Taiwan"
            },
            {
                "name": "Tien-Chang Lu",
                "org": "Department of Photonics and Institute of Electro-Optical Engineering, National Chiao Tung University, 1001 Ta-Hsueh Rd., Hsinchu 30010, Taiwan"
            }
        ],
        "venue": "Applied Physics Letters",
        "year": 2017
    },
    "cQAaLgVP": {
        "id": "cQAaLgVP",
        "title": "Three dimensional characterization of GaN-based light emitting diode grown on patterned sapphire substrate by confocal Raman and photoluminescence spectromicroscopy",
        "abstract": "Three dimensional characterization of GaN-based light emitting diode grown on patterned sapphire substrate by confocal Raman and photoluminescence spectromicroscopy",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Hui-Yu Cheng",
                "org": ""
            },
            {
                "name": "Wei-Liang Chen",
                "org": ""
            },
            {
                "name": "Yi-Hsin Huang",
                "org": ""
            },
            {
                "name": "Chi-Kang Li",
                "org": ""
            },
            {
                "name": "Chiao-Yun Chang",
                "org": ""
            },
            {
                "name": "Yuh-Renn Wu",
                "org": ""
            },
            {
                "name": "Tien-Chang Lu",
                "org": ""
            },
            {
                "name": "Yu-Ming Chang",
                "org": ""
            }
        ],
        "venue": "Scientific Reports",
        "year": 2017
    },
    "YZ52R6ob": {
        "id": "YZ52R6ob",
        "title": "Reliability analysis of GaN-based UVLEDs under forward bias operations in salty vapor environment",
        "abstract": "We illustrated the reliability of longer wavelength ultraviolet light-emitting diodes (UVLEDs) in salty vapour environment under manipulation of forward-bias stress via consistent electrical and material characterizations. By manipulating the unprecedented operation in salty vapour ambient, we investigated a series of remarkable findings related to origin of failure behaviours.",
        "keywords": "",
        "authors": [
            {
                "name": "Shen-Che Huang",
                "org": "Department of Photonics, National Chiao Tung University, 1001, Ta-Hsueh Road, East District, Hsinchu City 30010, Taiwan"
            },
            {
                "name": "Heng Li",
                "org": "Department of Photonics, National Chiao Tung University, 1001, Ta-Hsueh Road, East District, Hsinchu City 30010, Taiwan"
            },
            {
                "name": "Yu-Shan Lee",
                "org": "Department of Applied Materials and Optoelectronic Engineering, National Chi Nan University"
            },
            {
                "name": "Chen-Hao Hung",
                "org": "Department of Applied Materials and Optoelectronic Engineering, National Chi Nan University"
            },
            {
                "name": "Shing-Chung Wang",
                "org": "Department of Photonics, National Chiao Tung University, 1001, Ta-Hsueh Road, East District, Hsinchu City 30010, Taiwan"
            },
            {
                "name": "Hsiang Chen",
                "org": ""
            },
            {
                "name": "Tien-Chang Lu",
                "org": "Department of Photonics, National Chiao Tung University, 1001, Ta-Hsueh Road, East District, Hsinchu City 30010, Taiwan"
            }
        ],
        "venue": "microoptics conference",
        "year": 2017
    },
    "i3IY6Rw7": {
        "id": "i3IY6Rw7",
        "title": "Three dimensional compressive strain and its effect on optical properties of GaN-based light emitting diode grown on patterned sapphire substrate by confocal spectromicroscopy",
        "abstract": "We performed depth-resolved spectral mappings of GaN-based LED and results showed that the strain distribution propagating from PSS-GaN heterointerface toward surface and the PL intensity are spatially correlated. Numerical simulation based on indium composition distribution led to a radiative recombination rate distribution shows agreement with the experimental PL intensity distribution.",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": "Dept. of Photonics & Institute of Electro-Optical Engineering, National Chiao Tung University, 1001, University street, Hsinchu 30050, Taiwan"
            },
            {
                "name": "Hui-Yu Cheng",
                "org": "Center for Condensed Matter Sciences, National Taiwan University"
            },
            {
                "name": "Wei-Liang Chen",
                "org": "Center for Condensed Matter Sciences, National Taiwan University"
            },
            {
                "name": "Yi-Hsin Huang",
                "org": "Center for Condensed Matter Sciences, National Taiwan University"
            },
            {
                "name": "Chi-Kang Li",
                "org": "Graduate Institute of Photonics and Optoelectronics and Department of Electrical Engineering, National Taiwan University"
            },
            {
                "name": "Chiao-Yun Chang",
                "org": "Dept. of Photonics & Institute of Electro-Optical Engineering, National Chiao Tung University, 1001, University street, Hsinchu 30050, Taiwan"
            },
            {
                "name": "Yuh-Renn Wu",
                "org": "Graduate Institute of Photonics and Optoelectronics and Department of Electrical Engineering, National Taiwan University"
            },
            {
                "name": "Tien-Chang Lu",
                "org": "Dept. of Photonics & Institute of Electro-Optical Engineering, National Chiao Tung University, 1001, University street, Hsinchu 30050, Taiwan"
            },
            {
                "name": "Yu-Ming Chang",
                "org": "Center for Condensed Matter Sciences, National Taiwan University"
            }
        ],
        "venue": "microoptics conference",
        "year": 2017
    },
    "bGhh18mD": {
        "id": "bGhh18mD",
        "title": "Design of photonic crystal surface emitting lasers with indium-tin-oxide top claddings",
        "abstract": "Electrically pumped GaAs-based photonic crystal surface emitting lasers were fabricated using a simple fabrication process by directly capping the indium-tin-oxide transparent conducting thin film as the top cladding layer upon a photonic crystal layer. Optimization of the separate-confinement heterostructures of a laser structure is crucial to improving characteristics by providing advantageous optical confinements. The turn-on voltage, series resistance, threshold current, and slope efficiency of the laser with a 100\u2009\u00d7\u2009100\u2009\u03bcm2 photonic crystal area operated at room temperature were 1.3\u2009V, 1.5\u2009\u03a9, 121\u2009mA, and 0.2\u2009W/A, respectively. Furthermore, we demonstrated a single-lobed lasing wavelength of 928.6\u2009nm at 200\u2009mA and a wavelength redshift rate of 0.05\u2009nm/K in temperature-dependent measurements. The device exhibited the maximum output power of approximately 400 mW at an injection current of 2\u2009A; moreover, divergence angles of less than 1\u00b0 for the unpolarized circular-shaped laser beam were measured at var...",
        "keywords": "",
        "authors": [
            {
                "name": "Shen-Che Huang",
                "org": "Department of Photonics, College of Electrical and Computer Engineering, National Chiao Tung University, 1001 Ta-Hsueh Rd., Hsinchu 30010, Taiwan"
            },
            {
                "name": "Kuo-Bin Hong",
                "org": "Department of Photonics, College of Electrical and Computer Engineering, National Chiao Tung University, 1001 Ta-Hsueh Rd., Hsinchu 30010, Taiwan"
            },
            {
                "name": "Han-Lun Chiu",
                "org": "Department of Photonics, College of Electrical and Computer Engineering, National Chiao Tung University, 1001 Ta-Hsueh Rd., Hsinchu 30010, Taiwan"
            },
            {
                "name": "Shao-Wun Lan",
                "org": "Department of Photonics, College of Electrical and Computer Engineering, National Chiao Tung University, 1001 Ta-Hsueh Rd., Hsinchu 30010, Taiwan"
            },
            {
                "name": "Tsu-Chi Chang",
                "org": "Department of Photonics, College of Electrical and Computer Engineering, National Chiao Tung University, 1001 Ta-Hsueh Rd., Hsinchu 30010, Taiwan"
            },
            {
                "name": "Heng Li",
                "org": "Department of Photonics, College of Electrical and Computer Engineering, National Chiao Tung University, 1001 Ta-Hsueh Rd., Hsinchu 30010, Taiwan"
            },
            {
                "name": "Tien-Chang Lu",
                "org": "Department of Photonics, College of Electrical and Computer Engineering, National Chiao Tung University, 1001 Ta-Hsueh Rd., Hsinchu 30010, Taiwan"
            }
        ],
        "venue": "Applied Physics Letters",
        "year": 2018
    },
    "POHwr1HU": {
        "id": "POHwr1HU",
        "title": "Flexible Organometal-Halide Perovskite Lasers for Speckle Reduction in Imaging Projection.",
        "abstract": "Disorder is emerging as a strategy for fabricating random laser sources with very promising materials, like perovskites, for which standard laser cavities are not effective, or too expensive. We need however different fabrication protocols and technologies for reducing the laser threshold and controlling its emission. Here we demonstrate an effectively solvent-engineered method for high quality perovskite thin films on the flexible polyimide substrate. The fractal perovskite thin films exhibit excellent optical properties at room temperature and easily achieve lasing action without any laser cavity above room temperature with a low pumping threshold. The lasing action is also observed in curved perovskite thin films on the flexible substrates. The lasing threshold can be further reduced by increasing the local curvature, which modifies the scattering strengths of the bent thin film. We also show that the curved perovskite lasers are extremely robust with respect to repeated deformations. Because of the low spatial coherence, these curved random laser devices are efficient and durable speckle-free light sources for applications in spectroscopy, bio-imaging and illumination.",
        "keywords": "",
        "authors": [
            {
                "name": "Yu-Chi Wang",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Yu-Heng Hong",
                "org": ""
            },
            {
                "name": "Kuo-Bin Hong",
                "org": ""
            },
            {
                "name": "Fang-Chung Chen",
                "org": ""
            },
            {
                "name": "Chia-Hung Hsu",
                "org": ""
            },
            {
                "name": "Ray-Kuang Lee",
                "org": ""
            },
            {
                "name": "Claudio Conti",
                "org": ""
            },
            {
                "name": "Tsung Sheng Kao",
                "org": ""
            },
            {
                "name": "Tien-Chang Lu",
                "org": ""
            }
        ],
        "venue": "ACS nano",
        "year": 2019
    },
    "bxkStxS7": {
        "id": "bxkStxS7",
        "title": "Improved Performance of Near UV GaN-Based Light Emitting Diodes With Asymmetric Triangular Multiple Quantum Wells",
        "abstract": "Near-ultraviolet (NUV) light-emitting diodes (LEDs) have been used in several potential applications such as UV curing and biochemical sensors. However, the internal quantum efficiency (IQE) of NUV-LEDs is still a crucial issue. To improve the IQE, in this paper, an asymmetric triangular multiple quantum well (MQW) structure was used, which exhibited a higher emission efficiency and lower efficiency droop with nitrogen face-oriented inclination. This is in contrast to the trend observed in blue LEDs. Furthermore, we demonstrated that holes are more confined in MQWs with nitrogen face-oriented inclination than in MQWs with gallium face-oriented inclination. Moreover, simulations revealed that the IQE improved by approximately 32% compared with that of symmetric square MQW NUV-LEDs; this trend was also confirmed through experimental results. The external quantum efficiency of thin-film flip-chip LEDs with nitrogen face-oriented inclination MQWs was 52%.",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": "Department of Photonics, National Chiao Tung University, Hsinchu, Taiwan"
            },
            {
                "name": "Chia-Jui Chang",
                "org": "Department of Photonics, National Chiao Tung University, Hsinchu, Taiwan"
            },
            {
                "name": "Shiou-Yi Kuo",
                "org": "Department of Photonics, National Chiao Tung University, Hsinchu, Taiwan"
            },
            {
                "name": "Hao-Cheng Wu",
                "org": "Engineering Research Center for Optoelectronics of Guangdong Province, School of Physics and Optoelectronics, South China University of Technology, Guangzhou, China"
            },
            {
                "name": "Huamao Huang",
                "org": "Engineering Research Center for Optoelectronics of Guangdong Province, School of Physics and Optoelectronics, South China University of Technology, Guangzhou, China"
            },
            {
                "name": "Tien-Chang Lu",
                "org": "Department of Photonics, National Chiao Tung University, Hsinchu, Taiwan"
            }
        ],
        "venue": "IEEE Journal of Quantum Electronics",
        "year": 2019
    },
    "P2RVMJjt": {
        "id": "P2RVMJjt",
        "title": "Effects of three-dimensional strain distribution on the performance of GaN-based light-emitting diodes on patterned sapphire substrates",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Shuo-Wei Chen",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Chia-Jui Chang",
                "org": ""
            },
            {
                "name": "Tien-Chang Lu",
                "org": ""
            }
        ],
        "venue": "Japanese Journal of Applied Physics",
        "year": 2019
    },
    "ojqAGDyS": {
        "id": "ojqAGDyS",
        "title": "Plasmonic Nanolasers Enhanced by Hybrid Graphene-Insulator-Metal Structures.",
        "abstract": "Graphene is a two-dimensional (2D) structure that creates linear relationship between energy and momentum that not only forms massless Dirac fermions with extremely high group velocity but also exhibits a broadband transmission from 300 to 2500 nm that can be applied to many optoelectronic applications, such as solar cells, light-emitting devices, touchscreens, ultrafast photodetectors, and lasers. Although the plasmonic resonance of graphene occurs in the terahertz band, graphene can be combined with a noble metal to provide a versatile platform for supporting surface plasmon waves. In this study, we propose a hybrid graphene-insulator-metal (GIM) structure that can modulate the surface plasmon polariton (SPP) dispersion characteristics and thus influence the performance of plasmonic nanolasers. Compared with values obtained when graphene is not used on an Al template, the propagation length of SPP waves can be increased to twice and the threshold of nanolasers is reduced by 50% when graphene is incorporated on the template. The GIM structure can be further applied in the future to realize electrical control or electrical injection of plasmonic devices through graphene.",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Jhu-Hong Li",
                "org": ""
            },
            {
                "name": "Kuo-Bin Hong",
                "org": ""
            },
            {
                "name": "Min-Wen Yu",
                "org": ""
            },
            {
                "name": "Yi-Cheng Chung",
                "org": ""
            },
            {
                "name": "Chu-Yuan Hsu",
                "org": ""
            },
            {
                "name": "Jhen-Hong Yang",
                "org": ""
            },
            {
                "name": "Chang-Wei Cheng",
                "org": ""
            },
            {
                "name": "Zhen-Ting Huang",
                "org": ""
            },
            {
                "name": "Kuo-Ping Chen",
                "org": ""
            },
            {
                "name": "Tzy-Rong Lin",
                "org": ""
            },
            {
                "name": "Shangjr Gwo",
                "org": ""
            },
            {
                "name": "Tien-Chang Lu",
                "org": ""
            }
        ],
        "venue": "Nano letters",
        "year": 2019
    },
    "c52ll89E": {
        "id": "c52ll89E",
        "title": "Nitrile-hydrolyzing enzyme from Meyerozyma guilliermondii and its potential in biosynthesis of 3-hydroxypropionic acid.",
        "abstract": "3-Hydroxypropionic acid (3-HP) is an important platform chemical in organic synthesis. Traditionally, 3-HP was produced by chemical methods and fermentation process. In this work, a novel enzymatic method was developed for green synthesis of 3-HP. A yeast strain harboring nitrile-hydrolyzing enzyme was newly isolated from environmental samples using 3-hydroxypropionitrile (3-HPN) as the sole nitrogen source. It was identified to be Meyerozyma guilliermondii CGMCC12935 by sequencing of the 18S ribosomal DNA and internal transcribed spacer, together with analysis of the morphology characteristics. The catalytic properties of M. guilliermondii CGMCC12935 resting cells were determined, and the optimum activity was achieved at 55\u2009\u00b0C and pH 7.5. The enzyme showed broad substrate specificity towards nitriles, especially 3-HPN, aminoacetonitrile and 3-cyanopyridine. The presence of Ag, Pb and excess substrate inhibited the enzyme activity, whereas 5% (v/v) ethyl acetate had a positive effect on the enzyme activity. M. guilliermondii CGMCC12935 resting cells by addition of 3% glucose could thoroughly hydrolyze 500\u00a0mM 3-HPN into 3-HP within 100\u00a0h and the maximal accumulative production of 3-HP reached 216.33\u00a0mM, which was over twofolds than the control group with no additional glucose. And this work would lay the foundation for biological production of 3-HP in industry.",
        "keywords": [
            "3-Hydroxypropionic acid",
            "3-Hydroxypropionitrile",
            "Meyerozyma guilliermondii",
            "Nitrile-hydrolyzing enzyme"
        ],
        "authors": [
            {
                "name": "Qiang Zhang",
                "org": "School of Pharmaceutical Science, Jiangnan University, Wuxi, 214122, People's Republic of China."
            },
            {
                "name": "Jin-Song Gong",
                "org": "School of Pharmaceutical Science, Jiangnan University, Wuxi, 214122, People's Republic of China."
            },
            {
                "name": "Ting-Ting Dong",
                "org": "School of Pharmaceutical Science, Jiangnan University, Wuxi, 214122, People's Republic of China."
            },
            {
                "name": "Ting-Ting Liu",
                "org": "School of Pharmaceutical Science, Jiangnan University, Wuxi, 214122, People's Republic of China."
            },
            {
                "name": "Heng Li",
                "org": "School of Pharmaceutical Science, Jiangnan University, Wuxi, 214122, People's Republic of China."
            },
            {
                "name": "Wen-Fang Dou",
                "org": "School of Pharmaceutical Science, Jiangnan University, Wuxi, 214122, People's Republic of China."
            },
            {
                "name": "Zhen-Ming Lu",
                "org": "National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi, 214122, People's Republic of China."
            },
            {
                "name": "Jin-Song Shi",
                "org": "School of Pharmaceutical Science, Jiangnan University, Wuxi, 214122, People's Republic of China."
            },
            {
                "name": "Zheng-Hong Xu",
                "org": "National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi, 214122, People's Republic of China. zhenghxu@jiangnan.edu.cn."
            }
        ],
        "venue": "Bioprocess and biosystems engineering",
        "year": 2017
    },
    "AZmuA0b0": {
        "id": "AZmuA0b0",
        "title": "Mining of a phospholipase D and its application in enzymatic preparation of phosphatidylserine.",
        "abstract": "Phosphatidylserine (PS) is useful as the additive in industries for memory improvement, mood enhancement and drug delivery. Conventionally, PS was extracted from soybeans, vegetable oils, egg yolk, and biomass; however, their low availability and high extraction cost were limiting factors. Phospholipase D (PLD) is a promising tool for enzymatic synthesis of PS due to its transphosphatidylation activity. In this contribution, a new and uncharacterized PLD was first obtained from GenBank database via genome mining strategy. The open reading frame consisted of 1614\u00a0bp and potentially encoded a protein of 538-amino-acid with a theoretical molecular mass of 60\u00a0kDa. The gene was successfully cloned and expressed in Escherichia coli. Its enzymatic properties were experimentally characterized. The temperature and pH optima of PLD were determined to be 60\u00b0C and 7.5, respectively. Its hydrolytic activity was improved by addition of Ca at 5\u00a0mM as compared with the control. The enzyme displayed suitable transphosphatidylation activity and PS could be synthesized with L-serine and soybean lecithin as substrates under the catalysis of PLD. This PLD enzyme might be a potential candidate for industrial applications in PS production. To the best of our knowledge, this is the first report on genome mining of PLDs from GenBank database.",
        "keywords": [
            "Cloning and expression",
            "Enzyme characterization",
            "Genome mining",
            "Phosphatidylserine",
            "Phospholipase D"
        ],
        "authors": [
            {
                "name": "Wen-Bin Zhou",
                "org": "a School of Pharmaceutical Science , Jiangnan University , Wuxi , PR China."
            },
            {
                "name": "Jin-Song Gong",
                "org": "a School of Pharmaceutical Science , Jiangnan University , Wuxi , PR China."
            },
            {
                "name": "Hai-Juan Hou",
                "org": "a School of Pharmaceutical Science , Jiangnan University , Wuxi , PR China."
            },
            {
                "name": "Heng Li",
                "org": "a School of Pharmaceutical Science , Jiangnan University , Wuxi , PR China."
            },
            {
                "name": "Zhen-Ming Lu",
                "org": "b National Engineering Laboratory for Cereal Fermentation Technology , Jiangnan University , Wuxi , PR China."
            },
            {
                "name": "Hong-Yu Xu",
                "org": "b National Engineering Laboratory for Cereal Fermentation Technology , Jiangnan University , Wuxi , PR China."
            },
            {
                "name": "Zheng-Hong Xu",
                "org": "b National Engineering Laboratory for Cereal Fermentation Technology , Jiangnan University , Wuxi , PR China."
            },
            {
                "name": "Jin-Song Shi",
                "org": "a School of Pharmaceutical Science , Jiangnan University , Wuxi , PR China."
            }
        ],
        "venue": "Bioengineered",
        "year": 2018
    },
    "4bKZMNxE": {
        "id": "4bKZMNxE",
        "title": "Efficient biocatalytic synthesis of nicotinic acid by recombinant nitrilase via high density culture.",
        "abstract": "The constitutively expression system for P. putida nitrilase was firstly constructed to improve the nicotinic acid production and reduce the production costs. High density culture strategy was employed to enhance the biomass and nitrilase production of recombinant strain. The total nitrilase activity reached up to 654\u202fU\u00b7mL without the induction. 541\u202fg\u00b7L nicotinic acid was accumulated via fed batch mode of substrate feeding through 290\u202fmin of conversion.",
        "keywords": [
            "Biocatalysis",
            "Fed-batch conversion",
            "High density culture",
            "Nicotinic acid",
            "Nitrilase"
        ],
        "authors": [
            {
                "name": "Jin-Song Gong",
                "org": "Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Pharmaceutical Sciences, Jiangnan University, Wuxi 214122, PR China."
            },
            {
                "name": "Qiang Zhang",
                "org": "Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Pharmaceutical Sciences, Jiangnan University, Wuxi 214122, PR China."
            },
            {
                "name": "Bing-Chen Gu",
                "org": "Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Pharmaceutical Sciences, Jiangnan University, Wuxi 214122, PR China."
            },
            {
                "name": "Ting-Ting Dong",
                "org": "Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Pharmaceutical Sciences, Jiangnan University, Wuxi 214122, PR China."
            },
            {
                "name": "Heng Li",
                "org": "Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Pharmaceutical Sciences, Jiangnan University, Wuxi 214122, PR China."
            },
            {
                "name": "Hui Li",
                "org": "Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Pharmaceutical Sciences, Jiangnan University, Wuxi 214122, PR China."
            },
            {
                "name": "Zhen-Ming Lu",
                "org": "Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Pharmaceutical Sciences, Jiangnan University, Wuxi 214122, PR China; National Engineering Laboratory for Cereal Fermentation Technology, School of Biotechnology, Jiangnan University, Wuxi 214122, PR China."
            },
            {
                "name": "Jin-Song Shi",
                "org": "Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Pharmaceutical Sciences, Jiangnan University, Wuxi 214122, PR China. Electronic address: shijs@163.com."
            },
            {
                "name": "Zheng-Hong Xu",
                "org": "Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Pharmaceutical Sciences, Jiangnan University, Wuxi 214122, PR China; National Engineering Laboratory for Cereal Fermentation Technology, School of Biotechnology, Jiangnan University, Wuxi 214122, PR China. Electronic address: zhenghxu@jiangnan.edu.cn."
            }
        ],
        "venue": "Bioresource technology",
        "year": 2018
    },
    "5pNfSCj4": {
        "id": "5pNfSCj4",
        "title": "Prebiotic mannan-oligosaccharides augment the hypoglycemic effects of metformin in correlation with modulating gut microbiota.",
        "abstract": "Type 2 diabetes (T2D) induced by obesity and high-fat diet is significantly associated with gut microbiota dysbacteriosis. Due to the first line clinical medicine of metformin has several intestinal drawbacks, combination usage of metformin with a prebiotic of konjac mannan-oligosaccharides (MOS) was conceived and implemented aiming to investigate whether there was some intestinal synergetic effects and how MOS would function. Composite treatment of metformin and MOS demonstrated synergistic effects on ameliorating insulin resistance and glucose tolerance, and repairing islet and hepatic histology. In addition, MF+MOS altered the gut community composition and structure by decreasing the relative abundances of family Rikenellaceae and order Clostridiales while increasing an unnamed OTU05945 of family S24-7, Akkermansia muciniphila, and Bifidobacterium pseudolongum. The present study suggested that usage of MOS could augment the hypoglycemic effects of metformin in association with gut microbiota modulation, which could provide references for further medication.",
        "keywords": "",
        "authors": [
            {
                "name": "Jialin Zheng",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Xiaojuan Zhang",
                "org": ""
            },
            {
                "name": "Min Jiang",
                "org": ""
            },
            {
                "name": "Chunqin Luo",
                "org": "Chengdu Yongan#R#Yuanhe Biotechnology Co. Ltd., Fifth Tianfu Street, Chengdu 611630, China"
            },
            {
                "name": "Zhenming Lu",
                "org": ""
            },
            {
                "name": "Zheng-Hong Xu",
                "org": ""
            },
            {
                "name": "Jin-Song Shi",
                "org": ""
            }
        ],
        "venue": "Journal of agricultural and food chemistry",
        "year": 2018
    },
    "m3EbcIGT": {
        "id": "m3EbcIGT",
        "title": "Depolymerized konjac glucomannan: preparation and application in health care.",
        "abstract": "Konjac glucomannan (KGM) is a water-soluble polysaccharide obtained from the roots and tubers of konjac plants. Recently, a degraded product of KGM, depolymerized KGM (DKGM), has attracted attention because of its low viscosity, improved hydrophily, and favorable physiological functions. In this review, we describe the preparation of DKGM and its prebiotic effects. Other health benefits of DKGM, covering antioxidant and immune activity, are also discussed, as well as its safety. DKGM could be a candidate for use as a tool for the treatment of various diseases, including intestinal flora imbalance, and oxidative- and immune-related disorders.",
        "keywords": [
            "Konjac glucomannan",
            "Depolymerized konjac glucomannan",
            "Prebiotics",
            "Immune response",
            "Antioxidant"
        ],
        "authors": [
            {
                "name": "Min Jiang",
                "org": "School of Pharmaceutical, Jiangnan University, Wuxi 214122, China."
            },
            {
                "name": "Heng Li",
                "org": "School of Pharmaceutical, Jiangnan University, Wuxi 214122, China."
            },
            {
                "name": "Jin-Song Shi",
                "org": "Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Pharmaceutical Science, Jiangnan University, Wuxi 214122, China."
            },
            {
                "name": "Zheng-Hong Xu",
                "org": "School of Biotechnology, Jiangnan University, Wuxi 214122, China."
            }
        ],
        "venue": "Journal of Zhejiang University. Science. B",
        "year": 2018
    },
    "AwpIILr0": {
        "id": "AwpIILr0",
        "title": "Purification and characterization of a high salt-tolerant alginate lyase from Cobetia sp. WG-007.",
        "abstract": "An alginate lyase producing bacterial strain, Cobetia sp. WG-007, was isolated and identified from rotting seaweed. The alginate lyase, Aly-W02, was purified by procedures of ultrafiltration, Q-Sepharose Fast Flow, Phenyl Sepharose 6 Fast Flow, and Superdex-G100 with specific activity of 21,285.5 U/mg. Aly-W02 had an apparent molecular mass of 35 kDa. It exhibited maximum activity at 45\u00a0\u00b0C in 50 mM sodium phosphate buffer (pH 8.5). This alginate lyase was stable in the pH range of 6.0-8.5. Among the tested metal ions, the addition of K , Na , and Mg ions can enhance the enzyme activities, while Ba , Ni , Cu , Mn , Zn , Ag , and ethylenediaminetetraacetic acid decreased the activities. It displayed high salt-tolerant ability; 0.8 M NaCl or 1.5 M KCl significantly enhanced the enzyme activity. Furthermore, Aly-W02 mainly released disaccharide, trisaccharide, and tetrasaccharid from alginate. It showed potential in producing low molecular weight alginate oligosaccharides.",
        "keywords": [
            "Cobetia sp",
            "alginate lyase",
            "characterization",
            "purification",
            "salt-tolerant"
        ],
        "authors": [
            {
                "name": "Jin-Song Gong",
                "org": "School of Pharmaceutical Science, Jiangnan University, Wuxi, Jiangsu Province, People's Republic of China."
            },
            {
                "name": "Xu-Mei Liu",
                "org": "School of Pharmaceutical Science, Jiangnan University, Wuxi, Jiangsu Province, People's Republic of China."
            },
            {
                "name": "Ming-Jie Zhang",
                "org": "School of Pharmaceutical Science, Jiangnan University, Wuxi, Jiangsu Province, People's Republic of China."
            },
            {
                "name": "Heng Li",
                "org": "School of Pharmaceutical Science, Jiangnan University, Wuxi, Jiangsu Province, People's Republic of China."
            },
            {
                "name": "Yan Geng",
                "org": "School of Pharmaceutical Science, Jiangnan University, Wuxi, Jiangsu Province, People's Republic of China."
            },
            {
                "name": "Hui Li",
                "org": "School of Pharmaceutical Science, Jiangnan University, Wuxi, Jiangsu Province, People's Republic of China."
            },
            {
                "name": "Jing Li",
                "org": "School of Pharmaceutical Science, Jiangnan University, Wuxi, Jiangsu Province, People's Republic of China."
            },
            {
                "name": "Zhen-Ming Lu",
                "org": "School of Pharmaceutical Science, Jiangnan University, Wuxi, Jiangsu Province, People's Republic of China."
            },
            {
                "name": "Zheng-Hong Xu",
                "org": "School of Pharmaceutical Science, Jiangnan University, Wuxi, Jiangsu Province, People's Republic of China."
            },
            {
                "name": "Jin-Song Shi",
                "org": "School of Pharmaceutical Science, Jiangnan University, Wuxi, Jiangsu Province, People's Republic of China."
            }
        ],
        "venue": "Biotechnology and applied biochemistry",
        "year": 2017
    },
    "DCj4c1kb": {
        "id": "DCj4c1kb",
        "title": "A novel alkaline surfactant-stable keratinase with superior feather-degrading potential based on library screening strategy.",
        "abstract": "A novel keratinase was mined and expressed in Escherichia coli BL21 (DE3) via function-driven screening with fosmid library. The catalytic properties of purified keratinase were investigated in detail following enzyme purification. The recombinant keratinase was purified to homogeneity with an estimated molecular weight of 26kDa using nickel affinity chromatography, of which the optimal reaction pH and temperature were 10.0 and 55\u00b0C, respectively. It could remain stable at pH 5.0-12.0 and 40-60\u00b0C. Metal ions such as Ca, Mn, Ag, Na, Mg, Li, Sn (1mM) displayed positive influence on keratinase, and particularly, Ca exhibited remarkable improvement effect by 2.6 folds. It was strongly inhibited by PMSF as a protease inhibitor. On the contrary, it could be obviously activated by various surfactants, such as Tween 40 and Triton X-114. The recombinant keratinase showed high specificity towards casein, soluble keratin, BSA, and wool. The keratinase could efficiently degrade the feathers, which demonstrated its applicable potential for biodegradation of keratin wastes and regeneration of soluble protein.",
        "keywords": [
            "Characterization",
            "Fosmid library",
            "Keratinase"
        ],
        "authors": [
            {
                "name": "Chang Su",
                "org": "School of Pharmaceutical Science, Jiangnan University, Wuxi 214122, PR China."
            },
            {
                "name": "Jin-Song Gong",
                "org": "School of Pharmaceutical Science, Jiangnan University, Wuxi 214122, PR China."
            },
            {
                "name": "Rong-Xian Zhang",
                "org": "School of Pharmaceutical Science, Jiangnan University, Wuxi 214122, PR China."
            },
            {
                "name": "Li-Yan Tao",
                "org": "School of Pharmaceutical Science, Jiangnan University, Wuxi 214122, PR China."
            },
            {
                "name": "Wen-Fang Dou",
                "org": "School of Pharmaceutical Science, Jiangnan University, Wuxi 214122, PR China."
            },
            {
                "name": "Dan-Dan Zhang",
                "org": "School of Pharmaceutical Science, Jiangnan University, Wuxi 214122, PR China."
            },
            {
                "name": "Heng Li",
                "org": "School of Pharmaceutical Science, Jiangnan University, Wuxi 214122, PR China."
            },
            {
                "name": "Zhen-Ming Lu",
                "org": "School of Pharmaceutical Science, Jiangnan University, Wuxi 214122, PR China."
            },
            {
                "name": "Zheng-Hong Xu",
                "org": "School of Pharmaceutical Science, Jiangnan University, Wuxi 214122, PR China."
            },
            {
                "name": "Jin-Song Shi",
                "org": "School of Pharmaceutical Science, Jiangnan University, Wuxi 214122, PR China. Electronic address: shijs@163.com."
            }
        ],
        "venue": "International journal of biological macromolecules",
        "year": 2017
    },
    "Nl73aMjo": {
        "id": "Nl73aMjo",
        "title": "Depolymerized konjac glucomannan: preparation and application in health care.",
        "abstract": "Konjac glucomannan (KGM) is a water-soluble polysaccharide obtained from the roots and tubers of konjac plants. Recently, a degraded product of KGM, depolymerized KGM (DKGM), has attracted attention because of its low viscosity, improved hydrophily, and favorable physiological functions. In this review, we describe the preparation of DKGM and its prebiotic effects. Other health benefits of DKGM, covering antioxidant and immune activity, are also discussed, as well as its safety. DKGM could be a candidate for use as a tool for the treatment of various diseases, including intestinal flora imbalance, and oxidative- and immune-related disorders.",
        "keywords": [
            "Konjac glucomannan",
            "Depolymerized konjac glucomannan",
            "Prebiotics",
            "Immune response",
            "Antioxidant"
        ],
        "authors": [
            {
                "name": "Min Jiang",
                "org": "School of Pharmaceutical, Jiangnan University, Wuxi 214122, China."
            },
            {
                "name": "Heng Li",
                "org": "School of Pharmaceutical, Jiangnan University, Wuxi 214122, China."
            },
            {
                "name": "Jin-Song Shi",
                "org": "Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Pharmaceutical Science, Jiangnan University, Wuxi 214122, China."
            },
            {
                "name": "Zheng-Hong Xu",
                "org": "School of Biotechnology, Jiangnan University, Wuxi 214122, China."
            }
        ],
        "venue": "Journal of Zhejiang University. Science. B",
        "year": 2018
    },
    "qslLVH5e": {
        "id": "qslLVH5e",
        "title": "Semi-rational engineering accelerates the laboratory evolution of nitrilase catalytic efficiency for nicotinic acid biosynthesis",
        "abstract": "The nitrilase-mediated green synthesis of nicotinic acid, an important reaction in synthetic organic chemistry, has attracted considerable attention in recent years. However, the application potential of nitrilase is hindered by several limitations, such as low catalytic efficiency and byproduct formation. In this study, the site saturation mutagenesis of asparagine 40, phenylalanine 50, and glutamine 207 in recombinant nitrilase from Pseudomonas putida CGMCC3830 was conducted to improve the specificity of nitrilase for nicotinic acid. The resulting mutants, which contain the mutations N40G (asparagine \u2192 glycine), F50W (phenylalanine \u2192 tryptophan), and Q207E (glutamine \u2192 glutamic acid) produced higher nicotinic acid yields than the wild type. Furthermore, double and triple mutations were introduced, and four mutants containing N40G/F50W, N40G/Q207E, F50W/Q207E, and N40G/F50W/Q207E were obtained and evaluated for their capacity to produce nicotinic acid. The double mutant F50W/Q207E and triple mutant N40G/F50W/Q207E displayed the highest activity, which was nearly two-fold higher than that of the wild type. The kinetics analysis of nicotinic acid synthesis with the mutant nitrilase revealed the higher catalytic capability of all the mutants compared with the wild type. These results provide new insights into the catalytic performance of P. putida nitrilase toward 3-cyanopyridine to promote nicotinic acid production.",
        "keywords": "",
        "authors": [
            {
                "name": "Jin-Song Gong",
                "org": "School of Pharmaceutical Science; Jiangnan University; Wuxi 214122 PR China"
            },
            {
                "name": "Ting-Ting Dong",
                "org": "School of Pharmaceutical Science; Jiangnan University; Wuxi 214122 PR China"
            },
            {
                "name": "Bing-Chen Gu",
                "org": "School of Pharmaceutical Science; Jiangnan University; Wuxi 214122 PR China"
            },
            {
                "name": "Heng Li",
                "org": "School of Pharmaceutical Science; Jiangnan University; Wuxi 214122 PR China"
            },
            {
                "name": "Wen-Fang Dou",
                "org": "School of Pharmaceutical Science; Jiangnan University; Wuxi 214122 PR China"
            },
            {
                "name": "Zhen-Ming Lu",
                "org": "School of Pharmaceutical Science; Jiangnan University; Wuxi 214122 PR China"
            },
            {
                "name": "Zhe-Min Zhou",
                "org": "The Key Laboratory of Industrial Biotechnology; Ministry of Education; Jiangnan University; Wuxi 214122 PR China"
            },
            {
                "name": "Jin-Song Shi",
                "org": "School of Pharmaceutical Science; Jiangnan University; Wuxi 214122 PR China"
            },
            {
                "name": "Zheng-Hong Xu",
                "org": "Jiangnan University, School of Pharmaceutical Science, Wuxi, CHINA"
            }
        ],
        "venue": "Chemcatchem",
        "year": 2017
    },
    "EvVLM5xn": {
        "id": "EvVLM5xn",
        "title": "Structural characterization and anti-alcoholic liver injury activity of a polysaccharide from Coriolus versicolor mycelia.",
        "abstract": "Polysaccharopeptide (PSP) from the medicinal mushroom Coriolus versicolor has been widely used in Asia as an adjunctive immunotherapy for treating cancers and liver diseases. However, the composition and structure of bioactive components in PSP remain elusive. Herein, we purified a hepatoprotective polysaccharide (PSP-1b1) with a molecular weight of 21.7\u202fkDa from C. versicolor mycelia in submerged culture. PSP-1b1 consists of fucose, galactose, xylose, mannose, glucuronic acid and glucose at a relative molar ratio of 0.16:0.60:0.02:0.55:0.04:1.00. Structural features were investigated by methylation and gas chromatography-mass spectrometry, Fourier transform infrared spectroscopy and nuclear magnetic resonance spectroscopy. The PSP-1b1 backbone consists of \u21924)-\u03b1-Galp-(1\u202f\u2192\u202f4)-\u03b1-Galp-(1\u202f\u2192\u202f2)-\u03b1-Manp-(1\u202f\u2192\u202f4)-\u03b1-Galp-(1\u202f\u2192\u202f2)-\u03b1-Manp-(1\u202f\u2192\u202f4)-\u03b1-Galp-(1\u202f\u2192\u202f4)-\u03b1-Galp-(1\u202f\u2192\u202f2)-\u03b1-Manp-(1\u202f\u2192\u202f4)-\u03b1-Galp-(1\u202f\u2192\u202f2)-\u03b1-Manp-(1\u202f\u2192\u202f4)\u2192, with branches of \u03b1-1,6-Manp, \u03b2-1,6-Glcp, \u03b2-1,3,6-Glcp, \u03b1-1,3-Manp, \u03b1-1,6-Galp, \u03b1-1,3-Fucp, T-\u03b1-Glcp and T-\u03b1-Galp on the O-6 position of \u03b1-Manp of the main chain, and secondary branches linked to the O-6 position of \u03b2-Glcp of the major branch. Treatment with PSK-1b1 (80 and 160\u202fmg/kg/day) resulted in hepatoprotective effects against alcohol-induced liver injury in mice by reducing oxidative stress and modulating immunity.",
        "keywords": [
            "Alcoholic liver injury",
            "Coriolus versicolor polysaccharide",
            "Purification and structure characterization"
        ],
        "authors": [
            {
                "name": "Kang-Le Wang",
                "org": "Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi 214122, China; School of Pharmaceutical Science, Jiangnan University, Wuxi 214122, PR China."
            },
            {
                "name": "Zhen-Ming Lu",
                "org": "National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi 214122, PR China; Jiangsu Engineering Research Center for Bioactive Products Processing Technology, Jiangnan University, Wuxi 214122, PR China. Electronic address: zmlu@jiangnan.edu.cn."
            },
            {
                "name": "Xiangjunzhi Mao",
                "org": "School of Pharmaceutical Science, Jiangnan University, Wuxi 214122, PR China."
            },
            {
                "name": "Lu Chen",
                "org": "School of Pharmaceutical Science, Jiangnan University, Wuxi 214122, PR China."
            },
            {
                "name": "Jin-Song Gong",
                "org": "School of Pharmaceutical Science, Jiangnan University, Wuxi 214122, PR China."
            },
            {
                "name": "Yi-Lin Ren",
                "org": "School of Pharmaceutical Science, Jiangnan University, Wuxi 214122, PR China."
            },
            {
                "name": "Yan Geng",
                "org": "School of Pharmaceutical Science, Jiangnan University, Wuxi 214122, PR China."
            },
            {
                "name": "Heng Li",
                "org": "Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi 214122, China; School of Pharmaceutical Science, Jiangnan University, Wuxi 214122, PR China."
            },
            {
                "name": "Hong-Yu Xu",
                "org": "National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi 214122, PR China; Jiangsu Engineering Research Center for Bioactive Products Processing Technology, Jiangnan University, Wuxi 214122, PR China."
            },
            {
                "name": "Guo-Hua Xu",
                "org": "Jiangsu Shenhua Pharmaceutical Co. Ltd, Huaian 211600, PR China."
            },
            {
                "name": "Jin-Song Shi",
                "org": "Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi 214122, China; School of Pharmaceutical Science, Jiangnan University, Wuxi 214122, PR China."
            },
            {
                "name": "Zheng-Hong Xu",
                "org": "Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi 214122, China; National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi 214122, PR China; Jiangsu Engineering Research Center for Bioactive Products Processing Technology, Jiangnan University, Wuxi 214122, PR China. Electronic address: zhenghxu@jiangnan.edu.cn."
            }
        ],
        "venue": "International journal of biological macromolecules",
        "year": 2019
    },
    "HZf5Hm2x": {
        "id": "HZf5Hm2x",
        "title": "Pd-Catalyzed double N-arylation of primary amines to synthesize phenoxazines and phenothiazines.",
        "abstract": "An efficient and versatile Pd-catalyzed tandem C-N bond formation between aryl halides and primary amines is developed. The transformation allows a one-pot synthesis of phenoxazine and phenothiazine derivatives with a broad range of substitution patterns from readily available precursors.",
        "keywords": "",
        "authors": [
            {
                "name": "Lu Zhang",
                "org": "College of Chemistry and Molecular Engineering, Zhengzhou University, Henan, China 450001. bx_yuan@163.com."
            },
            {
                "name": "Xin Huang",
                "org": "College of Chemistry and Molecular Engineering, Zhengzhou University,Henan,China 450001"
            },
            {
                "name": "Shan Zhen",
                "org": "College of Chemistry and Molecular Engineering, Zhengzhou University,Henan,China 450001"
            },
            {
                "name": "Jing Zhao",
                "org": "School of Pharmaceutical Sciences, Guangzhou Medical University,Guangdong,China 510182"
            },
            {
                "name": "Heng Li",
                "org": "College of Chemistry and Molecular Engineering, Zhengzhou University,Henan,China 450001"
            },
            {
                "name": "Bingxin Yuan",
                "org": "College of Chemistry and Molecular Engineering, Zhengzhou University,Henan,China 450001"
            },
            {
                "name": "Guanyu Yang",
                "org": "College of Chemistry and Molecular Engineering, Zhengzhou University,Henan,China 450001"
            }
        ],
        "venue": "Organic & biomolecular chemistry",
        "year": 2017
    },
    "nDkyBcLx": {
        "id": "nDkyBcLx",
        "title": "Cobalt-Catalyzed Aerobic Cross-dehydrogenative Coupling of C-H and Thiols in Water for C-S Formation.",
        "abstract": "Organosulfides have great significance and value in synthetic and biological chemistry. To establish a versatile and green methodology for C-S bond generation, we successfully developed a new aerobic cross-dehydrogenative coupling of C-H and S-H to synthesize arylsulfides in water, utilizing CoPcS as the catalyst and O2 as the oxidant. This protocol shows great tolerance of a wide range of substrates. A large variety of organosulfur compounds were produced in modest to excellent yields.",
        "keywords": "",
        "authors": [
            {
                "name": "Xin Huang",
                "org": ""
            },
            {
                "name": "Yongqi Chen",
                "org": ""
            },
            {
                "name": "Shan Zhen",
                "org": ""
            },
            {
                "name": "Lijuan Song",
                "org": ""
            },
            {
                "name": "Mingqi Gao",
                "org": ""
            },
            {
                "name": "Panke Zhang",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Bingxin Yuan",
                "org": ""
            },
            {
                "name": "Guanyu Yang",
                "org": ""
            }
        ],
        "venue": "The Journal of organic chemistry",
        "year": 2018
    },
    "qslkuASA": {
        "id": "qslkuASA",
        "title": "Scalable electrochemical oxidant-and metal-free dehydrogenative coupling of S-H/N-H.",
        "abstract": "A practical and scalable electrochemical oxidation of S-H and N-H was developed. This oxidant- and catalyst-free electrochemical process enables S-N bond formation with inexpensive nickel electrodes in an undivided cell. This procedure exhibits broad substrate scopes and good functional-group compatibility. A 50 g scale oxidative coupling augurs well for industrial applications.",
        "keywords": "",
        "authors": [
            {
                "name": "Shanyu Tang",
                "org": "Department of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, Henan, China 450001. hengli@zzu.edu.cn bxyuan@zzu.edu.cn."
            },
            {
                "name": "Yan Liu",
                "org": "School of Life Science, Zhengzhou University, Zhengzhou, Henan, China 450001."
            },
            {
                "name": "Longjia Li",
                "org": "Department of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, Henan, China 450001. hengli@zzu.edu.cn bxyuan@zzu.edu.cn."
            },
            {
                "name": "Xuanhe Ren",
                "org": "Department of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, Henan, China 450001. hengli@zzu.edu.cn bxyuan@zzu.edu.cn."
            },
            {
                "name": "Jiao Li",
                "org": "Department of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, Henan, China 450001. hengli@zzu.edu.cn bxyuan@zzu.edu.cn."
            },
            {
                "name": "Guanyu Yang",
                "org": "Department of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, Henan, China 450001. hengli@zzu.edu.cn bxyuan@zzu.edu.cn."
            },
            {
                "name": "Heng Li",
                "org": "Department of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, Henan, China 450001. hengli@zzu.edu.cn bxyuan@zzu.edu.cn."
            },
            {
                "name": "Bingxin Yuan",
                "org": "Department of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, Henan, China 450001. hengli@zzu.edu.cn bxyuan@zzu.edu.cn."
            }
        ],
        "venue": "Organic & biomolecular chemistry",
        "year": 2019
    },
    "Q0yH3M9l": {
        "id": "Q0yH3M9l",
        "title": "Palladium-catalyzed reductive Heck-type vinylative dearomatization of unfunctionalized halonaphthalene derivatives",
        "abstract": "A novel strategy for the dearomatization of inactive 1-halonaphthalenes via palladium-catalyzed reductive Heck-type vinylative reaction was successfully developed. Both homo- and hetero-cyclic naphthalene derivatives were tolerated, and the desired products were obtained in modest to good yields.",
        "keywords": "",
        "authors": [
            {
                "name": "Yingchao Dou",
                "org": "College of Chemistry and Molecular Engineering, Zhengzhou University,Zhengzhou,P. R. China"
            },
            {
                "name": "Liting Yang",
                "org": "College of Chemistry and Molecular Engineering, Zhengzhou University,Zhengzhou,P. R. China"
            },
            {
                "name": "Lu Zhang",
                "org": "College of Chemistry and Molecular Engineering, Zhengzhou University,Zhengzhou,P. R. China"
            },
            {
                "name": "Panke Zhang",
                "org": "College of Chemistry and Molecular Engineering, Zhengzhou University,Zhengzhou,P. R. China"
            },
            {
                "name": "Heng Li",
                "org": "College of Chemistry and Molecular Engineering, Zhengzhou University,Zhengzhou,P. R. China"
            },
            {
                "name": "Guanyu Yang",
                "org": "College of Chemistry and Molecular Engineering, Zhengzhou University,Zhengzhou,P. R. China"
            }
        ],
        "venue": "RSC Advances",
        "year": 2016
    },
    "BcdNzMVt": {
        "id": "BcdNzMVt",
        "title": "Rhodium-Catalyzed Borylation/Protonation Tandem Reaction of Hydroxylated Diarylethynes",
        "abstract": "The catalytic synthesis of trans-hydroxystilbenes has a great significance and value in synthetic chemistry and bioscience. To establish a versatile and efficient technology for such reactions, we successfully developed a novel and straightforward way for the construction of E-stilbene derivatives by a rhodium-catalyzed borylation/protonation tandem reaction using H2O as the green hydrogen source. Various E-stilbene derivatives were synthesized with up to 85\u2009% yield.",
        "keywords": "",
        "authors": [
            {
                "name": "Liting Yang",
                "org": "College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, Henan, China"
            },
            {
                "name": "Jinjin Ma",
                "org": "College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, Henan, China"
            },
            {
                "name": "Xiaomin Peng",
                "org": "College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, Henan, China"
            },
            {
                "name": "Danyang Wang",
                "org": "College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, Henan, China"
            },
            {
                "name": "Tao Guo",
                "org": "College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, Henan, China"
            },
            {
                "name": "Bingxin Yuan",
                "org": "College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, Henan, China"
            },
            {
                "name": "Heng Li",
                "org": "College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, Henan, China"
            },
            {
                "name": "Panke Zhang",
                "org": "College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, Henan, China"
            },
            {
                "name": "Guanyu Yang",
                "org": "College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, Henan, China"
            }
        ],
        "venue": "Asian Journal of Organic Chemistry",
        "year": 2017
    },
    "jof1MYan": {
        "id": "jof1MYan",
        "title": "TEMPO\u2010Catalyzed Aerobic Oxidative Coupling of Thiols for Metal\u2010Free Formation of S\u2212N/S\u2212S Bonds",
        "abstract": "The catalytic synthesis of organic sulfenamides and disulfides has great significance and value in synthetic chemistry and bioscience. To establish a versatile and efficient technology for such reactions, we successfully developed a new aerobic oxidative coupling method to construct S-N/S-S bonds, which uses TEMPO as the catalyst, and O2 as the oxidant. A variety of amines and thiols were well tolerated. Sulfenamides were produced in up to 99% yield while disulfides were formed in up to 97% yield in one-pot synthesis. The activation of N-H bond by 2,2-disbenzothiazoledisulfide showed the great potential in organic synthesis.",
        "keywords": "",
        "authors": [
            {
                "name": "Liting Yang",
                "org": "Zhengzhou University, College of Chemistry and Molecular Engineering, Zhengzhou, CHINA"
            },
            {
                "name": "Shuding Li",
                "org": "Zhengzhou University, College of Chemistry and Molecular Engineering, Zhengzhou, CHINA"
            },
            {
                "name": "Yingchao Dou",
                "org": "Zhengzhou University, College of Chemistry and Molecular Engineering, Zhengzhou, CHINA"
            },
            {
                "name": "Shan Zhen",
                "org": "Zhengzhou University, College of Chemistry and Molecular Engineering, Zhengzhou, CHINA"
            },
            {
                "name": "Heng Li",
                "org": "Zhengzhou University, College of Chemistry and Molecular Engineering, Zhengzhou, CHINA"
            },
            {
                "name": "Panke Zhang",
                "org": "Zhengzhou University, College of Chemistry and Molecular Engineering, Zhengzhou, CHINA"
            },
            {
                "name": "Bingxin Yuan",
                "org": "Zhengzhou University, College of Chemistry and Molecular Engineering, Zhengzhou, CHINA"
            },
            {
                "name": "Guanyu Yang",
                "org": "Zhengzhou University, College of Chemistry and Molecular Engineering, Zhengzhou, CHINA"
            }
        ],
        "venue": "Asian Journal of Organic Chemistry",
        "year": 2017
    },
    "88e6IzaO": {
        "id": "88e6IzaO",
        "title": "Reusable cobalt-phthalocyanine in water: efficient catalytic aerobic oxidative coupling of thiols to construct S\u2013N/S\u2013S bonds",
        "abstract": "A new aerobic oxidative coupling of thiols in water to construct sulfenamides or disulfides was developed, utilizing cobalt(II)phthalocyanine-tetra-sodium sulfonate as the catalyst and O2 as the oxidant. The mother liquor could be recycled up to 20 times with negligible loss of activity and only a minor decrease of product yield.",
        "keywords": "",
        "authors": [
            {
                "name": "Yingchao Dou",
                "org": "Department of Chemistry and Molecular Engineering, Zhengzhou University,Zhengzhou,China"
            },
            {
                "name": "Xin Huang",
                "org": "Department of Chemistry and Molecular Engineering, Zhengzhou University,Zhengzhou,China"
            },
            {
                "name": "Hao Wang",
                "org": "Department of Chemistry and Molecular Engineering, Zhengzhou University,Zhengzhou,China"
            },
            {
                "name": "Liting Yang",
                "org": "Department of Chemistry and Molecular Engineering, Zhengzhou University,Zhengzhou,China"
            },
            {
                "name": "Heng Li",
                "org": "Department of Chemistry and Molecular Engineering, Zhengzhou University,Zhengzhou,China"
            },
            {
                "name": "Bingxin Yuan",
                "org": "Department of Chemistry and Molecular Engineering, Zhengzhou University,Zhengzhou,China"
            },
            {
                "name": "Guanyu Yang",
                "org": "Department of Chemistry and Molecular Engineering, Zhengzhou University,Zhengzhou,China"
            }
        ],
        "venue": "Green Chemistry",
        "year": 2017
    },
    "y8mVhdNz": {
        "id": "y8mVhdNz",
        "title": "Co\u2010Catalyzed Intramolecular S\u2010N Bond Formation in Water for 1,2\u2010Benzisothiazol\u20103(2H)\u2010ones and 1,2,4\u2010Thiadiazoles Synthesis",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Liting Yang",
                "org": "College of Chemistry and Molecular Engineering Zhengzhou University 100 Kexue Avenue 450001 Zhengzhou P. R. China"
            },
            {
                "name": "Lijuan Song",
                "org": "College of Chemistry and Molecular Engineering Zhengzhou University 100 Kexue Avenue 450001 Zhengzhou P. R. China"
            },
            {
                "name": "Shanyu Tang",
                "org": "College of Chemistry and Molecular Engineering Zhengzhou University 100 Kexue Avenue 450001 Zhengzhou P. R. China"
            },
            {
                "name": "Longjia Li",
                "org": "College of Chemistry and Molecular Engineering Zhengzhou University 100 Kexue Avenue 450001 Zhengzhou P. R. China"
            },
            {
                "name": "Heng Li",
                "org": "College of Chemistry and Molecular Engineering Zhengzhou University 100 Kexue Avenue 450001 Zhengzhou P. R. China"
            },
            {
                "name": "Bingxin Yuan",
                "org": "College of Chemistry and Molecular Engineering Zhengzhou University 100 Kexue Avenue 450001 Zhengzhou P. R. China"
            },
            {
                "name": "Guanyu Yang",
                "org": "College of Chemistry and Molecular Engineering Zhengzhou University 100 Kexue Avenue 450001 Zhengzhou P. R. China"
            }
        ],
        "venue": "European Journal of Organic Chemistry",
        "year": 2019
    },
    "TWk2sHRz": {
        "id": "TWk2sHRz",
        "title": "Metallomicelle catalyzed aerobic tandem desilylation/Glaser reaction in water",
        "abstract": "PEG-grafted nitrogen ligands were synthesized. The corresponding copper complexes serve as metallomicellar nanoreactors for the aerobic tandem desilylation/Glaser coupling of TMS-protected alkynes in water. The protocol is also suitable for base-free homocoupling of terminal alkynes. The metallomicellar catalyst could be recycled 5 times with minor loss of reactivity.",
        "keywords": "",
        "authors": [
            {
                "name": "Shanyu Tang",
                "org": "College of Chemistry and Molecular Engineering, Zhengzhou University,,China"
            },
            {
                "name": "Longjia Li",
                "org": "College of Chemistry and Molecular Engineering, Zhengzhou University,,China"
            },
            {
                "name": "Xuanhe Ren",
                "org": "College of Chemistry and Molecular Engineering, Zhengzhou University,,China"
            },
            {
                "name": "Jiao Li",
                "org": "College of Chemistry and Molecular Engineering, Zhengzhou University,,China"
            },
            {
                "name": "Guanyu Yang",
                "org": "College of Chemistry and Molecular Engineering, Zhengzhou University,,China"
            },
            {
                "name": "Heng Li",
                "org": "College of Chemistry and Molecular Engineering, Zhengzhou University,,China"
            },
            {
                "name": "Bingxin Yuan",
                "org": "College of Chemistry and Molecular Engineering, Zhengzhou University,,China"
            }
        ],
        "venue": "Green Chemistry",
        "year": 2019
    },
    "FGAHEnjM": {
        "id": "FGAHEnjM",
        "title": "Amphiphilic ligands for Cu-catalyzed aerobic oxidation to synthesize 9-fluorenones in water",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Longjia Li",
                "org": ""
            },
            {
                "name": "Zibo Liu",
                "org": ""
            },
            {
                "name": "Shanyu Tang",
                "org": ""
            },
            {
                "name": "Jiao Li",
                "org": ""
            },
            {
                "name": "Xuanhe Ren",
                "org": ""
            },
            {
                "name": "Guanyu Yang",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Bingxin Yuan",
                "org": ""
            }
        ],
        "venue": "Catalysis Communications",
        "year": 2019
    },
    "FajMCdCo": {
        "id": "FajMCdCo",
        "title": "Surfactant-Type Catalyst for Aerobic Oxidative Coupling of Hydrazine with Thiol in Water.",
        "abstract": "A series of PEG-functionalized nitrogen ligands were developed to conduct an aerobic oxidative cross-coupling reaction between alkyl- or aryl-hydrazines with thiols in water. This surfactant-type catalyst enables high efficiencies and selectivities, while tolerating a large variety of functional groups. The mother liquor is still catalytically active after five runs.",
        "keywords": "",
        "authors": [
            {
                "name": "Xuanhe Ren",
                "org": "College of Chemistry and Molecular Engineering , Zhengzhou University , Henan 450001 , China."
            },
            {
                "name": "Shanyu Tang",
                "org": "College of Chemistry and Molecular Engineering , Zhengzhou University , Henan 450001 , China."
            },
            {
                "name": "Longjia Li",
                "org": "College of Chemistry and Molecular Engineering , Zhengzhou University , Henan 450001 , China."
            },
            {
                "name": "Jiao Li",
                "org": "College of Chemistry and Molecular Engineering , Zhengzhou University , Henan 450001 , China."
            },
            {
                "name": "Helong Liang",
                "org": "College of Chemistry and Molecular Engineering , Zhengzhou University , Henan 450001 , China."
            },
            {
                "name": "Ganzhong Li",
                "org": "College of Chemistry and Molecular Engineering , Zhengzhou University , Henan 450001 , China."
            },
            {
                "name": "Guanyu Yang",
                "org": "College of Chemistry and Molecular Engineering , Zhengzhou University , Henan 450001 , China."
            },
            {
                "name": "Heng Li",
                "org": "College of Chemistry and Molecular Engineering , Zhengzhou University , Henan 450001 , China."
            },
            {
                "name": "Bingxin Yuan",
                "org": "College of Chemistry and Molecular Engineering , Zhengzhou University , Henan 450001 , China."
            }
        ],
        "venue": "The Journal of organic chemistry",
        "year": 2019
    },
    "wyionLg7": {
        "id": "wyionLg7",
        "title": "Stochastic representation and dimension reduction for non-Gaussian random fields: review and reflection",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "heng li",
                "org": "peking university"
            },
            {
                "name": "dongxiao zhang",
                "org": "peking university"
            }
        ],
        "venue": "Stochastic Environmental Research and Risk Assessment",
        "year": 2013
    },
    "3q5cAAWw": {
        "id": "3q5cAAWw",
        "title": "Efficient data\u2010worth analysis for the selection of surveillance operation in a geologic CO2 sequestration system",
        "abstract": "",
        "keywords": [
            "uncertainty reduction",
            "co2 sequestration"
        ],
        "authors": [
            {
                "name": "cheng dai",
                "org": "peking university"
            },
            {
                "name": "heng li",
                "org": "peking university"
            },
            {
                "name": "dongxiao zhang",
                "org": "peking university"
            },
            {
                "name": "liang xue",
                "org": "china university of petroleum"
            }
        ],
        "venue": "",
        "year": 2015
    },
    "IUalcGNk": {
        "id": "IUalcGNk",
        "title": "Efficient and Accurate Quantification of Uncertainty for Multiphase Flow With the Probabilistic Collocation Method",
        "abstract": "",
        "keywords": [
            "collocation method",
            "uncertainty quantification",
            "monte carlo simulation"
        ],
        "authors": [
            {
                "name": "heng li",
                "org": "university of southern california"
            },
            {
                "name": "dongxiao zhang",
                "org": "university of southern california"
            }
        ],
        "venue": "Spe Journal",
        "year": 2009
    },
    "XSud1DUu": {
        "id": "XSud1DUu",
        "title": "A Comparative Study of the Probabilistic-Collocation and Experimental-Design Methods for Petroleum-Reservoir Uncertainty Quantification",
        "abstract": "",
        "keywords": [
            "orthogonal polynomials",
            "experimental design",
            "uncertainty quantification"
        ],
        "authors": [
            {
                "name": "heng li",
                "org": "university of southern california"
            },
            {
                "name": "pallav sarma",
                "org": "chevron corporation"
            },
            {
                "name": "dongxiao zhang",
                "org": "university of southern california"
            }
        ],
        "venue": "Spe Journal",
        "year": 2011
    },
    "bZQFX1bo": {
        "id": "bZQFX1bo",
        "title": "Probabilistic collocation method for flow in porous media: Comparisons with other stochastic methods: PROBABILISTIC COLLOCATION METHOD FOR FLOW IN POROUS MEDIA",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "heng li",
                "org": ""
            },
            {
                "name": "dongxiao zhang",
                "org": ""
            }
        ],
        "venue": "Water Resources Research",
        "year": 2007
    },
    "KvkmiG05": {
        "id": "KvkmiG05",
        "title": "Optical Properties of Heterojunction between Hybrid Halide Perovskite and Charge Transport Materials: Exciplex Emission and Large Polaron",
        "abstract": "The photoluminescence from exciplex states at lower energy than the bandgap of CH3NH3PbI3 (MAPbI3) was observed in both MAPbI3/Spiro-OMeTAD and MAPbI3/PCBM bilayer films. At the same time, using continuous wave photoinduced absorption (PIA) spectroscopy, we observed the PIA band at 0.14 eV, which was due to the positive or negative polarons in perovskite for MAPbI3/Spiro-OMeTAD and MAPbI3/PCBM film, respectively. The binding energies of both kinds of polarons are about \u223c40 meV, with the radius of phonon cloud of about 5.9 nm. Our finding may supply direct spectroscopic evidence for the existence of exciplex states in heterojunction of hybrid halide perovskite and charge transport materials as well as consequent large polarons in perovskite.",
        "keywords": "",
        "authors": [
            {
                "name": "Xiao Yang",
                "org": ""
            },
            {
                "name": "Yuchen Wang",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Chuanxiang Sheng",
                "org": ""
            }
        ],
        "venue": "Journal of Physical Chemistry C",
        "year": 2016
    },
    "X7tOwOpT": {
        "id": "X7tOwOpT",
        "title": "Photoluminescence in Organometal Halide Perovskites: Free Carrier Versus Exciton",
        "abstract": "The photoexcitation dynamics in CH 3 NH 3 PbI 3  thin films has been studied by nanosecond time-resolved photoluminescence (PL) and transient photoinduced absorption. Under excitation intensity from \u223c0.1 to \u223c100 \u03bcJ/cm 2 , free carrier is the dominant photoexcitation species. However, in the intermediate excitation intensity from \u223c1 to \u223c10 \u03bcJ/cm 2 , a small fraction of photoexcitations are excitons, which, however, are responsible for PL within this excitation intensity range. The branching ratio between excitons and free carriers at 2 \u03bcJ/cm 2  was estimated to be 17%. Furthermore, the spectral narrowing PL was found at the low temperature after the formation of excitons, indicating that laser action could be due to excitonic emission. Our findings provide fundamental insights into the optical properties of organometal halide perovskites with direct implications for optoelectronics.",
        "keywords": "",
        "authors": [
            {
                "name": "Xiao Yang",
                "org": "School of Electronic and Optical Engineering, Nanjing University of Science and Technology, Nanjing, China"
            },
            {
                "name": "Xiaoliang Yan",
                "org": "School of Electronic and Optical Engineering, Nanjing University of Science and Technology, Nanjing, China"
            },
            {
                "name": "Yuchen Wang",
                "org": "School of Electronic and Optical Engineering, Nanjing University of Science and Technology, Nanjing, China"
            },
            {
                "name": "Wei Chen",
                "org": "School of Electronic and Optical Engineering, Nanjing University of Science and Technology, Nanjing, China"
            },
            {
                "name": "Ruizhi Wang",
                "org": "School of Electronic and Optical Engineering, Nanjing University of Science and Technology, Nanjing, China"
            },
            {
                "name": "Weiwei Wang",
                "org": "School of Electronic and Optical Engineering, Nanjing University of Science and Technology, Nanjing, China"
            },
            {
                "name": "Heng Li",
                "org": "School of Electronic and Optical Engineering, Nanjing University of Science and Technology, Nanjing, China"
            },
            {
                "name": "Wanli Ma",
                "org": "Institute of Functional Nano and Soft Materials, Soochow University, Suzhou, China"
            },
            {
                "name": "Chuanxiang Sheng",
                "org": "School of Electronic and Optical Engineering, Nanjing University of Science and Technology, Nanjing, China"
            }
        ],
        "venue": "IEEE Journal of Photovoltaics",
        "year": 2017
    },
    "0I5Mm0Qs": {
        "id": "0I5Mm0Qs",
        "title": "Effect on the morphology and optical properties of CH3NH3PbI3 with additive of NH4Cl",
        "abstract": "Abstract   Rapid emergence of solar cells based on mixed organic-inorganic halide perovskite have led to high power conversion efficiencies of over 20% in recent years. Looking for a simple and convenient way to fine-control of the perovskite film morphology is becoming one of the main issues. In this work, we explore the effect of adding NH 4 Cl on crystallization process and optical properties of perovskite. With adding NH 4 Cl, the perovskite films prepared by one-step method present better morphology than films without adding NH 4 Cl, namely, smoother surface and better coverage which result in uniform and much more stable photoluminescence intensities as well as longer lifetime of photoexcitations. More importantly, the photovoltaic cells fabricated with the addition of the NH 4 Cl have far better performance than the cells without additives. Therefore, one-step fabrication method can also control the morphology of perovskite films finely for both optical application and solar cells with adding proper additive.",
        "keywords": "",
        "authors": [
            {
                "name": "Xiaoliang Yan",
                "org": "School of Electronic and Optical Engineering, Nanjing University of Science and Technology, Nanjing, 210094, PR China"
            },
            {
                "name": "Xiao Yang",
                "org": "School of Electronic and Optical Engineering, Nanjing University of Science and Technology, Nanjing, 210094, PR China"
            },
            {
                "name": "Ruizhi Wang",
                "org": "School of Electronic and Optical Engineering, Nanjing University of Science and Technology, Nanjing, 210094, PR China"
            },
            {
                "name": "Heng Li",
                "org": "School of Electronic and Optical Engineering, Nanjing University of Science and Technology, Nanjing, 210094, PR China"
            },
            {
                "name": "Chuanxiang Sheng",
                "org": "School of Electronic and Optical Engineering, Nanjing University of Science and Technology, Nanjing, 210094, PR China"
            }
        ],
        "venue": "Optical Materials",
        "year": 2017
    },
    "RREWf8HR": {
        "id": "RREWf8HR",
        "title": "Origin of thermal instability of CH3NH3PbI3\u2212xClx films for photovoltaic devices",
        "abstract": "Abstract   The rapid improvements in perovskite solar cells have led to high power conversion efficiencies of over 20% in recent years. Despite this remarkable performance, the mechanism of thermal instability for those films is still one of the problems that we have to face. In this work, we systematically measure the thermal stability of CH 3 NH 3 PbI 3\u2212x Cl x  films on substrates of ITO, PEDOT:PSS/ITO, TiO 2 /ITO, at various temperatures. Comparing their counterparts on Glass, PEDOT:PSS/Glass, TiO 2 /Glass, we found that the films on substrates with ITO are always less thermal stable, resulting from charge transfer between perovskite and ITO substrates, in particular at higher annealing temperatures. Therefore, it was believed that more thermal degradation can occur in CH 3 NH 3 PbI 3\u2212x Cl x  film with less neutral electrical environment.",
        "keywords": "",
        "authors": [
            {
                "name": "Xiaoliang Yan",
                "org": "School of Electronic and Optical Engineering, Nanjing University of Science and Technology, Nanjing 210094, PR China"
            },
            {
                "name": "Wei Wang",
                "org": "School of Electronic and Optical Engineering, Nanjing University of Science and Technology, Nanjing 210094, PR China"
            },
            {
                "name": "Xiao Yang",
                "org": "School of Electronic and Optical Engineering, Nanjing University of Science and Technology, Nanjing 210094, PR China"
            },
            {
                "name": "Wuming Yi",
                "org": "School of Electronic and Optical Engineering, Nanjing University of Science and Technology, Nanjing 210094, PR China"
            },
            {
                "name": "Yuning Wang",
                "org": "School of Electronic and Optical Engineering, Nanjing University of Science and Technology, Nanjing 210094, PR China"
            },
            {
                "name": "Heng Li",
                "org": "School of Electronic and Optical Engineering, Nanjing University of Science and Technology, Nanjing 210094, PR China"
            },
            {
                "name": "Wenhua Gu",
                "org": "School of Electronic and Optical Engineering, Nanjing University of Science and Technology, Nanjing 210094, PR China"
            },
            {
                "name": "ChuanXiang Sheng",
                "org": "School of Electronic and Optical Engineering, Nanjing University of Science and Technology, Nanjing 210094, PR China"
            }
        ],
        "venue": "Materials Letters",
        "year": 2016
    },
    "4yZ0UKga": {
        "id": "4yZ0UKga",
        "title": "Light induced metastable modification of optical properties in CH3NH3PbI3\u2212xBrx perovskite films: Two-step mechanism",
        "abstract": "Abstract   We have used photoluminescence (PL) and photomodulation (PM) spectroscopy to investigate the reversible spectral changes of PL in CH 3 NH 3 PbI 3\u2212x Br x  films, where x is 1.7. In an as-prepared film, the peak of PL spectra shifts from \u223c640\u00a0nm near bandedge to \u223c750\u00a0nm after excitation by a continuous wave (CW) or a pulsed laser with high repetition rate, but keeps at 640\u00a0nm excited by same pulsed laser with the repetition rate smaller than 500\u00a0Hz. The PM spectroscopy also shows the formation of sub bandgap states after illumination which is responsible for the red shift of PL. The light induced modification of optical properties is reversible after keeping the film out of illumination for several hours at room temperature. We analyze the photoinduced modification to be two-steps processes: the temporary sub bandgap states were first photogenerated in perovskite film, if those states interacting with more coming photons within their lifetimes, light induced metastable states responsible for red-shift of PL will be formed. This instability reduces the electronic bandgap and generates more traps which will degrade the performance of the related photovoltaic devices.",
        "keywords": "",
        "authors": [
            {
                "name": "Xiao Yang",
                "org": "School of Electronic and Optical Engineering, Nanjing University of Science and Technology, Nanjing 210094, China"
            },
            {
                "name": "Xiaoliang Yan",
                "org": "School of Electronic and Optical Engineering, Nanjing University of Science and Technology, Nanjing 210094, China"
            },
            {
                "name": "Wei Wang",
                "org": "School of Electronic and Optical Engineering, Nanjing University of Science and Technology, Nanjing 210094, China"
            },
            {
                "name": "Xiangxiang Zhu",
                "org": "Institute of Functional Nano & Soft Materials (FUNSOM) & Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University, Suzhou 215123, China"
            },
            {
                "name": "Heng Li",
                "org": "School of Electronic and Optical Engineering, Nanjing University of Science and Technology, Nanjing 210094, China"
            },
            {
                "name": "Wanli Ma",
                "org": "Institute of Functional Nano & Soft Materials (FUNSOM) & Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University, Suzhou 215123, China"
            },
            {
                "name": "ChuanXiang Sheng",
                "org": "School of Electronic and Optical Engineering, Nanjing University of Science and Technology, Nanjing 210094, China"
            }
        ],
        "venue": "Organic Electronics",
        "year": 2016
    },
    "FTPzOCJz": {
        "id": "FTPzOCJz",
        "title": "Circularly polarized photoluminescence and Hanle effect measurements of spin relaxation in organic\u2013inorganic hybrid perovskite films",
        "abstract": "Partial circularly polarized photoluminescence (CPL) with a polarization degree (P) of 2% from CH3NH3PbBr3 film at 77 K is observed, excited by a circularly polarized 532 nm laser. However, P decreases to 0.3% when excited using a circularly polarized 447 nm laser, and to zero using a linear polarized laser. The Hanle effect is measured to study spin relaxation in CH3NH3PbBr3 film, yielding a spin lifetime of \u223c240 ps at 77 K, which however becomes one order of magnitude smaller when the temperature increases to 110 K. The existence of a CPL that is dependent on the helicity of the excitation laser, and the unexpectedly long spin lifetime with large spin\u2013orbit coupling, suggest the potential of hybrid perovskites for spintronic applications.",
        "keywords": "",
        "authors": [
            {
                "name": "Ruizhi Wang",
                "org": "School of Electronic and Optical Engineering, Nanjing University of Science and Technology,Nanjing 210094,China"
            },
            {
                "name": "Shu Hu",
                "org": "School of Electronic and Optical Engineering, Nanjing University of Science and Technology,Nanjing 210094,China"
            },
            {
                "name": "Xiao Yang",
                "org": "School of Electronic and Optical Engineering, Nanjing University of Science and Technology,Nanjing 210094,China"
            },
            {
                "name": "Xiaoliang Yan",
                "org": "School of Electronic and Optical Engineering, Nanjing University of Science and Technology,Nanjing 210094,China"
            },
            {
                "name": "Heng Li",
                "org": "School of Electronic and Optical Engineering, Nanjing University of Science and Technology,Nanjing 210094,China"
            },
            {
                "name": "ChuanXiang Sheng",
                "org": "School of Electronic and Optical Engineering, Nanjing University of Science and Technology,Nanjing 210094,China"
            }
        ],
        "venue": "Journal of Materials Chemistry C",
        "year": 2018
    },
    "WP9XdcRV": {
        "id": "WP9XdcRV",
        "title": "Evanescent-wave pumped single-mode microcavity laser from fiber of 125 \u03bcm diameter",
        "abstract": "A microcavity laser based on evanescent-wave-coupled gain is formed using a silica fiber with a diameter of 125\u00a0\u03bcm in a rhodamine 6G ethanol solution. When the fiber is sticking to the cuvette wall by capillary force, using the excitation of a 532\u00a0nm nanosecond pulsed laser, single-mode laser emission is observed. While increasing the distance between the fiber and the cuvette wall, the typical multi-peak whispering-gallery-mode (WGM) laser emission can also be demonstrated. On the other hand, while increasing the refractive index of the solution by mixing ethanol and ethylene glycol with different ratios as a solvent, the single-mode emission would evolve to multi-peak WGM laser emission controllably.",
        "keywords": "",
        "authors": [
            {
                "name": "Yuchen Wang",
                "org": "School of Electronic and Optical Engineering, Nanjing University of Science and Technology, Nanjing 210094, China"
            },
            {
                "name": "Shu Hu",
                "org": "School of Electronic and Optical Engineering, Nanjing University of Science and Technology, Nanjing 210094, China"
            },
            {
                "name": "Xiao Yang",
                "org": "Faculty of Electronic Information Engineering, Huaiyin Institute of Technology, Huaian 223003, China"
            },
            {
                "name": "Ruizhi Wang",
                "org": "School of Electronic and Optical Engineering, Nanjing University of Science and Technology, Nanjing 210094, China"
            },
            {
                "name": "Heng Li",
                "org": "School of Electronic and Optical Engineering, Nanjing University of Science and Technology, Nanjing 210094, China"
            },
            {
                "name": "Chuanxiang Sheng",
                "org": "School of Electronic and Optical Engineering, Nanjing University of Science and Technology, Nanjing 210094, China"
            }
        ],
        "venue": "Photonics Research",
        "year": 2018
    },
    "tWxrqzEO": {
        "id": "tWxrqzEO",
        "title": "Magnetic field-assisted formation of charge transfer complex in \u03c0-conjugated polymer and fullerene-blended films",
        "abstract": "Blended films of poly [2-methoxy-5-(2-ethylhexyloxy)-1, 4-phenylenevinylene] (MEH-PPV)/[6, 6]-phenyl-C61-butyric acid methyl ester (PCBM) were annealed at 70\u00b0C under rotational magnetic field (RMF) (\u223c350\u2009\u2009G with 600 RPM) for 10 min. At low temperatures, the films prepared with RMF contained new spectral features. The photoluminescence (PL) spectra of films prepared under RMF had two peaks (1.59 and 1.73 eV), whereas films prepared without RMF had a single PL band at 1.75 eV. Furthermore, the photoinduced absorption (PIA) spectra of films prepared with RMF showed an additional PIA band at 1.15 eV, along with the well-known PIA band at 1.35 eV due to excited state absorption by polarons. We conclude that the spectral features in MEH-PPV/PCBM films were due to charge transfer complexes (CTC), the formation of which is promoted by RMF. Our results suggested that applying proper magnetic field while preparing polymer/fullerene film could improve the formation of CTC. We discuss the relevance to solar cell applications.",
        "keywords": "",
        "authors": [
            {
                "name": "Shu Hu",
                "org": "Nanjing Univ. of Science and Technology (China)"
            },
            {
                "name": "Ruizhi Wang",
                "org": "Nanjing Univ. of Science and Technology (China)"
            },
            {
                "name": "Xiao Yang",
                "org": "Nanjing Univ. of Science and Technology (China)"
            },
            {
                "name": "Yuchen Wang",
                "org": "Nanjing Univ. of Science and Technology (China)"
            },
            {
                "name": "Yuchen Wang",
                "org": "Nanjing Univ. of Science and Technology (China)"
            },
            {
                "name": "Xiaoliang Yan",
                "org": "Nanjing Univ. of Science and Technology (China)"
            },
            {
                "name": "Yang Zhang",
                "org": "Nanjing Univ. of Science and Technology (China)"
            },
            {
                "name": "Heng Li",
                "org": "Nanjing Univ. of Science and Technology (China)"
            },
            {
                "name": "ChuanXiang Sheng",
                "org": "Nanjing Univ. of Science and Technology (China)"
            }
        ],
        "venue": "Journal of Photonics for Energy",
        "year": 2018
    },
    "2Zr7fnc7": {
        "id": "2Zr7fnc7",
        "title": "ChemInform Abstract: Alkaline Earth Metallocenes Coordinated with Ester Pendants: Synthesis, Structural Characterization, and Application in Metathesis Reactions.",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "heng li",
                "org": "science college"
            },
            {
                "name": "wenxiong zhang",
                "org": "science college"
            },
            {
                "name": "zhenfeng xi",
                "org": "science college"
            }
        ],
        "venue": "Cheminform",
        "year": 2014
    },
    "VkFEJIe1": {
        "id": "VkFEJIe1",
        "title": "ChemInform Abstract: Iterative Dianion Relay Along the Ring: Formation of gem\u2010Bis(trimethylsilyl) Cyclopentenones from 2,5\u2010Bis(trimethylsilyl) Oxycyclopentadienyl Dianions and Acid Chlorides.",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "heng li",
                "org": "science college"
            },
            {
                "name": "lantao liu",
                "org": "science college"
            },
            {
                "name": "zitao wang",
                "org": "science college"
            },
            {
                "name": "fei zhao",
                "org": "science college"
            },
            {
                "name": "shaoguang zhang",
                "org": "science college"
            },
            {
                "name": "wenxiong zhang",
                "org": "science college"
            },
            {
                "name": "zhenfeng xi",
                "org": "science college"
            }
        ],
        "venue": "Cheminform",
        "year": 2011
    },
    "IOJiM7Na": {
        "id": "IOJiM7Na",
        "title": "Innenr\u00fccktitelbild: Barium Dibenzopentalenide as a Main\u2010Group Metal \u03b78 Complex: Facile Synthesis from 1,4\u2010Dilithio\u20101,3\u2010butadienes and Ba[N(SiMe3)2]2, Structural Characterization, and Reaction Chemistry (Angew. Chem. 41/2013)",
        "abstract": "",
        "keywords": [
            "barium"
        ],
        "authors": [
            {
                "name": "heng li",
                "org": "uc berkeley college of chemistry"
            },
            {
                "name": "baosheng wei",
                "org": "uc berkeley college of chemistry"
            },
            {
                "name": "ling xu",
                "org": "uc berkeley college of chemistry"
            },
            {
                "name": "wenxiong zhang",
                "org": "uc berkeley college of chemistry"
            },
            {
                "name": "zhenfeng xi",
                "org": "uc berkeley college of chemistry"
            }
        ],
        "venue": "Angewandte Chemie",
        "year": 2013
    },
    "qxpqlpX3": {
        "id": "qxpqlpX3",
        "title": "Inside Back Cover: Barium Dibenzopentalenide as a Main\u2010Group Metal \u03b78 Complex: Facile Synthesis from 1,4\u2010Dilithio\u20101,3\u2010butadienes and Ba[N(SiMe3)2]2, Structural Characterization, and Reaction Chemistry (Angew. Chem. Int. Ed. 41/2013)",
        "abstract": "",
        "keywords": [
            "barium"
        ],
        "authors": [
            {
                "name": "heng li",
                "org": "uc berkeley college of chemistry"
            },
            {
                "name": "baosheng wei",
                "org": "uc berkeley college of chemistry"
            },
            {
                "name": "ling xu",
                "org": "uc berkeley college of chemistry"
            },
            {
                "name": "wenxiong zhang",
                "org": "uc berkeley college of chemistry"
            },
            {
                "name": "zhenfeng xi",
                "org": "uc berkeley college of chemistry"
            }
        ],
        "venue": "Angewandte Chemie",
        "year": 2013
    },
    "ulmFT3tH": {
        "id": "ulmFT3tH",
        "title": "Barium Dibenzopentalenide as a Main\u2010Group Metal \u03b78 Complex: Facile Synthesis from 1,4\u2010Dilithio\u20101,3\u2010butadienes and Ba[N(SiMe3)2]2, Structural Characterization, and Reaction Chemistry",
        "abstract": "",
        "keywords": [
            "barium"
        ],
        "authors": [
            {
                "name": "heng li",
                "org": "uc berkeley college of chemistry"
            },
            {
                "name": "baosheng wei",
                "org": "uc berkeley college of chemistry"
            },
            {
                "name": "ling xu",
                "org": "uc berkeley college of chemistry"
            },
            {
                "name": "wenxiong zhang",
                "org": "uc berkeley college of chemistry"
            },
            {
                "name": "zhenfeng xi",
                "org": "uc berkeley college of chemistry"
            }
        ],
        "venue": "Angewandte Chemie",
        "year": 2013
    },
    "wuqKhQSU": {
        "id": "wuqKhQSU",
        "title": "Calcium-Mediated C\u2013H and C\u2013F Bond Cleavage: Synthesis of Indenes and Perfluorodibenzopentalenes from 1,4-Dilithio-1,3-butadienes",
        "abstract": "The development of Ca-mediated reactions is of great importance and is in great demand in both organometallic and organic chemistry. In this paper, we report that calcium iodide efficiently promotes the transformation of various 1,4-dilithio-1,3-butadienes into indenes or perfluorodibenzopentalenes, via an intramolecular C\u2013H or C\u2013F bond cleavage, respectively. In the reaction process, the Ca-induced s-cis/trans configurational isomerization of 1,4-dilithio-1,3-butadienes is followed by the subsequent nucleophilic C\u2013H or C\u2013F bond activation.",
        "keywords": "",
        "authors": [
            {
                "name": "Baosheng Wei",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Wen-Xiong Zhang",
                "org": ""
            },
            {
                "name": "Zhenfeng Xi",
                "org": ""
            }
        ],
        "venue": "Organometallics",
        "year": 2016
    },
    "Va2BKnKG": {
        "id": "Va2BKnKG",
        "title": "Spot-Scanning Proton Therapy Patient-Specific Quality Assurance: Results from 309 Treatment Plans",
        "abstract": "",
        "keywords": [
            "quality assurance"
        ],
        "authors": [
            {
                "name": "d mackin",
                "org": ""
            },
            {
                "name": "x ronald zhu",
                "org": ""
            },
            {
                "name": "falk poenisch",
                "org": ""
            },
            {
                "name": "heng li",
                "org": ""
            },
            {
                "name": "narayan sahoo",
                "org": ""
            },
            {
                "name": "m kerr",
                "org": ""
            },
            {
                "name": "charles holmes",
                "org": ""
            },
            {
                "name": "yupeng li",
                "org": ""
            },
            {
                "name": "m lii",
                "org": ""
            },
            {
                "name": "richard wu",
                "org": ""
            },
            {
                "name": "kazumichi suzuki",
                "org": ""
            },
            {
                "name": "michael t gillin",
                "org": ""
            },
            {
                "name": "steven j frank",
                "org": ""
            },
            {
                "name": "david r grosshans",
                "org": ""
            },
            {
                "name": "xiaodong zhang",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2014
    },
    "AKVFE5Iq": {
        "id": "AKVFE5Iq",
        "title": "Erratum: \u201cDynamically accumulated dose and 4D accumulated dose for moving tumors\u201d [Med. Phys.39(12), 7359\u20137367 (2012)]",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "heng li",
                "org": ""
            },
            {
                "name": "yupeng li",
                "org": ""
            },
            {
                "name": "xiaodong zhang",
                "org": ""
            },
            {
                "name": "xiaoqiang li",
                "org": ""
            },
            {
                "name": "wei liu",
                "org": ""
            },
            {
                "name": "michael t gillin",
                "org": ""
            },
            {
                "name": "x ronald zhu",
                "org": ""
            }
        ],
        "venue": "Medical Physics",
        "year": 2013
    },
    "1QoIXDMR": {
        "id": "1QoIXDMR",
        "title": "Selective robust optimization",
        "abstract": "",
        "keywords": [
            "ptv",
            "robust optimization"
        ],
        "authors": [
            {
                "name": "yupeng li",
                "org": ""
            },
            {
                "name": "perttu niemela",
                "org": ""
            },
            {
                "name": "li liao",
                "org": ""
            },
            {
                "name": "shengpeng jiang",
                "org": ""
            },
            {
                "name": "heng li",
                "org": ""
            },
            {
                "name": "falk poenisch",
                "org": ""
            },
            {
                "name": "x r zhu",
                "org": ""
            },
            {
                "name": "sami siljamaki",
                "org": ""
            },
            {
                "name": "reynald vanderstraeten",
                "org": ""
            },
            {
                "name": "narayan sahoo",
                "org": ""
            },
            {
                "name": "michael t gillin",
                "org": ""
            },
            {
                "name": "xiaodong zhang",
                "org": ""
            }
        ],
        "venue": "Medical Physics",
        "year": 2015
    },
    "eC006tuB": {
        "id": "eC006tuB",
        "title": "Selective robust optimization: A new intensity-modulated proton therapy optimization strategy.",
        "abstract": "Selective robust optimization may provide the flexibility and capability necessary for meeting various clinical requirements in addition to achieving the required plan robustness in practical proton treatment planning settings.",
        "keywords": [],
        "authors": [
            {
                "name": "yupeng li",
                "org": ""
            },
            {
                "name": "perttu niemela",
                "org": ""
            },
            {
                "name": "li liao",
                "org": ""
            },
            {
                "name": "shengpeng jiang",
                "org": ""
            },
            {
                "name": "heng li",
                "org": ""
            },
            {
                "name": "falk poenisch",
                "org": ""
            },
            {
                "name": "x ronald zhu",
                "org": ""
            },
            {
                "name": "sami siljamaki",
                "org": ""
            },
            {
                "name": "reynald vanderstraeten",
                "org": ""
            },
            {
                "name": "narayan sahoo",
                "org": ""
            },
            {
                "name": "michael t gillin",
                "org": ""
            },
            {
                "name": "xiaodong zhang",
                "org": ""
            }
        ],
        "venue": "Medical physics",
        "year": 2015
    },
    "BGWBd0N2": {
        "id": "BGWBd0N2",
        "title": "SU\u2010D\u2010BRCD\u201001: Evaluation of Zebra Multi\u2010Layer Ionization Chamber System for Patient Treatment Field and Machine QA for Spot Scanning and Passive Scattering Proton Beams",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "s dhanesar",
                "org": ""
            },
            {
                "name": "n sahoo",
                "org": ""
            },
            {
                "name": "michael d taylor",
                "org": ""
            },
            {
                "name": "xiaofei song",
                "org": ""
            },
            {
                "name": "falk poenisch",
                "org": ""
            },
            {
                "name": "paul summers",
                "org": ""
            },
            {
                "name": "heng li",
                "org": ""
            },
            {
                "name": "x r zhu",
                "org": ""
            },
            {
                "name": "michael t gillin",
                "org": ""
            }
        ],
        "venue": "Medical Physics",
        "year": 2012
    },
    "0GzWz3O4": {
        "id": "0GzWz3O4",
        "title": "3D treatment planning system\u2014Varian Eclipse for proton therapy planning",
        "abstract": "Abstract   The capabilities of the Eclipse treatment planning system (TPS) (Varian Medical Systems, Palo Alto, CA) for proton therapy treatment planning are described. Various steps involved in the planning process to produce a 3-dimensional (3D) dose distribution both for the passive scattering and pencil beam scanning proton beam therapy are outlined. Mitigation of range and setup uncertainties through robust optimization is discussed. Use of verification plans for patient treatment field dosimetry quality assurance (QA) is presented. Limitations of the Eclipse TPS and future developments are discussed.",
        "keywords": "",
        "authors": [
            {
                "name": "Narayan Sahoo",
                "org": "Radiation Physics"
            },
            {
                "name": "Falk Poenisch",
                "org": "Radiation Physics"
            },
            {
                "name": "Xiaodong Zhang",
                "org": "Department of Radiation Physics, UT M.D. Anderson Cancer Center, Houston, TX"
            },
            {
                "name": "Yupeng Li",
                "org": "Department of Radiation Physics, UT M.D. Anderson Cancer Center, Houston, TX"
            },
            {
                "name": "Ming Fu Lii",
                "org": "Department of Radiation Physics, UT M.D. Anderson Cancer Center, Houston, TX"
            },
            {
                "name": "Heng Li",
                "org": "Department of Radiation Physics, UT M.D. Anderson Cancer Center, Houston, TX"
            },
            {
                "name": "Archana S. Gautam",
                "org": "Department of Radiation Physics, UT M.D. Anderson Cancer Center, Houston, TX"
            },
            {
                "name": "Richard Wu",
                "org": "Department of Radiation Physics, UT M.D. Anderson Cancer Center, Houston, TX"
            },
            {
                "name": "Michael Gillin",
                "org": "Radiation Physics"
            },
            {
                "name": "Xiaorong Ronald Zhu",
                "org": "Radiation Physics"
            }
        ],
        "venue": "Medical Dosimetry",
        "year": 2018
    },
    "hXWp569L": {
        "id": "hXWp569L",
        "title": "Statins reduce the expressions of Tim-3 on NK cells and NKT cells in atherosclerosis.",
        "abstract": "3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase inhibitors (statins) have an immuno-regulatory effect in addition to lowing-lipids. Accumulated evidences showed that the expressions of T cell immunoglobulin- and mucin-domain-containing molecule-3(Tim-3) on natural killer (NK) cells increased in atherosclerotic patients and animal models. In this study, 14 patients treated with rosuvastatin and 12 patients with atorvastatin for more than 3 months were included and 20 patients without statins treatment as control. Both statins treatment reduced the expressions of Tim-3 on NK cells and their subtypes, natural killer T (NKT) cells and CD3 T cells, and increased the proportions of NKT cells among peripheral blood mononuclear cells, accompanied by the decreased levels of total cholesterol, low density lipoprotein, and increased ratios of high density lipoprotein to cholesterol. These may contribute to the functions of statins in the treatment of atherosclerosis.",
        "keywords": [
            "Tim\u22123",
            "atherosclerosis",
            "natural killer T cell",
            "natural killer cell",
            "statin"
        ],
        "authors": [
            {
                "name": "Na Zhang",
                "org": "Department of Neurology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan 250014, PR China."
            },
            {
                "name": "Min Zhang",
                "org": "Department of Neurology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan 250014, PR China."
            },
            {
                "name": "Ru-Tao Liu",
                "org": "Department of Neurology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan 250014, PR China."
            },
            {
                "name": "Peng Zhang",
                "org": "Department of Neurology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan 250014, PR China."
            },
            {
                "name": "Chun-Lin Yang",
                "org": "Department of Neurology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan 250014, PR China."
            },
            {
                "name": "Long-Tao Yue",
                "org": "Central laboratory, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan 250014, PR China."
            },
            {
                "name": "Heng Li",
                "org": "Department of Neurology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan 250014, PR China."
            },
            {
                "name": "Yong-Kang Li",
                "org": "Department of Cardiology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan 250014, PR China."
            },
            {
                "name": "Rui-Sheng Duan",
                "org": "Department of Neurology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan 250014, PR China. Electronic address: ruisheng_duan@yahoo.com."
            }
        ],
        "venue": "European journal of pharmacology",
        "year": 2017
    },
    "vYdLIZaV": {
        "id": "vYdLIZaV",
        "title": "Enhanced glycolysis contributes to the pathogenesis of experimental autoimmune neuritis.",
        "abstract": "The effects of glycolysis inhibition on both innate and adaptive immune responses and the alleviation of animal clinical symptoms indicated that enhanced glycolysis contributed to the pathogenesis of EAN. Glycolysis inhibition may be a new therapy for GBS.",
        "keywords": [
            "Experimental autoimmune neuritis",
            "Glycolysis",
            "2-Deoxy-d-glucose",
            "Inflammation"
        ],
        "authors": [
            {
                "name": "Ru-Tao Liu",
                "org": "Department of Neurology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, 250014, People's Republic of China."
            },
            {
                "name": "Min Zhang",
                "org": "Department of Neurology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, 250014, People's Republic of China."
            },
            {
                "name": "Chun-Lin Yang",
                "org": "Department of Neurology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, 250014, People's Republic of China."
            },
            {
                "name": "Peng Zhang",
                "org": "Department of Neurology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, 250014, People's Republic of China."
            },
            {
                "name": "Na Zhang",
                "org": "Department of Neurology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, 250014, People's Republic of China."
            },
            {
                "name": "Tong Du",
                "org": "Department of Neurology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, 250014, People's Republic of China."
            },
            {
                "name": "Meng-Ru Ge",
                "org": "Department of Neurology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, 250014, People's Republic of China."
            },
            {
                "name": "Long-Tao Yue",
                "org": "Central Laboratory, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, 250014, People's Republic of China."
            },
            {
                "name": "Xiao-Li Li",
                "org": "Department of Neurology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, 250014, People's Republic of China."
            },
            {
                "name": "Heng Li",
                "org": "Department of Neurology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, 250014, People's Republic of China."
            },
            {
                "name": "Rui-Sheng Duan",
                "org": "Department of Neurology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, 250014, People's Republic of China. ruisheng_duan@yahoo.com."
            }
        ],
        "venue": "Journal of neuroinflammation",
        "year": 2018
    },
    "hDh4qR9q": {
        "id": "hDh4qR9q",
        "title": "Curcumin ameliorates experimental autoimmune myasthenia gravis by diverse immune cells.",
        "abstract": "Abstract   Curcumin is a traditional Asian medicine with diverse immunomodulatory properties used therapeutically in the treatment of many autoimmune diseases. However, the effects of curcumin on myasthenia gravis (MG) remain undefined. Here we investigated the effects and potential mechanisms of curcumin in experimental autoimmune myasthenia gravis (EAMG). Our results demonstrated that curcumin ameliorated the clinical scores of EAMG, suppressed the expression of T cell co-stimulatory molecules (CD80 and CD86) and MHC class II, down-regulated the levels of pro-inflammatory cytokines (IL-17, IFN-\u03b3 and TNF-\u03b1) and up-regulated the levels of the anti-inflammatory cytokine IL-10, shifted the balance from Th1/Th17 toward Th2/Treg, and increased the numbers of NKR-P1 +  cells (natural killer cell receptor protein 1 positive cells, including NK and NKT cells). Moreover, the administration of curcumin promoted the differentiation of B cells into a subset of B10 cells, increased the anti-R97-166 peptide IgG1 levels and decreased the relative affinity indexes of anti-R97-116 peptide IgG. In summary, curcumin effectively ameliorate EAMG, indicating that curcumin may be a potential candidate therapeutic agent for MG.",
        "keywords": "",
        "authors": [
            {
                "name": "Shan Wang",
                "org": "Department of Neurology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan 250014, PR China"
            },
            {
                "name": "Heng Li",
                "org": "Department of Neurology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan 250014, PR China"
            },
            {
                "name": "Min Zhang",
                "org": "Department of Neurology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan 250014, PR China"
            },
            {
                "name": "Long-Tao Yue",
                "org": "Central Laboratory, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan 250014, PR China"
            },
            {
                "name": "C. L. Wang",
                "org": ""
            },
            {
                "name": "Peng Zhang",
                "org": ""
            },
            {
                "name": "Ying Liu",
                "org": "Electromyography Department, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan 250014, PR China"
            },
            {
                "name": "Rui-Sheng Duan",
                "org": "Department of Neurology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan 250014, PR China"
            }
        ],
        "venue": "Neuroscience Letters",
        "year": 2016
    },
    "DZnIrh6h": {
        "id": "DZnIrh6h",
        "title": "Parthenolide inhibits the initiation of experimental autoimmune neuritis",
        "abstract": "Abstract   A growing body of evidence suggests the anti-inflammatory and antitumor effects of parthenolide (PAR). Here we show that PAR treatment inhibits the initiation of experimental autoimmune neuritis (EAN), suppresses the production of TNF-\u03b1, IFN-\u03b3, IL-1\u03b2 and IL-17, and decreases Th1 and Th17 cells at early time point. However, such anti-inflammatory effect vanishes later and PAR impedes the recovery of EAN in late phase, which is accompanied with inhibited apoptosis of inflammatory cells. Our results indicate that PAR plays dual roles in EAN and it is not proper to be applied in autoimmune diseases of nervous system.",
        "keywords": "",
        "authors": [
            {
                "name": "Min Zhang",
                "org": "Department of Neurology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan 250014, PR China"
            },
            {
                "name": "Ru-Tao Liu",
                "org": "Department of Neurology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan 250014, PR China"
            },
            {
                "name": "Peng Zhang",
                "org": ""
            },
            {
                "name": "Na Zhang",
                "org": "Department of Neurology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan 250014, PR China"
            },
            {
                "name": "Chun-Lin Yang",
                "org": "Department of Neurology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan 250014, PR China"
            },
            {
                "name": "Long-Tao Yue",
                "org": "Central laboratory, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan 250014, PR China"
            },
            {
                "name": "Xiao-Li Li",
                "org": "Department of Neurology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan 250014, PR China"
            },
            {
                "name": "Yin Liu",
                "org": "Department of Neurology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan 250014, PR China"
            },
            {
                "name": "Heng Li",
                "org": "Department of Neurology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan 250014, PR China"
            },
            {
                "name": "Juan Du",
                "org": "Central laboratory, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan 250014, PR China"
            },
            {
                "name": "Rui-Sheng Duan",
                "org": "Department of Neurology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan 250014, PR China"
            }
        ],
        "venue": "Journal of Neuroimmunology",
        "year": 2017
    },
    "PF0rI1mD": {
        "id": "PF0rI1mD",
        "title": "IgG4-Related Mastoiditis, Hypertrophic Pachymeningitis and Inflammatory Pseudotumor: A Case Report and Review of the Literature",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Xiao-Li Li",
                "org": ""
            },
            {
                "name": "Xiu-Hua Wang",
                "org": ""
            },
            {
                "name": "Rui-Sheng Duan",
                "org": ""
            },
            {
                "name": "Zhan-Kui Wang",
                "org": ""
            },
            {
                "name": "Bing Yang",
                "org": ""
            },
            {
                "name": "Zhao-Xu Zhang",
                "org": ""
            },
            {
                "name": "Bin Liu",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Yan-Bin Li",
                "org": ""
            }
        ],
        "venue": "Journal of clinical & cellular immunology",
        "year": 2018
    },
    "sP089bQO": {
        "id": "sP089bQO",
        "title": "Corrigendum to: \u201clow and high doses of ursolic acid ameliorate experimental autoimmune myasthenia gravis through different pathways\u201d [Journal of Neuroimmunology 281 (2015) 61\u201367]",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Hua Xu",
                "org": ""
            },
            {
                "name": "Min Zhang",
                "org": ""
            },
            {
                "name": "Xiao-Li Li",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Long-Tao Yue",
                "org": ""
            },
            {
                "name": "Xin-Xin Zhang",
                "org": ""
            },
            {
                "name": "Cong-Cong Wang",
                "org": ""
            },
            {
                "name": "Shan Wang",
                "org": ""
            },
            {
                "name": "Rui-Sheng Duan",
                "org": ""
            }
        ],
        "venue": "Journal of Neuroimmunology",
        "year": 2019
    },
    "R6PBWuGH": {
        "id": "R6PBWuGH",
        "title": "Ginsenoside Rb1: The new treatment measure of myasthenia gravis.",
        "abstract": "Myasthenia gravis (MG) is an autoimmune neuromuscular disease characterized by fatigue and muscle weakness. Ginseng is used in the treatment of MG. Ginsenoside Rb1 (G-Rb1), the most abundant ginsenoside in ginseng root, has been proved to be immune regulatory in various diseases. In this study, we investigated the effects and mechanisms of G-Rb1 in treatment for MG in a rat model. Our data showed that G-Rb1 treatment markedly ameliorated the symptoms of experimental autoimmune myasthenia gravis (EAMG) rats, decreased the percentage of Th17 cells in mononuclear cells (MNCs), and increased the number of Treg and Th2 cells in MNCs. We also found that G-Rb1 treatment decreased the serum level of anti-R97-116 peptides IgG1 and IgG2a antibodies. Our findings provide strong evidence that G-Rb1 treatment has immune regulatory effects in EAMG rats, which indicate that G-Rb1 may be employed as a therapeutic medication for MG.",
        "keywords": [
            "Ginsenoside Rb1",
            "IL-10",
            "IL-4",
            "Myasthenia gravis",
            "Th17 cells",
            "Treg cells"
        ],
        "authors": [
            {
                "name": "Wei Chen",
                "org": "Institute of Neuroscience, Key Laboratory of Primate Neurobiology, CAS Center for Excellence in Brain Science, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China."
            },
            {
                "name": "Qing-Fang Meng",
                "org": "Department of Neurology, Second Affiliated Hospital of Shandong University of Chinese, Jinan, Shandong 250014, China."
            },
            {
                "name": "Jun-Kang Sui",
                "org": "College of Life Science, Shandong Agricultural University, Tai'an, Shandong 271000, China."
            },
            {
                "name": "Yan-Jun Wang",
                "org": "Affiliated Hospital of Taishan Medical College, Tai'an, Shandong 271000, China."
            },
            {
                "name": "Xiao-Li Li",
                "org": "Department of Neurology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, Shandong 250014, China."
            },
            {
                "name": "Shen Liu",
                "org": "Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China."
            },
            {
                "name": "Heng Li",
                "org": "Department of Neurology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, Shandong 250014, China."
            },
            {
                "name": "Cong-Cong Wang",
                "org": "Department of Neurology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, Shandong 250014, China."
            },
            {
                "name": "Chun-Hong Li",
                "org": "Department of Neurology, Jinan Municipal Hospital of CMM, Jinan, Shandong 250014, China."
            },
            {
                "name": "Yan-Bin Li",
                "org": "Department of Neurology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, Shandong 250014, China. Electronic address: 13864006933@163.com."
            }
        ],
        "venue": "International immunopharmacology",
        "year": 2016
    },
    "aGHPXUSe": {
        "id": "aGHPXUSe",
        "title": "Dimension prediction of spur gear in cold precision sizing based on elastic deformation behavior",
        "abstract": "In order to predict spur gear dimensional deviation in cold precision sizing, elastic plastic-elastic three-dimensional coupled model of spur gear and cold precision sizing die were built. The behavior of die elastic expansion and gear elastic recovery in cold precision sizing were analyzed by FEM method. The conclusion of the allocation tendency of gear dimension deviation that the amount of gear deviation increases from base circle to tooth tip circle in the direction of gear profile, while the amount of gear deviation increases from bottom to top in the axial direction. The experiment of the spur gear cold precision sizing process was proceed, the change tendency of the amount of dimension deviation of gear obtained by experiment was similar with the FEM result, the maximum relative error was 8.5%. The results provide the reference for the dimension prediction of cold precision gear and the subsequent die modification.",
        "keywords": [
            "Cold precision sizing",
            "Elastic deformation rule",
            "FEM simulation",
            "Spur gear"
        ],
        "authors": [
            {
                "name": "Rui Zhou",
                "org": "Hefei University of Technology(Hefei University of Technology),Hefei,China"
            },
            {
                "name": "Wenlin Chen",
                "org": "Hefei University of Technology(Hefei University of Technology),Hefei,China"
            },
            {
                "name": "Heng Li",
                "org": "Hefei University of Technology(Hefei University of Technology),Hefei,China"
            },
            {
                "name": "Dong Yang",
                "org": "Hefei University of Technology(Hefei University of Technology),Hefei,China"
            },
            {
                "name": "Yucheng Wu",
                "org": "Hefei University of Technology(Hefei University of Technology),Hefei,China"
            }
        ],
        "venue": "Suxing Gongcheng Xuebao/Journal of Plasticity Engineering",
        "year": 2013
    },
    "qggv8F0K": {
        "id": "qggv8F0K",
        "title": "Mass and charge transport in IPMC actuators with fractal interfaces",
        "abstract": "Ionic Polymer-Metal Composite (IPMC) actuators have been attracting a growing interest in extensive applications, which consequently raises the demands on the accuracy of its theoretical modeling. For the last few years, rough landscape of the interface between the electrode and the ionic membrane of IPMC has been well-documented as one of the key elements to ensure a satisfied performance. However, in most of the available work, the interface morphology of IPMC was simplified with structural idealization, which lead to perplexity in the physical interpretation on its interface mechanism. In this paper, the quasi-random rough interface of IPMC was described with fractal dimension and scaling parameters. And the electro-chemical field was modeled by Poisson equation and a properly simplified Nernst\u2013Planck equation set. Then, by simulation with Finite Element Method, a comprehensive analysis on he inner mass and charge transportation in IPMC actuators with different fractal interfaces was provided, which may be further adopted to instruct the performance-oriented interface design for ionic electro-active actuators. The results also verified that rough interface can impact the electrical and mechanical response of IPMC, not only from the respect of the real surface increase, but also from mass distribution difference caused by the complexity of the micro profile.",
        "keywords": "",
        "authors": [
            {
                "name": "Longfei Chang",
                "org": "Hefei Univ. of Technology (China)"
            },
            {
                "name": "Yucheng Wu",
                "org": "Hefei Univ. of Technology (China)"
            },
            {
                "name": "Zicai Zhu",
                "org": "Univ. of Tartu (Estonia)"
            },
            {
                "name": "Heng Li",
                "org": "Hefei Univ. of Technology (China)"
            }
        ],
        "venue": "Proceedings of SPIE",
        "year": 2016
    },
    "ucd73ATu": {
        "id": "ucd73ATu",
        "title": "Effect of precipitates on properties of cold-rolled Al\u2013Mg\u2013Si\u2013Sc\u2013Zr alloy with higher temperature aging",
        "abstract": "ABSTRACTThe aging hardening behaviours of the cold-rolled Al\u2013Mg\u2013Si\u2013Sc\u2013Zr alloy were investigated. The microstructure, hardness and electrical conductivity (EC) of the Al\u2013Mg\u2013Si\u2013Sc\u2013Zr alloy were measured. The relationship between the microstructure and the properties of the Al\u2013Mg\u2013Si\u2013Sc\u2013Zr alloy with cold-rolling and aging processes was studied. The result shows that the addition of Sc and Zr elements significantly refines the grains of the Al\u2013Mg\u2013Si alloy during casting. The cold rolling promotes the Al\u2013Sc(Zr) precipitation. The precipitate strengthening increases with increasing roll reduction. The EC of the cold rolling\u2009+\u2009aging Al\u2013Mg\u2013Si\u2013Sc\u2013Zr alloy increases with increasing rolling reductions. The combination effects of the precipitation hardening and DRX softening during the aging process lead to the similar peak hardness values of around 70\u2009HV of the rolled Al\u2013Mg\u2013Si\u2013Sc\u2013Zr alloy with the different reductions.",
        "keywords": "",
        "authors": [
            {
                "name": "Ming Li",
                "org": " Department of Materials Science and Engineering, Hefei University of Technology, Hefei, People's Republic of China"
            },
            {
                "name": "Ming Li",
                "org": " Department of Materials Science and Engineering, Hefei University of Technology, Hefei, People's Republic of China"
            },
            {
                "name": "Heng Li",
                "org": " Institute of Industry and Equipment Technology, Hefei University of Technology, Hefei, People's Republic of China"
            },
            {
                "name": "Zhen Zhang",
                "org": " Department of Materials Science and Engineering, Hefei University of Technology, Hefei, People's Republic of China"
            },
            {
                "name": "Wenchao Shi",
                "org": " Institute of Industry and Equipment Technology, Hefei University of Technology, Hefei, People's Republic of China"
            },
            {
                "name": "Jiaqin Liu",
                "org": " Institute of Industry and Equipment Technology, Hefei University of Technology, Hefei, People's Republic of China"
            },
            {
                "name": "Yue Hu",
                "org": " Institute of Industry and Equipment Technology, Hefei University of Technology, Hefei, People's Republic of China"
            },
            {
                "name": "Yucheng Wu",
                "org": " Department of Materials Science and Engineering, Hefei University of Technology, Hefei, People's Republic of China"
            }
        ],
        "venue": "Materials Science and Technology",
        "year": 2018
    },
    "dpPz7vIp": {
        "id": "dpPz7vIp",
        "title": "The influence of twinning on plastic constitutive description of a magnesium alloy",
        "abstract": "Abstract During uniaxial compression tests of a twin-roll cast AZ31 alloy, the orientation induced anisotropy only lay in the initial strain range, which was attributed to the different twinning systems that were involved. Regardless of the initial orientation, contraction twinning always played an important role at higher strain range, especially with higher strain rate and lower temperature. At temperature higher than 300 \u00b0C, dynamic recrystallization would dominate. A single modified Arrhenius equation \u220a\u02d9=[ sinh\u2061(\u03b1\u03c3) ]nexp\u2061(\u2212Q/RT) was used to describe the flow behavior for all experimental conditions. The n value was found to be higher at lower temperature when compression twinning was prevalent. Meanwhile the deformation activation energy was somewhat lower, which was attributed to the twinning induced softening effect.",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": "School of Materials Science and Engineering, Hefei University of Technology, Hefei, P.R. China"
            },
            {
                "name": "Zhao Liu",
                "org": "School of Materials Science and Engineering, Hefei University of Technology, Hefei, P.R. China"
            },
            {
                "name": "Zhen Zhang",
                "org": "School of Materials Science and Engineering, Hefei University of Technology, Hefei, P.R. China"
            },
            {
                "name": "Jinhua Peng",
                "org": "School of Materials Science and Engineering, Hefei University of Technology, Hefei, P.R. China"
            },
            {
                "name": "Yaozu Li",
                "org": "School of Materials Science and Engineering, Hefei University of Technology, Hefei, P.R. China"
            },
            {
                "name": "Peng Guo",
                "org": "School of Materials Science and Engineering, Hefei University of Technology, Hefei, P.R. China"
            },
            {
                "name": "Yucheng Wu",
                "org": "School of Materials Science and Engineering, Hefei University of Technology, Hefei, P.R. China"
            }
        ],
        "venue": "International Journal of Materials Research",
        "year": 2018
    },
    "KHVb7q0b": {
        "id": "KHVb7q0b",
        "title": "A novel spinning process for simultaneously producing two cone parts with big angle",
        "abstract": "ABSTRACTA new spinning forming method for simultaneously producing two cone parts with big angle was developed. The novel process with three passes was generated. The 3D finite element (FE) model of cone parts was established using ABAQUS software. Based on the metal plastic forming principle and the characteristic of spinning, technical parameters including the angle of forming surface and the radial feed speed of the roller, the spindle speed and the friction coefficient were determined. Based on the secondary development of above FE model, the fittability of cone parts was obtained, which is of great significance for improving the performance of cone parts.",
        "keywords": "",
        "authors": [
            {
                "name": "Ming Li",
                "org": "Department of Materials Science and Engineering, Hefei University of Technology, Hefei, China"
            },
            {
                "name": "Ming Li",
                "org": "Department of Materials Science and Engineering, Hefei University of Technology, Hefei, China"
            },
            {
                "name": "Yuanyi Xu",
                "org": "Institute of Industry and Equipment Technology, Hefei University of Technology, Hefei, China"
            },
            {
                "name": "Heng Li",
                "org": "Institute of Industry and Equipment Technology, Hefei University of Technology, Hefei, China"
            },
            {
                "name": "Hongji Wang",
                "org": "Department of Materials Science and Engineering, Hefei University of Technology, Hefei, China"
            },
            {
                "name": "Hongji Wang",
                "org": "Department of Materials Science and Engineering, Hefei University of Technology, Hefei, China"
            },
            {
                "name": "Wenchao Shi",
                "org": "Institute of Industry and Equipment Technology, Hefei University of Technology, Hefei, China"
            },
            {
                "name": "Yucheng Wu",
                "org": "Laboratory of Non-Ferrous Metals and Processing Engineering of Anhui Province, Hefei University of Technology, Hefei, China"
            }
        ],
        "venue": "Journal of The Chinese Institute of Engineers",
        "year": 2018
    },
    "GLKkiceA": {
        "id": "GLKkiceA",
        "title": "A polymer scaffold for self-healing perovskite solar cells",
        "abstract": "Advancing of the lead halide perovskite solar cells towards photovoltaic market demands large-scale devices of high-power conversion efficiency, high reproducibility and stability via low-cost fabrication technology, and in particular resistance to humid environment for long-time operation. Here we achieve uniform perovskite film based on a novel polymer-scaffold architecture via a mild-temperature process. These solar cells exhibit efficiency of up to ~16% with small variation. The unencapsulated devices retain high output for up to 300\u2009h in highly humid environment (70% relative humidity). Moreover, they show strong humidity resistant and self-healing behaviour, recovering rapidly after removing from water vapour. Not only the film can self-heal in this case, but the corresponding devices can present power conversion efficiency recovery after the water vapour is removed. Our work demonstrates the value of cheap, long chain and hygroscopic polymer scaffold in perovskite solar cells towards commercialization. The rapid rising of the lead halide perovskite solar cells (PSCs), typically based on CH3NH3PbI3 (MAPbI3) or its analogues, demonstrate great potential for market applications1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13. The worldwide power conversion efficiency (PCE) race for the perovskite solar cells has stimulated the highest record of >20% update via solvent engineering8, interface engineering5 and composition engineering10, which approaches the best of polycrystalline silicon modules. The excellent performance of PSCs is attributed to the high absorption coefficient, weak exciton binding energy, and long diffusion length of the perovskite phase12, 14, 15, 16, 17. Two dominant device architectures, namely mesoporous scaffold1, 2, 3 and planar heterojunction structures4, 5 have been developed. The PCE in mesoporous scaffold architecture depends on the pore size, porosity and morphology of the metal oxide nanoparticles, which dominantly determine the coverage, morphology variation of the perovskite layer and the carrier lifetime. Moreover, the fabrication of inorganic metal oxide mesoporous scaffold is complicated and needs sintering at high temperature of >450\u2009\u00b0C (refs 2, 3), which makes the fabrication more expensive. The planar heterojunction PSCs fabricated layer by layer is either fabricated via high vacuum deposition4 or solution-based method5, 18. However, the low-cost solution process is rather challenging to form homogeneous film due to the dewetting process and sensitivity to the atmosphere18, 19, 20. Recently, progress has been reported to control the nucleation rate by changing dissolvent or temperature of the substrate21, 22. Besides high efficiency and high reproducibility, long-term stability is also a crucial barrier to commercialize the PSCs, because the lead halide perovskite materials are very sensitive to ambient humidity and easy to dissolve and degrade in humid environment5, 23, 24. Therefore, it is very challenging and pressing to develop ultra stable and high PCE devices resistant to hostile operation environment. Here we report a novel perovskite solar cell architecture based on an insulating polymer scaffold structure. The polymer-scaffold perovskite layer is simply fabricated via a single one-step process under mild temperature of 105\u2009\u00b0C. The as-made polymer-scaffold perovskite solar cell (PPSC) devices demonstrate high PCE up to ~16% under standard AM1.5 illumination and very small efficiency variation compared with that without the insulating polymer. Remarkably, unsealed PPSCs exhibit excellent performance in stability test in highly humid environment (70% relative humidity), which can endure the moisture for over 300\u2009h. Most strikingly, the PPSCs show strong self-healing or water resistant effect under vapour spray. The perovskite film, as well as the corresponding devices can recover rapidly to its original phase and performance after being vapour sprayed and dried in ambient air, respectively. The PPSC architecture inherits the basic structure of PSCs with inorganic mesoporous scaffold1, 2, 3, instead, the inorganic nanocrystal scaffolds are replaced with long- and flexible-polymer chain networks, which can be processed under mild temperature (Fig. 1a\u2013c). The fabrication of PPSC is similar to that of planar heterojunction PSCs, except for the precursor solution preparation (Fig. 1d). Long-chain insulating polymers, dissolved in precursor solution, assemble the polymer scaffold simultaneously as the precursor solution is spin coated on the substrate. The selected polymer should be chemically inert to ingredients for perovskite synthesis; it should also act as an electrical insulator to guarantee the effective transport of photo-generated carriers. Here polyethylene glycol (PEG), which meets the requirements, is chosen to be added in the precursor solution of PbCl2 and CH3NH3I (MAI; 1:3 molar ratio) in dimethylformamide. The molar ratio of PEG monomers (C2H4O) to ultimate product MAPbI3 is close to 1:1 (PEG in 40\u2009mg\u2009ml\u22121). The PEG scaffold perovskite absorber layer was prepared on the TiO2 (~40\u2009nm thickness)-coated fluorine doped tin oxide (FTO) glass by spin coating followed by annealing at 105\u2009\u00b0C for 70\u2009min. 2,29,7,79-tetrakis-(N,N-di-p-methoxyphenylamine)9,99-spirobifluorene (Spiro-OMeTAD) and gold were used as the hole transport layer and electrode, respectively. Figure 1e,f present top-view scanning electron microscope (SEM) images of the perovskite films without and with polymer scaffold. Those without scaffold exhibited large pinholes and bare conducting substrates, increasing the risk of short circuits. Those with scaffold demonstrated continuous and complete coverage. The cross-section SEM image showed the perovskite layer without polymer to have considerable variation in thickness and many voids (Fig. 1g). The film with polymer was uniform in thickness over large area (Fig. 1h). The PEG scaffold can also work in another precursor solution PbI2:MAI (1:1) (Supplementary Fig. 1). PEG plays an important role in improvement of the film quality for the following reasons. First, the simultaneously formed PEG scaffold, which is formed by entangled long-chain molecules, acts as a three-dimensional skeleton to support perovskite crystals, causing it to cover the substrate more uniformly (Fig. 1c), demonstrating an advantage over planar heterojunction PSCs. Uniformly distributed PEG scaffolds function as Al2O3 scaffolds3, and they can be produced in a much simpler and less costly manner. Second, the wetting properties of the precursor solution have been improved after introducing PEG (Supplementary Fig. 2), which can improve film morphology19. Third, PEG molecules in precursor solution can slow down the crystallization of perovskite from the X-ray diffraction characterization by tracking the intermediate phase in the crystallization process, which is shown below. To confirm that PEG acts as scaffold in the architecture, detailed energy dispersive spectroscopy (EDS) analysis in a Cs-corrected scanning transmission electron microscope (STEM) was conducted for element mapping investigation (Fig. 2a\u2013c). The high-angle annular dark field (HAADF) STEM image (Fig. 2a) reveals that the perovskite crystalline grains are surrounded by polymer material. The profiles of perovskite grains are highlighted with dashed lines according to the EDS mapping of Pb component (Fig. 2b). The amorphous material surrounding the perovskite grains is PEG in accordance with the EDS mapping of O element because only PEG contains O. The O mapping demonstrates that PEG not only covers the perovskite grains, but also cross-links the neighbouring perovskite grains via self-assembly forming a polymer-scaffold network to support the perovskite grains (Fig. 2c). Above conclusion is also evidenced by the fact that O mapping covers larger area than Pb and extends from crystal boundaries, indicating that the perovskite grains are imbedded in the PEG networks, corresponding well to the HAADF\u2013STEM image. In addition, the O element mapping on the cross-sectional area of the PPSC film confirms a homogeneous distribution of PEG molecules in the perovskite film (Supplementary Fig. 3). High-resolution transmission electron microscope image of perovskite grain demonstrates good crystal lattice (Supplementary Fig. 4), suggesting that PEG molecules do not damage the perovskite crystal structure. The phase evolution of PEG scaffold perovskite film during annealing was characterized by X-ray diffraction analysis (Fig. 2d). Over the course of 30\u201350\u2009min, the film turned from orange to yellow, the (110) and (220) peaks of perovskite phase25, 26 became more pronounced and some new peaks appeared between 10 and 20\u00b0. The intermediate phase disappeared after annealing for 60\u2009min, and the sample became deep black at 105\u2009\u00b0C after 70\u2009min of annealing, with stronger (110) and (220) peaks. X-ray diffraction patterns of perovskite film without PEG and with PEG under the same 100\u2009\u00b0C sintering temperature are also shown in Supplementary Fig. 5. Note that intermediate phase disappears after 70\u2009min in film without PEG. While in film with PEG, intermediate phase disappears after 90\u2009min (Supplementary Note 1), which strongly suggests a slower crystallization process in PEG scaffold perovskite film. Photoluminescence (PL) spectra were measured to verify whether excess recombination sites and defect states are induced in the PEG scaffold perovskite film27, 28. Compared with the PL spectrum of pristine perovskite film, the intensity is not influenced after being coated with PEG (Fig. 3b), indicating the insulating nature of PEG, as shown in Fig. 3a. Figure 3c shows the time-resolved PL spectra with and without PEG polymer scaffold, with the similar carrier lifetime by using single exponential fitting (110.8\u2009ns with PEG, 120.1\u2009ns without PEG). This result indicates ~1\u2009\u03bcm diffusion length if diffusion coefficient is supposed to be 0.1\u2009cm2\u2009s\u22121, which is sufficient to guarantee effective collection efficiency. On the other hand, no visible shift (peak position of 760\u2009nm) and broadening (half width of 40\u2009nm) of peaks associated with perovskite layers with and without PEG scaffold is observed, indicating that PEG does not induce any excessive recombination (Supplementary Fig. 6). The photovoltaic properties of PPSCs are characterized systematically. The PEG molecular weight and its concentration in precursor solution were found to play an important role in the performance of PPSCs. Figure 4a shows the current density\u2013voltage (J\u2013V) curves of samples with PEG in different molecule weights (12,000/20,000/100,000\u2009Da) measured under simulated AM1.5 illumination of 100\u2009mW\u2009cm\u22122. The molecular weight of PEG, proportional to the length of polymer, has a significant effect on the performance of PPSCs, and the optimal molecular weight was found to be >20,000\u2009Da because longer PEG molecules facilitate the formation of three-dimensional molecular network in the perovskite film, and guarantee uniform morphology. PEG concentration is also critical to devices because it is related to the series resistance. As demonstrated in Fig. 4b, the device shows much better performance with 20 and 40\u2009mg\u2009ml\u22121 PEG concentration, and its PCE decreases at higher concentrations (80\u2009mg\u2009ml\u22121) because the excess PEG in the film increases the series resistance and lowers the efficiency. Note that viscosity of the solution can be strongly influenced by PEG concentration and molecule weight, so the r.p.m. value of spin coating is optimized at different PEG concentration and molecule weight (see Methods for details) to guarantee ~400\u2009nm film thickness. The improved efficiency was also consistent with the increased recombination time constant28 in PPSCs, compared with that of control devices, as is shown in Fig. 4c. Owing to the improved coverage, the recombination time is almost one order of magnitude larger than that without polymer scaffold at zero bias. The highest PCE of 16% was obtained for PPSCs with optimal PEG molecule weight of 20,000\u2009Da and concentration of 20\u2009mg\u2009ml\u22121, and showed an open voltage (Voc) of 0.98\u2009V, short-circuit current (Jsc) of 22.5\u2009mA\u2009cm\u22122, and fill factor of 0.72 (Supplementary Fig. 7a). Another representative device shows a steady-state PCE of 15.4% at first 10\u2009s, and the PCE gradually drops down and eventually stabilized at 13.5% in 1,000\u2009s (0.7\u2009V bias, Supplementary Fig. 7b). Parallel devices present H value from 10 to 30% under 500\u2009mV\u2009s\u22121 if hysteresis index is defined H=(PCEreverse\u2212PCEforward)/PCEreverse \u00d7 100% to characterize the hysteresis effect. PCEreverse and PCEforward represent PCE obtained from J to V measurement in reverse scan and forward scan, respectively. The statistical PCE distributions of >100 samples without and with (for two concentrations) polymer scaffolds are shown in Fig. 4d. The PPSCs exhibited a narrow PCE distribution for 20 and 40\u2009mg\u2009ml\u22121, with an average efficiency of 14 and 12.5%, respectively, but the PCE distribution of the PSCs without polymer scaffold was much broader, varying from 2 to 14%, averaging at ~8%. The significant increase in PCE and high reproducibility of the PPSC devices are direct reflections of the uniform thickness and homogeneous morphology of the polymer-scaffold perovskite layer. More importantly, the insulating PEG scaffold structure can stabilize the PSCs in humid environment due to the strong hygroscopicity property of PEG. Here three groups of unsealed devices were prepared without and with PEG (two concentrations), respectively. Figure 5a shows the PCE evolution as a function of time of the three groups of devices in the dark under highly humid environment (relative humidity 70%) without any sealing. In contrast to the fast PCE decay from 12 to 0.5% within 50\u2009h of the pristine PSCs, the PPSCs retained 65% of its PCE after 300\u2009h aging. Similarly, the Jsc, Voc, and fill factor of the pristine sample decreased quickly during the first 50\u2009h, while those of the PPSCs retained relatively high values for up to 300\u2009h (Supplementary Fig. 8a,b). Note that the device with PEG concentration of 40\u2009mg\u2009ml\u22121 showed better performance than the one with 20\u2009mg\u2009ml\u22121 because more PEG can form a more compact layer, enhancing the moisture resistance of devices. We also studied the stability under continuous light illumination in 70% humidity for unsealed devices (Supplementary Fig. 8c,d). Photovoltaic performance degraded quickly within 10\u2009h in the device without PEG scaffold, while PPSC retained 83% of its PCE during the same aging period. Similarly, Voc, Jsc, and fill factor suffered substantial decrease in the first 10\u2009h for pristine sample while they remained relatively high values in the presence of PEG. X-ray diffraction patterns of the perovskite film with PEG scaffold showed no structure destruction after 72\u2009h continuous light irradiation, while the samples without PEG degraded into PbI2 quickly within 10\u2009h (Supplementary Fig. 9). Evidence above strongly suggests that PEG can greatly protect perovskite film from decomposition under moisture attack and significantly improve the stability of PPSCs at very humid environment. In addition to its improved stability, the PPSC devices can demonstrate a self-healing behaviour and humidity resistance effect on exposure to water vapour. Figure 5b shows a comparison of the changes in colour of the perovskite layer with PEG (top) and the perovskite layer without PEG (bottom) after both were sprayed with water vapour for 60\u2009s. The perovskite film without PEG decomposed into PbI2 and turned yellow irreversibly. In contrast, the PEG scaffold perovskite film showed yellow in colour at first and recovered to black in ~45\u2009s after removing from the spray (Fig. 5b). This amazing self-healing behaviour is further vividly demonstrated in 120\u2009s videos (Supplementary Movies 1 and 2). The self-healing capability of the PPSC device was also manifested in the J\u2013V characterization (Fig. 5c). The PCE degrades with smaller Voc and Jsc after exposure to water vapour for 60\u2009s. Surprisingly, results showed that the J\u2013V curve can almost regain its original value in 45\u2009s, indicating that the PPSCs can heal itself when it is returned to ambient air after being sprayed with water. This unique humidity-resist characteristic is very suitable for practical applications because once the devices are exposed to very humid environment; they can self-heal to high PCE again in a short time when they return to sunlight again. Moreover, to further prove the self-healing property, perovskite film with PEG was sprayed with water vapour for 60\u2009s, then after self-healing, it was coated by Spiro-MeOTAD and Au electrode to fabricate into corresponding device, which showed photovoltaic performance comparable to its original PPSC devices without water spray (Supplementary Fig. 10). The self-healing process was recorded by X-ray diffraction analysis (Fig. 5d). The peak at 12.7\u00b0 reveals that PbI2 phase formed when water vapour was sprayed on the film. After self-healing, the PbI2 peak disappeared and the perovskite film fully recovered to its original crystal phase. The self-healing can also be demonstrated by the absorption spectra (Fig. 5e), which presented the same absorbance and similar Urbach energy (~40\u2009meV; ref. 29). The decomposition of perovskite phase is caused by the chemical reaction with water molecules30, 31, 32, which is manifested by the X-ray diffraction analysis of the perovskite film without PEG after water spray (Supplementary Fig. 11). According to the observations in Fig. 2a\u2013c, we conjecture that these entangled PEG molecules are anchored on the surface of perovskite grains by hydrogen bonding, and the formation is illustrated in Fig. 6a. The \u2013OH I\u2013interaction had been evidenced in the work by Li et al32. We use liquid state 1H NMR measurements to prove such interactions. The proton NMR spectra of three samples were compared (Fig. 6b): deuterated DMSO solution with MAPbI3 (sample 1), with MAPbI3+PEG (sample 2) and with PEG (sample 3). In the signals of sample 3, double methylene group linked to oxygen on both ends (\u2013[O\u2013CH2\u2013CH2]n\u2013) is characterized by the peak at \u03b4=3.48\u2009p.p.m. (Fig. 6b). An upfield chemical shift of \u0394\u03b4 ~\u22120.18\u2009p.p.m. with several splitting peaks is observed in sample 2. Such chemical shift can be explained by the hydrogen bond between MA+ and O in PEG chain, which weakens the influence of O on protons of methylene in \u2013[O\u2013CH2\u2013CH2]n\u2013. Furthermore, the proton resonance signals of \u2013NH3+ in sample 1 (peak at \u03b4=7.33\u2009p.p.m.) shift towards upfield with \u0394\u03b4~ \u22120.13\u2009p.p.m. in sample 2 (Fig. 6b), which can also be attributed to the hydrogen bonds discussed above. Such interaction is also evidenced by a dissolution experiment devised by us (Supplementary Fig. 12). As presented in Fig. 6c, the improved stability and self-healing effect of the PPSC devices can be ascribed to the excellent hygroscopicity of the PEG molecules and their strong interaction with the perovskite. On one hand, the omnipresent PEG molecules can absorb water efficiently to form a compact moisture barrier around perovskite crystal grains with little water penetrating into the film. On the other hand, on water spray, the black perovskite film with PEG turned light yellow (PbI2 forms) at first. However, due to the strong interaction between MAI and PEG, (NMR measurements and a dissolution experiment in Supplementary Fig. 12), the MAI molecules were anchored by the nearby PEG molecules rather than escape away (process 1, 2 in Fig. 6c). After being kept away from water vapour, PbI2 in the film reacted with nearby MAI to regenerate the perovskite MAPbI3 phase, very similar to the two-step synthesis2 (process 3 in Fig. 6c). The instant decomposition-regeneration mechanism explains the fast self-healing process in the PEG scaffold perovskite film. The hygroscopic PEG scaffold can stabilize the perovskite film, rendering the devices resistant to moisture with strong self-healing property. Hygroscopic polymer-scaffold architecture paved a new effective way in perovskite solar cell, to solve the hydrolysis problem in ambient air with greatly decreased package cost. The polymer-scaffold perovskite layer reinforces the architecture and improves strain tolerance. It may also facilitate production of flexible, wearable devices in the future. Future work will be focused on looking for cheap long-chain polymers which have stronger hygroscopicity and binding effect with MAI to protect the perovskite from decomposition in ambient environment. Moreover, by comparing the stability test result under light illumination (Supplementary Fig. 8) and in dark (Fig. 5a), we found that light has a strong destructive influence on stability performance. One would expect that this influence comes from decomposition of perovskite film accelerated by light with the aid of hydrolysis by water molecules under illumination (reactive equation in Supplementary Fig. 11). However, after 72\u2009h light soaking, the perovskite film with PEG was not destructed compared with that without PEG from X-ray diffraction spectra (Supplementary Fig. 9). This indicated another important factor influencing the efficiency in addition to material decomposition. Hence, we speculate that I\u2212 ion migration33, 34, 35, 36 may be induced or enhanced by light. Ion migration may answer for the poor stability under illumination, no matter in the traditional architecture without PEG scaffold or in our PPSCs, which needs further investigation. Further improvement needs be focused on revealing the mechanism of ion migration in the long-term stability issue, as well as how to inhibit it in PPSCs, which would lead to much better performance in stability test under illumination with high humidity. All chemicals were purchased from Sigma-Aldrich or J&K Scientific Ltd. unless otherwise stated. The photovoltaic devices were fabricated on FTO-coated glass (Pilkington, Nippon Sheet Glass). First, laser-patterned, FTO-coated glass substrates were cleaned by ultrasonic cleaned in deionized water, acetone and ethanol, followed by an ultraviolet treatment for 5\u2009min. Compact layers were deposited on the substrates by spin coating titanium diisopropoxide bis(acetylacetonate) solution (75% in 2-propanol) diluted in ethanol (1:20, volume ratio) for two times and annealed at 450\u2009\u00b0C for 30\u2009min. After cooling to room temperature, the substrates were transferred to a hot plate at 90\u2009\u00b0C before spin coating. CH3NH3I was synthesized according to the reported procedure1. In a typical synthesis, 33.77\u2009ml methylamine (33% in methanol) and 30\u2009ml of hydroiodic acid (57% in water) were reacting in a 250\u2009ml flask at 0\u2009\u00b0C for 2\u2009h under stirring. The precipitate was formed by evaporation at 50\u2009\u00b0C for 1\u2009h. The product, methylammonium iodide CH3NH3I, was washed with diethyl ether by stirring the solution for 30\u2009min, repeated three times, and then finally dried at 60\u2009\u00b0C in vacuum oven for 24\u2009h. The prepared CH3NH3I, PbCl2 (Aldrich) (3:1) for 430 and 250\u2009mg\u2009ml\u22121 solution was mixed with PEG (Sigma-Aldrich) and stirred in dimethylformamide at 60\u2009\u00b0C for 12\u2009h. The molar ratio of PEG monomers (C2H4O) to ultimate product MAPbI3 is ~1:1 (PEG in 40\u2009mg\u2009ml\u22121). The resulting solution was then coated onto the TiO2/FTO substrate by spin coating at 500\u2009r.p.m. for 10\u2009s, and then 3,500/4,500/5,500\u2009r.p.m. for 30\u2009s, for the solution with 20/40/80\u2009mg\u2009ml\u22121 PEG, respectively. For different molecular weight 12,000/20,000/100,000\u2009Da. with 20\u2009mg\u2009ml\u22121, we use the optimized 3.500/3.500/4.500\u2009r.p.m. to prepare the film. Then the substrate was dried on a hot plate at 60\u2009\u00b0C for 45\u2009min, then sintered at 105\u2009\u00b0C for 70\u2009min. For the preparation of peroskite film without PEG, the optimized sintering temperature is 100\u2009\u00b0C. After cooling to room temperature, the hole transport material was spin coated onto the perovskite film at 3,000\u2009r.p.m. for 40\u2009s. The spin coating formulation was prepared by dissolving 72.3\u2009mg 2,2\u2032,7,7\u2032-Tetrakis(N,N-p-dimethoxy-phenylamino)-9,9\u2032-spirobifluorene(spiro-MeOTAD), purchased from Yingkou OPV Tech New Energy Co. Ltd., 30\u2009\u03bcl 4-tert-butylpyri-dine and 20\u2009\u03bcl of a stock solution of 520\u2009mg\u2009ml\u22121 lithium bis (trifluoromethylsulphonyl) imide in acetonitrile in 1\u2009ml chlorobenzene. Finally, 90-nm-thick gold electrodes were deposited on top of the devices by evaporation at ~10\u22124\u2009mbar. The active area of the electrode was fixed at 9\u2009mm2. The surface morphology and EDS mapping of the perovskite thin film was characterized by SEM (Nano430, FEI). The instrument uses an electron beam accelerated at 15\u2009kV, enabling operation at a variety of currents. Considering that only PEG polymer contains oxygen element among those materials used in perovskite thin film synthesis, here oxygen stands for PEG polymer, lead for perovskite. HAADF\u2013STEM is examined by Cs-corrected FEI (Titan G2 80\u2013200) transmission electron microscope operating at an accelerating voltage of 300\u2009kV, equipped with ChemiSTEM EDS detector, which enables very quick high-resolution element mapping. The sample is prepared from perovskite precursor solution spin coated on TEM grid (3,000\u2009r.p.m.), then annealed at 105\u2009\u00b0C for 70\u2009min. For NMR measurement, it is examined by Bruker 600 UltraShield using pulse signal. We use deuterated DMSO as solvent. The CH3NH3PbI3 solution is prepared from CH3NH3I, PbI2 (Aldrich; 1:1) for 53 and 153\u2009mg\u2009ml\u22121 solution and stirred in DMSO at 60\u2009\u00b0C for 12\u2009h. CH3NH3PbI3 solution mixed with PEG (Sigma-Aldrich) is prepared by adding 40\u2009mg PEG (molecule weight: 20,000\u2009Da) to 1\u2009ml CH3NH3PbI3 solution. For X-ray diffraction measurement, flat PbI2 and TiO2/PbI2 nanocomposites were deposited on glass slides using the above-mentioned procedures. X-ray powder diagrams were recorded on an X\u2019PertMPD PRO from PANalytical equipped with a ceramic tube (Cu anode, \u03bb=1.5406\u2009\u00c5), a secondary graphite (002) monochromator and a RTMS X\u2019Celerator detector, and operated in BRAGG-BRENTANO geometry. The samples were mounted without further modification, and the automatic divergence slit and beam mask were adjusted to the dimensions of the thin films. A step size of 0.008 deg was chosen and an acquisition time of up to 7.5\u2009min per deg. A baseline correction was applied to all X-ray powder diagrams to remove the broad diffraction peak arising from the amorphous glass slide. Steady-state PL spectra were measured using a He\u2013Cd laser (325\u2009nm in wavelength) and green laser (514\u2009nm in wavelength) guided by a micro-zone confocal Raman spectroscope (Renishaw inVia microRaman system) as the laser beam with a spot size diameter of 2\u2009\u03bcm. The collected duration is ~5\u2009ms. The time-resolved fluorescence spectra were recorded with a high-resolution streak camera system (Hamamatsu C10910). We used an amplified mode-lock Ti: Sapphire femtosecond laser system (Legend, Coherent) and a two-stage optical parametric amplifier (OperA Solo, Coherent) to generate the pump beam with a repetition rate of 1\u2009KHz. All the samples were excited by 517\u2009nm at room temperature with 110\u2009nJ\u2009cm\u22122. The electrochemical impedance spectrum and cyclic voltammograms were measured using a potentiostat/galvanostat (SP-150, Bio-Logic, France). The frequency can be tuned from 0.1\u2009Hz to 1\u2009MHz. All the samples were measured under 10\u2009mW\u2009cm\u22122. The J\u2013V characteristics were obtained using an Agilent B2900 Series precision source/measure unit, and the cell was illuminated by a solar simulator (Solar IV-150A, Zolix) under AM1.5 irradiation (100\u2009mW\u2009cm\u22122). Light intensity was calibrated with a Newport calibrated KG5-filtered Si reference cell. We use black mask to define the cells\u2019 area, and the masking effect is confirmed by testing the Jsc with and without it, which has a 5% Jsc difference. The J\u2013V curves are tested from 1.5 to \u22120.2\u2009V with a scan velocity 500\u2009mV\u2009s\u22121. The masked active area is 9\u2009mm2. Unsealed PPSCs and PSCs were put near a humidifier to control its relative humidity ~70%. For the stability test under dark, the cells were stored in a black box with 70% relative humidity, and were tested every 8\u2009h. For the stability tests under continuous light illumination, light source ranges from 300 to 800\u2009nm wavelength with 70\u2009mW\u2009cm\u22122 was used. J\u2013V curves were recorded under AM1.5 light irradiation. The temperature is controlled ~30\u2009\u00b0C. Three devices were measured in this way and demonstrate excellent repeatability. For the self-healing behaviour, we sprayed the water vapour for 60\u2009s onto the resulting devices by humidifier. J\u2013V curves were collected before and right after water vapour exposure under standard illumination AM1.5. How to cite this article: Zhao, Y. et al. A polymer scaffold for self-healing perovskite solar cells. Nat. Commun. 7:10228 doi: 10.1038/ncomms10228 (2016). Download references We thank Jinlong Pan, Professor Dongsheng Xu, Dr Zhenxuan Zhao, Professor Jianjun Tian, Professor Guozhong Cao and Professor Han Zhang for experimental help. We thank Yu Li and Professor Shufeng Wang for time-resolved PL measurements. We thank Professors Jixue Li and Ze Zhang for STEM observations. We also thank Professors Jun Xu, Liping You and Li Chen for electron microscope help. This work was supported by National 973 projects (2013CB932602, 2011CB707601, MOST) from Ministry of Science and Technology, China, National Natural Science Foundation of China (NSFC51272007, 61571015, 11234001, 91433102, 11327902). Q.Z. acknowledges Beijing Nova Program (XX2013003) and the Program for New Century Excellent Talents in University of China.",
        "keywords": [
            "Chemical sciences",
            " Materials science",
            " Applied physics"
        ],
        "authors": [
            {
                "name": "Yicheng Zhao",
                "org": "Collaborative Innovation Center of Quantum Matter, Beijing, 100084, China;State Key Laboratory for Mesoscopic Physics, School of Physics, Peking University, Beijing, 100871, China"
            },
            {
                "name": "Jing Wei",
                "org": "Collaborative Innovation Center of Quantum Matter, Beijing, 100084, China;State Key Laboratory for Mesoscopic Physics, School of Physics, Peking University, Beijing, 100871, China"
            },
            {
                "name": "Heng Li",
                "org": "Collaborative Innovation Center of Quantum Matter, Beijing, 100084, China;State Key Laboratory for Mesoscopic Physics, School of Physics, Peking University, Beijing, 100871, China"
            },
            {
                "name": "Yin Yan",
                "org": "Collaborative Innovation Center of Quantum Matter, Beijing, 100084, China;State Key Laboratory for Mesoscopic Physics, School of Physics, Peking University, Beijing, 100871, China"
            },
            {
                "name": "Wenke Zhou",
                "org": "Collaborative Innovation Center of Quantum Matter, Beijing, 100084, China;State Key Laboratory for Mesoscopic Physics, School of Physics, Peking University, Beijing, 100871, China"
            },
            {
                "name": "Dapeng Yu",
                "org": "State Key Laboratory for Mesoscopic Physics, School of Physics, Peking University, Beijing, 100871, China"
            },
            {
                "name": "Qing Zhao",
                "org": "Collaborative Innovation Center of Quantum Matter, Beijing, 100084, China;State Key Laboratory for Mesoscopic Physics, School of Physics, Peking University, Beijing, 100871, China"
            },
            {
                "name": "Dapeng Yu",
                "org": "Collaborative Innovation Center of Quantum Matter, Beijing, 100084, China"
            }
        ],
        "venue": "Nature Communications",
        "year": 2016
    },
    "CBJX7XkN": {
        "id": "CBJX7XkN",
        "title": "Suppressed hysteresis and improved stability in perovskite solar cells with conductive organic network",
        "abstract": "Advancing lead halide perovskite solar cells to photovoltaic application requires reproducible and stable devices using low-cost fabricating techniques. Here a device structure is developed with organic network uniformly incorporated into the organic/inorganic hybrid perovskite film by one-step solution-processing strategy, which significantly improves the photovoltaic performance and long-term stability of planar type perovskite solar cells. The organic network is composed with PCBM and PEG. Therein, a long-chain insulating polymer PEG acts as a network to improve film morphology, as well as device stability. The fullerene derivative PCBM in the composite forms conducting channels to assist the charge transfer and transport in perovskite film. Besides, PCBM in perovskite film can passivate trap states on grain boundaries, so that the photocurrent hysteresis of the device is suppressed significantly. This organic composite network enhances the photovoltaic performance of perovskite solar cells with maximum power conversion efficiency of 17.1%, showing long duration at the maximum power point tracking up to ~170 min. This low-cost organic network demonstrates a promising method for industry-scale fabrication of the organic/inorganic hybrid perovskite solar technology.",
        "keywords": [
            "Perovskite solar cells",
            "Suppressed hysteresis",
            "Stability",
            "Organic network",
            "PCBM/PEG"
        ],
        "authors": [
            {
                "name": "Jing Wei",
                "org": "Collaborative Innovation Center of Quantum Matter, 100084 Beijing, China;State Key Laboratory for Mesoscopic Physics and Electron Microscopy Laboratory, School of Physics, Peking University, 100871 Beijing, China;"
            },
            {
                "name": "Heng Li",
                "org": "Collaborative Innovation Center of Quantum Matter, 100084 Beijing, China;State Key Laboratory for Mesoscopic Physics and Electron Microscopy Laboratory, School of Physics, Peking University, 100871 Beijing, China;"
            },
            {
                "name": "Yicheng Zhao",
                "org": "Collaborative Innovation Center of Quantum Matter, 100084 Beijing, China;State Key Laboratory for Mesoscopic Physics and Electron Microscopy Laboratory, School of Physics, Peking University, 100871 Beijing, China;"
            },
            {
                "name": "Wenke Zhou",
                "org": "Collaborative Innovation Center of Quantum Matter, 100084 Beijing, China;State Key Laboratory for Mesoscopic Physics and Electron Microscopy Laboratory, School of Physics, Peking University, 100871 Beijing, China;"
            },
            {
                "name": "Rui Fu",
                "org": "Collaborative Innovation Center of Quantum Matter, 100084 Beijing, China;State Key Laboratory for Mesoscopic Physics and Electron Microscopy Laboratory, School of Physics, Peking University, 100871 Beijing, China;"
            },
            {
                "name": "Yamin Leprince-Wang",
                "org": "Universit\u00e9 Paris-Est, ESYCOM, UPEM, 5 bd. Descartes, F-77454 Marne-la-Vall\u00e9e, France;"
            },
            {
                "name": "Dapeng Yu",
                "org": "Collaborative Innovation Center of Quantum Matter, 100084 Beijing, China;State Key Laboratory for Mesoscopic Physics and Electron Microscopy Laboratory, School of Physics, Peking University, 100871 Beijing, China;"
            },
            {
                "name": "Qing Zhao",
                "org": "Collaborative Innovation Center of Quantum Matter, 100084 Beijing, China;State Key Laboratory for Mesoscopic Physics and Electron Microscopy Laboratory, School of Physics, Peking University, 100871 Beijing, China;"
            }
        ],
        "venue": "Nano Energy",
        "year": 2016
    },
    "4COqeGDo": {
        "id": "4COqeGDo",
        "title": "Flexible perovskite solar cells based on the metal-insulator-semiconductor structure.",
        "abstract": "The metal-insulator-semiconductor (MIS) structure is applied to perovskite solar cells, in which the traditional compact layer TiO2 is replaced by Al2O3 as the hole blocking material to realize an all-low-temperature process. Flexible devices based on this structure are also realized with excellent flexibility, which hold 85% of their initial efficiency after bending 100 times. ",
        "keywords": "",
        "authors": [
            {
                "name": "Jing Wei",
                "org": "State Key Laboratory for Mesoscopic Physics and Electron Microscopy Laboratory, School of Physics, Peking University, Beijing 100871, China. zhaoqing@pku.edu.cn."
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Yicheng Zhao",
                "org": ""
            },
            {
                "name": "Wenke Zhou",
                "org": ""
            },
            {
                "name": "Rui Fu",
                "org": ""
            },
            {
                "name": "Huiyue Pan",
                "org": ""
            },
            {
                "name": "Qing Zhao",
                "org": ""
            }
        ],
        "venue": "Chemical communications (Cambridge, England)",
        "year": 2016
    },
    "yY8PR9WX": {
        "id": "yY8PR9WX",
        "title": "Correlations between Immobilizing Ions and Suppressing Hysteresis in Perovskite Solar Cells",
        "abstract": "Ion migration has been regarded as the major cause of photocurrent hysteresis. Here we use photoluminescence (PL) and optical images, combined with Galvanostatic measurement, to detect the ionic motion. We observe an irreversible PL and optical transmittance change after electric poling. By comparing a neat perovskite film with the sample coated by poly(methyl methacrylate) (PMMA), polyethylene glycol (PEG), and [6,6]-phenyl-C61-butyric acid methyl ester (PCBM), we found that PCBM effectively inhibits ionic motion near the surface of the perovskite.We further evidenced the donor\u2013acceptor complex formed between PCBM and perovskite, implying the mechanism of inhibited ion migration by PCBM. We close by demonstrating that PCBM can also be introduced on the top of perovskite fim in an n\u2013i\u2013p TiO2 planar structure, to achieve an average 14% steady-state output over 2.3 \u00d7 105 s (\u223c64 h). This work highlights the importance of inhibiting ionic motion in perovskite solar cells.",
        "keywords": "",
        "authors": [
            {
                "name": "Yicheng Zhao",
                "org": ""
            },
            {
                "name": "Wenke Zhou",
                "org": ""
            },
            {
                "name": "Wei Ma",
                "org": ""
            },
            {
                "name": "Sheng Meng",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Jing Wei",
                "org": ""
            },
            {
                "name": "Rui Fu",
                "org": ""
            },
            {
                "name": "Kaihui Liu",
                "org": ""
            },
            {
                "name": "Dapeng Yu",
                "org": ""
            },
            {
                "name": "Qing Zhao",
                "org": ""
            }
        ],
        "venue": "ACS energy letters",
        "year": 2016
    },
    "dOCXlvZG": {
        "id": "dOCXlvZG",
        "title": "A study of hysteresis in perovskite solar cell",
        "abstract": "Hybrid lead-halide perovskite solar cells (PSCs) have become the hot spot in photovoltaic domain since 2012. Although perovskite solar cells exhibit high power conversion efficiencies (PCE), some unsolved issues remain in the measurement of device performance, especially the abnormal hysteresis in current-voltage scan. The hysteresis phenomena result in the overstatement of the performance of PSCs during backward scan, which starts from the bias higher than open voltage and sweep to voltage below zero. In steady output, the stabilised PCE is lower than the dynamic outcome, such as the maximum power point in the I-V curve. The origin of this abnormal hysteresis is under debate. Here, we introduced a model to explain the dependence of I-V measurements on scan history. According to computational simulations using semiconductor transport theories, we found that the experimental results were consistent with the model based on the polarisation of perovskite materials. The bias-induced polarisation affects both ...",
        "keywords": "",
        "authors": [
            {
                "name": "Qiaojing Yan",
                "org": ""
            },
            {
                "name": "Xianfeng Rui",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Dapeng Yu",
                "org": ""
            },
            {
                "name": "Qing Zhao",
                "org": ""
            }
        ],
        "venue": "International Journal of Nanomanufacturing",
        "year": 2016
    },
    "UK2QKpFq": {
        "id": "UK2QKpFq",
        "title": "Micro-scale hierarchical photoanode for quantum-dot-sensitized solar cells based on TiO2 nanowires",
        "abstract": "This paper proposed a new architecture design for nanowire-based quantum-dot-sensitized solar cells to improve the photovoltaic performance. Microstructured rough substrate was used to increase the surface area of the photoanode without influence on charge carrier transport in the system. Compared to conventional devices, the short circuit current density and power conversion efficiency were enhanced by 50%. And the technology can be widely used in the photoelectrochemical (PEC) field, and it can be combined with other hierarchical nanostructures.",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Wei Jing",
                "org": "Peking University"
            },
            {
                "name": "Dapeng Yu",
                "org": "Peking University"
            },
            {
                "name": "Qing Zhao",
                "org": "Peking University"
            }
        ],
        "venue": "Frontiers of Optoelectronics",
        "year": 2016
    },
    "sIUgmLnd": {
        "id": "sIUgmLnd",
        "title": "Nitrogen and phosphorus removal from anaerobically digested wastewater by microalgae cultured in a novel membrane photobioreactor.",
        "abstract": "In this study, a novel MPBR not only eliminated the inhibitory effects of suspended solid and microorganisms, but also maintained a high microalgae concentration to obtain a high amount of ammonia and phosphate removal. The research provided a theoretical foundation for the practical application of MPBRs in various wastewater treatment schemes without pretreatment by algae, which could be used as biofuels or protein feed.",
        "keywords": [
            "ADW",
            "Cultivations",
            "MPBR",
            "Membrane pore size",
            "Multi-batch",
            "Suspended solids"
        ],
        "authors": [
            {
                "name": "Xi Chen",
                "org": "1Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, The Key Lab for Synthetic Biotechnology of Xiamen City, Xiamen University, Xiamen, 361005 People's Republic of China."
            },
            {
                "name": "Zhipeng Li",
                "org": "1Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, The Key Lab for Synthetic Biotechnology of Xiamen City, Xiamen University, Xiamen, 361005 People's Republic of China."
            },
            {
                "name": "Ning He",
                "org": "1Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, The Key Lab for Synthetic Biotechnology of Xiamen City, Xiamen University, Xiamen, 361005 People's Republic of China."
            },
            {
                "name": "Yanmei Zheng",
                "org": "1Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, The Key Lab for Synthetic Biotechnology of Xiamen City, Xiamen University, Xiamen, 361005 People's Republic of China."
            },
            {
                "name": "Heng Li",
                "org": "1Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, The Key Lab for Synthetic Biotechnology of Xiamen City, Xiamen University, Xiamen, 361005 People's Republic of China."
            },
            {
                "name": "Haitao Wang",
                "org": "1Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, The Key Lab for Synthetic Biotechnology of Xiamen City, Xiamen University, Xiamen, 361005 People's Republic of China."
            },
            {
                "name": "Yuanpeng Wang",
                "org": "1Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, The Key Lab for Synthetic Biotechnology of Xiamen City, Xiamen University, Xiamen, 361005 People's Republic of China."
            },
            {
                "name": "Yinghua Lu",
                "org": "1Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, The Key Lab for Synthetic Biotechnology of Xiamen City, Xiamen University, Xiamen, 361005 People's Republic of China."
            },
            {
                "name": "Qingbiao Li",
                "org": "2College of Food and Biological Engineering, Jimei University, Xiamen, People's Republic of China."
            },
            {
                "name": "YaJuan Peng",
                "org": "1Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, The Key Lab for Synthetic Biotechnology of Xiamen City, Xiamen University, Xiamen, 361005 People's Republic of China."
            }
        ],
        "venue": "Biotechnology for biofuels",
        "year": 2018
    },
    "3laEMPln": {
        "id": "3laEMPln",
        "title": "Synthesis of short-chain-length and medium-chain-length polyhydroxyalkanoate blends from activated sludge by manipulating octanoic acid and nonanoic acid as carbon sources.",
        "abstract": "The effects of octanoic acid/nonanoic acid and acclimation time on the synthesis of short-chain-length and medium-chain-length PHA blends from activated sludge were investigated. An increased concentration (847~1366 mg/L) of PHAs was resulted from 4-month acclimation compared with the concentration derived from 2-month acclimation (450~1126 mg/L). The content of octanoic acid had a positive linear relationship with the content of even-numbered carbon monomers among the PHAs. The blending products were identified mainly with scl-PHAs during the 2-month acclimation period and were thereafter dominated by mcl-PHAs until 4 months of acclimation. Thermal properties analysis demonstrated that the products derived from 4-month acclimation were a mixture of scl-PHAs and mcl-PHAs rather than a copolymer of scl-PHAs and mcl-PHAs. High-throughput sequencing results indicated that Pseudofulvimonas, Paracoccus and Blastocatella were the dominant genera that might be responsible for scl-PHAs production during the 2-month acclimation period, whereas Comamonas and Pseudomonas that were responsible for mcl-PHAs production then became the dominant genera after 4-months acclimation.",
        "keywords": "",
        "authors": [
            {
                "name": "Zheng Chen",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361001, People\u2019s Republic of China"
            },
            {
                "name": "Chuanpan Zhang",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361001, People\u2019s Republic of China"
            },
            {
                "name": "Liang Shen",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": "Department of Environmental Science, School of Environmental Science and Engineering, Tan Kah Kee College, Xiamen University, Zhangzhou 363105, People\u2019s Republic of China"
            },
            {
                "name": "Yajuan Peng",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361001, People\u2019s Republic of China"
            },
            {
                "name": "Haitao Wang",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361001, People\u2019s Republic of China"
            },
            {
                "name": "Ning He",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361001, People\u2019s Republic of China"
            },
            {
                "name": "Qingbiao Li",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361001, People\u2019s Republic of China"
            },
            {
                "name": "Yuanpeng Wang",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361001, People\u2019s Republic of China"
            }
        ],
        "venue": "Journal of agricultural and food chemistry",
        "year": 2018
    },
    "iLOq22fI": {
        "id": "iLOq22fI",
        "title": "Nitrogen and phosphorus removal coupled with carbohydrate production by five microalgae cultures cultivated in biogas slurry.",
        "abstract": "In this study, five microalgae strains were cultured for their ability to survive in biogas slurry, remove nitrogen resources and accumulate carbohydrates. It was proved that five microalgae strains adapted in biogas slurry well without ammonia inhibition. Among them, Chlorella vulgaris ESP-6 showed the best performance on carbohydrate accumulation, giving the highest carbohydrate content of 61.5% in biogas slurry and the highest ammonia removal efficiency and rate of 96.3% and 91.7mg/L/d respectively in biogas slurry with phosphorus and magnesium added. Additionally, the absence of phosphorus and magnesium that can be adverse for biomass accumulation resulted in earlier timing of carbohydrate accumulation and magnesium was firstly recognized and proved as the influence factor for carbohydrate accumulation. Microalgae that cultured in biogas slurry accumulated more carbohydrate in cell, making biogas slurry more suitable medium for the improvement of carbohydrate content, thus can be regarded as a new strategy to accumulate carbohydrate.",
        "keywords": [
            "Ammonia nitrogen uptake",
            "Biogas slurry",
            "Carbohydrate accumulation",
            "Chlorella vulgaris"
        ],
        "authors": [
            {
                "name": "Fen Tan",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, The Key Lab for Synthetic Biotechnology of Xiamen City, Xiamen University, Xiamen 361005, PR China."
            },
            {
                "name": "Zhi Wang",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, The Key Lab for Synthetic Biotechnology of Xiamen City, Xiamen University, Xiamen 361005, PR China."
            },
            {
                "name": "Siyu Zhouyang",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, The Key Lab for Synthetic Biotechnology of Xiamen City, Xiamen University, Xiamen 361005, PR China."
            },
            {
                "name": "Heng Li",
                "org": "College of the Environment and Ecology, Xiamen University, Xiamen 361005, PR China."
            },
            {
                "name": "Youping Xie",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, The Key Lab for Synthetic Biotechnology of Xiamen City, Xiamen University, Xiamen 361005, PR China."
            },
            {
                "name": "Yuanpeng Wang",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, The Key Lab for Synthetic Biotechnology of Xiamen City, Xiamen University, Xiamen 361005, PR China."
            },
            {
                "name": "Yanmei Zheng",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, The Key Lab for Synthetic Biotechnology of Xiamen City, Xiamen University, Xiamen 361005, PR China."
            },
            {
                "name": "Qingbiao Li",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, The Key Lab for Synthetic Biotechnology of Xiamen City, Xiamen University, Xiamen 361005, PR China; College of the Environment and Ecology, Xiamen University, Xiamen 361005, PR China. Electronic address: kelqb@xmu.edu.cn."
            }
        ],
        "venue": "Bioresource technology",
        "year": 2016
    },
    "dqCYE3by": {
        "id": "dqCYE3by",
        "title": "Enhancement of digestates dewaterability by CTAB combined with CFA pretreatment",
        "abstract": "Abstract   In this study, the effects and mechanism of pretreating digestates with cetyltrimethylammonium bromide (CTAB) and coal fly ash (CFA) were investigated. The water content (WC) and specific resistance of filtration (SRF) of the digestates were measured to evaluate the digestate dewaterability. The protein (PN) content, polysaccharide (PS) content, zeta potential and particle size of the digestates were measured to probe the mechanism of pretreatment. The results indicated that the digestate dewatering performance was effectively improved by joint conditioning with CTAB and CFA. For straw digestate (St-digestate), pig manure digestate (PM-digestate), cow dung digestate (CD-digestate) and kitchen waste digestate (KW-digestate), the optimum dosage of CTAB was 50%, 30%, 20% and 50% dry solid (DS) of digestate, respectively, and the optimum dosage of CFA was 100% DS of digestate. Co-conditioning with CTAB and CFA resulted in clear advantages compared to CTAB or CFA conditioning alone for decreasing the WC of digestates. The proposed mechanism is the synergistic effect of CTAB and CFA. CTAB releases extracellular polymeric substances (EPS) and neutralizes charge, and CFA acts as a skeleton builder in the dewatering process to enhance dewaterability. Finally, a green degree method for the environmental assessment of chemical processes was adopted to evaluate digestate dewatering.",
        "keywords": "",
        "authors": [
            {
                "name": "Yangqing Zheng",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, PR China"
            },
            {
                "name": "Lanting Ke",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, PR China"
            },
            {
                "name": "Dong Xia",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, PR China"
            },
            {
                "name": "Yanmei Zheng",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, PR China"
            },
            {
                "name": "Yuanpeng Wang",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, PR China"
            },
            {
                "name": "Heng Li",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, PR China"
            },
            {
                "name": "Qingbiao Li",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, PR China"
            },
            {
                "name": "Qingbiao Li",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, PR China"
            }
        ],
        "venue": "Separation and Purification Technology",
        "year": 2016
    },
    "hHzhKLjL": {
        "id": "hHzhKLjL",
        "title": "ZnCl2-activated biochar from biogas residue facilitates aqueous As(III) removal",
        "abstract": "Abstract   Biochars prepared from biogas residue using different chemical activators were investigated for their As(III) adsorption properties. The results indicated that the original biochars did not exhibit significant As(III) adsorption. However, ZnCl 2 -activated biochar, which possessed the largest specific surface area, 516.67\u00a0cm 2 /g, and exhibited a perfectly porous texture, showed excellent performance in a 500\u00a0\u03bcgL \u22121  solution of As(III). Fourier transform infrared spectroscopy (FT-IR) and X-ray photoelectron spectroscopy were utilized to identify the mechanism of As(III) adsorption by ZnCl 2 -activated biochar. Adsorption was found to occur mainly through ligand exchange of the hydroxyl in Zn-OH to form Zn-O-As(III), as well as through porous adsorption. As a low-cost adsorbent, the adsorption process was well fitted using a pseudo-second-order model, with an R 2 \u00a0u003e\u00a00.993. The adsorption process was fast, requiring nearly 90\u00a0min to reach adsorption equilibrium. Batch adsorption experimental results indicated that ZnCl 2 -activated biochar has a maximum adsorption capacity of 27.67\u00a0mg/g at pH 7.0, and the adsorption process followed the Freundlich isotherm model well, with an R 2 \u00a0u003e\u00a00.994. In addition, the current work demonstrated the efficiency of using ZnCl 2 -activated biochar adsorbent to treat As(III)-contaminated water.",
        "keywords": "",
        "authors": [
            {
                "name": "Dong Xia",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, and The Key Laboratory for Synthetic Biotechnology of Xiamen City, Xiamen University, Xiamen 361005, PR China"
            },
            {
                "name": "Fen Tan",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, and The Key Laboratory for Synthetic Biotechnology of Xiamen City, Xiamen University, Xiamen 361005, PR China"
            },
            {
                "name": "Chuanpan Zhang",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, and The Key Laboratory for Synthetic Biotechnology of Xiamen City, Xiamen University, Xiamen 361005, PR China"
            },
            {
                "name": "Xiuli Jiang",
                "org": "Environmental Science Research Center, College of the Environment & Ecology, Xiamen University, Xiamen 361110, PR China"
            },
            {
                "name": "Zheng Chen",
                "org": "Environmental Science Research Center, College of the Environment & Ecology, Xiamen University, Xiamen 361110, PR China"
            },
            {
                "name": "Heng Li",
                "org": "Environmental Science Research Center, College of the Environment & Ecology, Xiamen University, Xiamen 361110, PR China"
            },
            {
                "name": "Yanmei Zheng",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, and The Key Laboratory for Synthetic Biotechnology of Xiamen City, Xiamen University, Xiamen 361005, PR China"
            },
            {
                "name": "Qingbiao Li",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, and The Key Laboratory for Synthetic Biotechnology of Xiamen City, Xiamen University, Xiamen 361005, PR China"
            },
            {
                "name": "Yuanpeng Wang",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, and The Key Laboratory for Synthetic Biotechnology of Xiamen City, Xiamen University, Xiamen 361005, PR China"
            }
        ],
        "venue": "Applied Surface Science",
        "year": 2016
    },
    "w4wVI1EC": {
        "id": "w4wVI1EC",
        "title": "Simulation research on anaerobic digestion biogas generation from low-grade biomass",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": "School of Chemistry and Life Science,Quanzhou Normal University"
            },
            {
                "name": "Lanting Ke",
                "org": ""
            },
            {
                "name": "Haitao Wang",
                "org": ""
            },
            {
                "name": "Yanmei Zheng",
                "org": ""
            },
            {
                "name": "Yuanpeng Wang",
                "org": ""
            },
            {
                "name": "Ning He",
                "org": ""
            },
            {
                "name": "Qingbiao Li",
                "org": ""
            },
            {
                "name": "\u674e\u6052",
                "org": ""
            },
            {
                "name": "\u738b\u6d77\u6d9b",
                "org": ""
            },
            {
                "name": "\u90d1\u8273\u6885",
                "org": ""
            },
            {
                "name": "\u738b\u8fdc\u9e4f",
                "org": ""
            },
            {
                "name": "\u4f55\u5b81",
                "org": ""
            },
            {
                "name": "\u674e\u6e05\u5f6a",
                "org": ""
            }
        ],
        "venue": "CIESC Journal",
        "year": 2014
    },
    "TjWRDVVM": {
        "id": "TjWRDVVM",
        "title": "Effectiveness and mechanisms of ammonium adsorption on biochars derived from biogas residues",
        "abstract": "The solid by-product of anaerobic digestion derived biochar has been used as an adsorbent for the liquid by-product and is a viable and environmental friendly way to control waste. In this study, two biochars (BC-PM, BC-ST) from pig manure biogas residue (BR-PM) and straw biogas residue (BR-ST) were assessed for ammonium adsorption. The ammonium adsorption on both BC-PM and BC-ST followed the Elovich kinetic model and fit well with the Langmuir isotherm, whereas BC-PM was better than BC-ST at absorbing ammonium. In addition, the adsorption mechanism was elucidated by analysing the physicochemical properties of the biochars. The Brunauer\u2013Emmett\u2013Teller (BET) surface area, pore structure and micromorphology, which are mainly related to the carbon in the biochars, had no direct correlation with the ammonium adsorption capacity. However, the ash in the biochars played an important role in ammonium adsorption. The metal elements in biochar ash significantly decreased after adsorption, especially potassium, which nearly disappeared as a result of ion exchange with ammonium. However, the quartz and carbonate mineral in biochar ash also functioned as ammonium adsorption sites according to Fourier transform infrared spectroscopy (FT-IR) and X-ray diffraction (XRD) analysis. This study revealed the irreplaceable role of ash in biochars for ammonium adsorption, which will guide the preparation of biochars from different types of feedstocks for ammonium adsorption.",
        "keywords": "",
        "authors": [
            {
                "name": "Qiangqiang Yu",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Xiamen University,Xiamen 361005,P. R. China"
            },
            {
                "name": "Qiangqiang Yu",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Xiamen University,Xiamen 361005,P. R. China"
            },
            {
                "name": "Dong Xia",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Xiamen University,Xiamen 361005,P. R. China"
            },
            {
                "name": "Heng Li",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Xiamen University,Xiamen 361005,P. R. China"
            },
            {
                "name": "Lanting Ke",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Xiamen University,Xiamen 361005,P. R. China"
            },
            {
                "name": "Yuanpeng Wang",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Xiamen University,Xiamen 361005,P. R. China"
            },
            {
                "name": "Haitao Wang",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Xiamen University,Xiamen 361005,P. R. China"
            },
            {
                "name": "Yanmei Zheng",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Xiamen University,Xiamen 361005,P. R. China"
            },
            {
                "name": "Qingbiao Li",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Xiamen University,Xiamen 361005,P. R. China"
            },
            {
                "name": "Qingbiao Li",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Xiamen University,Xiamen 361005,P. R. China"
            }
        ],
        "venue": "RSC Advances",
        "year": 2016
    },
    "oVA6ukL0": {
        "id": "oVA6ukL0",
        "title": "Estimating the Fates of C and N in Various Anaerobic Codigestions of Manure and Lignocellulosic Biomass Based on Artificial Neural Networks",
        "abstract": "In this study, artificial-neural-network- (ANN-) based models were explored and validated to predict the fates of carbon (C) and nitrogen (N) under 84 types of digesters in treating different blends of seven substrates (corn straw, rice straw, wheat straw, swine manure with fed feedstuff and foodstuff, cattle manure, and chicken manure) under changing volatile solids (VS) loadings. ANN models based on principal component analysis (PC-ANN) were developed for estimating the fate of C (CH4 yields and COD concentrations in the supernatant), showing higher prediction accuracies than the original ANN models. The fate of N (NH4+-N concentrations in the supernatant) was well predicted by the ANN model with two inputs, namely, total Kjeldahl nitrogen (TKN) and total ammonium nitrogen (TAN) in the substrates. The models were also developed for wide applications to validate the CH4 yields and NH4+-N concentrations for new databases outside the established data range obtained from the literature, with regression coef...",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Lanting Ke",
                "org": ""
            },
            {
                "name": "Zheng Chen",
                "org": ""
            },
            {
                "name": "Guangjing Feng",
                "org": ""
            },
            {
                "name": "Dong Xia",
                "org": ""
            },
            {
                "name": "Yuanpeng Wang",
                "org": ""
            },
            {
                "name": "Yanmei Zheng",
                "org": ""
            },
            {
                "name": "Qingbiao Li",
                "org": ""
            }
        ],
        "venue": "Energy & Fuels",
        "year": 2016
    },
    "FoviEUbi": {
        "id": "FoviEUbi",
        "title": "Performance, granule conductivity and microbial community analysis of upflow anaerobic sludge blanket (UASB) reactors from mesophilic to thermophilic operation",
        "abstract": "Abstract   Effects of temperature variations from mesophilic to thermophilic on the performance of UASB reactors with glucose and ethanol as substrate were investigated. The reactor with ethanol as substrate had better resistance to temperature variations with over 93% COD degradation rate and 75% methane content. The conductivity of granular sludge that degraded ethanol was also considerably higher. High-throughput sequencing indicated that the abundance of  Methanobacterium  decreased, while  Methanosaeta  increased with increasing temperature. Moreover, the abundance of  Geobacter  and  Methanosaeta  were higher in the reactor with ethanol as substrate than that with glucose, whereas a higher abundance of  Klebsiella  was observed in the glucose reactor. More importantly, significant correlations were observed between granular sludge conductivity and COD removal rate (R 2 \u202f=\u202f0.73), between the abundance of  Geobacter  and COD removal rate (R 2 \u202f=\u202f0.895). These results indicate that the growth of  Geobacter  and  Methanosaeta  which promote transfer electrons in the manner of DIET in anaerobic methanogenic systems might alleviate the effect of temperature variation and facilitate reaction rate.",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, PR China"
            },
            {
                "name": "Kezeng Han",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, PR China"
            },
            {
                "name": "Zhipeng Li",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, PR China"
            },
            {
                "name": "Jinfeng Zhang",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, PR China"
            },
            {
                "name": "Hua Li",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, PR China"
            },
            {
                "name": "Yaohua Huang",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, PR China"
            },
            {
                "name": "Liang Shen",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, PR China"
            },
            {
                "name": "Qingbiao Li",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, PR China"
            },
            {
                "name": "Qingbiao Li",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, PR China"
            },
            {
                "name": "Yuanpeng Wang",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, PR China"
            }
        ],
        "venue": "Biochemical Engineering Journal",
        "year": 2018
    },
    "lLx7kWRp": {
        "id": "lLx7kWRp",
        "title": "Addition of graphene sheets enhances reductive dissolution of arsenic and iron from arsenic contaminated soil",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Zheng Chen",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical \u202cEngineering; Xiamen University; Xiamen 361005 P. R. China"
            },
            {
                "name": "Zheng Chen",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical \u202cEngineering; Xiamen University; Xiamen 361005 P. R. China"
            },
            {
                "name": "Heng Li",
                "org": "Key Laboratory of Estuarine Ecological Security and Environmental Health, Tan Kah Kee College; Xiamen University; Zhangzhou 363105 P. R. China"
            },
            {
                "name": "Wende Ma",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical \u202cEngineering; Xiamen University; Xiamen 361005 P. R. China"
            },
            {
                "name": "Dun Fu",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical \u202cEngineering; Xiamen University; Xiamen 361005 P. R. China"
            },
            {
                "name": "Kezeng Han",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical \u202cEngineering; Xiamen University; Xiamen 361005 P. R. China"
            },
            {
                "name": "Haitao Wang",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical \u202cEngineering; Xiamen University; Xiamen 361005 P. R. China"
            },
            {
                "name": "Ning He",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical \u202cEngineering; Xiamen University; Xiamen 361005 P. R. China"
            },
            {
                "name": "Qingbiao Li",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical \u202cEngineering; Xiamen University; Xiamen 361005 P. R. China"
            },
            {
                "name": "Yuanpeng Wang",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical \u202cEngineering; Xiamen University; Xiamen 361005 P. R. China"
            }
        ],
        "venue": "Land Degradation & Development",
        "year": 2018
    },
    "BspmI7vr": {
        "id": "BspmI7vr",
        "title": "Applicability of HDPC-supported Cu nanoparticles composite synthesized from anaerobically digested wheat straw for octocrylene degradation in aqueous solutions",
        "abstract": "Abstract   The technical applicability of hydrochar-derived pyrolysis char-supported Cu nanoparticles composite (Cu NPs/HDPC) to the degradation of octocrylene (OC) was investigated in aqueous solutions in the presence of H 2 O 2 . The physico-chemical properties of the Cu NPs/HDPC composite before and after degradation reaction were described. The role of  OH in this H 2 O 2 -led degradation was examined using electron spin resonance (EPR) technique. The possible degradation mechanisms of OC by the Cu NPs/HDPC-H 2 O 2  system and its degradation pathways were investigated. A relatively large surface area and pore volume of the HDPC (191.4\u202fm 2 \u202fg \u22121  and 0.11\u202fcm 3 \u202fg \u22121 , respectively) resulted in well-dispersed Cu NPs loading on the surface. The degradation efficiency of OC (50\u202f\u03bcM) was 97.0% in the presence of Cu NPs/HDPC composite (0.5\u202fg\u202fL \u22121 ) and H 2 O 2  (20\u202fmM) at pH 5.6 in 4\u202fh, which was significantly higher than in Cu NPs/biochar and the integrated HDPC-Cu NPs, i.e., 62.4% and 79.7%, respectively, under the same conditions (ANOVA test;  p \u202f\u2264\u202f0.05). Several oxidation by-products of the OC included benzophenone, 3,3-diphenylacrylonitrile, and others. The  OH, which resulted from the Fenton-like oxidation between the Cu species and H 2 O 2  on the HDPC surface, was the predominant factor responsible for the OC degradation in the solution. The  OH formation was facilitated by a single-electron transfer process from the HDPC surface, in which the Cu NPs/HDPC composite with its C OH functional group promoted the decomposition of H 2 O 2 . These findings contribute to a novel approach of cost-effective wastewater treatment by adding value to unused waste materials from agricultural industries.",
        "keywords": "",
        "authors": [
            {
                "name": "Dun Fu",
                "org": "Department of Ecological Engineering for Environmental Sustainability, College of the Environment & Ecology, Xiamen University, Xiamen 361102, PR China"
            },
            {
                "name": "Tonni Agustiono Kurniawan",
                "org": "Department of Ecological Engineering for Environmental Sustainability, College of the Environment & Ecology, Xiamen University, Xiamen 361102, PR China"
            },
            {
                "name": "Heng Li",
                "org": "Department of Environmental Science and Engineering, Tan Kah Kee College, Xiamen University, Zhangzhou 363105, PR China"
            },
            {
                "name": "Liuying Wang",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, and The Key Laboratory for Synthetic Biotechnology of Xiamen City, Xiamen University, Xiamen 361005, PR China"
            },
            {
                "name": "Zheng Chen",
                "org": "Department of Environmental Science and Engineering, Tan Kah Kee College, Xiamen University, Zhangzhou 363105, PR China"
            },
            {
                "name": "Wen Li",
                "org": "Department of Ecological Engineering for Environmental Sustainability, College of the Environment & Ecology, Xiamen University, Xiamen 361102, PR China"
            },
            {
                "name": "Yuanpeng Wang",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, and The Key Laboratory for Synthetic Biotechnology of Xiamen City, Xiamen University, Xiamen 361005, PR China"
            },
            {
                "name": "Haitao Wang",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, and The Key Laboratory for Synthetic Biotechnology of Xiamen City, Xiamen University, Xiamen 361005, PR China"
            },
            {
                "name": "Qingbiao Li",
                "org": "Department of Ecological Engineering for Environmental Sustainability, College of the Environment & Ecology, Xiamen University, Xiamen 361102, PR China"
            }
        ],
        "venue": "Chemical Engineering Journal",
        "year": 2019
    },
    "GQSyRbxX": {
        "id": "GQSyRbxX",
        "title": "Production of polyhydroxyalkanoates by activated sludge: Correlation with extracellular polymeric substances and characteristics of activated sludge",
        "abstract": "Abstract   To understand PHAs accumulation process well in the stand point of the sludge characteristics, polyhydroxyalkanoates (PHAs) accumulation by activated sludge was investigated in correlation with sludge properties, such as particle size, mixed liquor suspended solids (MLSS) and extracellular polymeric substances (EPS) under different carbon sources (e.g., acetate, propionate and mixed carbons) at 2, 4, 6 and 8\u202fg/L. The efficiency of PHAs synthesis from sludge with sodium acetate as carbon source was superior to that with sodium propionate as carbon source and mixed carbon sources in the sequencing biological reactors, while EPS and sludge characteristics showed similar trends for each carbon source. Various carbon sources did not induce significant differences in the correlations. Polyhydroxybutyrate (PHB) showed good correlation with MLSS (R\u202f=\u202f0.782) and sludge floc size (R\u202f=\u202f\u22120.58). In the reactors with carbon sources of propionate and mixed carbons, polyhydroxyvalerate (PHV) and PHBV correlated with MLSS (R\u202f=\u202f0.480 and 0.489, respectively), sludge floc size (R\u202f=\u202f\u22120.921 and \u22120.666, respectively) and concentrations of polysaccharides (R\u202f=\u202f0.726, 0.557, respectively). According to the correlations, improving the concentration of sludge, promoting the production of extracellular polymeric substances (EPS) and decreasing the sludge floc size were supposed to be effective approaches for further accumulation of the PHAs. This study is the first to systematically establish the correlations among EPS, characteristics of activated sludge and PHAs accumulation, can provide a theoretical foundation for the engineering design and the operational parameters selection of PHAs production by activated sludge.",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, PR China"
            },
            {
                "name": "Jinfeng Zhang",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, PR China"
            },
            {
                "name": "Liang Shen",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, PR China"
            },
            {
                "name": "Zheng Chen",
                "org": "Key Laboratory of Estuarine Ecological Security and Environmental Health, Tan Kah Kee College, Xiamen University, Zhangzhou, PR China"
            },
            {
                "name": "Yanan Zhang",
                "org": "Key Laboratory of Estuarine Ecological Security and Environmental Health, Tan Kah Kee College, Xiamen University, Zhangzhou, PR China"
            },
            {
                "name": "Chuanpan Zhang",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, PR China"
            },
            {
                "name": "Qingbiao Li",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, PR China"
            },
            {
                "name": "Yuanpeng Wang",
                "org": "Department of Chemical and Biochemical Engineering, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, PR China"
            }
        ],
        "venue": "Chemical Engineering Journal",
        "year": 2019
    },
    "8WK4ezAP": {
        "id": "8WK4ezAP",
        "title": "Quaternion generic Fourier descriptor for color object recognition.",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Zhiwen Liu",
                "org": ""
            },
            {
                "name": "Yali Huang",
                "org": ""
            },
            {
                "name": "Yonggang Shi",
                "org": ""
            }
        ],
        "venue": "Pattern Recognition",
        "year": 2015
    },
    "aAbgtejN": {
        "id": "aAbgtejN",
        "title": "Analyzing dynamic cellular morphology in time-lapsed images enabled by cellular deformation pattern recognition.",
        "abstract": "Computational analysis of cellular morphology aims to provide quantitative information of the global organizational and physiological state of cells, and has long been a major topic of biomedical research. Instead of analyzing morphology of static cells, we concentrate on live-cell deformation in a period of time. According to our observation of dynamic cell behavior, we have assumed that the pattern of cellular deformation is relevant to the cellular state. Moreover, based on our assumption an innovative approach for characterizing the deformation pattern is described and applied into cell classification. After normalizing and aligning cell image sequences, we extract the continuity of deformation at each angle through time-lapse. Then the deformation pattern is given by the histogram of the continuity of deformation. Experimental results demonstrate that the cellular deformation pattern provided by our approach can be applied to discriminate cellular activation. In addition, the deformation pattern recognition makes remarkable progress in the classification of cells.",
        "keywords": [],
        "authors": [
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Zhiwen Liu",
                "org": ""
            },
            {
                "name": "Fengqian Pang",
                "org": ""
            },
            {
                "name": "Zhiyi Fan",
                "org": ""
            },
            {
                "name": "Yonggang Shi",
                "org": ""
            }
        ],
        "venue": "EMBC",
        "year": 2015
    },
    "zZH0IAcz": {
        "id": "zZH0IAcz",
        "title": "The measurement of cell viability based on temporal bag of words for image sequences.",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Fengqian Pang",
                "org": ""
            },
            {
                "name": "Zhiwen Liu",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Yonggang Shi",
                "org": ""
            }
        ],
        "venue": "ICIP",
        "year": 2015
    },
    "dFqYepMM": {
        "id": "dFqYepMM",
        "title": "Characterization of single cell dynamic morphology by local deformation pattern modeling.",
        "abstract": "Computational analysis of cell dynamic morphology in time-lapse images has become a new topic of biomedical research. For single cell, it is a challenging task to consider the spatial inconsistency and the temporal accumulation of cell deformation. This paper introduces an innovative automate analysis method, in which temporal features of contour point deformation are captured and then local deformation pattern is modeled to characterize cell dynamic morphology and predict cell activation statue. We applied the method to classify lymphocyte videos of multiple groups. Experimental results demonstrate that the proposed method overcomes existing methods in accuracy and robustness.",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Zhiwen Liu",
                "org": ""
            },
            {
                "name": "Fengqian Pang",
                "org": ""
            },
            {
                "name": "Yonggang Shi",
                "org": ""
            }
        ],
        "venue": "EMBC",
        "year": 2017
    },
    "HHiNn9J3": {
        "id": "HHiNn9J3",
        "title": "Cell dynamic morphology analysis by deep convolutional features.",
        "abstract": "Computational analysis of cell dynamic morphology in time-lapse image is a challenging task in biomedical research. Inspired by the recent success of deep learning, we investigate the possibility to apply a deep neural network to cell dynamic morphology analysis in this paper. Specifically, a contour spectrum is composed as the input of neural network to characterize cell spatiotemporal deformation, then a pre-trained convolutional neural network model is performed for automatic feature extraction. Finally, the extracted deep convolutional features are analyzed by SVM. Experimental results demonstrate that the proposed strategy outperforms existing methods on the live-cell database, and the features extracted by the last layer and classified by linear kernel SVM allows for the state-of-the-art performance.",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": "School of Information and Electronics, Beijing Institute of Technology, China"
            },
            {
                "name": "Zhiwen Liu",
                "org": "School of Information and Electronics, Beijing Institute of Technology, China"
            },
            {
                "name": "Fengqian Pang",
                "org": "School of Information and Electronics, Beijing Institute of Technology, China"
            },
            {
                "name": "Yonggang Shi",
                "org": "School of Information and Electronics, Beijing Institute of Technology, China"
            }
        ],
        "venue": "EMBC",
        "year": 2017
    },
    "5EZHtOwl": {
        "id": "5EZHtOwl",
        "title": "Computational Analysis of Cell Dynamics in Videos with Hierarchical-Pooled Deep-Convolutional Features.",
        "abstract": "Computational analysis of cellular appearance and its dynamics is used to investigate physiological properties of cells in biomedical research. In consideration of the great success of deep learning in video analysis, we first introduce two-stream convolutional networks (ConvNets) to automatically learn the biologically meaningful dynamics from raw live-cell videos. However, the two-stream ConvNets lack the ability to capture long-range video evolution. Therefore, a novel hierarchical pooling strategy is proposed to model the cell dynamics in a whole video, which is composed of trajectory pooling for short-term dynamics and rank pooling for long-range ones. Experimental results demonstrate that the proposed pipeline effectively captures the spatiotemporal dynamics from the raw live-cell videos and outperforms existing methods on our cell video database.",
        "keywords": [
            "cell dynamics",
            "deep convolutional features",
            "deep convolutional networks",
            "hierarchical pooling"
        ],
        "authors": [
            {
                "name": "Fengqian Pang",
                "org": "Department of Information and Electronics, Beijing Institute of Technology , Beijing, China ."
            },
            {
                "name": "Heng Li",
                "org": "Department of Information and Electronics, Beijing Institute of Technology , Beijing, China ."
            },
            {
                "name": "Yonggang Shi",
                "org": "Department of Information and Electronics, Beijing Institute of Technology , Beijing, China ."
            },
            {
                "name": "Zhiwen Liu",
                "org": "Department of Information and Electronics, Beijing Institute of Technology , Beijing, China ."
            }
        ],
        "venue": "Journal of computational biology : a journal of computational molecular cell biology",
        "year": 2018
    },
    "PgQcrEIj": {
        "id": "PgQcrEIj",
        "title": "Cell dynamic morphology classification using deep convolutional neural networks.",
        "abstract": "Cell morphology is often used as a proxy measurement of cell status to understand cell physiology. Hence, interpretation of cell dynamic morphology is a meaningful task in biomedical research. Inspired by the recent success of deep learning, we here explore the application of convolutional neural networks (CNNs) to cell dynamic morphology classification. An innovative strategy for the implementation of CNNs is introduced in this study. Mouse lymphocytes were collected to observe the dynamic morphology, and two datasets were thus set up to investigate the performances of CNNs. Considering the installation of deep learning, the classification problem was simplified from video data to image data, and was then solved by CNNs in a self-taught manner with the generated image data. CNNs were separately performed in three installation scenarios and compared with existing methods. Experimental results demonstrated the potential of CNNs in cell dynamic morphology classification, and validated the effectiveness of the proposed strategy. CNNs were successfully applied to the classification problem, and outperformed the existing methods in the classification accuracy. For the installation of CNNs, transfer learning was proved to be a promising scheme. \u00a9 2018 International Society for Advancement of Cytometry.",
        "keywords": [
            "cell dynamic morphology",
            "cell status prediction",
            "convolutional neural networks",
            "deep learning",
            "transfer learning"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": "School of Information and Electronics, Beijing Institute of Technology, Beijing 100081, China."
            },
            {
                "name": "Fengqian Pang",
                "org": "School of Information and Electronics, Beijing Institute of Technology, Beijing 100081, China."
            },
            {
                "name": "Yonggang Shi",
                "org": "School of Information and Electronics, Beijing Institute of Technology, Beijing 100081, China."
            },
            {
                "name": "Zhiwen Liu",
                "org": "School of Information and Electronics, Beijing Institute of Technology, Beijing 100081, China."
            }
        ],
        "venue": "Cytometry. Part A : the journal of the International Society for Analytical Cytology",
        "year": 2018
    },
    "ngujAEMQ": {
        "id": "ngujAEMQ",
        "title": "Cell dynamic morphology classification using deep convolutional neural networks: Cell Dynamic Morphology",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": "School of Information and ElectronicsBeijing Institute of TechnologyBeijing 100081 China"
            },
            {
                "name": "Fengqian Pang",
                "org": "School of Information and ElectronicsBeijing Institute of TechnologyBeijing 100081 China"
            },
            {
                "name": "Yonggang Shi",
                "org": "School of Information and ElectronicsBeijing Institute of TechnologyBeijing 100081 China"
            },
            {
                "name": "Zhiwen Liu",
                "org": "School of Information and ElectronicsBeijing Institute of TechnologyBeijing 100081 China"
            }
        ],
        "venue": "Cytometry Part A",
        "year": 2018
    },
    "3PyG9lGZ": {
        "id": "3PyG9lGZ",
        "title": "Characterization of single cell dynamic morphology by local deformation pattern modeling.",
        "abstract": "Computational analysis of cell dynamic morphology in time-lapse images has become a new topic of biomedical research. For single cell, it is a challenging task to consider the spatial inconsistency and the temporal accumulation of cell deformation. This paper introduces an innovative automate analysis method, in which temporal features of contour point deformation are captured and then local deformation pattern is modeled to characterize cell dynamic morphology and predict cell activation statue. We applied the method to classify lymphocyte videos of multiple groups. Experimental results demonstrate that the proposed method overcomes existing methods in accuracy and robustness.",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": "School of Information and Electronics, Beijing Institute of Technology, China"
            },
            {
                "name": "Zhiwen Liu",
                "org": "School of Information and Electronics, Beijing Institute of Technology, China"
            },
            {
                "name": "Fengqian Pang",
                "org": "School of Information and Electronics, Beijing Institute of Technology, China"
            },
            {
                "name": "Yonggang Shi",
                "org": "School of Information and Electronics, Beijing Institute of Technology, China"
            }
        ],
        "venue": "EMBC",
        "year": 2017
    },
    "vSlVKH9e": {
        "id": "vSlVKH9e",
        "title": "A real-time image optimization strategy based on global saliency detection for artificial retinal prostheses.",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Tingting Han",
                "org": ""
            },
            {
                "name": "Jing Wang",
                "org": ""
            },
            {
                "name": "Zhuofan Lu",
                "org": ""
            },
            {
                "name": "Xiaofei Cao",
                "org": ""
            },
            {
                "name": "Yao Chen",
                "org": ""
            },
            {
                "name": "Liming Li",
                "org": ""
            },
            {
                "name": "Chuanqing Zhou",
                "org": ""
            },
            {
                "name": "Xinyu Chai",
                "org": ""
            }
        ],
        "venue": "Inf. Sci.",
        "year": 2017
    },
    "QurUms3m": {
        "id": "QurUms3m",
        "title": "Eye-hand coordination using two irregular phosphene maps in simulated prosthetic vision for retinal prostheses.",
        "abstract": "Clinical trials have shown different irregular characteristics of phosphene maps can be elicited by retinal prostheses. This study investigated the effect of distortion and dropout percentage on two novel eye-hand coordination tasks. 16 volunteers participated in two tasks on a touch screen: drawing geometric shapes and writing Chinese characters. The accuracy and efficiency in both tasks were recorded and compared while one irregular characteristic was changed. Results show that the accuracy and efficiency of both tasks decrease as the variability of distortion and dropout percentage increase, which may provide theoretical and practical significance for the clinical research on retinal prostheses.",
        "keywords": "",
        "authors": [
            {
                "name": "Xiaofei Cao",
                "org": "School of Biomedical Engineering Shanghai Jiao Tong University Shanghai, China"
            },
            {
                "name": "Heng Li",
                "org": "School of Biomedical Engineering Shanghai Jiao Tong University Shanghai, China"
            },
            {
                "name": "Zhuofan Lu",
                "org": "School of Biomedical Engineering Shanghai Jiao Tong University Shanghai, China"
            },
            {
                "name": "Xinyu Chai",
                "org": "School of Biomedical Engineering Shanghai Jiao Tong University Shanghai, China"
            },
            {
                "name": "Jing Wang",
                "org": "College of Information Technology Shanghai Ocean University Shanghai, China"
            }
        ],
        "venue": "CISP-BMEI",
        "year": 2017
    },
    "kzBaaT7v": {
        "id": "kzBaaT7v",
        "title": "Comparison of cortical responses to the activation of retina by visual stimulation and transcorneal electrical stimulation.",
        "abstract": "According to our results, we provided some evidence that the cortical processing of TES was influenced by the distribution of the electrical field in the retina and the activating threshold of different retinal ganglion cells.",
        "keywords": [
            "Cortical response",
            "Optical imaging of intrinsic signals",
            "Retinal electrical stimulation",
            "Visual stimulation"
        ],
        "authors": [
            {
                "name": "Pengcheng Sun",
                "org": "School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China."
            },
            {
                "name": "Heng Li",
                "org": "School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China."
            },
            {
                "name": "Zhuofan Lu",
                "org": "School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China."
            },
            {
                "name": "Xiaofan Su",
                "org": "School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China."
            },
            {
                "name": "Zengguang Ma",
                "org": "School of Biomedical Engineering and Technology, Tianjin Medical University, Tianjin 300070, China."
            },
            {
                "name": "Jianpin Chen",
                "org": "School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China."
            },
            {
                "name": "Liming Li",
                "org": "School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China."
            },
            {
                "name": "Chuanqing Zhou",
                "org": "School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China."
            },
            {
                "name": "Yao Chen",
                "org": "School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China. Electronic address: yao.chen@sjtu.edu.cn."
            },
            {
                "name": "Xinyu Chai",
                "org": "School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China. Electronic address: xychai@sjtu.edu.cn."
            }
        ],
        "venue": "Brain stimulation",
        "year": 2018
    },
    "Pzfd4VpB": {
        "id": "Pzfd4VpB",
        "title": "Eddy-current-induced distortion correction using maximum reconciled mutual information in diffusion MR imaging.",
        "abstract": "The results suggest that there is a high-level matching in space between the b0 image and the DW images aligned by the MRMI method, raising the registration robustness and accuracy compared to the traditional DW registration methods. It may provide a better option for the existing diffusion image registration tools (e.g., FMRIB Software Library) and commonly multimodal medical image registration.",
        "keywords": [
            "Diffusion MR",
            "Diffusion-weighted imaging",
            "Mutual information",
            "Reconcile entropy",
            "Registration"
        ],
        "authors": [
            {
                "name": "Junling Liang",
                "org": "School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China."
            },
            {
                "name": "Shujun Zhao",
                "org": "College of Physical Engineering, Zhengzhou University, Zhengzhou, 450001, China."
            },
            {
                "name": "Liqing Di",
                "org": "School of Medicine, Shanghai Jiao Tong University, Shanghai, 200240, China."
            },
            {
                "name": "Jingjuan Wang",
                "org": "Xuanwu Hospital of Capital Medical University, Beijing, 100053, China."
            },
            {
                "name": "Pengcheng Sun",
                "org": "School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China."
            },
            {
                "name": "Xinyu Chai",
                "org": "School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China. xychai@sjtu.edu.cn."
            },
            {
                "name": "Heng Li",
                "org": "School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China. liheng@sjtu.edu.cn."
            }
        ],
        "venue": "International journal of computer assisted radiology and surgery",
        "year": 2019
    },
    "x1JXIv5S": {
        "id": "x1JXIv5S",
        "title": "Perceived visual field expanding with content-aware image retargeting for prosthetic vision",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Xinyu Chai",
                "org": "Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China"
            },
            {
                "name": "Yajie Zeng",
                "org": "Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China"
            },
            {
                "name": "Heng Li",
                "org": "Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China"
            },
            {
                "name": "Yao Chen",
                "org": "Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China"
            },
            {
                "name": "Chuanqing Zhou",
                "org": "Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China"
            }
        ],
        "venue": "Investigative Ophthalmology & Visual Science",
        "year": 2017
    },
    "2ajk8WTv": {
        "id": "2ajk8WTv",
        "title": "A real-time image optimization strategy based on global saliency detection for artificial retinal prostheses.",
        "abstract": "Abstract   Current retinal prostheses can only generate low-resolution visual percepts constituted of inadequate phosphenes which are elicited by a limited number of stimulating electrodes and with unruly color and restricted grayscale. Fortunately, for most retinal prostheses, an external camera and a video processing unit are employed to be essential components, and allow image processing to improve visual perception for recipients. At present, there have been some studies that use a variety of sophisticated image processing algorithms to improve prosthetic vision perception. However, most of them cannot achieve real-time processing due to the complexity of the algorithms and the limitation of platform processing power. This greatly curbs the practical application of these algorithms on the retinal prostheses. In this study, we propose a real-time image processing strategy based on a novel bottom-up saliency detection algorithm, aiming to detect and enhance foreground objects in a scene. Results demonstrate by verification of conducting two eye-hand-coordination visual tasks that under simulated prosthetic vision, our proposed strategy has noticeable advantages in terms of accuracy, efficiency, and head motion range. The study aims to help develop image processing modules in retinal prostheses, and is hoped to provide more benefit towards prosthesis recipients.",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": "School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China"
            },
            {
                "name": "Tingting Han",
                "org": "School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China"
            },
            {
                "name": "Jing Wang",
                "org": "College of Information Technology, Shanghai Ocean University, Shanghai 201306, China"
            },
            {
                "name": "Zhuofan Lu",
                "org": "School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China"
            },
            {
                "name": "Xiaofei Cao",
                "org": "School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China"
            },
            {
                "name": "Yao Chen",
                "org": "School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China"
            },
            {
                "name": "Liming Li",
                "org": "School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China"
            },
            {
                "name": "Chuanqing Zhou",
                "org": "School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China"
            },
            {
                "name": "Xinyu Chai",
                "org": "School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China"
            }
        ],
        "venue": "Inf. Sci.",
        "year": 2017
    },
    "VE10O6Dx": {
        "id": "VE10O6Dx",
        "title": "Depth-resolved physiological response of retina to transcorneal electrical stimulation measured with optical coherence tomography.",
        "abstract": "Transcorneal electrical stimulation (TES) has become an effective strategy to modulate retinal neural activities and partially restore visual function in ophthalmic diseases. However, the exact responses in different retinal layers still need to be clarified. This study's goal was to evaluate the depth-resolved retinal physiological responses evoked by TES by using optical coherence tomography (OCT). A custom-built spectral-domain OCT system was used to record the intrinsic optical signals (IOSs) in different retinal layers. TES and flickers were used to stimulate the retina electrically and visually. Tetrodotoxin was used to inhibit the retinal neural activity for confirming the origin of TES-induced IOSs. We found both positive and negative IOSs could be evoked by TES in three segmented retinal layers, especially in the inner retina and subretinal space. The TES-induced IOSs correlated with the TES intensity. After tetrodotoxin injection, the IOSs evoked by TES was significantly declined, peculiarly in the inner retina. The IOSs elicited by flickers kept increasing during the stimulation, while those evoked by TES kept at a stable level. In conclusion, TES could elicit IOSs that originated from retinal neural activity in all segmented layers. The TES-induced IOSs were highly synchronized to the electrical field in the retina.",
        "keywords": "",
        "authors": [
            {
                "name": "Pengcheng Sun",
                "org": ""
            },
            {
                "name": "Qian Li",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Liqing Di",
                "org": ""
            },
            {
                "name": "Xiaofan Su",
                "org": ""
            },
            {
                "name": "Jianpin Chen",
                "org": ""
            },
            {
                "name": "Hao Zheng",
                "org": ""
            },
            {
                "name": "Yao Chen",
                "org": ""
            },
            {
                "name": "Chuanqing Zhou",
                "org": ""
            },
            {
                "name": "Xinyu Chai",
                "org": ""
            }
        ],
        "venue": "IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society",
        "year": 2019
    },
    "JW9S5UG6": {
        "id": "JW9S5UG6",
        "title": "Research on the Electrodermal Activity during Walking and Running",
        "abstract": "Electrodermal activity (EDA), referred to the term for changes in electrical conductance of the skin, is a significant physiological signals in health. It can be applied to many aspects, such as affective computing and the monitoring of diseases. Physical activity signal is another kind of commonly used parameter. However, body movement has great influence on physiological signals because of the changes in autonomic sympathetic arousal caused by energy expenditure. It is difficult for the recognition of emotion and the record of physiological signals associated with disease. There are few related researches during normal daily activity, especially in motion states. In the present study, we developed a wrist-type multi-physiological parameters acquisition device, recording EDA, skin temperature, acceleration and angular velocity signals, to study the variation of physiological signals in motion states, like walking and running. We found that the EDA was positively correlated with energy expenditure under different physical motion states. The more intense the movement is, the faster the EDA changes and vice versa. The result of this study could be used to facilitate the application of affective computing during motion states, and further be used in emotional recognition of athletes or normal people during daily exercise in the future.",
        "keywords": [
            "Skin",
            "Task analysis",
            "Temperature measurement",
            "Acceleration",
            "Legged locomotion",
            "Biomedical monitoring",
            "Angular velocity"
        ],
        "authors": [
            {
                "name": "Xiaoyong Ji",
                "org": "School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China"
            },
            {
                "name": "Heng Li",
                "org": "School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China"
            },
            {
                "name": "Zhuofan Lu",
                "org": "School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China"
            },
            {
                "name": "Zifeng Wang",
                "org": "School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China"
            },
            {
                "name": "Xinyu Chai",
                "org": "School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China"
            }
        ],
        "venue": "2019 4th International Conference on Control and Robotics Engineering (ICCRE)",
        "year": 2019
    },
    "wSTrtiST": {
        "id": "wSTrtiST",
        "title": "Motion-robust intensity-modulated proton therapy for distal esophageal cancer",
        "abstract": "Purpose: To develop methods for evaluation and mitigation of dosimetric impact due to respiratory and diaphragmatic motion during free breathing in treatment of distal esophageal cancers using intensity-modulated proton therapy (IMPT). Methods: This was a retrospective study on 11 patients with distal esophageal cancer. For each patient, four-dimensional computed tomography (4D CT) data were acquired, and a nominal dose was calculated on the average phase of the 4D CT. The changes of water equivalent thickness (\u0394WET) to cover the treatment volume from the peak of inspiration to the valley of expiration were calculated for a full range of beam angle rotation. Two IMPT plans were calculated: one at beam angles corresponding to small \u0394WET and one at beam angles corresponding to large \u0394WET. Four patients were selected for the calculation of 4D-robustness-optimized IMPT plans due to large motion-induced dose errors generated in conventional IMPT. To quantitatively evaluate motion-induced dose deviation, the authors calculated the lowest dose received by 95% (D95) of the internal clinical target volume for the nominal dose, the D95 calculated on the maximum inhale and exhale phases of 4D CT      D      CT    0        and      D      CT    50        , the 4D composite dose, and the 4D dynamic dose for a single fraction. Results: The dose deviation increased with the average \u0394WET of the implemented beams, \u0394WETave. When \u0394WETave was less than 5 mm, the dose error was less than 1 cobalt gray equivalent based on DCT0 and DCT50. The dose deviation determined on the basis of DCT0 and DCT50 was proportionally larger than that determined on the basis of the 4D composite dose. The 4D-robustness-optimized IMPT plans notably reduced the overall dose deviation of multiple fractions and the dose deviation caused by the interplay effect in a single fraction. Conclusions: In IMPT for distal esophageal cancer, \u0394WET analysis can be used to select the beam angles that are least affected by respiratory and diaphragmatic motion. To further reduce dose deviation, the 4D-robustness optimization can be implemented for IMPT planning. Calculation of DCT0 and DCT50 is a conservative method to estimate the motion-induced dose errors.",
        "keywords": "",
        "authors": [
            {
                "name": "Jen Yu",
                "org": "University of Texas MD Anderson Cancer Center"
            },
            {
                "name": "Xiaodong Zhang",
                "org": "Proton Therapy Center and Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030"
            },
            {
                "name": "Li Liao",
                "org": "Department of Industrial Engineering, University of Houston, Houston, Texas 77004"
            },
            {
                "name": "Heng Li",
                "org": "Proton Therapy Center and Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030"
            },
            {
                "name": "Ronald X. Zhu",
                "org": "Proton Therapy Center and Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030"
            },
            {
                "name": "Peter C. Park",
                "org": "Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030"
            },
            {
                "name": "Narayan Sahoo",
                "org": "Proton Therapy Center and Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030"
            },
            {
                "name": "M Gillin",
                "org": "Proton Therapy Center and Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030"
            },
            {
                "name": "Yupeng Li",
                "org": ""
            },
            {
                "name": "Joe Y. Chang",
                "org": "Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030"
            },
            {
                "name": "Ritsuko Komaki",
                "org": "Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030"
            },
            {
                "name": "Steven H. Lin",
                "org": "Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030"
            }
        ],
        "venue": "Medical Physics",
        "year": 2016
    },
    "zm3p4ge2": {
        "id": "zm3p4ge2",
        "title": "SP-0501: Adaptive practice and techniques in proton therapy of the lung",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "P.C. Park",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Lei Dong",
                "org": ""
            },
            {
                "name": "Joe Y. Chang",
                "org": ""
            },
            {
                "name": "X Zhu",
                "org": ""
            }
        ],
        "venue": "Radiotherapy and Oncology",
        "year": 2016
    },
    "FtC1VBAs": {
        "id": "FtC1VBAs",
        "title": "Accounting for, Mitigating, and Choice of Margins for Moving Tumors",
        "abstract": "Tumor motion can lead to uncertainties in delivered dose to patients and undesirable outcomes. Motion management has become an integrated component of the standard of care for moving tumors in external beam radiotherapy with the development of novel imaging and treatment techniques in the past 2 decades. This article reviews the use of advanced and functional imaging to guide target delineation, considerations for margin selections, technique for accounting for and mitigation of tumor motion in treatment planning and delivery, and motion management in radiation therapy.",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": "Radiation Physics"
            },
            {
                "name": "Joe Y. Chang",
                "org": "Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX"
            }
        ],
        "venue": "Seminars in Radiation Oncology",
        "year": 2018
    },
    "PzI9CEkJ": {
        "id": "PzI9CEkJ",
        "title": "Proton therapy for early-stage non-small cell lung cancer (NSCLC)",
        "abstract": "In the setting of early-stage non-small cell lung cancer (NSCLC), defining the optimal clinical context for proton beam therapy (PBT) is challenging due to the increasing evidence demonstrating high rates of local control and good tolerance of stereotactic ablative body radiation (SABR). Given the relatively small percentage of lung and other critical structures treated with SABR, dosimetric studies comparing the two techniques have typically concluded that there are modest advantages to PBT, typically by reducing the low dose volumes, such as volume of lung receiving 5 Gy. This advantage may be more significant in treating larger tumors, multiple tumors, or central tumors. Most of the published studies are based on passive scattering PBT. Dosimetric benefits are likely to increase when pencil beam scanning/intensity-modulated proton therapy (IMPT) is employed, as has been observed in dosimetric reports in the locally advanced setting. More clinical data is needed regarding the safety and efficacy of stereotactic PBT in comparison to SABR. However, the only randomized trial that has been attempted closed early due to poor accrual, thus demonstrating the difficulty in designing trials in this context that incorporate a relevant and focused scientific question that can be extrapolated to clinical practice, yet also accrue sufficiently. The advent and increased use of advanced image-guided radiation therapy (IGRT) techniques in the context of proton therapy, as well as the widespread implementation of IMPT, will increase the potential benefit of PBT. The next 5\u201310 years will likely yield more appropriate, feasible studies that will help answer the question of patient selection for this advanced technology.",
        "keywords": "",
        "authors": [
            {
                "name": "Daniel R. Gomez",
                "org": "Cancer Center Support Grant (CCSG) Programs"
            },
            {
                "name": "Heng Li",
                "org": "University of Texas M. D. Anderson Cancer Center"
            },
            {
                "name": "Joe Y. Chang",
                "org": "Cancer Center Support Grant (CCSG) Programs"
            }
        ],
        "venue": "Translational lung cancer research",
        "year": 2018
    },
    "IZg9BT2e": {
        "id": "IZg9BT2e",
        "title": "Poster Viewing AbstractClinical Implementation of Intensity Modulated Proton Therapy in Thoracic Malignancies",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "J.Y. Chang",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Ronald X. Zhu",
                "org": ""
            },
            {
                "name": "Z. Liao",
                "org": ""
            },
            {
                "name": "Z. Lina",
                "org": ""
            },
            {
                "name": "A.L. Liu",
                "org": ""
            },
            {
                "name": "Z. Zhu",
                "org": ""
            },
            {
                "name": "Daniel R. Gomez",
                "org": ""
            },
            {
                "name": "R Wu",
                "org": ""
            },
            {
                "name": "M Gillin",
                "org": ""
            },
            {
                "name": "Xinna Zhang",
                "org": ""
            }
        ],
        "venue": "International Journal of Radiation Oncology Biology Physics",
        "year": 2014
    },
    "N5jWNg3C": {
        "id": "N5jWNg3C",
        "title": "A Method for Analyzing and Reporting Patterns of In-Field Recurrence after Definitive Concurrent Chemoradiation in Locally Advanced Non-Small Cell Lung Cancer",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Saumil J. Gandhi",
                "org": ""
            },
            {
                "name": "Chonnipa Nantavithya",
                "org": ""
            },
            {
                "name": "J.Y. Chang",
                "org": ""
            },
            {
                "name": "Steven H. Lin",
                "org": ""
            },
            {
                "name": "Z. Liao",
                "org": ""
            },
            {
                "name": "A.S. Mohamed",
                "org": ""
            },
            {
                "name": "C.D. Fuller",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Daniel R. Gomez",
                "org": ""
            }
        ],
        "venue": "International Journal of Radiation Oncology Biology Physics",
        "year": 2018
    },
    "iPQH6KiP": {
        "id": "iPQH6KiP",
        "title": "Predictive Model of Progression in Early Stage Non Small Cell Lung Cancer Treated with Stereotactic Ablative Radiation Therapy",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "H. Bahig",
                "org": ""
            },
            {
                "name": "Eric D. Brooks",
                "org": ""
            },
            {
                "name": "T. Zhang",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "James W. Welsh",
                "org": ""
            },
            {
                "name": "Steven H. Lin",
                "org": ""
            },
            {
                "name": "Daniel R. Gomez",
                "org": ""
            },
            {
                "name": "Saumil J. Gandhi",
                "org": ""
            },
            {
                "name": "John V. Heymach",
                "org": ""
            },
            {
                "name": "J.Y. Chang",
                "org": ""
            }
        ],
        "venue": "International Journal of Radiation Oncology Biology Physics",
        "year": 2018
    },
    "FOXabFfq": {
        "id": "FOXabFfq",
        "title": "Impact of Corticosteroid Administration on Outcomes Following Stereotactic Ablative Radiation Therapy for Non-Small Cell Lung Cancer",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Vivek Verma",
                "org": ""
            },
            {
                "name": "Eric D. Brooks",
                "org": ""
            },
            {
                "name": "Lei Feng",
                "org": ""
            },
            {
                "name": "T. Zhang",
                "org": ""
            },
            {
                "name": "James W. Welsh",
                "org": ""
            },
            {
                "name": "Steven H. Lin",
                "org": ""
            },
            {
                "name": "Daniel R. Gomez",
                "org": ""
            },
            {
                "name": "Saumil J. Gandhi",
                "org": ""
            },
            {
                "name": "John V. Heymach",
                "org": ""
            },
            {
                "name": "J.Y. Chang",
                "org": ""
            }
        ],
        "venue": "International Journal of Radiation Oncology Biology Physics",
        "year": 2018
    },
    "sguyFXou": {
        "id": "sguyFXou",
        "title": "Clinical Outcome of Intensity Modulated Proton Therapy for Non-Small Cell Lung Cancer",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Jennifer C. Ho",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Pamela K. Allen",
                "org": ""
            },
            {
                "name": "Xinna Zhang",
                "org": ""
            },
            {
                "name": "Z. Liao",
                "org": ""
            },
            {
                "name": "X Zhu",
                "org": ""
            },
            {
                "name": "Daniel R. Gomez",
                "org": ""
            },
            {
                "name": "Steven H. Lin",
                "org": ""
            },
            {
                "name": "M Gillin",
                "org": ""
            },
            {
                "name": "R. Komaki",
                "org": ""
            },
            {
                "name": "Stephen M. Hahn",
                "org": ""
            },
            {
                "name": "J.Y. Chang",
                "org": ""
            }
        ],
        "venue": "International Journal of Radiation Oncology Biology Physics",
        "year": 2015
    },
    "t5czW5jH": {
        "id": "t5czW5jH",
        "title": "Renoprotective effect of erythropoietin via modulation of the STAT6/MAPK/NF-\u03baB pathway in ischemia/reperfusion injury after renal transplantation.",
        "abstract": "Ischemia/reperfusion injury\u00a0(IRI) commonly occurs in renal transplantation. Erythropoietin\u00a0(EPO) exerts a protective effect in IRI. To investigate the underlying molecular mechanism, rat models of renal IRI were established and treated with EPO and/or lentivirus\u2011mediated EPO-siRNA, the signal transducer and activator of transcription\u00a06\u00a0(STAT6) inhibitor\u00a0AS1517499, the JNK inhibitor SP600125, the p38\u00a0mitogen-activated protein kinase\u00a0(MAPK) inhibitor\u00a0SB203580, and the nuclear factor\u00a0(NF)-\u03baB inhibitor lactacystin. Histological examination revealed that EPO protected the kidney from IRI, through decreasing the extent of tissue congestion and inflammatory cell infiltration; however, EPO\u00a0siRNA did not exert the same protective effect. In addition, the EPO level was inversely associated with renal IRI. EPO downregulated the expression of interferon-\u03b3, interleukin\u00a0(IL)-4, creatinine and caspase-3, and upregulated the expression of IL-10, thymic stromal lymphopoietin, STAT6, p-JNK and p-p38, while the opposite effects were observed with the administration of EPO-siRNA and the specific respective inhibitors. Further results revealed that MAPK (p-JNK and\u00a0p-p38) acted upstream of NF-\u03baB, and that NF-\u03baB signaling regulated the expression of caspase-1 and\u00a0-3, which may be responsible for the cytotoxicity associated with IRI. Taken together, the results of the present study demonstrated that EPO exerted a protective effect in renal IRI via the STAT6/MAPK/NF-\u03baB pathway. This protective effect of EPO may improve reperfusion tolerance in ischemic kidneys and benefit transplant recipients.",
        "keywords": "",
        "authors": [
            {
                "name": "Jinhua Zhang",
                "org": "Department of Kidney Transplantation, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510630, P.R. China."
            },
            {
                "name": "Daqiang Zhao",
                "org": "Department of Kidney Transplantation, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510630, P.R. China."
            },
            {
                "name": "Ning Na",
                "org": "Department of Kidney Transplantation, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510630, P.R. China."
            },
            {
                "name": "Heng Li",
                "org": "Department of Kidney Transplantation, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510630, P.R. China."
            },
            {
                "name": "Bin Miao",
                "org": "Department of Kidney Transplantation, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510630, P.R. China."
            },
            {
                "name": "Liangqing Hong",
                "org": "Department of Kidney Transplantation, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510630, P.R. China."
            },
            {
                "name": "Zhengyu Huang",
                "org": "Department of Kidney Transplantation, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510630, P.R. China."
            }
        ],
        "venue": "International journal of molecular medicine",
        "year": 2018
    },
    "Gfl2GwXG": {
        "id": "Gfl2GwXG",
        "title": "Allogeneic mesenchymal stem cells as induction therapy are safe and feasible in renal allografts: pilot results of a multicenter randomized controlled trial.",
        "abstract": "Umbilical-cord-derived MSCs can be used as clinically feasible and safe induction therapy. Adequate timing and frequency of UC-MSCs administration may have a significant effect on graft and recipient outcomes. Trial registration NCT02490020 . Registered on June 29 2015.",
        "keywords": [
            "Acute rejection",
            "DGF",
            "Delayed graft function",
            "MSC",
            "Mesenchymal stem cell",
            "Renal transplantation"
        ],
        "authors": [
            {
                "name": "Qipeng Sun",
                "org": "Department of Renal Transplantation, The Third Affiliated Hospital, Sun Yat-sen University, Kaichuang Road 2693, Huangpu District, Guangzhou, 510530, People's Republic of China."
            },
            {
                "name": "Zhengyu Huang",
                "org": "Department of Renal Transplantation, The Third Affiliated Hospital, Sun Yat-sen University, Kaichuang Road 2693, Huangpu District, Guangzhou, 510530, People's Republic of China."
            },
            {
                "name": "Fei Han",
                "org": "Department of Renal Transplantation, The Third Affiliated Hospital, Sun Yat-sen University, Kaichuang Road 2693, Huangpu District, Guangzhou, 510530, People's Republic of China."
            },
            {
                "name": "Ming Zhao",
                "org": "Department of Renal Transplantation, Zhujiang Hospital, Southern Medical University, Gongye Road 253, Guangzhou, 510280, People's Republic of China."
            },
            {
                "name": "Ronghua Cao",
                "org": "Department of Renal Transplantation, The Second Affiliated Hospital, Guangzhou Traditional Chinese Medicine University, Inner Ring Road 55, University City, Guangzhou, 510280, People's Republic of China."
            },
            {
                "name": "Daqiang Zhao",
                "org": "Department of Renal Transplantation, The Third Affiliated Hospital, Sun Yat-sen University, Kaichuang Road 2693, Huangpu District, Guangzhou, 510530, People's Republic of China."
            },
            {
                "name": "Liangqing Hong",
                "org": "Department of Renal Transplantation, The Third Affiliated Hospital, Sun Yat-sen University, Kaichuang Road 2693, Huangpu District, Guangzhou, 510530, People's Republic of China."
            },
            {
                "name": "Ning Na",
                "org": "Department of Renal Transplantation, The Third Affiliated Hospital, Sun Yat-sen University, Kaichuang Road 2693, Huangpu District, Guangzhou, 510530, People's Republic of China."
            },
            {
                "name": "Heng Li",
                "org": "Department of Renal Transplantation, The Third Affiliated Hospital, Sun Yat-sen University, Kaichuang Road 2693, Huangpu District, Guangzhou, 510530, People's Republic of China."
            },
            {
                "name": "Bin Miao",
                "org": "Department of Renal Transplantation, The Third Affiliated Hospital, Sun Yat-sen University, Kaichuang Road 2693, Huangpu District, Guangzhou, 510530, People's Republic of China."
            },
            {
                "name": "Jianmin Hu",
                "org": "Department of Renal Transplantation, Zhujiang Hospital, Southern Medical University, Gongye Road 253, Guangzhou, 510280, People's Republic of China."
            },
            {
                "name": "Fanhang Meng",
                "org": "Department of Renal Transplantation, The Second Affiliated Hospital, Guangzhou Traditional Chinese Medicine University, Inner Ring Road 55, University City, Guangzhou, 510280, People's Republic of China."
            },
            {
                "name": "Yanwen Peng",
                "org": "Cell-gene Therapy Translational Medicine Research Center, The Third Affiliated Hospital, Sun Yat-sen University, Tianhe Road 600, Guangzhou, 510630, People's Republic of China."
            },
            {
                "name": "Qiquan Sun",
                "org": "Department of Renal Transplantation, The Third Affiliated Hospital, Sun Yat-sen University, Kaichuang Road 2693, Huangpu District, Guangzhou, 510530, People's Republic of China. sunqiq@mail.sysu.edu.cn."
            }
        ],
        "venue": "Journal of translational medicine",
        "year": 2018
    },
    "a8Ev6bel": {
        "id": "a8Ev6bel",
        "title": "High expression of HMGA2 predicts poor survival in patients with clear cell renal cell carcinoma.",
        "abstract": "High-mobility group AT-hook 2 (HMGA2) is involved in a wide spectrum of biological processes and is upregulated in several tumors, but its role in renal carcinoma remains unclear. The aim of this study was to examine the expression of HMGA2 and its relationship to the overall survival (OS) of patients with non-metastatic clear cell renal cell carcinoma (ccRCC) following surgery. The expression of HMGA2 was evaluated retrospectively by immunohistochemistry (IHC) in 162 patients with ccRCC who underwent nephrectomy in 2003 and 2004. An IHC analysis revealed that HMGA2 was expressed in the nuclei of tumor cells in 146 (90.1%) patients with ccRCC. The level of HMGA2 was positively correlated with tumor size, lymph node metastasis, and Fuhrman Grade. A Kaplan-Meier analysis with log-rank test found that patients with high HMGA2 expression had a poor outcome and that patients with low HMGA2 expression had better survival. Cox regression analysis showed that HMGA2 expression could serve as an independent prognostic factor for ccRCC patients. The efficacy of the following prognostic models was improved when HMGA2 expression was added: tumor node metastasis stage, UCLA Integrated Scoring System, Mayo Clinic stage, size, grade, and necrosis score. In summary, this study showed that HMGA2 expression is an independent prognostic factor for OS in patients with ccRCC. HMGA2 was found to be a valuable biomarker for ccRCC progression.",
        "keywords": [
            "high-mobility group protein A",
            "prognosis",
            "renal carcinoma"
        ],
        "authors": [
            {
                "name": "Ning Na",
                "org": "Department of Kidney Transplantation, The Third Affiliated Hospital of Sun Yat-sen University."
            },
            {
                "name": "Tujie Si",
                "org": "Department of Organ Transplant, The First Affiliated Hospital of Sun Yat-sen University."
            },
            {
                "name": "Zhengyu Huang",
                "org": "Department of Kidney Transplantation, The Third Affiliated Hospital of Sun Yat-sen University."
            },
            {
                "name": "Bin Miao",
                "org": "Department of Kidney Transplantation, The Third Affiliated Hospital of Sun Yat-sen University."
            },
            {
                "name": "Liangqing Hong",
                "org": "Department of Kidney Transplantation, The Third Affiliated Hospital of Sun Yat-sen University."
            },
            {
                "name": "Heng Li",
                "org": "Department of Kidney Transplantation, The Third Affiliated Hospital of Sun Yat-sen University."
            },
            {
                "name": "Jiang Qiu",
                "org": "Department of Organ Transplant, The First Affiliated Hospital of Sun Yat-sen University."
            },
            {
                "name": "Jianguang Qiu",
                "org": "Department of Urology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China."
            }
        ],
        "venue": "OncoTargets and therapy",
        "year": 2016
    },
    "uGzAVKVG": {
        "id": "uGzAVKVG",
        "title": "High expression of Aldolase A predicts poor survival in patients with clear-cell renal cell carcinoma.",
        "abstract": "Our results suggest that ALDOA expression is an independent prognostic factor for OS in patients with ccRCC.",
        "keywords": [
            "Aldolase A",
            "glycolysis",
            "prognosis",
            "renal carcinoma"
        ],
        "authors": [
            {
                "name": "Ning Na",
                "org": "Department of Kidney Transplantation."
            },
            {
                "name": "Heng Li",
                "org": "Department of Kidney Transplantation."
            },
            {
                "name": "Chengfang Xu",
                "org": "Department of Obstetrics and Genecology, The Third Affiliated Hospital of Sun Yat-sen University."
            },
            {
                "name": "Bin Miao",
                "org": "Department of Kidney Transplantation."
            },
            {
                "name": "Liangqing Hong",
                "org": "Department of Kidney Transplantation."
            },
            {
                "name": "Zhengyu Huang",
                "org": "Department of Kidney Transplantation."
            },
            {
                "name": "Qiu Jiang",
                "org": "Department of Organ Transplantation, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, People's Republic of China."
            }
        ],
        "venue": "Therapeutics and clinical risk management",
        "year": 2017
    },
    "coPEagIB": {
        "id": "coPEagIB",
        "title": "Meta-analysis of the efficacy of the pretreatment neutrophil-to-lymphocyte ratio as a predictor of prognosis in renal carcinoma patients receiving tyrosine kinase inhibitors",
        "abstract": "//      Ning Na 1,  * , Jia Yao 2,  * , Cailian Cheng 3,  * , Zhengyu Huang 1 , Liangqing Hong 1 , Heng Li 1 , Jiang Qiu 4     1 Department of Kidney Transplantation, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong Province 510630, China    2 Department of Hepatic Surgery, Liver Transplantation Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong Province 510630, China    3 Department of Nephrology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong Province 510630, China    4 Department of Organ Transplant, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong Province 510080, China    * These authors have contributed equally to this work   Correspondence to:   Jiang Qiu, email:  qjiang_sysu@126.com     Keywords:  renal cancer, neutrophil-to-lymphocyte ratio, prognosis marker, target therapy, meta-analysis    Received:  November 29, 2015\u2003\u2003\u2003\u2003 Accepted:  April 26, 2016\u2003\u2003\u2003\u2003 Published:  June 06, 2016     ABSTRACT   The data on the impact of the neutrophil-to-lymphocyte ratio (NLR) in metastatic renal cell carcinoma (mRCC) patients receiving tyrosine kinase inhibitors (TKIs) are inconsistent. We therefore performed a meta-analysis to assess the prognostic value of pretreatment NLR in patients treated with TKIs for mRCC. We searched the Embase, Medline, PubMed, Cochrane and ISI Web of Knowledge to identify clinical studies that had evaluated the association between the pretreatment NLR and prognosis in mRCC patients. Prognostic outcomes included overall survival (OS) and progression-free survival (PFS). Nine studies encompassing a total of 1091 participants were included. We found that a high NLR was an effective prognostic marker of both OS (pooled HR: 1.93, 95% CI: 1.35-2.77; P = 0.0003) and PFS (pooled HR: 2.12, 95% CI: 1.42-3.17; P = 0.0002). Subgroup analysis revealed that studies reporting a NLR \u2265 3 showed a more significant effect of NLR on both OS (pooled HR: 2.50, 95% CI: 1.99-3.14; P = 0.0003) and PFS (pooled HR: 2.17, 95% CI: 1.26-3.75). This meta-analysis suggests that high pretreatment NLR is associated with a poor prognosis in mRCC patients receiving TKI treatment.",
        "keywords": "",
        "authors": [
            {
                "name": "Ning Na",
                "org": ""
            },
            {
                "name": "Jia Yao",
                "org": ""
            },
            {
                "name": "Cailian Cheng",
                "org": ""
            },
            {
                "name": "Zhengyu Huang",
                "org": ""
            },
            {
                "name": "Liangqing Hong",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Jiang Qiu",
                "org": ""
            }
        ],
        "venue": "Oncotarget",
        "year": 2016
    },
    "qFyL0b7h": {
        "id": "qFyL0b7h",
        "title": "Euryachins A and B, a new type of diterpenoids from Eurya chinensis with potent NO production inhibitory activity",
        "abstract": "Euryachins A (1) and B (2), a new type of tetracyclic diterpenoid named a euryamane type, were isolated from the branches of Eurya chinensis. Their structures were elucidated through extensive spectroscopic analysis with the absolute configuration of 1 determined by single crystal X-ray diffraction analysis. A biogenetic pathway was proposed to account for the formation of this new type of diterpenoid. Both 1 and 2 exhibited anti-inflammatory activities with potencies comparable to the positive control L-NMMA, as evaluated against NO production in LPS-stimulated RAW264.7 cells.",
        "keywords": "",
        "authors": [
            {
                "name": "Jia-Ling Song",
                "org": "Program for Natural Product Chemical Biology, Key Laboratory of Plant Resources, Conservation and Sustainable Utilization, South China Botanical Garden, Chinese Academy of Sciences,Guangzhou,P. R. China"
            },
            {
                "name": "Yao Yuan",
                "org": "Program for Natural Product Chemical Biology, Key Laboratory of Plant Resources, Conservation and Sustainable Utilization, South China Botanical Garden, Chinese Academy of Sciences,Guangzhou,P. R. China"
            },
            {
                "name": "Hai-Bo Tan",
                "org": "Program for Natural Product Chemical Biology, Key Laboratory of Plant Resources, Conservation and Sustainable Utilization, South China Botanical Garden, Chinese Academy of Sciences,Guangzhou,P. R. China"
            },
            {
                "name": "Jie-Wei Wu",
                "org": ""
            },
            {
                "name": "Riming Huang",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": "Department of Kidney Transplantation, The Third Affiliated Hospital of Sun Yat-sen University,Guangzhou,P. R. China"
            },
            {
                "name": "Zhifang Xu",
                "org": "Program for Natural Product Chemical Biology, Key Laboratory of Plant Resources, Conservation and Sustainable Utilization, South China Botanical Garden, Chinese Academy of Sciences,Guangzhou,P. R. China"
            },
            {
                "name": "Ning Na",
                "org": "Department of Kidney Transplantation, The Third Affiliated Hospital of Sun Yat-sen University,Guangzhou,P. R. China"
            },
            {
                "name": "Sheng-Xiang Qiu",
                "org": "Program for Natural Product Chemical Biology, Key Laboratory of Plant Resources, Conservation and Sustainable Utilization, South China Botanical Garden, Chinese Academy of Sciences,Guangzhou,P. R. China"
            }
        ],
        "venue": "RSC Advances",
        "year": 2016
    },
    "ts7XCtaj": {
        "id": "ts7XCtaj",
        "title": "Practical guidelines for handling head and neck computed tomography artifacts for quantitative image analysis.",
        "abstract": "Radiomics studies have demonstrated the potential use of quantitative image features to improve prognostic stratification of patients with head and neck cancer. Imaging protocol parameters that can affect radiomics feature values have been investigated, but the effects of artifacts caused by intrinsic patient factors have not. Two such artifacts that are common in patients with head and neck cancer are streak artifacts caused by dental fillings and beam-hardening artifacts caused by bone. The purpose of this study was to test the impact of these artifacts and if needed, methods for compensating for these artifacts in head and neck radiomics studies. The robustness of feature values was tested by removing slices of the gross tumor volume (GTV) on computed tomography images from 30 patients with head and neck cancer; these images did not have streak artifacts or had artifacts far from the GTV. The range of each feature value over a percentage of the GTV was compared to the inter-patient variability at full volume. To determine the effects of beam-hardening artifacts, we scanned a phantom with 5 cartridges of different materials encased in polystyrene buildup. A cylindrical hole through the cartridges contained either a rod of polylactic acid to simulate water or a rod of polyvinyl chloride to simulate bone. A region of interest was drawn in each cartridge flush with the rod. Most features were robust with up to 50% of the original GTV removed. Most feature values did not significantly differ when measured with the polylactic acid rod or the polyvinyl chloride rod. Of those that did, the size of the difference did not exceed the inter-patient standard deviation in most cases. We conclude that simply removing slices affected by streak artifacts can enable these scans to be included in radiomics studies and that contours of structures can abut bone without being affected by beam hardening if needed.",
        "keywords": [
            "Artifacts",
            "Head and neck",
            "Quantitative imaging",
            "Radiomics",
            "Texture"
        ],
        "authors": [
            {
                "name": "Rachel B. Ger",
                "org": "Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 1420, Houston, Texas 77030, United States; The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, 6767 Bertner Ave., Houston, Texas 77030, United States. Electronic address: rbger@mdanderson.org."
            },
            {
                "name": "Daniel F. Craft",
                "org": "Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 1420, Houston, Texas 77030, United States; The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, 6767 Bertner Ave., Houston, Texas 77030, United States."
            },
            {
                "name": "Dennis S. Mackin",
                "org": "Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 1420, Houston, Texas 77030, United States; The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, 6767 Bertner Ave., Houston, Texas 77030, United States."
            },
            {
                "name": "Shouhao Zhou",
                "org": "The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, 6767 Bertner Ave., Houston, Texas 77030, United States; Department of Biostatistics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 1411, Houston, Texas 77030, United States."
            },
            {
                "name": "Rick R. Layman",
                "org": "The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, 6767 Bertner Ave., Houston, Texas 77030, United States; Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 1472, Houston, Texas 77030, United States."
            },
            {
                "name": "A. Kyle Jones",
                "org": "The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, 6767 Bertner Ave., Houston, Texas 77030, United States; Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 1472, Houston, Texas 77030, United States."
            },
            {
                "name": "Hesham Elhalawani",
                "org": "Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 0097, Houston, Texas 77030, United States."
            },
            {
                "name": "Clifton D. Fuller",
                "org": "The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, 6767 Bertner Ave., Houston, Texas 77030, United States; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 0097, Houston, Texas 77030, United States."
            },
            {
                "name": "Rebecca M. Howell",
                "org": "Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 1420, Houston, Texas 77030, United States; The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, 6767 Bertner Ave., Houston, Texas 77030, United States."
            },
            {
                "name": "Heng Li",
                "org": "Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 1420, Houston, Texas 77030, United States; The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, 6767 Bertner Ave., Houston, Texas 77030, United States."
            },
            {
                "name": "R. Jason Stafford",
                "org": "The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, 6767 Bertner Ave., Houston, Texas 77030, United States; Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 1472, Houston, Texas 77030, United States."
            },
            {
                "name": "Laurence E. Court",
                "org": "Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 1420, Houston, Texas 77030, United States; The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, 6767 Bertner Ave., Houston, Texas 77030, United States; Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 1472, Houston, Texas 77030, United States."
            }
        ],
        "venue": "Comp. Med. Imag. and Graph.",
        "year": 2018
    },
    "8OiM0qmf": {
        "id": "8OiM0qmf",
        "title": "Synthetic Head and Neck and Phantom Images for Determining Deformable Image Registration Accuracy in Magnetic Resonance Imaging.",
        "abstract": "The proposed database provides two sets of images (one acquired and one computer generated) for use in evaluating deformable image registration accuracy. T1- and T2-weighted images are available for each technique as the different image contrast in the two types of images may impact the registration accuracy. This article is protected by copyright. All rights reserved.",
        "keywords": "",
        "authors": [
            {
                "name": "Rachel B Ger",
                "org": "The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX, 77030, USA."
            },
            {
                "name": "Jinzhong Yang",
                "org": "The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX, 77030, USA."
            },
            {
                "name": "Yao Ding",
                "org": "Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA."
            },
            {
                "name": "Megan C Jacobsen",
                "org": "Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA."
            },
            {
                "name": "Carlos E Cardenas",
                "org": "The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX, 77030, USA."
            },
            {
                "name": "Clifton D Fuller",
                "org": "Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA."
            },
            {
                "name": "Rebecca M Howell",
                "org": "The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX, 77030, USA."
            },
            {
                "name": "Heng Li",
                "org": "The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX, 77030, USA."
            },
            {
                "name": "R Jason Stafford",
                "org": "Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA."
            },
            {
                "name": "Shouhao Zhou",
                "org": "Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA."
            },
            {
                "name": "Laurence E Court",
                "org": "Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA."
            }
        ],
        "venue": "Medical physics",
        "year": 2018
    },
    "nyNthLqY": {
        "id": "nyNthLqY",
        "title": "Erratum: Dynamic contrast-enhanced magnetic resonance imaging for head and neck cancers",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Joint Head",
                "org": ""
            },
            {
                "name": "Hesham Elhalawani",
                "org": ""
            },
            {
                "name": "Rachel B. Ger",
                "org": ""
            },
            {
                "name": "Abdallah S.R. Mohamed",
                "org": ""
            },
            {
                "name": "Musaddiq J. Awan",
                "org": ""
            },
            {
                "name": "Yao Ding",
                "org": ""
            },
            {
                "name": "Kimberly Li",
                "org": ""
            },
            {
                "name": "Xenia Fave",
                "org": ""
            },
            {
                "name": "Andrew Beers",
                "org": ""
            },
            {
                "name": "Brandon Driscoll",
                "org": ""
            },
            {
                "name": "David A. Hormuth",
                "org": ""
            },
            {
                "name": "Petra J. van Houdt",
                "org": ""
            },
            {
                "name": "Renjie He",
                "org": ""
            },
            {
                "name": "Shouhao Zhou",
                "org": ""
            },
            {
                "name": "Kelsey B. Mathieu",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "C. Coolens",
                "org": ""
            },
            {
                "name": "Caroline Chung",
                "org": ""
            },
            {
                "name": "James A. Bankson",
                "org": ""
            },
            {
                "name": "Wei Huang",
                "org": ""
            },
            {
                "name": "Jihong Wang",
                "org": ""
            },
            {
                "name": "Vlad C. Sandulache",
                "org": ""
            },
            {
                "name": "Stephen Y. Lai",
                "org": ""
            },
            {
                "name": "Rebecca M. Howell",
                "org": ""
            },
            {
                "name": "R. Jason Stafford",
                "org": ""
            },
            {
                "name": "Thomas E. Yankeelov",
                "org": ""
            },
            {
                "name": "Uulke A. van der Heide",
                "org": ""
            },
            {
                "name": "Steven J. Frank",
                "org": ""
            },
            {
                "name": "Daniel P. Barboriak",
                "org": ""
            },
            {
                "name": "John D. Hazle",
                "org": ""
            },
            {
                "name": "L Court",
                "org": ""
            },
            {
                "name": "Jayashree Kalpathy-Cramer",
                "org": ""
            },
            {
                "name": "Clifton D. Fuller",
                "org": ""
            }
        ],
        "venue": "Scientific Data",
        "year": 2018
    },
    "QceyrBZX": {
        "id": "QceyrBZX",
        "title": "Data descriptor: Dynamic contrastenhanced magnetic resonance imaging for head and neck cancers",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Hesham Elhalawani",
                "org": "University of Texas M. D. Anderson Cancer Center"
            },
            {
                "name": "Rachel B. Ger",
                "org": "University of Texas M. D. Anderson Cancer Center"
            },
            {
                "name": "Rachel B. Ger",
                "org": "University of Texas M. D. Anderson Cancer Center"
            },
            {
                "name": "Abdallah S.R. Mohamed",
                "org": "University of Texas M. D. Anderson Cancer Center"
            },
            {
                "name": "Abdallah S.R. Mohamed",
                "org": "University of Texas M. D. Anderson Cancer Center"
            },
            {
                "name": "Musaddiq J. Awan",
                "org": "Case Western Reserve University"
            },
            {
                "name": "Yao Ding",
                "org": "University of Texas M. D. Anderson Cancer Center"
            },
            {
                "name": "Kimberly Li",
                "org": "Oregon Health and Science University"
            },
            {
                "name": "Xenia Fave",
                "org": "University of Texas M. D. Anderson Cancer Center"
            },
            {
                "name": "Xenia Fave",
                "org": "University of Texas M. D. Anderson Cancer Center"
            },
            {
                "name": "Andrew Beers",
                "org": "Massachusetts Institute of Technology"
            },
            {
                "name": "Brandon Driscoll",
                "org": "University of Toronto"
            },
            {
                "name": "David A. Hormuth",
                "org": "University of Texas at Austin"
            },
            {
                "name": "Petra J. van Houdt",
                "org": "Netherlands Cancer Institute"
            },
            {
                "name": "Renjie He",
                "org": "United Imaging Healthcare America"
            },
            {
                "name": "Shouhao Zhou",
                "org": "University of Texas M. D. Anderson Cancer Center"
            },
            {
                "name": "Kelsey B. Mathieu",
                "org": "University of Texas M. D. Anderson Cancer Center"
            },
            {
                "name": "Heng Li",
                "org": "University of Texas M. D. Anderson Cancer Center"
            },
            {
                "name": "Heng Li",
                "org": "University of Texas M. D. Anderson Cancer Center"
            },
            {
                "name": "C. Coolens",
                "org": "University of Toronto"
            },
            {
                "name": "Caroline Chung",
                "org": "University of Texas M. D. Anderson Cancer Center"
            },
            {
                "name": "Caroline Chung",
                "org": "University of Texas M. D. Anderson Cancer Center"
            },
            {
                "name": "James A. Bankson",
                "org": "University of Texas Health Science Center at Houston"
            },
            {
                "name": "James A. Bankson",
                "org": "University of Texas Health Science Center at Houston"
            },
            {
                "name": "Wei Huang",
                "org": "Oregon Health and Science University"
            },
            {
                "name": "Jihong Wang",
                "org": "University of Texas M. D. Anderson Cancer Center"
            },
            {
                "name": "Jihong Wang",
                "org": "University of Texas M. D. Anderson Cancer Center"
            },
            {
                "name": "Vlad C. Sandulache",
                "org": "Baylor College of Medicine"
            },
            {
                "name": "Stephen Y. Lai",
                "org": "University of Texas M. D. Anderson Cancer Center"
            },
            {
                "name": "Rebecca M. Howell",
                "org": "University of Texas M. D. Anderson Cancer Center"
            },
            {
                "name": "Rebecca M. Howell",
                "org": "University of Texas M. D. Anderson Cancer Center"
            },
            {
                "name": "R. Jason Stafford",
                "org": ""
            },
            {
                "name": "R. Jason Stafford",
                "org": ""
            },
            {
                "name": "Thomas E. Yankeelov",
                "org": "University of Texas at Austin"
            },
            {
                "name": "Uulke A. van der Heide",
                "org": ""
            },
            {
                "name": "Steven J. Frank",
                "org": "University of Texas M. D. Anderson Cancer Center"
            },
            {
                "name": "Daniel P. Barboriak",
                "org": "Duke University"
            },
            {
                "name": "John D. Hazle",
                "org": "University of Texas Health Science Center at Houston"
            },
            {
                "name": "John D. Hazle",
                "org": "University of Texas Health Science Center at Houston"
            },
            {
                "name": "L Court",
                "org": "University of Texas M. D. Anderson Cancer Center"
            },
            {
                "name": "L Court",
                "org": "University of Texas M. D. Anderson Cancer Center"
            },
            {
                "name": "Jayashree Kalpathy-Cramer",
                "org": "Massachusetts Institute of Technology"
            },
            {
                "name": "Clifton D. Fuller",
                "org": "Radiation Oncology"
            }
        ],
        "venue": "Scientific Data",
        "year": 2018
    },
    "2MIIwgBH": {
        "id": "2MIIwgBH",
        "title": "Publisher Correction: A Multi-Institutional Comparison of Dynamic Contrast-Enhanced Magnetic Resonance Imaging Parameter Calculations (Scientific Reports (2017) DOI: 10.1038/s41598-017-11554-w)",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Rachel B. Ger",
                "org": "University of Texas MD Anderson Cancer Center"
            },
            {
                "name": "Rachel B. Ger",
                "org": "University of Texas MD Anderson Cancer Center"
            },
            {
                "name": "Abdallah S.R. Mohamed",
                "org": "University of Texas MD Anderson Cancer Center"
            },
            {
                "name": "Abdallah S.R. Mohamed",
                "org": "University of Texas MD Anderson Cancer Center"
            },
            {
                "name": "Musaddiq J. Awan",
                "org": "Case Western Reserve University"
            },
            {
                "name": "Yao Ding",
                "org": "University of Texas MD Anderson Cancer Center"
            },
            {
                "name": "Kimberly Li",
                "org": "Oregon Health and Science University"
            },
            {
                "name": "Xenia Fave",
                "org": "University of Texas MD Anderson Cancer Center"
            },
            {
                "name": "Xenia Fave",
                "org": "University of Texas MD Anderson Cancer Center"
            },
            {
                "name": "Andrew Beers",
                "org": "Massachusetts Institute of Technology"
            },
            {
                "name": "Brandon Driscoll",
                "org": "University of Toronto"
            },
            {
                "name": "Hesham Elhalawani",
                "org": "University of Texas MD Anderson Cancer Center"
            },
            {
                "name": "David A. Hormuth",
                "org": "University of Texas at Austin"
            },
            {
                "name": "Petra J. van Houdt",
                "org": "Netherlands Cancer Institute"
            },
            {
                "name": "Renjie He",
                "org": "United Imaging Healthcare America"
            },
            {
                "name": "Shouhao Zhou",
                "org": "University of Texas MD Anderson Cancer Center"
            },
            {
                "name": "Kelsey B. Mathieu",
                "org": "University of Texas MD Anderson Cancer Center"
            },
            {
                "name": "Heng Li",
                "org": "University of Texas MD Anderson Cancer Center"
            },
            {
                "name": "C. Coolens",
                "org": "University of Toronto"
            },
            {
                "name": "C. Coolens",
                "org": "University of Toronto"
            },
            {
                "name": "Caroline Chung",
                "org": "University of Toronto"
            },
            {
                "name": "James A. Bankson",
                "org": "University of Texas Health Science Center at Houston"
            },
            {
                "name": "Wei Huang",
                "org": "Oregon Health and Science University"
            },
            {
                "name": "Jihong Wang",
                "org": "University of Texas MD Anderson Cancer Center"
            },
            {
                "name": "Vlad C. Sandulache",
                "org": "Baylor College of Medicine"
            },
            {
                "name": "Stephen Y. Lai",
                "org": "University of Texas MD Anderson Cancer Center"
            },
            {
                "name": "Rebecca M. Howell",
                "org": "University of Texas MD Anderson Cancer Center"
            },
            {
                "name": "R. Jason Stafford",
                "org": ""
            },
            {
                "name": "Thomas E. Yankeelov",
                "org": "University of Texas at Austin"
            },
            {
                "name": "Uulke A. van der Heide",
                "org": ""
            },
            {
                "name": "Steven J. Frank",
                "org": "Cancer Center Support Grant (CCSG) Programs"
            },
            {
                "name": "Daniel P. Barboriak",
                "org": "Duke University Medical Center"
            },
            {
                "name": "John D. Hazle",
                "org": ""
            },
            {
                "name": "L Court",
                "org": "University of Texas MD Anderson Cancer Center"
            },
            {
                "name": "Jayashree Kalpathy-Cramer",
                "org": "Massachusetts Institute of Technology"
            },
            {
                "name": "Clifton D. Fuller",
                "org": "University of Texas Health Science Center at Houston"
            }
        ],
        "venue": "Scientific Reports",
        "year": 2018
    },
    "4pd4JdX0": {
        "id": "4pd4JdX0",
        "title": "Androgen-receptor splice variant-7-positive prostate cancer: a novel molecular subtype with markedly worse androgen-deprivation therapy outcomes in newly diagnosed patients",
        "abstract": "Androgen-deprivation therapy has been the standard treatment for metastatic and locally advanced prostate cancer, but the majority of patients will progress to castration-resistant prostate cancer within 2\u20133 years. Unlike the case in breast cancer, no clinically validated biomarker has been used to predict the outcomes of androgen-deprivation therapy. To evaluate androgen-receptor splice variant-7 (AR-V7) detection in newly diagnosed advanced prostate cancer and describe the distinctive prognosis of this novel molecular subtype, this study retrospectively enrolled 168 newly diagnosed prostate cancer patients from 2003 to 2015 who received androgen-deprivation therapy. AR-V7 immunohistochemical staining was performed with a monoclonal antibody, and AR-V7 expression was determined using Immune-Reactive Score data. The association between nuclear AR-V7 expression and prognosis was determined. Multiple cause-specific Cox regression and stratified cumulative incidences were used to analyze the prognosis risk. Among the 168 patients, 32 (19%) were AR-V7-positive. Compared with the AR-V7-negative patients, the AR-V7-positive patients had significantly lower prostate-specific antigen response rates (P<0.001) to androgen-deprivation therapy and a much shorter time to castration-resistant prostate cancer (P<0.0001). In Kaplan\u2013Meier analysis, the AR-V7-positive group showed markedly lower castration-resistant prostate cancer progression-free survival (P<0.0001) and much lower cancer-specific (P<0.0001) and overall survival (P<0.0001) both in all enrolled patients and in patients with metastases. AR-V7 positivity was a significant predictor of castration-resistant prostate cancer progression in multiple Cox regression (hazard ratio: 4.826; 95% CI: 2.960\u20137.869; P<0.001). AR-V7 immunohistochemical detection in newly diagnosed prostate cancer patients who are planning to receive androgen-deprivation therapy, especially those with metastases, is necessary and valuable for prognostic assessment. AR-V7-positive prostate cancer should be considered a novel prostate cancer subtype that should be distinguished upon initial biopsy. The main limitation of this study is its observational nature.",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Zhize Wang",
                "org": ""
            },
            {
                "name": "Wei Xiao",
                "org": ""
            },
            {
                "name": "Libin Yan",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."
            },
            {
                "name": "Wei Guan",
                "org": ""
            },
            {
                "name": "Zhiquan Hu",
                "org": ""
            },
            {
                "name": "Lily Wu",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."
            },
            {
                "name": "Qihong Huang",
                "org": ""
            },
            {
                "name": "Ji Wang",
                "org": ""
            },
            {
                "name": "Hua Xu",
                "org": "The Wistar Institute, Philadelphia, PA, USA."
            },
            {
                "name": "Xu Zhang",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."
            },
            {
                "name": "Zhangqun Ye",
                "org": "Department of Urology/State Key Laboratory of Kidney Diseases, Chinese PLA General Hospital/PLA Medical School, Beijing, China."
            }
        ],
        "venue": "Modern Pathology",
        "year": 2017
    },
    "iRCzEdHI": {
        "id": "iRCzEdHI",
        "title": "Pure Small Cell Carcinoma of Prostate: A Report of 8 Cases.",
        "abstract": "Clinical characteristics, examination and treatment strategy of pure SCCP are very different from prostate adenocarcinoma. According to the data from published studies and from our studies, the average survival of patients receiving chemotherapy is longer than those who received other treatment modalities.",
        "keywords": [
            "Prognosis",
            "Chemotherapy",
            "Diagnosis\u00a0",
            "Prostate",
            "Small cell carcinoma"
        ],
        "authors": [
            {
                "name": "Yucong Zhang",
                "org": ""
            },
            {
                "name": "Wei Ouyang",
                "org": ""
            },
            {
                "name": "Guoliang Sun",
                "org": ""
            },
            {
                "name": "Beichen Ding",
                "org": ""
            },
            {
                "name": "Libin Yan",
                "org": ""
            },
            {
                "name": "Zhize Wang",
                "org": ""
            },
            {
                "name": "Wei Guan",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Zhiquan Hu",
                "org": ""
            },
            {
                "name": "Hua Xu",
                "org": ""
            },
            {
                "name": "Shaogang Wang",
                "org": ""
            },
            {
                "name": "Zhangqun Ye",
                "org": ""
            }
        ],
        "venue": "Urologia internationalis",
        "year": 2018
    },
    "Wx3AcXjx": {
        "id": "Wx3AcXjx",
        "title": "PD46-12 SETD2-MEDIATED LOSS OF MIR-10B DETERMINES MAP4K4 ACTIVATION IN RENAL CELL CARCINOMA",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Libin Yan",
                "org": "Wuhan, China, People's Republic of"
            },
            {
                "name": "Heng Li",
                "org": "Wuhan, China, People's Republic of"
            },
            {
                "name": "Yucong Zhang",
                "org": "Wuhan, China, People's Republic of"
            },
            {
                "name": "Hua Xu",
                "org": "Wuhan, China, People's Republic of"
            },
            {
                "name": "Zhangqun Ye",
                "org": "Wuhan, China, People's Republic of"
            }
        ],
        "venue": "The Journal of Urology",
        "year": 2018
    },
    "I0ntmlMd": {
        "id": "I0ntmlMd",
        "title": "Prognostic Value of Androgen Receptor Splice Variant 7 in the Treatment of Castration-resistant Prostate Cancer with Next generation Androgen Receptor Signal Inhibition: A Systematic Review and Meta-analysis",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China"
            },
            {
                "name": "Zhize Wang",
                "org": "Hubei Institute of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China"
            },
            {
                "name": "Kun Tang",
                "org": "Hubei Institute of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China"
            },
            {
                "name": "Hui Zhou",
                "org": "Hubei Institute of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China"
            },
            {
                "name": "Haoran Liu",
                "org": "Hubei Institute of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China"
            },
            {
                "name": "Libin Yan",
                "org": "Hubei Institute of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China"
            },
            {
                "name": "Wei Guan",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China"
            },
            {
                "name": "Ke Chen",
                "org": "Hubei Institute of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China"
            },
            {
                "name": "Hua Xu",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China"
            },
            {
                "name": "Zhangqun Ye",
                "org": "Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China"
            }
        ],
        "venue": "European urology focus",
        "year": 2017
    },
    "tDm7JgPz": {
        "id": "tDm7JgPz",
        "title": "Pure Small Cell Carcinoma of Prostate: A Report of 8 Cases.",
        "abstract": "Clinical characteristics, examination and treatment strategy of pure SCCP are very different from prostate adenocarcinoma. According to the data from published studies and from our studies, the average survival of patients receiving chemotherapy is longer than those who received other treatment modalities.",
        "keywords": [
            "Prognosis",
            "Chemotherapy",
            "Diagnosis\u00a0",
            "Prostate",
            "Small cell carcinoma"
        ],
        "authors": [
            {
                "name": "Yucong Zhang",
                "org": ""
            },
            {
                "name": "Wei Ouyang",
                "org": ""
            },
            {
                "name": "Guoliang Sun",
                "org": ""
            },
            {
                "name": "Beichen Ding",
                "org": ""
            },
            {
                "name": "Libin Yan",
                "org": ""
            },
            {
                "name": "Zhize Wang",
                "org": ""
            },
            {
                "name": "Wei Guan",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Zhiquan Hu",
                "org": ""
            },
            {
                "name": "Hua Xu",
                "org": ""
            },
            {
                "name": "Shaogang Wang",
                "org": ""
            },
            {
                "name": "Zhangqun Ye",
                "org": ""
            }
        ],
        "venue": "Urologia internationalis",
        "year": 2018
    },
    "SCvnHfAx": {
        "id": "SCvnHfAx",
        "title": "Microtubule stabilization promoted axonal regeneration and functional recovery after spinal root avulsion.",
        "abstract": "A spinal root avulsion injury disconnects spinal roots with the spinal cord. The rampant motoneuron death, inhibitory CNS/PNS transitional zone (TZ) for axonal regrowth and limited regeneration speed together lead to motor dysfunction. Microtubules rearrange to assemble a new growth cone and disorganized microtubules underline regeneration failure. It has been shown that microtubule-stabilizing drug, Epothilone B, enhanced axonal regeneration and attenuated fibrotic scaring after spinal cord injury. Here, we are reporting that after spinal root avulsion+ re-implantation in adult rats, EpoB treatment improved motor functional recovery and potentiated electrical responses of motor units. It facilitated axons to cross the TZ and promoted more and bigger axons in the peripheral nerve. Neuromuscular junctions were reformed with better preserved postsynaptic structure, and muscle atrophy was prevented by EpoB administration. Our study showed that EpoB was a promising therapy for promoting axonal regeneration after peripheral nerve injury.",
        "keywords": [
            "Epothilone B",
            "intrinsic regrowth capability",
            "motoneurons",
            "peripheral nerve regeneration"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": "School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, the University of Hong Kong, L1-39, 21 Sassoon Road, Pokfulam, Hong Kong SAR, China."
            },
            {
                "name": "Wutian Wu",
                "org": "Joint Laboratory of Jinan University and the University of Hong Kong, GHM Institute of CNS Regeneration, Jinan University, Guangzhou, China."
            }
        ],
        "venue": "The European journal of neuroscience",
        "year": 2017
    },
    "YzRWM5cz": {
        "id": "YzRWM5cz",
        "title": "Targeting proteoglycan receptor PTP\u03c3 restores sensory function after spinal cord dorsal root injury by activation of Erks/CREB signaling pathway.",
        "abstract": "Dorsal root injury commonly results in irreversible loss of sensory functions because of the limited intrinsic regenerative capacity of adult sensory axons and the growth-inhibitory environment at the dorsal root entry zone (DREZ) between the dorsal root and the spinal cord. Chondroitin sulfate proteoglycans (CSPGs) are the dominant suppressors of axonal regeneration, acting via neuronal receptors including protein tyrosine phosphatase-\u03c3 (PTP\u03c3). ISP (Intracellular Sigma Peptide) is a small peptide mimetic of the PTP\u03c3 wedge region that has been developed to target PTP\u03c3 and relieve CSPG inhibition. Extracellular regulated kinases (Erks) and cAMP response element binding protein (CREB) are signaling molecules downstream of CSPGs and PTP\u03c3; they are expressed in neurons and essential for axon growth. In this study, we observed that ISP administration could promote sensory function restoration in adult rats after dorsal spinal root crush injury. Our results show that systemic ISP administration would not only significantly increase sensory axon regeneration and functional recovery, but also activate Erk and CREB signaling pathway. Furthermore, ISP has also been verified to increase dorsal root ganglion axonal remyelination in vitro. These results suggest that modulation of PTP\u03c3 by ISP represents a promising therapeutic strategy for sensory neuronal injuries.",
        "keywords": [
            "Axon regeneration",
            "Dorsal root crush",
            "ISP",
            "PTP\u03c3",
            "Sensory refunction"
        ],
        "authors": [
            {
                "name": "Min Yao",
                "org": "School of Biomedical Sciences, The University of Hong Kong, Hong Kong SAR, 999077, China; Department of Surgery, The University of Hong Kong, Hong Kong SAR, 999077, China."
            },
            {
                "name": "Haitao Sun",
                "org": "School of Biomedical Sciences, The University of Hong Kong, Hong Kong SAR, 999077, China; The National Key Clinical Specialty, The Engineering Technology Research Center of Education Ministry of China, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, Department of Neurosurgery, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, China."
            },
            {
                "name": "Qiuju Yuan",
                "org": "School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, 999077, China."
            },
            {
                "name": "Ning Li",
                "org": "Department of Surgery, The University of Hong Kong, Hong Kong SAR, 999077, China."
            },
            {
                "name": "Heng Li",
                "org": "School of Biomedical Sciences, The University of Hong Kong, Hong Kong SAR, 999077, China."
            },
            {
                "name": "Yinjuan Tang",
                "org": "Department of Basic Medicine Sciences, Xiangnan University, Chenzhou, 423000, Hunan Province, China."
            },
            {
                "name": "Gilberto Kk Leung",
                "org": "Department of Surgery, The University of Hong Kong, Hong Kong SAR, 999077, China; Guangdong-Hongkong-Macau Institute of CNS Regeneration (GHMICR), Jinan University, Guangzhou, 510632, China. Electronic address: gilberto@hkucc.hku.hk."
            },
            {
                "name": "Wutian Wu",
                "org": "School of Biomedical Sciences, The University of Hong Kong, Hong Kong SAR, 999077, China; Guangdong-Hongkong-Macau Institute of CNS Regeneration (GHMICR), Jinan University, Guangzhou, 510632, China; Re-Stem Biotechnology Co., Ltd, Suzhou, 215300, China. Electronic address: wtwu@hku.hk."
            }
        ],
        "venue": "Neuropharmacology",
        "year": 2018
    },
    "RU981ity": {
        "id": "RU981ity",
        "title": "Functional self-assembling peptide nanofiber hydrogel for peripheral nerve regeneration.",
        "abstract": "Peripheral nerves are fragile and easily damaged, usually resulting in nervous tissue loss, motor and sensory function loss. Advances in neuroscience and engineering have been significantly contributing to bridge the damage nerve and create permissive environment for axonal regrowth across lesions. We have successfully designed two self-assembling peptides by modifying RADA 16-I with two functional motifs IKVAV and RGD. Nanofiber hydrogel formed when combing the two neutral solutions together, defined as RADA 16-Mix that overcomes the main drawback of RADA16-I associated with low pH. In the present study, we transplanted the RADA 16-Mix hydrogel into the transected rat sciatic nerve gap and effect on axonal regeneration was examined and compared with the traditional RADA16-I hydrogel. The regenerated nerves were found to grow along the walls of the large cavities formed in the graft of RADA16-I hydrogel, while the nerves grew into the RADA 16-Mix hydrogel toward distal position. RADA 16-Mix hydrogel induced more axons regeneration and Schwann cells immigration than RADA16-I hydrogel, resulting in better functional recovery as determined by the gait-stance duration percentage and the formation of new neuromuscular junction structures. Therefore, our results indicated that the functional SAP RADA16-Mix nanofibrous hydrogel provided a better environment for peripheral nerve regeneration than RADA16-I hydrogel and could be potentially used in peripheral nerve injury repair.",
        "keywords": [
            "IKVAV",
            "Peripheral nerve regeneration",
            "RGD",
            "nanofibrous hydrogel",
            "self-assembling peptide"
        ],
        "authors": [
            {
                "name": "Xiaoli Wu",
                "org": "Department of Anatomy, School of Biomedical Science, LKS Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Hong Kong SAR, China."
            },
            {
                "name": "Liumin He",
                "org": "Department of Anatomy, School of Biomedical Science, LKS Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Hong Kong SAR, China; Department of Anatomy, School of Biomedical Science, LKS Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Hong Kong SAR, China."
            },
            {
                "name": "Wen Li",
                "org": "Department of Anatomy, School of Biomedical Science, LKS Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Hong Kong SAR, China."
            },
            {
                "name": "Heng Li",
                "org": "Department of Anatomy, School of Biomedical Science, LKS Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Hong Kong SAR, China."
            },
            {
                "name": "Wai-Man Wong",
                "org": "Department of Anatomy, School of Biomedical Science, LKS Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Hong Kong SAR, China."
            },
            {
                "name": "Seeram Ramakrishna",
                "org": "Joint Laboratory of Jinan University and the University of Hong Kong, GHM Institute of CNS Regeneration, Jinan University, 601 Huangpu Avenue West, Guangzhou, 510632, China; Department of Mechanical Engineering, Faculty of Engineering, Center for Nanofibers and Nanotechnology, National University of Singapore, 117576, Singapore, Singapore."
            },
            {
                "name": "Wutian Wu",
                "org": "Department of Anatomy, School of Biomedical Science, LKS Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Hong Kong SAR, China; State Key Laboratory of Brain and Cognitive Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, 21 Sassoon Road, Hong Kong SAR, China; Joint Laboratory of Jinan University and the University of Hong Kong, GHM Institute of CNS Regeneration, Jinan University, 601 Huangpu Avenue West, Guangzhou, 510632, China."
            }
        ],
        "venue": "Regenerative biomaterials",
        "year": 2017
    },
    "MsT3Sml8": {
        "id": "MsT3Sml8",
        "title": "Transplantation of Embryonic Spinal Cord Derived Cells Helps to Prevent Muscle Atrophy after Peripheral Nerve Injury.",
        "abstract": "Injuries to peripheral nerves are frequent in serious traumas and spinal cord injuries. In addition to surgical approaches, other interventions, such as cell transplantation, should be considered to keep the muscles in good condition until the axons regenerate. In this study, E14.5 rat embryonic spinal cord fetal cells and cultured neural progenitor cells from different spinal cord segments were injected into transected musculocutaneous nerve of 200-300 g female Sprague Dawley (SD) rats, and atrophy in biceps brachii was assessed. Both kinds of cells were able to survive, extend their axons towards the muscle and form neuromuscular junctions that were functional in electromyographic studies. As a result, muscle endplates were preserved and atrophy was reduced. Furthermore, we observed that the fetal cells had a better effect in reducing the muscle atrophy compared to the pure neural progenitor cells, whereas lumbar cells were more beneficial compared to thoracic and cervical cells. In addition, fetal lumbar cells were used to supplement six weeks delayed surgical repair after the nerve transection. Cell transplantation helped to preserve the muscle endplates, which in turn lead to earlier functional recovery seen in behavioral test and electromyography. In conclusion, we were able to show that embryonic spinal cord derived cells, especially the lumbar fetal cells, are beneficial in the treatment of peripheral nerve injuries due to their ability to prevent the muscle atrophy.",
        "keywords": [
            "axonal injury",
            "cell transplantation",
            "delayed nerve repair",
            "fetal neurons",
            "functional recovery",
            "muscle atrophy",
            "neural progenitor cells",
            "neuromuscular junctions",
            "peripheral nerve injury",
            "spinal cord derived cells"
        ],
        "authors": [
            {
                "name": "Carolin Ruven",
                "org": "School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Hong Kong, China. carolinr@hku.hk."
            },
            {
                "name": "Wen Li",
                "org": "School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Hong Kong, China. liwenhlb@gmail.com."
            },
            {
                "name": "Heng Li",
                "org": "School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Hong Kong, China. lornalih@gmail.com."
            },
            {
                "name": "Wai-Man Wong",
                "org": "School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Hong Kong, China. wmwonga@hku.hk."
            },
            {
                "name": "Wutian Wu",
                "org": "Guangdong Engineering Research Center of Stem Cell Storage and Clinical Application, Saliai Stem Cell Science and Technology, Guangzhou 510000, China. wtwu@hku.hk."
            }
        ],
        "venue": "International journal of molecular sciences",
        "year": 2017
    },
    "4QUZ3aOi": {
        "id": "4QUZ3aOi",
        "title": "Rationalisation and validation of an acrylamide-free procedure in three-dimensional histological imaging",
        "abstract": "Three-dimensional visualization of intact tissues is now being achieved by turning tissues transparent. CLARITY is a unique tissue clearing technique, which features the use of detergents to remove lipids from fixed tissues to achieve optical transparency. To preserve tissue integrity, an acrylamide-based hydrogel has been proposed to embed the tissue. In this study, we examined the rationale behind the use of acrylamide in CLARITY, and presented evidence to suggest that the omission of acrylamide-hydrogel embedding in CLARITY does not alter the preservation of tissue morphology and molecular information in fixed tissues. We therefore propose a novel and simplified workflow for formaldehyde-fixed tissue clearing, which will facilitate the laboratory implementation of this technique. Furthermore, we have investigated the basic tissue clearing process in detail and have highlighted some areas for targeted improvement of technologies essential for the emerging subject of three-dimensional histology.",
        "keywords": "",
        "authors": [
            {
                "name": "Hei Ming Lai",
                "org": "School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China"
            },
            {
                "name": "Hei Ming Lai",
                "org": "School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China"
            },
            {
                "name": "Alan King Lun Liu",
                "org": "School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China"
            },
            {
                "name": "Alan King Lun Liu",
                "org": "School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China"
            },
            {
                "name": "Wai-Lung Ng",
                "org": "Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom"
            },
            {
                "name": "John DeFelice",
                "org": "Neuropathology Unit, Division of Brain Sciences, Department of Medicine, Imperial College London, United Kingdom"
            },
            {
                "name": "Wing Sang Lee",
                "org": "Electron Microscope Unit, The University of Hong Kong, Pokfulam, Hong Kong SAR, China"
            },
            {
                "name": "Heng Li",
                "org": "School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China"
            },
            {
                "name": "Wen Li",
                "org": "School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China"
            },
            {
                "name": "Ho Man Ng",
                "org": "School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China"
            },
            {
                "name": "Raymond Chuen-Chung Chang",
                "org": "School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China"
            },
            {
                "name": "Bin Lin",
                "org": "School of Optometry, The Hong Kong Polytechnic University, Hung Hom, Hong Kong SAR, China"
            },
            {
                "name": "Wutian Wu",
                "org": "School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China"
            },
            {
                "name": "Steve M. Gentleman",
                "org": "Neuropathology Unit, Division of Brain Sciences, Department of Medicine, Imperial College London, United Kingdom"
            }
        ],
        "venue": "PLOS ONE",
        "year": 2016
    },
    "f5OCw09T": {
        "id": "f5OCw09T",
        "title": "Finite-Time Stability and Stabilization for Continuous Systems with Additive Time-Varying Delays.",
        "abstract": "This paper is centered on the problem of delay-dependent finite-time stability and stabilization for a class of continuous system with additive time-varying delays. Firstly, based on a new Lyapunov---Krasovskii-like function (LKLF), which splits the whole delay interval into some proper subintervals, a set of delay-dependent finite-time stability conditions, guaranteeing that the state of the system does not exceed a given threshold in fixed time interval, are derived in form of linear matrix inequalities. In particular, to obtain a less conservative result, we take the LKLF as a whole to examine its positive definite which can slack the requirements for Lyapunov matrices and reduce the loss information when estimating the bound of the function. Further, based on the results of finite-time stability, sufficient conditions for the existence of a state feedback finite-time controller, guaranteeing finite-time stability of the closed-loop system, are obtained and can be solved by using some standard numerical packages. Finally, some numerical examples are provided to demonstrate the less conservative and the effectiveness of the proposed design approach.",
        "keywords": "",
        "authors": [
            {
                "name": "Xiaogong Lin",
                "org": "College of Automation, Harbin Engineering University, Harbin, People's Republic of China 150001"
            },
            {
                "name": "Kun Liang",
                "org": "College of Automation, Harbin Engineering University, Harbin, People's Republic of China 150001"
            },
            {
                "name": "Heng Li",
                "org": "College of Automation, Harbin Engineering University, Harbin, People's Republic of China 150001"
            },
            {
                "name": "Yuzhao Jiao",
                "org": "College of Automation, Harbin Engineering University, Harbin, People's Republic of China 150001"
            },
            {
                "name": "Jun Nie",
                "org": "College of Automation, Harbin Engineering University, Harbin, People's Republic of China 150001"
            }
        ],
        "venue": "CSSP",
        "year": 2017
    },
    "ojjCxsXB": {
        "id": "ojjCxsXB",
        "title": "Nonlinear passive robust observer design for a DP system based on ACA",
        "abstract": "A nonlinear passive robust filtering method is described in this article to solve filtering and state estimation problems of ship dynamic positioning system (DPS) in slowly varying sea state. By augmenting a new state and utilizing acceleration feedback technology, the observer proposed in this paper will improve disturbance attenuation performance. The global stability and passivity of the observer are proved. The observer parameters are optimized off-line using ant colony algorithm (ACA). Results show that the present methodology works quite well for numerical examples.",
        "keywords": "",
        "authors": [
            {
                "name": "Xiaogong Lin",
                "org": "College of Automation, Harbin Engineering University, Harbin 150001, China"
            },
            {
                "name": "Heng Li",
                "org": "College of Automation, Harbin Engineering University, Harbin 150001, China"
            },
            {
                "name": "Kun Liang",
                "org": "College of Automation, Harbin Engineering University, Harbin 150001, China"
            },
            {
                "name": "Yuzhao Jiao",
                "org": "College of Automation, Harbin Engineering University, Harbin 150001, China"
            }
        ],
        "venue": "chinese control conference",
        "year": 2017
    },
    "KxKyifwA": {
        "id": "KxKyifwA",
        "title": "The variational Bayesian-variable structure filter for uncertain system with model imprecision and unknown measurement noise",
        "abstract": "Variable structure filter (VSF) is a robust filter for linear uncertain system. In order to remove the chattering caused by high-frequency gain switching of VSF, the smoothing boundary layer (SBL) has been introduced. And similar to Kalman filter, the optimal state estimation of VSF can be got at the optimal smoothing boundary layer (OSBL). However, in practical applications, the statistical characteristics of the measurement noise are unknown. It is difficult to obtain the exact solution of the OSBL which is related to the measurement noise covariance. On the other hand, it is considered that the variational Bayesian adaptive Kalman filter (VB-AKF) is an adaptive filter with noise estimator for linear system with unknown measurement noise covariance. Therefore this paper proposes a variational Bayesian-variable structure filter (VB-VSF), which can make full use of VB-AKFu0027s adaptive measurement noise estimation performance and the robustness of VSF. And the OSBL calculated from initial values is readjusted by the proposed VB-VSF algorithm. In this way, the calculated real OSBL can approach the theoretically OSBL. And the theoretically optimal state estimation can be obtained. In the end, the accuracy and the robustness of the proposed VB-VSF are verified through by simulation examples.",
        "keywords": "",
        "authors": [
            {
                "name": "Xiaogong Lin",
                "org": "School of Automation, Harbin Engineering University, 145 Nantong Street, Harbin, 150001, China"
            },
            {
                "name": "Yuzhao Jiao",
                "org": "School of Automation, Harbin Engineering University, 145 Nantong Street, Harbin, 150001, China"
            },
            {
                "name": "Heng Li",
                "org": "School of Automation, Harbin Engineering University, 145 Nantong Street, Harbin, 150001, China"
            },
            {
                "name": "Kun Liang",
                "org": "School of Automation, Harbin Engineering University, 145 Nantong Street, Harbin, 150001, China"
            }
        ],
        "venue": "chinese control conference",
        "year": 2017
    },
    "W6leQ8fX": {
        "id": "W6leQ8fX",
        "title": "Adaptive fuzzy output feedback stabilization control for the underactuated surface vessel",
        "abstract": "Abstract   This paper designs an adaptive fuzzy stabilization controller for the underactuated surface vessel in the presence of unknown time varying environment disturbances and input saturation. By combining adaptive fuzzy system and auxiliary dynamic function, a stabilization control scheme is developed via vectorial backstepping technique and Lyapunov direct method. To begin with, based on the diffeomorphism equivalent transformation, the stabilization problem of underactuated surface vessel can be transformed into the stabilization analysis of two subsystem. Further, the adaptive fuzzy system is employed to approximate the uncertain term induced by the unknown time varying environment disturbances in the control law. In particularly, an auxiliary dynamic function is exploited to deal with the input saturation. It is proved that the proposed adaptive fuzzy output feedback controller can stabilize the vessel to desired equilibrium origin, while guaranteeing the uniform ultimate boundedness of all closed loop signals in the underactuated system. Finally, simulation results are given to demonstrate the effectiveness of the proposed control approach.",
        "keywords": "",
        "authors": [
            {
                "name": "Xiaogong Lin",
                "org": ""
            },
            {
                "name": "Jun Nie",
                "org": "College of Automation, Harbin Engineering University, Harbin 150001, China"
            },
            {
                "name": "Yuzhao Jiao",
                "org": "College of Automation, Harbin Engineering University, Harbin 150001, China"
            },
            {
                "name": "Kun Liang",
                "org": "College of Automation, Harbin Engineering University, Harbin 150001, China"
            },
            {
                "name": "Heng Li",
                "org": "College of Automation, Harbin Engineering University, Harbin 150001, China"
            }
        ],
        "venue": "Applied Ocean Research",
        "year": 2018
    },
    "VJzw8U70": {
        "id": "VJzw8U70",
        "title": "Nonlinear adaptive fuzzy output-feedback controller design for dynamic positioning system of ships",
        "abstract": "Abstract   This paper develops a nonlinear adaptive fuzzy output feedback controller for dynamic positioning (DP) system of ships in the presence of unmeasured states of ships, unknown dynamic model parameters, unknown time varying environment disturbances and input saturation. It is the first time that all the conditions above are simultaneously dealt with in the DP control design. By combining adaptive fuzzy system and auxiliary dynamic system, a control scheme with high-gain observer is developed via vectorial backstepping method. It is proved that the proposed nonlinear adaptive fuzzy output feedback controller can maintain the ship at desired position and heading with arbitrary accuracy, while guaranteeing the uniform ultimate boundedness of all closed loop signals in the DP system. Finally, simulations are carried on a supply ship to demonstrate the effectiveness of the proposed control approach.",
        "keywords": "",
        "authors": [
            {
                "name": "Xiaogong Lin",
                "org": ""
            },
            {
                "name": "Jun Nie",
                "org": "College of Automation, Harbin Engineering University, Harbin, 150001, China"
            },
            {
                "name": "Yuzhao Jiao",
                "org": "College of Automation, Harbin Engineering University, Harbin, 150001, China"
            },
            {
                "name": "Kun Liang",
                "org": "College of Automation, Harbin Engineering University, Harbin, 150001, China"
            },
            {
                "name": "Heng Li",
                "org": "College of Automation, Harbin Engineering University, Harbin, 150001, China"
            }
        ],
        "venue": "Ocean Engineering",
        "year": 2018
    },
    "PQQMzrBc": {
        "id": "PQQMzrBc",
        "title": "Robust Finite-Time H-Infinity Control with Transients for Dynamic Positioning Ship Subject to Input Delay",
        "abstract": "This paper presents the problem of robust finite-time  control with transients for ocean surface vessels equipped with dynamic positioning (DP) system in presence of input delay. The main objective of this work is to design a finite-time  state feedback controller, which ensures that all states of ship do not exceed a given threshold over a fixed time interval, with better robustness and transient performance subject to time-varying disturbance. Based on a novel augmented Lyapunov-Krasovskii-like function (LKLF) with triple integral terms and a method combining the Wirtinger inequality and reciprocally convex approach, a less conservative result is derived. In particular, an  performance index with nonzero initial condition is introduced to attenuate the overconservatism caused by the assumption of zero initial condition and enhance the transient performance of ship subject to external disturbance. More precisely, the controller gain matrix for the DP system can be achieved by solving the linear matrix inequalities (LMIs), which can be easily facilitated by using some standard numerical packages. Finally, a numerical simulation for a ship is proposed to verify the effectiveness and less conservatism of the controller we designed.",
        "keywords": "",
        "authors": [
            {
                "name": "Xiaogong Lin",
                "org": ""
            },
            {
                "name": "Kun Liang",
                "org": "College of Automation, Harbin Engineering University, Harbin, China"
            },
            {
                "name": "Heng Li",
                "org": "College of Automation, Harbin Engineering University, Harbin, China"
            },
            {
                "name": "Yuzhao Jiao",
                "org": "College of Automation, Harbin Engineering University, Harbin, China"
            },
            {
                "name": "Jun Nie",
                "org": "College of Automation, Harbin Engineering University, Harbin, China"
            }
        ],
        "venue": "Mathematical Problems in Engineering",
        "year": 2018
    },
    "GLmrtRK6": {
        "id": "GLmrtRK6",
        "title": "Fault-Tolerant Supervisory Control for Dynamic Positioning of Ships",
        "abstract": "A fault-tolerant supervisory control method for dynamic positioning of ships with actuator failures and sensor failures is presented in this paper. Unlike the traditional fault detection and control, fault detection and fault-tolerant controller are designed as a unit in this paper through a supervisor. By introducing a nonlinear estimation error and virtual controller, the sensor failures are separated from the actuator failures in the supervisory control system. It guarantees that the detectability property and matching property of the switched system are satisfied. Firstly, a new extended state observer is designed to match the models of different actuator failures. Secondly, by introducing a virtual controller, the detectability property of the switched system is guaranteed. Finally, a nonlinear estimation error operator is used in the designing of switching logic to guarantee stability of the closed-loop system with sensor failures. When sensor failures and actuator failures occur, we show that all the states of the closed-loop system are guaranteed to be bounded. The effectiveness of the fault-tolerant control is verified by simulation experiments.",
        "keywords": "",
        "authors": [
            {
                "name": "Xiaogong Lin",
                "org": "College of Automation, Harbin Engineering University, Harbin 150001, China"
            },
            {
                "name": "Heng Li",
                "org": "College of Automation, Harbin Engineering University, Harbin 150001, China"
            },
            {
                "name": "Kun Liang",
                "org": "College of Automation, Harbin Engineering University, Harbin 150001, China"
            },
            {
                "name": "Jun Nie",
                "org": "College of Automation, Harbin Engineering University, Harbin 150001, China"
            },
            {
                "name": "Juan Li",
                "org": "College of Automation, Harbin Engineering University, Harbin 150001, China"
            }
        ],
        "venue": "Mathematical Problems in Engineering",
        "year": 2019
    },
    "geq8qKIl": {
        "id": "geq8qKIl",
        "title": "Towards just-in-time suggestions for log changes.",
        "abstract": "Software developers typically insert logging statements in their source code to record runtime information. However, providing proper logging statements remains a challenging task. Prior approaches automatically enhance logging statements, as a post-implementation process. Such automatic approaches do not take into account developers' domain knowledge; nevertheless, developers usually need to carefully design the logging statements since logs are a rich source about the field operation of a software system. The goals of this paper include: i) understanding the reasons for log changes; and ii) proposing an approach that can provide developers with log change suggestions as soon as they commit a code change, which we refer to as \\\"just-in-time\\\" suggestions for log changes. In particular, we derive a set of measures based on manually examining the reasons for log changes and our experiences. We use these measures as explanatory variables in random forest classifiers to model whether a code commit requires log changes. These classifiers can provide just-in-time suggestions for log changes. We perform a case study on four open source projects: Hadoop, Directory Server, Commons HttpClient, and Qpid. We find that: (i) The reasons for log changes can be grouped along four categories: block change, log improvement, dependence-driven change, and logging issue; (ii) our random forest classifiers can effectively suggest whether a log change is needed: the classifiers that are trained from within-project data achieve a balanced accuracy of 0.76 to 0.82, and the classifiers that are trained from cross-project data achieve a balanced accuracy of 0.76 to 0.80; (iii) the characteristics of code changes in a particular commit and the current snapshot of the source code are the most influential factors for determining the likelihood of a log change in a commit.",
        "keywords": [
            "Software logs",
            "Log improvement",
            "Mining software repositories"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": "Software Analysis and Intelligence Lab (SAIL), Queen's University, Kingston, Canada"
            },
            {
                "name": "Weiyi Shang",
                "org": "Department of Computer Science and Software Engineering, Concordia University, Montreal, Canada"
            },
            {
                "name": "Ying Zou",
                "org": "Department of Electrical and Computer Engineering, Queen's University, Kingston, Canada"
            },
            {
                "name": "Ahmed E. Hassan",
                "org": "Software Analysis and Intelligence Lab (SAIL), Queen's University, Kingston, Canada"
            }
        ],
        "venue": "Empirical Software Engineering",
        "year": 2017
    },
    "yVCAyLJo": {
        "id": "yVCAyLJo",
        "title": "Which log level should developers choose for a new logging statement?",
        "abstract": "Logging statements are used to record valuable runtime information about applications. Each logging statement is assigned a log level such that users can disable some verbose log messages while allowing the printing of other important ones. However, prior research finds that developers often have difficulties when determining the appropriate level for their logging statements. In this paper, we propose an approach to help developers determine the appropriate log level when they add a new logging statement. We analyze the development history of four open source projects (Hadoop, Directory Server, Hama, and Qpid), and leverage ordinal regression models to automatically suggest the most appropriate level for each newly-added logging statement. First, we find that our ordinal regression model can accurately suggest the levels of logging statements with an AUC (area under the curve; the higher the better) of 0.75 to 0.81 and a Brier score (the lower the better) of 0.44 to 0.66, which is better than randomly guessing the appropriate log level (with an AUC of 0.50 and a Brier score of 0.80 to 0.83) or naively guessing the log level based on the proportional distribution of each log level (with an AUC of 0.50 and a Brier score of 0.65 to 0.76). Second, we find that the characteristics of the containing block of a newly-added logging statement, the existing logging statements in the containing source code file, and the content of the newly-added logging statement play important roles in determining the appropriate log level for that logging statement.",
        "keywords": [
            "Logging statement",
            "Log level",
            "Ordinal regression model"
        ],
        "authors": [
            {
                "name": "Heng Li",
                "org": "Software Analysis and Intelligence Lab (SAIL), Queen's University, Kingston, Canada"
            },
            {
                "name": "Weiyi Shang",
                "org": "Department of Computer Science and Software Engineering, Concordia University, Montreal, Canada"
            },
            {
                "name": "Ahmed E. Hassan",
                "org": "Software Analysis and Intelligence Lab (SAIL), Queen's University, Kingston, Canada"
            }
        ],
        "venue": "Empirical Software Engineering",
        "year": 2017
    },
    "yR9FBbl0": {
        "id": "yR9FBbl0",
        "title": "Towards just-in-time suggestions for log changes (journal-first abstract).",
        "abstract": "This is an extended abstract of a paper published in the Empirical Software Engineering journal. The original paper is communicated by Arie van Deursen. The paper empirically studied why developers make log changes and proposed an automated approach to provide developers with log change suggestions as soon as they commit a code change. Through a case study on four open source projects, we found that the reasons for log changes can be grouped along four categories: block change, log improvement, dependence-driven change, and logging issue. We also found that our automated approach can effectively suggest whether a log change is needed for a code change with a balanced accuracy of 0.76 to 0.82.",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Weiyi Shang",
                "org": "Department of Computer Science and Software Engineering, Concordia University, Canada"
            },
            {
                "name": "Ying Zou",
                "org": "Department of Electrical and Computer Engineering, Queen's University, Canada"
            },
            {
                "name": "Ahmed E. Hassan",
                "org": "Software Analysis and Intelligence Lab (SAIL), Queen's University, Canada"
            }
        ],
        "venue": "SANER",
        "year": 2018
    },
    "cESbJzEI": {
        "id": "cESbJzEI",
        "title": "Which log level should developers choose for a new logging statement? (journal-first abstract).",
        "abstract": "This is an extended abstract of a paper published in the Empirical Software Engineering journal. The original paper is communicated by Mark Grechanik. The paper empirically studied how developers assign log levels to their logging statements and proposed an automated approach to help developers determine the most appropriate log level when they add a new logging statement. We analyzed the development history of four open source projects (Hadoop, Directory Server, Hama, and Qpid). We found that our automated approach can accurately suggest the levels of logging statements with an AUC of 0.75 to 0.81. We also found that the characteristics of the containing block of a newly-added logging statement, the existing logging statements in the containing source code file, and the content of the newly-added logging statement play important roles in determining the appropriate log level for that logging statement.",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Weiyi Shang",
                "org": "Department of Computer Science and Software Engineering, Concordia University, Canada"
            },
            {
                "name": "Ahmed E. Hassan",
                "org": "Software Analysis and Intelligence Lab (SAIL), Queen's University, Canada"
            }
        ],
        "venue": "SANER",
        "year": 2018
    },
    "JOAqAYeR": {
        "id": "JOAqAYeR",
        "title": "Improving the testing efficiency of selenium-based load tests",
        "abstract": "Web applications must be load tested to analyze their behavior under various load conditions. Typically, these load tests are automated using protocol-level HTTP requests (e.g., using JMeter). However, there are several disadvantages to using protocol-level requests for load tests. For example, protocol-level requests are only partially representative of the true usage of a web application, as the web application is not actually executed in a browser. It can be difficult to abstract complex behavior, such as a login sequence, into requests without executing the application. Browser-based load testing can be used as an alternative to protocol-level requests. Using a browser-based testing framework, such as Selenium, tests can be executed more realistically --- inside a browser. Unfortunately, because a browser instance must be started to conduct a test, browser-based testing has a high performance overhead which limits its applicability for load tests. In this paper, we propose an approach for reducing the performance overhead of running Selenium-based load tests. Our approach shares browser instances between test user instances, thereby reducing the performance overhead that is introduced by launching many browser instances during the execution of a test. Our experimental results show that our approach can significantly increase the number of user instances that can be tested on a test machine without overloading the load driver. Our approach and the experiences that we share in this paper can help software practitioners improve the efficiency of their own Selenium-based load tests.\n\n",
        "keywords": "",
        "authors": [
            {
                "name": "Shahnaz M. Shariff",
                "org": "Queen's University"
            },
            {
                "name": "Heng Li",
                "org": "Queen's University"
            },
            {
                "name": "Cor-Paul Bezemer",
                "org": "University of Alberta"
            },
            {
                "name": "Ahmed E. Hassan",
                "org": "Queen's University"
            },
            {
                "name": "Thanh H. D. Nguyen",
                "org": "BlackBerry, Canada"
            },
            {
                "name": "Parminder Flora",
                "org": "BlackBerry, Canada"
            }
        ],
        "venue": "Proceedings of the 14th International Workshop on Automation of Software Test",
        "year": 2019
    },
    "H2jF9u9p": {
        "id": "H2jF9u9p",
        "title": "Adopting autonomic computing capabilities in existing large-scale systems: an industrial experience report.",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Tse-Hsun (Peter) Chen",
                "org": ""
            },
            {
                "name": "Ahmed E. Hassan",
                "org": ""
            },
            {
                "name": "Mohamed N. Nasser",
                "org": ""
            },
            {
                "name": "Parminder Flora",
                "org": ""
            }
        ],
        "venue": "ICSE (SEIP)",
        "year": 2018
    },
    "Oixrim2l": {
        "id": "Oixrim2l",
        "title": "Adopting Autonomic Computing Capabilities in Existing Large-Scale Systems",
        "abstract": "In current DevOps practice, developers are responsible for the operation and maintenance of software systems. However, the human costs for the operation and maintenance grow fast along with the increasing functionality and complexity of software systems. Autonomic computing aims to reduce or eliminate such human intervention. However, there are many existing large systems that did not consider autonomic computing capabilities in their design. Adding autonomic computing capabilities to these existing systems is particularly challenging, because of 1) the significant amount of efforts that are required for investigating and refactoring the existing code base, 2) the risk of adding additional complexity, and 3) the difficulties for allocating resources while developers are busy adding core features to the system. In this paper, we share our industrial experience of re-engineering autonomic computing capabilities to an existing large-scale software system. Our autonomic computing capabilities effectively reduce human intervention on performance configuration tuning and significantly improve system performance. In particular, we discuss the challenges that we encountered and the lessons that we learned during this re-engineering process. For example, in order to minimize the change impact to the original system, we use a variety of approaches (e.g., aspect-oriented programming) to separate the concerns of autonomic computing from the original behaviour of the system. We also share how we tested such autonomic computing capabilities under different conditions, which has never been discussed in prior work. As there are numerous large-scale software systems that still require expensive human intervention, we believe our experience provides valuable insights to software practitioners who wish to add autonomic computing capabilities to these existing large-scale software systems.",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Tse-Hsun Chen",
                "org": ""
            },
            {
                "name": "Ahmed E. Hassan",
                "org": "Queen's University"
            },
            {
                "name": "Mohamed N. Nasser",
                "org": "BlackBerry Limited"
            },
            {
                "name": "Parminder Flora",
                "org": "BlackBerry Limited"
            }
        ],
        "venue": "international conference on software engineering",
        "year": 2017
    },
    "zSqwuNJr": {
        "id": "zSqwuNJr",
        "title": "Adopting autonomic computing capabilities in existing large-scale systems: an industrial experience report.",
        "abstract": "In current DevOps practice, developers are responsible for the operation and maintenance of software systems. However, the human costs for the operation and maintenance grow fast along with the increasing functionality and complexity of software systems. Autonomic computing aims to reduce or eliminate such human intervention. However, there are many existing large systems that did not consider autonomic computing capabilities in their design. Adding autonomic computing capabilities to these existing systems is particularly challenging, because of 1) the significant amount of efforts that are required for investigating and refactoring the existing code base, 2) the risk of adding additional complexity, and 3) the difficulties for allocating resources while developers are busy adding core features to the system. In this paper, we share our industrial experience of re-engineering autonomic computing capabilities to an existing large-scale software system. Our autonomic computing capabilities effectively reduce human intervention on performance configuration tuning and significantly improve system performance. In particular, we discuss the challenges that we encountered and the lessons that we learned during this re-engineering process. For example, in order to minimize the change impact to the original system, we use a variety of approaches (e.g., aspect-oriented programming) to separate the concerns of autonomic computing from the original behaviour of the system. We also share how we tested such autonomic computing capabilities under different conditions, which has never been discussed in prior work. As there are numerous large-scale software systems that still require expensive human intervention, we believe our experience provides valuable insights to software practitioners who wish to add autonomic computing capabilities to these existing large-scale software systems.",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Tse-Hsun (Peter) Chen",
                "org": "Concordia University, Canada"
            },
            {
                "name": "Ahmed E. Hassan",
                "org": "Queen's University, Canada"
            },
            {
                "name": "Mohamed N. Nasser",
                "org": "BlackBerry, Canada"
            },
            {
                "name": "Parminder Flora",
                "org": "BlackBerry, Canada"
            }
        ],
        "venue": "ICSE (SEIP)",
        "year": 2018
    },
    "f4AQJ2St": {
        "id": "f4AQJ2St",
        "title": "Undifferentiated sinonasal malignant melanoma: A case report.",
        "abstract": "Undifferentiated sinonasal malignant melanoma (MM) is a rare type of tumor, which can be easily misdiagnosed. The present study reports a 41-year-old male patient who presented with a 4-day history of epistaxis. Clinical examination and radiological imaging lead to the detection of a mass in the right sinonasal region. Histopathological examination revealed that the mass was composed of malignant epithelioid cells arranged in nests and sheets. These cells displayed a hemangiopericytoma-like pattern with antler-like branching vessels. Immunohistochemical staining revealed that the tumor cells exhibited negative expression of melanocytic markers. This increased the difficulty of distinguishing undifferentiated MM from other malignant tumors located in the sinonasal area, particularly undifferentiated nasopharyngeal carcinoma. The diagnosis of undifferentiated MM was determined by ultrastructures, including the mature melanosomes and premelanosomes, in tumor cells by transmission electron microscopy. The present study suggests that the analysis of cancer stem cell marker and vasculogenic mimicry may be an important auxiliary tool for the diagnosis of MM.",
        "keywords": [
            "diagnosis",
            "melanoma",
            "pathology",
            "undifferentiated"
        ],
        "authors": [
            {
                "name": "Jun Du",
                "org": "Department of Pathology, Anhui Provincial Hospital, Hefei, Anhui 230001, P.R. China."
            },
            {
                "name": "Liang-Liang Huang",
                "org": "Department of Pathology, Anhui Provincial Hospital, Hefei, Anhui 230001, P.R. China."
            },
            {
                "name": "Ao Xu",
                "org": "Department of Pathology, Anhui Provincial Hospital, Hefei, Anhui 230001, P.R. China."
            },
            {
                "name": "An-Li Zhang",
                "org": "Department of Pathology, Anhui Provincial Hospital, Hefei, Anhui 230001, P.R. China."
            },
            {
                "name": "Xue Kong",
                "org": "Department of Pathology, Anhui Provincial Hospital, Hefei, Anhui 230001, P.R. China."
            },
            {
                "name": "Min Ding",
                "org": "Department of Pathology, Anhui Provincial Hospital, Hefei, Anhui 230001, P.R. China."
            },
            {
                "name": "Wen Hu",
                "org": "Department of Pathology, Anhui Provincial Hospital, Hefei, Anhui 230001, P.R. China."
            },
            {
                "name": "Zhen-Li Guo",
                "org": "Department of Pathology, Anhui Provincial Hospital, Hefei, Anhui 230001, P.R. China."
            },
            {
                "name": "Wen Zhong",
                "org": "Department of Pathology, Anhui Provincial Hospital, Hefei, Anhui 230001, P.R. China."
            },
            {
                "name": "Si-Bai Sun",
                "org": "Department of Pathology, Anhui Provincial Hospital, Hefei, Anhui 230001, P.R. China."
            },
            {
                "name": "Heng Li",
                "org": "Department of Pathology, Anhui Provincial Hospital, Hefei, Anhui 230001, P.R. China."
            },
            {
                "name": "Jie Chen",
                "org": "Department of Pathology, Anhui Provincial Hospital, Hefei, Anhui 230001, P.R. China."
            },
            {
                "name": "Qian Shen",
                "org": "Department of Pathology, Anhui Provincial Hospital, Hefei, Anhui 230001, P.R. China."
            },
            {
                "name": "Lu-Lu Xu",
                "org": "Department of Pathology, Anhui Provincial Hospital, Hefei, Anhui 230001, P.R. China."
            },
            {
                "name": "Hai-Bo Wu",
                "org": "Department of Pathology, Anhui Provincial Hospital, Hefei, Anhui 230001, P.R. China."
            }
        ],
        "venue": "Oncology letters",
        "year": 2018
    },
    "KZzOrPpy": {
        "id": "KZzOrPpy",
        "title": "An experimental study of nitrogen gas influence on the 443 ferritic stainless steel joints by double-shielded welding",
        "abstract": "This study addressed the comparison of microstructures and mechanical properties of gas tungsten arc welding (GTAW) of 443 super pure ferritic stainless steel which are protected by three different kinds of shielding gas during welding process: pure argon, argon in the inner layer combined with nitrogen in the outer layer (simple double-layer gas), and argon-5 %nitrogen in the inner layer combined with nitrogen in the outer layer (mixed double-layer gas). As a result, in the center of the welds protected by nitrogen and argon, it formed equiaxed grains which achieving the purpose of grain refinement, while there were all columnar grains in the weld protected by pure argon. The experimental results showed that the depth/width ratio of the welds shielded by simple double-layer gas had been increased. Additionally, with the addition of nitrogen in the shielding gas, the hardness and impact toughness of the weld metal and heat-affected zone (HAZ) were improved when the heat input was the same. The relationships between microstructures and mechanical properties of 443 ferritic stainless steel joints were studied by optical microscope and scanning electron microscope combined with energy-dispersive spectrometer.",
        "keywords": "",
        "authors": [
            {
                "name": "Yong Zheng",
                "org": "Taiyuan University of Technology"
            },
            {
                "name": "Yichen Wang",
                "org": "Taiyuan University of Technology"
            },
            {
                "name": "Heng Li",
                "org": "Taiyuan University of Technology"
            },
            {
                "name": "Wenqing Xing",
                "org": "Taiyuan University of Technology"
            },
            {
                "name": "Xin-ye Yu",
                "org": "Taiyuan University of Technology"
            },
            {
                "name": "Peng Dong",
                "org": "Taiyuan University of Technology"
            },
            {
                "name": "Wenxian Wang",
                "org": ""
            },
            {
                "name": "Guangwei Fan",
                "org": "Taiyuan Iron and Steel (Group) Company Limited"
            },
            {
                "name": "Jie Lian",
                "org": "Taiyuan Iron and Steel (Group) Company Limited"
            },
            {
                "name": "Min Ding",
                "org": "Taiyuan University of Technology"
            }
        ],
        "venue": "The International Journal of Advanced Manufacturing Technology",
        "year": 2016
    },
    "ZmWjn8Wi": {
        "id": "ZmWjn8Wi",
        "title": "Dramatically enhanced impact toughness in welded ultra-ferritic stainless steel by additional nitrogen gas in Ar-based shielding gas",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Wenqing Xing",
                "org": ""
            },
            {
                "name": "Xin-ye Yu",
                "org": ""
            },
            {
                "name": "Wei Zuo",
                "org": ""
            },
            {
                "name": "Le Ma",
                "org": ""
            },
            {
                "name": "Peng Dong",
                "org": ""
            },
            {
                "name": "Wenxian Wang",
                "org": ""
            },
            {
                "name": "Guangwei Fan",
                "org": ""
            },
            {
                "name": "Jie Lian",
                "org": ""
            },
            {
                "name": "Min Ding",
                "org": ""
            }
        ],
        "venue": "Journal of Materials Research",
        "year": 2016
    },
    "fs3LIEoV": {
        "id": "fs3LIEoV",
        "title": "Effect of nano Al2O3 additions on the interfacial behavior and mechanical properties of eutectic Sn-9Zn solder on low temperature wetting and soldering of 6061 aluminum alloys",
        "abstract": "Abstract   In this study, an addition of Al 2 O 3  nano-particles with a content in the range of 0\u20131\u00a0wt% to Sn-9Zn eutectic solder, were examined in order to understand the effects of Al 2 O 3  additions as the particulate reinforcement to the melting point, wettability, microstructure, interface morphology and hardness as well as mechanical properties of soldering 6061 aluminum alloys. Here, an approach to prepare a composite solder by adding Al 2 O 3  nano-particles to the molten Sn\u20139Zn solder alloy was developed. In the soldered joint using Sn\u20139Zn solders, there is a solution layer of Al 8 ZnSn 4  located at the interface. Due to the addition of Al 2 O 3  nano-particles, the scallop-shaped solid solution layer was changed into a flat layer, and its thickness was reduced. In the microstructure of the composite solder containing 1\u00a0wt% Al 2 O 3  nano-particles, the fine acicular-shaped Sn-Zn eutectic structure and Al 2 O 3  nano-particles were found to be distributed in the \u03b2-Sn matrix. These changes in the interfaces and the microstructure, leading to the improvement of wettability, mechanical properties and hardness of the composite solder.",
        "keywords": "",
        "authors": [
            {
                "name": "Wenqing Xing",
                "org": "Taiyuan University of Technology, College of Material Science and Technology, Taiyuan 030024, China"
            },
            {
                "name": "Xin-ye Yu",
                "org": "Taiyuan University of Technology, College of Material Science and Technology, Taiyuan 030024, China"
            },
            {
                "name": "Heng Li",
                "org": "Taiyuan University of Technology, College of Material Science and Technology, Taiyuan 030024, China"
            },
            {
                "name": "Le Ma",
                "org": "Taiyuan University of Technology, College of Material Science and Technology, Taiyuan 030024, China"
            },
            {
                "name": "Wei Zuo",
                "org": "Taiyuan University of Technology, College of Material Science and Technology, Taiyuan 030024, China"
            },
            {
                "name": "Peng Dong",
                "org": "Taiyuan University of Technology, College of Material Science and Technology, Taiyuan 030024, China"
            },
            {
                "name": "Wenxian Wang",
                "org": ""
            },
            {
                "name": "Min Ding",
                "org": "Taiyuan University of Technology, College of Material Science and Technology, Taiyuan 030024, China"
            }
        ],
        "venue": "Journal of Alloys and Compounds",
        "year": 2017
    },
    "ajdqutHn": {
        "id": "ajdqutHn",
        "title": "Microstructure and mechanical properties of Sn-9Zn-xAl2O3 nanoparticles (x=0\u20131) lead-free solder alloy: First-principles calculation and experimental research",
        "abstract": "Abstract   This paper studies microstructure and mechanical properties of Sn-9Zn-x Al 2 O 3  nanoparticles (x=0\u20131) lead-free solder alloy. The interface structure, interface energy and electronic properties of Al 2 O 3 /Sn9Zn interface are investigated by first-principle calculation. On the experimental part, in comparison with the plain Sn-9Zn solder, the Al 2 O 3  nanoparticles incorporated into the solder matrix can inhibit the growth of coarse dendrite Sn-Zn eutectic structure and refine grains of the composite solders during the solidification process of the alloys. Moreover, the microhardness and average tensile strength of the solders with addition of Al 2 O 3  nanoparticles increased with the increasing weight percentages of Al 2 O 3  nanoparticles. These improved mechanical properties can be attributed to the microstructure developments and the dispersed Al 2 O 3  nanoparticles.",
        "keywords": "",
        "authors": [
            {
                "name": "Wen-qing Xing",
                "org": "Taiyuan University of Technology, College of Material Science and Technology, Taiyuan 030024, China"
            },
            {
                "name": "Xin-ye Yu",
                "org": "Taiyuan University of Technology, College of Material Science and Technology, Taiyuan 030024, China"
            },
            {
                "name": "Heng Li",
                "org": "Taiyuan University of Technology, College of Material Science and Technology, Taiyuan 030024, China"
            },
            {
                "name": "Le Ma",
                "org": "Taiyuan University of Technology, College of Material Science and Technology, Taiyuan 030024, China"
            },
            {
                "name": "Wei Zuo",
                "org": "Taiyuan University of Technology, College of Material Science and Technology, Taiyuan 030024, China"
            },
            {
                "name": "Peng Dong",
                "org": "Taiyuan University of Technology, College of Material Science and Technology, Taiyuan 030024, China"
            },
            {
                "name": "Wen-xian Wang",
                "org": "Taiyuan University of Technology, College of Material Science and Technology, Taiyuan 030024, China"
            },
            {
                "name": "Min Ding",
                "org": "Taiyuan University of Technology, College of Material Science and Technology, Taiyuan 030024, China"
            }
        ],
        "venue": "Materials Science and Engineering A-structural Materials Properties Microstructure and Processing",
        "year": 2016
    },
    "WynCZqFR": {
        "id": "WynCZqFR",
        "title": "Injectable and body temperature sensitive hydrogels based on chitosan and hyaluronic acid for pH sensitive drug release.",
        "abstract": "Hydrogels based on chitosan/hyaluronic acid/\u03b2-sodium glycerophosphate demonstrate injectability, body temperature sensitivity, pH sensitive drug release and adhesion to cancer cell. The drug (doxorubicin) loaded hydrogel precursor solutions are injectable and turn to hydrogels when the temperature is increased to body temperature. The acidic condition (pH 4.00) can trigger the release of drug and the cancer cell (Hela) can adhere to the surface of the hydrogels, which will be beneficial for tumor site-specific administration of drug. The mechanical strength, the gelation temperature, and the drug release behavior can be tuned by varying hyaluronic acid content. The mechanisms were characterized using dynamic mechanical analysis, Fourier transform infrared spectroscopy, scanning electron microscopy and fluorescence microscopy. The carboxyl group in hyaluronic acid can form the hydrogen bondings with the protonated amine in chitosan, which promotes the increase of mechanical strength of the hydrogels and depresses the initial burst release of drug from the hydrogel.",
        "keywords": [
            "Chitosan",
            "Drug delivery",
            "Hyaluronic acid",
            "Hydrogel",
            "Injectability"
        ],
        "authors": [
            {
                "name": "Wei Zhang",
                "org": "State Key Laboratory of Structure Analysis for Industrial Equipment, Department of Engineering Mechanics, Dalian University of Technology, Dalian 116024, China."
            },
            {
                "name": "Xin Jin",
                "org": "State Key Laboratory of Structure Analysis for Industrial Equipment, Department of Engineering Mechanics, Dalian University of Technology, Dalian 116024, China."
            },
            {
                "name": "Heng Li",
                "org": "State Key Laboratory of Structure Analysis for Industrial Equipment, Department of Engineering Mechanics, Dalian University of Technology, Dalian 116024, China."
            },
            {
                "name": "Run-Run Zhang",
                "org": "State Key Laboratory of Structure Analysis for Industrial Equipment, Department of Engineering Mechanics, Dalian University of Technology, Dalian 116024, China."
            },
            {
                "name": "Cheng-Wei Wu",
                "org": "State Key Laboratory of Structure Analysis for Industrial Equipment, Department of Engineering Mechanics, Dalian University of Technology, Dalian 116024, China. Electronic address: cwwu@dlut.edu.cn."
            }
        ],
        "venue": "Carbohydrate polymers",
        "year": 2018
    },
    "zuOxOs8p": {
        "id": "zuOxOs8p",
        "title": "Data on the experiments of temperature-sensitive hydrogels for pH-sensitive drug release and the characterizations of materials.",
        "abstract": "This article contains experimental data on the strain sweep, the calibration curve of drug (doxorubicin, DOX) and the characterizations of materials. Data included are related to the research article \"Injectable and body temperature sensitive hydrogels based on chitosan and hyaluronic acid for pH sensitive drug release\" (Zhang et al., 2017) [1]. The strain sweep experiments were performed on a rotational rheometer. The calibration curves were obtained by analyzing the absorbance of DOX solutions on a UV-vis-NIR spectrometer. Molecular weight ( ) of the hyaluronic acid (HA) and chitosan (CS) were determined by gel permeation chromatography (GPC). The deacetylation degree of CS was measured by acid base titration.",
        "keywords": "",
        "authors": [
            {
                "name": "Wei Zhang",
                "org": "State Key Laboratory of Structure Analysis for Industrial Equipment, Department of Engineering Mechanics, Dalian University of Technology, Dalian 116024, China."
            },
            {
                "name": "Xin Jin",
                "org": "State Key Laboratory of Structure Analysis for Industrial Equipment, Department of Engineering Mechanics, Dalian University of Technology, Dalian 116024, China."
            },
            {
                "name": "Heng Li",
                "org": "State Key Laboratory of Structure Analysis for Industrial Equipment, Department of Engineering Mechanics, Dalian University of Technology, Dalian 116024, China."
            },
            {
                "name": "Run-Run Zhang",
                "org": "State Key Laboratory of Structure Analysis for Industrial Equipment, Department of Engineering Mechanics, Dalian University of Technology, Dalian 116024, China."
            },
            {
                "name": "Cheng-Wei Wu",
                "org": "State Key Laboratory of Structure Analysis for Industrial Equipment, Department of Engineering Mechanics, Dalian University of Technology, Dalian 116024, China."
            }
        ],
        "venue": "Data in brief",
        "year": 2018
    },
    "OyhZ1MiB": {
        "id": "OyhZ1MiB",
        "title": "Clinical significance of detecting circulating tumor cells in colorectal cancer using subtraction enrichment and immunostaining-fluorescence in situ hybridization (SE-iFISH).",
        "abstract": "Circulating tumor cells (CTC) are useful in early detection of colorectal cancer. This study described a newly developed platform, integrated subtraction enrichment and immunostaining-fluorescence in situ hybridization (SE-iFISH), to assess CTCs in colorectal cancer. CTCs were detected by SE-iFISH in 40 of 44 preoperative colorectal cancer patients, and yielded a sensitivity of 90.9%, which was significantly higher than CellSearch system (90.9% vs. 43.2%, P=0.033). No significant association was found between tumor stage, survival and preoperative CTC number. CTCs were detected in 10 colorectal cancer patients one week after surgery; seven patients with decreased CTC numbers (compared with preoperative CTC number) were free of recurrence; whereas two of the three patients with increased CTC numbers had tumor recurrence. Moreover, CTCs were detected in 34 colorectal cancer patients three months after surgery; patients with CTC<2 at three months after surgery had significantly longer Progression Free Survival than those with CTC>=2 (P=0.019); patients with decreased CTC number (compared with preoperative CTC number) had significantly longer Progression Free Survival than those with increased CTC number (P=0.003). In conclusion, CTCs could be detected in various stages of colorectal cancer using SE-iFISH. Dynamic monitoring of CTC numbers could predict recurrence and prognosis.",
        "keywords": [
            "FISH",
            "biomarker",
            "circulating tumor cells",
            "colorectal cancer",
            "recurrence"
        ],
        "authors": [
            {
                "name": "Wei Wu",
                "org": "Department of General Surgery, The Aviation Hanzhong 3201 Hospital, Xi'an Jiao Tong University, Hanzhong 723000, Shaanxi, China."
            },
            {
                "name": "Zhenzhen Zhang",
                "org": "Zhangjiang Center for Translational Medicine, Shanghai 200120, China."
            },
            {
                "name": "Xian Hua Gao",
                "org": "Department of Colorectal Surgery, Changhai Hospital, The Second Military Medical University, Shanghai 200433, China."
            },
            {
                "name": "Zhen Shen",
                "org": "Department of General Surgery, The Aviation Hanzhong 3201 Hospital, Xi'an Jiao Tong University, Hanzhong 723000, Shaanxi, China."
            },
            {
                "name": "Yan Jing",
                "org": "Department of General Surgery, The Aviation Hanzhong 3201 Hospital, Xi'an Jiao Tong University, Hanzhong 723000, Shaanxi, China."
            },
            {
                "name": "Haibo Lu",
                "org": "Department of General Surgery, The Aviation Hanzhong 3201 Hospital, Xi'an Jiao Tong University, Hanzhong 723000, Shaanxi, China."
            },
            {
                "name": "Heng Li",
                "org": "Department of General Surgery, The Aviation Hanzhong 3201 Hospital, Xi'an Jiao Tong University, Hanzhong 723000, Shaanxi, China."
            },
            {
                "name": "Xiaoye Yang",
                "org": "Department of General Surgery, The Aviation Hanzhong 3201 Hospital, Xi'an Jiao Tong University, Hanzhong 723000, Shaanxi, China."
            },
            {
                "name": "Xiangbin Cui",
                "org": "Department of General Surgery, The Aviation Hanzhong 3201 Hospital, Xi'an Jiao Tong University, Hanzhong 723000, Shaanxi, China."
            },
            {
                "name": "Yuqing Li",
                "org": "Department of General Surgery, The Aviation Hanzhong 3201 Hospital, Xi'an Jiao Tong University, Hanzhong 723000, Shaanxi, China."
            },
            {
                "name": "Zheng Lou",
                "org": "Department of Colorectal Surgery, Changhai Hospital, The Second Military Medical University, Shanghai 200433, China."
            },
            {
                "name": "Peng Liu",
                "org": "Department of Colorectal Surgery, Changhai Hospital, The Second Military Medical University, Shanghai 200433, China."
            },
            {
                "name": "Cun Zhang",
                "org": "Department of General Surgery, The Aviation Hanzhong 3201 Hospital, Xi'an Jiao Tong University, Hanzhong 723000, Shaanxi, China."
            },
            {
                "name": "Wei Zhang",
                "org": "Department of Colorectal Surgery, Changhai Hospital, The Second Military Medical University, Shanghai 200433, China."
            }
        ],
        "venue": "Oncotarget",
        "year": 2017
    },
    "9o6XeuYi": {
        "id": "9o6XeuYi",
        "title": "Onion-structure bionic hydrogel capsules based on chitosan for regulating doxorubicin release.",
        "abstract": "Inspired by the multilayer structure of onion, herein, a novel strategy to prepare bionic multilayer hydrogel capsules for inhibiting burst release of doxorubicin (DOX) is reported. The bionic multilayer hydrogel capsules are prepared by the ionotropic crosslinking method. Compared with monolayer hydrogel capsules, the multilayer hydrogel capsules can largely homogenize the distribution of DOX and suppress the concentration gradient of DOX between the outermost hydrogel layer and external environment and the dense cuticular membranes of capsules can restrict the migration and diffusion of DOX. As a result, a significant inhibition of the burst release of DOX can be achieved. Moreover, the bionic multilayer hydrogel capsules demonstrate pH sensitivity and good biocompatibility to human epidermal keratinocyte (HaCaT) cells. This work opens up a new horizon in the burst release of biomaterial-based hydrogels for drug delivery system.",
        "keywords": [
            "Bionic multilayer",
            "Burst release",
            "Drug delivery",
            "Hydrogel capsules",
            "pH-sensitive"
        ],
        "authors": [
            {
                "name": "Wei Zhang",
                "org": "State Key Laboratory of Structure Analysis for Industrial Equipment, Department of Engineering Mechanics, Dalian University of Technology, Dalian 116024, China."
            },
            {
                "name": "Xin Jin",
                "org": "State Key Laboratory of Structure Analysis for Industrial Equipment, Department of Engineering Mechanics, Dalian University of Technology, Dalian 116024, China."
            },
            {
                "name": "Heng Li",
                "org": "State Key Laboratory of Structure Analysis for Industrial Equipment, Department of Engineering Mechanics, Dalian University of Technology, Dalian 116024, China."
            },
            {
                "name": "Cheng-Xiong Wei",
                "org": "State Key Laboratory of Structure Analysis for Industrial Equipment, Department of Engineering Mechanics, Dalian University of Technology, Dalian 116024, China."
            },
            {
                "name": "Cheng-Wei Wu",
                "org": "State Key Laboratory of Structure Analysis for Industrial Equipment, Department of Engineering Mechanics, Dalian University of Technology, Dalian 116024, China. Electronic address: cwwu@dlut.edu.cn."
            }
        ],
        "venue": "Carbohydrate polymers",
        "year": 2019
    },
    "Y4qemKSc": {
        "id": "Y4qemKSc",
        "title": "Magnetic nanoparticles with low Curie temperature and high heating efficiency for self-regulating temperature hyperthermia",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Wei Zhang",
                "org": ""
            },
            {
                "name": "Xiaogang Yu",
                "org": ""
            },
            {
                "name": "Heng Li",
                "org": ""
            },
            {
                "name": "Dili Dong",
                "org": ""
            },
            {
                "name": "Xudong Zuo",
                "org": ""
            },
            {
                "name": "Cheng-wei Wu",
                "org": ""
            }
        ],
        "venue": "Journal of Magnetism and Magnetic Materials",
        "year": 2019
    },
    "H4dJotlm": {
        "id": "H4dJotlm",
        "title": "Auditory brainstem responses after electrolytic lesions in bilateral subdivisions of the medial geniculate body of tree shrews.",
        "abstract": "This study aimed to establish a tree shrew model of bilateral electrolytic lesions in the medial geniculate body (MGB) to determine the advantages of using a tree shrew model and to assess the pattern of sound processing in tree shrews after bilateral electrolytic damage in different parts of the MGB. The auditory brainstem responses (ABRs) of a normal control group (n\u00a0=\u00a030) and an electrical damage group (n\u00a0=\u00a030) were tested at 0\u00a0h, 24\u00a0h, 48\u00a0h, 72\u00a0h, 7\u00a0days, 15\u00a0days, and 30\u00a0days after surgery. (1) The bilateral ablations group exhibited a significant increase in the ABR threshold of the electrolytic damage group between pre- and post-operation. (2) There were significant increases in the I-VI latencies at 0\u00a0h after MGBd and MGBm lesions and at 24\u00a0h after MGBv lesion. (3) The amplitudes of wave VI were significantly decreased at 24\u00a0h and 48\u00a0h after MGBd lesion, at 72\u00a0h and 7\u00a0days after MGBm lesion, and at 24\u00a0h, 48\u00a0h, 72\u00a0h, and 7\u00a0days after MGBv lesion. (1) The electrolytic damage group suffered hearing loss that did not recover and appeared to be difficult to fully repair after bilateral ablation. (2) The latencies and amplitudes of responses in the MGB following bilateral electrolytic lesion were restored to pre-operation levels after 15-30\u00a0days, suggesting that a portion of the central nuclei lesion was reversible. (3) The tree shrew auditory animal model has many advantages compared to other animal models, such as greater complexity of brain structure and auditory nuclei fiber connections, which make the results of this experiment more useful for clinical diagnoses compared with studies using rats and guinea pigs.",
        "keywords": [
            "Auditory brainstem responses",
            "Electrolytic lesion",
            "Medial geniculate body",
            "Tree shrew"
        ],
        "authors": [
            {
                "name": "Meichan Zhu",
                "org": "Department of Otorhinolaryngology and Head and Neck Surgery, First Affiliated Hospital of Guangxi Medical University, No.6 Shuangyong Road, Nanning, Guangxi, 530021, China."
            },
            {
                "name": "Heng Li",
                "org": "Department of Otorhinolaryngology and Head and Neck Surgery, First Affiliated Hospital of Guangxi Medical University, No.6 Shuangyong Road, Nanning, Guangxi, 530021, China."
            },
            {
                "name": "Bibek Gyanwali",
                "org": "Department of Otorhinolaryngology and Head and Neck Surgery, First Affiliated Hospital of Guangxi Medical University, No.6 Shuangyong Road, Nanning, Guangxi, 530021, China."
            },
            {
                "name": "Guangyao He",
                "org": "Department of Otorhinolaryngology and Head and Neck Surgery, First Affiliated Hospital of Guangxi Medical University, No.6 Shuangyong Road, Nanning, Guangxi, 530021, China."
            },
            {
                "name": "Chenglin Qi",
                "org": "Department of Otorhinolaryngology and Head and Neck Surgery, First Affiliated Hospital of Guangxi Medical University, No.6 Shuangyong Road, Nanning, Guangxi, 530021, China."
            },
            {
                "name": "Xuemin Yang",
                "org": "Department of Otorhinolaryngology and Head and Neck Surgery, First Affiliated Hospital of Guangxi Medical University, No.6 Shuangyong Road, Nanning, Guangxi, 530021, China."
            },
            {
                "name": "Zhenhua Li",
                "org": "Department of Otorhinolaryngology and Head and Neck Surgery, First Affiliated Hospital of Guangxi Medical University, No.6 Shuangyong Road, Nanning, Guangxi, 530021, China."
            },
            {
                "name": "Zhenxing Yao",
                "org": "Department of Otorhinolaryngology and Head and Neck Surgery, First Affiliated Hospital of Guangxi Medical University, No.6 Shuangyong Road, Nanning, Guangxi, 530021, China."
            },
            {
                "name": "Zhi Wang",
                "org": "Department of Otorhinolaryngology and Head and Neck Surgery, First Affiliated Hospital of Guangxi Medical University, No.6 Shuangyong Road, Nanning, Guangxi, 530021, China."
            },
            {
                "name": "Anzhou Tang",
                "org": "Department of Otorhinolaryngology and Head and Neck Surgery, First Affiliated Hospital of Guangxi Medical University, No.6 Shuangyong Road, Nanning, Guangxi, 530021, China. anzhoutang321@163.com."
            }
        ],
        "venue": "Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology",
        "year": 2017
    },
    "x5694cGo": {
        "id": "x5694cGo",
        "title": "Micro-CT study of the human cochlear aqueduct.",
        "abstract": "Micro-CT adequately displayed the bony CA canal and provided a new method for anatomical studies of the CA and a basis for functional studies.",
        "keywords": [
            "Micro-CT",
            "Cochlear aqueduct",
            "Inferior cochlear vein",
            "High-resolution CT"
        ],
        "authors": [
            {
                "name": "Zhenghua Li",
                "org": "Otorhinolaryngology Head and Neck Surgery, Liuyang traditional Chinese Medicine hospital, Liuyang, Hunan, China."
            },
            {
                "name": "Dazhi Shi",
                "org": "Otorhinolaryngology Head and Neck Surgery, The Second Affiliated Hospital of University of South China, Hengyang, Hunan, China."
            },
            {
                "name": "Heng Li",
                "org": "Otorhinolaryngology Head and Neck Surgery, Frist Affiliated Hospital Of Guangxi Medical University, Nanning, Guangxi, China."
            },
            {
                "name": "Songhua Tan",
                "org": "Otorhinolaryngology Head and Neck Surgery, Frist Affiliated Hospital Of Guangxi Medical University, Nanning, Guangxi, China."
            },
            {
                "name": "Yikang Liu",
                "org": "Otorhinolaryngology Head and Neck Surgery, Frist Affiliated Hospital Of Guangxi Medical University, Nanning, Guangxi, China."
            },
            {
                "name": "Chenglin Qi",
                "org": "Otorhinolaryngology Head and Neck Surgery, Frist Affiliated Hospital Of Guangxi Medical University, Nanning, Guangxi, China."
            },
            {
                "name": "Anzhou Tang",
                "org": "Department of Otolaryngology Head and Neck Surgery, First Affiliated Hospital of Guangxi Medical University, No. 6 Shuangyong Road, Nanning, 530021, Guangxi, China. anzhoutang@163.com."
            }
        ],
        "venue": "Surgical and radiologic anatomy : SRA",
        "year": 2018
    },
    "DlmQ3vGg": {
        "id": "DlmQ3vGg",
        "title": "The effects of the auditory brainstem response before and after fluoro-gold injection in medial geniculate body.",
        "abstract": "The FG retrograde tracing technique accurately displays the anatomical location of the auditory pathway in the tree shrew. The change in ABR waves suggested that there was a functional abnormality in the central auditory pathway after FG injection. The auditory thalamus may have self-regulating properties.",
        "keywords": "",
        "authors": [
            {
                "name": "Meichan Zhu",
                "org": "Department of Otorhinolaryngology and Head and Neck Surgery, First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China."
            },
            {
                "name": "Guangyao He",
                "org": "Department of Otorhinolaryngology and Head and Neck Surgery, First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China."
            },
            {
                "name": "Heng Li",
                "org": "Department of Otorhinolaryngology and Head and Neck Surgery, First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China."
            },
            {
                "name": "Mao Xie",
                "org": "Department of Otorhinolaryngology and Head and Neck Surgery, First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China."
            },
            {
                "name": "Bibek Gyanwali",
                "org": "Department of Otorhinolaryngology and Head and Neck Surgery, First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China."
            },
            {
                "name": "Lihong Xie",
                "org": "Department of Otorhinolaryngology and Head and Neck Surgery, First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China."
            },
            {
                "name": "Yikang Liu",
                "org": "Department of Otorhinolaryngology and Head and Neck Surgery, First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China."
            },
            {
                "name": "Songhua Tan",
                "org": "Department of Otorhinolaryngology and Head and Neck Surgery, First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China."
            },
            {
                "name": "Tiansong Lin",
                "org": "Department of Otorhinolaryngology and Head and Neck Surgery, First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China."
            },
            {
                "name": "Anzhou Tang",
                "org": "Department of Otorhinolaryngology and Head and Neck Surgery, First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China."
            }
        ],
        "venue": "Neuro endocrinology letters",
        "year": 2015
    },
    "wA5TNx6M": {
        "id": "wA5TNx6M",
        "title": "The characterization of auditory brainstem response (ABR) waveforms: A study in tree shrews (Tupaia belangeri).",
        "abstract": "To characterize the patterns of ABR waves in tree shrews, we must understand the hearing sensitivity and auditory function of healthy adult tree shrews. Fifteen tree shrews (30 ears) were stimulated with clicks and tone-pips at 11 different frequencies from 1 to 60\u202fkHz. The ABR waves were recorded and analyzed. The ABR consisted of five to seven positive waves in the first 10\u202fms after a click stimulus, and the average hearing threshold of component III was 27.86\u202f\u00b1\u202f3.78\u202fdB SPL. Wave III was the largest and most clear. The ABR threshold was related to the tone-pip sitmulus by a \"U\" shaped curve. The sensitive frequency was approximately 8\u202fkHz in tree shrews. The latencies systematically decreased with increasing stimulus frequencies. The ABR amplitudes of wave III increased as the sound pressure level increased. All of these results provide an empirical basis for future studies of hearing diseases in tree shrews.",
        "keywords": [
            "Auditory brainstem response",
            "Ear",
            "Primates",
            "Tree shrew (Tupaia belangeri)"
        ],
        "authors": [
            {
                "name": "Lihong Xie",
                "org": "Department of Otorhinolaryngology and Head and Neck Surgery, First Affiliated Hospital of Guangxi Medical University, 530021 Nanning, Guangxi, China."
            },
            {
                "name": "Menglin Wang",
                "org": "Department of Otorhinolaryngology and Head and Neck Surgery, First Affiliated Hospital of Guangxi Medical University, 530021 Nanning, Guangxi, China."
            },
            {
                "name": "Ting Liao",
                "org": "Department of Otorhinolaryngology and Head and Neck Surgery, First Affiliated Hospital of Guangxi Medical University, 530021 Nanning, Guangxi, China."
            },
            {
                "name": "Songhua Tan",
                "org": "Department of Otorhinolaryngology and Head and Neck Surgery, First Affiliated Hospital of Guangxi Medical University, 530021 Nanning, Guangxi, China."
            },
            {
                "name": "Kai Sun",
                "org": "Department of Otorhinolaryngology and Head and Neck Surgery, First Affiliated Hospital of Guangxi Medical University, 530021 Nanning, Guangxi, China."
            },
            {
                "name": "Heng Li",
                "org": "Department of Otorhinolaryngology and Head and Neck Surgery, First Affiliated Hospital of Guangxi Medical University, 530021 Nanning, Guangxi, China."
            },
            {
                "name": "Qin Fang",
                "org": "Department of Otorhinolaryngology and Head and Neck Surgery, First Affiliated Hospital of Guangxi Medical University, 530021 Nanning, Guangxi, China."
            },
            {
                "name": "Anzhou Tang",
                "org": "Department of Otorhinolaryngology and Head and Neck Surgery, First Affiliated Hospital of Guangxi Medical University, 530021 Nanning, Guangxi, China."
            }
        ],
        "venue": "Journal of otology",
        "year": 2018
    },
    "qbeC7eDP": {
        "id": "qbeC7eDP",
        "title": "Anatomical Variations of the Human Cochlea Determined from Micro-CT and High-Resolution CT Imaging and Reconstruction: ANATOMICAL VARIATIONS OF THE HUMAN COCHLEA",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Jie Tang",
                "org": "Department of Otolaryngology Head and Neck SurgeryFirst Affiliated Hospital of Guangxi Medical UniversityGuangxi Nanning 530000 People's Republic of China"
            },
            {
                "name": "Xianglong Tang",
                "org": "Department of Otolaryngology Head and Neck SurgeryFirst Affiliated Hospital of Guangxi Medical UniversityGuangxi Nanning 530000 People's Republic of China"
            },
            {
                "name": "Zhenhua Li",
                "org": "Department of Otolaryngology Head and Neck SurgeryFirst Affiliated Hospital of Guangxi Medical UniversityGuangxi Nanning 530000 People's Republic of China"
            },
            {
                "name": "Yikang Liu",
                "org": "Department of Otolaryngology Head and Neck SurgeryFirst Affiliated Hospital of Guangxi Medical UniversityGuangxi Nanning 530000 People's Republic of China"
            },
            {
                "name": "SongHua Tan",
                "org": "Department of Otolaryngology Head and Neck SurgeryFirst Affiliated Hospital of Guangxi Medical UniversityGuangxi Nanning 530000 People's Republic of China"
            },
            {
                "name": "Heng Li",
                "org": "Department of Otolaryngology Head and Neck SurgeryFirst Affiliated Hospital of Guangxi Medical UniversityGuangxi Nanning 530000 People's Republic of China"
            },
            {
                "name": "RongDan Ke",
                "org": "Department of Otolaryngology Head and Neck SurgeryFirst Affiliated Hospital of Guangxi Medical UniversityGuangxi Nanning 530000 People's Republic of China"
            },
            {
                "name": "Zhi Wang",
                "org": "Department of Otolaryngology Head and Neck SurgeryFirst Affiliated Hospital of Guangxi Medical UniversityGuangxi Nanning 530000 People's Republic of China"
            },
            {
                "name": "Li Gong",
                "org": "Department of Otolaryngology Head and Neck SurgeryFirst Affiliated Hospital of Guangxi Medical UniversityGuangxi Nanning 530000 People's Republic of China"
            },
            {
                "name": "Anzhou Tang",
                "org": "Department of Otolaryngology Head and Neck SurgeryFirst Affiliated Hospital of Guangxi Medical UniversityGuangxi Nanning 530000 People's Republic of China"
            }
        ],
        "venue": "Anatomical Record-advances in Integrative Anatomy and Evolutionary Biology",
        "year": 2018
    },
    "55bTbrXt": {
        "id": "55bTbrXt",
        "title": "Antimicrobial mechanism of theaflavins: They target 1-deoxy-D-xylulose 5-phosphate reductoisomerase, the key enzyme of the MEP terpenoid biosynthetic pathway",
        "abstract": "A Nature Research Journal",
        "keywords": "",
        "authors": [
            {
                "name": "Xian Hui",
                "org": "Key Laboratory of Resource Biology and Biotechnology in Western China (Ministry of Education), College of Life Sciences, Northwest University, 229 North Taibai Road, Xi\u2019an, Shaanxi 710069, China"
            },
            {
                "name": "Qiao Yue",
                "org": "Key Laboratory of Resource Biology and Biotechnology in Western China (Ministry of Education), College of Life Sciences, Northwest University, 229 North Taibai Road, Xi\u2019an, Shaanxi 710069, China"
            },
            {
                "name": "Dan-Dan Zhang",
                "org": "Key Laboratory of Resource Biology and Biotechnology in Western China (Ministry of Education), College of Life Sciences, Northwest University, 229 North Taibai Road, Xi\u2019an, Shaanxi 710069, China"
            },
            {
                "name": "Heng Li",
                "org": "Key Laboratory of Resource Biology and Biotechnology in Western China (Ministry of Education), College of Life Sciences, Northwest University, 229 North Taibai Road, Xi\u2019an, Shaanxi 710069, China"
            },
            {
                "name": "Shao-Qing Yang",
                "org": "Key Laboratory of Resource Biology and Biotechnology in Western China (Ministry of Education), College of Life Sciences, Northwest University, 229 North Taibai Road, Xi\u2019an, Shaanxi 710069, China"
            },
            {
                "name": "Wen-Yun Gao",
                "org": "Key Laboratory of Resource Biology and Biotechnology in Western China (Ministry of Education), College of Life Sciences, Northwest University, 229 North Taibai Road, Xi\u2019an, Shaanxi 710069, China"
            }
        ],
        "venue": "Scientific Reports",
        "year": 2016
    },
    "pBukDEOo": {
        "id": "pBukDEOo",
        "title": "Geniposide and Gentiopicroside Suppress Hepatic Gluconeogenesis via Regulation of AKT-FOXO1 Pathway.",
        "abstract": "Geniposide and gentiopicroside might reduce blood glucose and suppress hepatic gluconeogenesis by regulating the AKT-FOXO1 pathway, and the potential use of these two iridoid glucosides as anti-diabetic agents merits further in-depth exploration.",
        "keywords": [
            "AKT",
            "FOXO1",
            "Geniposide",
            "Gentiopicroside",
            "Hepatic gluconeogenesis"
        ],
        "authors": [
            {
                "name": "Shao-Qing Yang",
                "org": "College of Life Sciences, Northwest University, 229 North Taibai Road, Xi'an, Shaanxi, China."
            },
            {
                "name": "Ye-Dan Chen",
                "org": "College of Life Sciences, Northwest University, 229 North Taibai Road, Xi'an, Shaanxi, China."
            },
            {
                "name": "Heng Li",
                "org": "College of Life Sciences, Northwest University, 229 North Taibai Road, Xi'an, Shaanxi, China."
            },
            {
                "name": "Xian Hui",
                "org": "College of Life Sciences, Northwest University, 229 North Taibai Road, Xi'an, Shaanxi, China."
            },
            {
                "name": "Wen-Yun Gao",
                "org": "College of Life Sciences, Northwest University, 229 North Taibai Road, Xi'an, Shaanxi, China. Electronic address: gaowenyun@nwu.edu.cn."
            }
        ],
        "venue": "Archives of medical research",
        "year": 2018
    },
    "PHlUu8Ou": {
        "id": "PHlUu8Ou",
        "title": "Inhibition of green tea and the catechins against 1-deoxy-d-xylulose 5-phosphate reductoisomerase, the key enzyme of the MEP terpenoid biosynthetic pathway.",
        "abstract": "1-Deoxy-d-xylulose 5-phosphate reductoisomerase (DXR) is the first committed enzyme in the MEP terpenoid biosynthetic pathway and also a validated antimicrobial target. Green tea which is rich in polyphenolic components such as the catechins, possesses a plenty of pharmacological activities, in particular an antibacterial effect. To uncover the antibacterial mechanism of green tea and to seek new DXR inhibitors from natural sources, the DXR inhibitory activity of green tea and its main antimicrobial catechins were investigated in this study. The results show that the raw extract of green tea and its ethyl acetate fraction are able to suppress DXR activity explicitly. Further determination of the DXR inhibitory capacity of eight catechin compounds demonstrates that the most active compound is gallocatechin gallate that is able to inhibit around 50% activity of DXR at 25\u03bcM. Based on these data, the primary structure-activity relationship of the catechins against DXR is discussed. This study would be very helpful to elucidate the antimicrobial mechanism of green tea and the catechins and also would be very useful to direct the rational utilization of them as food additives. ",
        "keywords": [
            "1-deoxy-d-xylulose 5-phosphate reductoisomerase",
            "Catechins",
            "Epigallocatechin gallate (PubChem CID: 65064)",
            "Gallocatechin gallate (PubChem CID: 5276890)",
            "Green tea",
            "Inhibition",
            "MEP pathway"
        ],
        "authors": [
            {
                "name": "Xian Hui",
                "org": "Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, 229 North Taibai Road, Xi'an, Shaanxi 710069, China."
            },
            {
                "name": "Hui Liu",
                "org": "Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, 229 North Taibai Road, Xi'an, Shaanxi 710069, China."
            },
            {
                "name": "Fang-Lin Tian",
                "org": "Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, 229 North Taibai Road, Xi'an, Shaanxi 710069, China."
            },
            {
                "name": "Fei-Fei Li",
                "org": "Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, 229 North Taibai Road, Xi'an, Shaanxi 710069, China."
            },
            {
                "name": "Heng Li",
                "org": "Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, 229 North Taibai Road, Xi'an, Shaanxi 710069, China."
            },
            {
                "name": "Wen-Yun Gao",
                "org": "Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, 229 North Taibai Road, Xi'an, Shaanxi 710069, China. Electronic address: gaowenyun@nwu.edu.cn."
            }
        ],
        "venue": "Fitoterapia",
        "year": 2016
    },
    "X3Y0AYBw": {
        "id": "X3Y0AYBw",
        "title": "Determination of Diacetyl in Beer by a Precolumn Derivatization-HPLC-UV Method Using 4-(2,3-Dimethyl-6-quinoxalinyl)-1,2-benzenediamine as a Derivatizing Reagent.",
        "abstract": "Diacetyl is an important flavoring compound in many foods, especially in beer. In the present study, we developed and validated a new precolumn derivatization HPLC-UV method for the determination of diacetyl using 4-(2,3-dimethyl-6-quinoxalinyl)-1,2-benzenediamine as a novel derivatizing reagent. After derivatization with the reagent at a pH value 4.0 at ambient temperature for 10 min, diacetyl was analyzed on an ODS column and detected at 254 nm. The results show that the correlation coefficient of the method is 0.9991 in the range of 0.10 to 100.0 \u03bcM diacetyl, and the limit of detection is 0.02 \u03bcM. The method was further evaluated in the analysis of beer samples with the recoveries ranging from 94.4 to 102.6% and RSDs from 1.36 to 3.33%. The concentrations of diacetyl in 8 beer samples were determined in the range of 0.19 to 0.42 \u03bcM. The method established in this study may be well suitable for the determination of diacetyl in beer.",
        "keywords": [
            "4-(2",
            "3-dimethyl-6-quinoxalinyl)-1",
            "2-benzenediamine",
            "HPLC",
            "diacetyl determination",
            "precolumn derivatization"
        ],
        "authors": [
            {
                "name": "Ji-Yu Wang",
                "org": "National Engineering Research Center for Miniaturized Detection Systems and College of Life Sciences, Northwest University , 229 North Taibai Road, Xi'an, Shaanxi 710069, China."
            },
            {
                "name": "Xin-Jie Wang",
                "org": "National Engineering Research Center for Miniaturized Detection Systems and College of Life Sciences, Northwest University , 229 North Taibai Road, Xi'an, Shaanxi 710069, China."
            },
            {
                "name": "Xian Hui",
                "org": "National Engineering Research Center for Miniaturized Detection Systems and College of Life Sciences, Northwest University , 229 North Taibai Road, Xi'an, Shaanxi 710069, China."
            },
            {
                "name": "Shui-Hong Hua",
                "org": "National Engineering Research Center for Miniaturized Detection Systems and College of Life Sciences, Northwest University , 229 North Taibai Road, Xi'an, Shaanxi 710069, China."
            },
            {
                "name": "Heng Li",
                "org": "National Engineering Research Center for Miniaturized Detection Systems and College of Life Sciences, Northwest University , 229 North Taibai Road, Xi'an, Shaanxi 710069, China."
            },
            {
                "name": "Wen-Yun Gao",
                "org": "National Engineering Research Center for Miniaturized Detection Systems and College of Life Sciences, Northwest University , 229 North Taibai Road, Xi'an, Shaanxi 710069, China."
            }
        ],
        "venue": "Journal of agricultural and food chemistry",
        "year": 2017
    },
    "cXBXYa63": {
        "id": "cXBXYa63",
        "title": "Elevated levels of \u03b1-dicarbonyl compounds in the plasma of type II diabetics and their relevance with diabetic nephropathy.",
        "abstract": "The presence of \u03b1\u2011dicarbonyl compounds (\u03b1-DCs) in vivo has been associated with the development of complications of diabetes mellitus (DM) and also with other chronic diseases. Therefore, quantitative analysis of \u03b1-DCs in body fluids is crucial to understand their roles in the formation of these chronic diseases. We established in this study a practical HPLC-UV method to measure 3\u2011deoxyglucosone (3-DG), glyoxal (GO), methylglyoxal (MGO), diacetyl (DA), and pentane\u20112,3\u2011dione (PD) in blood plasma using 4\u2011(2,3\u2011dimethyl\u20116\u2011quinoxalinyl)\u20111,2\u2011benzenediamine (DQB) as a derivatizing reagent. The derivatizing reaction could be carried out quickly under mild conditions and the HPLC determination is simple, sensitive, and easy to operate. The recoveries of the \u03b1-DCs are between 85.26% and 110.20% (intra-day) and 87.25% and 103.18% (inter-day); the RSDs are between 1.28% and 5.69% (intra-day) and 2.26% and 6.34% (inter-day). We found the plasma levels of 3-DG, GO, and MGO in the diabetic patients are all significantly higher than those in healthy subjects. The results also show that the contents of GO and MGO in diabetic nephropathy (DN) patients are both significantly higher than those in simple T2DM patients. Moreover, it is found for the first time that the plasma level of GO might be a potential predictor of DN. The developed method would be useful for the measurements of the plasma \u03b1-DCs and the data acquired could be informative in the diagnosis of DM complications.",
        "keywords": [
            "Blood plasma",
            "Diabetic nephropathy",
            "Type 2 diabetes mellitus",
            "\u03b1-Dicarbonyl compounds"
        ],
        "authors": [
            {
                "name": "Xin-Jie Wang",
                "org": "National Engineering Research Center for Miniaturized Detection Systems and College of Life Sciences, Northwest University, 229 North Taibai Road, Xi'an, Shaanxi 710069, China."
            },
            {
                "name": "Sheng-Bo Ma",
                "org": "National Engineering Research Center for Miniaturized Detection Systems and College of Life Sciences, Northwest University, 229 North Taibai Road, Xi'an, Shaanxi 710069, China."
            },
            {
                "name": "Zhuo-Feng Liu",
                "org": "Friendship Hospital of Shaanxi Province, 227 West Youyi Road, Xi'an, Shaanxi 710000, China."
            },
            {
                "name": "Heng Li",
                "org": "National Engineering Research Center for Miniaturized Detection Systems and College of Life Sciences, Northwest University, 229 North Taibai Road, Xi'an, Shaanxi 710069, China."
            },
            {
                "name": "Wen-Yun Gao",
                "org": "National Engineering Research Center for Miniaturized Detection Systems and College of Life Sciences, Northwest University, 229 North Taibai Road, Xi'an, Shaanxi 710069, China. Electronic address: gaowenyun@nwu.edu.cn."
            }
        ],
        "venue": "Journal of chromatography. B, Analytical technologies in the biomedical and life sciences",
        "year": 2018
    },
    "AzIB7Ph4": {
        "id": "AzIB7Ph4",
        "title": "Antimicrobial mechanism of epigallocatechin gallate and gallocatechin gallate: They target 1-deoxy-d-xylulose 5-phosphate reductoisomerase, the key enzyme of the MEP terpenoid biosynthetic pathway",
        "abstract": "Abstract   The catechins EGCG and GCG show a variety of pharmacological activities, especially an antibacterial capacity, but their modes of antimicrobial action have not been fully elucidated. 1-Deoxy- d -xylulose 5-phosphate reductoisomerase (DXR), the first key enzyme in the MEP pathway for terpenoid biosynthesis, is a recently validated antimicrobial target. In order to disclose the antibacterial mechanism of EGCG and GCG, the DXR inhibitory activity of them was investigated in this study. The data show that EGCG and GCG both could specifically suppress the activity of DXR, with EGCG exhibiting relatively low effect against DXR (IC 50  about 210\u00a0\u03bcM) and GCG displaying strong activity (IC 50  27.5\u00a0\u03bcM). In addition, studies on inhibition kinetics of the catechins against DXR demonstrate that they are competitive inhibitors of DXR against DXP and uncompetitive inhibitors with respect to NADPH. Meanwhile, the possible interactions between DXR and the catechine, esyth onlols were simulated via docking experiments.",
        "keywords": "",
        "authors": [
            {
                "name": "Xian Hui",
                "org": "National Engineering Research Center for Miniaturised Detection Systems and College of Life Sciences, Northwest University, 229 North Taibai Road, Xi'an, Shaanxi 710069, China"
            },
            {
                "name": "Shui-Hong Hua",
                "org": "National Engineering Research Center for Miniaturised Detection Systems and College of Life Sciences, Northwest University, 229 North Taibai Road, Xi'an, Shaanxi 710069, China"
            },
            {
                "name": "Qian-Qian Wu",
                "org": "National Engineering Research Center for Miniaturised Detection Systems and College of Life Sciences, Northwest University, 229 North Taibai Road, Xi'an, Shaanxi 710069, China"
            },
            {
                "name": "Heng Li",
                "org": "National Engineering Research Center for Miniaturised Detection Systems and College of Life Sciences, Northwest University, 229 North Taibai Road, Xi'an, Shaanxi 710069, China"
            },
            {
                "name": "Wen-Yun Gao",
                "org": "National Engineering Research Center for Miniaturised Detection Systems and College of Life Sciences, Northwest University, 229 North Taibai Road, Xi'an, Shaanxi 710069, China"
            }
        ],
        "venue": "Archives of Biochemistry and Biophysics",
        "year": 2017
    },
    "kWe0u2Ih": {
        "id": "kWe0u2Ih",
        "title": "An improved enzymatic method for the preparation of (R)-phenylacetyl carbinol",
        "abstract": "(R)-Phenylacetyl carbinol (R-PAC) is one of the key chiral \u03b1-hydroxyketones utilized as a synthon in the synthesis of a number of pharmaceuticals having \u03b1- and \u03b2-adrenergic properties. An improved procedure for the preparation of the compound using the glutathione S-transferase-tag fused catalytic subunit of Escherichia coli acetohydroxyacid synthase I as a catalyst was established in this study. The results showed that under the optimized conditions the target molecule was able to be obtained with an isolated yield of 80.6% and an ee value of higher than 98%. This method could not only ease the preparation of R-PAC, but promote the synthetic applications of E. coli AHAS I as well.",
        "keywords": "",
        "authors": [
            {
                "name": "Heng Li",
                "org": "National Engineering Research Center for Miniaturized Detection Systems, College of Life Sciences, Northwest University,Xi'an,China"
            },
            {
                "name": "Nan Liu",
                "org": "Department of Experimental Surgery, Tangdu Hospital, Fourth Military Medical University,Xi'an,China"
            },
            {
                "name": "Xian Hui",
                "org": "National Engineering Research Center for Miniaturized Detection Systems, College of Life Sciences, Northwest University,Xi'an,China"
            },
            {
                "name": "Wen-Yun Gao",
                "org": "National Engineering Research Center for Miniaturized Detection Systems, College of Life Sciences, Northwest University,Xi'an,China"
            }
        ],
        "venue": "RSC Advances",
        "year": 2017
    },
    "NkYOCVqa": {
        "id": "NkYOCVqa",
        "title": "Antimicrobial mechanism of the major active essential oil compounds and their structure\u2013activity relationship",
        "abstract": "Plant essential oils possess many sorts of bioactivities including microbicidal property. A number of essential oil components have been characterized as effective antibacterial agents. In this study, we selected several major antibacterial essential oil compounds and investigated their inhibition against 1-deoxy-D-xylulose 5-phosphate reductoisomerase, the key enzyme of the 2-methyl-D-erythritol 4-phosphate terpenoid biosynthetic pathway and also a validated target for screening novel antibiotics. The results show that compounds eugenol and carvacrol display medium to weak inhibition against 1-deoxy-D-xylulose 5-phosphate reductoisomerase with IC50 values being about 97.3 and 139.2 \u03bcM, repectively; Compounds thymol, geraniol, linalool, and nerol exhibit weak 1-deoxy-D-xylulose 5-phosphate reductoisomerase inhibitory activity while perillaldehyde, cinnamaldehyde, \u03b1-terpineol, and citral possess undetectable inhibition against1-deoxy-D-xylulose 5-phosphate reductoisomerase. Based on these data, the structure\u2013activity relationship of these compounds is discussed. Additionally, the inhibition kinetics of carvacrol and eugenol are also determinated. These results can not only deepen our understanding toward the antimicrobial mechanisms of eugenol and carvacrol, but also direct the reasonable application of these antimicrobial agents in medical pathology and in the control of plant diseases as well as in food industry.",
        "keywords": "",
        "authors": [
            {
                "name": "Xian Hui",
                "org": "Northwest University"
            },
            {
                "name": "Ge Yan",
                "org": "Northwest University"
            },
            {
                "name": "Fang-Lin Tian",
                "org": "Northwest University"
            },
            {
                "name": "Heng Li",
                "org": "Northwest University"
            },
            {
                "name": "Wen-Yun Gao",
                "org": "Northwest University"
            }
        ],
        "venue": "Medicinal Chemistry Research",
        "year": 2017
    },
    "zmH9uUSc": {
        "id": "zmH9uUSc",
        "title": "Quantitative analyses of \u03b1-dicarbonyl compounds in food samples by HPLC using 4-(2,3-dimethyl-6-quinoxalinyl)-1,2-benzenediamine as a derivatizing reagent",
        "abstract": "Abstract   \u03b1-Dicarbonyl compounds, such as 3-deoxyglucosone (3-DG), glyoxal (Gly), methylglyoxal (MGly), diacetyl (DA), and pentane-2,3-dione (PD) have been widely studied because they are the main precursors of advanced glycation end products. In this work, an analytical procedure was developed for the determination of these compounds by HPLC-UV using 4-(2,3-dimethyl-6-quinoxalinyl)-1,2-benzenediamine (DQB) as a novel derivatizing reagent. After derivatization at pH\u202f9.0 and ambient temperature for 30\u202fmin, these five compounds were analyzed by HPLC. The results showed that the linear correlation coefficients (R 2 ) of the method for the five analytes are between 0.994 and 0.999 in broad concentration ranges, the limits of detection are 0.050\u202f\u03bcM (3-DG), 0.050\u202f\u03bcM (Gly), 0.050\u202f\u03bcM (MGly), 0.020\u202f\u03bcM (DA), and 0.025\u202f\u03bcM (PD), respectively. The method was further evaluated in the analyses of many kinds of food samples employing the standard addition method with the RSDs ranging from 0.43 to 4.07% and the recoveries from 85% to 103%.",
        "keywords": "",
        "authors": [
            {
                "name": "Xin-Jie Wang",
                "org": "National Engineering Research Center for Miniaturized Detection Systems and College of Life Sciences, Northwest University, 229 North Taibai Road, Xi'an, Shaanxi 710069, China"
            },
            {
                "name": "Feng Gao",
                "org": "National Engineering Research Center for Miniaturized Detection Systems and College of Life Sciences, Northwest University, 229 North Taibai Road, Xi'an, Shaanxi 710069, China"
            },
            {
                "name": "Lu-Chao Li",
                "org": "National Engineering Research Center for Miniaturized Detection Systems and College of Life Sciences, Northwest University, 229 North Taibai Road, Xi'an, Shaanxi 710069, China"
            },
            {
                "name": "Xian Hui",
                "org": "National Engineering Research Center for Miniaturized Detection Systems and College of Life Sciences, Northwest University, 229 North Taibai Road, Xi'an, Shaanxi 710069, China"
            },
            {
                "name": "Heng Li",
                "org": "National Engineering Research Center for Miniaturized Detection Systems and College of Life Sciences, Northwest University, 229 North Taibai Road, Xi'an, Shaanxi 710069, China"
            },
            {
                "name": "Wen-Yun Gao",
                "org": "National Engineering Research Center for Miniaturized Detection Systems and College of Life Sciences, Northwest University, 229 North Taibai Road, Xi'an, Shaanxi 710069, China"
            }
        ],
        "venue": "Microchemical Journal",
        "year": 2018
    },
    "9sRZb4ob": {
        "authors": [
            {
                "name": "Hua Peng",
                "org": "Key Lab of Bio-Resources and Eco-Environment, Ministry of Education, College of Life Science"
            },
            {
                "name": "Jun Chun",
                "org": "Key Lab of Bio-Resources and Eco-Environment, Ministry of Education, College of Life Science"
            },
            {
                "name": "Tao-bo Ai",
                "org": "Key Lab of Bio-Resources and Eco-Environment, Ministry of Education, College of Life Science"
            },
            {
                "name": "Yong-ao Tong",
                "org": "Key Lab of Bio-Resources and Eco-Environment, Ministry of Education, College of Life Science"
            },
            {
                "name": "Rong Zhang",
                "org": "Key Lab of Bio-Resources and Eco-Environment, Ministry of Education, College of Life Science"
            },
            {
                "name": "Ming-ming Zhao",
                "org": "Key Lab of Bio-Resources and Eco-Environment, Ministry of Education, College of Life Science"
            },
            {
                "name": "Fang Chen",
                "org": "Key Lab of Bio-Resources and Eco-Environment, Ministry of Education, College of Life Science"
            },
            {
                "name": "Sheng-hua Wang",
                "org": "Key Lab of Bio-Resources and Eco-Environment, Ministry of Education, College of Life Science"
            }
        ],
        "title": "MicroRNA profiles and their control of male gametophyte development in rice",
        "keywords": [
            "Argonaute",
            "High-throughput sequencing",
            "Male gametophyte",
            "Microarray",
            "MicroRNAs",
            "Pollen development",
            "Rice"
        ],
        "venue": "Plant Molecular Biology",
        "year": 2012,
        "id": "9sRZb4ob"
    },
    "1euegKom": {
        "authors": [
            {
                "name": "Wen-Guo Wang",
                "org": "Key Lab of Bio-resources and Eco-environment"
            },
            {
                "name": "Sheng-Hua Wang",
                "org": "Key Lab of Bio-resources and Eco-environment"
            },
            {
                "name": "Xiao-Ai Wu",
                "org": "Key Lab of Bio-resources and Eco-environment"
            },
            {
                "name": "Xing-Yu Jin",
                "org": "Key Lab of Bio-resources and Eco-environment"
            },
            {
                "name": "Fang Chen",
                "org": "Key Lab of Bio-resources and Eco-environment"
            }
        ],
        "title": "High frequency plantlet regeneration from callus and artificial seed production of rock plant Pogonatherum paniceum (Lam.) Hack. (Poaceae)",
        "keywords": [
            "Artificial seeds",
            "Callus",
            "Pogonatherum paniceum",
            "Regeneration",
            "Rock plant",
            "Shoot buds"
        ],
        "venue": "Scientia Horticulturae",
        "year": 2007,
        "id": "1euegKom"
    },
    "jdYjsPX7": {
        "authors": [
            {
                "name": "Wenguo Wang",
                "org": "Key Lab of Bio-resources and Eco-environment"
            },
            {
                "name": "Xiaoguang Zhao",
                "org": "Key Lab of Bio-resources and Eco-environment"
            },
            {
                "name": "Guoqing Zhuang",
                "org": "Key Lab of Bio-resources and Eco-environment"
            },
            {
                "name": "Shenghua Wang",
                "org": "Key Lab of Bio-resources and Eco-environment"
            },
            {
                "name": "Fang Chen",
                "org": "Key Lab of Bio-resources and Eco-environment"
            }
        ],
        "title": "Simple hormonal regulation of somatic embryogenesis and/or shoot organogenesis in caryopsis cultures of Pogonatherum paniceum (Poaceae)",
        "keywords": [
            "Auxin",
            "Cytokinin",
            "Pogonatherum paniceum",
            "Shoot organogenesis",
            "Somatic embryogenesis"
        ],
        "venue": "Plant Cell, Tissue and Organ Culture",
        "year": 2008,
        "id": "jdYjsPX7"
    },
    "qaK2kVYT": {
        "authors": [
            {
                "name": "Yang He",
                "org": "Key Lab of Bio-resources and Eco-environment"
            },
            {
                "name": "Xiulian Guo",
                "org": "Key Lab of Bio-resources and Eco-environment"
            },
            {
                "name": "Ran Lu",
                "org": "Key Lab of Bio-resources and Eco-environment"
            },
            {
                "name": "Bei Niu",
                "org": "Key Lab of Bio-resources and Eco-environment"
            },
            {
                "name": "Vijaya Pasapula",
                "org": "Department of Biological Sciences"
            },
            {
                "name": "Pei Hou",
                "org": "Department of Biological Sciences"
            },
            {
                "name": "Feng Cai",
                "org": "Key Lab of Bio-resources and Eco-environment"
            },
            {
                "name": "Ying Xu",
                "org": "Key Lab of Bio-resources and Eco-environment"
            },
            {
                "name": "Fang Chen",
                "org": "Key Lab of Bio-resources and Eco-environment"
            }
        ],
        "title": "Changes in morphology and biochemical indices in browning callus derived from Jatropha curcas hypocotyls",
        "keywords": [
            "Browning",
            "Callus",
            "Jatropha curcas",
            "POD",
            "PPO",
            "Tissue culture"
        ],
        "venue": "Plant Cell, Tissue and Organ Culture",
        "year": 2009,
        "id": "qaK2kVYT"
    },
    "uKyqzZQQ": {
        "authors": [
            {
                "name": "Chun Li",
                "org": "Key Lab of Bio-resources and Eco-environment"
            },
            {
                "name": "Min Yu",
                "org": "Key Lab of Bio-resources and Eco-environment"
            },
            {
                "name": "Fang Chen",
                "org": "Key Lab of Bio-resources and Eco-environment"
            },
            {
                "name": "Shenghua Wang",
                "org": "Key Lab of Bio-resources and Eco-environment"
            }
        ],
        "title": "In vitro maturation and germination of jatropha curcas microspores",
        "keywords": [
            "Germination",
            "In vitro maturation",
            "Jatropha curcas",
            "Microspore",
            "Pollen"
        ],
        "venue": "International Journal of Agriculture and Biology",
        "year": 2010,
        "id": "uKyqzZQQ"
    },
    "ItFg9dw9": {
        "authors": [
            {
                "name": "Wen-Guo Wang",
                "org": ""
            },
            {
                "name": "Rui Li",
                "org": ""
            },
            {
                "name": "Bin Liu",
                "org": ""
            },
            {
                "name": "Liang Li",
                "org": ""
            },
            {
                "name": "Sheng-Hua Wang",
                "org": ""
            },
            {
                "name": "Fang Chen",
                "org": ""
            }
        ],
        "title": "Alternatively spliced transcripts of group 3 late embryogenesis abundant protein from Pogonatherum paniceum confer different abiotic stress tolerance in Escherichia coli",
        "keywords": [
            "Abiotic stress",
            "Alternatively splicing",
            "Escherichia coli",
            "Group 3 LEA protein",
            "Pogonatherum paniceum"
        ],
        "venue": "Journal of Plant Physiology",
        "year": 2012,
        "id": "ItFg9dw9"
    },
    "goQhM1i5": {
        "authors": [
            {
                "name": "Yang He",
                "org": "Key Lab. of Bio-Resources and Eco-Environment"
            },
            {
                "name": "Vijaya Pasapula",
                "org": "Department of Biological Sciences"
            },
            {
                "name": "Xiang Li",
                "org": "Key Lab. of Bio-Resources and Eco-Environment"
            },
            {
                "name": "Ran Lu",
                "org": "Key Lab. of Bio-Resources and Eco-Environment"
            },
            {
                "name": "Bei Niu",
                "org": "Key Lab. of Bio-Resources and Eco-Environment"
            },
            {
                "name": "Pei Hou",
                "org": "Department of Biological Sciences"
            },
            {
                "name": "Yi Wang",
                "org": "Key Lab. of Bio-Resources and Eco-Environment"
            },
            {
                "name": "Ying Xu",
                "org": "Key Lab. of Bio-Resources and Eco-Environment"
            },
            {
                "name": "Fang Chen",
                "org": "Key Lab. of Bio-Resources and Eco-Environment"
            }
        ],
        "title": "Agrobacterium tumefaciens-mediated transformation of Jatropha curcas: Factors affecting transient transformation efficiency and morphology analysis of transgenic calli",
        "keywords": [
            "Agrobacterium tumefaciens-mediated transformation",
            "Jatropha curcas",
            "Light microscopy",
            "Scanning electron microscopy"
        ],
        "venue": "Silvae Genetica",
        "year": 2009,
        "id": "goQhM1i5"
    },
    "lcQ7cwfo": {
        "authors": [
            {
                "name": "Jiang-Hui Bian",
                "org": "Key Laboratory of Adaptation and Evolution of Plateau Biota"
            },
            {
                "name": "Yan Wu",
                "org": "School of Life and Environment Sciences"
            },
            {
                "name": "Lowell L. Getz",
                "org": "Dept of Animal Biology"
            },
            {
                "name": "Yi-Fan Cao",
                "org": "Key Laboratory of Adaptation and Evolution of Plateau Biota"
            },
            {
                "name": "Fang Chen",
                "org": "School of Life and Environment Sciences"
            },
            {
                "name": "Le Yang",
                "org": "Key Laboratory of Adaptation and Evolution of Plateau Biota"
            }
        ],
        "title": "Does maternal stress influence winter survival of offspring in root voles Microtus oeconomus? A field experiment",
        "keywords": [
            ""
        ],
        "venue": "Oikos",
        "year": 2011,
        "id": "lcQ7cwfo"
    },
    "ZAhBLKrb": {
        "authors": [
            {
                "name": "Zhengyin Zhang",
                "org": "Key Laboratory of Bio-Resources and Eco-Environment"
            },
            {
                "name": "Boyang Liu",
                "org": "Key Laboratory of Bio-Resources and Eco-Environment"
            },
            {
                "name": "Fang Chen",
                "org": "Key Laboratory of Bio-Resources and Eco-Environment"
            },
            {
                "name": "Lin Tang",
                "org": "Key Laboratory of Bio-Resources and Eco-Environment"
            }
        ],
        "title": "Establishment of the optimized AFLP analysis system for Jatropha curcas",
        "keywords": [
            "AFLP",
            "DNA extraction CLC Q949.753.503",
            "Jatropha curcas",
            "Silver staining system"
        ],
        "venue": "Chinese Journal of Applied and Environmental Biology",
        "year": 2009,
        "id": "ZAhBLKrb"
    },
    "zJNEamWO": {
        "authors": [
            {
                "name": "Shaoyin Luo",
                "org": ""
            },
            {
                "name": "Jihai Gao",
                "org": ""
            },
            {
                "name": "Shengliang Ye",
                "org": ""
            },
            {
                "name": "Ying Xu",
                "org": ""
            },
            {
                "name": "Fang Chen",
                "org": ""
            }
        ],
        "title": "An improved SDS acid phenol method for total rna extraction from plant tissues rich in lipid",
        "keywords": [
            "Endosperm CLC Q949.753.506",
            "Jatropha curcas",
            "Oil",
            "SDS acid phenol method",
            "Total RNA"
        ],
        "venue": "Chinese Journal of Applied and Environmental Biology",
        "year": 2009,
        "id": "zJNEamWO"
    },
    "XwSDH6Zz": {
        "authors": [
            {
                "name": "Zeng-Bin Luo",
                "org": ""
            },
            {
                "name": "Xiao-Jia He",
                "org": ""
            },
            {
                "name": "Lin Chen",
                "org": ""
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                "name": "Xun-Lu Zhu",
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                "name": "Fang Chen",
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            {
                "name": "Lin Tang",
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            {
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            {
                "name": "Feng Cai",
                "org": "Key Laboratory of Bio-resources and Eco-environment"
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            {
                "name": "Xihong Zhu",
                "org": "Key Laboratory of Bio-resources and Eco-environment"
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            {
                "name": "Ying Xu",
                "org": "Key Laboratory of Bio-resources and Eco-environment"
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            {
                "name": "Fang Chen",
                "org": "Key Laboratory of Bio-resources and Eco-environment"
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            {
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                "org": "Key Laboratory of Bio-resources and Eco-environment"
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            {
                "name": "Shenghua Wang",
                "org": "Key Laboratory of Bio-resources and Eco-environment"
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            {
                "name": "Fang Chen",
                "org": "Key Laboratory of Bio-resources and Eco-environment"
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        "title": "Allelopathic potential of Jatropha curcas",
        "keywords": [
            "Allelopathy",
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            {
                "name": "Chao Ouyang",
                "org": "Key Laboratory of Bio-resources and Eco-environment"
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            {
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            {
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            {
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                "org": "Key Laboratory of Bio-resources and Eco-environment"
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            "Enzyme purification",
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            "Salt activation",
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        "authors": [
            {
                "name": "Liang Guo",
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            {
                "name": "Renwei Qing",
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            {
                "name": "Wei He",
                "org": "Key Laboratory of Bio-resources and Eco-environment of Education Ministry of China"
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            {
                "name": "Ying Xu",
                "org": "Key Laboratory of Bio-resources and Eco-environment of Education Ministry of China"
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                "org": "Key Laboratory of Bio-resources and Eco-environment of Education Ministry of China"
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            {
                "name": "Shenghua Wang",
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            {
                "name": "Fang Chen",
                "org": "Key Laboratory of Bio-resources and Eco-environment of Education Ministry of China"
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        ],
        "title": "Identification and characterization of a plastidial \u03c93-fatty acid desaturase gene from Jatropha curcas",
        "keywords": [
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            "Jatropha curcas",
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                "org": ""
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            {
                "name": "Fang Chen",
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        "title": "Genetic diversity and genetic relationship of Jatropha curcas between China and Southeast Asian revealed by amplified fragment length polymorphisms",
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            "Amplified fragment length polymorphism",
            "Genetic diversity",
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                "org": "Key Laboratory of Bio-resources and Eco-environment, Ministry of Education"
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                "org": "Key Laboratory of Bio-resources and Eco-environment, Ministry of Education"
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            {
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                "org": "Key Laboratory of Bio-resources and Eco-environment, Ministry of Education"
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                "org": "The Institute of Environmental and Human Health (TIEHH)"
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            {
                "name": "Fang Chen",
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        "title": "Cloning and expression analysis of carboxyltransferase of Acetyl-CoA carboxylase from Jatropha curcas",
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            "Fluorogenic quantitative real-time pcr",
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            {
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                "org": "Key Laboratory of Bio-resources and Eco-environment, Ministry of Education"
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                "org": "Key Laboratory of Bio-resources and Eco-environment, Ministry of Education"
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                "org": "Key Laboratory of Bio-resources and Eco-environment, Ministry of Education"
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            {
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                "org": "Key Laboratory of Bio-resources and Eco-environment, Ministry of Education"
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                "org": "Key Laboratory of Bio-resources and Eco-environment, Ministry of Education"
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        ],
        "title": "Cloning and characterization of a differentially expressed cDNA encoding myo-inositol-1-phosphate synthase involved in response to abiotic stress in Jatropha curcas",
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                "name": "Fang Chen",
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        "title": "A study on hydrogenation of diacetyl monoxime to tetramethylpyazine",
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            {
                "name": "Fang Chen",
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        "venue": "Analytical Letters",
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        "authors": [
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                "name": "Biyun Fang",
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            {
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            {
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            {
                "name": "Fang Chen",
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        "title": "Determination of ethylenediaminetetraacetic acid base on the reversion of fluorescence quenching of 2-pyridinecarbaldehyde-p-phenyldihydrazone by ferric iron",
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        "venue": "Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy",
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    "QgeSy3Iq": {
        "authors": [
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            {
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            {
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            {
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        "title": "Sensitive determination of DNA based on the interaction between prulifloxacin-terbium(III) complex and DNA",
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        "title": "Highly sensitive and selective determination of cupric ions by using N,N\u2032-bis(salicylidene)-o-phenylenediamine as fluorescent chemosensor and related applications",
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        "authors": [
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            {
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            {
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        "title": "Uranium(VI) Removal from Aqueous Solution by Poly(Amic Acid)-Modified Marine Fungus",
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            {
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            {
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                "org": "College of Environmental Science and Engineering"
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        "title": "Synthesis and evaluation of molecularly imprinted polymeric microspheres for highly selective extraction of an anti-AIDS drug emtricitabine",
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            {
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            },
            {
                "name": "Haoyi Yang",
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            {
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            },
            {
                "name": "Guoxiu Zhong",
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        "title": "Determination of Cd(II) in water samples by summable spectrophotometry of positive-negative peaks after cloud point extraction",
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        "venue": "Advanced Materials Research",
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        "authors": [
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                "name": "Lin Gao",
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            {
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                "org": "College of Arts and Sciences of Jianghan University"
            },
            {
                "name": "Fang Chen",
                "org": "School of Chemistry and Environmental Engineering"
            },
            {
                "name": "Jun Long Yao",
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        "title": "Spectrophotometric determination of Al(III) in environment water with p-Carboxyarsenazo",
        "keywords": [
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            "Environment",
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            "Spectrophotometry"
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        "venue": "Advanced Materials Research",
        "year": 2014,
        "id": "ZSdlzX9k"
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    "AlnEEwIJ": {
        "authors": [
            {
                "name": "Lin Gao",
                "org": "School of Chemistry and Environmental Engineering"
            },
            {
                "name": "Yan Hua Li",
                "org": "Key Laboratory of Optoelectronic Chemical Materials and Devices of Ministry of Education"
            },
            {
                "name": "Sheng Jie Chen",
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            },
            {
                "name": "Fang Chen",
                "org": "School of Chemistry and Environmental Engineering"
            },
            {
                "name": "Yuan Fang Zhang",
                "org": "Key Laboratory of Optoelectronic Chemical Materials and Devices of Ministry of Education"
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            {
                "name": "Jun Long Yao",
                "org": "School of Materials Science and Technology"
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        ],
        "title": "Synthesis and application of p-Carboxyarsenazo for spectrophotometric determination of Cu(II) in environment water",
        "keywords": [
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            "p-Carboxyarsenazo",
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            "Synthesis"
        ],
        "venue": "Advanced Materials Research",
        "year": 2014,
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        "authors": [
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                "name": "Lin Gao",
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            {
                "name": "Sheng Jie Chen",
                "org": "School of Chemistry and Environmental Engineering"
            },
            {
                "name": "Fang Chen",
                "org": "School of Chemistry and Environmental Engineering"
            },
            {
                "name": "Wen Hong Zhou",
                "org": "School of Chemistry and Environmental Engineering"
            },
            {
                "name": "Jun Long Yao",
                "org": "School of Materials Science and Technology"
            }
        ],
        "title": "Cloud point extraction and spectrophotometry determination of lead in environment water using 5-Br-PADAP",
        "keywords": [
            "5-Br-PADAP",
            "Cloud point extraction",
            "Lead",
            "Spectrophotometry"
        ],
        "venue": "Advanced Materials Research",
        "year": 2014,
        "id": "iy56DaBw"
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        "authors": [
            {
                "name": "Lian-Pei Zou",
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            {
                "name": "Rui-Ru Sun",
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            },
            {
                "name": "Jian-Yong Liu",
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            },
            {
                "name": "Fang Chen",
                "org": "School of Environmental and Chemical Engineering"
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            {
                "name": "Yao-Dong Huo",
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            {
                "name": "Zhi-Ming Wu",
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        "title": "Effects of sediments nutrition status on the growth of Potamogeton crispus",
        "keywords": [
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            "Suspension culture"
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        "authors": [
            {
                "name": "Zhen Rong",
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                "name": "Fang Chen",
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            {
                "name": "Hong Liu",
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            "Supersonic",
            "Wind tunnel test"
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        "venue": "Shiyan Liuti Lixue/Journal of Experiments in Fluid Mechanics",
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        "authors": [
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            {
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        "venue": "50th AIAA Aerospace Sciences Meeting Including the New Horizons Forum and Aerospace Exposition",
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            "Tracking capability"
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        "authors": [
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            {
                "name": "Fang Chen",
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        "authors": [
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                "name": "Shengtao Zhang",
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            {
                "name": "Fang Chen",
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                "name": "Hong Liu",
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        "title": "Numerical study of chemical nonequilibrium effect on aeroheating environment of hypersonic vehicles",
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            "TPS",
            "Wall catalysis"
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        "authors": [
            {
                "name": "Bin Zhang",
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            {
                "name": "Hong Liu",
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            },
            {
                "name": "Fang Chen",
                "org": "School of Aeronautics and Astronautics"
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            {
                "name": "Jian Hang Wang",
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            "Detonation",
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            "Reactive Euler equations",
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            "Stiff source term",
            "The equilibrium state method"
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        "venue": "Journal of Computational Physics",
        "year": 2014,
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        "venue": "32nd AIAA Applied Aerodynamics Conference",
        "year": 2014,
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        "authors": [
            {
                "name": "Shengtao Zhang",
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            {
                "name": "Fang Chen",
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            {
                "name": "Hong Liu",
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        "title": "Multi-field coupling numerical analysis approach for aerothermal environment of hypersonic vehicles",
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        "authors": [
            {
                "name": "Jianhang Wang",
                "org": "School of Aeronautics and Astronautics, Shanghai Jiaotong University"
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            {
                "name": "Fang Chen",
                "org": "School of Aeronautics and Astronautics, Shanghai Jiaotong University"
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            {
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            {
                "name": "Lan Wang",
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            {
                "name": "Zhonghua Zheng",
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        "title": "A shock-pinned random projection method for multi-directional stiff detonation capturing",
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        "venue": "Jisuan Wuli/Chinese Journal of Computational Physics",
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        "authors": [
            {
                "name": "Chulin Liang",
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            {
                "name": "Xiaosong Hu",
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            {
                "name": "Yuanying Ni",
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            {
                "name": "Jihong Wu",
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            {
                "name": "Fang Chen",
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            {
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        "title": "Effect of hydrocolloids on pulp sediment, white sediment, turbidity and viscosity of reconstituted carrot juice",
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        "authors": [
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                "name": "Yan Zhang",
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            {
                "name": "Xiaojun Liao",
                "org": "Laboratory of Horticultural Products Processing and Storage"
            },
            {
                "name": "Yuanying Ni",
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            },
            {
                "name": "Jihong Wu",
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            },
            {
                "name": "Xiaosong Hu",
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            },
            {
                "name": "Zhengfu Wang",
                "org": "Laboratory of Horticultural Products Processing and Storage"
            },
            {
                "name": "Fang Chen",
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        ],
        "title": "Kinetic analysis of the degradation and its color change of cyanidin-3-glucoside exposed to pulsed electric field",
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                "name": "Hou-Yin Wang",
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            {
                "name": "Yuan-Ying Ni",
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            {
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            {
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            {
                "name": "Xiao-Jun Liao",
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            {
                "name": "Fang Chen",
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            },
            {
                "name": "Zheng-Fu Wang",
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        ],
        "title": "Kinetics of amino acid loss in carrot juice concentrate during storage",
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            "Leading amino acid",
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        "year": 2007,
        "id": "yFvmmJns"
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        "authors": [
            {
                "name": "Yangzhao Sun",
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            },
            {
                "name": "Xiaojun Liao",
                "org": "Laboratory of Horticultural Products Processing and Storage"
            },
            {
                "name": "Zhengfu Wang",
                "org": "Laboratory of Horticultural Products Processing and Storage"
            },
            {
                "name": "Xiaosong Hu",
                "org": "Laboratory of Horticultural Products Processing and Storage"
            },
            {
                "name": "Fang Chen",
                "org": "Laboratory of Horticultural Products Processing and Storage"
            }
        ],
        "title": "Optimization of microwave-assisted extraction of anthocyanins in red raspberries and identification of anthocyanin of extracts using high-performance liquid chromatography - Mass spectrometry",
        "keywords": [
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            "Identification",
            "Microwave-assisted extraction (MAE)",
            "Red raspberry"
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        "year": 2007,
        "id": "4aKxbAIf"
    },
    "SZBkG2xd": {
        "authors": [
            {
                "name": "Fang Chen",
                "org": "Laboratory of Horticultural Products Processing and Storage"
            },
            {
                "name": "Yangzhao Sun",
                "org": "Laboratory of Horticultural Products Processing and Storage"
            },
            {
                "name": "Guanghua Zhao",
                "org": "Laboratory of Horticultural Products Processing and Storage"
            },
            {
                "name": "Xiaojun Liao",
                "org": "Laboratory of Horticultural Products Processing and Storage"
            },
            {
                "name": "Xiaosong Hu",
                "org": "Laboratory of Horticultural Products Processing and Storage"
            },
            {
                "name": "Jihong Wu",
                "org": "Laboratory of Horticultural Products Processing and Storage"
            },
            {
                "name": "Zhengfu Wang",
                "org": "Laboratory of Horticultural Products Processing and Storage"
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        "title": "Optimization of ultrasound-assisted extraction of anthocyanins in red raspberries and identification of anthocyanins in extract using high-performance liquid chromatography-mass spectrometry",
        "keywords": [
            "Anthocyanins (Acys)",
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            "Red raspberry",
            "Ultrasound-assisted extraction (UAE)"
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        "venue": "Ultrasonics Sonochemistry",
        "year": 2007,
        "id": "SZBkG2xd"
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        "authors": [
            {
                "name": "Yan Zhang",
                "org": "Laboratory of Horticultural Products Processing and Storage"
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            {
                "name": "Xiaojun Liao",
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            {
                "name": "Fang Chen",
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            {
                "name": "Jihong Wu",
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            },
            {
                "name": "Xiaosong Hu",
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        "title": "Isolation, identification, and color characterization of cyanidin-3-glucoside and cyanidin-3-sophoroside from red raspberry",
        "keywords": [
            "Color characterization",
            "Cyanidin-3-glucoside",
            "Cyanidin-3-sophoroside",
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            "Isolation"
        ],
        "venue": "European Food Research and Technology",
        "year": 2008,
        "id": "9VEPCuAp"
    },
    "yJE4udYd": {
        "authors": [
            {
                "name": "Yongjiang Yu",
                "org": "Department of Urology"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Urology"
            },
            {
                "name": "Juan Qi",
                "org": "Department of Urology"
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        ],
        "title": "Clinical analysis of 7 cases of prostate sarcoma",
        "keywords": [
            "Prognosis",
            "Prostatic neoplasms/diagnosis",
            "Sarcoma"
        ],
        "venue": "Chinese Journal of Andrology",
        "year": 2006,
        "id": "yJE4udYd"
    },
    "9JNfJQ2P": {
        "authors": [
            {
                "name": "Yun-Teng Huang",
                "org": "Department of Urology"
            },
            {
                "name": "Chuan-Zhong Ye",
                "org": "Department of Urology"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Urology"
            },
            {
                "name": "Juan Qi",
                "org": "Department of Urology"
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        ],
        "title": "Construction of bicistronic DNA vaccine expressing prostate-specific membrane antigen and granulocyte-macrophage colony-stimulating factor and determination of its activity",
        "keywords": [
            "DNA",
            "Granulocyte-macrophage colony-stimulating factor",
            "Prostate-specific membrane antigen",
            "Vaccine"
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        "venue": "Academic Journal of Second Military Medical University",
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        "id": "9JNfJQ2P"
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    "zJ7c5lgz": {
        "authors": [
            {
                "name": "Yingjian Zhu",
                "org": "Department of Urology"
            },
            {
                "name": "Min Ye",
                "org": "Department of Urology"
            },
            {
                "name": "Weiming Wang",
                "org": "Department of Urology"
            },
            {
                "name": "Haibo Shen",
                "org": "Department of Urology"
            },
            {
                "name": "Xiuhua Chang",
                "org": "Department of Urology"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Urology"
            },
            {
                "name": "Jun Qi",
                "org": "Department of Urology"
            },
            {
                "name": "Guohua Liu",
                "org": "Department of Urology"
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        ],
        "title": "The value of pressure-flow study in diagnosis for patients with benign prostatic hyperplasia",
        "keywords": [
            "Benign prostatic hyperplasia",
            "Bladder outlet obstruction index",
            "Urodynamics"
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        "venue": "Chinese Journal of Andrology",
        "year": 2006,
        "id": "zJ7c5lgz"
    },
    "MGz7vf3p": {
        "authors": [
            {
                "name": "Jianhua Chen",
                "org": "Department of Urology"
            },
            {
                "name": "Jun Chen",
                "org": "Department of Urology"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Urology"
            },
            {
                "name": "Jianhe Liu",
                "org": "Department of Urology"
            },
            {
                "name": "Xujun Sheng",
                "org": "Department of Urology"
            },
            {
                "name": "Weiming Wang",
                "org": "Department of Urology"
            },
            {
                "name": "Liang Kong",
                "org": "Department of Urology"
            },
            {
                "name": "Yichen Huang",
                "org": "Department of Urology"
            },
            {
                "name": "Yunteng Huang",
                "org": "Department of Urology"
            },
            {
                "name": "Jun Qi",
                "org": "Department of Urology"
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        ],
        "title": "Combination of transurethral pneumatic and ultrasound cystolithotripsy and transurethral resection of prostate in benign prostatic hyperplasia with bladder stones",
        "keywords": [
            "Benign prostatic hyperplasia",
            "Bladder stones",
            "Cystolithotripsy",
            "Transurethral resection of prostate"
        ],
        "venue": "Chinese Journal of Andrology",
        "year": 2007,
        "id": "MGz7vf3p"
    },
    "k3YQ12Mg": {
        "authors": [
            {
                "name": "Liang Zhang",
                "org": "Department of Urology"
            },
            {
                "name": "Jun Pan",
                "org": "Department of Urology"
            },
            {
                "name": "Quan Qi",
                "org": "Department of Urology"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Urology"
            },
            {
                "name": "Jian Kang",
                "org": "Department of Urology"
            }
        ],
        "title": "Mechanism of action of doxazosin induced apoptosis in prostate cancer PC-3 cell line",
        "keywords": [
            "Apoptosis",
            "Caspases",
            "Cell line, tumor",
            "Doxazosin",
            "Prostatic neoplasms"
        ],
        "venue": "Chinese Journal of Andrology",
        "year": 2007,
        "id": "k3YQ12Mg"
    },
    "C49kDb73": {
        "authors": [
            {
                "name": "Jun Chen",
                "org": "Department of Urology"
            },
            {
                "name": "Jun Qi",
                "org": "Department of Urology"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Urology"
            },
            {
                "name": "Ji-Hong Liu",
                "org": "Department of Urology"
            },
            {
                "name": "Tao Wang",
                "org": "Department of Urology"
            },
            {
                "name": "Jun Yang",
                "org": "Department of Urology"
            },
            {
                "name": "Chun-Ping Yin",
                "org": "Department of Pharmacy"
            }
        ],
        "title": "Relaxation mechanisms of neferine on the rabbit corpus cavernosum tissue in vitro",
        "keywords": [
            "Corpus cavernosum",
            "Neferine",
            "Relaxation"
        ],
        "venue": "Asian Journal of Andrology",
        "year": 2007,
        "id": "C49kDb73"
    },
    "N4ZTTlNb": {
        "authors": [
            {
                "name": "Bai-Song Chen",
                "org": "Department of Urology"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Urology"
            }
        ],
        "title": "Neovascularization and tissue engineering",
        "keywords": [
            ""
        ],
        "venue": "Journal of Clinical Rehabilitative Tissue Engineering Research",
        "year": 2007,
        "id": "N4ZTTlNb"
    },
    "yMj7w7BK": {
        "authors": [
            {
                "name": "Jun Qi",
                "org": "Department of Urology"
            },
            {
                "name": "Jian Kang",
                "org": "Department of Urology"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Urology"
            },
            {
                "name": "Jianhua Chen",
                "org": "Department of Urology"
            },
            {
                "name": "Liang Zhang",
                "org": "Department of Urology"
            },
            {
                "name": "Liang Kong",
                "org": "Department of Urology"
            },
            {
                "name": "Weiming Wang",
                "org": "Department of Urology"
            },
            {
                "name": "Qiang Bai",
                "org": "Department of Urology"
            }
        ],
        "title": "Clinical analysis of prostate cancer in PSA grey zone",
        "keywords": [
            "Diagnosis",
            "Grey zone",
            "Prostatic neoplasms"
        ],
        "venue": "Chinese Journal of Andrology",
        "year": 2007,
        "id": "yMj7w7BK"
    },
    "TvndixRo": {
        "authors": [
            {
                "name": "Jian Kang",
                "org": "Department of Urology"
            },
            {
                "name": "Hai-Bo Shen",
                "org": "Department of Urology"
            },
            {
                "name": "Liang Zhang",
                "org": "Department of Urology"
            },
            {
                "name": "Qiang Bai",
                "org": "Department of Urology"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Urology"
            },
            {
                "name": "Jun Qi",
                "org": "Department of Urology"
            }
        ],
        "title": "Incidental prostate cancer after transurethral resection of prostatea - A retrospective analysis of 24 cases",
        "keywords": [
            "Combined modality therapy",
            "Follow-up studies",
            "Prostate neoplasm",
            "Transurethral resection of prostate"
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        "venue": "Tumor",
        "year": 2007,
        "id": "TvndixRo"
    },
    "AT99o7Cj": {
        "authors": [
            {
                "name": "Jianhua Chen",
                "org": "Department of Urology"
            },
            {
                "name": "Jun Qi",
                "org": "Department of Urology"
            },
            {
                "name": "Yichen Huang",
                "org": "Department of Urology"
            },
            {
                "name": "Liang Zhang",
                "org": "Department of Urology"
            },
            {
                "name": "Liang Kong",
                "org": "Department of Urology"
            },
            {
                "name": "Weiming Wang",
                "org": "Department of Urology"
            },
            {
                "name": "Jian Kang",
                "org": "Department of Urology"
            },
            {
                "name": "Yunteng Huang",
                "org": "Department of Urology"
            },
            {
                "name": "Xujun Sheng",
                "org": "Department of Urology"
            },
            {
                "name": "Yongjiang Yu",
                "org": "Department of Urology"
            },
            {
                "name": "Haibo Shen",
                "org": "Department of Urology"
            },
            {
                "name": "Qiang Bai",
                "org": "Department of Urology"
            },
            {
                "name": "Jianhe Liu",
                "org": "Department of Urology"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Urology"
            },
            {
                "name": "Ming Ye",
                "org": "Department of Urology"
            }
        ],
        "title": "Clinical analysis of transurethral resection of prostate and transurethral electrovaporization of prostate: A retrospective study of 5346 cases",
        "keywords": [
            "Prostatic hyperplasia/surgery",
            "Transurethral resection of prostate"
        ],
        "venue": "Chinese Journal of Andrology",
        "year": 2008,
        "id": "AT99o7Cj"
    },
    "QPDMdFyX": {
        "authors": [
            {
                "name": "Liang Kong",
                "org": "Department of Urology"
            },
            {
                "name": "Qiang Bai",
                "org": "Department of Urology"
            },
            {
                "name": "Yichen Huang",
                "org": "Department of Urology"
            },
            {
                "name": "Jianhua Chen",
                "org": "Department of Urology"
            },
            {
                "name": "Jun Qi",
                "org": "Department of Urology"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Urology"
            }
        ],
        "title": "Combination therapy of \u03b1-blockers and antidepressive drug for treatment of CP/CPPS",
        "keywords": [
            "Adrenergic alpha-antagonists",
            "Antidepressive agents",
            "Prostatitis"
        ],
        "venue": "Chinese Journal of Andrology",
        "year": 2008,
        "id": "QPDMdFyX"
    },
    "Iu4KbQui": {
        "authors": [
            {
                "name": "Jun-Mei Zhou",
                "org": "Department of Urology"
            },
            {
                "name": "Feng-Ying Xing",
                "org": "Center for Developmental Biology"
            },
            {
                "name": "Jian-Jun Shi",
                "org": "Laboratory of Stem Cell Biology"
            },
            {
                "name": "Zhen-Fu Fang",
                "org": "Center for Developmental Biology"
            },
            {
                "name": "Xue-Jin Chen",
                "org": "Department of Laboratory Animal Science"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Urology"
            }
        ],
        "title": "Quality of embryonic bodies and seeding density effects on neural differentiation of mouse embryonic stem cells",
        "keywords": [
            "Cell density",
            "Embryonic bodies",
            "Embryonic stem cells",
            "Neural differentiation"
        ],
        "venue": "Cell Biology International",
        "year": 2008,
        "id": "Iu4KbQui"
    },
    "NTllYGjb": {
        "authors": [
            {
                "name": "Bai-Song Chen",
                "org": "Department of Urology"
            },
            {
                "name": "Sheng-Li Zhang",
                "org": "Department of Urology"
            },
            {
                "name": "Hong-Quan Geng",
                "org": "Department of Urology"
            },
            {
                "name": "Jun Pan",
                "org": "Department of Urology"
            },
            {
                "name": "Shao-Feng Wu",
                "org": "Department of Urology"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Urology"
            }
        ],
        "title": "Expression of vascular endothelial growth factor in endothelial progenitor cells following its expression vector construction",
        "keywords": [
            ""
        ],
        "venue": "Journal of Clinical Rehabilitative Tissue Engineering Research",
        "year": 2008,
        "id": "NTllYGjb"
    },
    "tFGlTFhW": {
        "authors": [
            {
                "name": "Baisong S. Chen",
                "org": ""
            },
            {
                "name": "Shengli L. Zhang",
                "org": ""
            },
            {
                "name": "Hongquan Geng",
                "org": ""
            },
            {
                "name": "Jun Pan",
                "org": ""
            },
            {
                "name": "Fang Chen",
                "org": ""
            }
        ],
        "title": "Ex vivo functional evaluation of isolated strips in BAMG tissue-engineered bladders",
        "keywords": [
            "Bladder acellular matrix grafts (BAMG)",
            "Bladder augmentation",
            "Functional evaluation",
            "Tissue engineering"
        ],
        "venue": "International Journal of Artificial Organs",
        "year": 2009,
        "id": "tFGlTFhW"
    },
    "Bv53qfAy": {
        "authors": [
            {
                "name": "Jian Kang",
                "org": "Department of Urology"
            },
            {
                "name": "Yan-Wei Sun",
                "org": "Department of Urology"
            },
            {
                "name": "Liang Zhang",
                "org": "Department of Urology"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Urology"
            },
            {
                "name": "Jun Qi",
                "org": "Department of Urology"
            }
        ],
        "title": "Effects of doxazosin in combination with low concentration of doxorubicin on apoptosis induction in prostate cancer cells",
        "keywords": [
            "Apoptosis",
            "Doxazosin",
            "Doxorubicin",
            "Prostate cancer"
        ],
        "venue": "Journal of Shanghai Jiaotong University (Medical Science)",
        "year": 2009,
        "id": "Bv53qfAy"
    },
    "C4vFsdLh": {
        "authors": [
            {
                "name": "Hai-Bo Shen",
                "org": "Department of Urology"
            },
            {
                "name": "Zhe Zhu",
                "org": "Department of Urology"
            },
            {
                "name": "Jun Pan",
                "org": "Shanghai Pediatric Medical Institute"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Urology"
            }
        ],
        "title": "Differentiation of amniotic fluid-derived fetal mesenchymal stem cells into osteoblasts",
        "keywords": [
            ""
        ],
        "venue": "Journal of Clinical Rehabilitative Tissue Engineering Research",
        "year": 2009,
        "id": "C4vFsdLh"
    },
    "O8ZBEC0T": {
        "authors": [
            {
                "name": "Qi-Jia Zhan",
                "org": "Department of Urology"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Urology"
            }
        ],
        "title": "Current status of tissue engineering in urology",
        "keywords": [
            "Clinical practice",
            "Tissue engineering",
            "Urology"
        ],
        "venue": "Journal of Shanghai Jiaotong University (Medical Science)",
        "year": 2009,
        "id": "O8ZBEC0T"
    },
    "lkI6eBxW": {
        "authors": [
            {
                "name": "Hai-Bo Shen",
                "org": "Department of Urology"
            },
            {
                "name": "Jun Pan",
                "org": "Department of Urology"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Urology"
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        ],
        "title": "Construction and evaluation of acellular matrix for ureter tissue engineering",
        "keywords": [
            ""
        ],
        "venue": "Journal of Clinical Rehabilitative Tissue Engineering Research",
        "year": 2009,
        "id": "lkI6eBxW"
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    "RYtrp6Uj": {
        "authors": [
            {
                "name": "Jun Qi",
                "org": "Department of Urology"
            },
            {
                "name": "Zhengqin Gu",
                "org": "Department of Urology"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Urology"
            },
            {
                "name": "Haibo Shen",
                "org": "Department of Urology"
            },
            {
                "name": "Jianhua Chen",
                "org": "Department of Urology"
            },
            {
                "name": "Liang Zhang",
                "org": "Department of Urology"
            },
            {
                "name": "Weiming Wang",
                "org": "Department of Urology"
            }
        ],
        "title": "Management of renal cell carcinoma with tumor thrombus in renal vein and the inferior vena cava",
        "keywords": [
            ""
        ],
        "venue": "Annals of Vascular Surgery",
        "year": 2010,
        "id": "RYtrp6Uj"
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    "vbXzqtu1": {
        "authors": [
            {
                "name": "Huaizheng Liu",
                "org": "Department of Urology"
            },
            {
                "name": "Jian Ding",
                "org": "Department of Urology"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Urology"
            },
            {
                "name": "Benyi Fan",
                "org": "Department of Urology"
            },
            {
                "name": "Ning Gao",
                "org": "Department of Urology"
            },
            {
                "name": "Zhongqing Yang",
                "org": "Department of Urology"
            },
            {
                "name": "Lin Qi",
                "org": "Department of Urology"
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        ],
        "title": "Increased expression of elongation factor-1\u03b1 is significantly correlated with poor prognosis of human prostate cancer",
        "keywords": [
            "Elongation factor-1\u03b1",
            "Immunohistochemical analysis",
            "Metastasis",
            "Prognosis",
            "Prostate cancer"
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        "venue": "Scandinavian Journal of Urology and Nephrology",
        "year": 2010,
        "id": "vbXzqtu1"
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    "JzXGx00s": {
        "authors": [
            {
                "name": "Yu-Long Pan",
                "org": "Department of Urology"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Urology"
            },
            {
                "name": "Jian Kanag",
                "org": "Department of Urology"
            },
            {
                "name": "Jun-Hao Liang",
                "org": "Department of Urology"
            }
        ],
        "title": "In vitro study of ablation of rat bladder epithelial tissues by femtosecond laser",
        "keywords": [
            "Endourology",
            "Femtosecond laser",
            "Plasma-mediated tissue ablation",
            "Urinary stricture"
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        "venue": "Journal of Shanghai Jiaotong University (Medical Science)",
        "year": 2011,
        "id": "JzXGx00s"
    },
    "4pfGIxN8": {
        "authors": [
            {
                "name": "Bai-Song Chen",
                "org": "Department of Urology"
            },
            {
                "name": "Hua Xie",
                "org": "Department of Urology"
            },
            {
                "name": "Sheng-Li Zhang",
                "org": "Department of Urology"
            },
            {
                "name": "Hong-Quan Geng",
                "org": "Department of Urology"
            },
            {
                "name": "Jun-Mei Zhou",
                "org": "Department of Urology"
            },
            {
                "name": "Jun Pan",
                "org": "Department of Urology"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Urology"
            }
        ],
        "title": "Tissue engineering of bladder using vascular endothelial growth factor gene-modified endothelial progenitor cells",
        "keywords": [
            "Bladder",
            "Endothelial progenitor cells (EPCs)",
            "Gene therapy",
            "Tissue engineering",
            "Vascular endothelial growth factor (VEGF)"
        ],
        "venue": "International Journal of Artificial Organs",
        "year": 2011,
        "id": "4pfGIxN8"
    },
    "N8kgy9MH": {
        "authors": [
            {
                "name": "Yafeng Shang",
                "org": "Department of Urology"
            },
            {
                "name": "Junmei Zhou",
                "org": "Department of Urology"
            },
            {
                "name": "Hua Xie",
                "org": "Department of Urology"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Urology"
            },
            {
                "name": "Lu Wang",
                "org": "Key Lab of Textile Science and Technology"
            },
            {
                "name": "Fujun Wang",
                "org": "Key Lab of Textile Science and Technology"
            },
            {
                "name": "Wenzu Wang",
                "org": "Key Lab of Textile Science and Technology"
            },
            {
                "name": "Ting Zou",
                "org": "Key Lab of Textile Science and Technology"
            }
        ],
        "title": "Preliminary investigation on a fibrous assembly degradable ureteral stent prototype in vitro",
        "keywords": [
            "fibrous assembly degradable ureteral stent",
            "in vitro degradation",
            "mechanical properties",
            "PGA",
            "PLGA"
        ],
        "venue": "Proceedings - 2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011",
        "year": 2011,
        "id": "N8kgy9MH"
    },
    "ERNIaGLb": {
        "authors": [
            {
                "name": "Xiaorong Ma",
                "org": "Department of Urology"
            },
            {
                "name": "Shengli Zhang",
                "org": "Department of Urology"
            },
            {
                "name": "Junmei Zhou",
                "org": "Tissue Engineering Laboratory, Xinhua Hospital"
            },
            {
                "name": "Baisong Chen",
                "org": "Tissue Engineering Laboratory, Xinhua Hospital"
            },
            {
                "name": "Yafeng Shang",
                "org": "Department of Urology"
            },
            {
                "name": "Tongbing Gao",
                "org": "Department of Urology"
            },
            {
                "name": "Xue Wang",
                "org": "Department of Urology"
            },
            {
                "name": "Hua Xie",
                "org": "Department of Urology"
            },
            {
                "name": "Fang Chen",
                "org": "Tissue Engineering Laboratory, Xinhua Hospital"
            }
        ],
        "title": "Clone-derived human AF-amniotic fluid stem cells are capable of skeletal myogenic differentiation in vitro and in vivo",
        "keywords": [
            "Amniotic fluid stem cells",
            "Cell therapy",
            "Co-culture",
            "Myoblasts",
            "Myogenesis",
            "Myogenic differentiation"
        ],
        "venue": "Journal of Tissue Engineering and Regenerative Medicine",
        "year": 2012,
        "id": "ERNIaGLb"
    },
    "ad4aJGpc": {
        "authors": [
            {
                "name": "Ya-Feng Shang",
                "org": "Department of Urology"
            },
            {
                "name": "Ting Zou",
                "org": "Key Laboratory of Textile Science and Technology"
            },
            {
                "name": "Ming-Qing Zhang",
                "org": "Department of Urology"
            },
            {
                "name": "Fu-Jun Wang",
                "org": "Key Laboratory of Textile Science and Technology"
            },
            {
                "name": "Jun-Mei Zhou",
                "org": "Department of Urology"
            },
            {
                "name": "Wen-Zu Wang",
                "org": "Key Laboratory of Textile Science and Technology"
            },
            {
                "name": "Hua Xie",
                "org": "Department of Urology"
            },
            {
                "name": "Lu Wang",
                "org": "Key Laboratory of Textile Science and Technology"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Urology"
            }
        ],
        "title": "In vitro degradation study of a braided thin-walled biodegradable ureteral stent",
        "keywords": [
            "Braided",
            "Degradable ureteral stent",
            "In vitro degradation",
            "Mechanical property",
            "PGA(polyglycolic acid)",
            "PLGA(copolymer of polylactic and polyglycolic acid)",
            "Thin-walled"
        ],
        "venue": "Journal of Donghua University (English Edition)",
        "year": 2012,
        "id": "ad4aJGpc"
    },
    "p0CswU5Y": {
        "authors": [
            {
                "name": "Ming Qing Zhang",
                "org": "Department of Urology, Shanghai Children's Hospital, Shanghai Jiao Tong University"
            },
            {
                "name": "Ting Zou",
                "org": "Key Laboratory of Textile Science and Technology of Ministry of Education, College of Textiles, Donghua University"
            },
            {
                "name": "Yi Chen Huang",
                "org": "Department of Urology, Shanghai Children's Hospital, Shanghai Jiao Tong University"
            },
            {
                "name": "Ya Feng Shang",
                "org": "Department of Urology, First Affiliated Hospital to Henan University of Science and Technology"
            },
            {
                "name": "Gang Gang Yang",
                "org": "Department of Urology, Shanghai Children's Hospital, Shanghai Jiao Tong University"
            },
            {
                "name": "Wen Zu Wang",
                "org": "Key Laboratory of Textile Science and Technology of Ministry of Education, College of Textiles, Donghua University"
            },
            {
                "name": "Jun Mei Zhou",
                "org": "Department of Urology, Shanghai Children's Hospital, Shanghai Jiao Tong University"
            },
            {
                "name": "Lu Wang",
                "org": "Key Laboratory of Textile Science and Technology of Ministry of Education, College of Textiles, Donghua University"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Urology, Shanghai Children's Hospital, Shanghai Jiao Tong University"
            },
            {
                "name": "Hua Xie",
                "org": "Department of Urology, Shanghai Children's Hospital, Shanghai Jiao Tong University"
            }
        ],
        "title": "Braided thin-walled biodegradable ureteral stent: Preliminary evaluation in a canine model",
        "keywords": [
            "Canine",
            "Polymers",
            "Stents",
            "Ureter"
        ],
        "venue": "International Journal of Urology",
        "year": 2014,
        "id": "p0CswU5Y"
    },
    "38VcpjUx": {
        "authors": [
            {
                "name": "Shengli Zhang",
                "org": "Department of Urology, Xinhua Hospital"
            },
            {
                "name": "Hongquan Geng",
                "org": "Tissue Engineering Laboratory, Xinhua Hospital"
            },
            {
                "name": "Hua Xie",
                "org": "Department of Urology, Shanghai Children's Hospital"
            },
            {
                "name": "Qiquan Wu",
                "org": "Department of Urology, Xinhua Hospital"
            },
            {
                "name": "Xiaorong Ma",
                "org": "Department of Urology, Xinhua Hospital"
            },
            {
                "name": "Junmei Zhou",
                "org": "Tissue Engineering Laboratory, Xinhua Hospital"
            },
            {
                "name": "Fang Chen",
                "org": "Tissue Engineering Laboratory, Xinhua Hospital"
            }
        ],
        "title": "The heterogeneity of cell subtypes from a primary culture of human amniotic fluid",
        "keywords": [
            "Cell subtypes",
            "Colony poculum",
            "Human amniotic fluid",
            "Isolation"
        ],
        "venue": "Cellular and Molecular Biology Letters",
        "year": 2010,
        "id": "38VcpjUx"
    },
    "GZJxPmiD": {
        "authors": [
            {
                "name": "Jian-Jun Li",
                "org": "Department of Cardiology"
            },
            {
                "name": "Cong-Xin Huang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Chun-Hong Fang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Cardiology"
            },
            {
                "name": "Hong Jiang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Qi-Zhu Tang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Geng-Shan Li",
                "org": "Department of Cardiology"
            }
        ],
        "title": "Circadian variation in ischemic threshold in patients with stable angina: Relation to plasma endothelin-1",
        "keywords": [
            ""
        ],
        "venue": "Angiology",
        "year": 2002,
        "id": "GZJxPmiD"
    },
    "EeT7plCD": {
        "authors": [
            {
                "name": "Shao-Ping Nie",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xiao-Hui Liu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xin Du",
                "org": "Department of Cardiology"
            },
            {
                "name": "Jun-Ping Kang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Qiang L\u00fc",
                "org": "Department of Cardiology"
            },
            {
                "name": "Jian-Zeng Dong",
                "org": "Department of Cardiology"
            },
            {
                "name": "Cheng-Xiong Gu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Fang-Jiong Huang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Yu-Jie Zhou",
                "org": "Department of Cardiology"
            },
            {
                "name": "Zhi-Zhong Li",
                "org": "Department of Cardiology"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Cardiology"
            },
            {
                "name": "Shu-Zheng L\u00fc",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xue-Si Wu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Chang-Sheng Ma",
                "org": "Department of Cardiology"
            }
        ],
        "title": "Profile of risk factors modification after coronary revascularization in patients with coronary artery disease",
        "keywords": [
            "Coronary artery disease",
            "Follow-up studies",
            "Myocardial revascularization",
            "Risk-factors"
        ],
        "venue": "National Medical Journal of China",
        "year": 2006,
        "id": "EeT7plCD"
    },
    "OT7Xhz6n": {
        "authors": [
            {
                "name": "Rong Hu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Chang-Sheng Ma",
                "org": "Department of Cardiology"
            },
            {
                "name": "Shao-Ping Nie",
                "org": "Department of Cardiology"
            },
            {
                "name": "Qiang L\u00fc",
                "org": "Department of Cardiology"
            },
            {
                "name": "Jun-Ping Kang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xin Du",
                "org": "Department of Cardiology"
            },
            {
                "name": "Yin Zhang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Ying-Chun Gao",
                "org": "Department of Cardiology"
            },
            {
                "name": "Li-Qun He",
                "org": "Department of Cardiology"
            },
            {
                "name": "Chang-Qi Jia",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xin-Min Liu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Jian-Zeng Dong",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xiao-Hui Liu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Cardiology"
            },
            {
                "name": "Yu-Jie Zhou",
                "org": "Department of Cardiology"
            },
            {
                "name": "Shu-Zheng L\u00fc",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xue-Si Wu",
                "org": "Department of Cardiology"
            }
        ],
        "title": "Effect of metabolic syndrome on prognosis and clinical characteristics of revascularization in patients with coronary artery disease",
        "keywords": [
            "Coronary artery disease",
            "Metabolic syndrome",
            "Revascularization"
        ],
        "venue": "Chinese Medical Journal",
        "year": 2006,
        "id": "OT7Xhz6n"
    },
    "k6jlJuZT": {
        "authors": [
            {
                "name": "Li-Qun He",
                "org": "Department of Cardiology"
            },
            {
                "name": "Chang-Sheng Ma",
                "org": "Department of Cardiology"
            },
            {
                "name": "Shao-Ping Nie",
                "org": "Department of Cardiology"
            },
            {
                "name": "Qiang L\u00fc",
                "org": "Department of Cardiology"
            },
            {
                "name": "Chang-Qi Jia",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xin Du",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xiao-Hui Liu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Jian-Zeng Dong",
                "org": "Department of Cardiology"
            },
            {
                "name": "Zhi-Zong Li",
                "org": "Department of Cardiology"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Cardiology"
            },
            {
                "name": "Yu-Jie Zhou",
                "org": "Department of Cardiology"
            },
            {
                "name": "Shu-Zheng L\u00fc",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xue-Si Wu",
                "org": "Department of Cardiology"
            }
        ],
        "title": "Impact of drug-eluting stents on transferring treatment with coronary surgical revascularization among patients initially admitted to department of internal medicine",
        "keywords": [
            "Drug-eluting stents",
            "Myocardial revascularization",
            "Transferring treatment"
        ],
        "venue": "National Medical Journal of China",
        "year": 2007,
        "id": "k6jlJuZT"
    },
    "88uyaCtx": {
        "authors": [
            {
                "name": "Qiang Zhang",
                "org": ""
            },
            {
                "name": "Chang-Sheng Ma",
                "org": ""
            },
            {
                "name": "Shao-Ping Nie",
                "org": ""
            },
            {
                "name": "Xin Du",
                "org": ""
            },
            {
                "name": "Qiang Lv",
                "org": ""
            },
            {
                "name": "Jun-Ping Kang",
                "org": ""
            },
            {
                "name": "Yin Zhang",
                "org": ""
            },
            {
                "name": "Rong Hu",
                "org": ""
            },
            {
                "name": "Chang-Qi Jia",
                "org": ""
            },
            {
                "name": "Xin-Min Liu",
                "org": ""
            },
            {
                "name": "Xiao-Hui Liu",
                "org": ""
            },
            {
                "name": "Jian-Zeng Dong",
                "org": ""
            },
            {
                "name": "Fang Chen",
                "org": ""
            },
            {
                "name": "Yu-Jie Zhou",
                "org": ""
            },
            {
                "name": "Shu-Zheng Lv",
                "org": ""
            },
            {
                "name": "Fang-Jiong Huang",
                "org": ""
            },
            {
                "name": "Cheng-Xiong Gu",
                "org": ""
            },
            {
                "name": "Xue-Si Wu",
                "org": ""
            }
        ],
        "title": "Prevalence and impact of renal insufficiency on clinical outcomes of patients undergoing coronary revascularization",
        "keywords": [
            "Chronic kidney disease",
            "Creatinine clearance",
            "End-stage renal disease",
            "Mortality",
            "Revascularization"
        ],
        "venue": "Circulation Journal",
        "year": 2007,
        "id": "88uyaCtx"
    },
    "5w8EJhcX": {
        "authors": [
            {
                "name": "Rong Hu",
                "org": ""
            },
            {
                "name": "Chang-Sheng Ma",
                "org": ""
            },
            {
                "name": "Shao-Ping Nie",
                "org": ""
            },
            {
                "name": "Qiang L\u00fc",
                "org": ""
            },
            {
                "name": "Jun-Ping Kang",
                "org": ""
            },
            {
                "name": "Xin Du",
                "org": ""
            },
            {
                "name": "Ying Zhang",
                "org": ""
            },
            {
                "name": "Ying-Chun Gao",
                "org": ""
            },
            {
                "name": "Li-Qun He",
                "org": ""
            },
            {
                "name": "Chang-Qi Jia",
                "org": ""
            },
            {
                "name": "Xin-Min Liu",
                "org": ""
            },
            {
                "name": "Jian-Zeng Dong",
                "org": ""
            },
            {
                "name": "Xiao-Hui Liu",
                "org": ""
            },
            {
                "name": "Fang Chen",
                "org": ""
            },
            {
                "name": "Yu-Jie Zhou",
                "org": ""
            },
            {
                "name": "Shu-Zheng L\u00fc",
                "org": ""
            },
            {
                "name": "Xue-Si Wu",
                "org": ""
            }
        ],
        "title": "Prognosis of metabolic syndrome in coronary artery disease patients of different genders",
        "keywords": [
            "Coronary artery disease",
            "Metabolic syndrome, gender"
        ],
        "venue": "National Medical Journal of China",
        "year": 2007,
        "id": "5w8EJhcX"
    },
    "LwCgEgN5": {
        "authors": [
            {
                "name": "Xin Du",
                "org": "Department of Cardiology"
            },
            {
                "name": "Jun-Ping Kang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Qiang L\u00fc",
                "org": "Department of Cardiology"
            },
            {
                "name": "Shao-Ping Nie",
                "org": "Department of Cardiology"
            },
            {
                "name": "Jia-Hui Wu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Yin Zhang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xiao-Hui Liu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Shu-Zheng L\u00fc",
                "org": "Department of Cardiology"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xue-Si Wu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Chang-Sheng Ma",
                "org": "Department of Cardiology"
            }
        ],
        "title": "Prevalence of unrecognized diabetes and risk factor control among patients with coronary heart disease and prognosis thereof",
        "keywords": [
            "Coronary Heart Disease",
            "Prognosis",
            "Risk Factors",
            "Unrecognized Diabetes"
        ],
        "venue": "National Medical Journal of China",
        "year": 2007,
        "id": "LwCgEgN5"
    },
    "on5kGLQR": {
        "authors": [
            {
                "name": "Bin Que",
                "org": "Department of Cardiology"
            },
            {
                "name": "Chang-Sheng Ma",
                "org": "Department of Cardiology"
            },
            {
                "name": "Shao-Ping Nie",
                "org": "Department of Cardiology"
            },
            {
                "name": "Jian-Zeng Dong",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xue-Si Wu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xiao-Hui Liu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Shu-Zheng L\u00fc",
                "org": "Department of Cardiology"
            },
            {
                "name": "Zhi-Zhong Li",
                "org": "Department of Cardiology"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Cardiology"
            },
            {
                "name": "Yu-Jie Zhou",
                "org": "Department of Cardiology"
            },
            {
                "name": "Cheng-Xiong Gu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Fang-Jiong Huang",
                "org": "Department of Cardiology"
            }
        ],
        "title": "Impact of chronic anemia on in - Hospital clinical outcome of revascularization in patients with coronary artery disease",
        "keywords": [
            "Chronic anemia",
            "Coronary artery bypass grafting",
            "Percutaneous coronary intervention",
            "Revascularization"
        ],
        "venue": "Chinese Critical Care Medicine",
        "year": 2007,
        "id": "on5kGLQR"
    },
    "NApB6jfk": {
        "authors": [
            {
                "name": "Xiao-Hui Liu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xin Du",
                "org": "Department of Cardiology"
            },
            {
                "name": "Jun-Ping Kang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Qiang L\u00fc",
                "org": "Department of Cardiology"
            },
            {
                "name": "Qiang Zhang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Shu-Zheng L\u00fc",
                "org": "Department of Cardiology"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Cardiology"
            },
            {
                "name": "Chang-Sheng Ma",
                "org": "Department of Cardiology"
            }
        ],
        "title": "Medical therapy in revascularized coronary artery disease patients",
        "keywords": [
            "Coronary artery disease",
            "Medicine",
            "Secondary preventive"
        ],
        "venue": "National Medical Journal of China",
        "year": 2008,
        "id": "NApB6jfk"
    },
    "8GgcnhMN": {
        "authors": [
            {
                "name": "Hong Jiang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Dongdong Zhao",
                "org": "Department of Cardiology"
            },
            {
                "name": "Bo Cui",
                "org": "Department of Cardiology"
            },
            {
                "name": "Zhibing Lu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Jingjun L\u00fc",
                "org": "Department of Cardiology"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Cardiology"
            },
            {
                "name": "Minwei Bao",
                "org": "Department of Cardiology"
            }
        ],
        "title": "Electrical restitution determined by epicardial contact mapping and surface electrocardiogram: its role in ventricular fibrillation inducibility in swine",
        "keywords": [
            "Electrical restitution",
            "Electrocardiography",
            "Ventricular fibrillation"
        ],
        "venue": "Journal of Electrocardiology",
        "year": 2008,
        "id": "8GgcnhMN"
    },
    "NVrD26Te": {
        "authors": [
            {
                "name": "Yan Qiao",
                "org": "Department of Cardiology"
            },
            {
                "name": "Changsheng Ma",
                "org": "Department of Cardiology"
            },
            {
                "name": "Shaoping Nie",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xiaohui Liu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Junping Kang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Qiang Lv",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xin Du",
                "org": "Department of Cardiology"
            },
            {
                "name": "Rong Hu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Yin Zhang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Changqi Jia",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xinmin Liu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Jianzeng Dong",
                "org": "Department of Cardiology"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Cardiology"
            },
            {
                "name": "Yujie Zhou",
                "org": "Department of Cardiology"
            },
            {
                "name": "Shuzheng Lv",
                "org": "Department of Cardiology"
            },
            {
                "name": "Fangjiong Huang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Chengxiong Gu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xuesi Wu",
                "org": "Department of Cardiology"
            }
        ],
        "title": "Twelve months clinical outcome of drug-eluting stents implantation or coronary artery bypass surgery for the treatment of diabetic patients with multivessel disease",
        "keywords": [
            ""
        ],
        "venue": "Clinical Cardiology",
        "year": 2009,
        "id": "NVrD26Te"
    },
    "kGaJWa7m": {
        "authors": [
            {
                "name": "Yan Qiao",
                "org": "Department of Cardiology"
            },
            {
                "name": "Changsheng Ma",
                "org": "Department of Cardiology"
            },
            {
                "name": "Shaoping Nie",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xiaohui Liu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Junping Kang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Qiang Lv",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xin Du",
                "org": "Department of Cardiology"
            },
            {
                "name": "Rong Hu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Yin Zhang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Changqi Jia",
                "org": "Department of Cardiology"
            },
            {
                "name": "Jiahui Wu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xinmin Liu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Jianzeng Dong",
                "org": "Department of Cardiology"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Cardiology"
            },
            {
                "name": "Yujie Zhou",
                "org": "Department of Cardiology"
            },
            {
                "name": "Shuzheng Lv",
                "org": "Department of Cardiology"
            },
            {
                "name": "Fangjiong Huang",
                "org": "Department of Cardiac Surgery"
            },
            {
                "name": "Chengxiong Gu",
                "org": "Department of Cardiac Surgery"
            },
            {
                "name": "Xuesi Wu",
                "org": "Department of Cardiology"
            }
        ],
        "title": "Percutaneous treatment with drug-eluting stent vs bypass surgery in patients suffering from chronic stable angina with multivessel disease involving significant proximal stenosis in left anterior descending artery",
        "keywords": [
            "Coronary artery bypass grafting",
            "Coronary artery disease",
            "Drug-eluting stent",
            "Percutaneous coronary intervention"
        ],
        "venue": "Circulation Journal",
        "year": 2009,
        "id": "kGaJWa7m"
    },
    "CHA71rI4": {
        "authors": [
            {
                "name": "Jun-Ping Kang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Chang-Sheng Ma",
                "org": "Department of Cardiology"
            },
            {
                "name": "Qiang L\u00fc",
                "org": "Department of Cardiology"
            },
            {
                "name": "Shao-Ping Nie",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xin-Min Liu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xiao-Hui Liu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xin Du",
                "org": "Department of Cardiology"
            },
            {
                "name": "Rong Hu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Jian-Zeng Dong",
                "org": "Department of Cardiology"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Cardiology"
            },
            {
                "name": "Shu-Zheng L\u00fc",
                "org": "Department of Cardiology"
            },
            {
                "name": "Cheng-Xiong Gu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Fang-Jiong Huang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xue-Si Wu",
                "org": "Department of Cardiology"
            }
        ],
        "title": "Impact of overweight on clinical outcomes in patients undergoing coronary revascularization",
        "keywords": [
            "Angioplasty",
            "Body mass index",
            "Heart failure, congestive"
        ],
        "venue": "National Medical Journal of China",
        "year": 2010,
        "id": "CHA71rI4"
    },
    "aDYbtJi7": {
        "authors": [
            {
                "name": "Rong Hu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Chang-Sheng Ma",
                "org": "Department of Cardiology"
            },
            {
                "name": "Shao-Ping Nie",
                "org": "Department of Cardiology"
            },
            {
                "name": "Qiang L\u00fc",
                "org": "Department of Cardiology"
            },
            {
                "name": "Jun-Ping Kang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xin Du",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xin-Min Liu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xiao-Hui Liu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Cardiology"
            },
            {
                "name": "Yu-Jie Zhou",
                "org": "Department of Cardiology"
            },
            {
                "name": "Shu-Zheng L\u00fc",
                "org": "Department of Cardiology"
            }
        ],
        "title": "Metabolic syndrome may be better at predicating the prognosis of coronary artery disease than other traditional cardiovascular risk factors",
        "keywords": [
            "Coronary artery disease",
            "Metabolic syndrome"
        ],
        "venue": "National Medical Journal of China",
        "year": 2010,
        "id": "aDYbtJi7"
    },
    "O3otOV3Z": {
        "authors": [
            {
                "name": "Rang Hu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Chang-Skeng Ma",
                "org": "Department of Cardiology"
            },
            {
                "name": "Qiang Lv",
                "org": "Department of Cardiology"
            },
            {
                "name": "Jun-Ping Kang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Shao-Ping Nie",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xin Du",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xin-Min Liu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xiao-Hui Liu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Cardiology"
            },
            {
                "name": "Yu-Jie Zhou",
                "org": "Department of Cardiology"
            },
            {
                "name": "Shu-Zheng Lv",
                "org": "Department of Cardiology"
            }
        ],
        "title": "The prognosis of coronary disease with different cardiovascular risk factors combined",
        "keywords": [
            "Coronary artery disease",
            "Metabolic syndrome",
            "Prognosis"
        ],
        "venue": "Chinese Journal of Emergency Medicine",
        "year": 2010,
        "id": "O3otOV3Z"
    },
    "zxuohIB5": {
        "authors": [
            {
                "name": "Xu Li",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xiao-Hui Liu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Shao-Ping Nie",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xin Du",
                "org": "Department of Cardiology"
            },
            {
                "name": "Qiang L\u00fc",
                "org": "Department of Cardiology"
            },
            {
                "name": "Jun-Ping Kang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Jian-Zeng Dong",
                "org": "Department of Cardiology"
            },
            {
                "name": "Cheng-Xiong Gu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Fang-Jiong Huang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Yu-Jie Zhou",
                "org": "Department of Cardiology"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Cardiology"
            },
            {
                "name": "Shu-Zheng L\u00fc",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xue-Si Wu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Chang-Sheng Ma",
                "org": "Department of Cardiology"
            }
        ],
        "title": "Prognostic value of baseline C-reactive protein levels in patients undergoing coronary revascularization",
        "keywords": [
            "C reactive protein",
            "Coronary heart disease",
            "Prognosis",
            "Revascularization"
        ],
        "venue": "Chinese Medical Journal",
        "year": 2010,
        "id": "zxuohIB5"
    },
    "kQjIlQtV": {
        "authors": [
            {
                "name": "Wei Liu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Chang-Sheng Ma",
                "org": "Department of Cardiology"
            },
            {
                "name": "Jun-Ping Kang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xin Du",
                "org": "Department of Cardiology"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Cardiology"
            },
            {
                "name": "Yu-Jie Zhou",
                "org": "Department of Cardiology"
            },
            {
                "name": "Shu-Zheng L\u00fc",
                "org": "Department of Cardiology"
            },
            {
                "name": "Fang-Jiong Huang",
                "org": "Department of Cardiac Surgery"
            },
            {
                "name": "Cheng-Xiong Gu",
                "org": "Department of Cardiac Surgery"
            },
            {
                "name": "Xiao-Ling Zhu",
                "org": "Department of Cardiology"
            }
        ],
        "title": "Comparison of drug eluting stent implantation with coronary artery bypass surgery in the treatment of patients with chronic total occlusion and multiple vessel disease",
        "keywords": [
            "Cardiopulmonary bypass",
            "Chronic total occlusion",
            "Complete revascularization",
            "Drug eluting stent"
        ],
        "venue": "Chinese Medical Journal",
        "year": 2011,
        "id": "kQjIlQtV"
    },
    "BQOkSK73": {
        "authors": [
            {
                "name": "Qingmiao Yang",
                "org": ""
            },
            {
                "name": "Shuzheng Lu",
                "org": ""
            },
            {
                "name": "Yundai Chen",
                "org": ""
            },
            {
                "name": "Xiantao Song",
                "org": ""
            },
            {
                "name": "Zening Jin",
                "org": ""
            },
            {
                "name": "Fei Yuan",
                "org": ""
            },
            {
                "name": "Hong Li",
                "org": ""
            },
            {
                "name": "Yujie Zhou",
                "org": ""
            },
            {
                "name": "Fang Chen",
                "org": ""
            },
            {
                "name": "Yong Huo",
                "org": ""
            }
        ],
        "title": "Plasma osteoprotegerin levels and long-term prognosis in patients with intermediate coronary artery lesions",
        "keywords": [
            ""
        ],
        "venue": "Clinical Cardiology",
        "year": 2011,
        "id": "BQOkSK73"
    },
    "OeOqj0fM": {
        "authors": [
            {
                "name": "Min Zhang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Shuzheng Lu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xiaofan Wu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Yundai Chen",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xiantao Song",
                "org": "Department of Cardiology"
            },
            {
                "name": "Zening Jin",
                "org": "Department of Cardiology"
            },
            {
                "name": "Hong Li",
                "org": "Department of Cardiology"
            },
            {
                "name": "Yujie Zhou",
                "org": "Department of Cardiology"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Cardiology"
            },
            {
                "name": "Yong Huo",
                "org": "Department of Cardiology"
            }
        ],
        "title": "Multimarker approach for the prediction of cardiovascular events in patients with mild to moderate coronary artery lesions a 3-year follow-up study",
        "keywords": [
            "Mild to moderate lesions",
            "Multimarker score",
            "Risk factors"
        ],
        "venue": "International Heart Journal",
        "year": 2012,
        "id": "OeOqj0fM"
    },
    "7dGUczOy": {
        "authors": [
            {
                "name": "Zeng-Ming Xue",
                "org": "Department of Cardiology"
            },
            {
                "name": "Wei-Ju Li",
                "org": "Department of Cardiology"
            },
            {
                "name": "Chang-Sheng Ma",
                "org": "Department of Cardiology"
            },
            {
                "name": "Shao-Ping Nie",
                "org": "Department of Cardiology"
            },
            {
                "name": "Jian-Zeng Dong",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xiao-Hui Liu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Jun-Ping Kang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Qiang L\u00fc",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xin Du",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xiao Wang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Cardiology"
            },
            {
                "name": "Yu-Jie Zhou",
                "org": "Department of Cardiology"
            },
            {
                "name": "Shu-Zheng L\u00fc",
                "org": "Department of Cardiology"
            },
            {
                "name": "Fang-Jiong Huang",
                "org": "Department of Cardiac Surgery"
            },
            {
                "name": "Cheng-Xiong Gu",
                "org": "Department of Cardiac Surgery"
            },
            {
                "name": "Xue-Si Wu",
                "org": "Department of Cardiology"
            }
        ],
        "title": "Coronary stenting versus bypass surgery in heart failure patients with preserved ejection fraction",
        "keywords": [
            "Coronary artery disease",
            "Heart failure",
            "Revascularization"
        ],
        "venue": "Chinese Medical Journal",
        "year": 2012,
        "id": "7dGUczOy"
    },
    "Mk2wCSTl": {
        "authors": [
            {
                "name": "Yawei Luo",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xianpeng Yu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xin Du",
                "org": "Department of Cardiology"
            },
            {
                "name": "Jiqiang He",
                "org": "Department of Cardiology"
            },
            {
                "name": "Yuechun Gao",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xiaoling Zhang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Yuchen Zhang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xuejun Ren",
                "org": "Department of Cardiology"
            },
            {
                "name": "Shuzheng Lv",
                "org": "Department of Cardiology"
            },
            {
                "name": "Changsheng Ma",
                "org": "Department of Cardiology"
            }
        ],
        "title": "Impact of diabetes mellitus on patients with unprotected left main coronary artery lesion disease treated with either percutaneous coronary intervention or coronary-artery bypass grafting",
        "keywords": [
            "coronary-artery bypass grafting",
            "diabetes",
            "percutaneous coronary intervention",
            "unprotected left main coronary artery disease"
        ],
        "venue": "Coronary Artery Disease",
        "year": 2012,
        "id": "Mk2wCSTl"
    },
    "bIECTZnS": {
        "authors": [
            {
                "name": "Xianpeng Yu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Cardiology"
            },
            {
                "name": "Jiqiang He",
                "org": "Department of Cardiology"
            },
            {
                "name": "Yuechun Gao",
                "org": "Department of Cardiology"
            },
            {
                "name": "Changyan Wu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Yawei Luo",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xiaoling Zhang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Yuchen Zhang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xuejun Ren",
                "org": "Department of Cardiology"
            },
            {
                "name": "Shuzheng Lv",
                "org": "Department of Cardiology"
            }
        ],
        "title": "Duration of dual antiplatelet therapy after implantation of the first-generation and second-generation drug-eluting stents",
        "keywords": [
            ""
        ],
        "venue": "Coronary Artery Disease",
        "year": 2013,
        "id": "bIECTZnS"
    },
    "rCR0lu8G": {
        "authors": [
            {
                "name": "Yan-Hong Li",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xue-Jun Ren",
                "org": "Department of Cardiology"
            },
            {
                "name": "Zhi-Hong Han",
                "org": "Department of Cardiology"
            },
            {
                "name": "Yun-Long Wang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Ye Wang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Jin-Rong Zhang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Cardiology"
            }
        ],
        "title": "Value of the frontal planar QRS-T angle on cardiac dysfunction in patients with old myocardial infarction",
        "keywords": [
            "Cardiac dysfunction",
            "Old myocardial infarction",
            "Planar QRS-T angle"
        ],
        "venue": "International Journal of Clinical and Experimental Medicine",
        "year": 2013,
        "id": "rCR0lu8G"
    },
    "xWkHLg67": {
        "authors": [
            {
                "name": "Yu Xu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Yanan Shi",
                "org": "Department of Cardiology"
            },
            {
                "name": "Zhongyu Zhu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Changhe Cui",
                "org": "Department of Cardiology"
            },
            {
                "name": "Bei Li",
                "org": "Department of Cardiology"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Cardiology"
            },
            {
                "name": "Dan Li",
                "org": "Department of Cardiology"
            },
            {
                "name": "Songhu Chen",
                "org": "Department of Cardiology"
            },
            {
                "name": "Yang Guo",
                "org": "Department of Cardiology"
            }
        ],
        "title": "Prognosis of patients with heart failure and reduced ejection fraction in China",
        "keywords": [
            "Heart failure",
            "Left ventricular ejection fraction",
            "Medication status quo",
            "Prognosis"
        ],
        "venue": "Experimental and Therapeutic Medicine",
        "year": 2013,
        "id": "xWkHLg67"
    },
    "AApnfUJ2": {
        "authors": [
            {
                "name": "Bo Xu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Runlin Gao",
                "org": "Department of Cardiology"
            },
            {
                "name": "Jian'An Wang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Yuejin Yang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Shaoliang Chen",
                "org": "Department of Cardiology"
            },
            {
                "name": "Bin Liu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Cardiology"
            },
            {
                "name": "Zhanquan Li",
                "org": "Department of Cardiology"
            },
            {
                "name": "Yaling Han",
                "org": "Department of Cardiology"
            },
            {
                "name": "Guosheng Fu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Yelin Zhao",
                "org": "Department of Cardiology"
            },
            {
                "name": "Junbo Ge",
                "org": "Department of Cardiology"
            }
        ],
        "title": "A prospective, multicenter, randomized trial of paclitaxel-coated balloon versus paclitaxel-eluting stent for the treatment of drug-eluting stent in-stent restenosis: Results from the PEPCAD China ISR trial",
        "keywords": [
            "in-stent restenosis",
            "paclitaxel-coated balloon(s)",
            "paclitaxel-eluting stent(s)"
        ],
        "venue": "JACC: Cardiovascular Interventions",
        "year": 2014,
        "id": "AApnfUJ2"
    },
    "Bhd30wGb": {
        "authors": [
            {
                "name": "Quan Li",
                "org": "Department of Cardiology, Beijing An Zhen Hospital, Capital Medical University"
            },
            {
                "name": "Xianpeng Yu",
                "org": "Department of Cardiology, Beijing An Zhen Hospital, Capital Medical University"
            },
            {
                "name": "Jiqiang He",
                "org": "Department of Cardiology, Beijing An Zhen Hospital, Capital Medical University"
            },
            {
                "name": "Yuechun Gao",
                "org": "Department of Cardiology, Beijing An Zhen Hospital, Capital Medical University"
            },
            {
                "name": "Xiaoling Zhang",
                "org": "Department of Cardiology, Beijing An Zhen Hospital, Capital Medical University"
            },
            {
                "name": "Changyan Wu",
                "org": "Department of Cardiology, Beijing An Zhen Hospital, Capital Medical University"
            },
            {
                "name": "Yawei Luo",
                "org": "Department of Cardiology, Beijing An Zhen Hospital, Capital Medical University"
            },
            {
                "name": "Yuchen Zhang",
                "org": "Department of Cardiology, Beijing An Zhen Hospital, Capital Medical University"
            },
            {
                "name": "Xuejun Ren",
                "org": "Department of Cardiology, Beijing An Zhen Hospital, Capital Medical University"
            },
            {
                "name": "Shuzheng Lv",
                "org": "Department of Cardiology, Beijing An Zhen Hospital, Capital Medical University"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Cardiology, Beijing An Zhen Hospital, Capital Medical University"
            }
        ],
        "title": "The relationship between revascularization extent and the long-term prognosis of patients with stable angina pectoris and three-vessel disease treated by percutaneous coronary intervention in the era of drug-eluting stents",
        "keywords": [
            ""
        ],
        "venue": "Clinical Cardiology",
        "year": 2014,
        "id": "Bhd30wGb"
    },
    "6tuEcccg": {
        "authors": [
            {
                "name": "Yu Li",
                "org": ""
            },
            {
                "name": "Fang Chen",
                "org": ""
            },
            {
                "name": "Xiaoling Zhang",
                "org": ""
            },
            {
                "name": "Yuechun Gao",
                "org": ""
            },
            {
                "name": "Changyan Wu",
                "org": ""
            },
            {
                "name": "Haiyan Li",
                "org": ""
            },
            {
                "name": "Yuchen Zhang",
                "org": ""
            }
        ],
        "title": "Angiotensin type 1 receptor A1166C gene polymorphism is associated with endothelial dysfunction and in-stent restenosis after percutaneous coronary intervention",
        "keywords": [
            "Angiotensin type 1 receptor",
            "In-stent restenosis",
            "Percutaneous coronary intervention",
            "Polymorphism"
        ],
        "venue": "International Journal of Clinical and Experimental Pathology",
        "year": 2015,
        "id": "6tuEcccg"
    },
    "3vhbbA73": {
        "authors": [
            {
                "name": "Ji-Qiang He",
                "org": "Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University and Institution of Beijing Heart Lung and Vascular Disease"
            },
            {
                "name": "Xian-Peng Yu",
                "org": "Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University and Institution of Beijing Heart Lung and Vascular Disease"
            },
            {
                "name": "Cheng Peng",
                "org": "Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University and Institution of Beijing Heart Lung and Vascular Disease"
            },
            {
                "name": "Quan Li",
                "org": "Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University and Institution of Beijing Heart Lung and Vascular Disease"
            },
            {
                "name": "Ya-Wei Luo",
                "org": "Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University and Institution of Beijing Heart Lung and Vascular Disease"
            },
            {
                "name": "Yue-Chun Gao",
                "org": "Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University and Institution of Beijing Heart Lung and Vascular Disease"
            },
            {
                "name": "Xiao-Ling Zhang",
                "org": "Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University and Institution of Beijing Heart Lung and Vascular Disease"
            },
            {
                "name": "Chang-Yan Wu",
                "org": "Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University and Institution of Beijing Heart Lung and Vascular Disease"
            },
            {
                "name": "Hua Zhao",
                "org": "Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University and Institution of Beijing Heart Lung and Vascular Disease"
            },
            {
                "name": "Yu-Chen Zhang",
                "org": "Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University and Institution of Beijing Heart Lung and Vascular Disease"
            },
            {
                "name": "Jing-Hua Liu",
                "org": "Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University and Institution of Beijing Heart Lung and Vascular Disease"
            },
            {
                "name": "Shu-Zheng Lyu",
                "org": "Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University and Institution of Beijing Heart Lung and Vascular Disease"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University and Institution of Beijing Heart Lung and Vascular Disease"
            }
        ],
        "title": "Predictive ability of the SYNergy between percutaneous coronary intervention with TAXus and cardiac surgery score II for long-term mortality in patients with three-vessel coronary artery disease undergoing percutaneous coronary intervention treated with second-generation drug-eluting stents",
        "keywords": [
            "Mortality",
            "Percutaneous coronary intervention",
            "Predictive ability",
            "Second-generation drug-eluting stents",
            "SYNTAX score II",
            "Three-vessel coronary artery disease"
        ],
        "venue": "Chinese Medical Journal",
        "year": 2015,
        "id": "3vhbbA73"
    },
    "YRF5W7sv": {
        "authors": [
            {
                "name": "Ji-Qiang He",
                "org": "Department of Cardiology, Beijing an Zhen Hospital"
            },
            {
                "name": "Yue-Chun Gao",
                "org": "Department of Cardiology, Beijing an Zhen Hospital"
            },
            {
                "name": "Xian-Peng Yu",
                "org": "Department of Cardiology, Beijing an Zhen Hospital"
            },
            {
                "name": "Xiao-Ling Zhang",
                "org": "Department of Cardiology, Beijing an Zhen Hospital"
            },
            {
                "name": "Ya-Wei Luo",
                "org": "Department of Cardiology, Beijing an Zhen Hospital"
            },
            {
                "name": "Chang-Yan Wu",
                "org": "Department of Cardiology, Beijing an Zhen Hospital"
            },
            {
                "name": "Yu Li",
                "org": "Department of Cardiology, Beijing an Zhen Hospital"
            },
            {
                "name": "Wei-Dong Zhang",
                "org": "Department of Cardiology, Beijing an Zhen Hospital"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Cardiology, Beijing an Zhen Hospital"
            },
            {
                "name": "Shu-Zheng L\u00fc",
                "org": "Department of Cardiology, Beijing an Zhen Hospital"
            }
        ],
        "title": "Syntax score predicts clinical outcome in patients with three-vessel coronary artery disease undergoing percutaneous coronary intervention",
        "keywords": [
            "3-vessel coronary artery disease",
            "Percutaneous coronary intervention",
            "Syntax score"
        ],
        "venue": "Chinese Medical Journal",
        "year": 2011,
        "id": "YRF5W7sv"
    },
    "VCKWD8BH": {
        "authors": [
            {
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                "org": "Department of Cardiology, Capital University of Medical Science, Beijing Institute of Heart Lung and Blood Vessel Disease"
            },
            {
                "name": "Zhi-Hong Han",
                "org": "Department of Cardiology, Capital University of Medical Science, Beijing Institute of Heart Lung and Blood Vessel Disease"
            },
            {
                "name": "Yun-Long Wang",
                "org": "Department of Cardiology, Capital University of Medical Science, Beijing Institute of Heart Lung and Blood Vessel Disease"
            },
            {
                "name": "Ye Wang",
                "org": "Department of Cardiology, Capital University of Medical Science, Beijing Institute of Heart Lung and Blood Vessel Disease"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Cardiology, Capital University of Medical Science, Beijing Institute of Heart Lung and Blood Vessel Disease"
            }
        ],
        "title": "Electrophysiological characteristics of ventriculoa- Trial conduction during slow pathway ablation in atrioventricular nodal reentrant tachycardia",
        "keywords": [
            "Atrioventricular nodal reentrant tachycardia",
            "Junctional rhythm",
            "Radiofrequency ablation"
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    },
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        "authors": [
            {
                "name": "Hou-Yin Wang",
                "org": "College of Food Science"
            },
            {
                "name": "Xiao-Song Hu",
                "org": "College of Food Science"
            },
            {
                "name": "Fang Chen",
                "org": "College of Food Science"
            },
            {
                "name": "Ji-Hong Wu",
                "org": "College of Food Science"
            },
            {
                "name": "Zheng-Hua Zhang",
                "org": "College of Food Science"
            },
            {
                "name": "Xiao-Jun Liao",
                "org": "College of Food Science"
            },
            {
                "name": "Zheng-Fu Wang",
                "org": "College of Food Science"
            }
        ],
        "title": "Kinetic analysis of non-enzymatic browning in carrot juice concentrate during storage",
        "keywords": [
            "5-Hydroxymethylfurfural (HMF)",
            "Browning degree (BD)",
            "Carrot juice concentrate (CJC)",
            "The first-order reaction",
            "Total soluble solid"
        ],
        "venue": "European Food Research and Technology",
        "year": 2006,
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    },
    "LdoocDDQ": {
        "authors": [
            {
                "name": "Yuanyuan Zhang",
                "org": "College of Food Science"
            },
            {
                "name": "Zhe Zhang",
                "org": "Key Laboratory of Animal Genetics and Breeding"
            },
            {
                "name": "Fang Chen",
                "org": "Key Laboratory of Fruits and Vegetables Processing"
            },
            {
                "name": "Hui Zhang",
                "org": "Key Laboratory of Fruits and Vegetables Processing"
            },
            {
                "name": "Xiaosong Hu",
                "org": "Key Laboratory of Fruits and Vegetables Processing"
            }
        ],
        "title": "Effect of sonication on eliminating of phorate in apple juice",
        "keywords": [
            "Apple juice",
            "Degradation products",
            "Phorate",
            "Quality analysis",
            "Sonication"
        ],
        "venue": "Ultrasonics Sonochemistry",
        "year": 2012,
        "id": "LdoocDDQ"
    },
    "rnYW0a6w": {
        "authors": [
            {
                "name": "Yuanyuan Zhang",
                "org": "College of Food Science"
            },
            {
                "name": "Yaxi Hou",
                "org": "College of Food Science and Nutritional Engineering, Key Lab. of Fruits and Vegetables Processing"
            },
            {
                "name": "Yan Zhang",
                "org": "College of Food Science and Nutritional Engineering, Key Lab. of Fruits and Vegetables Processing"
            },
            {
                "name": "Jie Chen",
                "org": "The Laboratory of the Advanced Technology of Electrical Engineering and Energy"
            },
            {
                "name": "Fang Chen",
                "org": "College of Food Science and Nutritional Engineering, Key Lab. of Fruits and Vegetables Processing"
            },
            {
                "name": "Xiaojun Liao",
                "org": "College of Food Science and Nutritional Engineering, Key Lab. of Fruits and Vegetables Processing"
            },
            {
                "name": "Xiaosong Hu",
                "org": "College of Food Science and Nutritional Engineering, Key Lab. of Fruits and Vegetables Processing"
            }
        ],
        "title": "Reduction of diazinon and dimethoate in apple juice by pulsed electric field treatment",
        "keywords": [
            "Degradation",
            "Diazinon",
            "Dimethoate",
            "Kinetics",
            "Pulsed electric field (PEF)",
            "Toxicity"
        ],
        "venue": "Journal of the Science of Food and Agriculture",
        "year": 2012,
        "id": "rnYW0a6w"
    },
    "njkfUZLo": {
        "authors": [
            {
                "name": "Fangyu Long",
                "org": "College of Food Science and Engineering, Northwest A and F University"
            },
            {
                "name": "Xin Yang",
                "org": "College of Animal Science and Technology, Northwest A and F University"
            },
            {
                "name": "Rongrong Wang",
                "org": "College of Food Science and Nutritional Engineering, Ministry of Agriculture, National Engineering Research Center for Fruits and Vegetables Processing"
            },
            {
                "name": "Xiaosong Hu",
                "org": "College of Food Science and Nutritional Engineering, Ministry of Agriculture, National Engineering Research Center for Fruits and Vegetables Processing"
            },
            {
                "name": "Fang Chen",
                "org": "College of Food Science and Nutritional Engineering, Ministry of Agriculture, National Engineering Research Center for Fruits and Vegetables Processing"
            }
        ],
        "title": "Effects of combined high pressure and thermal treatments on the allergenic potential of shrimp (Litopenaeus vannamei) tropomyosin in a mouse model of allergy",
        "keywords": [
            "High-pressure processing",
            "Shrimp",
            "Tropomyosin"
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    "Ap1hyeOs": {
        "authors": [
            {
                "name": "Fang Chen",
                "org": "College of Food Science and Nutrition Engineering"
            },
            {
                "name": "Xiaojun Liao",
                "org": "College of Food Science and Nutrition Engineering"
            },
            {
                "name": "Zhengfu Wang",
                "org": "College of Food Science and Nutrition Engineering"
            },
            {
                "name": "Tongyi Cai",
                "org": "College of Food Science and Nutrition Engineering"
            },
            {
                "name": "Xiaosong Hu",
                "org": "College of Food Science and Nutrition Engineering"
            }
        ],
        "title": "Effect of process parameters on the refining of higher fatty alcohol extracts during molecular distillation",
        "keywords": [
            "Higher fatty alcohol",
            "Molecular distillation",
            "Refining"
        ],
        "venue": "Nongye Gongcheng Xuebao/Transactions of the Chinese Society of Agricultural Engineering",
        "year": 2005,
        "id": "Ap1hyeOs"
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    "Bw61TwyB": {
        "authors": [
            {
                "name": "Mengyao Zhao",
                "org": "College of Food Science and Nutritional Eng., Natl. Eng. Res. Centre for Fruits and Veg. Process., Key Laboratory of Fruits and Vegetables Processing, Ministry of Agriculture, Eng. Res. Centre for Fruits and Vegetables Process., Ministry of Education, China Agricultural Univ"
            },
            {
                "name": "Xin Liu",
                "org": "College of Food Science and Nutritional Eng., Natl. Eng. Res. Centre for Fruits and Veg. Process., Key Laboratory of Fruits and Vegetables Processing, Ministry of Agriculture, Eng. Res. Centre for Fruits and Vegetables Process., Ministry of Education, China Agricultural Univ"
            },
            {
                "name": "Yinghua Luo",
                "org": "Dept. of Nutrition and Food Science, Univ. of Maryland"
            },
            {
                "name": "Huan Guo",
                "org": "College of Food Science and Nutritional Eng., Natl. Eng. Res. Centre for Fruits and Veg. Process., Key Laboratory of Fruits and Vegetables Processing, Ministry of Agriculture, Eng. Res. Centre for Fruits and Vegetables Process., Ministry of Education, China Agricultural Univ"
            },
            {
                "name": "Xiaosong Hu",
                "org": "College of Food Science and Nutritional Eng., Natl. Eng. Res. Centre for Fruits and Veg. Process., Key Laboratory of Fruits and Vegetables Processing, Ministry of Agriculture, Eng. Res. Centre for Fruits and Vegetables Process., Ministry of Education, China Agricultural Univ"
            },
            {
                "name": "Fang Chen",
                "org": "College of Food Science and Nutritional Eng., Natl. Eng. Res. Centre for Fruits and Veg. Process., Key Laboratory of Fruits and Vegetables Processing, Ministry of Agriculture, Eng. Res. Centre for Fruits and Vegetables Process., Ministry of Education, China Agricultural Univ"
            }
        ],
        "title": "Evaluation of Protective Effect of Freeze-Dried Strawberry, Grape, and Blueberry Powder on Acrylamide Toxicity in Mice",
        "keywords": [
            "Acrylamide (AA)",
            "Berry powder",
            "General toxicity",
            "Genetic toxicity",
            "Protection",
            "Reproductive toxicity"
        ],
        "venue": "Journal of Food Science",
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    },
    "cVYoLK8s": {
        "authors": [
            {
                "name": "Bing Bai",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Fang Chen",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Zhengfu Wang",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaojun Liao",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Guanghua Zhao",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaosong Hu",
                "org": "College of Food Science and Nutritional Engineering"
            }
        ],
        "title": "Mechanism of the greening color formation of \"Laba\" garlic, a traditional homemade Chinese food product",
        "keywords": [
            "\"Laba\"",
            "Acetic acid",
            "Alliinase",
            "Color formation",
            "Garlic",
            "Greening",
            "Thiosulfinates"
        ],
        "venue": "Journal of Agricultural and Food Chemistry",
        "year": 2005,
        "id": "cVYoLK8s"
    },
    "xwUgxarT": {
        "authors": [
            {
                "name": "Kui Zhong",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Fang Chen",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Zhengfu Wang",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Jihong Wu",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaojun Liao",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaosong Hu",
                "org": "College of Food Science and Nutritional Engineering"
            }
        ],
        "title": "Inactivation and kinetic model for the Escherichia coli treated by a co-axial pulsed electric field",
        "keywords": [
            "Carrot juice",
            "Escherichia coli",
            "Inactivation",
            "Inactivation kinetics",
            "Pulsed electric field"
        ],
        "venue": "European Food Research and Technology",
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        "id": "xwUgxarT"
    },
    "tfnxg5fy": {
        "authors": [
            {
                "name": "Liyan Zhao",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Fang Chen",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Guanghua Zhao",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Zhengfu Wang",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaojun Liao",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaosong Hu",
                "org": "College of Food Science and Nutritional Engineering"
            }
        ],
        "title": "Isomerization of trans-astaxanthin induced by copper(II) ion in ethanol",
        "keywords": [
            "Astaxanthin",
            "Carotenoids",
            "Cu(II)",
            "Isomerization"
        ],
        "venue": "Journal of Agricultural and Food Chemistry",
        "year": 2005,
        "id": "tfnxg5fy"
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    "shdp0Pl7": {
        "authors": [
            {
                "name": "Kui Zhong",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Fang Chen",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "W.U. Jihong",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Zhengfu Wang",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaojun Liao",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "H.U. Xiaosong",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Zhenhua Zhang",
                "org": "College of Food Science and Nutritional Engineering"
            }
        ],
        "title": "Kinetics of inactivation of escherichia coli in carrot juice by pulsed electric field",
        "keywords": [
            ""
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        "venue": "Journal of Food Process Engineering",
        "year": 2005,
        "id": "shdp0Pl7"
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    "EfG9GdB1": {
        "authors": [
            {
                "name": "Fenqi Gui",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Zhengfu Wang",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Jihong Wu",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Fang Chen",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaojun Liao",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaosong Hu",
                "org": "College of Food Science and Nutritional Engineering"
            }
        ],
        "title": "Inactivation and reactivation of horseradish peroxidase treated with supercritical carbon dioxide",
        "keywords": [
            "D value",
            "Horseradish peroxidase (HRP)",
            "Inactivation",
            "Reactivation",
            "Supercritical carbon dioxide (SCCO 2)"
        ],
        "venue": "European Food Research and Technology",
        "year": 2006,
        "id": "EfG9GdB1"
    },
    "DXhFVfhb": {
        "authors": [
            {
                "name": "Fenqi Gui",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Jihong Wu",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Fang Chen",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaojun Liao",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaosong Hu",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Zhenhua Zhang",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Zhengfu Wang",
                "org": "College of Food Science and Nutritional Engineering"
            }
        ],
        "title": "Change of polyphenol oxidase activity, color, and browning degree during storage of cloudy apple juice treated by supercritical carbon dioxide",
        "keywords": [
            "Browning degree",
            "Color",
            "Polyphenol oxidase (PPO)",
            "Supercritical carbon dioxide (SCCO2)"
        ],
        "venue": "European Food Research and Technology",
        "year": 2006,
        "id": "DXhFVfhb"
    },
    "CRsIHpUy": {
        "authors": [
            {
                "name": "Zhengfu Wang",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Yongkun Ma",
                "org": "College of Biological and Environmental Engineering"
            },
            {
                "name": "Guanghua Zhao",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaojun Liao",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Fang Chen",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Jihong Wu",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Jiluan Chen",
                "org": "School of Chemistry and Chemical Engineering"
            },
            {
                "name": "Xiaosong Hu",
                "org": "College of Food Science and Nutritional Engineering"
            }
        ],
        "title": "Influence of gamma irradiation on enzyme, microorganism, and flavor of cantaloupe (Cucumis melo L.) juice",
        "keywords": [
            "Cantaloupe juice",
            "Enzyme activity",
            "Gamma irradiation",
            "Inactivation",
            "Microorganism",
            "Off-odor"
        ],
        "venue": "Journal of Food Science",
        "year": 2006,
        "id": "CRsIHpUy"
    },
    "CqSmHLYT": {
        "authors": [
            {
                "name": "Fenqi Gui",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Fang Chen",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Jihong Wu",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Zhengfu Wang",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaojun Liao",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaosong Hu",
                "org": "College of Food Science and Nutritional Engineering"
            }
        ],
        "title": "Inactivation and structural change of horseradish peroxidase treated with supercritical carbon dioxide",
        "keywords": [
            "Far UV-circular dichroism",
            "Horseradish peroxidase",
            "Inactivation",
            "Supercritical carbon dioxide",
            "Tryptophan fluorescence spectroscopy"
        ],
        "venue": "Food Chemistry",
        "year": 2006,
        "id": "CqSmHLYT"
    },
    "rXHH7VJ0": {
        "authors": [
            {
                "name": "Liyan Zhao",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Guanghua Zhao",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Fang Chen",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Zhengfu Wang",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Jihong Wu",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaosong Hu",
                "org": "College of Food Science and Nutritional Engineering"
            }
        ],
        "title": "Different effects of microwave and ultrasound on the stability of (all-E)-astaxanthin",
        "keywords": [
            "Astaxanthin",
            "Carotenoids",
            "Degradation",
            "Isomerization",
            "Microwave",
            "Ultrasound"
        ],
        "venue": "Journal of Agricultural and Food Chemistry",
        "year": 2006,
        "id": "rXHH7VJ0"
    },
    "g0xZVTO5": {
        "authors": [
            {
                "name": "Ying Sun",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Zhengfu Wang",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Jihong Wu",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Fang Chen",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaojun Liao",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaosong Hu",
                "org": "College of Food Science and Nutritional Engineering"
            }
        ],
        "title": "Optimising enzymatic maceration in pretreatment of carrot juice concentrate by response surface methodology",
        "keywords": [
            "Carrot",
            "Central composite rotatable design",
            "Enzymatic maceration",
            "Response surface methodology"
        ],
        "venue": "International Journal of Food Science and Technology",
        "year": 2006,
        "id": "g0xZVTO5"
    },
    "zAX1dMrL": {
        "authors": [
            {
                "name": "Kui Zhong",
                "org": ""
            },
            {
                "name": "Jihong Wu",
                "org": ""
            },
            {
                "name": "Zhengfu Wang",
                "org": ""
            },
            {
                "name": "Fang Chen",
                "org": ""
            },
            {
                "name": "Xiaojun Liao",
                "org": ""
            },
            {
                "name": "Xiaosong Hu",
                "org": ""
            },
            {
                "name": "Zhenhua Zhang",
                "org": ""
            }
        ],
        "title": "Inactivation kinetics and secondary structural change of PEF-treated POD and PPO",
        "keywords": [
            "Circular dichroism",
            "Peroxidase",
            "Polyphenol oxidase",
            "Pulsed electric fields"
        ],
        "venue": "Food Chemistry",
        "year": 2007,
        "id": "zAX1dMrL"
    },
    "CfvGdCxD": {
        "authors": [
            {
                "name": "Zhengfu Wang",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Junhong Sun",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaojun Liao",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Fang Chen",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Guanghua Zhao",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Jihong Wu",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaosong Hu",
                "org": "College of Food Science and Nutritional Engineering"
            }
        ],
        "title": "Mathematical modeling on hot air drying of thin layer apple pomace",
        "keywords": [
            "Activation energy",
            "Apple pomace",
            "Drying rate",
            "Effective diffusivity",
            "Hot air convective drying",
            "Modeling"
        ],
        "venue": "Food Research International",
        "year": 2007,
        "id": "CfvGdCxD"
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    "r7ccJvBR": {
        "authors": [
            {
                "name": "Fenqi Gui",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Jihong Wu",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Fang Chen",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaojun Liao",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaosong Hu",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Zhenghua Zhang",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Zhengfu Wang",
                "org": "College of Food Science and Nutritional Engineering"
            }
        ],
        "title": "Inactivation of polyphenol oxidases in cloudy apple juice exposed to supercritical carbon dioxide",
        "keywords": [
            "Cloudy apple juice",
            "First-order reaction",
            "Inactivation",
            "Polyphenol oxidase",
            "Supercritical carbon dioxide"
        ],
        "venue": "Food Chemistry",
        "year": 2007,
        "id": "r7ccJvBR"
    },
    "wrB5x2V5": {
        "authors": [
            {
                "name": "Sijin Wang",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Fang Chen",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Jihong Wu",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Zhengfu Wang",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaojun Liao",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaosong Hu",
                "org": "College of Food Science and Nutritional Engineering"
            }
        ],
        "title": "Optimization of pectin extraction assisted by microwave from apple pomace using response surface methodology",
        "keywords": [
            "Apple pomace",
            "Microwave-assisted extraction (MAE)",
            "Pectin extraction",
            "Response surface methodology"
        ],
        "venue": "Journal of Food Engineering",
        "year": 2007,
        "id": "wrB5x2V5"
    },
    "bLSlHbtS": {
        "authors": [
            {
                "name": "Jihong Wu",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Haiyan Gao",
                "org": "School of Life Science"
            },
            {
                "name": "Lei Zhao",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaojun Liao",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Fang Chen",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Zhenfu Wang",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaosong Hu",
                "org": "College of Food Science and Nutritional Engineering"
            }
        ],
        "title": "Chemical compositional characterization of some apple cultivars",
        "keywords": [
            "Apple cultivars",
            "Chemical composition",
            "Gas-chromatography",
            "High-performance liquid chromatography"
        ],
        "venue": "Food Chemistry",
        "year": 2007,
        "id": "bLSlHbtS"
    },
    "ybaYhuPI": {
        "authors": [
            {
                "name": "Zhengfu Wang",
                "org": ""
            },
            {
                "name": "Han Wu",
                "org": ""
            },
            {
                "name": "Guanghua Zhao",
                "org": ""
            },
            {
                "name": "Xiaojun Liao",
                "org": ""
            },
            {
                "name": "Fang Chen",
                "org": ""
            },
            {
                "name": "Jihong Wu",
                "org": ""
            },
            {
                "name": "Xiaosong Hu",
                "org": ""
            }
        ],
        "title": "One-dimensional finite-difference modeling on temperature history and freezing time of individual food",
        "keywords": [
            "Apparent heat capacity approach",
            "Freezing time",
            "Individually quick freezing",
            "Mathematical model",
            "Quadratic curve"
        ],
        "venue": "Journal of Food Engineering",
        "year": 2007,
        "id": "ybaYhuPI"
    },
    "9GkUP1cl": {
        "authors": [
            {
                "name": "Fang Chen",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Zhengfu Wang",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Guanghua Zhao",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaojun Liao",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Tongyi Cai",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Linyu Guo",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaosong Hu",
                "org": "College of Food Science and Nutritional Engineering"
            }
        ],
        "title": "Purification process of octacosanol extracts from rice bran wax by molecular distillation",
        "keywords": [
            "Molecular distillation (MD)",
            "Octacosanol",
            "Purification",
            "Rice bran wax (RBW)"
        ],
        "venue": "Journal of Food Engineering",
        "year": 2007,
        "id": "9GkUP1cl"
    },
    "zmEIPyVX": {
        "authors": [
            {
                "name": "Zhengfu Wang",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Junhong Sun",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Fang Chen",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaojun Liao",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaosong Hu",
                "org": "College of Food Science and Nutritional Engineering"
            }
        ],
        "title": "Mathematical modelling on thin layer microwave drying of apple pomace with and without hot air pre-drying",
        "keywords": [
            "Apple pomace",
            "Drying rate",
            "Effective diffusivity",
            "Microwave drying",
            "Modelling"
        ],
        "venue": "Journal of Food Engineering",
        "year": 2007,
        "id": "zmEIPyVX"
    },
    "EpT9bK0V": {
        "authors": [
            {
                "name": "Hongmei Liao",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Ying Sun",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Yuanying Ni",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaojun Liao",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaosong Hu",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Jihong Wu",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Fang Chen",
                "org": "College of Food Science and Nutritional Engineering"
            }
        ],
        "title": "The effect of enzymatic mash treatment, pressing, centrifugation, homogenization, deaeration, sterilization and storage on carrot juice",
        "keywords": [
            ""
        ],
        "venue": "Journal of Food Process Engineering",
        "year": 2007,
        "id": "EpT9bK0V"
    },
    "bFCxuWEO": {
        "authors": [
            {
                "name": "Li-ying NIU",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Ji-hong WU",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiao-jun LIAO",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Fang CHEN",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Zheng-fu WANG",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Guang-hua ZHAO",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiao-song HU",
                "org": "College of Food Science and Nutritional Engineering"
            }
        ],
        "title": "Physicochemical Characteristics of Orange Juice Samples From Seven Cultivars",
        "keywords": [
            "China",
            "orange cultivars",
            "physicochemical characteristics"
        ],
        "venue": "Agricultural Sciences in China",
        "year": 2008,
        "id": "bFCxuWEO"
    },
    "DUow44qb": {
        "authors": [
            {
                "name": "Dan Wang",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Husile Nanding",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Na Han",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Fang Chen",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Guanghua Zhao",
                "org": "College of Food Science and Nutritional Engineering"
            }
        ],
        "title": "2-(1H-pyrrolyl)carboxylic acids as pigment precursors in garlic greening",
        "keywords": [
            "2-(1H-pyrrolyl)carboxylic acids",
            "Di(2-propenyl) thiosulfinate",
            "Garlic greening",
            "Pigment precursor",
            "Pyruvic acid",
            "Thiosulfinate"
        ],
        "venue": "Journal of Agricultural and Food Chemistry",
        "year": 2008,
        "id": "DUow44qb"
    },
    "TVmHvvkg": {
        "authors": [
            {
                "name": "Lei Li",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Dan Hu",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Ying Jiang",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Fang Chen",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaosong Hu",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Guanghua Zhao",
                "org": "College of Food Science and Nutritional Engineering"
            }
        ],
        "title": "Relationship between \u03b3-glutamyl transpeptidase activity and garlic greening, as controlled by temperature",
        "keywords": [
            "\u03b3-glutamyl transpeptidase",
            "Garlic",
            "Greening",
            "Storage",
            "Thiosulfinates"
        ],
        "venue": "Journal of Agricultural and Food Chemistry",
        "year": 2008,
        "id": "TVmHvvkg"
    },
    "bR87YTqC": {
        "authors": [
            {
                "name": "Yuan Yuan",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Guang-Hua Zhao",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiao-Song Hu",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Ji-Hong Wu",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Jie Liu",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Fang Chen",
                "org": "College of Food Science and Nutritional Engineering"
            }
        ],
        "title": "High correlation of methylglyoxal with acrylamide formation in glucose/asparagine Maillard reaction model",
        "keywords": [
            "\u03b1-Dicarbonyl compounds",
            "Acrylamide (AA)",
            "Asparagine (Asn)",
            "Glucose (Glc)",
            "Maillard reaction (MR)",
            "Methylglyoxal (MG)"
        ],
        "venue": "European Food Research and Technology",
        "year": 2008,
        "id": "bR87YTqC"
    },
    "gqiEqqFa": {
        "authors": [
            {
                "name": "Jie Liu",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Ganghua Zhao",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Yuan Yuan",
                "org": "College of Quartermaster Technology"
            },
            {
                "name": "Fang Chen",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaosong Hu",
                "org": "College of Food Science and Nutritional Engineering"
            }
        ],
        "title": "Quantitative analysis of acrylamide in tea by liquid chromatography coupled with electrospray ionization tandem mass spectrometry",
        "keywords": [
            "Acrylamide",
            "Liquid chromatography-tandem mass spectrometry (LC-MS/MS)",
            "Quantitative analysis",
            "Tea"
        ],
        "venue": "Food Chemistry",
        "year": 2008,
        "id": "gqiEqqFa"
    },
    "zgl1U6z8": {
        "authors": [
            {
                "name": "Fang Chen",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Lingqin Zeng",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Yuanyuan Zhang",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaojun Liao",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Yiqiang Ge",
                "org": "China Rural Technology Development Center"
            },
            {
                "name": "Xiaosong Hu",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Lianzhou Jiang",
                "org": "College of Food Science"
            }
        ],
        "title": "Degradation behaviour of methamidophos and chlorpyrifos in apple juice treated with pulsed electric fields",
        "keywords": [
            "Apple juice",
            "Chlorpyrifos",
            "Degradation",
            "Methamidophos",
            "Pulsed electric field (PEF)"
        ],
        "venue": "Food Chemistry",
        "year": 2009,
        "id": "zgl1U6z8"
    },
    "hNeyFVX3": {
        "authors": [
            {
                "name": "Zhengfu Wang",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Han Wu",
                "org": "Chinese Academy of Agricultural Mechanization Sciences"
            },
            {
                "name": "Guanghua Zhao",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaojun Liao",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Fang Chen",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Jihong Wu",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaosong Hu",
                "org": "College of Food Science and Nutritional Engineering"
            }
        ],
        "title": "Corrigendum to \"One-dimensional finite difference modeling on temperature history and freezing time of individual food\" [Journal of Food Engineering 79/2 (2007) 502-510] (DOI:10.1016/j.jfoodeng.2006.02.012)",
        "keywords": [
            ""
        ],
        "venue": "Journal of Food Engineering",
        "year": 2009,
        "id": "hNeyFVX3"
    },
    "kLxc6Klr": {
        "authors": [
            {
                "name": "Yuanyuan Zhang",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Zhiyong Xiao",
                "org": "Beijing Agro-Environmental Monitoring Station"
            },
            {
                "name": "Fang Chen",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Yiqiang Ge",
                "org": "China Rural Technology Development Center"
            },
            {
                "name": "Jihong Wu",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaosong Hu",
                "org": "College of Food Science and Nutritional Engineering"
            }
        ],
        "title": "Degradation behavior and products of malathion and chlorpyrifos spiked in apple juice by ultrasonic treatment",
        "keywords": [
            "Apple juice",
            "Chlorpyrifos",
            "Degradation",
            "Malathion",
            "Reaction kinetics",
            "Ultrasonic treatment"
        ],
        "venue": "Ultrasonics Sonochemistry",
        "year": 2010,
        "id": "kLxc6Klr"
    },
    "JfIeZ6KO": {
        "authors": [
            {
                "name": "Lingling Li",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Zhengfu Wang",
                "org": ""
            },
            {
                "name": "Xiaosong Hu",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Jihong Wu",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaojun Liao",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Fang Chen",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Guanghua Zhao",
                "org": "College of Food Science and Nutritional Engineering"
            }
        ],
        "title": "Drying effects of two air-drying shelters in a pilot test on sultana grapes",
        "keywords": [
            ""
        ],
        "venue": "Journal of Food Process Engineering",
        "year": 2010,
        "id": "JfIeZ6KO"
    },
    "d5vBd1g3": {
        "authors": [
            {
                "name": "Yuanyuan Zhang",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Wenjia Zhang",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaojun Liao",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Jianing Zhang",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Yaxi Hou",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Zhiyong Xiao",
                "org": "Beijing Agro-Environmental Monitoring Station"
            },
            {
                "name": "Fang Chen",
                "org": "National Soybean Engineering Research Center"
            },
            {
                "name": "Xiaosong Hu",
                "org": "College of Food Science and Nutritional Engineering"
            }
        ],
        "title": "Degradation of diazinon in apple juice by ultrasonic treatment",
        "keywords": [
            "Apple juice",
            "Degradation",
            "Diazinon",
            "Products",
            "Ultrasonic treatment"
        ],
        "venue": "Ultrasonics Sonochemistry",
        "year": 2010,
        "id": "d5vBd1g3"
    },
    "fQ8y0GMg": {
        "authors": [
            {
                "name": "Lin Li",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Lun Feng",
                "org": "Key Laboratory of Fruits and Vegetables Processing"
            },
            {
                "name": "Junjie Yi",
                "org": "Research Center of Fruits and Vegetables Processing Engineering"
            },
            {
                "name": "Cheng Hua",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Fang Chen",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaojun Liao",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Zhengfu Wang",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaosong Hu",
                "org": "College of Food Science and Nutritional Engineering"
            }
        ],
        "title": "High hydrostatic pressure inactivation of total aerobic bacteria, lactic acid bacteria, yeasts in sour Chinese cabbage",
        "keywords": [
            "High hydrostatic pressure",
            "Inactivation",
            "Lactic acid bacteria",
            "Sour Chinese cabbage",
            "Total aerobic bacteria",
            "Yeasts"
        ],
        "venue": "International Journal of Food Microbiology",
        "year": 2010,
        "id": "fQ8y0GMg"
    },
    "mzKhKjXy": {
        "authors": [
            {
                "name": "Sichao Yang",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Hui Zhang",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Junhan Wang",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Fang Chen",
                "org": "College of Food Science and Nutritional Engineering"
            }
        ],
        "title": "Quantification of acrylamide in foods by gas chromatography-mass spectrometry coupled with pro-column derivatization",
        "keywords": [
            "Acrylamide",
            "Foods",
            "Gas chromatography-mass spectrometry ( GC-MS )",
            "Pro-column derivatization"
        ],
        "venue": "Chinese Journal of Chromatography (Se Pu)",
        "year": 2011,
        "id": "mzKhKjXy"
    },
    "YOMWYh8k": {
        "authors": [
            {
                "name": "Yingjie Yang",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaojun Liao",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaosong Hu",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Yan Zhang",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Fang Chen",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Jihong Wu",
                "org": "College of Food Science and Nutritional Engineering"
            }
        ],
        "title": "The contribution of high pressure carbon dioxide in the inactivation kinetics and structural alteration of myrosinase",
        "keywords": [
            "High pressure carbon dioxide",
            "Inactivation kinetics",
            "Myrosinase",
            "Structural alteration"
        ],
        "venue": "International Journal of Food Science and Technology",
        "year": 2011,
        "id": "YOMWYh8k"
    },
    "Rd0Gvt5h": {
        "authors": [
            {
                "name": "Lei Li",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Tao Zhang",
                "org": "College of Animal Science and Technology"
            },
            {
                "name": "Zhijian Sun",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Fang Chen",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Xiaosong Hu",
                "org": "College of Food Science and Nutritional Engineering"
            }
        ],
        "title": "Survey of acrylamide contents in Pu-erh tea and study on its formation mechanism",
        "keywords": [
            "Acrylamide",
            "Formation mechanism",
            "Pu-erh tea",
            "Wet-stored fermentation"
        ],
        "venue": "Nongye Jixie Xuebao/Transactions of the Chinese Society of Agricultural Machinery",
        "year": 2012,
        "id": "Rd0Gvt5h"
    },
    "VMK0jsHU": {
        "authors": [
            {
                "name": "Lijin Zhang",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Fang Chen",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Shaowen Liu",
                "org": "College of Sciences"
            },
            {
                "name": "Biyu Chen",
                "org": "Department of Food Science"
            },
            {
                "name": "Canping Pan",
                "org": "College of Sciences"
            }
        ],
        "title": "Ionic liquid-based vortex-assisted dispersive liquid-liquid microextraction of organophosphorus pesticides in apple and pear",
        "keywords": [
            "Dispersive liquid-liquid microextraction",
            "High-performance liquid chromatography",
            "Ionic liquid",
            "Organophosphorus pesticides"
        ],
        "venue": "Journal of Separation Science",
        "year": 2012,
        "id": "VMK0jsHU"
    },
    "C3DjnQT8": {
        "authors": [
            {
                "name": "Yuan Li",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Ruijing Ma",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Zhenzhen Xu",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Junhan Wang",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Tong Chen",
                "org": "Division of Medical Oncology"
            },
            {
                "name": "Fang Chen",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Zhengfu Wang",
                "org": "College of Food Science and Nutritional Engineering"
            }
        ],
        "title": "Identification and quantification of anthocyanins in Kyoho grape juice-making pomace, Cabernet Sauvignon grape winemaking pomace and their fresh skin",
        "keywords": [
            "Anthocyanin composition",
            "Cabernet Sauvignon",
            "Grape pomace",
            "Kyoho"
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        "venue": "Journal of the Science of Food and Agriculture",
        "year": 2013,
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                "org": ""
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                "org": ""
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            {
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                "org": ""
            }
        ],
        "title": "The identification of degradation products and degradation pathway of malvidin-3-glucoside and malvidin-3,5-diglucoside under microwave treatment",
        "keywords": [
            "Anthocyanins",
            "Degradation",
            "Identification",
            "Malvidin-3,5-diglucoside",
            "Malvidin-3-glucoside",
            "Microwave"
        ],
        "venue": "Food Chemistry",
        "year": 2013,
        "id": "ac6rEQiH"
    },
    "AbkYjuLg": {
        "authors": [
            {
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                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Fei Wang",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Yuan Li",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Fang Chen",
                "org": "College of Food Science and Nutritional Engineering"
            }
        ],
        "title": "Purification of anthocyanins from grape skin by integrated membrane process and column chromatography",
        "keywords": [
            "Anthocyanins",
            "Integrated membrane process",
            "Reverse osmosis",
            "Ultrafiltration"
        ],
        "venue": "Zhejiang Daxue Xuebao (Gongxue Ban)/Journal of Zhejiang University (Engineering Science)",
        "year": 2013,
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    "S7jzy5yI": {
        "authors": [
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                "org": ""
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            {
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                "org": ""
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        ],
        "title": "Protection of cyanidin-3-glucoside against oxidative stress induced by acrylamide in human MDA-MB-231 cells",
        "keywords": [
            "Acrylamide",
            "Cyanidin-3-glucoside",
            "Cytochrome P450 2E1",
            "Cytotoxicity",
            "Glutathione",
            "Intervention"
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    "Puhmwcna": {
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                "org": "College of Food Science and Nutritional Engineering, Key Laboratory of Fruits and Vegetables Processing, China Agricultural University"
            },
            {
                "name": "Yinghua Luo",
                "org": "Department of Nutrition and Food Science, University of Maryland"
            },
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                "org": "College of Food Science and Nutritional Engineering, Key Laboratory of Fruits and Vegetables Processing, China Agricultural University"
            },
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                "org": "College of Food Science and Nutritional Engineering, Key Laboratory of Fruits and Vegetables Processing, China Agricultural University"
            },
            {
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                "org": "College of Food Science and Nutritional Engineering, Key Laboratory of Fruits and Vegetables Processing, China Agricultural University"
            },
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                "org": "College of Food Science and Nutritional Engineering, Key Laboratory of Fruits and Vegetables Processing, China Agricultural University"
            },
            {
                "name": "Fang Chen",
                "org": "College of Food Science and Nutritional Engineering, Key Laboratory of Fruits and Vegetables Processing, China Agricultural University"
            }
        ],
        "title": "Simultaneous determination of free amino acids in Pu-erh tea and their changes during fermentation",
        "keywords": [
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            "Determination",
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                "org": "College of Food Science and Nutritional Engineering, Ministry of Education"
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            {
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                "org": "College of Food Science and Nutritional Engineering, Ministry of Education"
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                "org": "College of Food Science and Nutritional Engineering, Ministry of Education"
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            {
                "name": "Xiaosong Hu",
                "org": "College of Food Science and Nutritional Engineering, Ministry of Education"
            }
        ],
        "title": "The degradation of chlorpyrifos and diazinon in aqueous solution by ultrasonic irradiation: Effect of parameters and degradation pathway",
        "keywords": [
            "Chlorpyrifos",
            "Degradation products",
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    "qp0nizpg": {
        "authors": [
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                "org": "College of Food Science and Nutritional Engineering, National Engineering Research Centre for Fruits and Vegetables Processing, Key Laboratory of Fruits and Vegetables Processing, Ministry of Agriculture, Engineering Research Centre for Fruits and Vegetables Processing, Ministry of Education, China Agricultural University"
            },
            {
                "name": "Pengpu Wang",
                "org": "College of Food Science and Nutritional Engineering, National Engineering Research Centre for Fruits and Vegetables Processing, Key Laboratory of Fruits and Vegetables Processing, Ministry of Agriculture, Engineering Research Centre for Fruits and Vegetables Processing, Ministry of Education, China Agricultural University"
            },
            {
                "name": "Yuchen Zhu",
                "org": "College of Food Science and Nutritional Engineering, National Engineering Research Centre for Fruits and Vegetables Processing, Key Laboratory of Fruits and Vegetables Processing, Ministry of Agriculture, Engineering Research Centre for Fruits and Vegetables Processing, Ministry of Education, China Agricultural University"
            },
            {
                "name": "Xin Liu",
                "org": "College of Food Science and Nutritional Engineering, National Engineering Research Centre for Fruits and Vegetables Processing, Key Laboratory of Fruits and Vegetables Processing, Ministry of Agriculture, Engineering Research Centre for Fruits and Vegetables Processing, Ministry of Education, China Agricultural University"
            },
            {
                "name": "Xiaosong Hu",
                "org": "College of Food Science and Nutritional Engineering, National Engineering Research Centre for Fruits and Vegetables Processing, Key Laboratory of Fruits and Vegetables Processing, Ministry of Agriculture, Engineering Research Centre for Fruits and Vegetables Processing, Ministry of Education, China Agricultural University"
            },
            {
                "name": "Fang Chen",
                "org": "College of Food Science and Nutritional Engineering, National Engineering Research Centre for Fruits and Vegetables Processing, Key Laboratory of Fruits and Vegetables Processing, Ministry of Agriculture, Engineering Research Centre for Fruits and Vegetables Processing, Ministry of Education, China Agricultural University"
            }
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                "org": "College of Life Science"
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                "org": "College of Life Science"
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                "org": "College of Life Science"
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                "name": "Fang Chen",
                "org": "College of Life Science"
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        "title": "Determination of momordicoside A in bitter melon by high-performance liquid chromatography after solid-phase extraction",
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            {
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                "org": ""
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        ],
        "title": "Molecular cloning and characterization of rice pollen profilin",
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            "Cloning and expression",
            "Pollen",
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        ],
        "title": "RAPD markers in diversity detection and variety identification of Tibetan hulless barley",
        "keywords": [
            "\u03b2-glucan",
            "Cluster analysis",
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            "RAPD",
            "Tibetan hulless barley"
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    },
    "exjixLlm": {
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                "org": "College of Life Science"
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            {
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                "org": "College of Life Science"
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                "org": "College of Life Science"
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                "org": "College of Life Science"
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                "org": "College of Life Science"
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                "org": "College of Life Science"
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                "name": "Fang Chen",
                "org": "College of Life Science"
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        "title": "Identification of bulb from Fritillaria cirrhosa by PCR with specific primers",
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    "7XtXh1r5": {
        "authors": [
            {
                "name": "Yuhong Zeng",
                "org": "College of Life Science"
            },
            {
                "name": "Fang Yan",
                "org": "College of Life Science"
            },
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                "name": "Lin Tang",
                "org": "College of Life Science"
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            {
                "name": "Fang Chen",
                "org": "College of Life Science"
            }
        ],
        "title": "Increased crocin production and induction frequency of stigma-like-structure from floral organs of Crocus sativus by precursor feeding",
        "keywords": [
            "Crocin",
            "Crocus sativus L.",
            "HPLC",
            "Sodium acetate",
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    "TF3381NV": {
        "authors": [
            {
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                "org": "College of Life Science"
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            {
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                "org": "College of Life Science"
            },
            {
                "name": "Lin Tang",
                "org": "College of Life Science"
            },
            {
                "name": "Fang Chen",
                "org": "College of Life Science"
            }
        ],
        "title": "Antitumor effects of curcin from seeds of Jatropha curcas",
        "keywords": [
            "Antineoplastic agents",
            "Curcin",
            "Hela cells",
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                "org": "College of Life Science"
            },
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                "org": "College of Life Science"
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                "org": "Shaanxi Key Lab. of Bio-resources"
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                "org": "Stt. Key Lab. of Genetic Engineering"
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            {
                "name": "Fang Chen",
                "org": "College of Life Science"
            }
        ],
        "title": "Cloning and characterization of a curcin gene encoding a ribosome inactivating protein from Jatropha curcas",
        "keywords": [
            "Curcin",
            "Genomic cloning",
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            "Jatropha curcas",
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            {
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                "org": "College of Life Science"
            },
            {
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                "org": "College of Life Science"
            },
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                "org": "College of Life Science"
            },
            {
                "name": "Jianchuan Mo",
                "org": "College of Bioinformation"
            },
            {
                "name": "Jinku Bao",
                "org": "College of Life Science"
            },
            {
                "name": "Chen Miao",
                "org": "College of Life Science"
            },
            {
                "name": "Jie Bai",
                "org": "College of Life Science"
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                "name": "Fang Yan",
                "org": "College of Life Science"
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            {
                "name": "Fang Chen",
                "org": "College of Life Science"
            }
        ],
        "title": "An optimized gossypol high-performance liquid chromatography assay and its application in evaluation of different gland genotypes of cotton",
        "keywords": [
            "Cotton (Gossypium)",
            "Gossypol",
            "High-performance liquid chromatography (HPLC)",
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        "authors": [
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                "org": "College of Life Science"
            },
            {
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                "org": "College of Life Science"
            },
            {
                "name": "Fang Yan",
                "org": "College of Life Science"
            },
            {
                "name": "Fang Chen",
                "org": "College of Life Science"
            },
            {
                "name": "Xinshen Zhang",
                "org": "Coll. of Food and Light Engineering"
            },
            {
                "name": "Minhua Liu",
                "org": "Coll. of Food and Light Engineering"
            },
            {
                "name": "Weiguo Liu",
                "org": "Coll. of Food and Light Engineering"
            }
        ],
        "title": "Semi-preparative isolation of crocins from saffron (Crocus sativus L.)",
        "keywords": [
            "Column liquid chromatography",
            "Crocins",
            "Saffron",
            "Styrene-DVB mixed with starch"
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                "org": ""
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            {
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                "org": ""
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            {
                "name": "Fang Chen",
                "org": ""
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        ],
        "title": "Determination of crocin-1 in rabbit plasma and the pharmacokinetics by RP-HPLC",
        "keywords": [
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            {
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                "org": ""
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        ],
        "title": "Molecular cloning regulation of chilling-repressed gene atpA in Elumus sibiricus",
        "keywords": [
            "atpA gene",
            "Chilling stress",
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        "authors": [
            {
                "name": "Ya-Li Ge",
                "org": "College of Life Science"
            },
            {
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                "org": "College of Life Science"
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                "org": "College of Life Science"
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                "name": "Li-Li Dong",
                "org": "College of Life Science"
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                "org": "College of Life Science"
            },
            {
                "name": "Xiao-Ping Xu",
                "org": "College of Life Science"
            }
        ],
        "title": "Effects of food concentration on the duration of reproductive period and the formation of mictic female in different strains of freshwater rotifer Brachionus calyciflorus",
        "keywords": [
            "Brachionus calyciflorus",
            "Duration of reproductive period",
            "Food concentration",
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        "year": 2005,
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    "z38nlFD3": {
        "authors": [
            {
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                "org": "College of Life Science"
            },
            {
                "name": "Jin-Zhi Liu",
                "org": "College of Life Science"
            },
            {
                "name": "Chuan-Fang Wu",
                "org": "College of Life Science"
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                "name": "Jian Li",
                "org": "College of Life Science"
            },
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                "name": "Lei Dai",
                "org": "College of Life Science"
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                "org": "Department of Molecular Biotechnology"
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                "org": "Rega Institute for Medical Research"
            },
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                "org": "Rega Institute for Medical Research"
            },
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                "org": "College of Life Science"
            },
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                "org": "College of Life Science"
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        ],
        "title": "Anti-HIV I/II activity and molecular cloning of a novel mannose/sialic acid-binding lectin from rhizome of Polygonatum cyrtonema Hua",
        "keywords": [
            "3\u2032/5\u2032-rapid amplification of cDNA ends (RACE)",
            "Anti-human immunodeficiency virus (HIV) I/II",
            "Docking",
            "Mannose-binding lectin",
            "Molecular cloning",
            "Molecular modeling",
            "Polygonatum cyrtonema HUA",
            "Sequence alignment"
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        "year": 2006,
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        "authors": [
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                "org": "College of Life Science"
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            {
                "name": "Shuwen Zhang",
                "org": "College of Life Science"
            },
            {
                "name": "Lin Yang",
                "org": "College of Life Science"
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            {
                "name": "Ying Xu",
                "org": "College of Life Science"
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            {
                "name": "Lin Tang",
                "org": "College of Life Science"
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            {
                "name": "Shenghua Wang",
                "org": "College of Life Science"
            },
            {
                "name": "Huimin Tan",
                "org": "College of Life Science"
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            {
                "name": "Fang Chen",
                "org": "College of Life Science"
            }
        ],
        "title": "Callus induction from Jatropha curcas endosperm and elimination of microbial contamination in culture",
        "keywords": [
            "Callus induction",
            "Disinfectant",
            "Endosperm",
            "Jatropha curcas",
            "Sterilization time"
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        "venue": "Chinese Journal of Applied and Environmental Biology",
        "year": 2006,
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    "ro1vzZHZ": {
        "authors": [
            {
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                "org": "College of Life Science"
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            {
                "name": "Jian Che",
                "org": "College of Life Science"
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            {
                "name": "Yan-Jun Liu",
                "org": "College of Life Science"
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                "name": "Wei He",
                "org": "College of Life Science"
            },
            {
                "name": "Fang Chen",
                "org": "College of Life Science"
            }
        ],
        "title": "Molecular identity of Crocus sativus and its misused substitutes by ITS sequence",
        "keywords": [
            "Chinese traditional medicine identification",
            "Crocus sativus",
            "ITS sequence"
        ],
        "venue": "Zhongguo Zhongyao Zazhi",
        "year": 2007,
        "id": "ro1vzZHZ"
    },
    "bRLgfWT4": {
        "authors": [
            {
                "name": "Bei Niu",
                "org": "College of Life Science"
            },
            {
                "name": "Huaxun Ye",
                "org": "College of Life Science"
            },
            {
                "name": "Ying Xu",
                "org": "College of Life Science"
            },
            {
                "name": "Shenghua Wang",
                "org": "College of Life Science"
            },
            {
                "name": "Peng Chen",
                "org": "College of Life Science"
            },
            {
                "name": "Shuming Peng",
                "org": "College of Life Science"
            },
            {
                "name": "Yangchao Ou",
                "org": "College of Life Science"
            },
            {
                "name": "Lin Tang",
                "org": "College of Life Science"
            },
            {
                "name": "Fang Chen",
                "org": "College of Life Science"
            }
        ],
        "title": "Cloning and characterization of a novel \u039412-fatty acid desaturase gene from the tree Sapium sebiferum",
        "keywords": [
            "\u039412-fatty acid desaturase",
            "Cloning",
            "Saccharomyces cerevisiae",
            "Sapium sebiferum"
        ],
        "venue": "Biotechnology Letters",
        "year": 2007,
        "id": "bRLgfWT4"
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        "authors": [
            {
                "name": "Jun Chun",
                "org": "College of Life Science"
            },
            {
                "name": "Yan-Feng Zheng",
                "org": "College of Life Science"
            },
            {
                "name": "Sheng-Hua Wang",
                "org": "College of Life Science"
            },
            {
                "name": "Fang Chen",
                "org": "College of Life Science"
            }
        ],
        "title": "A RNA isolation method suitable for a wide range of materials",
        "keywords": [
            "Ethylene glycol monobutyl ether",
            "Macaloid",
            "RNA extraction",
            "Small RNAs"
        ],
        "venue": "Progress in Biochemistry and Biophysics",
        "year": 2008,
        "id": "aLRPeNWM"
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        "authors": [
            {
                "name": "Bei Niu",
                "org": "College of Life Science"
            },
            {
                "name": "Liang Guo",
                "org": "College of Life Science"
            },
            {
                "name": "Mingming Zhao",
                "org": "College of Life Science"
            },
            {
                "name": "Tong Luo",
                "org": "College of Life Science"
            },
            {
                "name": "Rong Zhang",
                "org": "College of Life Science"
            },
            {
                "name": "Fuli Zhang",
                "org": "College of Life Science"
            },
            {
                "name": "Pei Hou",
                "org": "College of Life Science"
            },
            {
                "name": "Ying Zhang",
                "org": "College of Life Science"
            },
            {
                "name": "Ying Xu",
                "org": "College of Life Science"
            },
            {
                "name": "Shenghua Wang",
                "org": "College of Life Science"
            },
            {
                "name": "Fang Chen",
                "org": "College of Life Science"
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        "title": "Molecular Cloning, Characterization, and Expression of an \u03c9-3 Fatty Acid Desaturase Gene from Sapium sebiferum",
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            "\u03c9-3 fatty acid desaturase gene",
            "cloning",
            "Saccharomyces cerevisiae",
            "Sapium sebiferum (L.) Roxb"
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        "venue": "Journal of Bioscience and Bioengineering",
        "year": 2008,
        "id": "HDrUrBZk"
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        "authors": [
            {
                "name": "Mengjun Luo",
                "org": "College of Life Science"
            },
            {
                "name": "Fang Chen",
                "org": "College of Life Science"
            },
            {
                "name": "Fang Yan",
                "org": "College of Life Science"
            },
            {
                "name": "Weixin Liu",
                "org": "Family Planning Technology Institute of Chengdu"
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        ],
        "title": "Study on expression of curcin gene cloned from Jatropha curcas in Escherichia coli",
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            "Expression vector",
            "Induced expression",
            "Jatropha curcas",
            "RIPs"
        ],
        "venue": "Zhongguo Zhongyao Zazhi",
        "year": 2009,
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        "authors": [
            {
                "name": "Xue Tian",
                "org": "College of Life Science"
            },
            {
                "name": "Bin Zhou",
                "org": "College of Life Science"
            },
            {
                "name": "Xin Li",
                "org": "College of Life Science"
            },
            {
                "name": "Fang Chen",
                "org": "College of Life Science"
            },
            {
                "name": "Jianfeng Gao",
                "org": "College of Life Science"
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        "title": "Synthesis of biodiesel from cottonseed oil and dimethyl carbonate catalyzed by immobilized lipase",
        "keywords": [
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            "Cottonseed oil",
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            "Immobilized lipase",
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            "Transesterification"
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        "venue": "Shiyou Huagong/Petrochemical Technology",
        "year": 2009,
        "id": "hvLxt04i"
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            {
                "name": "Zeng-Bin Luo",
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            {
                "name": "Guo-Qing Zhuang",
                "org": "Sichuan Academy of Forestry"
            },
            {
                "name": "Dan-Wei Ma",
                "org": "College of Life Science"
            },
            {
                "name": "Fang Chen",
                "org": "College of Life Science"
            }
        ],
        "title": "Genetic diversity of Pogonatherum paniceum (Lam.) Hack in Southwest China revealed by ISSR",
        "keywords": [
            "Genetic diversity",
            "ISSR",
            "P. paniceum (Lam.) Hack",
            "Southwest China"
        ],
        "venue": "African Journal of Biotechnology",
        "year": 2010,
        "id": "ieCMd03W"
    },
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        "authors": [
            {
                "name": "Jun Wu",
                "org": "College of Life Science"
            },
            {
                "name": "Yiran Guo",
                "org": "College of Life Science"
            },
            {
                "name": "Yuan Liu",
                "org": "College of Life Science"
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            {
                "name": "Fang Chen",
                "org": "College of Life Science"
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        "title": "Rapid determination of oil content in seed of Jatropha curcas by NMR",
        "keywords": [
            "Jatropha Curcas",
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            "Oil content",
            "Seed",
            "Soxhlet extraction"
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                "name": "Li Sun",
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            {
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            {
                "name": "Shanglong Kou",
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            {
                "name": "Shenghua Wang",
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            {
                "name": "Yunyi Yao",
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            {
                "name": "Tong Peng",
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            },
            {
                "name": "Ying Xu",
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            {
                "name": "Lin Tang",
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            {
                "name": "Fang Chen",
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        "title": "Cloning and characterization of a cDNA encoding type 1 diacylglycerol acyltransferase from sunflower (Helianthus annuus L.)",
        "keywords": [
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            "Helianthus annuus L.",
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        "id": "14z8uTEE"
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                "name": "Lei Lei",
                "org": "College of Life Science"
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            {
                "name": "Zheren Fan",
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            {
                "name": "Lin Tang",
                "org": "College of Life Science"
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            {
                "name": "Fang Chen",
                "org": "College of Life Science"
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        "title": "Molecular cloning and identification of tissue-specific expression of ent-kaurene oxidase gene in momordica charantia",
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        "title": "Genetic diversity of wheat-rye 1BL.1RS translocation lines derived from different wheat and rye sources",
        "keywords": [
            "Agronomic traits",
            "End-use quality",
            "Resistance",
            "Secale cereale",
            "Triticum aestivum"
        ],
        "venue": "Euphytica",
        "year": 2012,
        "id": "NPh9knoW"
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        "authors": [
            {
                "name": "Zhanguo Wang",
                "org": "College of Life Science"
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            {
                "name": "Huiling Hu",
                "org": "School of Chinese Pharmacy"
            },
            {
                "name": "Fang Chen",
                "org": "College of Life Science"
            },
            {
                "name": "Ke Lan",
                "org": "Key Laboratory of Drug Targeting and Drug Delivery System of the Education Ministry"
            },
            {
                "name": "Anqi Wang",
                "org": "Key Laboratory of Drug Targeting and Drug Delivery System of the Education Ministry"
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        ],
        "title": "Reduced system exposures of total rhein and baicalin after combinatory oral administration of rhein, baicalin and berberine to beagle dogs and rats",
        "keywords": [
            "\u03b2-Glucuronidase/sulfatase",
            "Baicalin",
            "Berberine",
            "Enterohepatic circulation",
            "Rhein"
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        "venue": "Journal of Ethnopharmacology",
        "year": 2013,
        "id": "IpVRHizE"
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    "ZnhN2MDN": {
        "authors": [
            {
                "name": "Chen Miao",
                "org": "College of Life Sciences"
            },
            {
                "name": "Xiao-Ping Gou",
                "org": "College of Life Sciences"
            },
            {
                "name": "Li-Qiong Lan",
                "org": "College of Life Sciences"
            },
            {
                "name": "Jin-Ku Bao",
                "org": "College of Life Sciences"
            },
            {
                "name": "Ying Xu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Sheng-Hua Wang",
                "org": "College of Life Sciences"
            },
            {
                "name": "Fang Chen",
                "org": "College of Life Sciences"
            }
        ],
        "title": "Molecular cloning and expression of RSSG58 gene in rice sperm cells",
        "keywords": [
            "Expression",
            "Molecular cloning",
            "Rice",
            "RSSG58 gene",
            "Sperm cell"
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        "venue": "Acta Botanica Sinica",
        "year": 2003,
        "id": "ZnhN2MDN"
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        "authors": [
            {
                "name": "Yu Bai",
                "org": "College of Life Sciences"
            },
            {
                "name": "Ying Xu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Lin Tang",
                "org": "College of Life Sciences"
            },
            {
                "name": "Fang Yan",
                "org": "College of Life Sciences"
            },
            {
                "name": "Xiao-Ping Guo",
                "org": "College of Life Sciences"
            },
            {
                "name": "Fang Chen",
                "org": "College of Life Sciences"
            }
        ],
        "title": "Molecular cloning and preliminary study of a gene differentially expressed in rice sperm cells",
        "keywords": [
            "Cloning",
            "Expression",
            "Rice",
            "Sperm cell"
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        "venue": "Acta Botanica Sinica",
        "year": 2003,
        "id": "uGTrffLl"
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    "q6WWRe4a": {
        "authors": [
            {
                "name": "Juan Lin",
                "org": "College of Life Sciences"
            },
            {
                "name": "Yu Chen",
                "org": "College of Life Sciences"
            },
            {
                "name": "Ying Xu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Fang Yan",
                "org": "College of Life Sciences"
            },
            {
                "name": "Lin Tang",
                "org": "College of Life Sciences"
            },
            {
                "name": "Fang Chen",
                "org": "College of Life Sciences"
            }
        ],
        "title": "Cloning and expression of curcin, a ribosome-inactivating protein from the seeds of Jatropha curcas",
        "keywords": [
            "Cloning",
            "Curcin",
            "In Escherichia coil expression",
            "Jatropha curcas",
            "RNA N-glycosidase"
        ],
        "venue": "Acta Botanica Sinica",
        "year": 2003,
        "id": "q6WWRe4a"
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    "fy7S15Nw": {
        "authors": [
            {
                "name": "Chuan-Fang Wu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Jie An",
                "org": "College of Life Sciences"
            },
            {
                "name": "Xiao-Jia He",
                "org": "College of Life Sciences"
            },
            {
                "name": "Jie Deng",
                "org": "College of Life Sciences"
            },
            {
                "name": "Zhi-Xia Hong",
                "org": "College of Life Sciences"
            },
            {
                "name": "Chao Liu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Hong-Zhou Lu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Yi-Jin Li",
                "org": "College of Life Sciences"
            },
            {
                "name": "Chen-Ji Wang",
                "org": "College of Life Sciences"
            },
            {
                "name": "Fang Chen",
                "org": "College of Life Sciences"
            },
            {
                "name": "Jin-Ku Bao",
                "org": "College of Life Sciences"
            }
        ],
        "title": "Molecular cloning of a novel mannose-binding lectin gene from bulbs of Amaryllis vittata (Amaryllidaceae)",
        "keywords": [
            "3' and 5' RACE",
            "Amaryllis vittata agglutinin (AVA)",
            "Degenerate primers",
            "Homology alignment",
            "Monocot mannose-binding lectin"
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        "venue": "Acta Botanica Sinica",
        "year": 2004,
        "id": "fy7S15Nw"
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    "7NlEwG5g": {
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            {
                "name": "Shun Gao",
                "org": ""
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            {
                "name": "Jie An",
                "org": ""
            },
            {
                "name": "Chuan-Fang Wu",
                "org": ""
            },
            {
                "name": "Ying Gu",
                "org": ""
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            {
                "name": "Fang Chen",
                "org": ""
            },
            {
                "name": "Yuan Yu",
                "org": ""
            },
            {
                "name": "Qia-Qing Wu",
                "org": ""
            },
            {
                "name": "Jin-Ku Bao",
                "org": ""
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        ],
        "title": "Effect of amino acid residue and oligosaccharide chain chemical modifications on spectral and hemagglutinating activity of Millettia dielsiana Harms. ex Diels. lectin",
        "keywords": [
            "Chemical modification",
            "Circular dichroism",
            "Fluorescence quenching",
            "Hemagglutinating activity",
            "Millettia dielsiana Harms. ex Diels. lectin (MDL)"
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        "venue": "Acta Biochimica et Biophysica Sinica",
        "year": 2005,
        "id": "7NlEwG5g"
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    "6arqsVlQ": {
        "authors": [
            {
                "name": "Junping Deng",
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            {
                "name": "Shuangchun Yan",
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            },
            {
                "name": "Pei Hou",
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            {
                "name": "Ying Xu",
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            },
            {
                "name": "Shenghua Wang",
                "org": ""
            },
            {
                "name": "Lin Tang",
                "org": ""
            },
            {
                "name": "Fang Yan",
                "org": ""
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            {
                "name": "Fang Chen",
                "org": ""
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        ],
        "title": "Effects of different antibiotics at various concentrations on culture of Jatropha curcas",
        "keywords": [
            "Analysis of variance (ANOVA)",
            "Antibiotic",
            "Explant growth",
            "Jatropha curcas",
            "Tissue culture"
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        "venue": "Chinese Journal of Applied and Environmental Biology",
        "year": 2005,
        "id": "6arqsVlQ"
    },
    "ZZntu7H4": {
        "authors": [
            {
                "name": "Liqing Chang",
                "org": "College of Life Sciences"
            },
            {
                "name": "Chuanfang Wu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Hongzhou L\u00fc",
                "org": "College of Life Sciences"
            },
            {
                "name": "Chao Liu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Ying Gu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Fang Chen",
                "org": "College of Life Sciences"
            },
            {
                "name": "Qiaqing Wu",
                "org": "Chengdu Institute of Biology"
            },
            {
                "name": "Jinku Bao",
                "org": "College of Life Sciences"
            }
        ],
        "title": "Purification and characterization of agglutinin from bulbs of Lycoris radiata (Amaryllidaceae)",
        "keywords": [
            "Antiviral activity",
            "Hemagglutinating activity",
            "Lycoris radiata agglutinin (LRA)",
            "Mitogenic activity",
            "Purification"
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        "venue": "Chinese Journal of Applied and Environmental Biology",
        "year": 2005,
        "id": "ZZntu7H4"
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    "rg6wRGz2": {
        "authors": [
            {
                "name": "Xiaolin Zhang",
                "org": "College of Life Sciences"
            },
            {
                "name": "Shenghua Wang",
                "org": "College of Life Sciences"
            },
            {
                "name": "Lin Tang",
                "org": "College of Life Sciences"
            },
            {
                "name": "Ying Xu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Yongjiong Jia",
                "org": "College of Life Sciences"
            },
            {
                "name": "Fang Chen",
                "org": "College of Life Sciences"
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        "title": "Cloning and function identifiction of rice sperm-predominant expressed gene RSSG58\u2032s promoter",
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            "JP58",
            "pBI121",
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        "year": 2005,
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        "authors": [
            {
                "name": "Fang Chen",
                "org": "College of Life Sciences"
            },
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                "name": "Yi-Long Xi",
                "org": "College of Life Sciences"
            },
            {
                "name": "Ya-Li Ge",
                "org": "College of Life Sciences"
            },
            {
                "name": "Xiao-Ping Xu",
                "org": "College of Life Sciences"
            }
        ],
        "title": "Life history traits of mictic females in two strains of Brachionus calyciflorus (Rotifera)",
        "keywords": [
            ""
        ],
        "venue": "Journal of Freshwater Ecology",
        "year": 2005,
        "id": "Ok68Q4he"
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    "fnUzSNZd": {
        "authors": [
            {
                "name": "Yi-Long Xi",
                "org": "College of Life Sciences"
            },
            {
                "name": "Ya-Li Ge",
                "org": "College of Life Sciences"
            },
            {
                "name": "Fang Chen",
                "org": "College of Life Sciences"
            },
            {
                "name": "Xin-Li Wen",
                "org": "College of Life Sciences"
            },
            {
                "name": "Li-Li Dong",
                "org": "College of Life Sciences"
            }
        ],
        "title": "Life history characteristics of three strains of Brachionus calyciflorus (Rotifera) at different temperatures",
        "keywords": [
            ""
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        "venue": "Journal of Freshwater Ecology",
        "year": 2005,
        "id": "fnUzSNZd"
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    "lS1pAJSG": {
        "authors": [
            {
                "name": "Chuan-Fang Wu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Jian Li",
                "org": "College of Life Sciences"
            },
            {
                "name": "Jie An",
                "org": "College of Life Sciences"
            },
            {
                "name": "Li-Qing Chang",
                "org": "College of Life Sciences"
            },
            {
                "name": "Fang Chen",
                "org": "College of Life Sciences"
            },
            {
                "name": "Jin-Ku Bao",
                "org": "College of Life Sciences"
            }
        ],
        "title": "Purification, biological activities, and molecular cloning of a novel mannose-binding lectin from bulbs of Zephyranthes candida Herb (Amaryllidaceae)",
        "keywords": [
            "Agglutinating activity",
            "Insecticidal activity",
            "Molecular clone",
            "Sequence analysis",
            "Zephyranthes candida agglutinin"
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        "venue": "Journal of Integrative Plant Biology",
        "year": 2006,
        "id": "lS1pAJSG"
    },
    "7GYkxzXN": {
        "authors": [
            {
                "name": "Meng-Jun Luo",
                "org": "College of Life Sciences"
            },
            {
                "name": "Xin-Yu Yang",
                "org": "College of Life Sciences"
            },
            {
                "name": "Wei-Xin Liu",
                "org": "Chengdu Institute for Family Planning"
            },
            {
                "name": "X.U. Ying",
                "org": "College of Life Sciences"
            },
            {
                "name": "Ping Huang",
                "org": "Chengdu Institute for Family Planning"
            },
            {
                "name": "Fang Yan",
                "org": "College of Life Sciences"
            },
            {
                "name": "Fang Chen",
                "org": "College of Life Sciences"
            }
        ],
        "title": "Expression, purification and anti-tumor activity of curcin",
        "keywords": [
            "Anti-tumor activity",
            "Curcin",
            "Expression",
            "Purification",
            "Recombinant protein"
        ],
        "venue": "Acta Biochimica et Biophysica Sinica",
        "year": 2006,
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    },
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        "authors": [
            {
                "name": "Hua Li",
                "org": ""
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            {
                "name": "Li Chen",
                "org": ""
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            {
                "name": "Lin Tang",
                "org": ""
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            {
                "name": "Fang Chen",
                "org": ""
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        ],
        "title": "Physicochemical characteristics and fatty-acid composition of seed oil of Jatropha curcas from Southwest China",
        "keywords": [
            "Biofuel",
            "Fatty acid",
            "Jatropha curcas L.",
            "Seed oil"
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        "venue": "Chinese Journal of Applied and Environmental Biology",
        "year": 2006,
        "id": "T3HgdGwD"
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        "authors": [
            {
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                "org": "College of Life Sciences"
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            {
                "name": "Shenghua Wang",
                "org": "College of Life Sciences"
            },
            {
                "name": "Tong Luo",
                "org": "College of Life Sciences"
            },
            {
                "name": "Wenguo Wang",
                "org": "College of Life Sciences"
            },
            {
                "name": "Guoqing Zhuang",
                "org": "College of Life Sciences"
            },
            {
                "name": "Fang Chen",
                "org": "College of Life Sciences"
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        ],
        "title": "Comparitive study on genetic diversity of rock plant Pogonatherum paniceum using ISSR and AFLP markers",
        "keywords": [
            "AFLP",
            "Genetic diversity",
            "ISSR",
            "Pogonatherum paniceum"
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        "venue": "Chinese Journal of Applied and Environmental Biology",
        "year": 2006,
        "id": "SUGVQDe7"
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        "authors": [
            {
                "name": "Zhang-He Chen",
                "org": "College of Life Sciences"
            },
            {
                "name": "Fang Chen",
                "org": "College of Life Sciences"
            },
            {
                "name": "Xu-Cheng Liu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Xiu-Yun Cheng",
                "org": "College of Life Sciences"
            },
            {
                "name": "Yu-Bin Wang",
                "org": "College of Life Sciences"
            },
            {
                "name": "Xian-Ye Zhou",
                "org": "College of Life Sciences"
            }
        ],
        "title": "A new method for root biomass measurement in subsurface flow gravel-bed constructed wetlands",
        "keywords": [
            "Biomass",
            "Distribution",
            "Mesh cylinder",
            "New method",
            "Root",
            "Subsurface flow constructed wetland"
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        "venue": "Shengtai Xuebao/ Acta Ecologica Sinica",
        "year": 2007,
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    },
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        "authors": [
            {
                "name": "Jiwei Liu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Xiaochao Xu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Jinzhi Liu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Jan Balzarini",
                "org": "Rega Institute for Medical Research"
            },
            {
                "name": "Yongtin Luo",
                "org": "College of Life Sciences"
            },
            {
                "name": "Yang Kong",
                "org": "College of Life Sciences"
            },
            {
                "name": "Jian Li",
                "org": "College of Life Sciences"
            },
            {
                "name": "Fang Chen",
                "org": "College of Life Sciences"
            },
            {
                "name": "Els Van Damme",
                "org": "Department of Molecular Biotechnology"
            },
            {
                "name": "Jinku Bao",
                "org": "College of Life Sciences"
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        ],
        "title": "A novel tetrameric lectin from Lycoris aurea with four mannose binding sites per monomer",
        "keywords": [
            "Lycoris aurea agglutinin",
            "Mannose-binding lectin",
            "Molecular modeling and docking",
            "Sequence alignment"
        ],
        "venue": "Acta Biochimica Polonica",
        "year": 2007,
        "id": "Yz9JkMin"
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        "authors": [
            {
                "name": "Fang Chen",
                "org": "College of Life Sciences"
            },
            {
                "name": "Yijuan Du",
                "org": "College of Life Sciences"
            },
            {
                "name": "Zheng Zhang",
                "org": "College of Life Sciences"
            },
            {
                "name": "Gang Chen",
                "org": "College of Life Sciences"
            },
            {
                "name": "Min Zhang",
                "org": "College of Life Sciences"
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            {
                "name": "Hong-Bing Shu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Zhonghe Zhai",
                "org": "College of Life Sciences"
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            {
                "name": "Danying Chen",
                "org": "College of Life Sciences"
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        "title": "Syntenin negatively regulates TRAF6-mediated IL-1R/TLR4 signaling",
        "keywords": [
            "IL-1R",
            "NF-\u03baB",
            "Syntenin",
            "TLR4",
            "TRAF6"
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        "venue": "Cellular Signalling",
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        "authors": [
            {
                "name": "Fu-Li Zhang",
                "org": "College of Life Sciences"
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            {
                "name": "Bei Niu",
                "org": "College of Life Sciences"
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            {
                "name": "Ying-Chun Wang",
                "org": "College of Life Sciences"
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            {
                "name": "Fang Chen",
                "org": "College of Life Sciences"
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            {
                "name": "Sheng-Hua Wang",
                "org": "College of Life Sciences"
            },
            {
                "name": "Ying Xu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Lu-Ding Jiang",
                "org": "College of Life Sciences"
            },
            {
                "name": "Shun Gao",
                "org": "College of Life Sciences"
            },
            {
                "name": "Jun Wu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Lin Tang",
                "org": "College of Life Sciences"
            },
            {
                "name": "Yong-Jiong Jia",
                "org": "College of Life Sciences"
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        ],
        "title": "A novel betaine aldehyde dehydrogenase gene from Jatropha curcas, encoding an enzyme implicated in adaptation to environmental stress",
        "keywords": [
            "Betaine aldehyde dehydrogenase",
            "Environmental stress",
            "Expression pattern",
            "Glycinebetaine",
            "Jatropha curcas",
            "Molecular cloning"
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        "venue": "Plant Science",
        "year": 2008,
        "id": "16ra82Sk"
    },
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        "authors": [
            {
                "name": "Sha Lin",
                "org": "College of Life Sciences"
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            {
                "name": "Shaoyin Luo",
                "org": "College of Life Sciences"
            },
            {
                "name": "Ying Lin",
                "org": "College of Life Sciences"
            },
            {
                "name": "Zhitao Wang",
                "org": "College of Life Sciences"
            },
            {
                "name": "Bei Niu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Xiaobo Qin",
                "org": "College of Life Sciences"
            },
            {
                "name": "Yueqin Li",
                "org": "College of Life Sciences"
            },
            {
                "name": "Ying Xu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Fang Chen",
                "org": "College of Life Sciences"
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        ],
        "title": "A simple method for extracting total RNAs from endosperm of Jatropha curcas L.",
        "keywords": [
            "Endosperm",
            "Jatropha curcas L.",
            "Oilseed",
            "RNA isolation"
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        "venue": "Chinese Journal of Applied and Environmental Biology",
        "year": 2008,
        "id": "hQiot4eY"
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        "authors": [
            {
                "name": "Xiao-Bo Qin",
                "org": "College of Life Sciences"
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            {
                "name": "Cai-Xia Shao",
                "org": "College of Life Sciences"
            },
            {
                "name": "Ying Xu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Fang Chen",
                "org": "College of Life Sciences"
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        ],
        "title": "Analysis on the expression patterns of two ribosome inactivating proteins from Jatropha curcas L.",
        "keywords": [
            "Expression pattern",
            "Jatropha curcas",
            "Ribosome inactivating protein",
            "Stress"
        ],
        "venue": "Plant Physiology Communications",
        "year": 2008,
        "id": "QNuoNFgK"
    },
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        "authors": [
            {
                "name": "Qin Tian",
                "org": "College of Life Sciences"
            },
            {
                "name": "Wei Wang",
                "org": "College of Life Sciences"
            },
            {
                "name": "Chen Miao",
                "org": "College of Life Sciences"
            },
            {
                "name": "Hao Peng",
                "org": "College of Life Sciences"
            },
            {
                "name": "Bo Liu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Fangwei Leng",
                "org": "College of Life Sciences"
            },
            {
                "name": "Lei Dai",
                "org": "College of Life Sciences"
            },
            {
                "name": "Fang Chen",
                "org": "College of Life Sciences"
            },
            {
                "name": "Jinku Bao",
                "org": "College of Life Sciences"
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        ],
        "title": "Purification, characterization and molecular cloning of a novel mannose-binding lectin from rhizomes of Ophiopogon japonicus with antiviral and antifungal activities",
        "keywords": [
            "Antifungal activity",
            "Antiviral activity",
            "Molecular cloning and modeling",
            "Ophiopogon japonicus lectin",
            "Phylogenetic analysis"
        ],
        "venue": "Plant Science",
        "year": 2008,
        "id": "xgnL3DFB"
    },
    "PChd7LkB": {
        "authors": [
            {
                "name": "Xiaobo Qin",
                "org": "College of Life Sciences"
            },
            {
                "name": "Jinping Zhang",
                "org": "College of Life Sciences"
            },
            {
                "name": "Caixia Shao",
                "org": "College of Life Sciences"
            },
            {
                "name": "Sha Lin",
                "org": "College of Life Sciences"
            },
            {
                "name": "Luding Jiang",
                "org": "College of Life Sciences"
            },
            {
                "name": "Shuwen Zhang",
                "org": "College of Life Sciences"
            },
            {
                "name": "Ying Xu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Fang Chen",
                "org": "College of Life Sciences"
            }
        ],
        "title": "Isolation and characterization of a curcin promoter from jatropha curcas L. and its regulation of gene expression in transgenic tobacco plants",
        "keywords": [
            "Curcin",
            "Jatropha curcas L",
            "Promoter",
            "Ribosome-inactivating protein"
        ],
        "venue": "Plant Molecular Biology Reporter",
        "year": 2009,
        "id": "PChd7LkB"
    },
    "JD7JmDSU": {
        "authors": [
            {
                "name": "Fu-Li Zhang",
                "org": "College of Life Sciences"
            },
            {
                "name": "Bei Niu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Ying-Chun Wang",
                "org": "College of Life Sciences"
            },
            {
                "name": "Fang Chen",
                "org": "College of Life Sciences"
            },
            {
                "name": "Sheng-Hua Wang",
                "org": "College of Life Sciences"
            },
            {
                "name": "Ying Xu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Lu-Ding Jiang",
                "org": "College of Life Sciences"
            },
            {
                "name": "Shun Gao",
                "org": "College of Life Sciences"
            },
            {
                "name": "Jun Wu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Lin Tang",
                "org": "College of Life Sciences"
            },
            {
                "name": "Yong-Jiong Jia",
                "org": "College of Life Sciences"
            }
        ],
        "title": "Erratum to \"A novel betaine aldehyde dehydrogenase gene from Jatropha curcas, encoding an enzyme implicated in adaptation to environmental stress\" [Plant Sci. 174 (2008) 510-518] (DOI:10.1016/j.plantsci.2008.01.018)",
        "keywords": [
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        ],
        "venue": "Plant Science",
        "year": 2009,
        "id": "JD7JmDSU"
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    "bRXDqRuO": {
        "authors": [
            {
                "name": "Song-Hua Ye",
                "org": "College of Life Sciences"
            },
            {
                "name": "Sheng Chen",
                "org": "College of Life Sciences"
            },
            {
                "name": "Fan Zhang",
                "org": "College of Life Sciences"
            },
            {
                "name": "Wei Wang",
                "org": "College of Life Sciences"
            },
            {
                "name": "Qin Tian",
                "org": "College of Life Sciences"
            },
            {
                "name": "Jin-Zhi Liu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Fang Chen",
                "org": "College of Life Sciences"
            },
            {
                "name": "Jin-Ku Bao",
                "org": "College of Life Sciences"
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        ],
        "title": "Transgenic tobacco expressing Zephyranthes grandiflora agglutinin confers enhanced resistance to aphids",
        "keywords": [
            "Bioassay",
            "Insect resistance",
            "Tobacco aphid (Myzus nicotianae)",
            "Transgenic tobacco",
            "Zephyranthes grandiflora agglutinin"
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        "venue": "Applied Biochemistry and Biotechnology",
        "year": 2009,
        "id": "bRXDqRuO"
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        "authors": [
            {
                "name": "Jing Chen",
                "org": "College of Life Sciences"
            },
            {
                "name": "Bo Liu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Na Ji",
                "org": "College of Life Sciences"
            },
            {
                "name": "Jing Zhou",
                "org": "College of Life Sciences"
            },
            {
                "name": "He-jiao Bian",
                "org": "College of Life Sciences"
            },
            {
                "name": "Chun-yang Li",
                "org": "College of Life Sciences"
            },
            {
                "name": "Fang Chen",
                "org": "College of Life Sciences"
            },
            {
                "name": "Jin-ku Bao",
                "org": "College of Life Sciences"
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        ],
        "title": "A novel sialic acid-specific lectin from Phaseolus coccineus seeds with potent antineoplastic and antifungal activities",
        "keywords": [
            "Antifungal activity",
            "Apoptosis",
            "Caspase-dependent",
            "Phaseolus coccineus lectin",
            "Sialic acid specificity"
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        "venue": "Phytomedicine",
        "year": 2009,
        "id": "1NDcNUYT"
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        "authors": [
            {
                "name": "Hui Liang",
                "org": "College of Life Sciences"
            },
            {
                "name": "Tong Peng",
                "org": "College of Life Sciences"
            },
            {
                "name": "Fang Yan",
                "org": "College of Life Sciences"
            },
            {
                "name": "Lin Tang",
                "org": "College of Life Sciences"
            },
            {
                "name": "Fang Chen",
                "org": "College of Life Sciences"
            }
        ],
        "title": "Oil content in kernel and phorbol ester content in defatted kernel of Jatropha curcas from different origins",
        "keywords": [
            "High performance liquid chromatography",
            "Jatropha curcas L.",
            "Kernel",
            "Oil content",
            "Phorbol ester"
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        "venue": "Chinese Journal of Applied and Environmental Biology",
        "year": 2009,
        "id": "gFOIdVo5"
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        "authors": [
            {
                "name": "Bin Liu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Wenguo Wang",
                "org": "College of Life Sciences"
            },
            {
                "name": "Jihai Gao",
                "org": "College of Life Sciences"
            },
            {
                "name": "Fang Chen",
                "org": "College of Life Sciences"
            },
            {
                "name": "Shenghua Wang",
                "org": "College of Life Sciences"
            },
            {
                "name": "Ying Xu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Lin Tang",
                "org": "College of Life Sciences"
            },
            {
                "name": "Yongjiong Jia",
                "org": "College of Life Sciences"
            }
        ],
        "title": "Molecular cloning and characterization of a jasmonate biosynthetic pathway gene for allene oxide cyclase from Jatropha curcas",
        "keywords": [
            "Allene oxide cyclase",
            "Expression",
            "Jatropha curcas",
            "Molecular cloning",
            "Stresses"
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        "venue": "Acta Physiologiae Plantarum",
        "year": 2010,
        "id": "nXnYq6oy"
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        "authors": [
            {
                "name": "Bin Liu",
                "org": ""
            },
            {
                "name": "Lin Yao",
                "org": ""
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            {
                "name": "Wenguo Wang",
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            {
                "name": "Jihai Gao",
                "org": ""
            },
            {
                "name": "Fang Chen",
                "org": ""
            },
            {
                "name": "Shenghua Wang",
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            },
            {
                "name": "Ying Xu",
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            },
            {
                "name": "Lin Tang",
                "org": ""
            },
            {
                "name": "Yongjiong Jia",
                "org": ""
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        ],
        "title": "Molecular cloning and characterization of phospholipase D from Jatropha curcas",
        "keywords": [
            "Enzyme activity",
            "Expression",
            "Jatropha curcas",
            "Molecular cloning",
            "Phospholipase D"
        ],
        "venue": "Molecular Biology Reports",
        "year": 2010,
        "id": "SnIRjbvJ"
    },
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        "authors": [
            {
                "name": "Sheng-Liang Ye",
                "org": "College of Life Sciences"
            },
            {
                "name": "Feng Cai",
                "org": "College of Life Sciences"
            },
            {
                "name": "Xun-Lu Zhu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Xiao-Bo Qin",
                "org": "College of Life Sciences"
            },
            {
                "name": "Ying Xu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Fang Chen",
                "org": "College of Life Sciences"
            }
        ],
        "title": "Isolation, purification and analysis of some characters of peroxidase from leaves in Jatropha curcas L.",
        "keywords": [
            "Enzymatic character",
            "Jatropha curcas",
            "Peroxidase",
            "Purification",
            "Stability",
            "Stress"
        ],
        "venue": "Plant Physiology Communications",
        "year": 2010,
        "id": "DI4Weig9"
    },
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        "authors": [
            {
                "name": "Xun-Lu Zhu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Xi-Hong Zhu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Xiao-Ping Gu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Ying Xu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Fang Chen",
                "org": "College of Life Sciences"
            }
        ],
        "title": "Cloning and heterologous expression of a cytosolic class II small heat shock protein gene (JcHSP17.5) from Jatropha curcas L",
        "keywords": [
            "Gene expression",
            "Jatropha curcas",
            "Osmotolerance",
            "Small heat shock protein",
            "Thermotolerance"
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        "venue": "Plant Physiology Communications",
        "year": 2010,
        "id": "T64iaBov"
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        "authors": [
            {
                "name": "Xiaobo Qin",
                "org": "College of Life Sciences"
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            {
                "name": "Caixia Shao",
                "org": "College of Life Sciences"
            },
            {
                "name": "Pei Hou",
                "org": "College of Life Sciences"
            },
            {
                "name": "Jihai Gao",
                "org": "College of Life Sciences"
            },
            {
                "name": "Ningfei Lei",
                "org": "College of Materials and Chemistry and Chemical Engineering"
            },
            {
                "name": "Luding Jiang",
                "org": "College of Life Sciences"
            },
            {
                "name": "Shengliang Ye",
                "org": "College of Life Sciences"
            },
            {
                "name": "Chunbao Gou",
                "org": "College of Life Sciences"
            },
            {
                "name": "Shaoyin Luo",
                "org": "College of Life Sciences"
            },
            {
                "name": "Xiaojiang Zheng",
                "org": "College of Life Sciences"
            },
            {
                "name": "Xiaoping Gu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Xihong Zhu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Ying Xu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Fang Chen",
                "org": "College of Life Sciences"
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        ],
        "title": "Different functions and expression profiles of curcin and curcin-L in Jatropha curcas L.",
        "keywords": [
            "Antifungal activity",
            "Jatropha curcas L.",
            "Ribosome-inactivating protein"
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        "venue": "Zeitschrift fur Naturforschung - Section C Journal of Biosciences",
        "year": 2010,
        "id": "O4htQW66"
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        "authors": [
            {
                "name": "Min Yu",
                "org": ""
            },
            {
                "name": "Wenguo Wang",
                "org": ""
            },
            {
                "name": "Shenghua Wang",
                "org": ""
            },
            {
                "name": "Fang Chen",
                "org": ""
            }
        ],
        "title": "Alleviative effect of exogenous citric acid on rice under copper toxicity",
        "keywords": [
            "Alleviative effect",
            "Citric acid",
            "Copper toxicity",
            "Physiological property",
            "Rice"
        ],
        "venue": "Chinese Journal of Applied and Environmental Biology",
        "year": 2010,
        "id": "5B9AkKYW"
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    "cmN3zLaq": {
        "authors": [
            {
                "name": "Jun Wu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Yuan Liu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Lin Tang",
                "org": "College of Life Sciences"
            },
            {
                "name": "Fuli Zhang",
                "org": "College of Life Sciences"
            },
            {
                "name": "Fang Chen",
                "org": "College of Life Sciences"
            }
        ],
        "title": "A study on structural features in early flower development of jatropha curcas L. and the classification of its inflorescences",
        "keywords": [
            "Biofuel",
            "Flower",
            "Inflorescence",
            "Jatropha curcas",
            "Scanning electron microscopy",
            "Sex differentiation"
        ],
        "venue": "African Journal of Agricultural Research",
        "year": 2011,
        "id": "cmN3zLaq"
    },
    "xlg1nRrQ": {
        "authors": [
            {
                "name": "Xihong Zhu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Jian Liu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Xiaojiang Zheng",
                "org": "College of Life Sciences"
            },
            {
                "name": "Ying Xu",
                "org": "College of Life Sciences"
            },
            {
                "name": "Fang Chen",
                "org": "College of Life Sciences"
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        "title": "Regeneration of plantlets from mature endosperm of jatropha curcas L. and analysis of their stomata",
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        "venue": "Chinese Journal of Applied and Environmental Biology",
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        "title": "Metabolic profiling assisted quality assessment of Rhodiola rosea extracts by high-performance liquid chromatography",
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        "keywords": [
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        "keywords": [
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            "N2",
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            },
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            },
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            "Dismutase",
            "Luminescence",
            "Mechanism",
            "Prulifloxacin",
            "Spectrofluorimetry",
            "Superoxide",
            "Terbium"
        ],
        "venue": "Analytical Letters",
        "year": 2008,
        "id": "Rg6PVFjk"
    },
    "MyWhpUHS": {
        "authors": [
            {
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                "org": ""
            },
            {
                "name": "Lin Li",
                "org": ""
            },
            {
                "name": "Fang Chen",
                "org": ""
            }
        ],
        "title": "Determination of adenosine disodium triphosphate using prulifloxacin-terbium(III) as a fluorescence probe by spectrofluorimetry",
        "keywords": [
            "Adenosine disodium triphosphate",
            "Luminescence mechanism",
            "Prulifloxacin",
            "Spectrofluorimetry",
            "Terbium"
        ],
        "venue": "Analytica Chimica Acta",
        "year": 2008,
        "id": "MyWhpUHS"
    },
    "GX76PsQb": {
        "authors": [
            {
                "name": "Fengshan Yu",
                "org": "Department of Chemistry"
            },
            {
                "name": "Lanhua Chen",
                "org": "Department of Chemistry"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Chemistry"
            }
        ],
        "title": "Chemiluminescence method for the determination of mitoxantrone by the enhancement of the tris-(4,7-diphenyl-1,10-phenanthrolinedisulfonic acid)ruthenium(II)-cerium(IV) system",
        "keywords": [
            "Cerium(IV)",
            "Chemiluminescence",
            "Mitoxantrone",
            "Tris-(4,7-diphenyl-1,10-phenanthrolinedisulfonic acid)ruthenium(II)"
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        "venue": "Microchimica Acta",
        "year": 2008,
        "id": "GX76PsQb"
    },
    "v5noVI4g": {
        "authors": [
            {
                "name": "Fengshan Yu",
                "org": "Department of Chemistry"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Chemistry"
            },
            {
                "name": "Lanhua Chen",
                "org": "Department of Chemistry"
            }
        ],
        "title": "Direct chemiluminescence determination of fenbufen by the enhancement of the Ru(phen)3 2+-cerium(IV) system",
        "keywords": [
            "Cerium(IV)",
            "Chemiluminescence",
            "Fenbufen",
            "Ru(phen)3\n2+"
        ],
        "venue": "Microchimica Acta",
        "year": 2008,
        "id": "v5noVI4g"
    },
    "dHHqb3JW": {
        "authors": [
            {
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                "org": ""
            },
            {
                "name": "Zhen-Bo Liu",
                "org": ""
            },
            {
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                "org": ""
            },
            {
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                "org": ""
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                "org": ""
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                "org": ""
            },
            {
                "name": "Wei-Nv Lin",
                "org": ""
            },
            {
                "name": "Fang Chen",
                "org": ""
            }
        ],
        "title": "Determination of trace \u03b1-fetoprotein variant by affinity adsorption solid substrate-room temperature phosphorimetry",
        "keywords": [
            "\u03b1-fetoprotein variant",
            "Affinity adsorption solid substrate-room temperature phosphorimetry",
            "Concanavalin agglutinin",
            "Dendrimers-porphyrin"
        ],
        "venue": "Luminescence",
        "year": 2009,
        "id": "dHHqb3JW"
    },
    "fQr1GVaA": {
        "authors": [
            {
                "name": "Fengshan Yu",
                "org": "Department of Chemistry"
            },
            {
                "name": "Yangbin Zhang",
                "org": "Department of Chemistry"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Chemistry"
            },
            {
                "name": "Lanhua Chen",
                "org": "Department of Chemistry"
            }
        ],
        "title": "Chemiluminescence method for the determination of piroxicam by the enhancement of the tris-(4,7-diphenyl-1,10- Phenanthrolinedisulphonic acid) ruthenium(II) (RuBPS)-cerium(IV) system and its application",
        "keywords": [
            "Cerium(iv)",
            "Chemiluminescence",
            "Piroxicam",
            "Tris-(4,7-diphenyl-1,10-phenanthrolinedisulphonic acid) ruthenium(ii)"
        ],
        "venue": "Luminescence",
        "year": 2009,
        "id": "fQr1GVaA"
    },
    "uQNlxSBJ": {
        "authors": [
            {
                "name": "Fengshan Yu",
                "org": "Department of Chemistry"
            },
            {
                "name": "Man Cui",
                "org": "Department of Chemistry"
            },
            {
                "name": "Fang Chen",
                "org": "College of Chemistry and Chemical Engineering"
            },
            {
                "name": "Yongwei Gao",
                "org": "Department of Chemical Engineering"
            },
            {
                "name": "Juan Wei",
                "org": "School of Biotechnology and Food Engineering"
            },
            {
                "name": "Yanbin Ding",
                "org": "College of Chemistry and Material Science"
            }
        ],
        "title": "Highly sensitive spectrofluorimetric determination of trace amounts of folic acid using a oxytetracycline-terbium(III) probe",
        "keywords": [
            "Folic acid",
            "Oxytetracycline",
            "Spectrofluorimetry",
            "Terbium"
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        "venue": "Analytical Letters",
        "year": 2009,
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    },
    "xWHpS9F5": {
        "authors": [
            {
                "name": "Han Li",
                "org": "Department of Chemistry"
            },
            {
                "name": "Weimin Lu",
                "org": "Department of Chemistry"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Chemistry"
            },
            {
                "name": "Xue Dong",
                "org": "Department of Chemistry"
            },
            {
                "name": "Yihu Dai",
                "org": "Department of Chemistry"
            }
        ],
        "title": "Synthesis, structure, and magnetic properties of a self-assembled salicylaldimine neodymium(III) nitrate coordination polymer",
        "keywords": [
            "Coordination polymer",
            "Magnetic property",
            "Neodymium",
            "Self-assembly",
            "X-ray crystal structure"
        ],
        "venue": "Journal of Coordination Chemistry",
        "year": 2010,
        "id": "xWHpS9F5"
    },
    "it0osT9M": {
        "authors": [
            {
                "name": "Fang Chen",
                "org": "Department of Chemistry"
            },
            {
                "name": "Weimin Lu",
                "org": "Department of Chemistry"
            },
            {
                "name": "Yue Zhu",
                "org": "Department of Basic Medical Sciences"
            },
            {
                "name": "Bin Wu",
                "org": "Department of Chemistry"
            },
            {
                "name": "Xiaoming Zheng",
                "org": "Department of Chemistry"
            }
        ],
        "title": "Syntheses, crystal structures, and magnetic properties of RE(III)-Cu(II) heteronuclear complexes with -methylacrylic acid",
        "keywords": [
            "\u03b1-Methylacrylic acid",
            "Copper",
            "Crystal structure",
            "Magnetic property",
            "Rare earth"
        ],
        "venue": "Journal of Coordination Chemistry",
        "year": 2010,
        "id": "it0osT9M"
    },
    "Bv3hyrNP": {
        "authors": [
            {
                "name": "Yunyang Chen",
                "org": "Department of Chemistry"
            },
            {
                "name": "Debi Zhou",
                "org": "Department of Chemistry"
            },
            {
                "name": "Meisheng Wen",
                "org": "Department of Chemistry"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Chemistry"
            },
            {
                "name": "Longhui Tan",
                "org": "Department of Chemistry"
            },
            {
                "name": "Jianhong Jiang",
                "org": "Department of Chemistry"
            }
        ],
        "title": "Reduction kinetic of Ce(IV)/Ce(III) couple in methanesulfonic acid",
        "keywords": [
            "Ce(IV)/Ce(III)",
            "Kinetic",
            "Methanesulfonic acid",
            "Rare earths"
        ],
        "venue": "Zhongguo Xitu Xuebao/Journal of the Chinese Rare Earth Society",
        "year": 2010,
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    },
    "EtvjkUJ1": {
        "authors": [
            {
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                "org": ""
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                "org": ""
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                "org": ""
            },
            {
                "name": "Fang Chen",
                "org": ""
            }
        ],
        "title": "A highly sensitive label-free resonance light scattering assay of carcinoembryonic antigen based on immune complexes",
        "keywords": [
            "Carcinoembryonic antigen",
            "Immunoreaction",
            "Resonance light scattering",
            "Tumor marker"
        ],
        "venue": "Analytica Chimica Acta",
        "year": 2012,
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    },
    "VUtReJ2P": {
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                "org": ""
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                "org": ""
            },
            {
                "name": "Jian-Nong Ye",
                "org": ""
            }
        ],
        "title": "Sensitive determination of chloroanilines in water samples by hollow fiber-based liquid-phase microextraction prior to capillary electrophoresis with amperometric detection",
        "keywords": [
            "Amperometric detection",
            "Aniline compound",
            "CE",
            "Hollow fiber-based liquid-phase microextraction (HF-LPME)",
            "Water analysis"
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    "L8bfalGx": {
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                "org": ""
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                "org": ""
            },
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                "org": ""
            }
        ],
        "title": "Solvent-free synthesis of silicoaluminophosphate zeolites",
        "keywords": [
            "aluminophosphates",
            "silicoaluminophosphates",
            "solvent-free synthesis",
            "synthetic methods",
            "zeolites"
        ],
        "venue": "Angewandte Chemie - International Edition",
        "year": 2013,
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    },
    "eDzSKaWl": {
        "authors": [
            {
                "name": "Ying Li",
                "org": ""
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            {
                "name": "Fang Chen",
                "org": ""
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                "org": ""
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                "org": ""
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                "org": ""
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            {
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                "org": ""
            }
        ],
        "title": "Fast determination of aldehyde preservatives by miniaturized capillary electrophoresis with amperometric detection",
        "keywords": [
            "2-Thiobarbituric acid derivatization",
            "Aldehyde preservative",
            "Miniaturized CE",
            "Moving chemical reaction boundary",
            "Online enrichment"
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        "venue": "Electrophoresis",
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    },
    "MzHnN7mz": {
        "authors": [
            {
                "name": "Hemi Luan",
                "org": "Department of Chemistry"
            },
            {
                "name": "Nan Meng",
                "org": "BGI-Shenzhen"
            },
            {
                "name": "Ping Liu",
                "org": "BGI-Shenzhen"
            },
            {
                "name": "Qiang Feng",
                "org": "BGI-Shenzhen"
            },
            {
                "name": "Shuhai Lin",
                "org": "Department of Chemistry"
            },
            {
                "name": "Jin Fu",
                "org": "BGI-Shenzhen"
            },
            {
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                "org": "School of Biosciences"
            },
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                "org": "BGI-Shenzhen"
            },
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                "org": "BGI-Shenzhen"
            },
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                "org": "BGI-Shenzhen"
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                "org": "BGI-Shenzhen"
            },
            {
                "name": "Xun Xu",
                "org": "BGI-Shenzhen"
            },
            {
                "name": "Zongwei Cai",
                "org": "Department of Chemistry"
            },
            {
                "name": "Jun Wang",
                "org": "Department of Biology"
            }
        ],
        "title": "Pregnancy-induced metabolic phenotype variations in maternal plasma",
        "keywords": [
            "maternal plasma",
            "metabolic phenotype",
            "metabolomics",
            "pregnancy",
            "variations"
        ],
        "venue": "Journal of Proteome Research",
        "year": 2014,
        "id": "MzHnN7mz"
    },
    "ikrICVgq": {
        "authors": [
            {
                "name": "Fang Chen",
                "org": "Department of Chemistry and Environmental Engineering"
            },
            {
                "name": "Hui-Yang Yi",
                "org": "Department of Chemistry and Environmental Engineering"
            },
            {
                "name": "Yi-Ming Wu",
                "org": "Department of Chemistry and Environmental Engineering"
            }
        ],
        "title": "Synergistic degradation of reactive brilliant orange with H2O2 /TiO2/ ultrasound",
        "keywords": [
            "Degradation",
            "Reactive brilliant orange",
            "Synergetic effect",
            "Titanium dioxide",
            "Ultrasound"
        ],
        "venue": "Yingxiang Kexue yu Guanghuaxue/Imaging Science and Photochemistry",
        "year": 2010,
        "id": "ikrICVgq"
    },
    "JCgODR2g": {
        "authors": [
            {
                "name": "Fanghong Tong",
                "org": "Department of Chemistry, East China Normal University"
            },
            {
                "name": "Yang Zhang",
                "org": "Department of Chemistry, East China Normal University"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Chemistry, East China Normal University"
            },
            {
                "name": "Ying Li",
                "org": "Department of Chemistry, East China Normal University"
            },
            {
                "name": "Guanhua Ma",
                "org": "Department of Chemistry, East China Normal University"
            },
            {
                "name": "Yanping Chen",
                "org": "Department of Chemistry, East China Normal University"
            },
            {
                "name": "Kun Liu",
                "org": "Department of Chemistry, East China Normal University"
            },
            {
                "name": "Jiaming Dong",
                "org": "Department of Chemistry, East China Normal University"
            },
            {
                "name": "Jiannong Ye",
                "org": "Department of Chemistry, East China Normal University"
            },
            {
                "name": "Qingcui Chu",
                "org": "Department of Chemistry, East China Normal University"
            }
        ],
        "title": "Hollow-fiber liquid-phase microextraction combined with capillary electrophoresis for trace analysis of sulfonamide compounds",
        "keywords": [
            "Capillary electrophoresis",
            "Electrochemical detection",
            "Hollow-fiber liquid-phase microextraction",
            "Sulfonamides",
            "Water analysis"
        ],
        "venue": "Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences",
        "year": 2013,
        "id": "JCgODR2g"
    },
    "McxPcFKG": {
        "authors": [
            {
                "name": "Fang Chen",
                "org": ""
            },
            {
                "name": "Chunqiu Wang",
                "org": ""
            },
            {
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                "org": ""
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                "org": ""
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                "org": ""
            }
        ],
        "title": "Sensitive determination of endogenous hexanal and heptanal in urine by hollow-fiber liquid-phase microextraction prior to capillary electrophoresis with amperometric detection",
        "keywords": [
            "Amperometric detection",
            "Capillary zone electrophoresis",
            "Heptanal",
            "Hexanal",
            "Hollow-fiber liquid-phase microextraction",
            "Human urine"
        ],
        "venue": "Talanta",
        "year": 2014,
        "id": "McxPcFKG"
    },
    "7ZZJRHXU": {
        "authors": [
            {
                "name": "Fengshan Yu",
                "org": "Department of Chemistry, Hubei Key Laboratory of Bioinorganic Chemistry and Materia Medica"
            },
            {
                "name": "Lin Li",
                "org": "HuBei Research Institute of Chemistry"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Chemistry, Hubei Key Laboratory of Bioinorganic Chemistry and Materia Medica"
            },
            {
                "name": "Weizhou Liu",
                "org": "Department of Chemistry, Hubei Key Laboratory of Bioinorganic Chemistry and Materia Medica"
            }
        ],
        "title": "Terbium sensitized chemiluminescence of potassium permanganate-sodium thiosulfateprulifloxacin system and its application",
        "keywords": [
            "Chemiluminescence",
            "Potassium permanganate",
            "Prulifloxacin",
            "Sodium thiosulfate"
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        "venue": "Analytical Letters",
        "year": 2010,
        "id": "7ZZJRHXU"
    },
    "hpiu7v7e": {
        "authors": [
            {
                "name": "Xiaoping Yu",
                "org": "Department of Nutrition and Food Hygiene"
            },
            {
                "name": "Zhaoxia Xu",
                "org": "Department of Nutrition and Food Hygiene"
            },
            {
                "name": "Mantian Mi",
                "org": "Department of Nutrition and Food Hygiene"
            },
            {
                "name": "Hongxia Xu",
                "org": "Department of Nutrition and Food Hygiene"
            },
            {
                "name": "Jundong Zhu",
                "org": "Department of Nutrition and Food Hygiene"
            },
            {
                "name": "Na Wei",
                "org": "Department of Nutrition and Food Hygiene"
            },
            {
                "name": "Ka Chen",
                "org": "Department of Nutrition and Food Hygiene"
            },
            {
                "name": "Qianyong Zhang",
                "org": "Department of Nutrition and Food Hygiene"
            },
            {
                "name": "Kaihong Zeng",
                "org": "Department of Nutrition and Food Hygiene"
            },
            {
                "name": "Jian Wang",
                "org": "Department of Nutrition"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Nutrition and Food Hygiene"
            },
            {
                "name": "Yong Tang",
                "org": "Department of Nutrition and Food Hygiene"
            }
        ],
        "title": "Dietary taurine supplementation ameliorates diabetic retinopathy via anti-excitotoxicity of glutamate in streptozotocin-induced sprague-dawley rats",
        "keywords": [
            "Diabetic retinopathy",
            "Glial fibrillary acidic protein",
            "Glutamate",
            "Glutamate transporter",
            "N-methyl-d-aspartate receptor subunit 1",
            "Taurine"
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        "year": 2008,
        "id": "hpiu7v7e"
    },
    "gfYrkJLs": {
        "authors": [
            {
                "name": "Kaihong Zeng",
                "org": "Department of Nutrition and Food Hygiene"
            },
            {
                "name": "Hongxia Xu",
                "org": "Department of Nutrition and Food Hygiene"
            },
            {
                "name": "Mantian Mi",
                "org": "Department of Nutrition and Food Hygiene"
            },
            {
                "name": "Qianyong Zhang",
                "org": "Department of Nutrition and Food Hygiene"
            },
            {
                "name": "Yajie Zhang",
                "org": "Department of Nutrition and Food Hygiene"
            },
            {
                "name": "Ka Chen",
                "org": "Department of Nutrition and Food Hygiene"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Nutrition and Food Hygiene"
            },
            {
                "name": "Jundong Zhu",
                "org": "Department of Nutrition and Food Hygiene"
            },
            {
                "name": "Xiaoping Yu",
                "org": "Department of Nutrition and Food Hygiene"
            }
        ],
        "title": "Dietary taurine supplementation prevents glial alterations in retina of diabetic rats",
        "keywords": [
            "Diabetes",
            "Glial fibrillary acid protein",
            "Glutamate decarboxylase",
            "Glutamate transporter",
            "Glutamine synthetase",
            "M\u00fcller cells",
            "Taurine",
            "Vascular endothelial growth factor"
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        "year": 2009,
        "id": "gfYrkJLs"
    },
    "ntG3znKL": {
        "authors": [
            {
                "name": "Fang Chen",
                "org": "Department of Nutrition and Food Hygiene"
            },
            {
                "name": "Mantian Mi",
                "org": "Department of Nutrition and Food Hygiene"
            },
            {
                "name": "Ka Chen",
                "org": "Department of Nutrition and Food Hygiene"
            },
            {
                "name": "Hongxia Xu",
                "org": "Department of Nutrition and Food Hygiene"
            }
        ],
        "title": "The effects of taurine on hypoxia-induced retinal M\u00fcller cell cytoskeleton damage in rat",
        "keywords": [
            "Cytoskeleton",
            "Hypoxia",
            "Retina",
            "Taurine"
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        "venue": "Chinese Ophthalmic Research",
        "year": 2009,
        "id": "ntG3znKL"
    },
    "6fgfh61n": {
        "authors": [
            {
                "name": "Ka Chen",
                "org": "Department of Nutrition and Food Hygiene"
            },
            {
                "name": "Qianyong Zhang",
                "org": "Department of Nutrition and Food Hygiene"
            },
            {
                "name": "Jian Wang",
                "org": "Department of Nutrition and Food Hygiene"
            },
            {
                "name": "Fengjin Liu",
                "org": "Department of Nutrition and Food Hygiene"
            },
            {
                "name": "Mantian Mi",
                "org": "Department of Nutrition and Food Hygiene"
            },
            {
                "name": "Hongxia Xu",
                "org": "Department of Nutrition and Food Hygiene"
            },
            {
                "name": "Fang Chen",
                "org": "Department of Nutrition and Food Hygiene"
            },
            {
                "name": "Kaihong Zeng",
                "org": "Department of Nutrition and Food Hygiene"
            }
        ],
        "title": "Taurine protects transformed rat retinal ganglion cells from hypoxia-induced apoptosis by preventing mitochondrial dysfunction",
        "keywords": [
            "Apoptosis",
            "Hypoxia",
            "Mitochondria",
            "Retinal ganglion cell line",
            "Taurine"
        ],
        "venue": "Brain Research",
        "year": 2009,
        "id": "6fgfh61n"
    },
    "xXZqvmyi": {
        "authors": [
            {
                "name": "Fang Chen",
                "org": "Department of Nutrition and Food Hygiene"
            },
            {
                "name": "Mantian Mi",
                "org": "Department of Nutrition and Food Hygiene"
            },
            {
                "name": "Qianyong Zhang",
                "org": "Department of Nutrition and Food Hygiene"
            },
            {
                "name": "Na Wei",
                "org": "Department of Nutrition and Food Hygiene"
            },
            {
                "name": "Ka Chen",
                "org": "Department of Nutrition and Food Hygiene"
            },
            {
                "name": "Hongxia Xu",
                "org": "Department of Nutrition and Food Hygiene"
            },
            {
                "name": "Jialin Yuan",
                "org": "Department of Nutrition and Food Hygiene"
            },
            {
                "name": "Yong Zhou",
                "org": "Department of Nutrition and Food Hygiene"
            },
            {
                "name": "Haibin Lang",
                "org": "Department of Nutrition and Food Hygiene"
            },
            {
                "name": "Xiaoping Yu",
                "org": "Department of Nutrition and Food Hygiene"
            },
            {
                "name": "Bin Wang",
                "org": "Department of Nutrition and Food Hygiene"
            },
            {
                "name": "Jian Wang",
                "org": "Department of Nutrition and Food Hygiene"
            },
            {
                "name": "Yong Tang",
                "org": "Department of Nutrition and Food Hygiene"
            },
            {
                "name": "Hui Chang",
                "org": "Department of Nutrition and Food Hygiene"
            }
        ],
        "title": "Taurine buffers glutamate homeostasis in retinal cells in vitro under hypoxic conditions",
        "keywords": [
            "Glutamate",
            "Hypoxia",
            "M\u00fcller cell",
            "Retina",
            "Taurine"
        ],
        "venue": "Ophthalmic Research",
        "year": 2010,
        "id": "xXZqvmyi"
    },
    "DnIZeZDR": {
        "authors": [
            {
                "name": "Peter Rautenberg",
                "org": "Inst. Med. Mikrobiol. und Virologie"
            },
            {
                "name": "Christoph L\u00fcbbert",
                "org": "Inst. Med. Mikrobiol. und Virologie"
            },
            {
                "name": "Wiebke Weers",
                "org": "Inst. Med. Mikrobiol. und Virologie"
            },
            {
                "name": "Eric Boetel",
                "org": "Inst. Med. Mikrobiol. und Virologie"
            },
            {
                "name": "J\u00f6rg Schweichler",
                "org": "Inst. Med. Mikrobiol. und Virologie"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Microbiology"
            },
            {
                "name": "Angelika Costard-J\u00e4ckle",
                "org": "Klin. Herz- und Gefa\u00dfchirurgie"
            },
            {
                "name": "Heike Kraemer-Hansen",
                "org": "Klin. Allg. Chir. Thoraxchirurgie"
            },
            {
                "name": "Timm C. Harder",
                "org": "Inst. Med. Mikrobiol. und Virologie"
            }
        ],
        "title": "Evaluation of the AmpliSensor PCR and the SHARP signal detection system for the early prediction of symptomatic CMV infection in solid transplant recipients",
        "abstract": "Background: Cytomegalovirus (CMV) is associated with high morbidity and mortality in transplant patients. Specific antiviral treatment at an early stage of CMV infection may effectively ameliorate, but not eliminate CMV disease in these patients. Presently, the pp65 antigenemia test on peripheral leukocytes is the method most widely used for predicting and monitoring transplant patients for active CMV infection. Nucleic acid amplification methods are less well defined since they lack standardisation. Objective: A seminested fluorometric PCR assay (AmpliSensor-CMV, BAG, Germany) and a one-step PCR with a signal-amplification step (SHARP, Abbott, Germany) specific for the fragments of the CMV UL 122 and UL 123 genes, respectively, were evaluated for the early diagnosis of CMV infection. Design: A total of 26 recipients of heterogeneous solid organs were monitored prospectively for a median of 99 days after transplantation. By testing 371 clinical samples parallel with the pp65-antigen assay and IgM and IgG EIA assays the sensitivity, specificity, correlation and quantitation potential of both PCRs was evaluated. Results: Eight out of 26 patients developed active CMV infection. A total of 48 samples of these patients exceeded a CMV-DNA load threshold of 15 genome equivalents/10\n                        ",
        "keywords": [
            "AmpliSensor PCR",
            "Detection system",
            "Quantitative PCR monitoring",
            "SHARP signal",
            "Solid organ recipients"
        ],
        "venue": "Journal of Clinical Virology",
        "year": 1999,
        "id": "DnIZeZDR"
    },
    "dsffF2Ah": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "T.C. Harder",
                "org": ""
            },
            {
                "name": "U. Ullmann",
                "org": ""
            },
            {
                "name": "P. Rautenberg",
                "org": ""
            }
        ],
        "title": "Rapid detection by reverse hybridization of mutations in the UL97 gene of human cytomegalovirus conferring resistance to ganciclovir",
        "abstract": "Background of study: Diseases due to human cytomegalovirus (HCMV) infection constitute a major threat in marrow and solid organ transplant recipients. Ganciclovir (GCV) is widely used in prophylaxis and pre-emptive therapy of active HCMV infection. Resistance to ganciclovir (GCV) may arise at variable frequency under GCV therapy and is conferred by mutations (i) in the UL97 gene (codons 460, 520, and 591-607) encoding a phosphotransferase which is essential for monophosphorylation of GCV and, to a lesser extent, (ii) in the UL54 gene coding for the DNA polymerase of HCMV. Objective: The purpose was to develop a rapid assay to screen for emerging GCV resistance mutations in the UL97 gene of HCMV whereby avoiding virus isolation and nucleotide sequencing procedures. Study design: A nested PCR (nPCR) amplifying UL97 codons 450-672 was developed. Nested amplicons were subsequently sequenced directly. Oligonucleotides for use in a reverse hybridization assay were designed to detect relevant non-synonymous mutations at codons UL97 460, 520, 603 and 607. Strain AD169 served as a wild-type control. Results: UL97-specific nPCR amplicons were obtained from 18 EDTA blood samples of ten transplant recipients receiving GCV for more than 30 days. In three consecutive samples from a single patient a GCV resistance mutation at codon 603 (C\u2192W) was detected. In addition, two out of four cell culture-adapted HCMV isolates known to exhibit GCV resistance in vitro revealed mutations at codons 460 (M\u2192V) and 607 (C\u2192Y), respectively. By reverse hybridization a discrimination of single nucleotide changes at codons 460, 520, 603 and 607 was possible whereby matching exactly the results of the nucleotide sequence analysis for all 23 amplicons examined. Conclusions: Reverse hybridization appeared to be a rapid and convenient alternative to nucleotide sequencing when screening the UL97 gene of HCMV for selected markers of GCV resistance.",
        "keywords": [
            "Ganciclovir resistance",
            "Human cytomegalovirus",
            "Reverse hybridization",
            "Transplantation medicine"
        ],
        "venue": "Journal of Clinical Virology",
        "year": 1999,
        "id": "dsffF2Ah"
    },
    "aUVtxH6A": {
        "authors": [
            {
                "name": "Shu-Sen Zheng",
                "org": "Institute of Organ Transplantation"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Microbiology"
            },
            {
                "name": "Jing Qian",
                "org": "Department of Microbiology"
            },
            {
                "name": "Ting Cai",
                "org": "Department of Microbiology"
            },
            {
                "name": "Jun Fan",
                "org": "Institute of Organ Transplantation"
            },
            {
                "name": "Wei-Hang Ma",
                "org": "Institute of Organ Transplantation"
            }
        ],
        "title": "Cytomegalovirus glycoprotein B sequence variation in Chinese liver transplant recipients",
        "abstract": "Objective: To investigate human cytomegalovirus infection and genetic variations in glycoprotein B (gB) in liver transplant recipients in south-east China. Methods: EDTA-blood samples were obtained from 21 liver transplant recipients. The semi - nested PCR was used to amplify a region of high sequence variability in the gB gene of human cytomegalovirus (HCMV) followed by direct sequence analysis. Results: Out of the 21 liver transplant recipients, 5 were proved HCMV positive 62 to 180 days after transplantation. The nucleotide and encoded amino acid sequences were compared with published sequences of AD169 and Towne laboratory strains. Within the region sequenced, 2 out of 5 strains possessed a peptide configuration similar to that of strain AD169, while another 2 strains displayed a peptide configuration similar to that of strain Towne. One strain had amino acid substitution, which was different from those of both AD169 and Towne in the cleavage site. Conclusion: Our results provide molecular epidemiological data for HCMV strains circulating among transplant recipients in south-east China.",
        "keywords": [
            "Glycoprotein B",
            "Human cytomegalovirus",
            "Liver transplantation"
        ],
        "venue": "Hepatobiliary and Pancreatic Diseases International",
        "year": 2002,
        "id": "aUVtxH6A"
    },
    "3UNPv8QW": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "First Affil. Hosp. Med. Coll. Z."
            },
            {
                "name": "Jing Qian",
                "org": ""
            },
            {
                "name": "Ting Cai",
                "org": ""
            },
            {
                "name": "Weihang Ma",
                "org": ""
            },
            {
                "name": "Shusen Zheng",
                "org": ""
            },
            {
                "name": "U. Ullmann",
                "org": ""
            },
            {
                "name": "P. Rautenburg",
                "org": ""
            },
            {
                "name": "T.C. Harder",
                "org": ""
            }
        ],
        "title": "Fast detection of human cytomegalovirus and differentiation of glycoprotein B and H genotypes by PCR-assisted reverse hybridization",
        "abstract": "Objective To establish a simple, fast, sensitive and specific method for the identification of human cytomegalovirus and the differentiation of glycoprotein B and H genotypes. Methods Based on the sequences of highly variable regions of glycoprotein H N-terminus(gH), glycoproteins B N-teiminus(gBn) and the gB endoprotease cleavage site(gBclv), nested PCRs for the detection of HCMV were established. Nucleotide sequencing and PCR-assisted reverse hybridization assay using 17 specific oligonucleotide probes were performed and compared to differentiate gB and gH genotypes from 23 Chinese and 6 German transplant recipients with active HCMV infection. Results In Chinese patients, HCMV strains expressing the gH genotypes 1 and 2 and the gBn/gBclv genotypes 1,2 and 3 were identified. In addition to these genotypes, gBn/clv genotype 4 was also found in German but not in Chinese recipients. Both Chinese and German recipients co-infected with more than one genotype. Reverse hybridization was superior to nucleotide sequencing in detecting co-infections with different HCMV strains. Conclusion PCR-assisted reverse hybridization is a simple, fast and specific technique for identification of HCMV and the differentiation of glycoprotein B and H genotypes.",
        "keywords": [
            "Human cytomegalovirus",
            "Polymerase chain reaction",
            "Reverse hybridization"
        ],
        "venue": "Chinese Journal of Microbiology and Immunology",
        "year": 2002,
        "id": "3UNPv8QW"
    },
    "dSKiTBpW": {
        "authors": [
            {
                "name": "Wen-Ping Gu",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Wei Liu",
                "org": ""
            },
            {
                "name": "Qi-Dong Yang",
                "org": ""
            },
            {
                "name": "Gui-Fang Cao",
                "org": ""
            },
            {
                "name": "Guang-Jie Xie",
                "org": ""
            },
            {
                "name": "Jie Yang",
                "org": ""
            },
            {
                "name": "Yan-Hong Zhou",
                "org": ""
            }
        ],
        "title": "Effect of flunarizine on HSP70 gene expression for following transient ischemia",
        "keywords": [
            "Cerebral ischemia",
            "Funarizine",
            "HSP70"
        ],
        "venue": "Chinese Journal of Clinical Rehabilitation",
        "year": 2002,
        "id": "dSKiTBpW"
    },
    "quQClhKj": {
        "authors": [
            {
                "name": "Ting Cai",
                "org": "Med. School of Zhejiang University"
            },
            {
                "name": "Jing Qian",
                "org": "Med. School of Zhejiang University"
            },
            {
                "name": "Hangmei Jin",
                "org": "Med. School of Zhejiang University"
            },
            {
                "name": "Lin Zhou",
                "org": "Med. School of Zhejiang University"
            },
            {
                "name": "Jun Lin",
                "org": "Med. School of Zhejiang University"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Med. School of Zhejiang University"
            }
        ],
        "title": "Genotyping of glycoprotein B of human cytomegalovirus clinical strains",
        "abstract": "Objective. To investigate genotypes of glycoprotein B of human cytomegalovirus clinical strains. Methods. Cytomegalovirus gB N-terminus (gBn, 54-485nt) gene and gB endoprotease cleavage site (gBcls, 1 284-1 600nt) gene in blood samples of bone marrow and solid organ transplant recipients and reproductive tissues of tubal pregnancy were amplified by nested-PCR. Positive samples were directly sequenced to identify genotype. Results. HCMV gB amplificates were detected in 19 strains of transplant recipients and 25 strains of tubal pregnancy. Sequence analysis of 32 positive gBn fragments showed that 8 strains (25%) were gBn1 genotypes, 2 strains (6%) of gBn2 genotypes, 22 strains (69%) of gBn3 genotypes, gBn4 genotype was not detected. The gBn3 genotype was dominant. In 26 positive gBcls fragments sequence analysis, results showed that 14 strains (54%) were gBcls1 genotypes, 5 strains (20%) of gBcls2 genotypes, 7 strains(26%) of gBcls3 genotypes, gBcls4 genotype was not detected. gBcls1 genotype was dominant. In 21 strains, the gBn type appeared different from gBcls type. 8 strains (36%) appeared gBcls1-gBn3. Conclusions. This study demonstrated the gBn3 genotype of glycoprotein B of human cytomegalovirus clinical strains from transplant recipients and tubal pregnancy. The intragenic variability within the gB gene was explained, as a result of homologous recombination.",
        "keywords": [
            "Cytomegalovirus",
            "Genotype",
            "Glycoprotein R"
        ],
        "venue": "Chinese Journal of Microbiology and Immunology",
        "year": 2003,
        "id": "quQClhKj"
    },
    "3NvBXMCA": {
        "authors": [
            {
                "name": "Lie-Ying Fan",
                "org": ""
            },
            {
                "name": "Ye Zhu",
                "org": ""
            },
            {
                "name": "Ren-Qian Zhong",
                "org": ""
            },
            {
                "name": "Xiao-Qing Tu",
                "org": ""
            },
            {
                "name": "Qu-Bo Chen",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Hai-Ying Liu",
                "org": ""
            },
            {
                "name": "Xian-Tao Kong",
                "org": ""
            }
        ],
        "title": "Study on the relationship of CTLA-4 -318, +49 polymorphisms with autoimmune hepatitis and primary biliary cirrhosis in a Chinese population",
        "abstract": "Objective: To investigate the association between Chinese patients with autoimmune hepatitis (AIH), primary biliary cirrhosis (PBC) and the polymorphisms of cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) gene promoter (-318) and exon 1 (+ 49). Methods: The CTLA-4 promoter (-318 T/C) and exon 1 (+49A/G) polymorphisms were genotyped via restriction fragment length polymorphism methods in 62 Chinese AIH patients, 77 Chinese PBC patients and 160 healthy controls. Results: There was no difference in the distribution of CTLA-4 promoter -318 T/C polymorphisms between AIH patients and controls, but the C allele frequency was significantly increased in patients with AIH, compared to controls (P = 0.02, OR = 2.43). The distribution of CTLA-4 gene exon 1 49 A/G genotypes exhibited significant difference between PBC patients and controls (P = 0.006), and the frequency of G allele showed a significant increase in PBC group as compared with controls (P = 0.0046, OR = 1.8). Although the genotype distribution of the CTLA-4 exon 1-promoter gene displayed no significant difference between AIH and PBC patients and controls, the occurrence of GG-CC was increased in the patients of the two groups (AIH: 32.3%, PBC: 37.7%; control: 22.5%). Conclusion: The above findings suggest that the polymorphisms of CTLA-4 gene probably confer susceptibility to AIH and PBC in the Chinese population.",
        "keywords": [
            "Autoimmune hepatitis",
            "Cytotoxic T lymphocyte-associated antigen-4",
            "Genetic polymorphism",
            "Primary biliary cirrhosis"
        ],
        "venue": "Chinese Journal of Medical Genetics",
        "year": 2004,
        "id": "3NvBXMCA"
    },
    "8OlgvfEy": {
        "authors": [
            {
                "name": "Lieying Fan",
                "org": "Center of Clinical Immunology, Changzheng Hospital"
            },
            {
                "name": "Xiaoqing Tu",
                "org": "Center of Clinical Immunology, Changzheng Hospital, Second Military Medical University"
            },
            {
                "name": "Ye Zhu",
                "org": "Center of Clinical Immunology, Changzheng Hospital, Second Military Medical University"
            },
            {
                "name": "Lin Zhou",
                "org": "Center of Clinical Immunology, Changzheng Hospital, Second Military Medical University"
            },
            {
                "name": "Thomas Pfeiffer",
                "org": "Euroimmun, Medical Laboratory Diagnostic"
            },
            {
                "name": "Ralph Feltens",
                "org": "Euroimmun, Medical Laboratory Diagnostic"
            },
            {
                "name": "Winfried Stoecker",
                "org": "Euroimmun, Medical Laboratory Diagnostic"
            },
            {
                "name": "Renqian Zhong",
                "org": "Center of Clinical Immunology, Changzheng Hospital, Second Military Medical University"
            }
        ],
        "title": "Genetic association of vitamin D receptor polymorphisms with autoimmune hepatitis and primary biliary cirrhosis in the Chinese",
        "abstract": "Background: Autoimmune hepatitis (AIH) and primary biliary cirrhosis (PBC) are two autoimmune diseases of unknown etiology. Genetic factors appear to be involved in the pathogenesis of both diseases. Vitamin D has been shown to exert multiple immunomodulatory effects, which acts through its own receptor (VDR). Polymorphisms of VDR had been implicated in several autoimmune diseases. In the present study, the association between Chinese patients with AIH, PBC and the polymorphisms in exon 2, intron 8 and exon 9 of vitamin D receptor genes was studied. Methods: Four candidate gene loci were investigated in 49 patients with AIH, 58 patients with PBC, and 160 healthy controls. The VDR polymorphisms were assessed by FokI, BsmI, ApaI, and TaqI endonuclease digestion after specific polymerase chain reaction (PCR) amplification. Results: The result show a significant difference in FokI polymorphism between AIH patients and controls (\u03c7",
        "keywords": [
            "Autoimmune hepatitis",
            "Gene susceptibility",
            "Polymorphisms",
            "Primary biliary cirrhosis",
            "VDR"
        ],
        "venue": "Journal of Gastroenterology and Hepatology (Australia)",
        "year": 2005,
        "id": "8OlgvfEy"
    },
    "KdJmr32k": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Department of Neurology"
            },
            {
                "name": "Qi-Dong Yang",
                "org": "Department of Neurology"
            },
            {
                "name": "Meng-Shi Yuan",
                "org": "Department of Neurology"
            },
            {
                "name": "Zhi-Jian Ma",
                "org": "Institute of Anatomy"
            },
            {
                "name": "De-Ren Hou",
                "org": "Department of Neurology"
            },
            {
                "name": "Xing-Lin Tan",
                "org": "Department of Neurology"
            }
        ],
        "title": "Effect of tuber fleeceflower root on disorders of learning and memory and neuronal apoptosis in hippocampi induced by beta-amyloid",
        "abstract": "Aim: To investigate both the significance of apoptosis in the pathogenesis of Alzheimer disease (AD) induced by beta-amyloid (A\u03b2) and the effect of tuber fleeceflower root (TFT) on the neurotoxicity of A\u03b2 in rats brain. Methods: The experiment was performed in the Department of Human Anatomy of Xiangya Medical School from September 2002 to February 2003. 40 SD rats were selected, 4 rats were abandoned by Y maze test, and 36 rats were randomly divided into saline groups, sham operation group and TFT group. The AD rat model was established by infection of A\u03b21-40 into right hippocampus of rats and was fed with TFT. Learning and memory ability was estimated with Y-electric maze at different time, the expression of positive Bcl-2 in hippocampus were detected with immunohistochemistry method. The apoptosis neurons were estimated with TUNEL method. Results: The experiment showed that the frequency of attempting learning and memory was 27.8 \u00b1 7.5, the expression of Bcl-2 was 8.71 \u00b1 1.83, and apoptosis neurons was 13.83 \u00b1 3.26 in model rats. The frequency of attempting learning and memory was 15.2 \u00b1 2.9, the expression of Bcl-2 was 13.5 \u00b1 2.17, apoptosis neurons was 9.57 \u00b1 2.16 in the TFT group. But there was significant difference as compared with control group (P < 0.01). Conclusion: The injection of A\u03b21-40 into hippocampus of rats can cause the injury of learning and memory abilities, which relates to that the expression of Bcl-2 is inhibited, which induces apoptosis occurring in model rat. TFT can protect learning and memory abilities, which may relate to inhibit the apoptosis in AD rats hippocampus induced by A\u03b2 through accelerating the expression of Bcl-2.",
        "keywords": [
            ""
        ],
        "venue": "Chinese Journal of Clinical Rehabilitation",
        "year": 2005,
        "id": "KdJmr32k"
    },
    "dc6xFhvR": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Zhihua Ding",
                "org": ""
            }
        ],
        "title": "Enhancement of depth resolution in optical coherence tomography by apodization",
        "abstract": "In this paper we introduce a method to increase the axial resolution in optical coherence tomography (OCT) by combining coherence gating with apodization through an appropriate pupil filter. In the proposed probe of our OCT system, the width of the central lobe of the axial point spread function is apodized to be within the coherence length of the light source, while its side-lobes are lying outside without contributing to coherence imaging. It comes to a conclusion that we can obtain improved resolution in OCT system without recurring to broadening the bandwidth of light source, which is nevertheless costing and inconvenient in implementation.",
        "keywords": [
            "Apodization",
            "Axial resolution",
            "Optical coherence tomography (OCT)",
            "Pupil filter"
        ],
        "venue": "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
        "year": 2005,
        "id": "dc6xFhvR"
    },
    "hKW8MaeG": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "State Key Lab. of Modern Optical Instrumentation"
            },
            {
                "name": "Zhihua Ding",
                "org": "State Key Lab. of Modern Optical Instrumentation"
            },
            {
                "name": "Xiaofeng Yu",
                "org": "State Key Lab. of Modern Optical Instrumentation"
            }
        ],
        "title": "Axial superresolution in optical coherence tomography through the combination of apodization and coherence gating",
        "abstract": "Axial resolution in optical coherence tomography (OCT) imaging is determined by the coherence length of light source and the beam-focusing condition. The most adopted approach for achieving high axial resolution in OCT is using a light source with a broaden bandwidth. A method to increase the axial resolution in OCT by combining coherence gating with apodization through an appropriate pupil filter is introduced. In the proposed OCT system, the width of central lobe of axial point spread function is apodized to be within the coherence length of light source, while its side-lobes are lying outside without contributing to coherence imaging. It is in this way that improved resolution can be obtained in OCT system without recurring to broadening the bandwidth of light source, which is nevertheless costing and inconvenient in implementation.",
        "keywords": [
            "Apodization",
            "Axial superresolution",
            "Imaging systems",
            "Optical coherence tomography",
            "Pupil filter"
        ],
        "venue": "Guangxue Xuebao/Acta Optica Sinica",
        "year": 2005,
        "id": "hKW8MaeG"
    },
    "QECmPPGk": {
        "authors": [
            {
                "name": "Qing Ping Tang",
                "org": "Department of Neurology"
            },
            {
                "name": "Qi Dong Yang",
                "org": "Department of Neurology"
            },
            {
                "name": "Ying Hua Wu",
                "org": "Department of Rehabilitation"
            },
            {
                "name": "Gai Qing Wang",
                "org": "Department of Neurology"
            },
            {
                "name": "Zhi Ling Huang",
                "org": "Department of Neurology"
            },
            {
                "name": "Zun Jing Liu",
                "org": "Department of Neurology"
            },
            {
                "name": "Xiao Song Huang",
                "org": "Department of Neurology"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Neurology"
            },
            {
                "name": "Pei Ming Yang",
                "org": "Department of Rehabilitation"
            },
            {
                "name": "Zhen Yong Fan",
                "org": "Department of Rehabilitation"
            }
        ],
        "title": "Effects of problem-oriented willed-movement therapy on motor abilities for people with poststroke cognitive deficits",
        "abstract": "Background and Purpose. Cognitive deficits after stroke are common and interfere with recovery. One purpose of this study was to determine whether the motor abilities of subjects who have poststroke cognitive deficits and who have received problem-oriented willed-movement (POWM) therapy will improve more than the motor abilities of subjects in the reference group who have received neurodevelopmental treatment (NDT). Another purpose of this study was to identify the relationship between cognitive function and motor abilities for both groups. Subjects. The subjects recruited for this study were 36 men and 11 women with various degrees of poststroke cognitive deficits. Methods. A randomized block design was used to assign the subjects to 2 groups. Cognitive function and motor ability were evaluated with the Mini-Mental State Examination and the Stroke Rehabilitation Assessment of Movement (STREAM). Both groups received physical therapy 5 or 6 times per week in 50-minute sessions. Results. The STREAM scores improved after treatment in both groups. Main group effects were found for the lower-extremity (F=4.58, P<.05) and basic mobility (F=27.49, P<.01) subscales of the STREAM. Pretest cognitive function showed a positive relationship with posttest motor ability in the NDT group (r=.446, P<.05). However, the relationship between pretest cognitive function and posttest motor ability had no statistical significance in the POWM group (r=.101, P=.630). Discussion and Conclusion. These findings suggest that, regardless of a person's cognitive function, POWM intervention is effective in improving lower-extremity and basic mobilities and indicates the need to use relatively intact cognitive function or perceptual function, or both, to improve motor rehabilitation for people with cognitive function deficits.",
        "keywords": [
            "Cognitive function",
            "Motor abilities",
            "Perceptual function",
            "Physical therapy",
            "Problem-oriented willed movement",
            "Stroke"
        ],
        "venue": "Physical Therapy",
        "year": 2005,
        "id": "QECmPPGk"
    },
    "IlGvwQQn": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Division of Biotherapy for Cancer"
            },
            {
                "name": "Jia Liu",
                "org": "Cancer Center"
            },
            {
                "name": "Feng Luo",
                "org": "Division of Biotherapy for Cancer"
            }
        ],
        "title": "Serum tumor markers for detection of hepatocellular carcinoma",
        "abstract": "Hepatocellular carcinoma (HCC) is one of the most frequent malignant tumors and is the second most common cause of cancer death in China. Therefore, it is very important to detect this disease and the recurrence at its earlier period. Serum tumor markers, as the effective method for detecting hepatocellular carcinoma for a long time, could be divided into 4 categories: oncofetal antigens and glycoprotein antigens; enzymes and isoenzymes; genes; and cytokines. Serum alpha fetoprotein (AFP) is the most widely used tumor marker in detecting patients with hepatocellular carcinoma, and has been proven to have capability of prefiguring the prognosis. However, it has been indicated that AFP-L3 and DCP excel AFP in differentiating hepatocellular carcinoma from nonmalignant hepatopathy and detecting small hepatocellular carcinoma. Some tumor markers, such as human cervical cancer oncogene and human telomerase reverse transcriptase mRNA, have also been indicated to have higher accuracies than AFR Furthermore, some other tumor markers, such as glypican-3, gamma-glutamyl transferase II, alpha-l-fucosidase, transforming growth factor-beta1, tumor-specific growth factor, have been indicated to be available supplementaries to AFP in the detection. AFP mRNA has been shown to correlate with the metastasis and recurrence of HCC, and it may be the most useful marker to prefigure the prognosis. Some other markers, such as gamma-glutamyl transferase mRNA, vascular endothelial growth factor, and interleukin-8, could also be used as available prognostic indicators, and the simultaneous determination of AFP and these markers may detect the recurrence of HCC at its earlier period. \u00a9 2006 The WJG Press. All rights reserved.",
        "keywords": [
            "Hepatocellular carcinoma",
            "Prognosis",
            "Sensitivity",
            "Serum tumor markers",
            "Specificity"
        ],
        "venue": "World Journal of Gastroenterology",
        "year": 2006,
        "id": "IlGvwQQn"
    },
    "22QcNEeE": {
        "authors": [
            {
                "name": "Xiaofeng Yu",
                "org": "State Key Lab. of Modern Optical Instrumentation"
            },
            {
                "name": "Zhihua Ding",
                "org": "State Key Lab. of Modern Optical Instrumentation"
            },
            {
                "name": "Yuheng Chen",
                "org": "State Key Lab. of Modern Optical Instrumentation"
            },
            {
                "name": "Lina Huang",
                "org": "State Key Lab. of Modern Optical Instrumentation"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Lab. of Modern Optical Instrumentation"
            },
            {
                "name": "Zhenming Zhou",
                "org": "State Key Lab. of Modern Optical Instrumentation"
            },
            {
                "name": "Lan Wu",
                "org": "State Key Lab. of Modern Optical Instrumentation"
            },
            {
                "name": "Xu Liu",
                "org": "State Key Lab. of Modern Optical Instrumentation"
            }
        ],
        "title": "Development of fiber-based optical coherence tomographic imaging system",
        "abstract": "Optical coherence tomography (OCT) is a recently developed high resolution biomedical imaging method, allowing for noninvasive visualizing of internal tissue structure and physiology. It is built that a newly developed single-mode fiber-designed OCT system based on Michelson interferometer and optical heterodyne detection using a broadband near-infrared light source. With this developed system elastic light backscattered from the tissue is picked up, and two-dimensional (2-D) and three-dimensional (3-D) OCT images are reconstructed. Fiber-based OCT system is compact, flexible, and convenient to be combined with fiber catheter, endoscope and other imaging equipments to expand its observing scope and application fields.",
        "keywords": [
            "Fiber-based interferometer",
            "Medical optics and biotechnology",
            "Optical coherence tomography",
            "Three-dimensional reconstruction"
        ],
        "venue": "Guangxue Xuebao/Acta Optica Sinica",
        "year": 2006,
        "id": "22QcNEeE"
    },
    "uLklKJoh": {
        "authors": [
            {
                "name": "Jun Fan",
                "org": "Key Laboratory of Viral Infectious Diseases"
            },
            {
                "name": "Xue-Qin Meng",
                "org": "Organ Transplantation Center"
            },
            {
                "name": "Mei-Fang Yang",
                "org": "Key Laboratory of Viral Infectious Diseases"
            },
            {
                "name": "Lin Zhou",
                "org": "Organ Transplantation Center"
            },
            {
                "name": "Xiao-Ming Chen",
                "org": "Key Laboratory of Viral Infectious Diseases"
            },
            {
                "name": "Min-Jun Hu",
                "org": "Key Laboratory of Viral Infectious Diseases"
            },
            {
                "name": "Wei-Wei Fan",
                "org": "Key Laboratory of Viral Infectious Diseases"
            },
            {
                "name": "Wei-Hang Ma",
                "org": "Key Laboratory of Viral Infectious Diseases"
            },
            {
                "name": "Lan-Juan Li",
                "org": "Key Laboratory of Viral Infectious Diseases"
            }
        ],
        "title": "Association of cytomegalovirus infection with human leukocyte antigen genotypes in recipients after allogeneic liver transplantation",
        "abstract": "Background: Cytomegalovirus (CMV) infection is the important cause affecting the survival rate and function of the transplanted organ after transplantation. The occurrence of CMV infection after liver transplantation (LT) is associated with many factors. Lots of studies suggest that genetic mutation between hosts and CMV may play a role in the occurrence and development of CMV infection. CMV exists in an incubative state, affect or destroy the expression of human leukocyte antigen (HLA) molecules in the host cell surface, and interfere antigen's submission. This mechanism is the key of CMV to avoid immune defense mechanism of the host. To detect HLA and CMV antibody (CMV-Ab), CMV antigen (CMV-Ag) of transplantation recipients, we evaluated the association of CMV infection and the particular HLA genotypes in recipients after LT. Methods: 277 blood samples were collected from 39 LT recipients. CMV antibody and antigen were detected by ELISA or immunohistochemical methods. The HLA types of the recipients were determined by PCR. To analyze the association of HLA alleles and the occurrence of CMV anti-genemia in the patients, relative risk degree (RR) was used as the parameter for the Chi-square test. Results: The LT recipients were serum CMV IgG positive (100%), but none of them was CMV IgM positive (0%). Thirty-three LT recipients (84.6%) were CMV antigenic positive with 1-50 positive leukocytes per 50 000 leukocytes in extent and 7.2 \u00b1 4.2 positive leukocytes per 50 000 leukocytes on average. Thirteen patients developed CMV pneumonia, with CMV antigenic positive (100%) and 17.7 \u00b1 5.5 positive leukocytes per 50 000 leukocytes on average. Some HLA alleles were associated with the occurrence and extent of CMV antigenemia. HLA-A2 was the higher frequency allele for patients with antigenemia (P < 0.05), and 7 patients carrying HLA-DR11 allele developed antigenemia (P < 0.05). In the lower antigenemia group, HLA-A11 was higher in frequency than others (P < 0.05). Besides, none of the patients carrying HLA-B16 allele developed clinical symptoms of CMV infection (P < 0.05). Conclusions: The variability of HLA alleles might modulate immune response to CMV infection. HLA examination before transplantation should be made for prevention and treatment of CMV infection after operation. \u00a9 2006, Hepatobiliary Pancreat Dis Int. All rights reserved.",
        "keywords": [
            "Cytomegalovirus",
            "Cytomegalovirus antigen",
            "Human leukocyte antigen",
            "Liver transplantation"
        ],
        "venue": "Hepatobiliary and Pancreatic Diseases International",
        "year": 2006,
        "id": "uLklKJoh"
    },
    "vvWxBzvV": {
        "authors": [
            {
                "name": "Chun-Ping Wang",
                "org": "Department of Gastroenterology"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Gastroenterology"
            },
            {
                "name": "Shu-Hui Su",
                "org": "Department of Gastroenterology"
            },
            {
                "name": "Yan Chen",
                "org": "Department of Gastroenterology"
            },
            {
                "name": "Yin-Ying Lu",
                "org": "Department of Gastroenterology"
            },
            {
                "name": "Fei Wang",
                "org": "Department of Gastroenterology"
            },
            {
                "name": "Hong-Jun Jia",
                "org": "Department of Gastroenterology"
            },
            {
                "name": "Yong-Yi Feng",
                "org": "Department of Gastroenterology"
            },
            {
                "name": "Yong-Ping Yang",
                "org": "Department of Gastroenterology"
            }
        ],
        "title": "Augmenter of liver regeneration promotes hepatocyte proliferation induced by Kupffer cells",
        "abstract": "Aim: To observe the effects of augmenter of liver regeneration (ALR) on Kupffer cells and to determine whether ALR promotes hepatocyte proliferation induced by Kupffer cells. Methods: Kupffer cells and hepatocytes were cultured in vitro and various concentrations of recombinant rat ALR (rrALR) were added. ",
        "keywords": [
            "Augmenter of liver regeneration",
            "Kupffer cell",
            "Liver regeneration"
        ],
        "venue": "World Journal of Gastroenterology",
        "year": 2006,
        "id": "vvWxBzvV"
    },
    "UwWX7hFp": {
        "authors": [
            {
                "name": "Xiaofeng Yu",
                "org": "State Key Laboratory of Modern Optical Instrumentation"
            },
            {
                "name": "Zhihua Ding",
                "org": "State Key Laboratory of Modern Optical Instrumentation"
            },
            {
                "name": "Yuheng Chen",
                "org": "State Key Laboratory of Modern Optical Instrumentation"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Modern Optical Instrumentation"
            },
            {
                "name": "Zhenming Zhou",
                "org": "State Key Laboratory of Modern Optical Instrumentation"
            },
            {
                "name": "Na Li",
                "org": "State Key Laboratory of Modern Optical Instrumentation"
            },
            {
                "name": "Ling Wang",
                "org": "State Key Laboratory of Modern Optical Instrumentation"
            },
            {
                "name": "Yaliang Yang",
                "org": "State Key Laboratory of Modern Optical Instrumentation"
            }
        ],
        "title": "Functional expansion of optical coherence tomography for Doppler imaging",
        "abstract": "Optical Doppler tomography (ODT) is a non-invasive and non-contact imaging technology which combines Doppler velocimetry with optical coherence tomography (OCT) for measuring blood flow velocity and blood vessel distribution in highly scattering biological tissue. The principle of phase-resolved ODT based on digital Hilbert transformation is described and verified by measuring polystyrene solution flow velocity through glass capillary and microchannels of biochip respectively. With measurement for the Doppler frequency shift of the polystyrene flowing through glass capillary, the curve of the velocity of flow is obtained. The obtained images with high spatial and velocity resolutions, demonstrates that the developed ODT system has promising value for future clinical applications.",
        "keywords": [
            "Digital Hilbert transformation",
            "Doppler frequency shift",
            "Medical optics and biotechnology",
            "Optical Doppler tomography"
        ],
        "venue": "Guangxue Xuebao/Acta Optica Sinica",
        "year": 2006,
        "id": "UwWX7hFp"
    },
    "4tKbyPNz": {
        "authors": [
            {
                "name": "Yu Jiang",
                "org": "State Key Laboratory of Biotherapy"
            },
            {
                "name": "Jun-Ying Li",
                "org": "State Key Laboratory of Biotherapy"
            },
            {
                "name": "Chang Liu",
                "org": "Department of Radiology"
            },
            {
                "name": "Mei-Juan Huang",
                "org": "State Key Laboratory of Biotherapy"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Biotherapy"
            },
            {
                "name": "Mei Li",
                "org": "State Key Laboratory of Biotherapy"
            },
            {
                "name": "Xia Zhao",
                "org": "Department of Gynecology and Obstetrics"
            },
            {
                "name": "Yu-Quan Wei",
                "org": "State Key Laboratory of Biotherapy"
            }
        ],
        "title": "Different attitudes of oncology clinicians toward truth telling of different stages of cancer",
        "abstract": "Objectives: To investigate different attitudes of oncology clinicians toward whether and how to disclose diagnosis to patients with different stages of cancer. Materials and methods: A questionnaire investigating physician's demographic information and attitude toward truth telling was delivered to 256 Chinese oncology clinicians. Results: Two hundred thirty-two (90.6%) physicians completed the questionnaire. Of these oncology clinicians, 87.5% reported that a patient with early-stage cancer should be informed of the diagnosis, while only 40.5% believed that a patient with terminal illness should know the truth (P<0.001). Physicians who preferred to tell the truth reported that patients with early or terminal stage of cancer should be informed by the doctor-in-charge (81.3 vs 77.7%, respectively; P>0.05), immediately after the diagnosis (83.7 vs 87.2%, respectively), and in a quiet and undisturbed room (63.5 vs 68.1%, respectively; P>0.05). In stepwise multiple logistic regression analyses, no demographic information showed association with truth telling of early-stage cancer. Women doctors [odds ratio (OR), 2.25; 95% CI, 1.31 to 3.89; P=0.004] were more likely than men to want the patient to be informed of the terminal illness. Physicians with cancer relatives (OR, 0.55; 95% CI, 0.31 to 0.97; P=0.04) were less likely than physicians without cancer relatives to want the patient to be informed of the terminal illness. Conclusion: Oncology clinicians differed in their attitudes toward truth telling of different stages of cancer. Physicians reported that the doctor-in-charge should be the ones to disclose the condition of the patient, immediately after the diagnosis, and in a quiet and undisturbed room. \u00a9 2006 Springer-Verlag.",
        "keywords": [
            "Disclosure",
            "Early-stage cancer",
            "Oncology clinicians",
            "Terminal illness"
        ],
        "venue": "Supportive Care in Cancer",
        "year": 2006,
        "id": "4tKbyPNz"
    },
    "qqfr09dU": {
        "authors": [
            {
                "name": "Zhi-Liang Yu",
                "org": ""
            },
            {
                "name": "Jiang-Ming Jiang",
                "org": ""
            },
            {
                "name": "Dan-Hong Wu",
                "org": ""
            },
            {
                "name": "Hui-Jun Xie",
                "org": ""
            },
            {
                "name": "Jin-Jin Jiang",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Ling Peng",
                "org": ""
            },
            {
                "name": "Guan-Shui Bao",
                "org": ""
            }
        ],
        "title": "Febrile seizures are associated with mutation of seizure-related (SEZ) 6, a brain-specific gene",
        "abstract": "Genetic factors contribute significantly to the etiology of febrile seizures (FS), the most common type of seizures in childhood. However, in most patients with FS, the causative gene is unknown. The purpose of this study was to explore the relationship between human brain-specific gene SEZ-6 and FS. Through amplification of genomic DNA by PCR and sequencing of the resulting products, we screened 75 subjects for mutations in the coding region (17 exons) of the SEZ-6 gene. Fifteen subjects were healthy individuals and 60 subjects had FS. Patients with FS could be divided into sub-groups based on seizure type (42 simple and 18 complex) and family history (41 had a positive family history). All patients have been followed to date to evaluate seizure recurrence and the development of epilepsy. No mutations were found in healthy controls, but 21 of the patients with FS had mutations in SEZ-6, and the most common type of mutation was a heterozygous, cytosine insertion (frame shift mutation) at position 1435 of the cDNA. The mutation incidence was significantly higher in patients with complex FS (vs. simple FS) and in patients with a positive family history. Sixteen of 42 patients with simple FS experienced seizure recurrence during the 1-5-year follow-up period. Fifteen of 18 patients with complex FS also experienced a recurrence during this period. Among these patients with recurrences, five patients with simple FS and six patients with complex FS have developed epilepsy. The mutation incidence among these epileptic patients is 72.7%. The human SEZ-6 gene is related to the occurrence and development of FS and may be a novel candidate gene for epilepsy. Screening for mutations in SEZ-6 may be valuable in predicting FS recurrence or the development of epilepsy. \u00a9 2006 Wiley-Liss, Inc.",
        "keywords": [
            "Epilepsy",
            "Febrile seizures",
            "Gene sequencing",
            "Polymerase chain reaction",
            "SEZ-6"
        ],
        "venue": "Journal of Neuroscience Research",
        "year": 2007,
        "id": "qqfr09dU"
    },
    "FgmmHQ9e": {
        "authors": [
            {
                "name": "Xiao-Dong Li",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Li-Ming Wu",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Hai-Yang Xie",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Xiao Xu",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Ting-Bo Liang",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Wei-Lin Wang",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Yan Shen",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Min Zhang",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            }
        ],
        "title": "No association exists between E-cadherin gene polymorphism and tumor recurrence in patients with hepatocellular carcinoma after transplantation",
        "abstract": "Background: E-cadherin is an epithelial cell adhesion molecule, and decreased E-cadherin expression in liver cancer is associated with poor prognosis. A -160 C \u2192A polymorphism in the promoter region of E-cadherin has been reported to decrease gene transcription. This allelic variation may be a potential genetic marker for identifying those individuals at higher risk for invasive/metastatic disease. Methods: The effect of E-cadherin gene polymorphism on risk of tumor recurrence was studied in 93 patients with hepatocellular carcinoma (HCC) after liver transplantation, and determined whether this polymorphism is a biomarker for the risk of tumor recurrence. Results: The genotype frequencies in the patients with recurrence were C/C: 0.667, C/A: 0.311, and A/A: 0.022, and in the patients without recurrence C/C: 0.604, C/A: 0.271 and A/A: 0.125. No significant difference was found between the two groups (P=0.171). Between -160 C\u2192A polymorphism and the clinicopathological data, there were no statistically significant differences in the distribution of the parameters as to age, gender, portal vein tumor thrombi, preoperative alpha-fetoprotein level, tumor size, or histopathological grading (P>0.05). Conclusion: The results of this study show no association exists between the E-cadherin genotype and the risk of tumor recurrence in Chinese patients with HCC. \u00a9 2007, Hepatobiliary Pancreat Dis Int. All rights reserved.",
        "keywords": [
            "Carcinoma",
            "E-cadherin",
            "Hepatocellular",
            "Liver transplantation",
            "Single nucleotide polymorphism"
        ],
        "venue": "Hepatobiliary and Pancreatic Diseases International",
        "year": 2007,
        "id": "FgmmHQ9e"
    },
    "4aDeYHNA": {
        "authors": [
            {
                "name": "Yan-Qiang Hou",
                "org": "Department of Clinical Laboratory"
            },
            {
                "name": "Jia-Tao Lou",
                "org": "Department of Laboratory Diagnosis"
            },
            {
                "name": "Liang Peng",
                "org": "Department of Clinical Laboratory"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Laboratory Diagnosis"
            },
            {
                "name": "Jian Ni",
                "org": "Shanghai Fuchun Zhongnan Biotech Company"
            },
            {
                "name": "Xian-Tao Kong",
                "org": "Department of Laboratory Diagnosis"
            },
            {
                "name": "Ren-Qian Zhong",
                "org": "Department of Laboratory Diagnosis"
            }
        ],
        "title": "Detection and clinical significance of ECM1 gene expression in colorectal cancer tissue",
        "abstract": "AIM: To investigate the expression and significance of the ECM1 gene in colorectal cancer tissue. METHODS: Based on TaqMan-MGB methodology, real time quantitative polymerase chain reaction (RQ-PCR) was used to detect the mRNA levels of ECM1 in tissue from normal controls (n = 46), colorectal adenoma (n = 18), colorectal cancer without lymphatic metastasis (n = 25) and colorectal cancer with lymphatic metastasis (n = 21). RESULTS: The mRNA expression of ECM1 in colorectal cancer tissue including those with and without lymphatic metastasis was significantly higher than that in normal and adenoma tissue [(6.89 \u00b1 2.96) \u00d710",
        "keywords": [
            "Colorectal cancer",
            "Extracellular matrix protein 1",
            "Real time quantitative polymerase chain reaction"
        ],
        "venue": "World Chinese Journal of Digestology",
        "year": 2007,
        "id": "4aDeYHNA"
    },
    "QFE8NEIT": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "No. 9 Department of Infectious Diseases"
            },
            {
                "name": "Yong-Ping Yang",
                "org": "No. 9 Department of Infectious Diseases"
            },
            {
                "name": "Chun-Ping Wang",
                "org": "No. 9 Department of Infectious Diseases"
            },
            {
                "name": "Wei Ma",
                "org": "No. 9 Department of Infectious Diseases"
            },
            {
                "name": "Hua-Ming Wang",
                "org": "No. 9 Department of Infectious Diseases"
            },
            {
                "name": "Xue-Mei Ma",
                "org": "No. 9 Department of Infectious Diseases"
            },
            {
                "name": "Yong-Yi Feng",
                "org": "No. 9 Department of Infectious Diseases"
            },
            {
                "name": "Shu-Hui Su",
                "org": "No. 9 Department of Infectious Diseases"
            },
            {
                "name": "Fu-Sheng Wang",
                "org": "No. 9 Department of Infectious Diseases"
            },
            {
                "name": "Lin-Jing An",
                "org": "No. 9 Department of Infectious Diseases"
            },
            {
                "name": "Dong-Ying Qi",
                "org": "No. 9 Department of Infectious Diseases"
            },
            {
                "name": "Yin-Ying Lu",
                "org": "No. 9 Department of Infectious Diseases"
            },
            {
                "name": "Yan Chen",
                "org": "No. 9 Department of Infectious Diseases"
            },
            {
                "name": "Hong-Jun Jia",
                "org": "No. 9 Department of Infectious Diseases"
            }
        ],
        "title": "Hepatitis B related liver failure treated with hepatocyte transplantation: A two-year follow-up",
        "abstract": "Background: Hepatocyte transplantation has attracted more and more attention as a therapeutic measure for liver failure and genetic liver diseases. Objective: To evaluate the efficacy and safety of human hepatocyte transplantation in treating hepatitis B related liver failure in one case by a 2-year follow-up. Design: A case-report of 2-year follow-up. Setting: No.9 Department of Infectious Diseases, Bioengineering Research Room, the 302 Hospital of Chinese PLA. Participant: One inpatient with hepatitis B related liver failure was selected from the 302 Hospital of Chinese PLA, and she was diagnosed according the laboratory tests. The transplanted hepatocytes were originated from the healthy liver of a 24-year-old man, who had signed the protocol for liver donation before death. Methods: The hepatocyte transplantation was completed in the Department of Radiology, the 302 Hospital of Chinese PLA in December 2004. Liver was isolated to obtain human primary hepatocytes, and then cryopreserved. The hepatocytes were transplanted into recipient spleen via femoral vein after resuscitation. The clinical symptoms, changes of blood biochemical indexes, and changes of spleen MRI signals were observed before and after operation. The patient was reexamined every half a year after operation, including liver function, blood coagulation function, B-mode ultrasonography, gastroscopy and MRI, and she was followed up for 2 years. Main Outcome Measures: Liver function, blood coagulation function, imaging indexes, immunological indexes, complication and rejection. Results: 1 Totally (1-2)\u00d710",
        "keywords": [
            ""
        ],
        "venue": "Journal of Clinical Rehabilitative Tissue Engineering Research",
        "year": 2007,
        "id": "QFE8NEIT"
    },
    "rGGkzS4h": {
        "authors": [
            {
                "name": "Wei-Lin Wang",
                "org": "Key Lab. of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Guo-Liang Zhang",
                "org": "Key Lab. of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Li-Hua Wu",
                "org": "Key Lab. of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Min-Ya Yao",
                "org": "Key Lab. of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Jing Jin",
                "org": "Key Lab. of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Chang-Ku Jia",
                "org": "Key Lab. of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Hai-Yang Xie",
                "org": "Key Lab. of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Lab. of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Zhi-Jun Jiang",
                "org": "Key Lab. of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Key Lab. of Combined Multi-Organ Transplantation"
            }
        ],
        "title": "Efficacy of hepatitis B immunoglobulin in relation to the gene polymorphisms of human leukocyte Fc\u03b3 receptor III (CD16) in Chinese liver transplant patients",
        "abstract": "Background: Although the use of hepatitis B immunoglobulin (HBIG) may lead to a significant reduction in recurrent hepatitis B virus (HBV) infection and improve the survival of patients who have undergone liver transplantation (LT) for hepatitis B-related diseases, the recurrence of the disease still remains at a lower level. Different clinical curative effects were observed in patients with the same HBV-related diseases and the same therapy. This study was undertaken to investigate whether the efficacy of HBIG is associated with FCGR3A gene polymorphisms in Chinese liver transplant patients. Methods: Altogether 77 patients who had received liver transplantation for hepatitis B-related diseases with more than one-year survival after surgery were studied. The recurrence of HBV was characterized by the appearance of HBsAg in serum after the operation. The FCGR3A genotyping was performed using genomic DNA sequencing (ABI 3037). Single nucleotide polymorphism at nucleotide 559 was detected by Polyphred. Results: Of the 77 patients, 14 were complicated with HBV recurrence post-transplant. The FCGR3A at nucleotide 559 TT was observed in 35 (45.5%) subjects, whereas TG in 31(40.3%) and GG in 11(14.3%). In the 559G carrier group (n=42, 54.5%), the risk of HBV recurrence was 9.5%, and 1- and 2-year recurrence-free survival rates were 95.2% and 88.7%, respectively. In the 559G noncarrier group (n=35, 45.5%), the risk of HBV recurrence was 28.6%, and 1- and 2-year recurrence-free survival rates were 74.3% and 69.3%, respectively. The risk of HBV recurrence and the recurrence-free survival rate were both statistically different between the 559G carrier and noncarrier groups (P<0.05). Conclusions: A single nucleotide polymorphism (T/G) at position 559 of the FCGR3A gene was found in Chinese patients. The efficacy of HBIG in prophylaxis of HBV recurrence after LT is associated with the gene polymorphism, so detecting FCGR3A genotypes can be a clinical reference of the HBIG administration.",
        "keywords": [
            "Fc gamma RIII",
            "Hepatitis B",
            "Immunoglobulin",
            "Polymorphism",
            "Recurrence"
        ],
        "venue": "Chinese Medical Journal",
        "year": 2007,
        "id": "rGGkzS4h"
    },
    "cp0qLaW6": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Department of Dermatology"
            },
            {
                "name": "Yan-Qun Liu",
                "org": "Department of Dermatology"
            },
            {
                "name": "Zhi-Ping Wei",
                "org": "Department of Dermatology"
            }
        ],
        "title": "Effect of curcumin on the MT1-MMP-mediated promatrix metalloproteinase-2 activation of the tumor-bearing mice",
        "abstract": "Objective: To investigate the effect of curcumin on the inhibition of mouse melanoma, the expression of MT1-MMP and the activation of MMP-2 and explore the possible mechanism of curcumin for anti-tumor as well as novel strategy for malignant melanoma. Methods: Melanoma cell line B16 was injected hypodermically into the outside of mouse right thigh to establish a model of tumor-bearing mice. Then curcumin was injected intraperitoneally and the size of tumor volume was observed in various groups. The tumor MMP-2 activity and MT1-MMP mRNA expression were detected by Western blotting and reverse transcription polymerase chain reaction (RT-PCR) respectively. Results: The size and the weight of tumor were decreased in the therapeutic group than those of the control group. Especially in the group treated with 50 mg/kg curcumin, the tumor size and weight decreased 55.61% and 55.56% respectively. Compared with the control, the level of MMP-2 activity decreased 50.94% (50 mg/kg group) and 45.75% (100 mg/kg group); MT1-MMP mRNA decreased about 52.85% (50 mg/kg group) and 48.73% (100 mg/kg group) after curcumin treatment. There was a positive correlation between the tumor MMP-2 activity and MT1-MMP mRNA level. Conclusions: Curcumin can inhibit the growth of malignant melanoma. The inhibiting effectiveness may be due to suppressed MMP-2 activity by reducing MT1-MMP mRNA expression.",
        "keywords": [
            "Curcumin",
            "Gene",
            "Gene, MMP-2",
            "Malignant",
            "Melanoma",
            "MT1-MMP"
        ],
        "venue": "Journal of Clinical Dermatology",
        "year": 2007,
        "id": "cp0qLaW6"
    },
    "oHZm8avb": {
        "authors": [
            {
                "name": "Sheng Yan",
                "org": ""
            },
            {
                "name": "Qiyi Zhang",
                "org": ""
            },
            {
                "name": "Minxia Cai",
                "org": ""
            },
            {
                "name": "Da Yu",
                "org": ""
            },
            {
                "name": "Jie Chen",
                "org": ""
            },
            {
                "name": "Pengfei Yu",
                "org": ""
            },
            {
                "name": "Qiyu Zhao",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Matthias Hoffmann",
                "org": ""
            },
            {
                "name": "Shusen Zheng",
                "org": ""
            }
        ],
        "title": "A novel model of portal vein transplantation in mice using two-cuff technique",
        "abstract": "Allogeneic portal vein (PV) grafts have been widely used for vascular reconstruction in the aggressive biliary-pancreatic surgery and partial liver transplantation. We developed a novel PV transplantation model aimed at studying the pathologic alteration of the grafts and further managements. The PV graft was implanted orthotopically into the recipient using two-cuff technique. A total of 80 PV transplants have been performed, and the overall survival rate for the recipients was 91.3% (73/80). Mice were randomly separated into isografts group, allografts group, and allografts group treated with CTLA4-Ig. PV grafts were harvested on the 1st, 2nd, 4th, and 8th postoperative week. The isografts remained intact vascular structure, and the allografts developed marked rejection with significant increase in wall thickness (95 \u00b1 19 \u03bcm vs. 49 \u00b1 7 \u03bcm P < 0.01) and decrease in lumen area (1.9 \u00b1 1.1 \u00d7 10",
        "keywords": [
            ""
        ],
        "venue": "Microsurgery",
        "year": 2007,
        "id": "oHZm8avb"
    },
    "LUK6o7hF": {
        "authors": [
            {
                "name": "Zhijun Jiang",
                "org": ""
            },
            {
                "name": "Xiaoning Feng",
                "org": ""
            },
            {
                "name": "Wu Zhang",
                "org": ""
            },
            {
                "name": "Feng Gao",
                "org": ""
            },
            {
                "name": "Qi Ling",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Haiyang Xie",
                "org": ""
            },
            {
                "name": "Qixing Chen",
                "org": ""
            },
            {
                "name": "Shusen Zheng",
                "org": ""
            }
        ],
        "title": "Recipient cytotoxic T lymphocyte antigen-4 +49 G/G genotype is associated with reduced incidence of hepatitis B virus recurrence after liver transplantation among Chinese patients",
        "abstract": "Background: Single-nucleotide polymorphisms (SNP) of two-gene locus cytotoxic T lymphocyte antigen-4 (CTLA-4) +49 and CD86 +1057 were previously reported to influence the outcome of liver transplantation (LT) with respect to allograft acceptance. SNP at CTLA-4 + 49 was also suggested to be associated with the individual difference in the clearance of hepatitis B virus (HBV). However, their influence on the incidence of post-LT HBV reinfection was not clear. With the increasing knowledge of costimulatory mechanisms on LT and host immune response, we designed this study to investigate the relationship between different alleles as well as genotypes at these two locations and HBV reinfection after LT. Methods: Genomic DNA from 167 LT recipients with HBV-related diseases was genotyped for CTLA-4 +49 and CD86 +1057 genomic polymorphisms using a sequence-specific primer-polymerase chain reaction (PCR-SSP). HBV recurrence was diagnosed based on the serological and pathological finding of HBV DNA and HBsAg. Results: The present study indicated that the recipients with CTLA-4 +49 GG genotype had a reduced risk (6.67%) of HBV recurrence compared with non-CTLA-4 +49 GG-carrying individuals (20.7%) (relative risk 3.098) (P = 0.032). The allelic frequency of CTLA-4 +49 G was also significantly lower in patients with HBV recurrence, compared with that in patients without HBV recurrence (P = 0.013, odds ratio 2.176, 95% confidence interval 1.170-4.046). However, no significant association was found between CD86 +1057 and HBV recurrence. Conclusion: Our result on CTLA-4+49 A/G polymorphism indicated that the CTLA-4 +49 GG genotype was related to a reduced risk in the incidence of HBV recurrence. \u00a9 2007 Blackwell Munksgaard.",
        "keywords": [
            "CTLA-4",
            "HBV recurrence",
            "Liver transplantation",
            "SNP"
        ],
        "venue": "Liver International",
        "year": 2007,
        "id": "LUK6o7hF"
    },
    "q7eIkpnL": {
        "authors": [
            {
                "name": "Yan Chen",
                "org": "Department of Gastroenterology"
            },
            {
                "name": "Chun-Ping Wang",
                "org": "Department of Gastroenterology"
            },
            {
                "name": "Yin-Ying Lu",
                "org": "Department of Gastroenterology"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Gastroenterology"
            },
            {
                "name": "Shu-Hui Su",
                "org": "Department of Gastroenterology"
            },
            {
                "name": "Hong-Jun Jia",
                "org": "Department of Gastroenterology"
            },
            {
                "name": "Yong-Yi Feng",
                "org": "Department of Gastroenterology"
            },
            {
                "name": "Yong-Ping Yang",
                "org": "Department of Gastroenterology"
            }
        ],
        "title": "Hepatic stellate cells may be potential effectors of platelet activating factor induced portal hypertension",
        "abstract": "Aim: To determine platelet activating factor (PAF) receptor expression in cirrhotic hepatic stellate cells. Methods: Hepatic stellate cells, isolated from the livers of control and CCI",
        "keywords": [
            "Cirrhosis",
            "Hepatic stellate cells",
            "Kupffer cells",
            "Platelet activating factor",
            "Receptor"
        ],
        "venue": "World Journal of Gastroenterology",
        "year": 2008,
        "id": "q7eIkpnL"
    },
    "ApdgKDG9": {
        "authors": [
            {
                "name": "Yu-Ling Sun",
                "org": ""
            },
            {
                "name": "Sheng-Yong Yin",
                "org": ""
            },
            {
                "name": "Hai-Yang Xie",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Fei Xue",
                "org": ""
            },
            {
                "name": "Li-Ming Wu",
                "org": ""
            },
            {
                "name": "Feng Gao",
                "org": ""
            },
            {
                "name": "Shu-Sen Zheng",
                "org": ""
            }
        ],
        "title": "Stem-like cells in hepatitis B virus-associated cirrhotic livers and adjacent tissue to hepatocellular carcinomas possess the capacity of tumorigenicity",
        "abstract": "Background and Aim: Recent investigations demonstrate that adult stem cells may be targets for malignant transformation and that the stem-like cells in diseased livers possess the capacity of tumorigenicity in animal models. The aim of this study is to examine expression patterns of stem-cell markers in hepatitis B virus-associated cirrhotic livers and hepatocellular carcinomas (HCC), and to investigate the stem-like cell capacity of tumorigenicity in these tissues. Methods: Twenty surgically resected HCCs and corresponding adjacent tissues as well as 10 cirrhotic liver tissues were collected and immunohistochemical staining were performed to detect the expression of CD34, Thy-1, CD133, and c-kit. Then the non-cancerous tissues were transplanted into immunodeficient mice and the characteristics of the cells from primary tissue cultures were explored in vitro. Results: Immunohistochemical analysis characterized different expression patterns of stem-cell markers among these tissues. First, CD34 and Thy-1 expression was identified in proliferating bile ductules and it represented hepatic progenitor cells; CD133 and c-kit-positive cells were observed in the parenchyma of these tissues, and some of them were characterized as intermediate hepatocytes morphologically and spatially. Second, in two groups including three mice transplanted with tissues adjacent to HCC-initiated tumors, CD133 and c-kit expression was detected. Finally, our study also indicated that stem-like cells from tissue could express hepatic-lineage markers and possessed great capacities to proliferate, self-renew, and form clones in vitro. Conclusion: Our results suggest that the stem-like cells in cirrhotic livers possess the capacity of tumorigenicity and may contain candidates for HCC cancer stem cells. \u00a9 2008 The Authors.",
        "keywords": [
            "Hepatitis B virus",
            "Hepatocellular carcinoma",
            "Stem cells",
            "Tumorigenicity"
        ],
        "venue": "Journal of Gastroenterology and Hepatology (Australia)",
        "year": 2008,
        "id": "ApdgKDG9"
    },
    "pzjnQ2NI": {
        "authors": [
            {
                "name": "Mei-juan Huang",
                "org": "State Key Laboratory of Biotherapy"
            },
            {
                "name": "Yu Jiang",
                "org": "State Key Laboratory of Biotherapy"
            },
            {
                "name": "Wei-ping Liu",
                "org": "Department of Pathology"
            },
            {
                "name": "Zhi-ping Li",
                "org": "Department of Radiotherapy for Cancer"
            },
            {
                "name": "Mei Li",
                "org": "Department of Biotherapy for Cancer"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Biotherapy for Cancer"
            },
            {
                "name": "Yong Xu",
                "org": "Department of Radiotherapy for Cancer"
            },
            {
                "name": "Chun-hua Yu",
                "org": "Department of Biotherapy for Cancer"
            },
            {
                "name": "Qiu Li",
                "org": "State Key Laboratory of Biotherapy"
            },
            {
                "name": "Feng Peng",
                "org": "State Key Laboratory of Biotherapy"
            },
            {
                "name": "Ji-Yan Liu",
                "org": "State Key Laboratory of Biotherapy"
            },
            {
                "name": "Feng Luo",
                "org": "State Key Laboratory of Biotherapy"
            },
            {
                "name": "You Lu",
                "org": "State Key Laboratory of Biotherapy"
            }
        ],
        "title": "Early or Up-Front Radiotherapy Improved Survival of Localized Extranodal NK/T-Cell Lymphoma, Nasal-Type in the Upper Aerodigestive Tract",
        "abstract": "Purpose: To investigate the role of early or up-front radiotherapy (RT), the optimal RT dose required to achieve appropriate treatment outcome and prognostic factors for patients with localized extranodal NK/T-cell lymphoma, nasal-type, in the upper aerodigestive tract. Methods and Materials: Eighty-two patients were reviewed. Eight patients were treated with chemotherapy (CT) alone, 9 patients received RT alone, and 65 patients were given combined modality treatment of CT and RT (CMT). Of those 74 patients receiving RT, 31 patients were given up-front RT, whereas CT was the initial therapy for 43 patients and 41 of those 43 patients received early RT. Results: Five-year overall survival (OS) and disease-free survival (DFS) were 52.3% and 39.2%, respectively. RT was the only independent prognostic factor for both OS and DFS at both the univariate and multivariate level. The 5-year OS and DFS were better in patients receiving \u226554 Gy of RT as compared with that of <54 Gy (5-year OS 75.5% vs. 46.1%, p = 0.019; 5-year DFS 60.3% vs. 33.4%, p = 0.004). Up-front RT presented better survival in Stage I patients when compared with that of initial CT followed by early RT (5-year OS 90.0% vs. 48.9%, p = 0.012; 5-year DFS 78.7% vs. 39.9%, p = 0.021). Conclusion: Early or up-front RT had an essential role in improved OS and DFS in patients with localized extranodal NK/T-cell lymphoma, nasal-type, in the upper aerodigestive tract. The recommended tumor dose was at least 54 Gy. Up-front RT may yield more benefits on survival in patients with Stage I disease. \u00a9 2008 Elsevier Inc. All rights reserved.",
        "keywords": [
            "Chemotherapy",
            "Early or up-front radiotherapy",
            "Extranodal NK/T-cell lymphoma",
            "Retrospective analysis",
            "Upper aerodigestive tract"
        ],
        "venue": "International Journal of Radiation Oncology Biology Physics",
        "year": 2008,
        "id": "pzjnQ2NI"
    },
    "gyXRi9Nh": {
        "authors": [
            {
                "name": "Yin-Ying Lu",
                "org": "Department of Gastroenterology"
            },
            {
                "name": "Chun-Ping Wang",
                "org": "Department of Gastroenterology"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Gastroenterology"
            },
            {
                "name": "Yan Chen",
                "org": "Department of Gastroenterology"
            },
            {
                "name": "Shu-Hui Su",
                "org": "Department of Gastroenterology"
            },
            {
                "name": "Yong-Yi Feng",
                "org": "Department of Gastroenterology"
            },
            {
                "name": "Yong-Ping Yang",
                "org": "Department of Gastroenterology"
            }
        ],
        "title": "Synthesis of platelet-activating factor and its receptor expression in Kupffer cells in rat carbon tetrachloride-induced cirrhosis",
        "abstract": "Aim: To determine the platelet-activating factor (PAF) synthesis and its receptor expression in Kupffer cells in rat carbon tetrachloride-induced cirrhosis. Methods: Kupffer cells, isolated from the livers of control and CCl",
        "keywords": [
            "Cirrhosis",
            "Kupffer cells",
            "Platelet activating factor",
            "Receptor"
        ],
        "venue": "World Journal of Gastroenterology",
        "year": 2008,
        "id": "gyXRi9Nh"
    },
    "1iz8dzUM": {
        "authors": [
            {
                "name": "Jie Meng",
                "org": "State Key Laboratory of Modern Optical Instrumentation"
            },
            {
                "name": "Zhi-Hua Ding",
                "org": "State Key Laboratory of Modern Optical Instrumentation"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Modern Optical Instrumentation"
            }
        ],
        "title": "Axial superresolution in optical coherence tomography",
        "abstract": "Optical superresolution is adopted for axial resolution enhancement in optical coherence tomography (OCT). Three-zone phase and amplitude pupil filters were designed and implemented in the sample arm of OCT system. Axial response curves measured under different conditions are in good agreement with the theoretical analyses. Comparison results achieve an improvement of more than 10%, demonstrating the feasibility of axial superresolution in OCT by use of appropriate pupil filters.",
        "keywords": [
            "Axial superresolution",
            "Optical coherence tomography",
            "Pupil filter"
        ],
        "venue": "Guangzi Xuebao/Acta Photonica Sinica",
        "year": 2008,
        "id": "1iz8dzUM"
    },
    "Eydrx6Ka": {
        "authors": [
            {
                "name": "Xing Li",
                "org": "Key Laboratory of Green Chemistry and Technology (Sichuan University)"
            },
            {
                "name": "Xiaohua Liu",
                "org": "Key Laboratory of Green Chemistry and Technology (Sichuan University)"
            },
            {
                "name": "Yingzi Fu",
                "org": "Key Laboratory of Green Chemistry and Technology (Sichuan University)"
            },
            {
                "name": "Lijia Wang",
                "org": "Key Laboratory of Green Chemistry and Technology (Sichuan University)"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Green Chemistry and Technology (Sichuan University)"
            },
            {
                "name": "Xiaoming Feng",
                "org": "State Key Laboratory of Oral Diseases"
            }
        ],
        "title": "Direct allylation of aldimines catalyzed by C2-symmetric N,N\u2032-dioxide-ScIII complexes: Highly enantioselective synthesis of homoallylic amines",
        "abstract": "A study was conducted for catalytic asymmetric direct allylation of aldimines accelerated by C",
        "keywords": [
            "Aldimines",
            "Allylation",
            "Amines",
            "Asymmetric catalysis"
        ],
        "venue": "Chemistry - A European Journal",
        "year": 2008,
        "id": "Eydrx6Ka"
    },
    "RXH3Tb9d": {
        "authors": [
            {
                "name": "Zhen Li",
                "org": "Department of Cardiology"
            },
            {
                "name": "Changqing Yu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Yu Han",
                "org": "Department of Cardiology"
            },
            {
                "name": "Hongmei Ren",
                "org": "Department of Cardiology"
            },
            {
                "name": "Weibin Shi",
                "org": "Department of Cardiology"
            },
            {
                "name": "Chunjiang Fu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Duofen He",
                "org": "Department of Cardiology"
            },
            {
                "name": "Lan Huang",
                "org": "Xinqiao Hospital"
            },
            {
                "name": "Chengming Yang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xukai Wang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Cardiology"
            },
            {
                "name": "Laureano D. Asico",
                "org": "Department of Pediatrics"
            },
            {
                "name": "Chunyu Zeng",
                "org": "Dept. of Cardiology"
            },
            {
                "name": "Pedro A. Jose",
                "org": "Department of Physiology and Biophysics"
            }
        ],
        "title": "Inhibitory effect of D",
        "abstract": "The sympathetic nervous system plays an important role in the regulation of blood pressure. There is increasing evidence for positive and negative interactions between dopamine and adrenergic receptors; the activation of the \u03b1-adrenergic receptor induces vasoconstriction, whereas the activation of dopamine receptor induces vasorelaxation. We hypothesize that the D ",
        "keywords": [
            "\u03b11-adrenergic receptor",
            "Hypertension"
        ],
        "venue": "American Journal of Physiology - Heart and Circulatory Physiology",
        "year": 2008,
        "id": "RXH3Tb9d"
    },
    "jbh1vprF": {
        "authors": [
            {
                "name": "Hao Liang",
                "org": "Department of Epidemiology"
            },
            {
                "name": "Xu Wang",
                "org": "Children's Hospital of Philadelphia"
            },
            {
                "name": "Hui Chen",
                "org": "First Affiliated Hospital"
            },
            {
                "name": "Li Song",
                "org": "Children's Hospital of Philadelphia"
            },
            {
                "name": "Li Ye",
                "org": "Children's Hospital of Philadelphia"
            },
            {
                "name": "Shi-Hong Wang",
                "org": "Renmin Hospital"
            },
            {
                "name": "Yan-Jian Wang",
                "org": "Children's Hospital of Philadelphia"
            },
            {
                "name": "Lin Zhou",
                "org": "Tongji Medical College"
            },
            {
                "name": "Wen-Zhe Ho",
                "org": "Children's Hospital of Philadelphia"
            }
        ],
        "title": "Methamphetamine enhances HIV infection of macrophages",
        "abstract": "Epidemiological studies have demonstrated that the use of methamphetamine (meth), a sympathomimetic stimulant, is particularly common among patients infected with HIV. However, there is a lack of direct evidence that meth promotes HIV infection of target cells. This study examined whether meth is able to enhance HIV infection of macrophages, the primary target site for the virus. Meth treatment resulted in a significant and dose-dependent increase of HIV reverse transcriptase activity in human blood monocyte-derived macrophages. Dopamine D1 receptor antagonists (SCH23390 and SKF83566) blocked this meth-mediated increase in the HIV infectivity of macrophages. Investigation of the underlying mechanisms of meth action showed that meth up-regulated the expression of the HIV entry co-receptor CCR5 on macrophages. Additionally, meth inhibited the expression of endogenous interferon-\u03b1 and signal transducer and activator of transcription-1 in macrophages. These findings provide direct in vitro evidence to support the possibility that meth may function as a cofactor in the immunopathogenesis of HIV infection and may lead to the future development of innate immunity-based intervention for meth users with HIV infection. Copyright \u00a9 American Society for Investigative Pathology.",
        "keywords": [
            ""
        ],
        "venue": "American Journal of Pathology",
        "year": 2008,
        "id": "jbh1vprF"
    },
    "6xZIDSX1": {
        "authors": [
            {
                "name": "Ying Zhang",
                "org": "Key Laboratory of Infectious Diseases"
            },
            {
                "name": "Hao Chen",
                "org": "Key Laboratory of Combined Multiorgan Transplantation"
            },
            {
                "name": "Yu-Min Li",
                "org": "Lanzhou University"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Key Laboratory of Combined Multiorgan Transplantation"
            },
            {
                "name": "Ya-Gang Chen",
                "org": "Key Laboratory of Infectious Diseases"
            },
            {
                "name": "Lan-Juan Li",
                "org": "Key Laboratory of Infectious Diseases"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Combined Multiorgan Transplantation"
            },
            {
                "name": "Hai-Yang Xie",
                "org": "Key Laboratory of Combined Multiorgan Transplantation"
            },
            {
                "name": "Raaj Kumar Praseedom",
                "org": "Addenbrookes Hospital"
            }
        ],
        "title": "Thymosin \u03b1",
        "abstract": "Objective. The aim of this study was to evaluate the potential efficacy of therapy with thymosin \u03b1",
        "keywords": [
            ""
        ],
        "venue": "Journal of Infectious Diseases",
        "year": 2008,
        "id": "6xZIDSX1"
    },
    "BSil3nQj": {
        "authors": [
            {
                "name": "Yigang Qian",
                "org": "Department of Hepatobiliary Pancreatic Surgery"
            },
            {
                "name": "Junfang Deng",
                "org": "Department of Hepatobiliary Pancreatic Surgery"
            },
            {
                "name": "Lei Geng",
                "org": "Department of Hepatobiliary Pancreatic Surgery"
            },
            {
                "name": "Haiyang Xie",
                "org": "Department of Hepatobiliary Pancreatic Surgery"
            },
            {
                "name": "Guoping Jiang",
                "org": "Department of Hepatobiliary Pancreatic Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Hepatobiliary Pancreatic Surgery"
            },
            {
                "name": "Yan Wang",
                "org": "Department of Hepatobiliary Pancreatic Surgery"
            },
            {
                "name": "Shenyong Yin",
                "org": "Department of Hepatobiliary Pancreatic Surgery"
            },
            {
                "name": "Xiaowen Feng",
                "org": "Department of Hepatobiliary Pancreatic Surgery"
            },
            {
                "name": "Junwei Liu",
                "org": "Department of Hepatobiliary Pancreatic Surgery"
            },
            {
                "name": "Zhou Ye",
                "org": "Department of Hepatobiliary Pancreatic Surgery"
            },
            {
                "name": "Shusen Zheng",
                "org": "Department of Hepatobiliary Pancreatic Surgery"
            }
        ],
        "title": "TLR4 signaling induces B7-H1 expression through MAPK pathways in bladder cancer cells",
        "abstract": "TLR4 (Toll-like receptor 4) and B7-H1, which were known to be restricted to immune cells in the past, were found to be aberrantly expressed in a majority of tumor cells, facilitating tumor evasion from immune surveillance. Our study demonstrated that activation of TLR4 signaling in bladder cancer cells up-regulated B7-H1 expression. Furthermore, this regulation was significantly attenuated by ERK or JNK inhibitor. Our results elucidated the molecule mechanism of regulation of B7-H1 expression through TLR4 signaling and may suggest new strategies of down-regulating the cancer-associated B7-H1 expression for bladder cancer treatment. Copyright \u00a9 Informa Healthcare USA, Inc.",
        "keywords": [
            "B7-H1",
            "Bladder cancer",
            "MAPK",
            "TLR4"
        ],
        "venue": "Cancer Investigation",
        "year": 2008,
        "id": "BSil3nQj"
    },
    "RftYJEZC": {
        "authors": [
            {
                "name": "Junfang Deng",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Yigang Qian",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Lei Geng",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Jie Chen",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Xiaohui Wang",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Haiyang Xie",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Sheng Yan",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Guoping Jiang",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Shusen Zheng",
                "org": "Key Laboratory of Organ Transplantation"
            }
        ],
        "title": "Involvement of p38 mitogen-activated protein kinase pathway in honokiol-induced apoptosis in a human hepatoma cell line (hepG2)",
        "abstract": "Background: Honokiol has been known to have antitumour activity. This study was conducted to evaluate the antiproliferative potential of honokiol against the hepG2 heptocellular cell line and its mechanism of action. Methods: hepG2 cells were treated with honokiol of 0-40 \u03bcg/ml concentration. The cytotoxic effect of honokiol was determined by a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. The apoptosis was evaluated by flow cytometry. Western blots were used to analyse the expression of various proteins (procaspase-9, procaspase-3, cleaved caspase-3, cytochrome c, Bcl-2, Bax, Bad, Bcl-X L and p38). Results: Honokiol induced apoptosis with a decreased expression of procaspase-3 and -9 and an increased expression of active caspase-3. Exposure of hepG2 cells to honokiol resulted in the downregulation of Bcl-X L and Bcl-2 expression and the release of mitochondrial cytochrome c to the cytosol. In addition, honokiol activated the p38 mitogen-activated protein kinase (MAPK) pathway, and the inhibition of this pathway by SB203580 reduced honokiol-induced apoptosis and activation of caspase-3. Conclusion: Honokiol induces apoptosis of hepG2 human hepatocellular carcinoma cells through activation of the p38 MAPK pathway, and, in turn, activation of caspase-3. \u00a9 Journal compilation \u00a9 2008 Blackwell Munksgaard.",
        "keywords": [
            "Apoptosis",
            "Bcl-2",
            "Bcl-XL",
            "Caspase",
            "Cytochromec",
            "hepG2",
            "Honokiol",
            "p38"
        ],
        "venue": "Liver International",
        "year": 2008,
        "id": "RftYJEZC"
    },
    "7k8MbddO": {
        "authors": [
            {
                "name": "Mang-Li Zhang",
                "org": ""
            },
            {
                "name": "Sen Lu",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Shu-Sen Zheng",
                "org": ""
            }
        ],
        "title": "Correlation between ECT2 gene expression and methylation change of ECT2 promoter region in pancreatic cancer",
        "abstract": "Background: Pancreatic cancer is closely related to epigenetic abnormality. The epithelial cell transforming sequence 2 gene (ECT2) plays a critical role in Rho activation during cytokinesis, and thus may play a role in the pathogenesis of pancreatic cancer. In this study, we investigated the relationships between aberrant expression and epigenetic changes of the ECT2 gene in pancreatic cancer. Methods: Four cell lines (PANC-1, Co1o357, T3M-4 and PancTu I) and pancreatic ductal adenocarcinoma (PDAC) tissues were used for mRNA detection. After restriction isoschizomer endonucleases (Msp I/Hpa II) were used to digest the DNA sequence (5\u2032-CCGG-3\u2032), PCR was made to amplify the product. And RT-PCR was applied to determine the expression of the gene. Results: The mRNA expression of the ECT2 gene was higher in pancreatic tumor tissue than in normal tissue. The gene was also expressed in the 4 PDAC cell lines. The methylation states of the upstream regions of the ECT2 gene were almost identical in normal, tumor pancreatic tissues, and the 4 PDAC cell lines. Some of the 5\u2032-CCGG-3\u2032 areas in the upstream region of ECT2 were methylated, while others were unmethylated. Conclusions: The oncogene ECT2 is overexpressed in pancreatic tumor tissues as verified by RT-PCR detection. The methylation status of DNA in promoter areas is involved in the gene expression, along with other factors, in pancreatic cancer. \u00a9 2008, Hepatobiliary Pancreat Dis Int. All rights reserved.",
        "keywords": [
            "Epigenesis, genetic",
            "Epithelial cell transforming sequence 2 gene",
            "Pancreatic neoplasms"
        ],
        "venue": "Hepatobiliary and Pancreatic Diseases International",
        "year": 2008,
        "id": "7k8MbddO"
    },
    "jafVGKRN": {
        "authors": [
            {
                "name": "Hao Zhang",
                "org": "Department of Food Science"
            },
            {
                "name": "Yu-Xiang Ma",
                "org": "College of Grain and Food"
            },
            {
                "name": "Lin Zhou",
                "org": "College of Plant Protection"
            },
            {
                "name": "Hai-Zhen Mo",
                "org": "Department of Food Science"
            }
        ],
        "title": "4-(4-Nitro-benzene-sulfonamido)pyri-dinium chloride",
        "abstract": "In the title compound, C11H10N3O4S",
        "keywords": [
            ""
        ],
        "venue": "Acta Crystallographica Section E: Structure Reports Online",
        "year": 2008,
        "id": "jafVGKRN"
    },
    "jOAUf7SF": {
        "authors": [
            {
                "name": "De-Ren Hou",
                "org": "Department of Neurology"
            },
            {
                "name": "Yan Wang",
                "org": "Department of Neurology"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Neurology"
            },
            {
                "name": "Kun Chen",
                "org": "Department of Neurology"
            },
            {
                "name": "Yi Tian",
                "org": "Department of Neurology"
            },
            {
                "name": "Zhi Song",
                "org": "Department of Neurology"
            },
            {
                "name": "Juan Bao",
                "org": "Department of Neurology"
            },
            {
                "name": "Qi-Dong Yang",
                "org": "Department of Neurology"
            }
        ],
        "title": "Alterd angiotensin-converting enzyme and its effects on the brain in a rat model of Alzheimer disease",
        "abstract": "Background: Alzheimer disease (AD) is a neurodegenerative disease related to aging. At present, its pathological mechanisms remain unclear. Family members of the renin-angiotensin system (RAS) play a role in neuronal plasticity, as well as formation of learning and memory. In this study, we explore the effects of altered angiotensin-converting enzyme (ACE), and investigate the possible mechanisms of perindopril, an ACE inhibitor, on brain structure and function in a rat model of AD, as well as the role that ACE plays in AD. Methods: Sixty Sprague-Dawley rats were selected and randomly divided into 3 groups: control, AD, and perindopril. Each group consisted of 20 rats, with 10 rats for determining pathology, and the remaining 10 rats for quantifying ACE activity. The rat AD model was established by stereotactically injecting amyloid beta protein (A-beta) 1-42 into the right hippocampus. Learning and memory functions were tested using the Y-type electric maze. The number and morphology of abnormal neurons were determined by haematoxylin and eosin staining. Amyloid deposition was measured by Congo red staining. Finally, ACE activity was estimated by spectrophotometry. Results: Compared with the control group, the number of times needed to escape electrical stimuli increased (23.70\u00b13.13, P <0.001), the number of normal neurons in the CA1 region was reduced (density of 96.5\u00b132.6/mm, P <0.001), amyloid deposition was obvious, and ACE activity increased ((34.4\u00b16.6) nmolg",
        "keywords": [
            "Alzheimer disease",
            "Amyloid beta-protein",
            "Angiotensin-converting enzyme",
            "Perindopril"
        ],
        "venue": "Chinese Medical Journal",
        "year": 2008,
        "id": "jOAUf7SF"
    },
    "bwisKzaf": {
        "authors": [
            {
                "name": "Juan Bao",
                "org": "Second Affiliated Hospital"
            },
            {
                "name": "Qi-Dong Yang",
                "org": "Department of Neurology"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Neurology"
            },
            {
                "name": "Hong-Bo Luo",
                "org": "Department of Neurology"
            }
        ],
        "title": "Study of neuronal apoptosis and changes in expression of the proteins related to the mitochondrial pathway after A\u03b21-42 injection in the rat hippocampus",
        "abstract": "The objective was to study neuronal apoptosis and changes in the proteins related to the mitochondrial pathway in the hippocampus of a rat model of Alzheimer's disease (AD) and discuss its significance in AD. Thirty-six Sprague-Dawley rats were divided into 3 groups: a normal group, a control group and an AD group. AD was established by injecting \u03b2-amyloid",
        "keywords": [
            "\u03b2-Amyloid",
            "Alzheimer's disease",
            "Apoptosis",
            "Mitochondrial pathway"
        ],
        "venue": "Neuroembryology and Aging",
        "year": 2008,
        "id": "bwisKzaf"
    },
    "kysuLhFZ": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Department of Laboratory Medicine"
            },
            {
                "name": "Wan-Ying Hao",
                "org": "Department of Laboratory Medicine"
            },
            {
                "name": "Xiao-Xia Fan",
                "org": "Department of Laboratory Medicine"
            },
            {
                "name": "Hao Wang",
                "org": "Department of Laboratory Medicine"
            },
            {
                "name": "Ling-Zhen Zhang",
                "org": "Department of Laboratory Medicine"
            },
            {
                "name": "Qing-Mei Mi",
                "org": "Department of Laboratory Medicine"
            },
            {
                "name": "Ren-Qian Zhong",
                "org": "Department of Laboratory Medicine"
            }
        ],
        "title": "Effect of HL-60 cells stimulated by IFN-\u03b3 and IL-10 to express B cell activating factor via transcriptional pathway",
        "abstract": "Objective: To explore the effect of IFN-\u03b3, IL-10 and IL-4 on B cell activating factor (BAFF) expression in human HL-60 cells, a kind of myeloid tumor cell lines, and its possible regulation mechanism. Methods: Cultured human HL-60 cells were treated with IFN-\u03b3, IL-10 and IL-4 for 1-3 days. The expression of membrane-bound BAFF on HL-60 cells was examined by flow cytometry, the amount of soluble BAFF was detected by ELISA assay, and the level of BAFF mRNA was tested by real-time PCR method. A functional 1021 bp fragment of the 5'-flanking region of the human BAFF gene (-1349 to -329 bp) was cloned and investigated with serial 5'-deletion. The 5'-deleted promoters were recombinated with chloramphenicol acetyltransferase (CAT) as reporter gene. These five recombinant plasmids were transiently transfected to HL-60 cells with liposomal transfection method. Promoters activities were determined by CAT reporter gene assay (CAT-ELISA) in those transfected cells treated with different cytokines. Results: The results showed that the expression of membrane-bound BAFF, soluble BAFF and BAFF mRNA in human HL-60 cells were significantly elevated (P < 0.05) after incubated with IFN-\u03b3 and IL-10. In addition, IFN-\u03b3 and IL-10 showed significantly (P < 0.05) increased effects on promoter activity in human BAFF gene. And the cytokines-responsive sequences were located between -929 and -719 bp of the BAFF promoter region. Conclusion: The enhancement of IFN-\u03b3 and IL-10 on BAFF expression and synthesis were regulated by promoter activation. Our in vitro studies also raise the possibility to investigate the mechanisms regulating BAFF expression in other tumor cells of myeloid origin under pathological circumstances.",
        "keywords": [
            "B cell activating factor",
            "Cytokines",
            "HL-60 cells",
            "Promoter"
        ],
        "venue": "Chinese Journal of Microbiology and Immunology",
        "year": 2008,
        "id": "kysuLhFZ"
    },
    "CBCjlhMA": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "College of Plant Protection"
            },
            {
                "name": "Juntao Feng",
                "org": "Technology and Engineering Center of Biopesticide"
            },
            {
                "name": "Zhiqing Ma",
                "org": "Technology and Engineering Center of Biopesticide"
            },
            {
                "name": "Xing Zhang",
                "org": "Technology and Engineering Center of Biopesticide"
            }
        ],
        "title": "Optimum technology for extracting total alkaloid from an insecticidal plant Tripterygium wilfordii Hook with ethanol",
        "abstract": "To make the best of the alkaloids, the main insecticidal components in Tripterygium wilfordii Hook. The extraction technology of the total alkaloid from root bark of T wilfordii with acid ethanol was studied by method of orthogonal design. Combination artificial neural network with traditional orthogonal experiment, a new method for analyzing, processing and optimizing the test data was applied. By using this new method, the optimum extraction condition was obtained as follows: Root bark powder 30 mesh, pH value 2.5, ethanol concentration 65%, solid-liquid ratio 1:10, duration of extraction 2h and extracting times 2. Applying this extracting technology, the costs of production was reduced, and the energy consuming was decreased, but the total alkaloid content was increased. The results show that this new method is reasonable and practicable.",
        "keywords": [
            "Artificial neural networks",
            "Botanical insecticides",
            "Extraction technology",
            "Total alkaloid",
            "Tripterygium wilfordii Hook"
        ],
        "venue": "Nongye Gongcheng Xuebao/Transactions of the Chinese Society of Agricultural Engineering",
        "year": 2008,
        "id": "CBCjlhMA"
    },
    "JdXZcoeH": {
        "authors": [
            {
                "name": "Lun Cai",
                "org": "Research Center for Biological Therapy"
            },
            {
                "name": "Zheng Zhang",
                "org": "Research Center for Biological Therapy"
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Haiyan Wang",
                "org": "Department of Infectious Diseases"
            },
            {
                "name": "Junliang Fu",
                "org": "Research Center for Biological Therapy"
            },
            {
                "name": "Shuye Zhang",
                "org": "Research Center for Biological Therapy"
            },
            {
                "name": "Min Shi",
                "org": "Research Center for Biological Therapy"
            },
            {
                "name": "Hui Zhang",
                "org": "Research Center for Biological Therapy"
            },
            {
                "name": "Yongping Yang",
                "org": "The Ninth Department of Clinic"
            },
            {
                "name": "Hao Wu",
                "org": "Department of Infectious Diseases"
            },
            {
                "name": "Po Tien",
                "org": "Institute of Microbiology"
            },
            {
                "name": "Fu-Sheng Wang",
                "org": "Research Center for Biological Therapy"
            }
        ],
        "title": "Functional impairment in circulating and intrahepatic NK cells and relative mechanism in hepatocellular carcinoma patients",
        "abstract": "Functional defects in natural killer (NK) cells have been proposed to be responsible for the failure of anti-tumor immune responses. Whether and how NK cells are impaired in hepatocellular carcinoma (HCC) patients remain unknown. In this study, we found that HCC patients displayed a dramatic reduction in peripheral CD56",
        "keywords": [
            "Hepatocellular carcinoma",
            "Liver",
            "",
            "NK cells",
            "",
            "Regulatory T cells",
            ""
        ],
        "venue": "Clinical Immunology",
        "year": 2008,
        "id": "JdXZcoeH"
    },
    "Es0cFMdt": {
        "authors": [
            {
                "name": "Hao Chen",
                "org": ""
            },
            {
                "name": "Ying Zhang",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Hai-Yang Xie",
                "org": ""
            },
            {
                "name": "Shu-Sen Zheng",
                "org": ""
            }
        ],
        "title": "Role of basic studies in expanding the donor pool for liver transplantation",
        "abstract": "Background: Liver transplantation is an effective treatment for end-stage liver disease, but a huge gap remains between the number of people who need a liver transplant and the number of organs available. In order to maximize donor organ access for adult and pediatric recipients, novel surgical and liver replacement procedures have evolved. Newer surgical techniques include split cadaveric liver transplantation and living donor liver transplantation (LDLT). With marginal and abnormal donor livers, despite tremendous advances in surgical technology, individual surgical procedure can not be completely brought into play unless effective measurements and basal studies are undertaken. Data sources: A literature search of MEDLINE and the Web of Science database using \"liver transplantation\" and \"expanding donor pool\" was conducted and research articles were reviewed. Results: Therapies directed toward scavenging O",
        "keywords": [
            "Expanding donor pool",
            "Liver transplantation",
            "Living donor liver transplantation",
            "Non-heart beating donor",
            "Split liver transplantation"
        ],
        "venue": "Hepatobiliary and Pancreatic Diseases International",
        "year": 2008,
        "id": "Es0cFMdt"
    },
    "QqmYT10W": {
        "authors": [
            {
                "name": "Feng Zhang",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Li-Ming Wu",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Qi-Xing Chen",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Hai-Yang Xie",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Xiao-Wen Feng",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            }
        ],
        "title": "Predictive value of expression and promoter hypermethylation of XAF1 in hepatitis B virus-associated hepatocellular carcinoma treated with transplantation",
        "abstract": "Background: Transcriptional regulation of the putative tumor suppressor gene X-linked inhibitor of apoptosis protein-associated factor 1 (XAF1) by promoter methylation has been related to tumor progression in gastric and bladder cancer. The aim of this study was to investigate the methylation status and expression level of XAF1 in human hepatitis B virus (HBV)-associated hepatocellular carcinoma (HCC) treated with liver transplantation (LT), and to evaluate potential predictive value for tumor recurrence. Methods: The expression level and methylation status of XAF1 in three liver cancer cell lines (SMMC-7721, HepG2, and Hep3B) and 65 cases of HBV-associated HCC following LT were analyzed by RT-PCR (RT, reverse-transcriptase), immunohistochemistry, and methylation-specific polymerase chain reaction (PCR). Results: XAF1 transcripts were not observed or present at low levels in liver cancer cell lines and were restored by treatment with demethylating agent 5-aza-2\u2032-deoxycytidine (5-Aza-dC). In vivo, methylation status was associated with protein level of XAF1 (P < 0.001) and serum level of alpha-fetoprotein (AFP) (P = 0.009). The expression pattern of XAF1 was associated with portal vein tumor thrombi (PVTT), preoperative AFP level, tumor size, and recurrence. Multivariate analysis revealed that expression level of XAF1 was an independent factor for predicting recurrence-free survival [hazard ratio 0.237, 95% confidence interval (CI) 0.095-0.592, P = 0.002]. However, no significant association was found between methylation status and the risk of tumor recurrence. Conclusion: Promoter hypermethylation is a critical, but not the sole, mechanism for gene silencing of XAF1 in HCC. Protein level of XAF1 may serve as a potential biomarker for tumor recurrence after LT. \u00a9 2008 Society of Surgical Oncology.",
        "keywords": [
            ""
        ],
        "venue": "Annals of Surgical Oncology",
        "year": 2008,
        "id": "QqmYT10W"
    },
    "GYP7txoW": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "College of Plant Protection"
            },
            {
                "name": "Haizhen Mo",
                "org": "Department of Food Science"
            },
            {
                "name": "Hao Zhang",
                "org": "Department of Food Science"
            }
        ],
        "title": "Comparison of methods for selenium extraction from selenium enriched vegetables",
        "abstract": "As selenium compound is sensitive to heat and oxygen, sample pre-treatment is necessary to ensure the accurate analysis of selenium content and speciation. The influence of temperatures, enzyme and ultrasonic treatment on the selenium extraction rate was studied and the selenium extraction process for selenium enriched cabbage was optimized. Selenium in the cabbage was mainly in non-protein combined form, in the alkali solution the selenium extraction rate was low, whereas soaked in acidic solution for 4 h, the majority water-soluble selenium compounds were extracted. Ultrasonic treatments for 120 s in an acidic solution at pH 2.0, the major part of selenium component In se-enrlched cabbage were extracted.",
        "keywords": [
            ""
        ],
        "venue": "Agro Food Industry Hi-Tech",
        "year": 2009,
        "id": "GYP7txoW"
    },
    "DfOaLwqY": {
        "authors": [
            {
                "name": "Feng Gao",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Xiao Xu",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Qi Ling",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Jian Wu",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Hai-Yang Xie",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Hui-Ping Wang",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            }
        ],
        "title": "Efficacy and safety of moderately steatotic donor liver in transplantation",
        "keywords": [
            "Liver function",
            "Liver steatosis",
            "Liver transplantation",
            "Survival"
        ],
        "venue": "Hepatobiliary and Pancreatic Diseases International",
        "year": 2009,
        "id": "DfOaLwqY"
    },
    "yBTRDX5n": {
        "authors": [
            {
                "name": "Xiao Xu",
                "org": ""
            },
            {
                "name": "Qing-Hong Ke",
                "org": ""
            },
            {
                "name": "Zhe-Xin Shao",
                "org": ""
            },
            {
                "name": "Jian Wu",
                "org": ""
            },
            {
                "name": "Jun Chen",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Shu-Sen Zheng",
                "org": ""
            }
        ],
        "title": "The value of serum \u03b1-fetoprotein in predicting tumor recurrence after liver transplantation for hepatocellular carcinoma",
        "keywords": [
            "\u03b1-Fetoprotein",
            "Hepatocellular carcinoma",
            "Liver transplantation",
            "Recurrence"
        ],
        "venue": "Digestive Diseases and Sciences",
        "year": 2009,
        "id": "yBTRDX5n"
    },
    "NQQgKGuf": {
        "authors": [
            {
                "name": "Yigang Qian",
                "org": "Department of Hepatobiliary Pancreatic Surgery"
            },
            {
                "name": "Junfang Deng",
                "org": "Department of Hepatobiliary Pancreatic Surgery"
            },
            {
                "name": "Haiyang Xie",
                "org": "Department of Hepatobiliary Pancreatic Surgery"
            },
            {
                "name": "Lei Geng",
                "org": "Department of Hepatobiliary Pancreatic Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Hepatobiliary Pancreatic Surgery"
            },
            {
                "name": "Yan Wang",
                "org": "Department of Hepatobiliary Pancreatic Surgery"
            },
            {
                "name": "Shenyong Yin",
                "org": "Department of Hepatobiliary Pancreatic Surgery"
            },
            {
                "name": "Xiaowen Feng",
                "org": "Department of Hepatobiliary Pancreatic Surgery"
            },
            {
                "name": "Shusen Zheng",
                "org": "Department of Hepatobiliary Pancreatic Surgery"
            }
        ],
        "title": "Regulation of TLR4-induced IL-6 response in bladder cancer cells by opposing actions of MAPK and PI3K signaling",
        "abstract": "Purpose: Toll-like receptor 4 (TLR4) was found to be aberrantly expressed in bladder cancer, inducing some genes expression and facilitating tumor progression. Recent data suggest that tumor associated Interleukin-6 (IL-6) correlates with tumor size and grade in bladder cancer. However, the molecule mechanisms of the induction of IL-6 response in bladder cancer cells are not well elucidated. In this study, we manage to find out whether TLR4 signaling is involved in the production of IL-6 by human bladder cancer cells, and the detailed molecule mechanisms by which IL-6 is up-regulated. Methods: We selected human bladder cancer T24 cell line in the present study, and examined its expression of TLR4 and CD14 by using flow cytometry. TLR4 signaling was activated by lipopolysaccharide (LPS) and IL-6 secretion in culture supernatants was tested by using ELISA kit. The expression of p38, ERK, JNK and Akt were determined by western-blot analysis using specific antibodies. Results: Our study demonstrated that CD14 and TLR4 were constitutively expressed in T24 cells and activation of TLR4 signaling by LPS resulted in phosphorylation of MAPK and PI3K pathways and up-regulation of IL-6 in dose- and time-dependent manner. Pretreatment of cells with SB203580 (inhibitor of p38) and PD98059 (inhibitor of ERK) attenuated LPS-induced IL-6 expression, whereas LY294002 (inhibitor of PI3K) markedly amplified the LPS-stimulated synthesis of IL-6. Conclusions: Our results demonstrate that activation of TLR4 signaling in bladder cancer cells induces tumor-associated IL-6 expression via activation of p38 and ERK, whereas activation of PI3K/Akt exerts an opposing action. \u00a9 2008 Springer-Verlag.",
        "keywords": [
            "Bladder cancer",
            "IL-6",
            "MAPK",
            "PI3K",
            "TLR4"
        ],
        "venue": "Journal of Cancer Research and Clinical Oncology",
        "year": 2009,
        "id": "NQQgKGuf"
    },
    "TtE5Kosm": {
        "authors": [
            {
                "name": "Xue-Qin Meng",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Xuan Zhang",
                "org": "State Key Laboratory for Diagnosis and Treatment of Infectious Diseases"
            },
            {
                "name": "Jun Fan",
                "org": "State Key Laboratory for Diagnosis and Treatment of Infectious Diseases"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Bing Hao",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Xiao-Ming Chen",
                "org": "State Key Laboratory for Diagnosis and Treatment of Infectious Diseases"
            },
            {
                "name": "Wei-Hang Ma",
                "org": "State Key Laboratory for Diagnosis and Treatment of Infectious Diseases"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            }
        ],
        "title": "Detection of human leukocyte antigen compatibility and antibodies in liver transplantation in China",
        "abstract": "Background: The exact roles of human leukocyte antigen (HLA) compatibility, HLA antibodies and underlying diseases in acute rejection of liver transplants are not clear. Moreover, cytomegalovirus (CMV) infection, one of the most common infections after transplantation, is related to HLA genotype and the incidence of acute rejection. Methods: Since there are controversial reports, we analyzed the impact of HLA matching, HLA antibodies and underlying diseases in 38 liver transplant recipients in China, and assessed the association of CMV infection and HLA compatibility. Results: The frequency of no HLA compatibility was high in patients without antigenemia (P=0.019). All 17 patients with HLA-A matching developed antigenemia (P<0.05). Patients with three HLA locus matches were not found in patients with acute rejection (P<0.05), and no relationship between HLA antibodies and acute rejection was found (P>0.05). In patients with acute rejection, no differences were found in the incidence of acute rejection in transplants for hepatitis B, tumors, or combined hepatitis B and tumors (P>0.05). Conclusions: There are fewer acute rejections in transplants with more HLA compatibilities. Specific investigations of underlying diseases and HLA typing may be necessary in liver transplantation. The mechanisms of CMV infection and HLA matching should be further studied. HLA before transplantation should be examined for the prevention of acute rejection and CMV infection. \u00a9 2009, Hepatobiliary Pancreat Dis Int. All rights reserved.",
        "keywords": [
            "Cytomegalovirus",
            "HLA antibodies",
            "HLA matching",
            "Liver transplantation"
        ],
        "venue": "Hepatobiliary and Pancreatic Diseases International",
        "year": 2009,
        "id": "TtE5Kosm"
    },
    "mP00HCVP": {
        "authors": [
            {
                "name": "Wei Hou",
                "org": "Institute of Medical Virology"
            },
            {
                "name": "Xu Wang",
                "org": "Children's Hospital of Philadelphia"
            },
            {
                "name": "Li Ye",
                "org": "Children's Hospital of Philadelphia"
            },
            {
                "name": "Lin Zhou",
                "org": "Children's Hospital of Philadelphia"
            },
            {
                "name": "Zhan-Qiu Yang",
                "org": "Institute of Medical Virology"
            },
            {
                "name": "Eric Riedel",
                "org": "Children's Hospital of Philadelphia"
            },
            {
                "name": "Wen-Zhe Ho",
                "org": "Children's Hospital of Philadelphia"
            }
        ],
        "title": "Lambda interferon inhibits human immunodeficiency virus type 1 infection of macrophages",
        "abstract": "The newly identified type III interferon (IFN-\u03bb) has antiviral activity against a broad spectrum of viruses. We thus examined whether IFN-\u03bb has the ability to inhibit human immunodeficiency virus type 1 (HIV-1) infection of blood monocyte-derived macrophages that expressed IFN-\u03bb receptors. Both IFN-\u03bb1 and IFN-\u03bb2, when added to macrophage cultures, inhibited HIV-1 infection and replication. This IFN-\u03bb-mediated anti-HIV-1 activity is broad, as IFN-\u03bb could inhibit infection by both laboratory-adapted and clinical strains of HIV-1. Investigations of the mechanism(s) responsible for the IFN-\u03bb action showed that although IFN-\u03bb had little effect on HIV-1 entry coreceptor CCR5 expression, IFN-\u03bb induced the expression of CC chemokines, the ligands for CCR5. In addition, IFN-\u03bb upregulated intracellular expression of type I IFNs and APOBEC3G/3F, the newly identified anti-HIV-1 cellular factors. These data provide direct and compelling evidence that IFN-\u03bb, through both extracellular and intracellular antiviral mechanisms, inhibits HIV-1 replication in macrophages. These findings indicate that IFN-\u03bb may have therapeutic value in the treatment of HIV-1 infection. Copyright \u00a9 2009, American Society for Microbiology. All Rights Reserved.",
        "keywords": [
            ""
        ],
        "venue": "Journal of Virology",
        "year": 2009,
        "id": "mP00HCVP"
    },
    "Fd2BkgY0": {
        "authors": [
            {
                "name": "Chunyu Zeng",
                "org": "Department of Cardiology"
            },
            {
                "name": "Van Anthony M. Villar",
                "org": "Department of Pediatrics"
            },
            {
                "name": "Peiying Yu",
                "org": "Department of Pediatrics"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Cardiology"
            },
            {
                "name": "Pedro A. Jose",
                "org": "Department of Physiology and Biophysics"
            }
        ],
        "title": "Reactive oxygen species and dopamine receptor function in essential hypertension",
        "abstract": "Essential hypertension is a major risk factor for stroke, myocardial infarction, and heart and kidney failure. Dopamine plays an important role in the pathogenesis of hypertension by regulating epithelial sodium transport and by interacting with vasoactive hormones and humoral factors. However, the mechanisms leading to impaired dopamine receptor function in hypertension states are not clear. Compelling experimental evidence indicates a role of reactive oxygen species (ROS) in hypertension, and there are increasing pieces of evidence showing that in conditions associated with oxidative stress, which is present in hypertensive states, dopamine receptor effects, such as natriuresis, diuresis, and vasodilation, are impaired. The goal of this review is to present experimental evidence that has led to the conclusion that decreased dopamine receptor function increases ROS activity and vice versa. Decreased dopamine receptor function and increased ROS production, working in concert or independent of each other, contribute to the pathogenesis of essential hypertension.",
        "keywords": [
            "Dopamine receptor",
            "Essential hypertension",
            "Reactive oxygen species"
        ],
        "venue": "Clinical and Experimental Hypertension",
        "year": 2009,
        "id": "Fd2BkgY0"
    },
    "hs3UcDvM": {
        "authors": [
            {
                "name": "Chunyu Zeng",
                "org": "Department of Cardiology"
            },
            {
                "name": "Yu Han",
                "org": "Department of Cardiology"
            },
            {
                "name": "Hefei Huang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Changqing Yu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Hongmei Ren",
                "org": "Department of Cardiology"
            },
            {
                "name": "Weibin Shi",
                "org": "Department of Cardiology"
            },
            {
                "name": "Duofen He",
                "org": "Department of Cardiology"
            },
            {
                "name": "Lan Huang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Chengming Yang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xukai Wang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Cardiology"
            },
            {
                "name": "Pedro A. Jose",
                "org": "Departments of Physiology and Biophysics"
            }
        ],
        "title": "D1-like receptors inhibit insulin-induced vascular smooth muscle cell proliferation via down-regulation of insulin receptor expression",
        "abstract": "Objective Vascular smooth muscle cell (VSMC) proliferation is central to the development of vascular diseases, including hypertension, which is regulated by numerous hormones and humoral factors. Our previous study showed that the stimulatory effect of norepinephrine on VSMC proliferation is inhibited by D1-like receptors and the D",
        "keywords": [
            "Dopamine receptor",
            "Insulin",
            "Proliferation",
            "Vascular smooth muscle cells"
        ],
        "venue": "Journal of Hypertension",
        "year": 2009,
        "id": "hs3UcDvM"
    },
    "rymohvrl": {
        "authors": [
            {
                "name": "Li Ye",
                "org": ""
            },
            {
                "name": "Xu Wang",
                "org": ""
            },
            {
                "name": "Shihong Wang",
                "org": ""
            },
            {
                "name": "Yanjian Wang",
                "org": ""
            },
            {
                "name": "Li Song",
                "org": ""
            },
            {
                "name": "Wei Hou",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "He Li",
                "org": ""
            },
            {
                "name": "Wenzhe Ho",
                "org": ""
            }
        ],
        "title": "CD56+ T cells inhibit hepatitis C virus replication in human hepatocytes",
        "abstract": "CD56",
        "keywords": [
            ""
        ],
        "venue": "Hepatology",
        "year": 2009,
        "id": "rymohvrl"
    },
    "0DBifa0M": {
        "authors": [
            {
                "name": "Zhipeng Yu",
                "org": "Key Laboratory of Creen Chemistry and Technology"
            },
            {
                "name": "Xiaohua Liu",
                "org": "Key Laboratory of Creen Chemistry and Technology"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Creen Chemistry and Technology"
            },
            {
                "name": "Lili Lin",
                "org": "Key Laboratory of Creen Chemistry and Technology"
            },
            {
                "name": "Xiaoming Feng",
                "org": "Key Laboratory of Creen Chemistry and Technology"
            }
        ],
        "title": "Bifunctional guanidine via an amino amide skeleton for asymmetric michael reactions of \u00df-ketoesters with nitroolefins: A concise synthesis of bicyclic \u03b2- Amino acids",
        "abstract": "Two activations are better than one: The chiral bifunctional guanidine 1, which features an amino amide backbone, catalyzes the asymmetric Michael addition of a range of substrates and gives products with excellent stereoselectivities. The method also allows the efficient synthesis of optically pure \u03b2-amino acid esters. Both the guanidine group and the NH proton of the amide were important for the dual activation. \u00a9 2009 Wiley-VCH Verlag GmbH & Co. KGaA.",
        "keywords": [
            "Amino acids",
            "Asymmetric synthesis",
            "Guanidines",
            "Michael addition",
            "Organocatalysis"
        ],
        "venue": "Angewandte Chemie - International Edition",
        "year": 2009,
        "id": "0DBifa0M"
    },
    "IINd1HLP": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Ruifeng Zhang",
                "org": ""
            },
            {
                "name": "Weiyan Yao",
                "org": ""
            },
            {
                "name": "Jiancheng Wang",
                "org": ""
            },
            {
                "name": "Aihua Qian",
                "org": ""
            },
            {
                "name": "Minmin Qiao",
                "org": ""
            },
            {
                "name": "Yongping Zhang",
                "org": ""
            },
            {
                "name": "Yaozong Yuan",
                "org": ""
            }
        ],
        "title": "Decreased expression of angiotensin-converting enzyme 2 in pancreatic ductal adenocarcinoma is associated with tumor progression",
        "abstract": "Angiotensin II (ANG II), the biologically active peptide of the renin-angiotensin system (RAS), is generated by angiotensin-converting enzyme (ACE) and is a regulator of cardiovascular homeostasis. Recently, there has been increasing evidence that ANG II is involved in the regulation of cell proliferation and migration, as well as angiogenesis via the ANG II-type 1 receptor (AT1R). These findings suggest that the ACE-ANG II-AT1R pathway is related to cancer biology. Previous reports have shown that ACE is preferentially expressed in pancreatic ductal adenocarcinoma (PDAC) tissues. Recently a homologue of ACE, angiotensin-converting enzyme 2 (ACE2), was reported to counterbalance the function of ACE, but the expression and role of ACE2 in PDAC are still unclear. In the present study, we analyzed the expression of ACE2 in invasive human PDAC and surrounding non-malignant tissues by Western blot analysis and immunohistochemistry. The ANG II concentration in homogenates of pancreatic tissues was measured with ELISA, and ACE2 protein was detected by Western blot analysis in BxPC3 and SW1990 human pancreatic ductal cancer cells. We have shown for the first time that the expression of ACE2 is decreased in PDAC tissues, in which ANG II was accumulated. Treatment of BxPC3 and SW1990 cells with ANG II decreased the expression of ACE2. Therefore, ANG II may contribute to the down-regulation of ACE2. Moreover, reduction of ACE2 expression by RNA interference promoted the proliferation of cultured pancreatic cancer cells. These findings suggest that ACE2 may have clinical potential as a novel molecular target for the treatment of PDAC. \u00a9 2009 Tohoku University Medical Press.",
        "keywords": [
            "Angiotensin II",
            "Angiotensin-converting enzyme 2",
            "Angiotension converting enzyme",
            "Pancreatic ductal adenocarcinoma",
            "Proliferation"
        ],
        "venue": "Tohoku Journal of Experimental Medicine",
        "year": 2009,
        "id": "IINd1HLP"
    },
    "OO5WNs12": {
        "authors": [
            {
                "name": "Xin-xing Zhang",
                "org": "Third Department of Oncology"
            },
            {
                "name": "Cong-hua Xie",
                "org": "Department of Radiochemotherapy"
            },
            {
                "name": "Yong Xu",
                "org": "Third Department of Oncology"
            },
            {
                "name": "Di Deng",
                "org": "Department of Radiochemotherapy"
            },
            {
                "name": "Yan-hai Zhao",
                "org": "Department of Radiotherapy"
            },
            {
                "name": "Bing-wen Zou",
                "org": "Third Department of Oncology"
            },
            {
                "name": "Lin Zhou",
                "org": "Third Department of Oncology"
            },
            {
                "name": "Mei Li",
                "org": "First Department of Oncology"
            },
            {
                "name": "Jin Wang",
                "org": "Third Department of Oncology"
            },
            {
                "name": "Wei-ping Liu",
                "org": "Department of Pathology"
            },
            {
                "name": "Mei-juan Huang",
                "org": "State Key Laboratory of Biotherapy"
            }
        ],
        "title": "Salvage Treatment Improved Survival of Patients With Relapsed Extranodal Natural Killer/T-Cell Lymphoma, Nasal Type",
        "abstract": "Purpose: To evaluate the clinical outcome of salvage treatment for patients with relapsed natural killer (NK)/T-cell lymphoma, nasal type. Methods and Materials: Forty-four patients who had achieved complete response during initial treatment and experienced histologically proven relapse were reviewed. Twenty-nine of them received salvage treatment with radiotherapy (RT) alone (n = 7), chemotherapy (CT) alone (n = 10), or both RT and CT (n = 12); the other 15 patients received best supportive care alone. Results: The estimated 5-year overall survival (OS) rate for patients with or without salvage treatment was 37.8% vs. 0 (p < 0.0001), respectively. Salvage CT did not improve survival of relapsed Stage IE and IIE patients. Among relapsed Stage IIIE and IVE patients who received salvage treatment, RT developed significantly better survival when compared with that of non-RT (1-year OS, 62.5% vs. 0, p = 0.006). Relapsed Ann Arbor stage and receiving salvage treatment were found to be significant factors influencing OS at both univariate and multivariate levels. Conclusions: Salvage treatment improved survival in patients with relapsed NK/T-cell lymphoma, nasal type. Salvage RT may play an important role in salvage treatment of relapsed extranodal NK/T-cell lymphoma. \u00a9 2009 Elsevier Inc. All rights reserved.",
        "keywords": [
            "Extranodal NK/T-cell lymphoma",
            "Retrospective analysis",
            "Salvage treatment"
        ],
        "venue": "International Journal of Radiation Oncology Biology Physics",
        "year": 2009,
        "id": "OO5WNs12"
    },
    "tRKITXz0": {
        "authors": [
            {
                "name": "Yuan-Xing Liu",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Li-Ming Jin",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Hai-Yang Xie",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Guo-Ping Jiang",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Yan Wang",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Xiao-Wen Feng",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Hui Chen",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Sheng Yan",
                "org": "Department of Surgery"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Department of Hepatobiliary Pancreatic Surgery"
            }
        ],
        "title": "Mycophenolate mofetil attenuates liver ischemia/reperfusion injury in rats",
        "abstract": "Mycophenolate mofetil (MMF) has been gradually introduced into clinical liver transplantation in recent years. However, the effects of MMF on hepatic ischemia/reperfusion (I/R) injury and the potential mechanisms involved are not totally understood. We aimed to evaluate whether MMF could attenuate hepatic I/R injury. MMF (20 mg/kg) or vehicle was administered to Wistar rats by gavage. The rats were then subjected to hepatic ischemia. Liver cell apoptosis and the levels of aspartate aminotransferase, myeloperoxidase (MPO), xanthine oxidase (XOD) and malondialdehyde (MDA) were determined. Expression of vascular cell adhesion molecule-1 (VCAM-1) and activation of mitogen-activated protein kinases (MAPKs) were also investigated. Furthermore, the hepatic microcirculation was observed by intravital fluorescence microscopy. Rats pretreated with MMF exhibited significant alleviation of their postischemic liver function. Liver cell apoptosis and the tissue MPO, XOD and MDA levels were decreased by MMF pretreatment. MMF also improved I/R-induced hemodynamic turbulence, as evidenced by reduced hepatic perfusion failure and decreased numbers of rolling and adherent leukocytes. I/R injury induced activation of the MAPKs pathway while expression of VCAM-1 was downregulated by MMF pretreatment. In summary, MMF attenuates hepatic I/R injury through suppression of the production of reactive oxygen species and amelioration of postischemic microcirculatory disturbances. \u00a9 2009 European Society for Organ Transplantation.",
        "keywords": [
            "Ischemia/reperfusion injury",
            "Microcirculation",
            "Mitogen-activated protein kinases",
            "Mycophenolate mofetil",
            "Reactive oxygen species"
        ],
        "venue": "Transplant International",
        "year": 2009,
        "id": "tRKITXz0"
    },
    "hhx3EH2b": {
        "authors": [
            {
                "name": "Qing-Lian Wen",
                "org": "Department of Oncology"
            },
            {
                "name": "Mao-Bin Meng",
                "org": "Division of Thoracic Oncology"
            },
            {
                "name": "Bo Yang",
                "org": "Department of Oncology"
            },
            {
                "name": "Ling-Li Tu",
                "org": "Division of Thoracic Oncology"
            },
            {
                "name": "Li Jia",
                "org": "Division of Thoracic Oncology"
            },
            {
                "name": "Lin Zhou",
                "org": "Division of Thoracic Oncology"
            },
            {
                "name": "Yong Xu",
                "org": "Division of Thoracic Oncology"
            },
            {
                "name": "You Lu",
                "org": "Division of Thoracic Oncology"
            }
        ],
        "title": "Endostar, a recombined humanized endostatin, enhances the radioresponse for human nasopharyngeal carcinoma and human lung adenocarcinoma xenografts in mice",
        "abstract": "The purpose of this paper is to determine the efficacy of combining radiation therapy with endostar, a recombined humanized endostatin, in human nasopharyngeal carcinoma and human lung adenocarcinoma xenografts. Tumor xenografts were established in the hind limb of male athymic nude mice (BALB/c-nu) by subcutaneous transplantation. The tumor-bearing mice were assigned into four treatment groups: sham therapy (control), endostar (20 mg/kg, once daily for 10 days), radiation therapy (6 Gray per day to 30 Gray, once a day for 1 week), and endostar plus radiation therapy (combination). The experiment was repeated and mice were killed at days 3, 6, and 10 after initiation therapy, and the tumor tissues and blood samples were collected to analyze the kinetics of antitumor, antiangiogenesis, and antivascularization responses of different therapies. In human nasopharyngeal carcinoma and human lung adenocarcinoma xenografts, endostar significantly enhanced the effects of tumor growth inhibition, endothelial cell and tumor cell apoptosis induction, and improved tumor cell hypoxia of radiation therapy. Histological analyses demonstrated that endostar plus radiation also induced a significant reduction in microvascular density, microvascular area, and vascular endothelial growth factor and matrix metalloproteinase-2 expression compared with radiation and endostar alone respectively. We concluded that endostar significantly sensitized the function of radiation in antitumor and antiangiogenesis in human nasopharyngeal carcinoma and human lung adenocarcinoma xenografts by increasing the apoptosis of the endothelial cell and tumor cell, improving the hypoxia of the tumor cell, and changing the proangiogenic factors. These data provided a rational basis for clinical practice of this multimodality therapy. \u00a9 2009 Japanese Cancer Association.",
        "keywords": [
            ""
        ],
        "venue": "Cancer Science",
        "year": 2009,
        "id": "hhx3EH2b"
    },
    "37bPkZAK": {
        "authors": [
            {
                "name": "Youling Gong",
                "org": "State Key Laboratory of Biotherapy"
            },
            {
                "name": "Li Ren",
                "org": "Department of Thoracic Oncology"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Thoracic Oncology"
            },
            {
                "name": "Jiang Zhu",
                "org": "Department of Thoracic Oncology"
            },
            {
                "name": "Meijuan Huang",
                "org": "Department of Thoracic Oncology"
            },
            {
                "name": "Xiaojuan Zhou",
                "org": "Department of Thoracic Oncology"
            },
            {
                "name": "Jin Wang",
                "org": "Department of Thoracic Oncology"
            },
            {
                "name": "You Lu",
                "org": "State Key Laboratory of Biotherapy"
            },
            {
                "name": "Mei Hou",
                "org": "Department of Thoracic Oncology"
            },
            {
                "name": "Yuquan Wei",
                "org": "State Key Laboratory of Biotherapy"
            }
        ],
        "title": "Phase II evaluation of nedaplatin and paclitaxel in patients with metastatic esophageal carcinoma",
        "abstract": "Purpose: To evaluate the efficiency and toxicities of nedaplatin and paclitaxel in patients with metastatic carcinoma of the esophagus. Methods: Thirty-nine untreated patients with confirmed metastatic tumors were enrolled. Patients were treated with nedaplatin 80 mg/m",
        "keywords": [
            "Esophageal carcinoma",
            "Metastasis",
            "Nedaplatin",
            "Paclitaxel"
        ],
        "venue": "Cancer Chemotherapy and Pharmacology",
        "year": 2009,
        "id": "37bPkZAK"
    },
    "tSr1OGRW": {
        "authors": [
            {
                "name": "Haiyong Chen",
                "org": "Key Lab of Combined Multi-organ Transplantation"
            },
            {
                "name": "Weilin Wang",
                "org": "Key Lab of Combined Multi-organ Transplantation"
            },
            {
                "name": "Haiyang Xie",
                "org": "Key Lab of Combined Multi-organ Transplantation"
            },
            {
                "name": "Xiao Xu",
                "org": "Key Lab of Combined Multi-organ Transplantation"
            },
            {
                "name": "Jian Wu",
                "org": "Key Lab of Combined Multi-organ Transplantation"
            },
            {
                "name": "Zhijun Jiang",
                "org": "Key Lab of Combined Multi-organ Transplantation"
            },
            {
                "name": "Mangli Zhang",
                "org": "Key Lab of Combined Multi-organ Transplantation"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Lab of Combined Multi-organ Transplantation"
            },
            {
                "name": "Shusen Zheng",
                "org": "Key Lab of Combined Multi-organ Transplantation"
            }
        ],
        "title": "A pathogenic role of IL- 17 at the early stage of corneal allograft rejection",
        "keywords": [
            "Allograft rejection",
            "Cornea transplantation",
            "Th1 cell",
            "Th17 cell"
        ],
        "venue": "Transplant Immunology",
        "year": 2009,
        "id": "tSr1OGRW"
    },
    "twIMmWpB": {
        "authors": [
            {
                "name": "Jian Yang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Zhigang Cui",
                "org": "Department of Cardiology"
            },
            {
                "name": "Duofen He",
                "org": "Department of Cardiology"
            },
            {
                "name": "Hongmei Ren",
                "org": "Department of Cardiology"
            },
            {
                "name": "Yu Han",
                "org": "Department of Cardiology"
            },
            {
                "name": "Changqing Yu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Chunjiang Fu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Zheng Wang",
                "org": "Department of Pediatrics"
            },
            {
                "name": "Chengming Yang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xukai Wang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Cardiology"
            },
            {
                "name": "Laureano D. Asico",
                "org": "Department of Pediatrics"
            },
            {
                "name": "Van Anthony M. Villar",
                "org": "Department of Pediatrics"
            },
            {
                "name": "Ulrich Hopfer",
                "org": "Department of Pediatrics"
            },
            {
                "name": "Mantian Mi",
                "org": "Department of Nutrition and Food Hygiene"
            },
            {
                "name": "Chunyu Zeng",
                "org": "Department of Cardiology"
            },
            {
                "name": "Pedro A. Jose",
                "org": "Department of Pediatrics"
            }
        ],
        "title": "Insulin increases D",
        "abstract": "BackgroundIon transport in the renal proximal tubule (RPT) is regulated by numerous hormones and humoral factors, including insulin and dopamine. Previous studies show an interaction between insulin and the D\"1 receptor. Because both D",
        "keywords": [
            ""
        ],
        "venue": "American Journal of Hypertension",
        "year": 2009,
        "id": "twIMmWpB"
    },
    "02IvcdSK": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Department of Laboratory Medicine"
            },
            {
                "name": "Renqian Zhong",
                "org": "Department of Laboratory Medicine"
            },
            {
                "name": "Wanying Hao",
                "org": "Department of Laboratory Medicine"
            },
            {
                "name": "Hao Wang",
                "org": "Department of Laboratory Medicine"
            },
            {
                "name": "Xiaoxia Fan",
                "org": "Department of Laboratory Medicine"
            },
            {
                "name": "Lingzhen Zhang",
                "org": "Department of Laboratory Medicine"
            },
            {
                "name": "Qingmei Mi",
                "org": "Department of Laboratory Medicine"
            }
        ],
        "title": "Interleukin-10 and interferon-\u03b3 up-regulate the expression of B-cell activating factor in cultured human promyelocytic leukemia cells",
        "abstract": "B-cell activating factor (BAFF) is a potent cell-survival factor, expressed in many hematopoietic cells, for B-cell maturation and activation. It is involved in pathogenesis of autoimmune disorders and B-cell malignancies. Although BAFF is produced by interferon-\u03b3 (IFN-\u03b3) and interleukin-10 (IL-10) in monocytes, the mechanisms of the modulation of BAFF production and expression under normal and pathologic conditions have not been completely elucidated. In this study, we examined the effects of several inflammatory cytokines on BAFF expression in cultured human promyelocytic leukemia (HL-60) cells both at the transcriptional and posttranscriptional level. Incubation of the cells with IL-10 and IFN-\u03b3 elevated the expression of membrane-bound and soluble forms of BAFF. A similar increase in BAFF-specific mRNA was noted in cultured cells. Unexpectedly, interleukin-4 (IL-4) treatment hardly affected BAFF expression at the mRNA and protein levels. Transcriptional regulation was examined in cultures transfected with a human BAFF promoter/reporter gene (chloramphenicol acetyltransferase) construct. IL-10 and IFN-\u03b3 elicited marked enhancement of the human BAFF promoter activity. Collectively, these results demonstrated that IL-10 and IFN-\u03b3 both regulate BAFF expression and synthesis in human promyelocytic leukemia cell cultures, and the activation occurs at the transcriptional level. Crown Copyright \u00a9 2009.",
        "keywords": [
            "B-cell activating factor",
            "Cytokines",
            "Genes",
            "Human promyelocytic leukemia cells",
            "Promoter"
        ],
        "venue": "Experimental and Molecular Pathology",
        "year": 2009,
        "id": "02IvcdSK"
    },
    "0XV6inay": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Liver Carcinoma Therapy and Research Center"
            },
            {
                "name": "Yong-Ping Yang",
                "org": "Liver Carcinoma Therapy and Research Center"
            },
            {
                "name": "Yong-Yi Feng",
                "org": "Liver Carcinoma Therapy and Research Center"
            },
            {
                "name": "Yin-Ying Lu",
                "org": "Liver Carcinoma Therapy and Research Center"
            },
            {
                "name": "Chun-Ping Wang",
                "org": "Liver Carcinoma Therapy and Research Center"
            },
            {
                "name": "Xin-Zhen Wang",
                "org": "Liver Carcinoma Therapy and Research Center"
            },
            {
                "name": "Lin-Jing An",
                "org": "Liver Carcinoma Therapy and Research Center"
            },
            {
                "name": "Xin Zhang",
                "org": "Liver Carcinoma Therapy and Research Center"
            },
            {
                "name": "Fu-Sheng Wang",
                "org": "Liver Carcinoma Therapy and Research Center"
            }
        ],
        "title": "Efficacy of argon-helium cryosurgical ablation on primary hepatocellular carcinoma: A pilot clinical study",
        "abstract": "Background and Objective: Recent years, great progression has been made in treating primary hepatocellular carcinoma (HCC) with argon-helium cryosurgical ablation. This study was to evaluate its efficacy on unresectable primary HCC. Methods: A total of 124 primary HCC patients were divided into early stage, middle stage and advanced stage groups according to BCLC staging classification. Clinical symptoms, tumor size, serum level of alpha-fetoprotein (AFP), complications, and survival time were analyzed. Results: After cryoablation of the tumors, serum level of AFP was reduced in 76 (82.6%) patients, 205 (92.3%) of the 222 tumor lesions were diminished or unchanged. Untill April 2008, 14 patients survived and 110 died. The median survival time was 31.25 months in early stage group, 17.41 months in middle stage group and 6.82 months in advanced stage group. Conclusion: For the patients with unresectable HCC, argon-helium cryosurgical ablation has the advantages of few complications and certain efficacy. \u00a9 2009 Sun Yat-Sen University Cancer.",
        "keywords": [
            "Complication",
            "Cryosurgery",
            "Efficacy",
            "Liver neoplasm",
            "Survival"
        ],
        "venue": "Chinese Journal of Cancer",
        "year": 2009,
        "id": "0XV6inay"
    },
    "0oq8y1r7": {
        "authors": [
            {
                "name": "Zhen-Yu Tang",
                "org": "Department of Neurology"
            },
            {
                "name": "Qi-Dong Yang",
                "org": "Department of Neurology"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Neurology"
            }
        ],
        "title": "Aassociation between gene polymorphism of interleukin-4 C590T and serum level of interleukin-4 and atherothrombotic cerebral infarction",
        "abstract": "Objective: To explore the association between gene polymorphism of interleukin(IL)-4 C590T and serum level of IL-4 and atherothrombotic cerebral infarction (ATCI). Methods: The gene polymorphisms of IL-4 C590T in 159 patients with ATCI and 151 normal control subjects were carried out by polymerase chain reaction (PCR)-restriction fragment length polymorphism (RFLP). The serum level of IL-4 in normal control group was determined with enzyme linked immunosorbent assay (ELISA) method. Results: In the normal control group, the serum level of IL-4 in TT genotype [(31.85 \u00b1 5.68) pg/ml] was higher significantly than those in TC [(28.67 \u00b1 6.00) pg/ml] and CC genotypes [(20.98 \u00b1 0.99) pg/ml], TC genotype was higher significantly than CC genotype (all P < 0.01). The frequencies of genotypes and allele of IL-4 C590T were found no difference in statistics between ATCI group and normal control group (all P > 0.05). Conclusions: IL-4 590T allele is associated with higher level of serum IL-4. The C590T polymorphism is not associated with the incidence of ATCI.",
        "keywords": [
            "Atherothrombotic cerebral infarction",
            "Gene polymorphism",
            "Interleukin-4"
        ],
        "venue": "Journal of Clinical Neurology",
        "year": 2009,
        "id": "0oq8y1r7"
    },
    "nQP7bb7V": {
        "authors": [
            {
                "name": "Ai-Hua Qian",
                "org": "Department of Gastroenterology"
            },
            {
                "name": "Xin-Qiu Liu",
                "org": "Department of Neurobiology"
            },
            {
                "name": "Wei-Yan Yao",
                "org": "Department of Gastroenterology"
            },
            {
                "name": "Hong-Yu Wang",
                "org": "Department of Gastroenterology"
            },
            {
                "name": "Jing Sun",
                "org": "Department of Gastroenterology"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Gastroenterology"
            },
            {
                "name": "Yao-Zong Yuan",
                "org": "Department of Gastroenterology"
            }
        ],
        "title": "Voltage-gated potassium channels in IB4-positive colonic sensory neurons mediate visceral hypersensitivity in the rat",
        "abstract": "OBJECTIVES: Irritable bowel syndrome (IBS) is associated with a state of chronic visceral hypersensitivity, but the underlying molecular mechanisms of visceral hyperalgesia remain elusive. This study was designed to examine changes in the excitability and alterations of voltage-gated K currents in subpopulations of colonic dorsal root ganglion (DRG) neurons in a rat model of IBS-like visceral hypersensitivity.METHODS:The model of IBS-like visceral hypersensitivity was induced by intracolonic infusion of 0.5% acetic acid (AA) in saline from postnatal days 8-21. Experiments were conducted when rats became adults. DRG neurons innervating the colon were identified by 1,1\u2032-dioleoyl-3,3,3\u2032,3-tetramethylindocarbocyanine methanesulfonate (DiI) fluorescence labeling and were immunostained for isolectin B4 (IB4) binding to classify these colonic neurons. Patch-clamp recordings were made from acutely dissociated DiI-labeled DRG neurons, and the expression of K channel in L6-S2 DRG was examined by reverse transcription-polymerase chain reaction (RT-PCR) and western blot.RESULTS:(1) Neonatal AA treatment induced long-lasting visceral hypersensitivity without significant inflammation but with mast cell hyperplasia. (2) Colonic DRG neurons contained IB4-positive and negative neurons with different electrophysiological properties. IB4-positive colonic neurons have longer action potentials (APs) and larger A-type K currents (I",
        "keywords": [
            ""
        ],
        "venue": "American Journal of Gastroenterology",
        "year": 2009,
        "id": "nQP7bb7V"
    },
    "aEDPAXTU": {
        "authors": [
            {
                "name": "Yan Liu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Jian Yang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Hongmei Ren",
                "org": "Department of Cardiology"
            },
            {
                "name": "Duofen He",
                "org": "Department of Cardiology"
            },
            {
                "name": "Annabelle Pascua",
                "org": "Department of Pediatrics"
            },
            {
                "name": "M. Ines Armando",
                "org": "Department of Pediatrics"
            },
            {
                "name": "Chengming Yang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Cardiology"
            },
            {
                "name": "Robin A. Felder",
                "org": "Department of Pathology"
            },
            {
                "name": "Pedro A. Jose",
                "org": "Department of Pediatrics"
            },
            {
                "name": "Chunyu Zeng",
                "org": "Department of Cardiology"
            }
        ],
        "title": "Inhibitory effect of ETB receptor on Na",
        "abstract": "The kidney is important in the long-term regulation of blood pressure and sodium homeostasis. Stimulation of ETB receptors in the kidney increases sodium excretion, in part, by decreasing sodium transport in the medullary thick ascending limb of Henle and in collecting duct. However, the role of ETB receptor on Na",
        "keywords": [
            ""
        ],
        "venue": "Hypertension Research",
        "year": 2009,
        "id": "aEDPAXTU"
    },
    "2dYyuuWG": {
        "authors": [
            {
                "name": "Yu Zhou",
                "org": "Division of Allergy and Immunology"
            },
            {
                "name": "Li Ye",
                "org": "Division of Allergy and Immunology"
            },
            {
                "name": "Qi Wan",
                "org": "Division of Allergy and Immunology"
            },
            {
                "name": "Lin Zhou",
                "org": "Division of Allergy and Immunology"
            },
            {
                "name": "Xu Wang",
                "org": "Division of Allergy and Immunology"
            },
            {
                "name": "Jieliang Li",
                "org": "Division of Allergy and Immunology"
            },
            {
                "name": "Shuxian Hu",
                "org": "Neuroimmunology Laboratory"
            },
            {
                "name": "Dunjin Zhou",
                "org": "Division of Virology"
            },
            {
                "name": "Wenzhe Ho",
                "org": "Division of Allergy and Immunology"
            }
        ],
        "title": "Activation of toll-like receptors inhibits herpes simplex virus-1 infection of human neuronal cells",
        "abstract": "Toll-like receptors (TLRs) play an essential role in initiating intracellular type I interferon (IFN)-mediated innate immunity against viral infections. We examined whether human neuronal cells (primary human neurons, NT2-N and CHP-212 cells) express TLRs and mount type I IFN-mediated innate immunity against herpes simplex virus-1 (HSV-1) infection. Human neuronal cells expressed TLR family members 1-10 and IFN-\u03b1/\u03b2. The activation of TLR3 or TLR8 by double-stranded RNA (poly-I:C) or single-stranded RNA (ssRNA) induced IFN-\u03b1/\u03b2 expression. In addition, HSV-1 infection of human neuronal cells induced IFN-\u03b1 expression. Investigation of the mechanisms showed that poly-I:C or ssRNA treatment enhanced the expression of several IFN regulatory factors. Importantly, the activation of TLR3 or TLR8 by poly-I:C or ssRNA prior to HSV-1 infection reduced the susceptibility of the neuronal cells to infection. These observations indicate that human neuronal cells possess intracellular TLR-mediated innate immune protection against HSV-1 infection. \u00a9 2009 Wiley-Liss, Inc.",
        "keywords": [
            "Herpes simplex virus-1",
            "Human neuronal cells",
            "Poly-I:C",
            "ssRNA",
            "Toll-like receptor",
            "Type I interferons"
        ],
        "venue": "Journal of Neuroscience Research",
        "year": 2009,
        "id": "2dYyuuWG"
    },
    "gAbhHQkp": {
        "authors": [
            {
                "name": "Chunping Wang",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Yinying Lu",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Yan Chen",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Yongyi Feng",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Linjing An",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Xinzhen Wang",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Shuhui Su",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Wenlin Bai",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Lin Zhou",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Yongping Yang",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Dongping Xu",
                "org": "Infectious Disease Institute of PLA"
            }
        ],
        "title": "Prognostic factors and recurrence of hepatitis B-related hepatocellular carcinoma after argon-helium cryoablation: A prospective study",
        "abstract": "To determine the long-term prognosis of hepatocellular carcinoma (HCC) after argon-helium cryoablation and identify the risk factors that predict metastasis and recurrence. A total of 156 patients with hepatitis B-related HCC less than 5 cm in diameter who underwent curative cryoablation were followed up prospectively for tumor metastasis and recurrence. Immunohistochemistry was used to analyze the expression of vascular endothelial growth factor (VEGF). HBV basal core promoter (BCP) and precore mutations were detected by DNA sequence analysis. Post-treatment prognostic factors influencing survival, tumor metastasis and recurrence were assessed by univariate and multivariate analyses. The variables included the expression of VEGF in HCC tissues, clinical and pathologic characteristics of patients, and HBV features (HBV DNA level, HBV genotype, BCP mutation). The median follow-up period of the 156 patients was 37 months (range 8-48 months). The 1-, 2-, and 3-year overall survival rates were 92, 82 and 64%, respectively. The 1-, 2-, and 3-year recurrence-free survival rates were 72, 56 and 43%, respectively. Eighty-five patients (54.5%) had tumor recurrence or metastasis. The multivariate analysis showed that Child-Pugh class and the expression of VEGF in HCC tissues could be used as independent prognostic factors for overall survival. Meanwhile, the expression of VEGF in HCC tissues and HBV BCP mutations were found to be independent prognostic factors for recurrence-free survival. Strong expression of VEGF in HCC tissues and HBV BCP mutations are important risk predictors for recurrence or metastasis of HCC smaller than 5 cm in diameter. \u00a9 2009 Springer.",
        "keywords": [
            "Cryoablation",
            "HBV basal core promoter",
            "Hepatocellular carcinoma",
            "Prognostic factor",
            "Recurrence",
            "Vascular endothelial growth factor"
        ],
        "venue": "Clinical and Experimental Metastasis",
        "year": 2009,
        "id": "gAbhHQkp"
    },
    "fRsdvkZA": {
        "authors": [
            {
                "name": "Ruifeng Zhang",
                "org": "Department of Respiratory Medicine"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Gastroenterology"
            },
            {
                "name": "Qingyun Li",
                "org": "Department of Respiratory Medicine"
            },
            {
                "name": "Jialin Liu",
                "org": "Department of Respiratory Medicine"
            },
            {
                "name": "Weiyan Yao",
                "org": "Department of Gastroenterology"
            },
            {
                "name": "Huanying Wan",
                "org": "Department of Respiratory Medicine"
            }
        ],
        "title": "Up-regulation of two actin-associated proteins prompts pulmonary artery smooth muscle cell migration under hypoxia",
        "abstract": "Hypoxia stimulates the migration of pulmonary artery smooth muscle cells (PASMCs), which contributes to the pathogenesis of pulmonary vessel structural remodeling in hypoxic pulmonary hypertension (HPH). In the present study, we found, using a proteomics-based method, that gelsolin-like actin-capping protein (CapG) and transgelin were preferentially expressed in human (h)PAMSCs under hypoxia compared with normoxia. These two actin-associated proteins, modulate a variety of physiologic processes, including motility of cells, by interacting differently with the actin cytoskeleton. Our study showed that these two genes were up-regulated at both mRNA and protein levels under hypoxia in hPASMCs. As a key transcriptional regulation factor under hypoxia, hypoxia-inducible factor 1\u03b1 (HIF-1\u03b1) up-regulated CapG protein expression under normoxia, and knockdown of HIF-1\u03b1 expression in hPASMCs also inhibited hypoxia induced CapG up-regulation. However, HIF-1\u03b1 could not regulate transgelin expression. Reduction of CapG or transgelin expression in hPASMCs by RNA interference was accompanied by significantly impaired migration ability in vitro, especially under hypoxia. Our study demonstrates that CapG and transgelin were preferentially expressed in hPAMSCs under hypoxia compared with normoxia. Hypoxia stimulates expression of these two actin-associated proteins via HIF-1\u03b1-dependent and -independent pathways, respectively. The up-regulation of these two proteins may contribute to the increased motility of hPASMCs under hypoxia. These findings may contribute to the understanding of the pathogenesis of HPH.",
        "keywords": [
            "CapG",
            "Hypoxia migration",
            "Hypoxia-inducible factor 1\u03b1",
            "Transgelin"
        ],
        "venue": "American Journal of Respiratory Cell and Molecular Biology",
        "year": 2009,
        "id": "fRsdvkZA"
    },
    "JSqXeuTu": {
        "authors": [
            {
                "name": "Li-Ming Wu",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Hai-Yang Xie",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Zhe Yang",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Feng Zhang",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            }
        ],
        "title": "A Single Nucleotide Polymorphism in the Vascular Endothelial Growth Factor Gene Is Associated with Recurrence of Hepatocellular Carcinoma after Transplantation",
        "abstract": "Background: Vascular endothelial growth factor (VEGF), an important regulator of angiogenesis and vascular permeability, is involved in various steps of many malignancies. Gene polymorphisms within the gene encoding VEGF have been shown to be independently associated with an adverse outcome in various malignancies including hepatocellular carcinoma (HCC) with resection. However, no data are available for HCC treated with liver transplantation (LT). Therefore, we investigated association of VEGF genomic polymorphisms with risk for developing HCC and tumor recurrence after LT. Methods: Seven polymorphisms in the VEGF gene (rs699947, rs1570360, rs2010963, rs3024997, rs3025010, rs3025035, rs3025039) were examined in 93 HCC patients treated with LT and 99 controls using Applied Biosystems SNaP-Shot and TaqMan technology. Cox proportional hazard model was used to estimate the hazard ratios associated with polymorphisms. Results: The association between rs3025035 and recurrence was significant (p = 0.003). However, no other SNP in VEGF was associated with recurrence. Interestingly, we found that patients with rs3025035 CT heterozygous was independently associated with a shortened recurrence-free survival (odds ratio: 3.3; 95% confidence interval: 1.8-6.0; p <0.001). Conclusions: Our data suggest that polymorphism rs3025035 in the VEGF gene may be a potential genetic marker for HCC recurrence in LT patients. \u00a9 2009 IMSS.",
        "keywords": [
            "Hepatocellular carcinoma",
            "Polymorphisms",
            "Recurrence",
            "Vascular endothelial growth factor"
        ],
        "venue": "Archives of Medical Research",
        "year": 2009,
        "id": "JSqXeuTu"
    },
    "5nQP3XCa": {
        "authors": [
            {
                "name": "Ruifeng Zhang",
                "org": ""
            },
            {
                "name": "Yingli Wu",
                "org": ""
            },
            {
                "name": "Meng Zhao",
                "org": ""
            },
            {
                "name": "Chuanxu Liu",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Shaoming Shen",
                "org": ""
            },
            {
                "name": "Shihua Liao",
                "org": ""
            },
            {
                "name": "Kun Yang",
                "org": ""
            },
            {
                "name": "Qingyun Li",
                "org": ""
            },
            {
                "name": "Huanying Wan",
                "org": ""
            }
        ],
        "title": "Role of HIF-1\u03b1 in the regulation ACE and ACE2 expression in hypoxic human pulmonary artery smooth muscle cells",
        "abstract": "Angiotensin-converting enzyme (ACE) enhances the proliferation and migration of pulmonary artery smooth muscle cells (PASMCs), which contribute to the pathogenesis of hypoxic pulmonary hypertension (HPH). Previous reports have demonstrated that hypoxia upregulates ACE expression, but the underlying mechanism is unknown. Here, we found that ACE is persistently upregulated in PASMCs on the transcriptional level during hypoxia. Hypoxia-inducible factor 1\u03b1 (HIF-1\u03b1), a key transcription factor activated during hypoxia, was able to upregulate ACE protein expression under normoxia, whereas knockdown of HIF-1\u03b1 expression in PASMCs inhibited hypoxia-induced ACE upregulation. Furthermore, HIF-1\u03b1 can bind and transactivate the ACE promoter directly. Therefore, we report that ACE is a novel target of HIF-1\u03b1. Recently, a homolog of ACE, ACE2, was reported to counterbalance the function of ACE. In contrast to ACE, we found that ACE2 mRNA and protein levels increased during the early stages of hypoxia and decreased to near-baseline levels at the later stages after HIF-1\u03b1 accumulation. Thus HIF-1\u03b1 inhibited ACE2 expression, and the accumulated ANG II catalyzed by ACE is a key mediator in the downregulation of ACE2 by HIF-1\u03b1. Moreover, a reduction of ACE2 expression in PASMCs by RNA interference was accompanied by significantly enhanced proliferation and migration during hypoxia. We conclude that ACE is directly regulated by HIF-1\u03b1, whereas ACE2 is regulated in a bidirectional way during hypoxia and may play a protective role during the development of HPH. In sum, these findings contribute to the understanding of the pathogenesis of HPH. Copyright \u00a9 2009 the American Physiological Society.",
        "keywords": [
            "Angiotensin II",
            "Angiotensin-converting enzyme 2",
            "Hypoxia",
            "Hypoxia-inducible factor 1\u03b1"
        ],
        "venue": "American Journal of Physiology - Lung Cellular and Molecular Physiology",
        "year": 2009,
        "id": "5nQP3XCa"
    },
    "Npi1t4zL": {
        "authors": [
            {
                "name": "Shuang Zhu",
                "org": "School of Life Science and Biopharmacology"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Life Science and Biopharmacology"
            },
            {
                "name": "Cuiyi Liang",
                "org": "School of Life Science and Biopharmacology"
            },
            {
                "name": "Haihua Wu",
                "org": "School of Life Science and Biopharmacology"
            },
            {
                "name": "Haizhen Wu",
                "org": "School of Biological Science and Engineering"
            },
            {
                "name": "Chaohai Wei",
                "org": "College of Environmental Science and Engineering"
            }
        ],
        "title": "A highly efficient method for extracting total DNA from activated sludge of coking wastewater",
        "abstract": "Development of an efficient method to extract high quality total DNA from activated sludge of coking wastewater is a prerequisite for understanding its molecular microbial ecology. In this study, three methods with different combinations of extraction steps (i.e., Freezing and Thawing-Protease K-SDS, Lysozyme-Freezing and Thawing-SDS, and Lysozyme-Freezing and Thawing-Protease K-SDS) for extracting total DNA from activated sludge were compared. The extraction efficiency of total DNA was evaluated by the yield, purity, size, and integrity of the DNA fragments. The effect of PCR inhibitors on the extraction efficiency of total DNA was also investigated. The results showed that Method III (Lysozyme-Freezing and Thawing-Protease K-SDS) was the most efficient extraction method. The DNA yields ranged from 1.90\u03bcg\u00b7g",
        "keywords": [
            "Activated sludge",
            "Coking wastewater",
            "DNA extraction",
            "PCR amplification"
        ],
        "venue": "Huanjing Kexue Xuebao/Acta Scientiae Circumstantiae",
        "year": 2009,
        "id": "Npi1t4zL"
    },
    "t64AF0tr": {
        "authors": [
            {
                "name": "Qiwen Ben",
                "org": "Department of Gastroenterology"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Gastroenterology"
            },
            {
                "name": "Aihua Qian",
                "org": "Department of Gastroenterology"
            },
            {
                "name": "Yaozong Yuan",
                "org": "Department of Gastroenterology"
            }
        ],
        "title": "Clinical characteristics of solid pseudopapillary neoplasm of the pancreas: A meta-analysis of 293 cases",
        "abstract": "Background: Solid pseudopapillary neoplasm of the pancreas (SPNP) is a tumor of low malignant potential, and has been increasingly reported in recent years. Aims: To summarize the clinicopathologic features of SPNP. Methods: A total of 293 SPNP patients were retrieved from China Hospital Knowledge Database (CHKD) using solid-cystic neoplasm/pancreas or solid-pseudopapillary tumor/pancreas as key words from Oct. 1997 to Aug. 2008, and the clinicopathologic features of these patients were analyzed. Results: The ratio of male to female in SPNP was 1:8.2, the average age was 27.3 years old, and the clinical manifestations were nonspecific. Imaging findings of SPNP showed solid and cystic areas in different proportion, and the diagnosis rate was 41.0% by imaging examination before operation. All masses were solitary lesions, and the largest mean diameter was 7.6 cm. The capsule was complete in 218 patients and incomplete in 75. Of the 196 SPNP patients receiving treatment, the surgical resection rate was 94.9%. Two hundred and twenty patients were followed up for a median period of 33.3 months with tumor recurrence in 6 patients and death in 3. Conclusions: SPNP is not a rare tumor of low-grade malignancy, it mostly occurs in young females. Surgical resection is curative and most of these patients have good prognosis.",
        "keywords": [
            "Diagnosis",
            "Prognosis",
            "Retrospective studies",
            "Solid-pseudopapillary neoplasm of the pancreas"
        ],
        "venue": "Chinese Journal of Gastroenterology",
        "year": 2009,
        "id": "t64AF0tr"
    },
    "7sMqvw29": {
        "authors": [
            {
                "name": "Yuling Sun",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Shengyong Yin",
                "org": "Key Lab of Combined Multi-organ Transplantation"
            },
            {
                "name": "Haiyang Xie",
                "org": "Key Lab of Combined Multi-organ Transplantation"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Lab of Combined Multi-organ Transplantation"
            },
            {
                "name": "Yan Wang",
                "org": "Key Lab of Combined Multi-organ Transplantation"
            },
            {
                "name": "Liming Wu",
                "org": "Key Lab of Combined Multi-organ Transplantation"
            },
            {
                "name": "Shusen Zheng",
                "org": "Key Lab of Combined Multi-organ Transplantation"
            }
        ],
        "title": "Immunophenotypic shift of memory CD8 T cells identifies the changes of immune status in the patients after liver transplantation",
        "abstract": "Objective: Chronic or acute rejection is a leading cause of allograft loss after solid organ transplantation and the presence of memory T cells is associated with increased propensity for allograft rejection. The purpose of this study was to investigate the correlation between immunophenotypic shift of memory CD8",
        "keywords": [
            "Immune status",
            "Immunophenotypic shift",
            "Liver transplantation",
            "Memory T cells",
            "Rejection"
        ],
        "venue": "Scandinavian Journal of Clinical and Laboratory Investigation",
        "year": 2009,
        "id": "7sMqvw29"
    },
    "JYNzVFJ0": {
        "authors": [
            {
                "name": "Weilin Wang",
                "org": "Department of Hepatobiliary and Pancreatic Surgery, First Affiliated Hospital, Zhejiang University School of Medicine"
            },
            {
                "name": "Feng Zhu",
                "org": "Department of Hepatobiliary and Pancreatic Surgery, First Affiliated Hospital, Zhejiang University School of Medicine"
            },
            {
                "name": "Shuqian Wang",
                "org": "Department of Hepatobiliary and Pancreatic Surgery, First Affiliated Hospital, Zhejiang University School of Medicine"
            },
            {
                "name": "Jianfeng Wei",
                "org": "Department of Hepatobiliary and Pancreatic Surgery, First Affiliated Hospital, Zhejiang University School of Medicine"
            },
            {
                "name": "Changku Jia",
                "org": "Department of Hepatobiliary and Pancreatic Surgery, First Affiliated Hospital, Zhejiang University School of Medicine"
            },
            {
                "name": "Yuanbiao Zhang",
                "org": "Department of Hepatobiliary and Pancreatic Surgery, First Affiliated Hospital, Zhejiang University School of Medicine"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Hepatobiliary and Pancreatic Surgery, First Affiliated Hospital, Zhejiang University School of Medicine"
            },
            {
                "name": "Haiyang Xie",
                "org": "Department of Hepatobiliary and Pancreatic Surgery, First Affiliated Hospital, Zhejiang University School of Medicine"
            },
            {
                "name": "Shusen Zheng",
                "org": "Department of Hepatobiliary and Pancreatic Surgery, First Affiliated Hospital, Zhejiang University School of Medicine"
            }
        ],
        "title": "HSG provides antitumor efficacy on hepatocellular carcinoma both in vitro and in vivo",
        "abstract": "Hyperplasia suppressor gene (HSG) is a novel gene that markedly suppresses the mitogenetic stimuli or injury mediated by vascular smooth muscle cell proliferation. Herein we provide experimental evidence to show that HSG can also play a key role in tumor proliferation. Down-regulation of HSG protein in hepatocellular carcinoma tissues compared to adjacent tissues. Overexpression of HSG suppressed the growth of liver cancer cell lines, resulted in cell cycle arrest in the G0/G1 phase, increased expression of the cyclin dependent kinase inhibitors (CKIs), and reduced expression of proliferating cell nuclear antigen (PCNA). It also showed that adenovirus-mediated HSG overexpression induced apoptosis. Up-regulation of HSG by adenovirus also significantly suppressed the growth of subcutaneous tumors in nude mice both ex vivo and in vivo. Collectively, our data suggest that HSG is a potential therapy for tumors and possibly other proliferative diseases as well and it has antitumor efficacy on hepatocellular carcinoma by using adenovirus vectors, which may be a new therapeutic target for liver cancer prevention.",
        "keywords": [
            ""
        ],
        "venue": "Oncology Reports",
        "year": 2010,
        "id": "JYNzVFJ0"
    },
    "UWNLcW2M": {
        "authors": [
            {
                "name": "Xiangmin Shen",
                "org": ""
            },
            {
                "name": "Liming Tan",
                "org": ""
            },
            {
                "name": "Yunhai Liu",
                "org": ""
            },
            {
                "name": "Hainan Zhang",
                "org": ""
            },
            {
                "name": "Chunyu Wang",
                "org": ""
            },
            {
                "name": "Qidong Yang",
                "org": ""
            },
            {
                "name": "Qing Huang",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Zhenyu Tang",
                "org": ""
            }
        ],
        "title": "Neuroprotective role of edaravone and the effects of endoplasmic reticulum stress in an adult rat model of focal cerebral ischemia/reperfusion",
        "abstract": "BACKGROUND: Endoplasmic reticulum (ER) stress impairs ER functions and leads to the accumulation of unfolded or misfolded proteins in the ER lumen. ER stress-induced cell death plays an important role in cerebral ischemia. Edaravon (3-methyl-1-phenyl-2-pyrazolin-5-one) is a potent and novel scavenger of free radicals that inhibit delayed neuronal death, as demonstrated by in vitro and animal studies. However, its effect on ER stress and induced neuronal apoptosis in a rat model of brief middle cerebral artery occlusion remains unclear. OBJECTIVE: To explore the effects of edaravone on the expression of ER stress-related factors and neuronal apoptosis, based on the hypothesis that edaravone influences ER stress in a rat model of cerebral ischemia/reperfusion. DESIGN, TIME AND SETTING: A randomized, controlled, animal study was performed at the Laboratory of Department of Neurology, Xiangya Hospital and the Department of Laboratory Animals, Xiangya Medical College, Central South University in China from June 2005 to May 2006. MATERIALS: Edaravone was purchased from Simcere Pharmaceutical Group, China. METHODS: A total of 216 adult, male, Sprague Dawley rats were randomly assigned to sham-surgery, model and edaravone groups, with 72 rats in each group. Brief middle cerebral artery occlusion was established in the model and edaravone groups. In addition, the edaravone group rats were injected with 3 mg/kg edaravone through the tail vein. MAIN OUTCOME MEASURES: RNA-dependent protein kinase-like endoplasmic reticulum eukaryotic translation initiation factor 2\u03b1 kinase (PERK) and C/EBP homology protein (CHOP) mRNA expression in the ischemic parietal cortex was determined by reverse transcription-polymerase chain reaction; phosphorylated PERK and CHOP protein expression was detected by immunohistochemistry; neuronal apoptosis was detected by TdT-mediated-dUTP nick end labeling. RESULTS: Neurological deficit scores were significantly reduced in the edaravone group compared to the model group at 12, 24, and 72 hours following reperfusion (P < 0.05). In addition, PERK and CHOP mRNA as well as phosphorylated PERK and CHOP protein expression were significantly reduced in the edaravone group compared to the model group at 1, 3, and 6 hours following reperfusion (P < 0.05, P < 0.01). CHOP mRNA expression was decreased in the edaravone group compared to the model group at 3, 6, 12, and 24 hours following reperfusion (P < 0.01), while CHOP protein expression was less than the model group at 6, 12, and 24 hours following reperfusion (P < 0.05). CONCLUSION: Edaravone treatment resulted in decreased PERK and CHOP expression following ischemia/reperfusion, as well as reduced neuronal apoptosis. Edaravone exhibited a neuroprotective role by inhibiting endoplasmic reticulum stress.",
        "keywords": [
            "Brain injury",
            "C/EBP homology protein",
            "Cerebral ischemia/reperfusion",
            "Edaravone",
            "Endoplasmic reticulum stress",
            "Neural regeneration",
            "RNA-dependent protein kinase-like endoplasmic reticulum eIF2\u03b1 kinase"
        ],
        "venue": "Neural Regeneration Research",
        "year": 2010,
        "id": "UWNLcW2M"
    },
    "Ar07Zv84": {
        "authors": [
            {
                "name": "Jian Zhang",
                "org": "First Affiliated Hospital"
            },
            {
                "name": "Lin Zhou",
                "org": "First Affiliated Hospital"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "First Affiliated Hospital"
            }
        ],
        "title": "Clinical management of hepatitis B virus infection correlated with liver transplantation",
        "abstract": "BACKGROUND: As a radical cure for post-hepatitis B virus (HBV)-related liver cirrhosis and hepatocellular carcinoma, liver transplantation has been applied in many medical centers. Before the use of effective measures, hepatitis B recurrence and the existence of HBsAg(+) donors, patients with hepatitis B-related diseases are contraindicated for liver transplantation. Application of interferon, hepatitis B immunoglobulin (HBIG), and nucleotide analogues (e.g., lamivudine) has made great progress in the clinical care of HBV. However, there are still many shortcomings such as low viral suppression rate, rising expense, and the induction of HBV tyrosine-methionineaspartate-aspartate (YMDD) mutation. This article systematically reviews the current evidence that immunotherapy, conventional drug combinations, and some special fields of HBV infection correlate with liver transplantation. DATA SOURCES: Studies were identified by searching MEDLINE and PubMed for articles using the keywords \"hepatitis B virus\", \"hepatitis B vaccination\", \"lamivudine\", \"adefovir\", \"entecavir\", \"tenofovir\", \"HBV genotype\", and \"liver transplantation\" up to October 2009. Additional papers were identified by a manual search of the references from the key articles. RESULTS: Hepatitis B vaccine and human monoclonal antibody have very good clinical prospects. Compared with traditional therapies, the new medical regimens have many benefits such as boosting viral suppression rate and decreasing medical expenses. The triple therapy for YMDD mutation also has an excellent therapeutic effect and a low barrier to resistance. New nucleos(t)ide analogues (entecavir and tenofovir) eliminate virus more effectively with few adverse reactions, and may replace lamivudine or HBIG in future. CONCLUSIONS: Hepatitis B vaccine needs further largescale and rigorous randomized controlled trials to confirm its effective dose and injection frequency. Monoclonal antibody is still experimental, and the next step is to carry out the relevant animal and human studies. A consensus standard regimen for the treatment of hepatitis B should be developed. \u00a9 2010, Hepatobiliary Pancreat Dis Int. All rights reserved.",
        "keywords": [
            "Adefovir",
            "Genotype",
            "Hepatitis B immunoglobulin",
            "Hepatitis B vaccination",
            "Hepatitis B virus",
            "Lamivudine",
            "Liver transplantation"
        ],
        "venue": "Hepatobiliary and Pancreatic Diseases International",
        "year": 2010,
        "id": "Ar07Zv84"
    },
    "mjA9UgXj": {
        "authors": [
            {
                "name": "Hong Zhao",
                "org": "State Key Laboratory for Diagnosis and Treatment of Infectious Diseases"
            },
            {
                "name": "Jian-Hua Hu",
                "org": "State Key Laboratory for Diagnosis and Treatment of Infectious Diseases"
            },
            {
                "name": "Lin Zhou",
                "org": "Ministry of Public Health"
            },
            {
                "name": "Xiao Xu",
                "org": "Ministry of Public Health"
            },
            {
                "name": "Jian Wu",
                "org": "Ministry of Public Health"
            },
            {
                "name": "Xue-Qin Meng",
                "org": "Ministry of Public Health"
            },
            {
                "name": "Jun Fan",
                "org": "State Key Laboratory for Diagnosis and Treatment of Infectious Diseases"
            },
            {
                "name": "Wei-Hang Ma",
                "org": "State Key Laboratory for Diagnosis and Treatment of Infectious Diseases"
            }
        ],
        "title": "Impact of human leukocyte antigen matching on hepatitis B virus recurrence after liver transplantation",
        "keywords": [
            "Hepatitis B virus",
            "Human leukocyte antigen",
            "Liver transplantation",
            "Recurrence"
        ],
        "venue": "Hepatobiliary and Pancreatic Diseases International",
        "year": 2010,
        "id": "mjA9UgXj"
    },
    "erzlZ7bT": {
        "authors": [
            {
                "name": "Jun Cheng",
                "org": "Department of Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Surgery"
            },
            {
                "name": "Qin-Fen Xie",
                "org": "Department of Surgery"
            },
            {
                "name": "Hai-Yang Xie",
                "org": "Department of Surgery"
            },
            {
                "name": "Xu-Yong Wei",
                "org": "Department of Surgery"
            },
            {
                "name": "Feng Gao",
                "org": "Department of General Surgery"
            },
            {
                "name": "Chun-Yang Xing",
                "org": "Department of Surgery"
            },
            {
                "name": "Xiao Xu",
                "org": "Department of Surgery"
            },
            {
                "name": "Lan-Juan Li",
                "org": "State Key Laboratory of Infectious Diseases"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Department of Surgery"
            }
        ],
        "title": "The impact of miR-34a on protein output in hepatocellular carcinoma HepG2 cells",
        "abstract": "MicroRNAs are small non-coding RNA molecules that play essential roles in biological processes ranging from cell cycle to cell migration and invasion. Accumulating evidence suggests that miR-34a, as a key mediator of p53 tumor suppression, is aberrantly expressed in human cancers. In the present study, we aimed to explore the precise biological role of miR-34a and the global protein changes in HCC cell line HepG2 cells transiently transfected with miR-34a. Transfection of miR-34a into HepG2 cells caused suppression of cell proliferation, inhibition of cell migration and invasion. It also induced an accumulation of HepG2 cells in G1 phase. Among 116 protein spots with differential expression separated by 2-DE method, 34 proteins were successfully identified by MALDI-TOF/TOF analysis. Of these, 15 down-regulated proteins may be downstream targets of miR-34a. Bioinformatics analysis produced a protein-protein interaction network, which revealed that the p53 signaling pathway and cell cycle pathway were two major hubs containing most of the proteins regulated by miR-34a. Cytoskeletal proteins such as LMNA, GFAP, MACF1, ALDH2, and LOC100129335 are potential targets of miR-34a. In conclusion, abrogation of miR-34a function could cause downstream molecules to switch on or off, leading to HCC development. \u00a9 2010 Wiley-VCH Verlag GmbH & Co. KGaA.",
        "keywords": [
            ""
        ],
        "venue": "Proteomics",
        "year": 2010,
        "id": "erzlZ7bT"
    },
    "K2sgsTWd": {
        "authors": [
            {
                "name": "Jun Cheng",
                "org": "Department of Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Surgery"
            },
            {
                "name": "Qin-Fen Xie",
                "org": "Department of Surgery"
            },
            {
                "name": "Hai-Yang Xie",
                "org": "Department of Surgery"
            },
            {
                "name": "Xu-Yong Wei",
                "org": "Department of Surgery"
            },
            {
                "name": "Feng Gao",
                "org": "Department of General Surgery"
            },
            {
                "name": "Chun-Yang Xing",
                "org": "Department of Surgery"
            },
            {
                "name": "Xiao Xu",
                "org": "Department of Surgery"
            },
            {
                "name": "Lan-Juan Li",
                "org": "State Key Laboratory of Infectious Diseases"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Department of Surgery"
            }
        ],
        "title": "The impact of miR-34a on protein output in hepatocellular carcinoma HepG2 cells",
        "abstract": "MicroRNAs are small non-coding RNA molecules that play essential roles in biological processes ranging from cell cycle to cell migration and invasion. Accumulating evidence suggests that miR-34a, as a key mediator of p53 tumor suppression, is aberrantly expressed in human cancers. In the present study, we aimed to explore the precise biological role of miR-34a and the global protein changes in HCC cell line HepG2 cells transiently transfected with miR-34a. Transfection of miR-34a into HepG2 cells caused suppression of cell proliferation, inhibition of cell migration and invasion. It also induced an accumulation of HepG2 cells in G1 phase. Among 116 protein spots with differential expression separated by 2-DE method, 34 proteins were successfully identified by MALDI-TOF/TOF analysis. Of these, 15 down-regulated proteins may be downstream targets of miR-34a. Bioinformatics analysis produced a protein-protein interaction network, which revealed that the p53 signaling pathway and cell cycle pathway were two major hubs containing most of the proteins regulated by miR-34a. Cytoskeletal proteins such as LMNA, GFAP, MACF1, ALDH2, and LOC100129335 are potential targets of miR-34a. In conclusion, abrogation of miR-34a function could cause downstream molecules to switch on or off, leading to HCC development. \u00a9 2010 Wiley-VCH Verlag GmbH & Co. KGaA.",
        "keywords": [
            "Biomedicine",
            "Cell cycle",
            "Hepatocellular carcinoma",
            "MicroRNA",
            "miR-34a"
        ],
        "venue": "Proteomics",
        "year": 2010,
        "id": "K2sgsTWd"
    },
    "2cgVJbez": {
        "authors": [
            {
                "name": "Jiang Zhu",
                "org": ""
            },
            {
                "name": "Yu Yang",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Ming Jiang",
                "org": ""
            },
            {
                "name": "Mei Hou",
                "org": ""
            }
        ],
        "title": "A long-term follow-up of the imatinib mesylate treatment for the patients with recurrent gastrointestinal stromal tumor (GIST): The liver metastasis and the outcome",
        "abstract": "Background: About 80% of patients with GIST would experience tumor recurrence or metastasis after radical resection. The most common site of the metastasis is the liver. Imatinib mesylate has been proved effective for advanced GIST. The present study was designed to further observe the effectiveness of the imatinib mesylate treatment on the recurrent GIST and the correlation between the liver metastasis and the outcome.Methods: Forty-two patients who had recurrent GIST after the first radical resection were enrolled. According to the recurrent sites, the patients were divided into 3 groups: group LG (recurrent liver GISTs), group AG (recurrent abdominal GISTs) and group ALG (recurrent abdominal and liver GISTs). All the patients were given imatinib mesylate at an initial dose of 400 mg per day. Their clinical data was prospectively collected. A follow-up over 3 years was conducted. Tumor response, time to progression and survival were evaluated.Results: The long-term Imatinib mesylate treatment was safe and well tolerated. At a median follow-up time for 39.5 months, the 3-year survival rate was 66.7%. Median TTP and OS were 37 months (95% CI: 28.2~45.8 months) and 48 months (95% CI: 37.0~58.9 months), respectively. There was no statistical difference in tumor response among the 3 groups. The similar TTP (P = 0.291) and OS (P = 0.160) were observed in the 3 groups.Conclusions: The imatinib mesylate treatment could prolong the survival of the patients who have recurrent GIST after the radical surgery in spite of an existence of the liver metastasis. Survival was not significantly affected by liver metastasis when imatinib mesylate was warranted. \u00a9 2010 Zhu et al; licensee BioMed Central Ltd.",
        "keywords": [
            ""
        ],
        "venue": "BMC Cancer",
        "year": 2010,
        "id": "2cgVJbez"
    },
    "7osX1PfS": {
        "authors": [
            {
                "name": "Li-Ming Jin",
                "org": ""
            },
            {
                "name": "Yuan-Xing Liu",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Hai-Yang Xie",
                "org": ""
            },
            {
                "name": "Xiao-Wen Feng",
                "org": ""
            },
            {
                "name": "Hui Li",
                "org": ""
            },
            {
                "name": "Shu-Sen Zheng",
                "org": ""
            }
        ],
        "title": "Ischemic preconditioning attenuates morphological and biochemical changes in hepatic ischemia/reperfusion in rats",
        "abstract": "Objective: Ischemic preconditioning (IPC) has been gradually introduced into clinical liver surgery and transplantation in recent years. However, the protective effects of IPC on hepatic warm ischemia/reperfusion (I/R) injury and the potential mechanisms involved are not fully understood. We aimed to evaluate whether the reduction of apoptotic sinusoidal endothelial cells (SECs), induced by IPC, contributes to its protective effect. Methods: Male Wistar rats were randomized into three experimental groups: the continuous clamping group underwent 60 min of 70% hepatic ischemia; the IPC group received 10 min ischemia followed by 10 min reperfusion prior to ischemia, and the sham control (sham) underwent a sham operation without ischemia. Hepatocyte and SEC apoptosis, liver necrotic areas and the levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), hyaluronic acid, tumor necrosis factor, myeloperoxidase (MPO) and malondialdehyde were determined. Expression of cysteine-aspartic acid protease-3 (caspase-3) in hepatocytes and SECs was also investigated. Furthermore, the hepatic leukocyte infiltration was assessed by intravital fluorescence microscopy. Results: IPC exhibited a significant alleviation of their postischemic liver function. Serum AST, ALT and tissue MPO were significantly decreased by IPC, and the degree of hepatocyte and SEC apoptosis was significantly inhibited, as shown by the decreased numbers of adherent leukocytes. Conclusions: IPC attenuates hepatic I/R injury by the reduction of leukocyte infiltration, the reduction hepatic enzymatic leakage and the depression of apoptotic cells. SECs are more sensitive to apoptosis induced by warm I/R injury compared to hepatocytes. \u00a9 2010 S. Karger AG.",
        "keywords": [
            "Apoptosis",
            "Ischemia reperfusion injury",
            "Ischemic preconditioning",
            "Leukocyte",
            "Liver"
        ],
        "venue": "Pathobiology",
        "year": 2010,
        "id": "7osX1PfS"
    },
    "ut99HBFs": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Green Chemistry and Technology"
            },
            {
                "name": "Lili Lin",
                "org": "Key Laboratory of Green Chemistry and Technology"
            },
            {
                "name": "Wentao Wang",
                "org": "Key Laboratory of Green Chemistry and Technology"
            },
            {
                "name": "Jie Ji",
                "org": "Key Laboratory of Green Chemistry and Technology"
            },
            {
                "name": "Xiaohua Liu",
                "org": "Key Laboratory of Green Chemistry and Technology"
            },
            {
                "name": "Xiaoming Feng",
                "org": "Key Laboratory of Green Chemistry and Technology"
            }
        ],
        "title": "Highly enantioselective Michael addition of malonates to \u03b2,\u03b3-unsaturated \u03b1-ketoesters catalyzed by chiral N,N\u2032-dioxide-Yttrium(iii) complexes with convenient procedure",
        "abstract": "Highly enantioselective Michael addition of malonates to \u03b2,\u03b3-unsaturated \u03b1-ketoesters has been promoted by chiral N,N\u2032-dioxide-Yttrium(iii) complexes, providing the corresponding products in excellent yields with 94-99% ee values. \u00a9 2010 The Royal Society of Chemistry.",
        "keywords": [
            ""
        ],
        "venue": "Chemical Communications",
        "year": 2010,
        "id": "ut99HBFs"
    },
    "SKJTYVQe": {
        "authors": [
            {
                "name": "Xiao Xu",
                "org": "Department of Hepatobiliary and Pancreatic Surgery, Zhejiang University School of Medicine"
            },
            {
                "name": "Qi Ling",
                "org": "Department of Hepatobiliary and Pancreatic Surgery, Zhejiang University School of Medicine"
            },
            {
                "name": "Qiang Wei",
                "org": "Department of Hepatobiliary and Pancreatic Surgery, Zhejiang University School of Medicine"
            },
            {
                "name": "Jian Wu",
                "org": "Department of Hepatobiliary and Pancreatic Surgery, Zhejiang University School of Medicine"
            },
            {
                "name": "Feng Gao",
                "org": "Department of Hepatobiliary and Pancreatic Surgery, Zhejiang University School of Medicine"
            },
            {
                "name": "Zeng-Lei He",
                "org": "Department of Hepatobiliary and Pancreatic Surgery, Zhejiang University School of Medicine"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Hepatobiliary and Pancreatic Surgery, Zhejiang University School of Medicine"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Department of Hepatobiliary and Pancreatic Surgery, Zhejiang University School of Medicine"
            }
        ],
        "title": "An effective model for predicting acute kidney injury after liver transplantation",
        "keywords": [
            "Acute kidney injury",
            "Complications",
            "Liver transplantation",
            "Prognosis",
            "Risk factors"
        ],
        "venue": "Hepatobiliary and Pancreatic Diseases International",
        "year": 2010,
        "id": "SKJTYVQe"
    },
    "iw5CIBXM": {
        "authors": [
            {
                "name": "Bingwen Zou",
                "org": ""
            },
            {
                "name": "Yong Xu",
                "org": ""
            },
            {
                "name": "Tao Li",
                "org": ""
            },
            {
                "name": "Wenhui Li",
                "org": ""
            },
            {
                "name": "Bangxian Tang",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Lu Li",
                "org": ""
            },
            {
                "name": "Yongmei Liu",
                "org": ""
            },
            {
                "name": "Jiang Zhu",
                "org": ""
            },
            {
                "name": "Meijuan Huang",
                "org": ""
            },
            {
                "name": "Jin Wang",
                "org": ""
            },
            {
                "name": "Li Ren",
                "org": ""
            },
            {
                "name": "Youlin Gong",
                "org": ""
            },
            {
                "name": "Guowei Che",
                "org": ""
            },
            {
                "name": "Lunxu Liu",
                "org": ""
            },
            {
                "name": "Mei Hou",
                "org": ""
            },
            {
                "name": "You Lu",
                "org": ""
            }
        ],
        "title": "A Multicenter Retrospective Analysis of Survival Outcome Following Postoperative Chemoradiotherapy in Non-Small-Cell Lung Cancer Patients With N2 Nodal Disease",
        "abstract": "Purpose: To retrospectively evaluate the role of postoperative chemoradiotherapy (POCRT) in patients with completely resected non-small-cell lung cancer (NSCLC) with N2 lymph node involvement. Methods and Materials: This study included 183 patients from four centers in southwest China who underwent radical section of Stage III-N2 NSCLC without any preoperative therapy. One hundred and four were treated with POCRT and 79 with postoperative chemotherapy (POCT) alone. The median radiation dose to clinical target volume (CTV) was 50 Gy (varying between 48 and 54 Gy), whereas the cycles of platinum-based chemotherapy ranged from two to six with a median of four. Results: The median duration of follow-up was 72 months. The 5-year overall survival rate (OS) was 30.5% in the POCRT group, and 14.4% in the POCT group (p = 0.007). The 5-year disease-free survival rate (DFS) was 22.2% in POCRT group and 9.3% in POCT group (p = 0.003). In a multivariate analysis, N1 nodal involvement (N1+/N2+) was associated with significantly worse OS (HR = 1.454, 95% CI, 1.012-2.087, p = 0.043) and DFS (HR = 1.685, 95% CI, 1.196-2.372, p = 0.003). Absence of radiotherapy and treatment with fewer than three cycles of chemotherapy both were poor prognostic factors for both OS and DFS. Conclusions: As compared with chemotherapy alone, adjuvant treatment with both radiotherapy and chemotherapy improves survival in patients with completely resected Stage III-N2 nodal disease in NSCLC. Future study of treatment modality with radiotherapy and chemotherapy is warranted, especially focusing on both N1 and N2 nodal status. \u00a9 2010 Elsevier Inc. All rights reserved.",
        "keywords": [
            "N2",
            "NSCLC",
            "Operation",
            "Postoperative chemoradiotherapy",
            "Radiotherapy"
        ],
        "venue": "International Journal of Radiation Oncology Biology Physics",
        "year": 2010,
        "id": "iw5CIBXM"
    },
    "VhhZCO9U": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Department of Prosthodontics"
            },
            {
                "name": "Zhongchun Tong",
                "org": "Department of Endodontics"
            },
            {
                "name": "Guofeng Wu",
                "org": "Department of Prosthodontics"
            },
            {
                "name": "Zhihong Feng",
                "org": "Department of Prosthodontics"
            },
            {
                "name": "Shizhu Bai",
                "org": "Department of Prosthodontics"
            },
            {
                "name": "Yan Dong",
                "org": "Department of Prosthodontics"
            },
            {
                "name": "Longxing Ni",
                "org": "Department of Endodontics"
            },
            {
                "name": "Yimin Zhao",
                "org": "Department of Prosthodontics"
            }
        ],
        "title": "Parylene coating hinders Candida albicans adhesion to silicone elastomers and denture bases resin",
        "abstract": "Objective: To investigate whether parylene coatings over denture bases and silicone elastomers can effectively reduce Candida albicans adhesion and thus to decrease the incidence of denture stomatitis. Design: Specimens of silicone elastomers A-2186 or lucitone 199 resin were prepared, and the measurements of contact angle, assay of XTT reduction and cell count of C. albicans adhesion were taken before and after parylene treatment. Furthermore, morphology of C. albicans adhesion for 48 h was observed by scanning electron microscope (SEM), and C. albicans adhesion for 4 h was illustrated by confocal scanning laser microscopy (CLSM) in combination with fluorescent dyes FUN-1 and Concanavalin A. Result: There was a statistical difference between mean contact angles of silicone elastomer A-2186 before and after parylene coating (P < 0.05). The amount of C. albicans adhesion to the surface of silicone elastomer A-2186 and lucitone 199 resin after parylene treatment was significantly less than before parylene treatment by cells count and XTT reduction assay (P < 0.05). In SEM and CLSM analysis, C. albicans biofilm was more apt to generate on the surface of silicone elastomer A-2186 than other three groups, and more C. albicans aggregation formed on the surface of silicone elastomer A-2186 and lucitone 199 resin before parylene treatment than after parylene treatment. Conclusion: Parylene coating reduced C. albicans adhesion and aggregation on the surface of silicone elastomer A-2186 and lucitone 199 resin, and improved the wettability of silicone elastomer A-2186. \u00a9 2010 Elsevier B.V. All rights reserved.",
        "keywords": [
            "Adhesion",
            "Biofilm",
            "Candida albicans",
            "Contact angle",
            "Parylene"
        ],
        "venue": "Archives of Oral Biology",
        "year": 2010,
        "id": "VhhZCO9U"
    },
    "oBs87vKE": {
        "authors": [
            {
                "name": "Youling Gong",
                "org": "Department of Thoracic Oncology, Cancer Center"
            },
            {
                "name": "Shichao Wang",
                "org": "Radiation and Physics Center, Cancer Center"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Thoracic Oncology, Cancer Center"
            },
            {
                "name": "Yongmei Liu",
                "org": "Department of Thoracic Oncology, Cancer Center"
            },
            {
                "name": "Yong Xu",
                "org": "Department of Thoracic Oncology, Cancer Center"
            },
            {
                "name": "You Lu",
                "org": "Department of Thoracic Oncology, Cancer Center"
            },
            {
                "name": "Sen Bai",
                "org": "Radiation and Physics Center, Cancer Center"
            },
            {
                "name": "Yuchuan Fu",
                "org": "Radiation and Physics Center, Cancer Center"
            },
            {
                "name": "Qingfeng Xu",
                "org": "Radiation and Physics Center, Cancer Center"
            },
            {
                "name": "Qingfeng Jiang",
                "org": "Radiation and Physics Center, Cancer Center"
            }
        ],
        "title": "Dosimetric comparison using different multileaf collimeters in intensity-modulated radiotherapy for upper thoracic esophageal cancer",
        "abstract": "Purpose: To study the impacts of multileaf collimators (MLC) width [standard MLC width of 10 mm (sMLC) and micro-MLC width of 4 mm (mMLC)] in the intensity-modulated radiotherapy (IMRT) planning for the upper thoracic esophageal cancer (UTEC).Methods and materials: 10 patients with UTEC were retrospectively planned with the sMLC and the mMLC. The monitor unites (MUs) and dose volume histogram-based parameters [conformity index (CI) and homogeneous index (HI)] were compared between the IMRT plans with sMLC and with mMLC.Results: The IMRT plans with the mMLC were more efficient (average MUs: 703.1 \u00b1 68.3) than plans with the sMLC (average MUs: 833.4 \u00b1 73.8) (p < 0.05). Also, compared to plans with the sMLC, the plans with the mMLC showed advantages in dose coverage of the planning gross tumor volume (Pgtv) (CI 0.706 \u00b1 0.056/HI 1.093 \u00b1 0.021) and the planning target volume (PTV) (CI 0.707 \u00b1 0.029/HI 1.315 \u00b1 0.013) (p < 0.05). In addition, the significant dose sparing in the D",
        "keywords": [
            ""
        ],
        "venue": "Radiation Oncology",
        "year": 2010,
        "id": "oBs87vKE"
    },
    "SCPh2OZn": {
        "authors": [
            {
                "name": "Yufu Ye",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Xiaojun Xie",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Jiwei Yu",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Haiyang Xie",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Guoping Jiang",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Xiaobo Yu",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Wenjin Zhang",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Jian Wu",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Shusen Zheng",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            }
        ],
        "title": "Involvement of Th17 and Th1 effector responses in patients with hepatitis B",
        "keywords": [
            "Hepatitis B",
            "IL-17",
            "Interferon-gamma",
            "Regulatory T cells"
        ],
        "venue": "Journal of Clinical Immunology",
        "year": 2010,
        "id": "SCPh2OZn"
    },
    "vZ55EeJy": {
        "authors": [
            {
                "name": "Sheng Yan",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Li-Ming Jin",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Yuan-Xing Liu",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Hai-Yang Xie",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation"
            }
        ],
        "title": "Outcomes and mechanisms of ischemic preconditioning in liver transplantation",
        "abstract": "BACKGROUND: Liver transplantation is so far the most effective therapeutic modality for end-stage liver diseases, but ischemia/reperfusion (I/R) injury represents a critical barrier to liver transplantation. Primary graft dysfunction and small-for-size syndrome are closely associated with I/R injury. Ischemic preconditioning (IPC) is defined as a brief period of liver ischemia followed by reperfusion, and has demonstrated protections against a prolonged I/R injury and improved the capacity of regeneration. The article aimed to review IPC literatures for the understanding of the effects of IPC on I/R injury involving in the procurement of donor liver and protective mechanisms. DATA SOURCES: A literature search of MEDLINE and Web of Science databases using \"liver transplantation\", \"liver regeneration\", \"hepatectomy\", \"ischemia/reperfusion\" and \"ischemic preconditioning\" was performed, and then a large amount of related data was collected. RESULTS: The literature search provided a huge amount of evidence for the protective effects of IPC on I/R injury in liver transplantation, including reduction of blood loss in hepatectomy, intraoperative hemodynamic stability and its significant role in liver regeneration. The mechanism involves in balancing inflammatory cytokines, enhancing energy status and mitigating microcirculatory disturbance. CONCLUSION: IPC plays an essential role in hepatectomy before and after harvest of living donor liver and implantation of liver graft. \u00a9 2010, Hepatobiliary Pancreat Dis Int.",
        "keywords": [
            "Hepatectomy",
            "Ischemia/reperfusion injury",
            "Ischemic preconditioning",
            "Liver regeneration",
            "Liver transplantation"
        ],
        "venue": "Hepatobiliary and Pancreatic Diseases International",
        "year": 2010,
        "id": "vZ55EeJy"
    },
    "ikWhhfys": {
        "authors": [
            {
                "name": "Yuan-Xing Liu",
                "org": "Department of Surgery"
            },
            {
                "name": "Li-Ming Jin",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Hai-Yang Xie",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Guo-Ping Jiang",
                "org": "Department of Surgery"
            },
            {
                "name": "Hui Chen",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Department of Surgery"
            }
        ],
        "title": "Sirolimus attenuates reduced-size liver ischemia-reperfusion injury but impairs liver regeneration in rats",
        "abstract": "Background: Evidence has suggested that immunosuppressive drugs impact ischemia-reperfusion injury. Aims: The purpose of the present study was to evaluate the effect of sirolimus on hepatic injury and regeneration in a rat reduced-size liver ischemia-reperfusion model. Methods: Using a newly developed rat reduced-size liver ischemia-reperfusion injury model, the effects of sirolimus were evaluated by assessing liver cell apoptosis and aspartate aminotransferase, myeloperoxidase, and malondialdehyde levels. In addition, liver regeneration after sirolimus treatment was evaluated by measuring liver weight resumption and by the histological examination of bromodeoxyuridine and proliferating cell nuclear antigen expression. Results: Sirolimus significantly decreased liver cell apoptosis as well as tissue myeloperoxidase and malondialdehyde levels, but impaired postischemic liver regeneration. Ischemia-reperfusion-induced elevation of aspartate aminotransferase serum levels was significantly decreased by sirolimus. Conclusions: Despite an impairment of postischemic liver proliferation, sirolimus demonstrated beneficial amelioration of ischemia-reperfusion-induced liver injury in a reduced-size liver model in rats. \u00a9 2009 Springer Science+Business Media, LLC.",
        "keywords": [
            "Ischemia-reperfusion injury",
            "Reduced-size",
            "Regeneration",
            "Sirolimus"
        ],
        "venue": "Digestive Diseases and Sciences",
        "year": 2010,
        "id": "ikWhhfys"
    },
    "rkll9JVd": {
        "authors": [
            {
                "name": "Li-Ming Wu",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Feng Zhang",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Zhe Yang",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Hai-Yang Xie",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            }
        ],
        "title": "Predictive value of CpG island methylator phenotype for tumor recurrence in hepatitis B virus-associated hepatocellular carcinoma following liver transplantation",
        "abstract": "Background: CpG island methylator phenotype (CIMP), in which multiple genes concordantly methylated, has been demonstrated to be associated with progression, recurrence, as well as overall survival in some types of cancer.Methods: We examined the promoter methylation status of seven genes including P16, CDH1, GSTP1, DAPK, XAF1, SOCS1 and SYK in 65 cases of HCC treated with LT by methylation-specific PCR. CIMP+ was defined as having three or more genes that are concordantly methylated. The relationship between CIMP status and clinicopathological parameters, as well as tumor recurrence was further analyzed.Results: CIMP+ was more frequent in HCC with AFP > 400 ng/ml than those with AFP \u2264 400 ng/ml (P = 0.017). In addition, patients with CIMP+ were prone to have multiple tumor numbers than those with CIMP- (P = 0.007). Patients with CIMP+ tumors had significantly worse recurrence-free survival (RFS) than patients with CIMP-tumors by Kaplan-Meier estimates (P = 0.004). Multivariate analysis also revealed that CIMP status might be a novel independent prognostic factor of RFS for HCC patients treated with LT (HR: 3.581; 95% CI: 1.473-8.710, P = 0.005).Conclusion: Our results suggested that CIMP could serve as a new prognostic biomarker to predict the risk of tumor recurrence in HCC after transplantation. \u00a9 2010 Wu et al; licensee BioMed Central Ltd.",
        "keywords": [
            ""
        ],
        "venue": "BMC Cancer",
        "year": 2010,
        "id": "rkll9JVd"
    },
    "AQ4RrIhK": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Jun-Liang Fu",
                "org": ""
            },
            {
                "name": "Yin-Ying Lu",
                "org": ""
            },
            {
                "name": "Bao-Yun Fu",
                "org": ""
            },
            {
                "name": "Chun-Ping Wang",
                "org": ""
            },
            {
                "name": "Lin-Jing An",
                "org": ""
            },
            {
                "name": "Xin-Zhen Wang",
                "org": ""
            },
            {
                "name": "Zhen Zeng",
                "org": ""
            },
            {
                "name": "Chun-Bao Zhou",
                "org": ""
            },
            {
                "name": "Yong-Ping Yang",
                "org": ""
            },
            {
                "name": "Fu-Sheng Wang",
                "org": ""
            }
        ],
        "title": "Regulatory T cells are associated with post-cryoablation prognosis in patients with hepatitis B virus-related hepatocellular carcinoma",
        "abstract": "Background: We carried out this study to evaluate the association between regulatory T cells (Treg) and prognosis and progression after cryoablation in patients with hepatitis-B virus-related hepatocellular carcinoma. Methods: Peripheral Treg frequency in 111 patients with hepatocellular carcinoma (HCC) was detected by flow cytometry. Treg frequency and function were re-examined during patient follow up. A possible association between Treg and \u03b1-fetoprotein (AFP) was also analyzed, and the distribution of resident CD4",
        "keywords": [
            "Cryoablation",
            "Hepatocellular carcinoma",
            "Prognosis",
            "Regulatory T cell"
        ],
        "venue": "Journal of Gastroenterology",
        "year": 2010,
        "id": "AQ4RrIhK"
    },
    "0VAdDrLa": {
        "authors": [
            {
                "name": "Hong Wang",
                "org": "Department of Oncology"
            },
            {
                "name": "Guang-Xian Liu",
                "org": "Department of Oncology"
            },
            {
                "name": "Hai-Long Zhuo",
                "org": "Department of Oncology"
            },
            {
                "name": "Wen-Lin Bai",
                "org": "Department of Oncology"
            },
            {
                "name": "Yu Wu",
                "org": "Department of Oncology"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Oncology"
            },
            {
                "name": "Min Lou",
                "org": "Department of Oncology"
            },
            {
                "name": "Zhen Zeng",
                "org": "Department of Oncology"
            },
            {
                "name": "Xiu-Juan Chang",
                "org": "Department of Oncology"
            },
            {
                "name": "Jian-Ming Xu",
                "org": "Department of Oncology"
            }
        ],
        "title": "Endothelial progenitor cells carrying hIFN-\u03b3 enhances efficacy of cancer maintenance therapy after chemotherapy",
        "abstract": "Objective: To observe the efficacy of endothelial progenitor cells carrying hIFN-\u03b3 (EPCs-hIFN-\u03b3) in cancer maintenance therapy after chemotherapy. Methods: MTT was used to examine the inhibitory effects of hIFN-\u03b3 and/or C225 against colorectal cancer LoVo cells after treatment with CPT-11. The in vivo inhibitory effects of EPCs-hIFN-\u03b3 and/or C225 on LoVo tumors and their effects on survival of LoVo tumor-bearing nude mice were investigated after mice had been treated with CPT-11. Results: In vitro, hIFN-\u03b3 and/or C225 further inhibited the growth of cancer cells after CFT-11 treatment. In vivo, after 50 mg/kg CPT-11 treatment, EPCs-hIFN-\u03b3, C225 and EPCs-hIFN-\u03b3 + C225 inhibited the growth of tumors in LoVo tumor-bearing nude mice (mean tumor volumes: [2024.28 \u00b1 1048.40] mm ",
        "keywords": [
            "Colorectal neoplasmas",
            "Endothelial progenitor cell",
            "hIFN-\u03b3",
            "Immunotherapy"
        ],
        "venue": "Chinese Journal of Cancer Biotherapy",
        "year": 2010,
        "id": "0VAdDrLa"
    },
    "K9GjA0Jl": {
        "authors": [
            {
                "name": "Shuang Zhu",
                "org": "School of Life Science and Biopharmacology"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Life Science and Biopharmacology"
            },
            {
                "name": "Kai-Hong Huang",
                "org": "School of Life Science and Biopharmacology"
            },
            {
                "name": "Hong-Liang Huang",
                "org": "School of Life Science and Biopharmacology"
            },
            {
                "name": "Xiao-Xia Gao",
                "org": "School of Pharmacy"
            },
            {
                "name": "Chang-Qing Zeng",
                "org": "School of Chinese Materia Medica"
            }
        ],
        "title": "ITS sequence analysis of Uncaria hirsute and Uncaria sessili frutus",
        "abstract": "Objective In order to clarify the phylogenetic relationships between the different species of Uncaria Schred, genetic analysis was carried out for Uncaria hirsute and U. sessilifructus by using the rDNA ITS sequence as molecular marker. Methods Total DNA was extracted with modified CTAB method and thereby rDNA ITS regions were amplified with common primers. The rDNA ITS amplicon was characterized by RFLP, sequencing and phylogenetic analyses using PAUP by maximum parsimony. Results The Msp I - and Hae III -based RFLP patterns of rDNA ITS from 17. hirsute and U. sessilifrctus were obtained, where the resultant entire sequences of rDNA ITS region were both 718 bp. Conclusion Based on molecular biology methods of rDNA ITS sequence analysis, accurate molecular identification could be performed on traditional Chinese medicinal material plants in Uncaria Schred and provide molecular evidence for taxonomy and identification of different species in Uncaria Schred.",
        "keywords": [
            "ITS sequence",
            "Uncaria hirsute Havil.",
            "Uncaria sessilifructus Roxb."
        ],
        "venue": "Chinese Traditional and Herbal Drugs",
        "year": 2010,
        "id": "K9GjA0Jl"
    },
    "zEQy8v5X": {
        "authors": [
            {
                "name": "Aibin Zhang",
                "org": ""
            },
            {
                "name": "Yan Wang",
                "org": ""
            },
            {
                "name": "Zhou Ye",
                "org": ""
            },
            {
                "name": "Haiyang Xie",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Shusen Zheng",
                "org": ""
            }
        ],
        "title": "Mechanism of TNF-\u03b1-induced migration and hepatocyte growth factor production in human mesenchymal stem cells",
        "abstract": "Accumulating evidence suggests that mesenchymal stem cells (MSCs) may decrease destructive inflammation and reduce tissue loss. Tumor necrosis factor-\u03b1 (TNF-\u03b1) plays a central role in induction of proinflammatory signaling and paradoxically activates intracellular antiinflammatory survival pathways. In this study, we investigated whether TNF-\u03b1 could induce a chemotactic effect on human MSCs and stimulate their production of anti-inflammatory factors in vitro, as well as determined mechanisms that mediated this effect. Migration assays demonstrated that TNF-\u03b1 had a chemotactic effect on MSCs. TNF-\u03b1 increased both hepatocyte growth factor (HGF) mRNA expression in MSCs and HGF secretion in conditioned medium. These effects were dependent on the p38 MAPK and PI3K/Akt, but not JNK and ERK signaling pathways. Furthermore, these effects were inhibited by a specific neutralizing antibody to TNF receptor II, but not TNF receptor I. We conclude that TNF-\u03b1 can enhance human MSCs migration and stimulate their production of HGF. These effects are mediated via a specific TNF receptor and signaling pathways. \u00a9 2010 Wiley-Liss, Inc.",
        "keywords": [
            "Anti-inflammatory cytokine",
            "Cell migration",
            "Hepatocyte growth factor",
            "Mesenchymal stem cells",
            "TNF-\u03b1"
        ],
        "venue": "Journal of Cellular Biochemistry",
        "year": 2010,
        "id": "zEQy8v5X"
    },
    "bJulVmLc": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Ruifeng Zhang",
                "org": ""
            },
            {
                "name": "Lishun Wang",
                "org": ""
            },
            {
                "name": "Shaoming Shen",
                "org": ""
            },
            {
                "name": "Hiroshi Okamoto",
                "org": ""
            },
            {
                "name": "Akira Sugawara",
                "org": ""
            },
            {
                "name": "Li Xia",
                "org": ""
            },
            {
                "name": "Xiaoling Wang",
                "org": ""
            },
            {
                "name": "Naoya Noguchi",
                "org": ""
            },
            {
                "name": "Takeo Yoshikawa",
                "org": ""
            },
            {
                "name": "Akira Uruno",
                "org": ""
            },
            {
                "name": "Weiyan Yao",
                "org": ""
            },
            {
                "name": "Yaozong Yuan",
                "org": ""
            }
        ],
        "title": "Upregulation of REG I\u03b1 accelerates tumor progression in pancreatic cancer with diabetes",
        "abstract": "Diabetes is now generally accepted as a crucial event in the process of pancreatic cancer (PaC). However, molecular mechanisms underlying the relationship between diabetes and PaC are not fully understood. Regenerating gene (REG) I\u03b1 is a growth factor affecting pancreatic islet beta cells, and it has been shown to be involved in the carcinogenesis in gastrointestinal tract. It is rational to speculate that REG I\u03b1 plays a potential role in the pathogenesis of PaC with diabetes. The aim of this study was to evaluate the REG I\u03b1 protein expression profile in PaC with and without diabetes, and define the contribution of REG I\u03b1 on PaC development. We found that REG I\u03b1 protein preferentially expressed in cancerous tissues of PaC patients with diabetes by Western blot. REG I\u03b1 positive cancer cells in PaC with diabetes (n = 38) was significantly higher than that in subjects without diabetes (n = 42, p < 0.05) by immunohistochemical analysis. Furthermore, we found that overexpression of REG I\u03b1 protein in PaC cell lines resulted in accelerated cell proliferation and consequently tumor growth, both in vitro and in vivo. The findings suggest that REG I\u03b1 may act as one of the tumor promoter and contribute to the aggressive nature of PaC, especially in the subpopulation with diabetes. This study would shed new insights for understanding the molecular mechanisms underlying the link between diabetes and PaC. \u00a9 2010 UICC.",
        "keywords": [
            "diabetes",
            "pancreatic cancer",
            "REG I\u03b1"
        ],
        "venue": "International Journal of Cancer",
        "year": 2010,
        "id": "bJulVmLc"
    },
    "eAeFN0Od": {
        "authors": [
            {
                "name": "Weilin Wang",
                "org": "Key Lab of Combined Multi-organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Xiaofei Cheng",
                "org": "Key Lab of Combined Multi-organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Jianju Lu",
                "org": "Key Lab of Combined Multi-organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Jianfeng Wei",
                "org": "Key Lab of Combined Multi-organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Guanghou Fu",
                "org": "Department of Urology"
            },
            {
                "name": "Feng Zhu",
                "org": "Key Lab of Combined Multi-organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Changku Jia",
                "org": "Key Lab of Combined Multi-organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Lab of Combined Multi-organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Haiyang Xie",
                "org": "Key Lab of Combined Multi-organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Shusen Zheng",
                "org": "Key Lab of Combined Multi-organ Transplantation, Ministry of Public Health"
            }
        ],
        "title": "Mitofusin-2 is a novel direct target of p53",
        "abstract": "The tumor suppressor p53 modulates transcription of a number of target genes involved in cell cycle arrest, apoptosis, DNA repair, and other important cellular responses. Mitofusin-2 (Mfn2) is a novel suppressor of cell proliferation that may also exert apoptotic effects via the mitochondrial apoptotic pathway. Through bioinformatics analysis, we identified a p53 binding site in the Mfn2 promoter. Consistent with this, we showed that the p53 protein binds the Mfn2 promoter directly both in vitro and in vivo. Additionally, we found that Mfn2 mRNA and protein levels are up-regulated in a p53-dependent manner. Furthermore, luciferase assays revealed that the activity of the wild-type Mfn2 promoter, but not a mutated version of the promoter, was up-regulated by p53. These results indicate that Mfn2 is a novel p53-inducible target gene, which provides insight into the regulation of Mfn2 and its associated activities in the inhibition of cell proliferation, promotion of apoptosis, and modulation of tumor suppression. \u00a9 2010 Elsevier Inc.",
        "keywords": [
            "Chromatin immunoprecipitation",
            "Mfn2",
            "P53",
            "Promoter",
            "Transcription"
        ],
        "venue": "Biochemical and Biophysical Research Communications",
        "year": 2010,
        "id": "eAeFN0Od"
    },
    "hp8WIqlE": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "College of Computer Science"
            },
            {
                "name": "Min Yao",
                "org": "College of Computer Science"
            },
            {
                "name": "Yongjun Li",
                "org": "RandD Center"
            },
            {
                "name": "Chengshuo Zhang",
                "org": "College of Computer Science"
            },
            {
                "name": "Liujie Yao",
                "org": "College of Computer Science"
            }
        ],
        "title": "A new specification-based test data generation strategy for OSEK OS",
        "abstract": "Specification-based test is used to test a software application to check if it conforms to its design specification. Writing adequate test suites is very challenging and labor-intensive. Producing Specification-based tests for Real-Time Operating System (RTOS) is more challenging than for generic applications since specifications of RTOS only provide resource management mechanisms rather than specific application functionality descriptions. In this paper, we investigate whether Genetic Algorithms (GAs) can generate qualified tests for RTOS, and we present an effective GA approach with an optimization of Kuhn-Munkres maximum weighted algorithm. Experiment results demonstrate the effectiveness of our approach. It is able to generate 100% state coverage tests within 200 generations. \u00a9 2010 IEEE.",
        "keywords": [
            ""
        ],
        "venue": "Proceedings - 10th IEEE International Conference on Computer and Information Technology, CIT-2010, 7th IEEE International Conference on Embedded Software and Systems, ICESS-2010, ScalCom-2010",
        "year": 2010,
        "id": "hp8WIqlE"
    },
    "yjeGfIqy": {
        "authors": [
            {
                "name": "Xiao-Jun Xie",
                "org": "Department of Surgery"
            },
            {
                "name": "Yu-Fu Ye",
                "org": "Department of Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Surgery"
            },
            {
                "name": "Hai-Yang Xie",
                "org": "Department of Surgery"
            },
            {
                "name": "Guo-Ping Jiang",
                "org": "Department of Surgery"
            },
            {
                "name": "Xiao-Wen Feng",
                "org": "Department of Surgery"
            },
            {
                "name": "Yong He",
                "org": "Department of Surgery"
            },
            {
                "name": "Qin-Fen Xie",
                "org": "Department of Surgery"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Department of Surgery"
            }
        ],
        "title": "Th17 promotes acute rejection following liver transplantation in rats",
        "abstract": "T help cell 17 (Th17), recently identified as a new subset of CD4 ",
        "keywords": [
            "Liver transplantation",
            "Rejection",
            "Th17",
            "Transplant immunology"
        ],
        "venue": "Journal of Zhejiang University: Science B",
        "year": 2010,
        "id": "yjeGfIqy"
    },
    "RZ0ASIoW": {
        "authors": [
            {
                "name": "Zhongchun Tong",
                "org": "Department of Conservative Dentistry and Endodontics"
            },
            {
                "name": "Liping Dong",
                "org": "Department of Conservative Dentistry and Endodontics"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Prosthodontics"
            },
            {
                "name": "Rui Tao",
                "org": "Department of Conservative Dentistry and Endodontics"
            },
            {
                "name": "Longxing Ni",
                "org": "Department of Conservative Dentistry and Endodontics"
            }
        ],
        "title": "Nisin inhibits dental caries-associated microorganism in vitro",
        "abstract": "Nisin, produced by Lactococcus lactis, is an antibiotic peptide to effectively antagonize a broad spectrum of Gram-positive bacteria, and is widely used as a safe food antimicrobial agent. In the present study, we investigated whether nisin could be used as an effective antibiotic peptide against the nine common cariogenic microorganisms, and its antimicrobial activity could be affected by the ingredients of saliva in oral cavity. In the minimal inhibitory concentration (MIC) and minimal bactericide concentration (MBC) and spot-on-lawn assay, nisin displayed different MIC, MBC and antimicrobial activity against the nine tested strains. There was statistical difference between the inhibitory zone diameters of nisin against the different tested bacteria (p < 0.05), but no statistical difference between the inhibitory zone diameters of nisin dissolved in PBS and saliva (p > 0.05). Furthermore, morphology and membranes of Streptococcus sanguinis, Streptococcus mutans, Lactobacillus fermenti and Lactobacillus acidophilus with nisin treatment were observed and showed different degrees of variation by a Field Emission Scanning Electron Microscope (FE-SEM). Our findings suggested that nisin has considerable potential for prevention and treatment of dental caries. \u00a9 2010 Elsevier Inc. All rights reserved.",
        "keywords": [
            "Inhibitory zone",
            "MBC",
            "MIC",
            "Nisin",
            "Spot-on-lawn"
        ],
        "venue": "Peptides",
        "year": 2010,
        "id": "RZ0ASIoW"
    },
    "HRySs5ty": {
        "authors": [
            {
                "name": "Yin-Ying Lu",
                "org": ""
            },
            {
                "name": "Chun-Ping Wang",
                "org": ""
            },
            {
                "name": "Jian-Hui Qu",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Xiu-Juan Chang",
                "org": ""
            },
            {
                "name": "Wen-Lin Bai",
                "org": ""
            },
            {
                "name": "Yan Chen",
                "org": ""
            },
            {
                "name": "Lin-Jing An",
                "org": ""
            },
            {
                "name": "Zhen Zeng",
                "org": ""
            },
            {
                "name": "Yong-Ping Yang",
                "org": ""
            }
        ],
        "title": "Liver microvessel density in evaluating therapeutic effect of sorafenib combined with argon-helium cryoablation in treatment of advanced hepatocellular carcinoma",
        "abstract": "Objective To investigate the therapeutic effect of argon-helium cryoablation combined with sorafenib on hepatitis B-related advanced hepatocellular carcinoma (HCC) and to evaluate the role of microvessel density (MVD) in prognostic evaluation. Methods A total of 102 patients with advanced HCC were randomly divided into two groups, with 50 receiving sorafenib plus cryoablation(group S&-C) and 52 receiving only cryoablation (group C). The endpoint of the treatment was tumor progression or untolerable adverse reaction. Tumor tissues were obtained before treatment. MVD was evaluated by immunohistochemical analysis using CD34 antibody. The therapeutic effects were evaluated according to RECIST criterion every 4-6 weeks. The adverse events were observed in both groups; the therapeutic effect, overall survival time (OS), and time to progression(TTP) were compared between two groups. Results In group ScV-C, complete response (CR) was achieved in 2 patients(4%), partial response (PR) in 9 (18%), and stable disease(SD) in 22(44%), with the disease control rate(DCR) being 66%; in group C. no CR, PR in 4(7. 6%), and SD in 19(36. 5%), with the DCR being 44. 2% (P<0. 05). The overall survival (OS) and the time to progression (TTP) were significantly longer in group S&-C than in group C (12. 5 months vs 8. 6 months, 9. 6 months vs 5. 3 months; P<0.01). The mean MVD in group CR&.PR (111/0.74 mm",
        "keywords": [
            "Cryoablation",
            "Hepatocellular carcinoma",
            "Liver neoplasms",
            "Microvessel density",
            "Overall survival time",
            "Sorafenib",
            "Time to progression"
        ],
        "venue": "Academic Journal of Second Military Medical University",
        "year": 2010,
        "id": "HRySs5ty"
    },
    "pyeRtyRX": {
        "authors": [
            {
                "name": "Rui Feng Zhang",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Guo Feng Ma",
                "org": ""
            },
            {
                "name": "Fang Chun Shao",
                "org": ""
            },
            {
                "name": "Xiao Hong Wu",
                "org": ""
            },
            {
                "name": "Ke Jing Ying",
                "org": ""
            }
        ],
        "title": "Diagnostic value of transthoracic doppler echocardiography in pulmonary hypertension: A meta-analysis",
        "abstract": "Background A commonly used noninvasive method, transthoracic Doppler echocardiography (TDE) has been widely recommended for the diagnosis of pulmonary hypertension (PH). We aimed to review comprehensively the evidence for the use of TDE to diagnose PH.Methods After a systematic review of English-language studies, we used random-effects models to pool sensitivity, specificity, and other measures of accuracy of TDE for the diagnosis of PH. Summary receiver operating characteristic (SROC) curves were used to summarize overall test performance. Results Six studies met our inclusion criteria. The summary estimates for TDE in the diagnosis of PH in the included studies were as follows: sensitivity, 0.82 (95% confidence interval (CI), 0.76-0.88); specificity, 0.68 (95% CI, 0.64-0.72); positive likelihood ratio (PLR), 2.88 (95% CI, 1.77-4.70); negative likelihood ratio (NLR), 0.31 (95% CI, 0.18-0.53); and diagnostic odds ratio (DOR), 11.36 (95% CI, 4.62-27.94). Conclusions Current evidence suggests that TDE is a test with acceptable mixed sensitivity, but in isolation, it has insufficient specificity for detecting PH. It may be useful as a first-line surveillance modality in patients in whom PH is suspected. The value of the combination of TDE with other noninvasive methods for PH detection warrants further investigation. \u00a9 2010 American Journal of Hypertension, Ltd.",
        "keywords": [
            "blood pressure",
            "diagnosis",
            "hypertension",
            "meta-analysis",
            "noninvasive",
            "pulmonary hypertension",
            "transthoracic Doppler echocardiography"
        ],
        "venue": "American Journal of Hypertension",
        "year": 2010,
        "id": "pyeRtyRX"
    },
    "HSktc0y7": {
        "authors": [
            {
                "name": "Hong Zhao",
                "org": "State Key Laboratory for Diagnosis and Treatment of Infectious Diseases"
            },
            {
                "name": "Jun Fan",
                "org": "State Key Laboratory for Diagnosis and Treatment of Infectious Diseases"
            },
            {
                "name": "Jian-Hua Hu",
                "org": "State Key Laboratory for Diagnosis and Treatment of Infectious Diseases"
            },
            {
                "name": "Hai-N\u00fc Gao",
                "org": "State Key Laboratory for Diagnosis and Treatment of Infectious Diseases"
            },
            {
                "name": "Mei-Fang Yang",
                "org": "State Key Laboratory for Diagnosis and Treatment of Infectious Diseases"
            },
            {
                "name": "Xuan Zhang",
                "org": "State Key Laboratory for Diagnosis and Treatment of Infectious Diseases"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory for Diagnosis and Treatment of Infectious Diseases"
            },
            {
                "name": "Wei-Hang Ma",
                "org": "State Key Laboratory for Diagnosis and Treatment of Infectious Diseases"
            }
        ],
        "title": "The correlation of HBV infection and HCMV reactive infection after liver transplantation",
        "abstract": "Objective: To study the correlation of HBV infection pretransplantation and posttransplantation and HCMV recurrence after liver transplantation (LT). Methods: We reviewed historical patient medical records of LT patients in recent two years in our hospital. All the patients were divided into HBV infection group and a control group based on a peripheral blood HB antigen assay before LT. The HBV infection group was divided into HBV reactive infection group and HBV non-relapse group. HCMV antigen pp65 was detected by immunohistochemical methods. HB antigens and antibodies were detected by time-resolved fluorescence immunoassay, and liver enzyme levels were detected by conventional methods. Results: Comparing two groups of patients, pp65-positive rates of LT patients with HBV infection and control group patients were 84.3% and 57.9% respectively (P=0.024). While in HBV recurrence infection group and non-recurrence infection group, the incidences of HCMV recurrence were 90.9% and 83.3% (P=0.843). The changes in the liver transaminases level in both groups have no statistical significance (P>0.05). Conclusion: Pretransplantation HBV infection may increase the incidence of HCMV recurrence. Posttransplantation HBV reactive infection, however, may not increase the incidence of HCMV reactive infection. Meanwhile, compare with either HBV infection or HCMV infection alone, co-infection may not serious in liver enzymes levels.",
        "keywords": [
            "Cytomegalovirus",
            "Hepatitis B virus",
            "Liver transplantation",
            "Transaminase"
        ],
        "venue": "Chinese Journal of Microbiology and Immunology",
        "year": 2010,
        "id": "HSktc0y7"
    },
    "xhRiyjhH": {
        "authors": [
            {
                "name": "Li-Ming Wu",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Key Lab of Organ Transplantation"
            },
            {
                "name": "Zhe Yang",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Key Lab of Organ Transplantation"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Key Lab of Organ Transplantation"
            },
            {
                "name": "Feng Zhang",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Key Lab of Organ Transplantation"
            },
            {
                "name": "Hai-Yang Xie",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Key Lab of Organ Transplantation"
            },
            {
                "name": "Xiao-Wen Feng",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Key Lab of Organ Transplantation"
            },
            {
                "name": "Jian Wu",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Key Lab of Organ Transplantation"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Key Lab of Organ Transplantation"
            }
        ],
        "title": "Identification of histone deacetylase 3 as a biomarker for tumor recurrence following liver transplantation in HBV-associated hepatocellular carcinoma",
        "keywords": [
            ""
        ],
        "venue": "PLoS ONE",
        "year": 2010,
        "id": "xhRiyjhH"
    },
    "kzL1nrUC": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Wuhua Zhou",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Liming Wu",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Xiaobo Yu",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Chunyang Xing",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Shusen Zheng",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            }
        ],
        "title": "The association of frequent allelic loss on 17p13.1 with early metastastic recurrence of hepatocellular carcinoma after liver transplantation",
        "abstract": "Background and Objectives: Identification and characterization of loss of heterozygosity (LOH) can determine putative tumor suppressor genes (TSGs) and provide a variety of molecular markers for hepatocellular carcinoma (HCC). This study aimed to investigate LOH status on chromosomes 4q, 6q, 8p, 9p, and 17p, and to explore their clinical significances in HCC post-liver transplantation. Methods A total of 37 patients with HCC who underwent liver transplantation were enrolled. LOH was examined using 34 microsatellite markers located on 4q13-3q5, 6q27, 8p22-p23, 9p21-p22, and 17p12-p13. Results The frequency of LOH at each microsatellite locus ranged from 23% to 75%, with a mean value of 53.1%. Frequencies of LOH on 4q, 6q, 8p, 9p, and 17p were 62% (23 of 37), 30% (11 of 37), 49% (18 of 37), 46% (16 of 35), and 68% (25 of 37), respectively. LOHs on certain chromosomal regions were significantly associated with age, AFP level, tumor size, tumor multiplicity, histological grade, and metastatic recurrence. Conclusions LOH on 17p13.1 correlated to metastatic HCC recurrence, while LOH on 4q and 8p was found to be associated with progression of HCC. Thus, potential novel biomarkers or TSGs for prognosis and treatment of HCC may harbor on these regions. \u00a9 2010 Wiley-Liss, Inc.",
        "keywords": [
            "clinical significance",
            "microsatellite marker",
            "tumor suppressor gene (TSG)"
        ],
        "venue": "Journal of Surgical Oncology",
        "year": 2010,
        "id": "kzL1nrUC"
    },
    "WLp0izyK": {
        "authors": [
            {
                "name": "Wu Zhang",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Jian Wu",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Hai-Yang Xie",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Key Laboratory of Organ Transplantation"
            }
        ],
        "title": "Fluvastatin, a lipophilic statin, induces apoptosis in human hepatocellular carcinoma cells through mitochondria-operated pathway",
        "keywords": [
            "Fluvastatin",
            "Hepatocellular carcinoma",
            "Mitochondria-operated pathway"
        ],
        "venue": "Indian Journal of Experimental Biology",
        "year": 2010,
        "id": "WLp0izyK"
    },
    "1zgVuLdu": {
        "authors": [
            {
                "name": "Zhe Yang",
                "org": "Department of Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Surgery"
            },
            {
                "name": "Li-Ming Wu",
                "org": "Department of Surgery"
            },
            {
                "name": "Hai-Yang Xie",
                "org": "Department of Surgery"
            },
            {
                "name": "Feng Zhang",
                "org": "Department of Surgery"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Department of Surgery"
            }
        ],
        "title": "Combination of polymorphisms within the HDAC1 and HDAC3 gene predict tumor recurrence in hepatocellular carcinoma patients that have undergone transplant therapy",
        "abstract": "Background: Histone deacetylases (HDACs) have been reported to be poor prognostic indicators in patients with cancer. However, no data are available for the role of single nucleotide polymorphism (SNP) of class I HDAC in hepato-cellular carcinoma (HCC). Therefore, we investigated the association of class I HDAC isoforms genomic polymorphisms with risk of HCC and tumor recurrence following liver transplantation (LT). Methods: One hundred and ninety-six Chinese subjects consisting of 97 HCC patients and 99 controls were enrolled in this study. Nine polymorphisms of the HDAC1, HDAC2, and HDAC3 gene (rs2530223, rs1741981, rs2547547, rs13204445, rs6568819, rs10499080, rs11741808, rs2475631, rs11391) were examined using Applied Biosystems SNaP-Shot and TaqMan technology. Results: We found no significant difference in genotype frequencies between the HCC cases and controls. In terms of tumor recurrence following LT, patients carrying the T allele of HDAC1 SNP rs1741981 showed a favorable outcome for recurrence free survival when compared with patients homozygous for CC. In addition, the same significant trend was observed in HDAC3 SNP rs2547547. Kaplan-Meier analysis showed that the combination of the T variant allele (CT+TT) of HDAC1 SNP rs1741981 and the homozygous TT variant allele of HDAC3 SNP rs2547547 was the most favorable prognostic factor. The risk for postoperative tumor recurrence was about 2.2-fold lower for patients with this genotype combination compared with carriers of the HDAC1 SNP rs1741981 CC and HDAC3 SNP rs2547547 CT genotype combination (hazard ratio: 2.235, p=0.003). Conclusions: Our data suggest that combined analysis of HDAC1 SNP rs1741981 and HDAC3 SNP rs2547547 may be a potential genetic marker for HCC recurrence in LT patients. \u00a9 2010 by Walter de Gruyter Berlin New York.",
        "keywords": [
            "genetic polymorphism",
            "hepatocellular carcinoma",
            "histone deacetylase",
            "recurrence",
            "transplantation"
        ],
        "venue": "Clinical Chemistry and Laboratory Medicine",
        "year": 2010,
        "id": "1zgVuLdu"
    },
    "i6RziC9w": {
        "authors": [
            {
                "name": "Jieliang Li",
                "org": "Department of Pathology and Laboratory Medicine"
            },
            {
                "name": "Shuxian Hu",
                "org": "Neuroimmunology Laboratory"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Pathology and Laboratory Medicine"
            },
            {
                "name": "Li Ye",
                "org": "Department of Pathology and Laboratory Medicine"
            },
            {
                "name": "Xu Wang",
                "org": "Department of Pathology and Laboratory Medicine"
            },
            {
                "name": "Jie Ho",
                "org": "Department of Pathology and Laboratory Medicine"
            },
            {
                "name": "Wenzhe Ho",
                "org": "Animal Biosafety Level 3 Laboratory"
            }
        ],
        "title": "Interferon lambda inhibits herpes simplex virus type I infection of human astrocytes and neurons",
        "abstract": "Herpes simplex virus Type I (HSV-1) is a neurotropic virus that is capable of infecting not only neurons, but also microglia and astrocytes and can establish latent infection in the central nervous system (CNS). We investigated whether IFN lambda (IFN-\u03bb), a newly identified member of IFN family, has the ability to inhibit HSV-1 infection of primary human astrocytes and neurons. Both astrocytes and neurons were found to be highly susceptible to HSV-1 infection. However, upon IFN-\u03bb treatment, HSV-1 replication in both astrocytes and neurons was significantly suppressed, which was evidenced by the reduced expression of HSV-1 DNA and proteins. This IFN-\u03bb-mediated action on HSV-1 could be partially neutralized by antibody to IFN-\u03bb receptor. Investigation of the mechanisms showed that IFN-\u03bb treatment of astrocytes and neurons resulted in the upregulation of endogenous IFN-7alpha;/\u03b2 and several IFN-stimulated genes (ISGs). To block IFN-\u03b1/\u03b2 receptor by a specific antibody could compromise the IFN-\u03bb actions on HSV-1 inhibition and ISG induction. In addition, IFN-\u03bb treatment induced the expression of IFN regulatory factors (IRFs) in astrocytes and neurons. Furthermore, IFN-\u03bb treatment of astrocytes and neurons resulted in the suppression of suppressor of cytokine signaling 1 (SOCS-1), a key negative regulator of IFN pathway. These data suggest that IFN-\u03bb possesses the anti-HSV-1 function by promoting Type I IFN-mediated innate antiviral immune response in the CNS cells. \u00a9 2010 Wiley-Liss, Inc.",
        "keywords": [
            "HSV-1",
            "IFN regulatory factor",
            "IFN-\u03bb",
            "IFN-7alpha",
            "/\u03b2",
            "SOCS-1"
        ],
        "venue": "GLIA",
        "year": 2011,
        "id": "i6RziC9w"
    },
    "gHXBlmIt": {
        "authors": [
            {
                "name": "Xiao Xu",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, Zhejiang University School of Medicine"
            },
            {
                "name": "Xuyong Wei",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, Zhejiang University School of Medicine"
            },
            {
                "name": "Qi Ling",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, Zhejiang University School of Medicine"
            },
            {
                "name": "Jun Cheng",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, Zhejiang University School of Medicine"
            },
            {
                "name": "Bin Zhou",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, Zhejiang University School of Medicine"
            },
            {
                "name": "Haiyang Xie",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, Zhejiang University School of Medicine"
            },
            {
                "name": "Lin Zhou",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, Zhejiang University School of Medicine"
            },
            {
                "name": "Shusen Zheng",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, Zhejiang University School of Medicine"
            }
        ],
        "title": "Identification of two portal vein tumor thrombosis associated proteins in hepatocellular carcinoma: Protein disulfide-isomerase A6 and apolipoprotein A-I",
        "abstract": "Background and Aim: Portal vein tumor thrombus (PVTT) is one of the factors that can affect prognosis and survival of hepatocellular carcinoma (HCC). In the present study, we aimed to find out some biomarkers associated with vascular invasion features of HCC with the method of comparative proteomic analysis. Methods: The proteins were extracted from a pair of HCC tissues with PVTT and without PVTT, and then separated by two-dimensional polyacrylamide gel electrophoresis. Differentially expressed protein spots were identified by matrix assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS). Further analysis of two proteins were completed using real-time fluorescence quantitative polymerase chain reaction and western-blot in 40 HCC tissues with PVTT (n=20) and without PVTT (n=20). Results: Among 465 protein spots displayed on the gels, 33 unique proteins (>twofold change, P<0.01) were identified, including 24 upregulated in HCC tissue without PVTT and nine upregulated in HCC tissue with PVTT. The real-time fluorescence quantitative PCR showed no statistically significant difference between HCC tissues with PVTT and without PVTT for mRNA expressions of protein disulfide-isomerase, A6 (PDI A6) (P=0.137) and apolipoprotein A-I (Apo A-I) (P=0.718). However, compared with HCC tissues without PVTT, protein expression of PDI A6 was higher in HCC tissues with PVTT (P<0.001), while protein expression of Apo A-I was lower in HCC tissues with PVTT (P=0.012). Conclusions: PDI A6 and Apo A-I are closely related to vascular invasion feature of HCC. \u00a9 2011 Journal of Gastroenterology and Hepatology Foundation and Blackwell Publishing Asia Pty Ltd.",
        "keywords": [
            "Apolipoprotein A-I",
            "Hepatocellular carcinoma",
            "Portal vein tumor thrombosis",
            "Protein disulfide-isomerase A6",
            "Proteomics"
        ],
        "venue": "Journal of Gastroenterology and Hepatology (Australia)",
        "year": 2011,
        "id": "gHXBlmIt"
    },
    "H9XMb34i": {
        "authors": [
            {
                "name": "Liang Fang",
                "org": ""
            },
            {
                "name": "Huimng Wang",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Da Yu",
                "org": ""
            }
        ],
        "title": "Akt-FOXO3a signaling axis dysregulation in human oral squamous cell carcinoma and potent efficacy of FOXO3a-targeted gene therapy",
        "abstract": "Phosphoinositide-3-kinase (PI3K)/Akt pathway has been shown to be activated in oral squamous cell carcinoma (OSCC). Activation of Akt suppresses FOXO transcription factor-mediated growth arrest and apoptosis in various cancers. We investigated FOXO3a and phosphor(p)-Akt expression and potential efficacy of FOXO3a-targeted gene therapy in OSCC. Low expression of FOXO3a was negatively associated with overexpression of p-Akt and histological grade using immunohistochemistry. Akt-FOXO3a axis was also examined by detection of FOXO3a expression after induction or inhibition of Akt activity in Tca8113 OSCC cells. Transfection of a constitutively active form of FOXO3a (FOXO3a\n                        ",
        "keywords": [
            "Akt",
            "Apoptosis",
            "Cell cycle",
            "FOXO3a",
            "Gene therapy",
            "Oral squamous cell carcinoma (OSCC)"
        ],
        "venue": "Oral Oncology",
        "year": 2011,
        "id": "H9XMb34i"
    },
    "FbMsDpL2": {
        "authors": [
            {
                "name": "Tian-Qi Liu",
                "org": "Department of Hepatobiliary Surgery"
            },
            {
                "name": "Jun Fan",
                "org": "State Key Laboratory for Diagnosis and Treatment of Infectious Disease"
            },
            {
                "name": "Lin Zhou",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            }
        ],
        "title": "Effects of suppressing glucose transporter-1 by an antisense oligodeoxynucleotide on the growth of human hepatocellular carcinoma cells",
        "abstract": "BACKGROUND: The glucose transporter-1 (Glut-1), a key rate-limiting factor in the transport and metabolism of glucose in cancer cells, is over-expressed in many human cancer cells and this over-expression is correlated with poor biological behavior. The increased levels of Glut-1 expression in hepatocellular carcinoma (HCC) cells functionally affect tumorigenicity. This study was undertaken to investigate effects of suppressing Glut-1 by an antisense oligodeoxynucleotide (AS-ODN) on the growth of human hepatocellular carcinoma (HepG-2) cells. METHODS: We used AS-ODN targeting against the Glut-1 gene in a HepG-2 cell line. There were four experimental groups: empty pcDNA3.1 vector (mock transfection), pcDNA3.1-anti-Glut (+), pcDNA3.1-Glut (+), and non-transfected HepG-2 cells. The Glut-1 mRNA expression was detected by RT-PCR and the Glut-1 protein expression by Western blotting after cell culture, and the glucose uptake was detected after glucose stimulation in each group. RESULTS: Compared with non-transfected HepG-2 or Glut-1 pcDNA3.1, a down-regulation of Glut-1 mRNA in HepG-2 cells transfected with anti-Glut-1 pcDNA3.1 was noted (P<0.05). Glut-1 protein in HepG-2 cells transfected with Glut-1 AS-ODN was decreased compared with nontransfected HepG-2, Glut-1 pcDNA3.1, or empty vectors. Glucose uptake by the HepG-2 cells transfected with AS-ODN was decreased at 1 hour after glucose stimulation. CONCLUSIONS: The application of Glut-1 AS-ODN can downregulate the expression of Glut-1 at mRNA and protein, and inhibit glucose uptake partially in HepG-2 cells. The Glut-1 gene maybe a potential therapeutic target for HCC. \u00a9 2011, Hepatobiliary Pancreat Dis Int. All rights reserved.",
        "keywords": [
            "Glucose transporter-1",
            "Hepatocellular carcinoma",
            "HepG-2 cell",
            "Therapeutic target"
        ],
        "venue": "Hepatobiliary and Pancreatic Diseases International",
        "year": 2011,
        "id": "FbMsDpL2"
    },
    "nhFBFbtP": {
        "authors": [
            {
                "name": "Yu-Ling Sun",
                "org": ""
            },
            {
                "name": "Sheng-Yong Yin",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Hai-Yang Xie",
                "org": ""
            },
            {
                "name": "Feng Zhang",
                "org": ""
            },
            {
                "name": "Li-Ming Wu",
                "org": ""
            },
            {
                "name": "Shu-Sen Zheng",
                "org": ""
            }
        ],
        "title": "Hepatocyte differentiation of human fibroblasts from cirrhotic liver in vitro and in vivo",
        "abstract": "BACKGROUND: Mesenchymal stem cells (MSCs) and fibroblasts have intimate relationships, and the phenotypic homology between fibroblasts and MSCs has been recently described. The aim of this study was to investigate the hepatic differentiating potential of human fibroblasts in cirrhotic liver. METHODS: The phenotypes of fibroblasts in cirrhotic liver were labeled by biological methods. After that, the differentiation potential of these fibroblasts in vitro was characterized in terms of liver-specific gene and protein expression. Finally, an animal model of hepatocyte regeneration in severe combined immunodeficient (SCID) mice was created by retrorsine injection and partial hepatectomy, and the expression of human hepatocyte proteins in SCID mouse livers was checked by immunohistochemical analysis after fibroblast administration. RESULTS: Surface immunophenotyping revealed that a minority of fibroblasts expressed markers of MSCs and hepatic epithelial cytokeratins as well as alpha-smooth muscle actin, but homogeneously expressed vimentin, desmin, prolyl 4-hydroxylase and fibronectin. These fibroblasts presented the characteristics of hepatocytes in vitro and differentiated directly into functional hepatocytes in the liver of hepatectomized SCID mice. CONCLUSIONS: This study demonstrated that fibroblasts in cirrhotic liver have the potential to differentiate into hepatocyte-like cells in vitro and in vivo. Our findings infer that hepatic differentiation of fibroblasts may serve as a new target for reversion of liver fibrosis and a cell source for tissue engineering. \u00a9 2011, Hepatobiliary Pancreat Dis Int. All rights reserved.",
        "keywords": [
            "Fibroblasts",
            "Hepatocytes",
            "Mesenchymal-epithelial transition"
        ],
        "venue": "Hepatobiliary and Pancreatic Diseases International",
        "year": 2011,
        "id": "nhFBFbtP"
    },
    "ueNdvJQX": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Xiao Hua Liu",
                "org": ""
            },
            {
                "name": "Hai Xin Bai",
                "org": ""
            },
            {
                "name": "Hong Juan Wang",
                "org": ""
            }
        ],
        "title": "A simple method for determining water content in organic solvents based on cobalt(II) complexes",
        "abstract": "A method to determine water content in organic solvents was developed based on the color change of cobalt(II) nitrate in different solvents. The color-change mechanism and optimal conditions for determining the water content were investigated. The results showed that there was a good linear relationships between the absorbance of cobalt(II) complexes in organic solvents and water contents with \u03b3 in 0.9989\u223c0.9994. This method has the advantages of low cost, good reproducibility, good sensitivity, simple in operation, fast in detection, friendly to the environment and no limitation on linear range for determining water content. It was used to determine water in samples with a satisfactory recovery in 97.81%\u223c101.24%. \u00a9 2010 Hai Xin Bai. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.",
        "keywords": [
            "Cobalt(II) nitrate",
            "Determination",
            "Organic solvent",
            "Water content"
        ],
        "venue": "Chinese Chemical Letters",
        "year": 2011,
        "id": "ueNdvJQX"
    },
    "BOscTjkR": {
        "authors": [
            {
                "name": "Liang Fang",
                "org": "Department of Oral and Maxillofacial Surgery"
            },
            {
                "name": "Huiming Wang",
                "org": "Department of Oral and Maxillofacial Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Da Yu",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation"
            }
        ],
        "title": "FOXO3a reactivation mediates the synergistic cytotoxic effects of rapamycin and cisplatin in oral squamous cell carcinoma cells",
        "abstract": "FOXO3a, a well-known transcriptional regulator, controls a wide spectrum of biological processes. The Phosphoinositide-3-kinase (PI3K)/Akt signaling pathway inactivates FOXO3a via phosphorylation-induced nuclear exclusion and degradation. A loss or gain of FOXO3a activity has been correlated with efficiency of chemotherapies in various cancers including oral squamous cell carcinoma (OSCC). Therefore, in the current study, we have investigated the FOXO3a activity modulating and antitumor effects of rapamycin and cisplatin in OSCC cells. Cisplatin inhibited proliferation and induced apoptosis in a dose-dependent way in OSCC Tca8113 cells. Rapamycin alone had no effect on cell proliferation and apoptosis. Rapamycin downregulated the expression of S-phase kinase associated protein-2 (Skp2) and increased the FOXO3a protein stability but induced the upregulation of feedback Akt activation-mediated FOXO3a phosphorylation. Cisplatin decreased the phosphorylation of FOXO3a via Akt inhibition. Rapamycin combined with cisplatin as its feedback Akt activation inhibitor revealed the most dramatic FOXO3a nuclear localization and reactivation with the prevention of its feedback loop and exposed significant synergistic effects of decreased cell proliferation and increased apoptosis in vitro and decreased tumor size in vivo. Furthermore, the downstream effects of FOXO3a reactivation were found to be accumulation of p27 and Bim. In conclusion, rapamycin/cisplatin combination therapy boosts synergistic antitumor effects through the significant FOXO3a reactivation in OSCC cells. These results may represent a novel mechanism by which rapamycin/cisplatin combination therapy proves to be a potent molecular-targeted strategy for OSCC. \u00a9 2010 Elsevier Inc.",
        "keywords": [
            "Akt",
            "Cisplatin",
            "FOXO3a",
            "Oral squamous cell carcinoma (OSCC)",
            "Rapamycin"
        ],
        "venue": "Toxicology and Applied Pharmacology",
        "year": 2011,
        "id": "BOscTjkR"
    },
    "fBz9Ikr8": {
        "authors": [
            {
                "name": "Jian Wu",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "SunYi Ye",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "XiaoFeng Xu",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Haiyang Xie",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "ShuSen Zheng",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            }
        ],
        "title": "Recipient outcomes after ABO-incompatible liver transplantation: A systematic review and meta-analysis",
        "keywords": [
            ""
        ],
        "venue": "PLoS ONE",
        "year": 2011,
        "id": "fBz9Ikr8"
    },
    "qjOrRePK": {
        "authors": [
            {
                "name": "Junfang Deng",
                "org": ""
            },
            {
                "name": "Yigang Qian",
                "org": ""
            },
            {
                "name": "Lei Geng",
                "org": ""
            },
            {
                "name": "Haiyang Xie",
                "org": ""
            },
            {
                "name": "Yan Wang",
                "org": ""
            },
            {
                "name": "Guoping Jiang",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Ming Zhang",
                "org": ""
            },
            {
                "name": "Shusen Zheng",
                "org": ""
            }
        ],
        "title": "Involvement of ERK and JNK pathways in IFN-\u03b3-induced B7-DC expression on tumor cells",
        "abstract": "Purpose: B7-DC on tumor cells was demonstrated to promote tumor immunity; however, the precise mechanism responsible for the aberrant B7-DC expression remains unknown. Interferon gamma (IFN-\u03b3) can induce B7-DC expression on macrophages and has been shown to regulate anti-tumor immunity by various mechanisms. This study was designed to investigate the relationship of IFN-\u03b3 and B7-DC on tumor cells and further explored the signal transduction pathways involved. Methods: RT-PCR and flow cytometry were used for the analysis of B7-DC expression on various tumor cells. The phosphorylation of p38, ERK1/2, JNK, Akt, and JAK2 was determined by Western blot. Results: IFN-\u03b3 markedly up-regulated B7-DC expression on various tumor cells and resulted in the phosphorylation of JAK2, JNK, ERK, p38, and Akt. Inhibition of ERK or JNK pathway significantly decreased IFN-\u03b3-induced B7-DC expression, whereas inhibition of phosphorylation of Akt, p38, and JAK2 had very little effect on IFN-\u03b3-induced B7-DC expression. Conclusions: Our findings demonstrate that the pretreatment of tumor cells with IFN-\u03b3 enhances B7-DC expression through ERK and JNK pathways. \u00a9 2010 Springer-Verlag.",
        "keywords": [
            "Akt",
            "B7-DC",
            "ERK",
            "Interferon gamma",
            "JAK2",
            "JNK",
            "p38",
            "Tumor cells"
        ],
        "venue": "Journal of Cancer Research and Clinical Oncology",
        "year": 2011,
        "id": "qjOrRePK"
    },
    "wIoAJS8h": {
        "authors": [
            {
                "name": "Xiao Hua Liu",
                "org": "College of Science"
            },
            {
                "name": "Hai Xin Bai",
                "org": "College of Science"
            },
            {
                "name": "Lin Zhou",
                "org": "College of Plant Protection"
            }
        ],
        "title": "Studies on the catalyzing transesterification of soybean oil with methanol for biodiesel using a novel porous CaO microsphere catalyst",
        "abstract": "A novel porous CaO microsphere catalyst was synthesized by calcining spherical CaCO",
        "keywords": [
            "Biodiesel",
            "Catalysis",
            "Porous CaO microsphere",
            "Transesterification"
        ],
        "venue": "Advanced Materials Research",
        "year": 2011,
        "id": "wIoAJS8h"
    },
    "cvycXe3Q": {
        "authors": [
            {
                "name": "Jennifer Meintjes",
                "org": "Centre for Orthopaedic Research"
            },
            {
                "name": "Sheng Yan",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Shusen Zheng",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Minghao Zheng",
                "org": "Centre for Orthopaedic Research"
            }
        ],
        "title": "Synthetic, biological and composite scaffolds for abdominal wall reconstruction",
        "abstract": "The reconstruction of abdominal wall defects remains a huge surgical challenge. Tension-free repair is proven to be superior to suture repair in abdominal wall reconstruction. Scaffolds are essential for tension-free repair. They are used to bridge a defect or reinforce the abdominal wall. A huge variety of scaffolds are now commercially available. Most of the synthetic scaffolds are composed of polypropylene. They provide strong tissue reinforcement, but cause a foreign body reaction, which can result in serious complications. Absorbable synthetic scaffolds, such as Dexon\u2122 (polyglycolic acid) and Vicryl\u2122 (polyglactin 910), are not suitable for abdominal wall reconstruction as they usually require subsequent surgeries to repair recurrent hernias. Composite scaffolds combine the strength of nonabsorbable synthetic scaffolds with the antiadhesive properties of the absorbable scaffold, but require long-term follow-up. Biological scaffolds, such as Permacol\u2122, Surgisis",
        "keywords": [
            "abdominal wall reconstruction",
            "biocompatibility",
            "hernia repair",
            "inflammation",
            "mesh"
        ],
        "venue": "Expert Review of Medical Devices",
        "year": 2011,
        "id": "cvycXe3Q"
    },
    "z6P71oI5": {
        "authors": [
            {
                "name": "Qi Ling",
                "org": "Department of Surgery"
            },
            {
                "name": "Xiao Xu",
                "org": "Department of Surgery"
            },
            {
                "name": "Qiang Wei",
                "org": "Department of Surgery"
            },
            {
                "name": "Xuyong Wei",
                "org": "Department of Surgery"
            },
            {
                "name": "Zhuoyi Wang",
                "org": "Department of Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Surgery"
            },
            {
                "name": "Shusen Zheng",
                "org": "Department of Surgery"
            }
        ],
        "title": "Impact of preexisting diabetes mellitus on outcome after liver transplantation in patients with hepatitis B virus-related liver disease",
        "abstract": "Background: Preexisting diabetes mellitus (DM) has been reported to have an adverse consequence on patient prognosis after liver transplantation in the West. So far, there are few reports on the effect of preexisting DM on outcome of liver transplant recipients with HBV infection. Aims: We aimed to examine the impact of preexisting DM on post-transplant outcome in Chinese patients with HBV-related liver disease. Methods: The post-transplant morbidities and patient survival were compared between 48 diabetes patients (DM group) and 96 non-diabetes patients (control group) matched for age, gender, primary disease and model for end-stage liver diseases score. The DM group was further divided into hyperglycemia patients (fasting blood glucose >8.0 mmol/L, n = 22) and non-hyperglycemia patients (fasting blood glucose \u22648.0 mmol/L, n = 26). Results: Patient characteristics were comparable between both groups, except a higher incidence of hepatic encephalopathy in the DM group than that in the control group (22.9% vs. 10.4%, P = 0.045). The incidences of post-transplant complications and patient survival did not differ significantly between the DM and control groups, or between non-hyperglycemia patients and their matched case controls. Hyperglycemia patients showed a higher incidence of post-transplant sepsis (18.2% vs. 2.3%, P = 0.039) and biliary complications (31.8% vs. 6.8%, P = 0.012) than their matched case controls. Conclusions: Preexisting DM is not a contraindication for liver transplantation in patients with HBV-related liver disease. A tight control of blood glucose to a level of \u22648.0 mmol/L was necessary to reduce the risk of complications after liver transplantation. \u00a9 2010 Springer Science+Business Media, LLC.",
        "keywords": [
            "Diabetes mellitus",
            "Hepatitis B virus",
            "Liver transplantation",
            "Postoperative complications",
            "Prognosis"
        ],
        "venue": "Digestive Diseases and Sciences",
        "year": 2011,
        "id": "z6P71oI5"
    },
    "Ec036ebd": {
        "authors": [
            {
                "name": "Shuang Zhu",
                "org": "School of Life Science and Biopharmacology"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Life Science and Biopharmacology"
            },
            {
                "name": "Huimin Pang",
                "org": "School of Life Science and Biopharmacology"
            },
            {
                "name": "Hongliang Huang",
                "org": "School of Life Science and Biopharmacology"
            },
            {
                "name": "Xiaoxia Gao",
                "org": "School of Pharmacy"
            },
            {
                "name": "Changqing Zeng",
                "org": "School of Traditional Chinese Medicine"
            }
        ],
        "title": "Molecular identification of one Uncaria plant",
        "abstract": "Objective: In order to identify a species of Uncaria , molecular phylogenetic analysis was carried out by using the rDNA ITS sequence as molecular marker. Method: Total DNA was extracted from the plant with modified CTAB method and thereby rDNA ITS regions were amplified with universally conserved primer. The rDNA ITS amplicon was characterized by cloning, sequencing, blasting in GenBank and phylogenetic analyses using PAUP by maximum parsimony (MP) criteria. Result: The rDNA ITS entire sequence of this species of Uncaria was 719 bp. The sequence is related to the U. sinensis available in GenBank and the similarity reaches 99.7%. Conclusion: Based on molecular biology methods of rDNA ITS region analysis, molecular identification is available in accurate classification on this species of Uncaria.",
        "keywords": [
            "ITS sequence",
            "Molecular identification",
            "Uncaria"
        ],
        "venue": "Zhongguo Zhongyao Zazhi",
        "year": 2011,
        "id": "Ec036ebd"
    },
    "83lTThX8": {
        "authors": [
            {
                "name": "Lin Chen",
                "org": "Zhejiang University School of Medicine"
            },
            {
                "name": "Xiao-Jun Xie",
                "org": "Zhejiang University School of Medicine"
            },
            {
                "name": "Yu-Fu Ye",
                "org": "Zhejiang University School of Medicine"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Hai-Yang Xie",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Qin-Fen Xie",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Jiong Tian",
                "org": "Department of Nephrology"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            }
        ],
        "title": "Kupffer cells contribute to concanavalin A-induced hepatic injury through a Th1 but not Th17 type response-dependent pathway in mice",
        "abstract": "BACKGROUND: Increasing evidence suggests that a close interaction of Kupffer cells with T cells plays a central role in concanavalin A-induced hepatic injury in mice, but the underlying mechanisms remain obscure. The present study aimed to determine the relative roles of Th1 and Th17 type responses in concanavalin A-induced hepatic injury in mice, and to investigate whether or not Kupffer cells contribute to hepatic injury via a Th1 or Th17 type response-dependent pathway. METHODS: Immune-mediated hepatic injury was induced in C57BL/6 mice by intravenous injection of concanavalin A. Kupffer cells were inactivated by pretreatment with gadolinium chloride 24 hours before the concanavalin A injection. The interferon-gamma (IFN-\u03b3) and interleukin-17 (IL-17) pathways were blocked by specific neutralizing antibodies. Hepatic injury was assessed using serum transferase activity and pathological analysis. Expression of inflammatory cytokines within the liver was detected by real-time polymerase chain reaction and immunohistochemistry. RESULTS: Neutralization of IFN-\u03b3 significantly attenuated concanavalin A-induced hepatic injury. However, neutralization of IL-17 failed to suppress the injury. Inactivation of Kupffer cells by gadolinium chloride pretreatment protected against concanavalin A-induced injury and significantly reduced hepatic cytokine levels including TNF-a, IL-6 and IFN-\u03b3 but not IL-17. CONCLUSION: Our findings suggest that Kupffer cells contribute to concanavalin A-induced hepatic injury via a Th1 type response-dependent pathway and production of inflammatory cytokines including TNF-a, IL-6 and IFN-\u03b3. \u00a9 2011, Hepatobiliary Pancreat Dis Int.",
        "keywords": [
            "Concanavalin A",
            "Hepatic injury",
            "Hepatitis",
            "Interferon-gamma",
            "Interleukin-17",
            "Kupffer cells"
        ],
        "venue": "Hepatobiliary and Pancreatic Diseases International",
        "year": 2011,
        "id": "83lTThX8"
    },
    "16ZOmoIR": {
        "authors": [
            {
                "name": "Yan Dong",
                "org": ""
            },
            {
                "name": "Yimin Zhao",
                "org": ""
            },
            {
                "name": "Shizhu Bai",
                "org": ""
            },
            {
                "name": "Guofeng Wu",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Bo Wang",
                "org": ""
            }
        ],
        "title": "Three-dimensional anthropometric analysis of chinese faces and its application in evaluating facial deformity",
        "abstract": "Purpose: The aims of this study are to introduce a novel method of 3-dimensional (3D) analysis of the face and to provide normative data of the Chinese face for surgeons. Materials and Methods: Fifty men and 50 women were recruited, and a 3D stereophotogrammetry system was used to acquire their facial image data. For each subject, the image was aligned to a unified coordinate system, and coordinate values of 31 facial landmarks were collected. Mean values for each landmark were calculated within genders, and 3D models of both genders were constructed based on the mean values. Subsequently, to evaluate the sexual dimorphism, the models were superimposed. Then, to delineate the shape differences independent of size, the models were normalized and superimposed again. The application of the 3D models was also exemplified by analysis of a subject's facial deformity. Results: Linear and polyhedron 3D models representing the facial shape were built for both genders. The superimposed models and the absolute differences between each landmark in both genders illustrated the sexual dimorphism of the Chinese face, and the normalized models and relative difference for each landmark also delineated the shape differences independent of size. In addition, a subject's facial deformity was evaluated by referring to the normative 3D facial models. Conclusions: This study describes a new 3D analysis method for facial morphology. Three-dimensional models representing the facial shape of Chinese subjects were built, and sexual dimorphism was investigated. These would provide useful guidance for facial anthropometry and plastic surgeons in clinical practice. \u00a9 2011 American Association of Oral and Maxillofacial Surgeons.",
        "keywords": [
            ""
        ],
        "venue": "Journal of Oral and Maxillofacial Surgery",
        "year": 2011,
        "id": "16ZOmoIR"
    },
    "DBBxXvIb": {
        "authors": [
            {
                "name": "Wu Zhang",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Song-Ming Ding",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Hai-Yang Xie",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Xiao Xu",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Jian Wu",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Qi-Xin Chen",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Feng Zhang",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Ba-Jing Wei",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Ahmed Taki Eldin",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            }
        ],
        "title": "Aberrant methylation of the CADM1 promoter is associated with poor prognosis in hepatocellular carcinoma treated with liver transplantation",
        "keywords": [
            "Cell adhesion molecule 1",
            "DNA methylation",
            "Hepatocellular carcinoma",
            "Liver transplantation",
            "Prognosis"
        ],
        "venue": "Oncology Reports",
        "year": 2011,
        "id": "DBBxXvIb"
    },
    "nAc4kYVt": {
        "authors": [
            {
                "name": "Zhe Yang",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Li-Ming Wu",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Ming-Chun Lai",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Hai-Yang Xie",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Feng Zhang",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            }
        ],
        "title": "Overexpression of long non-coding RNA HOTAIR predicts tumor recurrence in hepatocellular carcinoma patients following liver transplantation",
        "abstract": "Background: The long noncoding RNA HOTAIR has been reported as a poor prognostic biomarker in patients with breast cancer. The aim of the present study is to examine the expression pattern of HOTAIR in hepatocellular carcinoma (HCC) and its clinical significance as well as its biological role in tumor progression. Materials and Methods: We examined the expression of HOTAIR in 110 HCC samples using real-time reverse transcription-polymerase chain reaction and analyzed its correlation with clinical parameters and prognosis in 60 HCC patients that have undergone liver transplantation (LT). Suppression of HOTAIR using siRNA was performed to explore its roles in tumor progression. Results: The expression level of HOTAIR in cancer tissues was higher than in adjacent noncancerous tissues. High expression level of HOTAIR was an independent prognostic factor for predicting HCC recurrence in LT patients (P = .001, hazard ratio, 3.564). Furthermore, in patients exceeding the Milan criteria, those with a high expression level of HOTAIR revealed a significantly shorter recurrence-free survival. Moreover, siRNA suppression of HOTAIR in a liver cancer cell line reduced cell viability and cell invasion, sensitized TNF-\u03b1 induced apoptosis, and increased the chemotherapeutic sensitivity of cancer cells to cisplatin and doxorubicin. Conclusions: The high expression level of HOTAIR in HCC could be a candidate biomarker for predicting tumor recurrence in HCC patients who have undergone liver transplant therapy and might be a potential therapeutic target. \u00a9 2011 Society of Surgical Oncology.",
        "keywords": [
            ""
        ],
        "venue": "Annals of Surgical Oncology",
        "year": 2011,
        "id": "nAc4kYVt"
    },
    "IjBRTz1T": {
        "authors": [
            {
                "name": "Wei Deng",
                "org": "Key Laboratory of Ministry of Education for Bio-resources and Eco-environment"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Ministry of Education for Bio-resources and Eco-environment"
            },
            {
                "name": "Yuntao Zhou",
                "org": "Key Laboratory of Ministry of Education for Bio-resources and Eco-environment"
            },
            {
                "name": "Yujia Wang",
                "org": "Key Laboratory of Ministry of Education for Bio-resources and Eco-environment"
            },
            {
                "name": "Maolin Wang",
                "org": "Key Laboratory of Ministry of Education for Bio-resources and Eco-environment"
            },
            {
                "name": "Yun Zhao",
                "org": "Key Laboratory of Ministry of Education for Bio-resources and Eco-environment"
            }
        ],
        "title": "Isolation and characterization of three duplicated PISTILLATA genes in Brassica napus",
        "abstract": "Three coding region cDNAs of duplicated PISTILLATA-like (PI-like) MADS-box genes, BnPI-1, BnPI-2 and BnPI-3, were isolated from B. napus by RT-PCR. The sequence analysis showed that the three PI cDNAs possessed 627, 627 and 625 nucleotides, respectively, and their nucleotide sequences had 96.49-98.72% similarity. Due to a deletion of two nucleotides, the protein sequence in the downstream of the frameshift site was altered in BnPI-3. Therefore, there were only 171 amino acids coded by BnPI-3, while there were 208 ones coded by BnPI-1 or BnPI-2. The deduced amino acid identity between BnPI-1 and BnPI-2 was 97.6% and the amino acid sequence of BnPI-1 and BnPI-2 shared 72.6% identity with BnPI-3. The deduced amino acid sequences of the coded proteins indicated high homology with the members of the PI family of MADS-box proteins. RT-PCR analysis showed that BnPI transcription was only detectable in petals and stamens. The yeast two-hybrid assays results showed that the three BnPI proteins exhibited different dimerization affinities with three BnAP3. BnPI-1 and BnPI-2 could form strong heterodimers with BnAP3. The dimerization affinity of BnPI-1 with BnAP3-4 is the strongest in all the combinations, while the affinity of BnPI-3 with BnAP3-4 is the weakest. The dimerization affinity to BnAP3-4 of BnPI-1 is 3.5 times of that of BnPI-3. The distinguished weak interaction to AP3 of BnPI-3 is probably due to the loss of the PI motif. The divergences of sequence and affinity of protein interaction might reflect some functional divergence of the three PI genes in B. napus. \u00a9 Springer Science+Business Media B.V. 2010.",
        "keywords": [
            "Brassica napus",
            "Gene duplication",
            "MIKC",
            "PISTILLATA",
            "Yeast two-hybrid assays"
        ],
        "venue": "Molecular Biology Reports",
        "year": 2011,
        "id": "IjBRTz1T"
    },
    "73N9zjkh": {
        "authors": [
            {
                "name": "Hai-Yang Xie",
                "org": ""
            },
            {
                "name": "Jun Cheng",
                "org": ""
            },
            {
                "name": "Chun-Yang Xing",
                "org": ""
            },
            {
                "name": "Jin-Jin Wang",
                "org": ""
            },
            {
                "name": "Rong Su",
                "org": ""
            },
            {
                "name": "Xu-Yong Wei",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Shu-Sen Zheng",
                "org": ""
            }
        ],
        "title": "Evaluation of hepatitis B viral replication and proteomic analysis of HepG2.2.15 cell line after knockdown of HBx",
        "abstract": "BACKGROUND: Hepatitis B virus (HBV) is one of the major pathogens of human liver disease. Studies have shown that HBV X protein (HBx) plays an important role in promoting viral gene expression and replication. In this study we performed a global proteomic profling to identify the downstream functional proteins of HBx, thereby detecting the mechanisms of action of HBx on virion replication. METHODS: HBx in the HepG2.2.15 cell line was knocked down by the transfection of small interfering RNA (siRNA) The replication level of HBV was evaluated by microparticle enzyme immunoassay analysis of HBsAg and HBeAg in the culture supernatant, and real-time quantitative PCR analysis of HBV DNA. Two-dimensional electrophoresis combined with MALDI-TOF/TOF was performed to analyze the changes in protein expression profle after treatment with HBx siRNA. RESULTS: Knockdown of HBx disturbed HBV replication in vitro. HBx target siRNA signifcantly inhibited the expression of HBsAg, HBeAg and the replication of HBV DNA. Twelve signifcantly changed proteins (7 upregulated and 5 downregulated) were successfully identifed by MALDI TOF/TOF using proteomics differential expression analysis after the knockdown of HBx. Among these identifed proteins HSP70 was validated by Western blotting. CONCLUSION: The results of the study indicated the positive effect of HBx on HBV replication, and a group of downstream target proteins of HBx may be responsible for this effect. \u00a9 2011, Hepatobiliary Pancreat Dis Int. All rights reserved.",
        "keywords": [
            "Hbx",
            "Hepatitis b virus",
            "Proteomics",
            "Replication"
        ],
        "venue": "Hepatobiliary and Pancreatic Diseases International",
        "year": 2011,
        "id": "73N9zjkh"
    },
    "G8agLAel": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Division of Histology and Embryology"
            },
            {
                "name": "Jieliang Li",
                "org": "Department of Pathology and Laboratory Medicine"
            },
            {
                "name": "Xu Wang",
                "org": "Department of Pathology and Laboratory Medicine"
            },
            {
                "name": "Li Ye",
                "org": "Department of Pathology and Laboratory Medicine"
            },
            {
                "name": "Wei Hou",
                "org": "Department of Pathology and Laboratory Medicine"
            },
            {
                "name": "Jie Ho",
                "org": "Department of Pathology and Laboratory Medicine"
            },
            {
                "name": "He Li",
                "org": "Division of Histology and Embryology"
            },
            {
                "name": "Wenzhe Ho",
                "org": "Department of Pathology and Laboratory Medicine"
            }
        ],
        "title": "IL-29/IL-28A suppress HSV-1 infection of human NT2-N neurons",
        "abstract": "The newly identified cytokines, IL-28/IL-29 (also termed type III IFNs), are able to inhibit a number of viruses. Here, we examined the antiviral effects of IL-29/IL-28A against herpes simplex virus type 1 (HSV-1) in human NT2-N neurons and CHP212 neuronal cells. Both IL-29 and IL-28A could efficiently inhibit HSV-1 replication in neuronal cells, as evidenced by the reduced expression of HSV-1 DNA and proteins. This inhibitory effect of IL-29 and IL-28A against HSV-1 could be partially blocked by antibody to IL-10R\u03b2, one of the key receptors for IL-29 and IL-28A. To explore the underlying antiviral mechanisms employed by IL-29/IL-28A, we showed that IL-29/IL-28A could selectively induce the expression of several Toll-like receptors (TLRs) as well as activate TLR-mediated antiviral pathway, including IFN regulatory factor 7, IFN-\u03b1, and the key IFN-\u03b1 stimulated antiviral genes. \u00a9 Journal of NeuroVirology, Inc. 2011.",
        "keywords": [
            "HSV-1",
            "IFN",
            "IRF-7",
            "Neuron",
            "TLR"
        ],
        "venue": "Journal of NeuroVirology",
        "year": 2011,
        "id": "G8agLAel"
    },
    "xgmqgxKi": {
        "authors": [
            {
                "name": "Hefei Huang",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Yu Han",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Xiaoyan Wang",
                "org": "Center for Molecular Physiology Research"
            },
            {
                "name": "Caiyu Chen",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Changqing Yu",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Duofen He",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Hongyong Wang",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Lin Zhou",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Laureano D. Asico",
                "org": "Center for Molecular Physiology Research"
            },
            {
                "name": "Pedro A. Jose",
                "org": "Center for Molecular Physiology Research"
            },
            {
                "name": "Chunyu Zeng",
                "org": "Chongqing Institute of Cardiology"
            }
        ],
        "title": "Inhibitory effect of the D3 dopamine receptor on insulin receptor expression and function in vascular smooth muscle cells",
        "abstract": "Background Vascular smooth muscle cell (VSMC) proliferation is regulated by numerous hormones and humoral factors. Our previous study found that stimulation of D",
        "keywords": [
            "blood pressure",
            "dopamine receptor",
            "hypertension",
            "insulin receptor",
            "proliferation",
            "vascular smooth muscle cells"
        ],
        "venue": "American Journal of Hypertension",
        "year": 2011,
        "id": "xgmqgxKi"
    },
    "sOu8JShZ": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Lili Lin",
                "org": ""
            },
            {
                "name": "Jie Ji",
                "org": ""
            },
            {
                "name": "Mingsheng Xie",
                "org": ""
            },
            {
                "name": "Xiaohua Liu",
                "org": ""
            },
            {
                "name": "Xiaoming Feng",
                "org": ""
            }
        ],
        "title": "Catalytic asymmetric vinylogous Mannich-type (AVM) reaction of nonactivated \u03b1-angelica lactone",
        "abstract": "A direct highly diastereo- and enantioselective asymmetric vinylogous Mannich-type (AVM) reaction of aldimines with nonactivated natural \u03b1-angelica lactone has been successfully developed. It was demonstrated that the nonactivated natural \u03b1-angelica lactone is a useful vinylogous nucleophile to give the chiral \u03b4-amino \u03b3,\u03b3-disubstituted butenolide carbonyl derivatives. The N,N\u2032-dioxide L2-Sc",
        "keywords": [
            ""
        ],
        "venue": "Organic Letters",
        "year": 2011,
        "id": "sOu8JShZ"
    },
    "qfTTSenz": {
        "authors": [
            {
                "name": "Liming Wu",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Lin Chen",
                "org": "School of Medicine"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Haiyang Xie",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Bajin Wei",
                "org": "School of Medicine"
            },
            {
                "name": "Shengyong Yin",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Yufu Ye",
                "org": "School of Medicine"
            },
            {
                "name": "Weijia Fang",
                "org": "Department of Medical Oncology"
            },
            {
                "name": "Shusen Zheng",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            }
        ],
        "title": "Association of interleukin 18 gene promoter polymorphisms with HBV recurrence after liver transplantation in Han Chinese population",
        "abstract": "Background: There is growing evidence suggesting that interleukin-18 (IL-18) plays a crucial role in viral clearance and disease pathogenesis, and that single nucleotide polymorphisms (SNPs) within the gene may influence its production. Objectives: To investigate the potential association of two polymorphisms (137G/C and 607C/A) in the promoter region of the IL-18 gene with the risk of HBV recurrence after liver transplantation (LT) in Han Chinese patients. Patients and Methods: IL-18 promoter genotyping was performed by the snapshot technique in 125 patients with HBV-related end-stage liver disease (ESLD) receiving LT in our center from 2004 to 2008. Results: Among the study samples, no significant association between the IL-18 promoter polymorphisms (137G/C and 607C/A) or haplotypes and HBV recurrence after LT was found. Conclusions: The polymorphisms (137G/C and 607C/A) in the promoter region of the IL- 18 gene may not play a key role in HBV recurrence after LT in Han Chinese population, and may not be suitable predictors for HBV recurrence in clinical practice. \u00a9 2011 Kowsar M.P.Co. All rights reserved.",
        "keywords": [
            "Genetic polymorphism",
            "Hepatitis",
            "Interleukin-18",
            "Recurrence",
            "Transplantation"
        ],
        "venue": "Hepatitis Monthly",
        "year": 2011,
        "id": "qfTTSenz"
    },
    "5sJHJs5G": {
        "authors": [
            {
                "name": "Yan Li",
                "org": ""
            },
            {
                "name": "Yan Zhu",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Yimin Fang",
                "org": ""
            },
            {
                "name": "Lirong Huang",
                "org": ""
            },
            {
                "name": "Liangliang Ren",
                "org": ""
            },
            {
                "name": "Yi Peng",
                "org": ""
            },
            {
                "name": "Yifen Li",
                "org": ""
            },
            {
                "name": "Fangfang Yang",
                "org": ""
            },
            {
                "name": "Dan Xie",
                "org": ""
            },
            {
                "name": "Wenzheng Tang",
                "org": ""
            },
            {
                "name": "Na Zhang",
                "org": ""
            },
            {
                "name": "Qiu Zhong",
                "org": ""
            },
            {
                "name": "Xiaomin Lai",
                "org": ""
            }
        ],
        "title": "Use of HLA-DR*08032/E7 and HLA-DR*0818/E7 tetramers in tracking of epitope-specific CD4+ T cells in active and convalescent tuberculosis patients compared with control donors",
        "abstract": "Comparative tracking of tetramer-positive and epitope-specific CD4",
        "keywords": [
            "CD4+ T cells",
            "HLA-DR8",
            "Mycobacterium tuberculosis",
            "Peptide E7",
            "Tetramer"
        ],
        "venue": "Immunobiology",
        "year": 2011,
        "id": "5sJHJs5G"
    },
    "02VMfJy4": {
        "authors": [
            {
                "name": "Hong Li",
                "org": ""
            },
            {
                "name": "Hai-yang Xie",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Shu-Sen Zheng",
                "org": ""
            }
        ],
        "title": "Lack of association of the polymorphism of the CCR5 gene in liver recipients with acute rejection from China",
        "abstract": "Objectives: This study sought to investigate the associations between polymorphisms in the chemokine receptor 5 gene and acute rejection in liver transplant. Materials and Methods: A total of 266 patients who underwent a liver transplant between January 2006 and March 2009 were enrolled in this study. Genomic DNA was extracted from whole blood, and chemokine receptor 5\u039432 was detected by polymerase chain reaction. Eight nucleotide polymorphism loci in the chemokine receptor 5 gene were detected by Applied Biosystems SNaP-Shot and TaqMan technologies. Results: Chemokine receptor 5\u039432 mutation was not detected in all the individuals from China. There was no significant association between the single nucleotide polymorphism in chemokine receptor 5 gene and acute rejection. Conclusions: Single nucleotide polymorphisms in a single gene of the chemokine receptor 5 might not play a role in acute rejection after liver transplant. \u00a9 Baskent University 2011.",
        "keywords": [
            "Acute rejection",
            "Chemokine receptor 5",
            "Chemokine receptor 5\u039432 polymorphism",
            "Liver transplant",
            "Single nucleotide polymorphism"
        ],
        "venue": "Experimental and Clinical Transplantation",
        "year": 2011,
        "id": "02VMfJy4"
    },
    "imtE9F7Z": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Ruifeng Zhang",
                "org": ""
            },
            {
                "name": "Lianfeng Zhang",
                "org": ""
            },
            {
                "name": "Weiyan Yao",
                "org": ""
            },
            {
                "name": "Jiansheng Li",
                "org": ""
            },
            {
                "name": "Yaozong Yuan",
                "org": ""
            }
        ],
        "title": "Angiotensin-converting enzyme 2 acts as a potential molecular target for pancreatic cancer therapy",
        "abstract": "Angiotensin-converting enzyme 2 (ACE2) is a novel component of the renin-angiotensin system that could counterbalance the growth-promoting function of angiotensin-converting enzyme (ACE). Our previous results have shown that ACE2 is lowly expressed in pancreas, and widely down-regulated in pancreatic cancer tissues and cells. In the present study, we investigated the effect of restoration of ACE2 expression on the growth of pancreatic cancer. We found that restoration of ACE2 protein suppressed cell proliferation, motility and increased the sensitivity to hypoxia induced injury in BxPC3 and SW1990 cell lines. Stably transfected cells overexpressing ACE2 exhibited decreased tumorigenicity and delayed tumor growth, both in vitro and in vivo. In addition, restoration of ACE2 expression mediated by adenovirus vector significantly inhibited the established tumor growth, strongly enhanced the anti-tumor activity of gemcitabine in a pancreatic cancer xenograft model in vivo, and significantly prolonged the survival time of animals bearing tumor xenografts. These results provide evidence that ACE2 plays a pivotal role in the development of pancreatic cancer, and suggest that ACE2 is a promising candidate for pancreatic cancer treatment. \u00a9 2011 Elsevier Ireland Ltd.",
        "keywords": [
            "Angiotensin-converting enzyme 2 (ACE2)",
            "Motility",
            "Pancreatic cancer",
            "Proliferation",
            "Tumorigenesis"
        ],
        "venue": "Cancer Letters",
        "year": 2011,
        "id": "imtE9F7Z"
    },
    "opBYW97C": {
        "authors": [
            {
                "name": "Zhongchun Tong",
                "org": "Department of Operative Dentistry and Endodontics"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Stomatology"
            },
            {
                "name": "Jie Li",
                "org": "Department of Preventive Dentistry"
            },
            {
                "name": "Wenkai Jiang",
                "org": "Department of Operative Dentistry and Endodontics"
            },
            {
                "name": "Lifang Ma",
                "org": "Department of Operative Dentistry and Endodontics"
            },
            {
                "name": "Longxing Ni",
                "org": "Department of Operative Dentistry and Endodontics"
            }
        ],
        "title": "In vitro evaluation of the antibacterial activities of MTAD in combination with nisin against enterococcus faecalis",
        "abstract": "Introduction: MTAD is a common intracanal irrigant. Although MTAD inhibits Enterococcus faecalis in root canals, its bactericidal effect against E. faecalis remains to be improved. Nisin, an antibacterial peptide, possesses a strong bactericidal effect. The study evaluated the synergetic action between MTAD and nisin against E. faecalis. Methods: The minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) were used to measure the antibacterial activities of MTAD, MTAN (substitution of doxycycline with nisin), and MTADN (nisin in combination with doxycycline), respectively. The synergetic effect between nisin and doxycycline was evaluated by fractional inhibitory concentration (FIC) and time-killing curves. Furthermore, morphologic changes in E. faecalis were observed by scanning electron microscopy after E. faecalis was treated with MTAD, MTAN, or MTADN for 24 hours. Results: The MBC of MTADN against E. faecalis was lower than that of MTAD and MTAN. The combination of nisin and doxycycline had a significantly synergetic antibacterial effect on E. faecalis. Among the 3 antimicrobial treatments, MTADN caused the most severe damage to E. faecalis. Conclusions: The combination of nisin and doxycycline has a synergetic antibacterial effect on E. faecalis, and MTAD in conjunction with nisin inhibits E. faecalis better than MTAD alone. Copyright \u00a9 2011 American Association of Endodontists.",
        "keywords": [
            "Enterococcus faecalis",
            "MTAD",
            "MTADN",
            "nisin"
        ],
        "venue": "Journal of Endodontics",
        "year": 2011,
        "id": "opBYW97C"
    },
    "LNBkAL1s": {
        "authors": [
            {
                "name": "Jian-Wen Jiang",
                "org": ""
            },
            {
                "name": "Zhi-Gang Ren",
                "org": ""
            },
            {
                "name": "Lu-Yan Chen",
                "org": ""
            },
            {
                "name": "Li Jiang",
                "org": ""
            },
            {
                "name": "Hai-Yang Xie",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Shu-Sen Zheng",
                "org": ""
            }
        ],
        "title": "Enteral supplementation with glycyl-glutamine improves intestinal barrier function after liver transplantation in rats",
        "abstract": "BACKGROUND: Most patients after liver transplantation (LT) suffer from intestinal barrier dysfunction. Glycyl-glutamine (Gly-Gln) by parenteral supplementation is hydrolyzed to release glutamine, which improves intestinal barrier function in intestinal injury This study aimed to investigate the effect of Gly-Gln by enteral supplementation on intestinal barrier function in rats after allogenetic LT under immunosuppressive therapy. METHODS: Twelve inbred Lewis rats were selected randomly as donors, and 24 inbred Brown Norway (BN) rats as recipients of allogenetic LT. The recipients were divided into a control group (Ala, n=12) and an experimental group (Gly-Gln, n=12). In each group, 6 normal BN rats were sampled for normal parameters on preoperative day 3. The 6 recipients in the control group received alanine (Ala) daily by gastric perfusion for 3 preoperative days and 7 postoperative days, and the 6 recipients in the experimental group were given Gly-Gln in the same manner. The 12 BN recipients underwent orthotopic LT under sterile conditions after a 3-day fast and were given immunosuppressive therapy for 7 days. They were harvested for sampling on postoperative day 8. The following parameters were assessed: intestinal mucosal protein content, mucosal ultrastructure, ileocecal sIgA content, portal plasma levels of endotoxin and TNF-a, and bacterial translocation. RESULTS: All recipients were alive after LT. On preoperative day 3, all parameters were similar in the two groups. On postoperative day 8, all parameters in the two groups were remarkably changed from those on preoperative day 3. However, compared to the Ala group, supplementation with Gly-Gln increased the levels of intestinal mucosal protein and ileocecal sIgA, improved mucosal microvilli, and decreased portal plasma levels of endotoxin and TNF-a as well as bacterial translocation. CONCLUSION: Enteral supplementation with Gly-Gln improved intestinal barrier function after allogenetic LT in rats. \u00a9 2011, Hepatobiliary Pancreat Dis Int.",
        "keywords": [
            "Bacterial translocation",
            "Glycyl-glutamine",
            "Intestinal barrier function",
            "Liver transplantation"
        ],
        "venue": "Hepatobiliary and Pancreatic Diseases International",
        "year": 2011,
        "id": "LNBkAL1s"
    },
    "uAz9YiF1": {
        "authors": [
            {
                "name": "Yuqiang Fang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Chengming Yang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Xukai Wang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Cardiology"
            },
            {
                "name": "Hongyong Wang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Chunyu Zeng",
                "org": "Department of Cardiology"
            }
        ],
        "title": "Feasibility and application of single 5F multipurpose catheter in coronary and peripheral angiography via a transradial approach",
        "abstract": "Objective: Atherosclerosis is a systemic disease, in which coronary and peripheral angiographies are required to be done at the same time in a large number of patients. To shorten the procedure time, and reduce complications, we tested the feasibility and the safety of using a single 5F multipurpose catheter, via transradial approach, for coronary, cerebral and renal angiographies. Methods: One thousand and ninety-two patients were enrolled in the study. The procedure time, local vessel complications, duration of hospitalization, and costs were evaluated. Results: Among 1092 patients, the radial artery puncture was successful in 1081 patients, a successful coronary angiography via the radial artery was done in 1074 patients, and the remaining 18 patients had to be accessed via the femoral artery. Thus, successful angiography rate was 97.7% for the right coronary artery, 95.8% for the left coronary artery, 100% for the right cerebral artery, 95.2% for the left subclavian artery, 96.1% for the left carotid artery and 83.1% for the renal artery. The failures were caused by abnormal curvature of the aortic arch and abnormal origins of the above-mentioned arteries. There were 1460 artery stenosis lesions found in 661 patients and 624 lesions (93.3%) needed stents via the transradial approach. The mean procedure time was 20.9 \u00b1 9.3 min including puncture, angiography and hemostasis time. There were 4.35% complications. No local hematoma, hand ischemia, or cerebral infraction was found in this study. Conclusion: Angiography using a single 5F multipurpose catheter, via transradial approach, is associated with a short procedure time and a low rate of complications without affecting the angiography success rate. \u00a9 2010 Elsevier Ireland Ltd.",
        "keywords": [
            "Angiography",
            "Complication",
            "Multipurpose catheter",
            "Transradial approach"
        ],
        "venue": "International Journal of Cardiology",
        "year": 2011,
        "id": "uAz9YiF1"
    },
    "JODka8iH": {
        "authors": [
            {
                "name": "Kang-Jie Chen",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Sheng-Zhang Lin",
                "org": "Department of General Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Hai-Yang Xie",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Wu-Hua Zhou",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Ahmed Taki-Eldin",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            }
        ],
        "title": "Selective recruitment of regulatory T cell through CCR6-CCL20 in hepatocellular carcinoma fosters tumor progression and predicts poor prognosis",
        "abstract": "Background: Regulatory T cells (Tregs) are highly prevalent in tumor tissue and can suppress effective anti-tumor immune responses. However, the source of the increased tumor-infiltrating Tregs and their contribution to cancer progression remain poorly understood. Methodology/Principal Finding: We here investigated the frequency, phenotype and trafficking property of Tregs and their prognostic value in patients with hepatocellular carcinoma (HCC). Our results showed that FoxP3 ",
        "keywords": [
            ""
        ],
        "venue": "PLoS ONE",
        "year": 2011,
        "id": "JODka8iH"
    },
    "E9slmUDC": {
        "authors": [
            {
                "name": "Zhen Zeng",
                "org": ""
            },
            {
                "name": "Feng Shi",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Min-Na Zhang",
                "org": ""
            },
            {
                "name": "Yan Chen",
                "org": ""
            },
            {
                "name": "Xiu-Juan Chang",
                "org": ""
            },
            {
                "name": "Yin-Ying Lu",
                "org": ""
            },
            {
                "name": "Wen-Lin Bai",
                "org": ""
            },
            {
                "name": "Jian-Hui Qu",
                "org": ""
            },
            {
                "name": "Chun-Ping Wang",
                "org": ""
            },
            {
                "name": "Hong Wang",
                "org": ""
            },
            {
                "name": "Min Lou",
                "org": ""
            },
            {
                "name": "Fu-Sheng Wang",
                "org": ""
            },
            {
                "name": "Ji-Yun Lv",
                "org": ""
            },
            {
                "name": "Yong-Ping Yang",
                "org": ""
            }
        ],
        "title": "Upregulation of circulating PD-L1/PD-1 is associated with poor post-cryoablation prognosis in patients with HBV-related hepatocellular carcinoma",
        "abstract": "Background: The programmed cell death-1 receptor/programmed cell death-1 ligand (PD-1/PD-L1) pathway plays a crucial role in tumor evasion from host immunity. This study was designed to evaluate the association between circulating PD-L1/PD-1 and prognosis after cryoablation in patients with HBV-related hepatocellular carcinoma (HCC). Methodology/Principal Findings: In the present study, 141 HBV-related HCC patients were enrolled and of those 109 patients received cryoablation. Circulating PD-L1/PD-1 expression was tested by flow cytometry, and 23 patients were simultaneously evaluated for intratumoral PD-L1 expression by immunohistochemical staining. Circulating PD-1/PD-L1 expression was associated with severity of diseases in patients with HCC, and the circulating PD-L1 expression was closely correlated with intratumoral PD-L1 expression. Of the clinical parameters, PD-1/PD-L1 expression was associated with tumor size, blood vessel invasion and BCLC staging. Moreover, PD-1/PD-L1 expression dropped after cryoablation while being elevated at the time of tumor recurrence. Patients with higher expression of circulating PD-L1, as well as circulating PD-1, had a significantly shorter overall survival and tumor-free survival than those with lower expression. Multivariate analysis confirmed that circulating PD-L1 could serve as an independent predictor of overall survival and tumor-recurrence survival in HCC patients after cryoablation. Conclusions/Significance: Upregulation of circulating PD-L1/PD-1 is associated with poor post-cryoablation prognosis in patients with HBV-related hepatocellular carcinoma. \u00a9 2011 Zeng et al.",
        "keywords": [
            ""
        ],
        "venue": "PLoS ONE",
        "year": 2011,
        "id": "E9slmUDC"
    },
    "QQu3pe4E": {
        "authors": [
            {
                "name": "Lijuan Sun",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Mingcang Chen",
                "org": ""
            },
            {
                "name": "Renqian Zhong",
                "org": ""
            },
            {
                "name": "Jianwen Liu",
                "org": ""
            }
        ],
        "title": "Amelioration of systemic lupus erythematosus by withangulatin A in MRL/lpr mice",
        "abstract": "We have previously reported the anti-inflammatory potential and the possible underlying mechanisms of Withangulatin A (WA), which is an active component isolated from Physalis angulata L. Here, we demonstrated that WA might improve the life quality, as well as reduced the accumulation of proteinuria symptoms and levels of anti-double-stranded DNA antibodies in MRL/lpr mice. Moreover, WA could improve renal histopathologic characteristics of MRL/lpr mice. Intriguingly, expression of B cell-activating factor (BAFF), BAFF-R and related gene in the spleen were significantly reduced in 10mg/kg WA-treated mice compared with that in 5mg/kg WA-treated mice and untreated mice. These findings indicate that WA might have a pleiotropic therapeutic effect through their immunosuppression via inhibiting BAFF signaling, which suggest a potential application of this active constituent in the treatment of SLE. Copyright \u00a9 2011 Wiley-Liss, Inc.",
        "keywords": [
            "BAFF",
            "Mrl/Lpr mice",
            "systemic lupus erythematosus",
            "Withangulatin A"
        ],
        "venue": "Journal of Cellular Biochemistry",
        "year": 2011,
        "id": "QQu3pe4E"
    },
    "ALH2o79Q": {
        "authors": [
            {
                "name": "Junjie Li",
                "org": "Campus Gasthuisberg"
            },
            {
                "name": "Ziping Sun",
                "org": "Shandong Academy of Medical Sciences"
            },
            {
                "name": "Jian Zhang",
                "org": "Jiangsu Academy of Traditional Chinese Medicine"
            },
            {
                "name": "Haibo Shao",
                "org": "China Medical University"
            },
            {
                "name": "Marlein Miranda Cona",
                "org": "Campus Gasthuisberg"
            },
            {
                "name": "Huaijun Wang",
                "org": "Campus Gasthuisberg"
            },
            {
                "name": "Thierry Marysael",
                "org": "Campus Gasthuisberg"
            },
            {
                "name": "Feng Chen",
                "org": "Southeast University"
            },
            {
                "name": "Kristof Prinsen",
                "org": "Campus Gasthuisberg"
            },
            {
                "name": "Lin Zhou",
                "org": "Campus Gasthuisberg"
            },
            {
                "name": "Dejian Huang",
                "org": "Jiangsu Academy of Traditional Chinese Medicine"
            },
            {
                "name": "Johan Nuyts",
                "org": "Campus Gasthuisberg"
            },
            {
                "name": "Jie Yu",
                "org": "Campus Gasthuisberg"
            },
            {
                "name": "Bin Meng",
                "org": "Shandong Academy of Medical Sciences"
            },
            {
                "name": "Guy Bormans",
                "org": "Campus Gasthuisberg"
            },
            {
                "name": "Zhijun Fang",
                "org": "Jiangsu Academy of Traditional Chinese Medicine"
            },
            {
                "name": "Peter De Witte",
                "org": "Campus Gasthuisberg"
            },
            {
                "name": "Yaming Li",
                "org": "China Medical University"
            },
            {
                "name": "Alfons Verbruggen",
                "org": "Campus Gasthuisberg"
            },
            {
                "name": "Xiaoning Wang",
                "org": "Jiangsu Academy of Traditional Chinese Medicine"
            },
            {
                "name": "Luc Mortelmans",
                "org": "Campus Gasthuisberg"
            },
            {
                "name": "Ke Xu",
                "org": "China Medical University"
            },
            {
                "name": "Guy Marchal",
                "org": "Campus Gasthuisberg"
            },
            {
                "name": "Yicheng Ni",
                "org": "Southeast University"
            }
        ],
        "title": "A dual-targeting anticancer approach: Soil and seed principle",
        "keywords": [
            ""
        ],
        "venue": "Radiology",
        "year": 2011,
        "id": "ALH2o79Q"
    },
    "HrlyLeDt": {
        "authors": [
            {
                "name": "Li-Shuai Wang",
                "org": ""
            },
            {
                "name": "Yu Zhang",
                "org": ""
            },
            {
                "name": "Xiao-Jun Lu",
                "org": ""
            },
            {
                "name": "Hua-Jun Lu",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Yong-Sheng Wang",
                "org": ""
            },
            {
                "name": "Lei Deng",
                "org": ""
            },
            {
                "name": "Mei-Juan Huang",
                "org": ""
            },
            {
                "name": "Feng Peng",
                "org": ""
            },
            {
                "name": "Jin Wang",
                "org": ""
            },
            {
                "name": "Li Ren",
                "org": ""
            },
            {
                "name": "Mei Hou",
                "org": ""
            },
            {
                "name": "Lu Li",
                "org": ""
            },
            {
                "name": "Yong Xu",
                "org": ""
            },
            {
                "name": "Bin-Wu Ying",
                "org": ""
            },
            {
                "name": "You Lu",
                "org": ""
            }
        ],
        "title": "Detection of epidermal growth factor receptor gene mutations in non-small cell lung cancer using bi-loop probe specific primer quantitative PCR",
        "abstract": "Objective To investigate the sensitivity of bMoop probe and specific primer quantitative PCR (BPSP-qPCR) in the detection of epidermal growth factor receptor (EGFR) gene mutations in nonsmall cell lung cancer ( NSCLC ). Methods BPSP-qPCR was employed to examine the presence of mutations of EFGR exon 19 through 21. Correlation of the mutations with clinicopathological characteristics and types of tumor samples were performed. Results In the cohort of 265 specimens, 30. 2% ( 80/265 ) mutations were found to be 19-del and/or L858R. Females ( 39. 7% , 31/78 ) , non-smokers (41.0%, 43/105) and adenocarcinoma patients (37. 8% ,51/135) had a higher mutation rate (P <0. 05) among 184 patients whose profiles were available. T790M combined with 19-del and/or L858R accounted for 3. 3% (6/184) of the mutations. Male metastatic tumors (29.6% ,8/27) , pleural fluids of females (42.9% , 9/21) and non-smokers (40.7% ,11/27) were found to have higher percentage of 19-del and/or L858R mutations, in contrast, no mutations were found in the metastatic lesions of non-adenocarcinoma patients ( P > 0. 05 ). Conclusions BPSP-qPCR is a robust method in detection of EGFR mutations with high consistency and sensitivity. The difference of EGFR mutations in primary tumors, metastatic lesions and pleural fluids suggests that EGFR tyrosine kinase inhibitors ( EGFR-TKI ) treatment may have variable treatment effects depending on the tumor sites.",
        "keywords": [
            "Carcinoma, non-small-cell lung",
            "Polymerase chain reaction",
            "Receptor, epidermal growth factor"
        ],
        "venue": "Chinese Journal of Pathology",
        "year": 2011,
        "id": "HrlyLeDt"
    },
    "Xvpw9qed": {
        "authors": [
            {
                "name": "Zhongchun Tong",
                "org": "Department of Operative Dentistry and Endodontics"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Stomatology"
            },
            {
                "name": "Wenkai Jiang",
                "org": "Department of Operative Dentistry and Endodontics"
            },
            {
                "name": "Rong Kuang",
                "org": "Department of Operative Dentistry and Endodontics"
            },
            {
                "name": "Jie Li",
                "org": "Department of Preventive Dentistry"
            },
            {
                "name": "Rui Tao",
                "org": "Department of Operative Dentistry and Endodontics"
            },
            {
                "name": "Longxing Ni",
                "org": "Department of Operative Dentistry and Endodontics"
            }
        ],
        "title": "An in vitro synergetic evaluation of the use of nisin and sodium fluoride or chlorhexidine against Streptococcus mutans",
        "abstract": "The objective of this study is to investigate the synergetic action between nisin and sodium fluoride or chlorhexidine against Streptococcus mutans, a primary cariogenic pathogen. In the antibacterial assay, a synergetic effect on S. mutans was found between nisin and sodium fluoride, but there was no interaction between nisin and chlorhexidine by the checkerboard, the fractional inhibitory concentration (FIC) and the fractional bactericidal concentration (FBC) tests. S. mutans survival rates showed a significant decline after treatment with a combination of nisin and sodium fluoride in a time-kill study. Scanning electron microscopy showed that the damage to S. mutans with the combined nisin and sodium fluoride treatment was the most severe among all of the different single and combined antimicrobial treatments. Furthermore, in the antibiofilm test, nisin in combination with sodium fluoride produced a stronger bactericidal effect on a S. mutans biofilm for 4 h and 16 h compared with sodium fluoride alone by confocal laser scanning microscopy. Nisin in combination with sodium fluoride exerted a high bactericidal effect on S. mutans and thereby has the potential to be used as an effective drug combination to prevent dental caries. \u00a9 2011 Elsevier Inc. All rights reserved.",
        "keywords": [
            "Chlorhexidine",
            "Nisin",
            "Sodium fluoride",
            "Streptococcus mutans",
            "Synergy"
        ],
        "venue": "Peptides",
        "year": 2011,
        "id": "Xvpw9qed"
    },
    "gYsCAgiz": {
        "authors": [
            {
                "name": "Xiaoqin Jiang",
                "org": "Radiation Physics Center"
            },
            {
                "name": "Tao Li",
                "org": "Radiation Physics Center"
            },
            {
                "name": "Yongmei Liu",
                "org": "Department of Thoracic Oncology and Radiation Oncology"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Thoracic Oncology and Radiation Oncology"
            },
            {
                "name": "Yong Xu",
                "org": "Department of Thoracic Oncology and Radiation Oncology"
            },
            {
                "name": "Xiaojuan Zhou",
                "org": "Department of Thoracic Oncology and Radiation Oncology"
            },
            {
                "name": "Youling Gong",
                "org": "State Key Laboratory of Biotherapy"
            }
        ],
        "title": "Planning analysis for locally advanced lung cancer: Dosimetric and efficiency comparisons between intensity-modulated radiotherapy (IMRT), single-arc/partial-arc volumetric modulated arc therapy (SA/PA-VMAT)",
        "abstract": "Purpose: To analyze the differences between the intensity-modulated radiotherapy (IMRT), single/partial-arc volumetric modulated arc therapy (SA/PA-VMAT) techniques in treatment planning for locally advanced lung cancer.Materials and methods: 12 patients were retrospectively studied. In each patient's case, several parameters were analyzed based on the dose-volume histograms (DVH) of the IMRT, SA/PA-VMAT plans respectively. Also, each plan was delivered to a phantom for time comparison.Results: The SA-VMAT plans showed the superior target dose coverage, although the minimum/mean/maximum doses to the target were similar. For the total and contralateral lungs, the higher V",
        "keywords": [
            "Intensity-modulated radiotherapy",
            "Lung cancer",
            "Normal tissue toxicity",
            "Target dose distribution",
            "Volumetric modulated arc therapy"
        ],
        "venue": "Radiation Oncology",
        "year": 2011,
        "id": "gYsCAgiz"
    },
    "6Kt9nqLe": {
        "authors": [
            {
                "name": "Zhi-Gang Ren",
                "org": "Key Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Hui Liu",
                "org": "Institute of Immunology"
            },
            {
                "name": "Jian-Wen Jiang",
                "org": "Key Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Li Jiang",
                "org": "Key Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Hui Chen",
                "org": "Key Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Hai-Yang Xie",
                "org": "Key Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Key Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health"
            }
        ],
        "title": "Protective effect of probiotics on intestinal barrier function in malnourished rats after liver transplantation",
        "abstract": "BACKGROUND: Most patients waiting for liver transplantation have end-stage liver diseases with malnutrition, which is prone to induce intestinal barrier dysfunction after liver transplantation. We aimed to study the effect of probiotics on intestinal barrier function in malnourished rats following liver transplantation with long-term antibiotics. METHODS: Twelve Lewis rats were selected as donors. Twelve BN rats, which served as recipients, were subjected to malnutrition by semi-starvation for 4-5 weeks. They were randomly divided into two groups: a control group which received phosphate-buffered saline and a probiotics group which received Bifidobacterium and Lactobacillus. All recipients were injected with intramuscular imipenem and subcutaneous cyclosporine A. Furthermore, six normal BN rats without any drugs or operations served as a normal group. Eight days after operation, all rats were sacrificed for examination of the following parameters: serum levels of endotoxin and TNF-\u03b1, bacterial translocation, intestinal microflora, ileocecal sIgA, lymphocyte numbers, and phenotypes (CD4, CD8, \u03b1\u03b2TCR, \u03b3\u03b4TCR) of Peyer's patches. RESULTS: In recipients subjected to malnutrition, weight decreased by 20% and they survived until 8 days after operation. Compared with the normal group, all recipients on postoperative day 8 showed increased levels of serum endotoxin and TNF-\u03b1 as well as increased counts of translocated bacteria. Meanwhile, there were decreases in counts of Bifidobacterium and Lactobacillus in the ileocecum, sIgA concentration, and lymphocytes of Peyer's patches. Moreover, partial alteration in lymphocyte phenotypes was evidenced by elevated ratios of CD8 ",
        "keywords": [
            "Intestinal barrier function",
            "Intestinal microflora",
            "Liver transplantation",
            "Probiotics"
        ],
        "venue": "Hepatobiliary and Pancreatic Diseases International",
        "year": 2011,
        "id": "6Kt9nqLe"
    },
    "iyNyxQMX": {
        "authors": [
            {
                "name": "Xiaobo Yu",
                "org": "Key Lab of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Haiyang Xie",
                "org": "Key Lab of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Bajin Wei",
                "org": "Key Lab of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Min Zhang",
                "org": "Department of Surgery, Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Weilin Wang",
                "org": "Department of Surgery, Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Jian Wu",
                "org": "Department of Surgery, Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Sheng Yan",
                "org": "Department of Surgery, Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Shusen Zheng",
                "org": "Department of Surgery, Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Lab of Combined Multi-Organ Transplantation"
            }
        ],
        "title": "Association of MDR1 gene SNPs and haplotypes with the tacrolimus dose requirements in Han Chinese liver transplant recipients",
        "keywords": [
            ""
        ],
        "venue": "PLoS ONE",
        "year": 2011,
        "id": "iyNyxQMX"
    },
    "qbBzRkE1": {
        "authors": [
            {
                "name": "Zhongchun Tong",
                "org": ""
            },
            {
                "name": "Rui Tao",
                "org": ""
            },
            {
                "name": "Wenkai Jiang",
                "org": ""
            },
            {
                "name": "Jie Li",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Yu Tian",
                "org": ""
            },
            {
                "name": "Longxing Ni",
                "org": ""
            }
        ],
        "title": "In vitro study of the properties of Streptococcus mutans in starvation conditions",
        "abstract": "Objectives: The present study is to assess Streptococcus mutans survivability in different starvation conditions and to determine the resistance of starved S. mutans to lethal acid and two common anti-caries agents, sodium fluoride (NaF) and chlorhexidine acetate (CHX). Methods: S. mutans survival rates in sterile water, PBS, sterile saliva, 1/5 strength BHI and BHI were determined at a given time by plate count of viable cell. The resistance of starved S. mutans and control S. mutans to four times the minimal bactericidal concentration (MBC) of NaF, two times the MBC of CHX and acid (pH 2.8) was evaluated and compared respectively. Furthermore, field emission scanning electron microscope (FE-SEM) was used to observe the morphologic characteristics of the starved S. mutans cells. Results: S. mutans showed starvation tolerance under five different starvation conditions, but the bacterial survival rates were different at the same time points. The starved S. mutans exhibited significantly higher resistance (p < 0.05) to challenge by anti-caries agents and acid than the control S. mutans. Additionally, starvation resulted in the morphologic modification of S. mutans, and the disruptive degree depended on the change in time. Conclusion: The present study indicates that S. mutans displays starvation tolerance, and starvation decreased the susceptibility of S. mutans to NaF, CHX and acid. \u00a9 2011 Elsevier Ltd. All rights reserved.",
        "keywords": [
            "Chlorhexidine acetate",
            "Sodium fluoride",
            "Starvation",
            "Streptococcus mutans"
        ],
        "venue": "Archives of Oral Biology",
        "year": 2011,
        "id": "qbBzRkE1"
    },
    "Um9lxcip": {
        "authors": [
            {
                "name": "Ying Hou",
                "org": ""
            },
            {
                "name": "Qidong Yang",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Xiaoping Du",
                "org": ""
            },
            {
                "name": "Min Li",
                "org": ""
            },
            {
                "name": "Mei Yuan",
                "org": ""
            },
            {
                "name": "Zhiwen Zhou",
                "org": ""
            },
            {
                "name": "Zhenguo Li",
                "org": ""
            }
        ],
        "title": "Tetrahydroxystilbene glucoside improves learning and (or) memory ability of aged rats and may be connected to the APP pathway",
        "abstract": "The aim of this study is to evaluate the protective effects of 2,3,5,4\u0301-tetrahydroxystilbene-2-O-\u03b2-D-glucoside (TSG) on learning and (or) memory deficit in aged rats, as well as to explore the possible connection between TSG and the \u03b2-amyloid precursor protein (APP) pathway. Sprague-Dawley rats were randomly divided into a young control group (age, 4 months), an aged control group (age, 22 months), and a TSG-treated group (age, 22 months). TSG at doses of 50 mg\u00b7kg ",
        "keywords": [
            "A disintegrin and metalloproteinase 10 (adam10)",
            "Aging",
            "APP cleaving enzyme (appce)",
            "Beta-site APP cleaving enzyme 1 (bace1)",
            "Tetrahydroxystilbene glucoside (tsg)"
        ],
        "venue": "Canadian Journal of Physiology and Pharmacology",
        "year": 2011,
        "id": "Um9lxcip"
    },
    "FfWst5TX": {
        "authors": [
            {
                "name": "Ahmed Taki-Eldin",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Hai-Yang Xie",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Kang-Jie Chen",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Wu-Hua Zhou",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Wu Zhang",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Chun-Yang Xing",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Zhe Yang",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Kai Zhang",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            }
        ],
        "title": "Tri-iodothyronine enhances liver regeneration after living donor liver transplantation in rats",
        "abstract": "Background: Tri-iodothyronine (T3) has been shown to be a hepatic mitogen. The aim of this study was to evaluate the effect of T3 on liver regeneration after 50% partial liver transplantation (pLT) in rats. Methods: Immediately after pLT, a single dose of T3 (4 mg/kg body weight) was administered. Liver/body weight ratio (LBWR), hepatocyte proliferation (Ki-67), biochemical parameters, and changes in cell cycle related proteins were evaluated. Results: T3 promoted liver regeneration as shown by an increased liver/body weight ratio and Ki-67 proliferation index after pLT. On the transcriptional level, T3-treated rats had an increased expression of cyclin D1 and cyclin A as demonstrated by real time RT-PCR and Western blot. Conclusions: Exogenous administration of T3 significantly improved liver regeneration after pLT, and therefore it may represent a promising strategy to improve the clinical outcome after living donor liver transplantation in the future. \u00a9 2011 Japanese Society of Hepato-Biliary-Pancreatic Surgery and Springer.",
        "keywords": [
            "Cell cycle",
            "Hepatic mitogen",
            "Liver regeneration",
            "Liver transplantation",
            "T3"
        ],
        "venue": "Journal of Hepato-Biliary-Pancreatic Sciences",
        "year": 2011,
        "id": "FfWst5TX"
    },
    "LXV3bDFe": {
        "authors": [
            {
                "name": "Xiao Xu",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Zhenhua Tu",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Bei Wang",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Qi Ling",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Lin Zhang",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Guoping Jiang",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Jian Wu",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Shusen Zheng",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation"
            }
        ],
        "title": "A novel model for evaluating the risk of hepatitis B recurrence after liver transplantation",
        "keywords": [
            "Hepatitis B recurrence",
            "Liver transplantation",
            "Model",
            "Related risk factors"
        ],
        "venue": "Liver International",
        "year": 2011,
        "id": "LXV3bDFe"
    },
    "AjlZYOYK": {
        "authors": [
            {
                "name": "Jian Yang",
                "org": "Department of Cardiology"
            },
            {
                "name": "Yu Han",
                "org": "Department of Cardiology"
            },
            {
                "name": "Hailan Sun",
                "org": "Department of Nutrition"
            },
            {
                "name": "Caiyu Chen",
                "org": "Department of Cardiology"
            },
            {
                "name": "Duofen He",
                "org": "Department of Cardiology"
            },
            {
                "name": "Jing Guo",
                "org": "Department of Nutrition"
            },
            {
                "name": "Changqing Yu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Baoquan Jiang",
                "org": "Department of Nutrition"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Cardiology"
            },
            {
                "name": "Chunyu Zeng",
                "org": "Department of Cardiology"
            }
        ],
        "title": "(-)-Epigallocatechin gallate suppresses proliferation of vascular smooth muscle cells induced by high glucose by inhibition of PKC and ERK1/2 signalings",
        "abstract": "Proliferation of vascular smooth muscle cells (VSMCs) plays an important role in the development and progression of diabetes-related vascular complications. (-)-Epigallocatechin gallate (EGCG), the major catechin derived from green tea, is able to exert antidiabetes effects in animal models. However, it is not known whether or not EGCG inhibits VSMC proliferation induced by high glucose. This study tested the hypothesis that EGCG might have an inhibitory effect on VSMC proliferation induced by high glucose. VSMC proliferation was determined by [ ",
        "keywords": [
            "EGCG",
            "high glucose",
            "proliferation",
            "vascular smooth muscle cells"
        ],
        "venue": "Journal of Agricultural and Food Chemistry",
        "year": 2011,
        "id": "AjlZYOYK"
    },
    "0DOwyRCH": {
        "authors": [
            {
                "name": "Xin-Xing Zhang",
                "org": ""
            },
            {
                "name": "Mei-Juan Huang",
                "org": ""
            },
            {
                "name": "You-Ling Gong",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Yong-Mei Liu",
                "org": ""
            },
            {
                "name": "Jiang Zhu",
                "org": ""
            }
        ],
        "title": "A retrospective study of pemetrexed combined with oxaliplatin as second-line treatment for advanced non-small-cell lung cancer: Comparable toxicity, better outcome",
        "abstract": "Background: The outcomes of single-agent regimens as second-line chemotherapy for metastatic non-small-cell lung cancer (NSCLC) are poor. Pemetrexed combined with oxaliplatin has been reportedly well-tolerated and active in chemotherapy-na\u00efve NSCLC. The current study aimed to evaluate the therapeutic effect and toxicity of the regimen of pemetrexed plus oxaliplatin for pretreated advanced NSCLC. Patients and methods: The clinical records of consecutive patients with metastatic NSCLC who received pemetrexed after failed first-line chemotherapy were reviewed. Results: The medical records of 79 eligible patients were examined. Thirty-four of them were treated with a regimen of pemetrexed plus oxaliplatin (PEMOX). Another 45 patients were administered pemetrexed alone (PEM). Both regimens were well-tolerated and there was no therapy-related death. Comparable response rates (15.2% vs. 11.1%) and tumor control rates (63.6% vs. 47.5%) were observed between the two groups. Median time to progression and overall survival of the PEMOX and PEM groups were 18 weeks (95% confidence interval (CI): 13.72-22.28 weeks) versus 13 weeks (95%CI: 12.28-13.72 weeks; P= 0.002), and 31 weeks (95%CI: 15.56-46.44 weeks) versus 21 weeks (95%CI: 18.37-23.63 weeks; P= 0.006), respectively. Conclusions: The current retrospective study suggests that pemetrexed combined with oxaliplatin as second-line treatment for advanced NSCLC has comparable safety and response with a pemetrexed alone regimen, but better survival. \u00a9 Tianjin Lung Cancer Institute and Blackwell Publishing Asia Pty. Ltd.",
        "keywords": [
            "NSCLC",
            "Oxaliplatin",
            "Pemetrexed",
            "Second line"
        ],
        "venue": "Thoracic Cancer",
        "year": 2011,
        "id": "0DOwyRCH"
    },
    "V9YETbo9": {
        "authors": [
            {
                "name": "Jun Cheng",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Hai-Yang Xie",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Xiao Xu",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Jian Wu",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Xuyong Wei",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Rong Su",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Wu Zhang",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Zhen Lv",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "S. Zheng Shusen",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            }
        ],
        "title": "NDRG1 as a biomarker for metastasis, recurrence and of poor prognosis in hepatocellular carcinoma",
        "keywords": [
            "Biomarker",
            "Hepatocellular carcinoma",
            "Metastasis",
            "NDRG1",
            "Recurrence"
        ],
        "venue": "Cancer Letters",
        "year": 2011,
        "id": "V9YETbo9"
    },
    "5y3lYnqs": {
        "authors": [
            {
                "name": "Baiye Jin",
                "org": "Department of Urology"
            },
            {
                "name": "Guanghou Fu",
                "org": "Department of Urology"
            },
            {
                "name": "Hao Pan",
                "org": "Department of Urology"
            },
            {
                "name": "Xiaofei Cheng",
                "org": "Ministry of Public Health"
            },
            {
                "name": "Lin Zhou",
                "org": "Ministry of Public Health"
            },
            {
                "name": "Jia Lv",
                "org": "Department of Urology"
            },
            {
                "name": "Geming Chen",
                "org": "Department of Urology"
            },
            {
                "name": "Shusen Zheng",
                "org": "First Affiliated Hospital"
            }
        ],
        "title": "Anti-tumour efficacy of mitofusin-2 in urinary bladder carcinoma",
        "abstract": "Mitochondrial GTPase mitofusin-2 gene (Mfn2) is a novel gene characterised as a cell proliferation inhibitor. Mfn2 protein over-expression, mediated by an adenovirus, has a significant anti-tumour effect in A548 and HT-29 cells. However, there is no report on the effect of Mfn2 on urinary bladder carcinoma (UBCC). In this study, we sought to investigate the function of Mfn2 in UBCC. Mfn2 expression in 36 paired UBCC samples was investigated by reverse transcription-polymerase chain reaction and Western blot analyses. An adenovirus encoding the complete Mfn2 open reading frame (Ad-Mfn2) was used to infect UBCC cells, and an adenoviral vector encoding green fluorescent protein (Ad-GFP) was used as a control. The effects of Mfn2 on cell-cycle distribution and apoptosis were assessed by flow cytometry and Western blot analyses. The Mfn2 protein showed significantly lower expression in UBCC tissues than nearby non-tumourous tissues. Ad-Mfn2 exhibited a significant anti-tumour effect in T24 and 5,637 cells. Mfn2 overexpression in T24 cells significantly inhibited cell proliferation, by arresting the transition of the cell cycle from the G ",
        "keywords": [
            "Adenovirus",
            "Anti-tumour",
            "Biomarkers",
            "Cell cycle",
            "Mitofusin-2",
            "Urinary bladder carcinoma"
        ],
        "venue": "Medical Oncology",
        "year": 2011,
        "id": "5y3lYnqs"
    },
    "a3QNwbuv": {
        "authors": [
            {
                "name": "Xiao Xu",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Qiang Wei",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Kai Wang",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Qi Ling",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Haiyang Xie",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Shusen Zheng",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            }
        ],
        "title": "Anticancer effects of Huaier are associated with down-regulation of P53",
        "abstract": "This study was designed to explore the mechanism of Huaier anticancer effects on experimental hepatocellular cancer (HCC) development. Seventy five rats were divided into 5 groups, administered N-nitrosodiethylamine (groups B, C, D and E) or natural saline (group A). Rats in group C and E were also given Huaier. At the 15 week sacrifice point, the HCC incidence of group C was lower than group correlating with serum AFP. The serum ALT concentration (98.9% greater) and P53 mRNA levels (23.2%) were higher in Group B than group C. Longer term survival rates between group D and E were not significantly different. Huaier can protect liver from chemical injury and furthermore HCC development, possibly with involvement of down-regulation of P53.",
        "keywords": [
            "Animal model",
            "Anticancer effect",
            "Hepatocellular carcinoma",
            "Huaier"
        ],
        "venue": "Asian Pacific Journal of Cancer Prevention",
        "year": 2011,
        "id": "a3QNwbuv"
    },
    "VglT1sfP": {
        "authors": [
            {
                "name": "Hong Li",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Hai-Yang Xie",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Wei-Lin Wang",
                "org": "Division of Hepatobiliary Pancreatic Surgery"
            },
            {
                "name": "Ting-Bo Liang",
                "org": "Division of Hepatobiliary Pancreatic Surgery"
            },
            {
                "name": "Min Zhang",
                "org": "Division of Hepatobiliary Pancreatic Surgery"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Division of Hepatobiliary Pancreatic Surgery"
            }
        ],
        "title": "Polymorphisms of CCL3L1/CCR5 genes and recurrence of hepatitis B in liver transplant recipients",
        "abstract": "The genetic diversity of chemokines and chemokine receptors has been associated with the outcome of hepatitis B virus infection. The aim of this study was to evaluate whether the copy number variation in the CCL3L1 gene and the polymorphisms of CCR5\u039432 and CCR5-2459A\u2192G (rs1799987) are associated with recurrent hepatitis B in liver transplantation for hepatitis B virus infection-related end-stage liver disease. METHODS: A total of 185 transplant recipients were enrolled in this study. The genomic DNA was extracted from whole blood, the copy number of the CCL3L1 gene was determined by a quantitative real-time PCR based assay, CCR5\u039432 was detected by a sizing PCR method, and a single-nucleotide polymorphism in CCR5-2459 was detected by restriction fragment length polymorphism PCR. RESULTS: No CCR5\u039432 mutation was detected in any of the individuals from China. Neither copy number variation nor polymorphism in CCR5-2459 was associated with posttransplant re-infection with hepatitis B virus. However, patients with fewer copies (<4) of the CCL3L1 gene compared with the population median in combination with the CCR5G allele had a significantly higher risk for recurrent hepatitis B (odds ratio=1.93, 95% CI: 1.00-3.69; P=0.047). CONCLUSION: Patients possessing the compound decreased functional genotype of both CCL3L1 and CCR5 genes might be more likely to have recurrence of hepatitis B after transplantation. \u00a9 2011, Hepatobiliary Pancreat Dis Int. All rights reserved.",
        "keywords": [
            "CCL3L1",
            "Chemokine receptor 5",
            "Copy number variation",
            "Hepatitis B",
            "Liver transplantation"
        ],
        "venue": "Hepatobiliary and Pancreatic Diseases International",
        "year": 2011,
        "id": "VglT1sfP"
    },
    "bV9hsNRU": {
        "authors": [
            {
                "name": "Tianxiang Chen",
                "org": ""
            },
            {
                "name": "Dongli Song",
                "org": ""
            },
            {
                "name": "Zhihui Min",
                "org": ""
            },
            {
                "name": "Xiangdong Wang",
                "org": ""
            },
            {
                "name": "Yu Gu",
                "org": ""
            },
            {
                "name": "Bajin Wei",
                "org": ""
            },
            {
                "name": "Jia Yao",
                "org": ""
            },
            {
                "name": "Kangjie Chen",
                "org": ""
            },
            {
                "name": "Zhijun Jiang",
                "org": ""
            },
            {
                "name": "Haiyang Xie",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Shusen Zheng",
                "org": ""
            }
        ],
        "title": "Perioperative dynamic alterations in peripheral regulatory T and B cells in patients with hepatocellular carcinoma",
        "abstract": "Background: Intratumoral and circulating regulatory T cells (Tregs) have been shown to be critical in the pathogenesis of hepatocellular carcinoma (HCC). However there is limited knowledge on the alterations of regulatory B cells (Bregs). We here investigated perioperative dynamic alterations of peripheral circulating Tregs and Bregs in HCC patients to reveal the relationship between regulatory lymphocytes and its clinical implications.Methods: 36 patients with HCC, 6 with chronic hepatitis B infection and 10 healthy donors were enrolled for this study. Frequencies of peripheral Tregs and Bregs were measured by flow cytometry with antibodies against CD4, CD25, CD127, CD19 and IL-10 before, and after radical surgery. Then, clinical informatics of HCC patients was achieved through Digital Evaluation Score System (DESS) for the assessment of disease severity. Finally, we analysed correlations between digitalized clinical features and kinetics of circulating regulatory lymphocytes.Results: Level of circulating CD4 ",
        "keywords": [
            "Clinical informatics",
            "Dynamic alteration",
            "Hepatocellular carcinoma",
            "Lymphocytes",
            "Regulatory b cells",
            "Regulatory t cells",
            "Surgery"
        ],
        "venue": "Journal of Translational Medicine",
        "year": 2012,
        "id": "bV9hsNRU"
    },
    "vN1U530C": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Chun-Ping Wang",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Yin-Ying Lu",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Wen-Lin Bai",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Jian-Hui Qu",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Min Lou",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Zhen Zeng",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Yu Wu",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Yan Chen",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Hong Wang",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Xiu-Juan Chang",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Yong-Ping Yang",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            }
        ],
        "title": "Decrease in size of non-treated lesions after cryoablation for hepatocellular carcinoma",
        "abstract": "We present the case of one 58-year-old man with advancd hepatocellular carcinoma and hepatitis-B virus-related liver cirrhosis who received hepatic cryoablation. Magnetic resonance imaging (MRI) showed multiple liver tumors and the diameter of the largest tumor was more than 10cm. The patient received 2 percutaneous cryoablations in December 2009 and January 2010. Ten months later, MRI showed that not only the treated areas underwent necrosis but also the non-treated area decreased. The \u03b1-fetoprotein (AFP) level and the frequency of circulated regulatory T cell (Treg) before treatment were 13,800ng/mL and 15.6%, respectively. Following the cryoablations they dropped to 436ng/mL and 7.6%, respectively, 10 months later. The patient remains in good condition until now. \u00a9 H.G.E. Update Medical Publishing S.A.",
        "keywords": [
            "Cryoablation",
            "Cryoimmunology",
            "Liver tumor"
        ],
        "venue": "Hepato-Gastroenterology",
        "year": 2012,
        "id": "vN1U530C"
    },
    "mGMmbwyZ": {
        "authors": [
            {
                "name": "Lei Deng",
                "org": ""
            },
            {
                "name": "Yuan Tang",
                "org": ""
            },
            {
                "name": "Jing Lin",
                "org": ""
            },
            {
                "name": "Xiao-Jun Lu",
                "org": ""
            },
            {
                "name": "Jian-Xin Xue",
                "org": ""
            },
            {
                "name": "Li-Shuai Wang",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Yan Zou",
                "org": ""
            },
            {
                "name": "Bin-Wu Ying",
                "org": ""
            },
            {
                "name": "Gan-Di Li",
                "org": ""
            },
            {
                "name": "You Lu",
                "org": ""
            }
        ],
        "title": "Detection of epidermal growth factor receptor gene mutation in non-small cell lung cancer by allele-specific oligonucleotide-PCR and bi-loop probe specific primer quantitative PCR",
        "abstract": "Objective To compare the detection sensitivity of epidermal growth factor receptor (EGFR) mutations between allele specific oligonucleotide PCR(ASO-PCR) and bi-loop probe and specific primer quantitative PCR (BPSP-qPCR). Methods A total of 96 non-small cell lung cancer specimens were selected from West China Hospital from September 2009 to December 2010. ASO-PCR was developed to detect the presence of classical EGFR mutations. A total 39 available specimens were also tested by BPSPqPCR. Results EGFR mutation detection rate was 30. 2% (26/96) by ASO-PCR. The mutation rate was higher in female than in male patients[45. 5% (20/44) vs. 17.3% (9/52), P = 0.003] , non-smokers than smokers[44.1% (26/59) vs. 8.1% (3/37), P <0.001 ] and adenocarcinomas than other subtypes of lung cancer [37.0% (27/73) vs. 8.7% (2/23), P = 0.01]. Among mutation negative cases by ASO-PCR, BPSP-qPCR increased the rate of detection of 19-del and L858R mutation by 10.3% (4/39) in adenocarcinomas and non-smoking subset. Overall, the mutation detection rate of BPSP-qPCR was higher than that of ASO-PCR [66.7% (26/39) vs. 41.0% (16/39), P =0.02]. Conclusion BPSP-qPCR has a better detection sensitivity than that of ASO-PCR.",
        "keywords": [
            "Carcinoma",
            "Epidermal growth factor",
            "Non-small-cell lung",
            "Polymerase chain reaction",
            "Receptor"
        ],
        "venue": "Chinese Journal of Pathology",
        "year": 2012,
        "id": "mGMmbwyZ"
    },
    "wbAtNcmn": {
        "authors": [
            {
                "name": "Sheng Yan",
                "org": "Key Laboratory of Organ Transplantation Zhejiang Province"
            },
            {
                "name": "Yuan Ding",
                "org": "Key Laboratory of Organ Transplantation Zhejiang Province"
            },
            {
                "name": "Fei Sun",
                "org": "Key Laboratory of Organ Transplantation Zhejiang Province"
            },
            {
                "name": "Zhongjie Lu",
                "org": "Key Laboratory of Organ Transplantation Zhejiang Province"
            },
            {
                "name": "Liang Xue",
                "org": "Key Laboratory of Organ Transplantation Zhejiang Province"
            },
            {
                "name": "Xiangyan Liu",
                "org": "Key Laboratory of Organ Transplantation Zhejiang Province"
            },
            {
                "name": "Mingqi Shuai",
                "org": "Key Laboratory of Organ Transplantation Zhejiang Province"
            },
            {
                "name": "Chen Fang",
                "org": "Key Laboratory of Organ Transplantation Zhejiang Province"
            },
            {
                "name": "Yan Wang",
                "org": "Key Laboratory of Organ Transplantation Zhejiang Province"
            },
            {
                "name": "Hui Cheng",
                "org": "Key Laboratory of Organ Transplantation Zhejiang Province"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Organ Transplantation Zhejiang Province"
            },
            {
                "name": "Ming H Zheng",
                "org": "Centre for Orthopaedic Research"
            },
            {
                "name": "Shusen Zheng",
                "org": "Key Laboratory of Organ Transplantation Zhejiang Province"
            }
        ],
        "title": "Pretreatment of Cisplatin in recipients attenuates Post-Transplantation Pancreatitis in murine model",
        "abstract": "Pancreas transplantation is the definite treatment for type 1 diabetes that enables the achievement of long-term normoglycemia and insulin independence. However Post-Transplantation Pancreatitis (PTP) due to ischemia reperfusion (IR) injury and preservation is a major complication in pancreas transplantation. Owning the potential anti-inflammatory effect of Cisplatin (Cis) in liver IR injury, we have examined if Cis could attenuate PTP using a murine model. We found that Cis is able to prevent inflammatory response in PTP. Pretreatment of Cis in recipient mice reduce the impairments of the grafts and hyperamylasimea in the recipients. We documented that the protective mechanism of Cis in PTP involves improvement of microcirculation, reduction of the mononuclear cellular infiltration and apoptosis, suppression of inflammatory cytokine-cascade and inhibition of translocation of high-motility group box protein-1 (HMGB-1) from nucleus to cytoplasm. In short, our study demonstrated that pretreatment of Cis in recipients may reduce the onset of PTP in pancreas transplantation. \u00a9 Ivyspring International Publisher.",
        "keywords": [
            "Cisplatin",
            "High-motility group box protein-1",
            "Intravital fluorescence microscopy",
            "Ischemia reperfusion injury",
            "Pancreatitis"
        ],
        "venue": "International Journal of Biological Sciences",
        "year": 2012,
        "id": "wbAtNcmn"
    },
    "1qr0mg3b": {
        "authors": [
            {
                "name": "Yongping Yang",
                "org": "Beijing Institute of Infectious Diseases"
            },
            {
                "name": "Yinying Lu",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Chunping Wang",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Wenlin Bai",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Jianhui Qu",
                "org": "Beijing Institute of Infectious Diseases"
            },
            {
                "name": "Yan Chen",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Xiujuan Chang",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Linjing An",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Lin Zhou",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Zhen Zeng",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Min Lou",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Jiyun Lv",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            }
        ],
        "title": "Cryotherapy is associated with improved clinical outcomes of sorafenib for the treatment of advanced hepatocellular carcinoma",
        "abstract": "Sorafenib may prolong survival in patients with advanced hepatocellular carcinoma (HCC), but with limited efficacy. The present study aimed to assess the safety and efficacy of sorafenib combined with cryotherapy (cryoRx) for the treatment of advanced HCC. A total of 104 patients met the following criteria: advanced HCC without distant metastasis, presence of portal vein thrombosis, Child-Pugh class A or B and life expectancy of at least 12 weeks. All patients were randomly assigned to sorafenib and cryoRx (n=52) or sorafenib-alone (n=52) treatment groups. The primary end-point of the study was overall survival (OS). The secondary end-points included time to progression (TTP) and tolerability. Microvessel density (MVD) was assessed following immunostaining for CD34. In a median of 10.5 (4-26) months follow-up, the median OS was 12.5 months (95% CI 10.6-16.4) in the combination therapy vs. 8.6 months (7.3-10.4) in the sorafenib-alone (P=0.01) group. The median TTP was 9.5 months (8.4-13.5) in the combination therapy vs. 5.3 months (3.8-6.9) in the sorafenib alone (P=0.02) group. CryoRx was an independent factor associated with improved clinical outcomes of sorafenib for the treatment of advanced HCC. Patients with low intratumoral MVD receiving the combination therapy exhibited a significantly longer median TTP and OS compared to those receiving sorafenib. High intratumoral MVD was an independent predictor of poor responses to sorafenib for advanced HCC. Compared with previous reports of sorafenib-related adverse drug reactions (ADRs), cryoRx did not further increase the frequency and degree of sorafenib-related ADRs. In conclusion, compared to sorafenib alone, the addition of cryoRx to sorafenib significantly improves the clinical outcomes of sorafenib for the treatment of advanced HCC with acceptable tolerance and similar safety profiles as previously reported. High intratumoral MVD is predictive of poor responses to sorafenib in advanced HCC patients.",
        "keywords": [
            "Cryotherapy",
            "Efficacy",
            "Hepatocellular carcinoma",
            "Microvessel density",
            "Safety",
            "Sorafenib"
        ],
        "venue": "Experimental and Therapeutic Medicine",
        "year": 2012,
        "id": "1qr0mg3b"
    },
    "qFU3R6F3": {
        "authors": [
            {
                "name": "Hong Li",
                "org": ""
            },
            {
                "name": "Hai-Yang Xie",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Xiao-Wen Feng",
                "org": ""
            },
            {
                "name": "Wei-Lin Wang",
                "org": ""
            },
            {
                "name": "Ting-Bo Liang",
                "org": ""
            },
            {
                "name": "Min Zhang",
                "org": ""
            },
            {
                "name": "Shu-Sen Zheng",
                "org": ""
            }
        ],
        "title": "Copy number variation in CCL3L1 gene is associated with susceptibility to acute rejection in patients after liver transplantation",
        "abstract": "Copy number variation (CNV) in gene was a novel type of genetic diversity in human that affect the pathogenesis, progress, and prognosis of disease. The aim of this study was to determine the associations between CNV in CCL3L1 gene and the rejection risk in liver-transplant recipients. The 266 Han-Chinese patients and 135 volunteers were enrolled in this study. Genomic DNA and mRNA samples were obtained from the whole peripheral blood; a quantitative real-time PCR-based assay was carried out to determine the copy number of CCL3L1, and real-time PCR was carried out to calculate the CCL3L1/CCL3 mRNA ratio. The CNV distributions in patients and health controls had no significant differences. Copy number in acute rejection group (AR) shifted to higher number compared with non-acute rejection group (4.74\u00b11.87 vs. 3.88\u00b12.13, p=0.017). Moreover, patients with higher CCL3L1 copies (\u22653 copies) had a significantly higher rejection risk than patients lower copies CCL3L1 (OR=3.85, 95% CI, 1.14-13.04; p=0.021). No association was found between CNV and rejection grades. In conclusion, liver transplant recipients with high copy number of CCL3L1 gene had a significant higher risk of AR. CNV might be a novel genetic diversity that correlated with allograft rejection. \u00a9 2011 John Wiley & Sons A/S.",
        "keywords": [
            "Acute rejection",
            "CCL3L1",
            "Chemokine receptor 5",
            "Copy number variation",
            "Liver transplantation"
        ],
        "venue": "Clinical Transplantation",
        "year": 2012,
        "id": "qFU3R6F3"
    },
    "cbSTSrhl": {
        "authors": [
            {
                "name": "Jian Zhang",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Lelin Pan",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Luyan Chen",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Xiaowen Feng",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Shusen Zheng",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            }
        ],
        "title": "Non-classical MHC-\u0399 genes in chronic hepatitis B and hepatocellular carcinoma",
        "abstract": "The non-classical human leukocyte antigens (HLA)-E, HLA-G, and HLA-F have been shown to modulate immune responses. We examined whether non-classical HLA polymorphisms are associated with hepatitis B virus (HBV) infection and hepatocellular carcinoma (HCC). Fifteen Single-nucleotide polymorphisms (SNPs) in these non-classical class I alleles were investigated by ligase detection reaction. A fragment of 650 bp located in the 3' untranslated region of HLA-G was investigated. Four SNPs (rs17875380, rs41557518, rs114465251, and rs115492845) were associated with altered susceptibility to HBV or HCC, and HLA-F*01:04, HLA-G*01:05N, and HLA-E*01:01 were associated with hepatitis B or hepatitis B complicated with HCC. Six of 16 designated HLA-E, -G, and -F haplotypes were associated with risk of hepatitis B or HCC. Our study provides healthy reference and detailed analyses of non-classical HLA class \u0399 polymorphisms that provide insight into immune mechanisms involved in susceptibility to hepatitis B and HCC. \u00a9 2011 Springer-Verlag.",
        "keywords": [
            "3' Untranslated region",
            "Hepatitis B virus",
            "Hepatocellular carcinoma",
            "Major histocompatibility complex",
            "Single nucleotide polymorphism"
        ],
        "venue": "Immunogenetics",
        "year": 2012,
        "id": "cbSTSrhl"
    },
    "t0V5eDup": {
        "authors": [
            {
                "name": "Jian-Wen Jiang",
                "org": "The Key Lab of Combined Multi-organ Transplantation"
            },
            {
                "name": "Zhi-Gang Ren",
                "org": "The Key Lab of Combined Multi-organ Transplantation"
            },
            {
                "name": "Guang-Ying Cui",
                "org": "State Key Laboratory for Diagnosis and Treatment of Infectious Disease"
            },
            {
                "name": "Zhao Zhang",
                "org": "The Key Lab of Combined Multi-organ Transplantation"
            },
            {
                "name": "Hai-Yang Xie",
                "org": "The Key Lab of Combined Multi-organ Transplantation"
            },
            {
                "name": "Lin Zhou",
                "org": "The Key Lab of Combined Multi-organ Transplantation"
            }
        ],
        "title": "Chronic bile duct hyperplasia is a chronic graft dysfunction following liver transplantation",
        "abstract": "AIM: To investigate pathological types and influential factors of chronic graft dysfunction (CGD) following liver transplantation (LT) in rats. METHODS: The whole experiment was divided into three groups: (1) normal group (n = 12): normal BN rats without any drug or operation; (2) syngeneic transplant group (SGT of BN-BN, n = 12): both donors and recipients were BN rats; and (3) allogeneic transplant group (AGT of LEW-BN, n = 12): Donors were Lewis and recipients were BN rats. In the AGT group, all recipients were subcutaneously injected by Cyclosporin A after LT. Survival time was observed for 1 year. All the dying rats were sampled, biliary tract tissues were performed bacterial culture and liver tissues for histological study. Twenty-one day after LT, 8 rats were selected randomly in each group for sampling. Blood samples from caudal veins were collected for measurements of plasma endotoxin, cytokines and metabonomic analysis, and faeces were analyzed for intestinal microflora. RESULTS: During the surgery of LT, no complications of blood vessels or bile duct happened, and all rats in each group were still alive in the next 2 wk. The long term observation revealed that a total of 8 rats in the SGT and AGT groups died of hepatic graft diseases, 5 rats in which died of chronic bile duct hyperplasia. Compared to the SGT and normal groups, survival ratio of rats significantly decreased in the AGT group (P < 0.01). Moreover, liver necrosis, liver infection, and severe chronic bile duct hyperplasia were observed in the AGT group by H and E stain. On 21 d after LT, compared with the normal group (25.38 \u00b1 7.09 ng/L) and SGT group (33.12 \u00b1 10.26 ng/L), plasma endotoxin in the AGT group was remarkably increased (142.86 \u00b1 30.85 ng/L) (both P < 0.01). Plasma tumor necrosis factor-\u03b1 and interleukin-6 were also significantly elevated in the AGT group (593.6 \u00b1 171.67 pg/mL, 323.8 \u00b1 68.30 pg/mL) vs the normal (225.5 \u00b1 72.07 pg/mL, 114.6 \u00b1 36.67 pg/mL) and SGT groups (321.3 \u00b1 88.47 pg/mL, 205.2 \u00b1 53.06 pg/mL) (P < 0.01). Furthermore, Bacterial cultures of bile duct tissues revealed that the rats close to death from the SGT and AGT groups were strongly positive, while those from the normal group were negative. The analysis of intestinal microflora was performed. Compared to the normal group (7.98 \u00b1 0.92, 8.90 \u00b1 1.44) and SGT group (8.51 \u00b1 0.46, 9.43 \u00b1 0.69), the numbers of Enterococcus and Enterobacteria in the AGT group (8.76 \u00b1 1.93, 10.18 \u00b1 1.64) were significantly increased (both P < 0.01). Meanwhile, compared to the normal group (9.62 \u00b1 1.60, 9.93 \u00b1 1.10) and SGT group (8.95 \u00b1 0.04, 9.02 \u00b1 1.14), the numbers of Bifidobacterium and Lac-tobacillus in the AGT group (7.83 \u00b1 0.72, 8.87 \u00b1 0.13) were remarkably reduced (both P < 0.01). In addition, metabonomics analysis showed that metabolic profiles of plasma in rats in the AGT group were severe deviated from the normal and SGT groups. CONCLUSION: Chronic bile duct hyperplasia is a pathological type of CGD following LT in rats. The mechanism of this kind of CGD is associated with the alterations of inflammation, intestinal barrier function and microflora as well as plasma metabolic profiles. \u00a9 2012 Baishideng. All rights reserved.",
        "keywords": [
            "Chronic bile duct hyperplasia",
            "Chronic graft dysfunction",
            "Intestinal barrier function",
            "Liver transplantation",
            "Metabonomics"
        ],
        "venue": "World Journal of Gastroenterology",
        "year": 2012,
        "id": "t0V5eDup"
    },
    "nakqMasm": {
        "authors": [
            {
                "name": "Xiangyi He",
                "org": "Department of Gastroenterology"
            },
            {
                "name": "Zhong Zheng",
                "org": "Fudan University Shanghai Cancer Center"
            },
            {
                "name": "Jianfang Li",
                "org": "Key Laboratory of Shanghai Gastric Neoplasms"
            },
            {
                "name": "Qiwen Ben",
                "org": "Department of Gastroenterology"
            },
            {
                "name": "Jun Liu",
                "org": "Fudan University Shanghai Cancer Center"
            },
            {
                "name": "Jianian Zhang",
                "org": "Key Laboratory of Shanghai Gastric Neoplasms"
            },
            {
                "name": "Jun Ji",
                "org": "Key Laboratory of Shanghai Gastric Neoplasms"
            },
            {
                "name": "Beiqin Yu",
                "org": "Key Laboratory of Shanghai Gastric Neoplasms"
            },
            {
                "name": "Xuehua Chen",
                "org": "Key Laboratory of Shanghai Gastric Neoplasms"
            },
            {
                "name": "Liping Su",
                "org": "Key Laboratory of Shanghai Gastric Neoplasms"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Gastroenterology"
            },
            {
                "name": "Bingya Liu",
                "org": "Key Laboratory of Shanghai Gastric Neoplasms"
            },
            {
                "name": "Yaozong Yuan",
                "org": "Department of Gastroenterology"
            }
        ],
        "title": "DJ-1 promotes invasion and metastasis of pancreatic cancer cells by activating SRC/ERK/uPA",
        "abstract": "A major hallmark of pancreatic ductal adenocarcinoma (PDAC) is extensive local tumor invasion and early systemic dissemination. DJ-1 has been shown to prevent cell death via the Akt pathway, thereby playing an important role in cancer progression and Parkinson's disease development. Here, we investigated the role of DJ-1 in tumor invasion and metastasis of pancreatic cancer and showed that DJ-1 is upregulated in 68.5% of pancreatic cancer specimens, correlated with tumor stage and predictive of short overall survival. Knockdown of DJ-1 expression in two PDAC cell lines reduced cell migration and invasion potential in vitro and inhibited metastasis in vivo. Knockdown of DJ-1 led to cytoskeleton disruption and diminished urokinase plasminogen activator (uPA) activity and expression, without affecting plasminogen activator inhibitor-1 and uPA receptor (uPAR) expression. All these effects were reversed by restoration of DJ-1 expression. In determining the pathway through which DJ-1 regulated cell migration and invasion, DJ-1 was found not to regulate Akt phosphorylation. Rather, it promoted extracellular signal-regulated kinase (ERK) and SRC phosphorylation. Inhibition of the ERK pathway in PDAC mimicked the effects of DJ-1 on cell migration, invasion, actin cytoskeleton and uPA/uPAR system and abolished the effects on promoting PDAC cell invasion and migration. These data represent the first identification of an important function of DJ-1, which is to regulate the invasion and metastasis properties of PDAC through the ERK/uPA cascade. \u00a9 The Author 2012. Published by Oxford University Press. All rights reserved.",
        "keywords": [
            ""
        ],
        "venue": "Carcinogenesis",
        "year": 2012,
        "id": "nakqMasm"
    },
    "Gfn6CTkD": {
        "authors": [
            {
                "name": "Chunyang Xing",
                "org": "Key Lab of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Haiyang Xie",
                "org": "Key Lab of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Lab of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Wuhua Zhou",
                "org": "Key Lab of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Wu Zhang",
                "org": "Key Lab of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Songming Ding",
                "org": "Key Lab of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Bajin Wei",
                "org": "Key Lab of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Xiaobo Yu",
                "org": "Key Lab of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Rong Su",
                "org": "Key Lab of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Shusen Zheng",
                "org": "Key Lab of Combined Multi-Organ Transplantation"
            }
        ],
        "title": "Cyclin-dependent kinase inhibitor 3 is overexpressed in hepatocellular carcinoma and promotes tumor cell proliferation",
        "abstract": "Cyclin-dependent kinase inhibitor 3 (CDKN3) belongs to the protein phosphatases family and has a dual function in cell cycling. The function of this gene has been studied in several kinds of cancers, but its role in human hepatocellular carcinoma (HCC) remains to be elucidated. In this study, we found that CDKN3 was frequently overexpressed in both HCC cell lines and clinical samples, and this overexpression was correlated with poor tumor differentiation and advanced tumor stage. Functional studies showed that overexpression of CDKN3 could promote cell proliferation by stimulating G1-S transition but has no impact on cell apoptosis and invasion. Microarray-based co-expression analysis identified a total of 61 genes co-expressed with CDKN3, with most of them involved in cell proliferation, and BIRC5 was located at the center of CDKN3 co-expression network. These results suggest that CDKN3 acts as an oncogene in human hepatocellular carcinoma and antagonism of CDKN3 may be of interest for the treatment of HCC. \u00a9 2012 Elsevier Inc.",
        "keywords": [
            "BIRC5",
            "CDKN3",
            "Co-expression",
            "Oncomine",
            "P21"
        ],
        "venue": "Biochemical and Biophysical Research Communications",
        "year": 2012,
        "id": "Gfn6CTkD"
    },
    "58oH1c7o": {
        "authors": [
            {
                "name": "Jun-Hui Sun",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Yue-Lin Zhang",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Chun-Hui Nie",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Xiao-Bo Yu",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Hai-Yang Xie",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            }
        ],
        "title": "Considerations for two inoculation methods of rabbit hepatic tumors: Pathology and image features",
        "abstract": "The rabbit VX2 hepatic tumor model has been widely used for the investigation of liver cancer. The present study was designed to compare two inoculation methods in order to identify an improved modality for establishing rabbit hepatic tumors. A total of 44 rabbits were randomly divided into 2 groups. All inoculations were performed by open laparotomy. In group 1, 22 rabbits received a VX2 tumor cell suspension in a volume of 0.2 ml, which was slowly injected into the rabbit liver parenchyma using an 18-gauge needle. In group 2, a 0.2-ml suspension of small, minced tumor fragments of a VX2 carcinoma, inserted into an 18-gauge needle, was implanted into the liver parenchyma. The tumor survival ratio, size and extrahepatic metastases were evaluated and compared using computed tomography (CT)-scan, angiography and pathological specimens. At 2 weeks following implantation, successful liver tumor growth was achieved in 14 out of the 22 rabbits in group 1 (63.6%) and 21 out of the 22 rabbits in group 2 (95.5%) (P<0.05). Further sub-analysis revealed that single nodular tumors in the liver were observed in 4 out of the 14 rabbits in group 1 (28.6%) and 14 out of the 21 rabbits in group 2 (66.7%), and that multinodular tumors in the liver were observed in 10 out of the 14 rabbits in group 1 (71.4%) and 7 out of the 21 rabbits in group 2 (33.3%) (P<0.05). Extrahepatic metastases were observed in 5 out of the 14 rabbits in group 1 (35.7%) and 1 of the 21 rabbits in group 2 (4.8%) (P<0.05). Imaging findings of hepatic tumors were in concordance with histopathology. In conclusion, direct implantation of VX2 tumor fragments into the liver using a fine needle achieved a higher success rate than injecting VX2 tumor cells. The rabbit hepatic tumors inoculated by this method may therefore be a more suitable animal model for investigating liver cancer.",
        "keywords": [
            "Angiography",
            "Computed tomography",
            "Liver neoplasm",
            "Rabbit",
            "VX2 tumor"
        ],
        "venue": "Experimental and Therapeutic Medicine",
        "year": 2012,
        "id": "58oH1c7o"
    },
    "3GLEEH1m": {
        "authors": [
            {
                "name": "Zhenhua Hu",
                "org": "Department of Surgery"
            },
            {
                "name": "Zhiwei Li",
                "org": "Department of Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Surgery"
            },
            {
                "name": "Weilin Wang",
                "org": "Department of Surgery"
            },
            {
                "name": "Min Zhang",
                "org": "Department of Surgery"
            },
            {
                "name": "Yan Shen",
                "org": "Department of Surgery"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Department of Surgery"
            }
        ],
        "title": "Association of family history of HBV with resectability of hepatocellular carcinoma",
        "abstract": "Background/Aims: This study aims to address the relationship between a positive family history of liver cancer or hepatitis B virus (HBV) infection and the operative resectability of hepatocellular carcinoma (HCC) in the Chinese population. Methodology: Two hundred and sixty-two HCC patients underwent operative or non-operative therapies in our hospital. One hundred and eighteen of the patients were clinically considered as resectable patients. The remaining 144 patients were clinically unresectable. Statistical analysis was performed in SPSS 15.0 for Windows. Results: A family history of HBV infection is significantly associated with the resectability of HCC (AOR=2.332; 95% CI, 1.051-5.177). There was also has a significant association between the first degree relatives infected with HBV and the resectability of HCC (AOR=2.334; 95% CI, 1.050-5.190), especially a patient's sibling having a history of HBV infection is significantly related to the resectability of HCC (AOR=2.727; 95% CI, 1.092-6.808). Conclusions: A family history of HBV infection is associated with the resectability of HCC, and in particular, if a patient's sibling has a history of HBV infection, this indicates a reduced opportunity to receive curative liver resection. \u00a9 H.G.E. Update Medical Publishing S.A.",
        "keywords": [
            "First degree relatives",
            "HCC diagnosis",
            "Liver cancer",
            "Risk factors",
            "Surgical resection"
        ],
        "venue": "Hepato-Gastroenterology",
        "year": 2012,
        "id": "3GLEEH1m"
    },
    "9n6bh0Nm": {
        "authors": [
            {
                "name": "Weilin Wang",
                "org": "Key Lab of Organ Transplantation"
            },
            {
                "name": "Jianju Lu",
                "org": "Key Lab of Organ Transplantation"
            },
            {
                "name": "Feng Zhu",
                "org": "Key Lab of Organ Transplantation"
            },
            {
                "name": "Jianfeng Wei",
                "org": "Key Lab of Organ Transplantation"
            },
            {
                "name": "Changku Jia",
                "org": "Key Lab of Organ Transplantation"
            },
            {
                "name": "Yuanbiao Zhang",
                "org": "Key Lab of Organ Transplantation"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Lab of Organ Transplantation"
            },
            {
                "name": "Haiyang Xie",
                "org": "Key Lab of Organ Transplantation"
            },
            {
                "name": "Shusen Zheng",
                "org": "Key Lab of Organ Transplantation"
            }
        ],
        "title": "Pro-apoptotic and anti-proliferative effects of mitofusin-2 via Bax signaling in hepatocellular carcinoma cells",
        "abstract": "Mitochondrial GTPase mitofusin-2 (Mfn2) is a novel gene that remarkably suppresses the injury-mediated proliferation of vascular smooth muscle cells (VSMCs) and has a potential apoptotic effect via the mitochondrial apoptotic pathway. Hepatocellular carcinoma (HCC) tissues and matched normal tissues were examined for mfn2 expression. HCC cells were infected with adenovirus carrying Mfn2 (Ad-mfn2) or green fluorescent protein (Ad-GFP), used as a control. Short hairpin RNA (shRNA) was formed by shR-mfn2 and shR-Bax to repress mfn2 and Bax transcription, respectively. The effects of mfn2 on cell cycle distribution and apoptosis were measured by flow cytometric analysis. Significant downregulation of mfn2 was observed in HCC tissues compared with nearby normal tissues. Overexpression of mfn2 inhibited HCC cell proliferation and induced apoptosis by increasing the level of active caspase-3 and poly (ADP-ribose) polymerase (PARP) cleavage. Overexpression of mfn2 also induced cytochrome c release to the cytoplasm by enhancing Bax translocation from the cytoplasm to the mitochondrial membrane. Upregulation of mfn2 promoted apoptosis of HCC cells, and this was dramatically suppressed by shRBax. Our results show that the mfn2 gene is a potential tumor suppressor target that may significantly promote apoptosis via Bax and may inhibit proliferation in HCC cells. This gene may be an important therapeutic target for the treatment of tumors or hyperproliferative diseases. \u00a9 2011 Springer Science+Business Media, LLC.",
        "keywords": [
            "Apoptosis",
            "Bax",
            "Hepatocellular carcinoma",
            "Mfn2",
            "Mitochondria"
        ],
        "venue": "Medical Oncology",
        "year": 2012,
        "id": "9n6bh0Nm"
    },
    "07VPOymN": {
        "authors": [
            {
                "name": "Zhongchun Tong",
                "org": "Department of Operative Dentistry and Endodontics"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Stomatology"
            },
            {
                "name": "Rong Kuang",
                "org": "Department of Operative Dentistry and Endodontics"
            },
            {
                "name": "Haipeng Lv",
                "org": "Department of Operative Dentistry and Endodontics"
            },
            {
                "name": "Tiejun Qu",
                "org": "Department of Operative Dentistry and Endodontics"
            },
            {
                "name": "Longxing Ni",
                "org": "Department of Operative Dentistry and Endodontics"
            }
        ],
        "title": "In vitro evaluation of MTAD and nisin in combination against common pathogens associated with root canal infection",
        "abstract": "Introduction: Many pathogenic microorganisms were found in an infected root canal. The object of this study was to evaluate the effect of MTAD in combination with nisin on the pathogens associated with root canal infection. Methods: The survival rates of 9 pathogenic bacteria were determined after 1-, 5-, and 10-minute treatment with MTAD, MTAN (substitution of doxycycline with nisin), and MTADN (nisin in combination with doxycycline). The survival rates of Enterococcus faecalis in the starvation phase and pretreatment alkalization as well as in the normal physiological state under MTAD, MTAN, and MTADN challenge for 1, 5, and 10 minutes were evaluated and compared. Furthermore, scanning electron microscopy was used to observe the morphologic modification of Actinomyces naeslundii, Lactobacillus paracasei, and Porphyromonas gingivalis after MTAD and MTADN treatment. Results: L. fermenti, L. paracasei, A. viscosus, A. naeslundii, Streptococcus gordonii, and Peptostreptococcus were more sensitive to MTADN and MTAN than to MTAD. MTAD, MTAN, and MTADN showed a rapid antibacterial effect on P. gingivalis, Prevotella intermedia, and Fusobacterium nucleatum. Enterococcus faecalis in the stress state was as sensitive to MTAD, MTAN, and MTADN as the control E. faecalis. Furthermore, in the observation of scanning electron microscopy, the membranes in A. naeslundii and L. paracasei presented significant rupture, and P. gingivalis did not exhibit significant damage after MTADN treatment. Conclusions: MTAD in combination with nisin improved antibacterial efficacy against pathogens, especially for some gram-positive bacteria associated with persistent intracanal infection. Therefore, the combination had the potential to be used as an effective intracanal irrigation. \u00a9 2012 American Association of Endodontists.",
        "keywords": [
            "Enterococcus faecalis",
            "MTAD",
            "MTADN",
            "MTAN",
            "nisin"
        ],
        "venue": "Journal of Endodontics",
        "year": 2012,
        "id": "07VPOymN"
    },
    "WvHWhcKS": {
        "authors": [
            {
                "name": "Xiao Xu",
                "org": "Department of Surgery"
            },
            {
                "name": "Xuyong Wei",
                "org": "Department of Surgery"
            },
            {
                "name": "Qi Ling",
                "org": "Department of Surgery"
            },
            {
                "name": "Kai Wang",
                "org": "Department of Surgery"
            },
            {
                "name": "Haiwei Bao",
                "org": "Department of Surgery"
            },
            {
                "name": "Haiyang Xie",
                "org": "Department of Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Surgery"
            },
            {
                "name": "Shusen Zheng",
                "org": "Department of Surgery"
            }
        ],
        "title": "Inaccurate preoperative imaging assessment on biliary anatomy not increases biliary complications after living donor liver transplantation",
        "abstract": "Backgrounds and aims: Accurate assessment of graft bile duct is important to plan surgical procedure. Magnetic resonance cholangiopancreatography (MRCP) has become an important diagnostic procedure in evaluation of pancreaticobiliary ductal abnormalities and has been reported as highly accurate. We aim to estimate the efficacy of preoperative MRCP on depicting biliary anatomy in living donor liver transplantation (LDLT), and to determine whether inaccurate preoperative imaging assessment would increase the biliary complications after LDLT. Methods: The data of 118 cases LDLT were recorded. Information from preoperative MRCP was assessed using intraoperative cholangiography (IOC) as the gold standard. The possible risk factors of recipient biliary complications were analyzed. Results: Of 118 donors, 84 had normal anatomy (type A) and 34 had anatomic variants (19 cases of type B, 9 cases of type C, 1 case of type E, 2 cases of type F and 3 cases of type I) confirmed by IOC. MRCP correctly predicted all 84 normal cases and 17 of 34 variant cases, and showed an accuracy of 85.6% (101/118). The incidence of biliary complications was comparable between cases with accurate and inaccurate classification of biliary tree from MRCP, and between cases with normal and variant anatomy of bile duct. While cases with graft duct opening \u22645 mm showed a significant higher incidence of total biliary complications (21.1% vs. 6.6%, P = 0.028) and biliary stricture (10.5% vs. 1.6%, P = 0.041) compared with cases with large duct opening >5 mm. Conclusion: MRCP could correctly predict normal but not variant biliary anatomy. Inaccurate assessment of biliary anatomy from MRCP not increases the rate of biliary complications, while small-sized graft duct may cause an increase in biliary complications particularly biliary stricture after LDLT. \u00a9 2011 Elsevier Ireland Ltd. All rights reserved.",
        "keywords": [
            "Bil0069ary anatomy",
            "Biliary complications",
            "Living donor liver transplantation",
            "MRCP"
        ],
        "venue": "European Journal of Radiology",
        "year": 2012,
        "id": "WvHWhcKS"
    },
    "k6f3cUVY": {
        "authors": [
            {
                "name": "Zhongchun Tong",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Jie Li",
                "org": ""
            },
            {
                "name": "Rong Kuang",
                "org": ""
            },
            {
                "name": "Yuan Lin",
                "org": ""
            },
            {
                "name": "Longxing Ni",
                "org": ""
            }
        ],
        "title": "An in vitro investigation of Lactococcus lactis antagonizing cariogenic bacterium Streptococcus mutans",
        "abstract": "Objectives: The present study tested the antagonism between Lactococcus lactis and Streptococcus mutans and evaluated the feasibility of the application of L. lactis for the inhibition of S. mutans in the oral cavity. Methods: Competition assays on plates were employed to determine whether L. lactis antagonises S. mutans under different nutritional conditions, and real-time reverse-transcriptase PCR was used to evaluate the effects of metabolites of S. mutans on the bacteriocin nisin genes in L. lactis. Furthermore, the colonisation and effects of L. lactis on the surface of a tooth were examined by scanning electron microscopy. Results: L. lactis competitively inhibited S. mutans growth under nutritional deficiency, and the metabolites of S. mutans, including several exogenous molecular signals, enhanced the expression of genes related to nisin synthesis, nisA, nisB and nisI. Additionally, L. lactis effectively colonised the surface of tooth enamel, which showed substantially less decay with L. lactis adhesion compared to S. mutans adhesion. Conclusions: These findings suggest avenues of research into a new strategy to reduce major cariogenic S. mutans adhesion on the surfaces of teeth. \u00a9 2011 Elsevier Ltd. All rights reserved.",
        "keywords": [
            "Antagonism",
            "Lactococcus lactis",
            "Nisin",
            "Streptococcus mutans"
        ],
        "venue": "Archives of Oral Biology",
        "year": 2012,
        "id": "k6f3cUVY"
    },
    "rbNMgcNX": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Engineering Research Center of Bio-process"
            },
            {
                "name": "Chang-Sheng Gan",
                "org": "Engineering Research Center of Bio-process"
            },
            {
                "name": "Hao-Shu Wang",
                "org": "Engineering Research Center of Bio-process"
            },
            {
                "name": "Zhen-Zhen Zhao",
                "org": "Engineering Research Center of Bio-process"
            },
            {
                "name": "Jian Pan",
                "org": "Engineering Research Center of Bio-process"
            }
        ],
        "title": "Synthesis of benzothiazole derivatives and their binding characteristics with \u03b2-amyloid",
        "abstract": "Alzheimer's disease (AD) is a progressive neurodegenerative disease endangering human health seriously. Recent reports have revealed that \u03b2-amyloid aggregates play a key role in the pathogenesis of AD. Thus, targeting the A\u03b2 plaques benzothiazole derivatives were synthesized with the scaffold of the most promising imaging agent PIB ([",
        "keywords": [
            "\u03b2-amyloid",
            "Alzheimer's disease",
            "PIB",
            "Schiff base",
            "Surface plasmon resonance"
        ],
        "venue": "Yaoxue Xuebao",
        "year": 2012,
        "id": "rbNMgcNX"
    },
    "y24ePQ83": {
        "authors": [
            {
                "name": "Xiao-Yue Fu",
                "org": "Department of Thoracic Oncology"
            },
            {
                "name": "J. Ian Xin Xue",
                "org": "Department of Thoracic Oncology"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Thoracic Oncology"
            },
            {
                "name": "Yong-Sheng Wang",
                "org": "Department of Thoracic Oncology"
            },
            {
                "name": "Mei-Juan Huang",
                "org": "Department of Thoracic Oncology"
            },
            {
                "name": "Lu Li",
                "org": "Department of Thoracic Oncology"
            },
            {
                "name": "You Lu",
                "org": "State Key Laboratory of Biotherapy"
            }
        ],
        "title": "The protection effects of resveratrol on irradiated human pneumonic cell lines and its mechanism",
        "abstract": "Objective This study was to explore whether resveratrol could protect human bronchial epithelial cells (HBE) and human fetal lung fibroblasts (MRC5) from radiation injury and to investigate its potential mechanism. Methods HBE and MRC5 were divided into four groups. Group 1 (Vehicle), control group, only treated with vehicle; Group 2 (resveratrol, Res), the resveratrol group, treated with 5 \u03bcmol/L resveratrol; Group 3 (RT+Vehicle), the X-ray irradiation group, only subjected to irradiation of 20 Gy X-ray; Group 4 (RT+Res), the combination therapy group, 2 hours before X-ray treatment (20 Gy, 8. 33 Gy/min for 144 s), 5 \u03bcmol/L resveratrol was added to the cells. Several experimental methods were used to observe cellular morphology, ultrastructure, viability, DNA damage, apoptosis, and to determine the change of oxidative stress indexes such as reactive oxygen species (ROS), malondialdehyde (MDA), total glutathione (GSH) and superoxide dismutase (SOD). Results X-ray could induce HBE and MRC5 cell injury. Resveratrol could significantly ease the morphological and ultrastructure injury, relieve the decrease of cellular viability and the damage of DNA, and reduce cellular apoptosis. Besides, oxidative stress indexes including ROS, MDA, GSH, SOD were improved by resveratrol after irradiation. Conclusion Resveratrol protect HBE and MRC5 from radiation injury, which is related to the alleviation of oxidative stress injury.",
        "keywords": [
            "Human bronchial epithelial cells",
            "Human fetal lung fibroblasts",
            "Oxidative stress injury",
            "Radiation injury resveratrol"
        ],
        "venue": "Journal of Sichuan University (Medical Science Edition)",
        "year": 2012,
        "id": "y24ePQ83"
    },
    "vKxqgyi2": {
        "authors": [
            {
                "name": "Zhenhua Hu",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Jie Zhou",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Xiaofeng Xu",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Zhiwei Li",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Jian Wu",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Min Zhang",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Shusen Zheng",
                "org": "Key Laboratory of Organ Transplantation"
            }
        ],
        "title": "Salvage liver transplantation is a reasonable option for selected patients who have recurrent hepatocellular carcinoma after liver resection",
        "keywords": [
            ""
        ],
        "venue": "PLoS ONE",
        "year": 2012,
        "id": "vKxqgyi2"
    },
    "T4ibVwdS": {
        "authors": [
            {
                "name": "Weilin Wang",
                "org": "Key Lab of Organ Transplantation, Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Dongkai Zhou",
                "org": "Key Lab of Organ Transplantation, Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Jianfeng Wei",
                "org": "Key Lab of Organ Transplantation, Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Zehui Wu",
                "org": "Key Lab of Organ Transplantation, Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Xiaofei Cheng",
                "org": "Department of Anorectal Surgery"
            },
            {
                "name": "Qiang Sun",
                "org": "Key Lab of Organ Transplantation, Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Haiyang Xie",
                "org": "Key Lab of Organ Transplantation, Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Lab of Organ Transplantation, Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Shusen Zheng",
                "org": "Key Lab of Organ Transplantation, Department of Hepatobiliary and Pancreatic Surgery"
            }
        ],
        "title": "Hepatitis B virus X protein inhibits p53-mediated upregulation of mitofusin-2 in hepatocellular carcinoma cells",
        "abstract": "The hepatitis B virus X (HBx) protein has many significant roles in hepatocellular carcinoma (HCC). Our previous research demonstrated that mitofusion-2 (Mfn2), a potential tumor suppressor gene in HCC, is a novel direct target of p53 that exerts apoptotic effects via the mitochondrial apoptotic pathway. However, the relationship between HBx and Mfn2 expression in the development of HCC is unknown. We found that HBx had little direct effect on the expression of Mfn2 or p53 in HCC cells not treated with doxorubicin. However, HBx inhibited the upregulation of Mfn2 in HBx-transfected HCC cells simultaneously treated with doxorubicin or cotransfected with p53 plasmid, as evidenced by Western Blot and real-time PCR. Through electrophoretic mobility shift analysis, we confirmed that HBx interfered with the binding event of the p53 protein and the p53 binding site-oligo of the Mfn2 promoter. Moreover, luciferase assays revealed that the activity of the Mfn2 promoter did not increase when transfected with HBx plasmid in doxorubicin-treated HepG2 cells. These results indicate that HBx impacts p53-mediated transcription of Mfn2, providing insight into the negative effect of HBx against p53-dependent chemotherapeutic agents, such as doxorubicin, used in the treatment of HCC. \u00a9 2012 Elsevier Inc.",
        "keywords": [
            "Doxorubicin",
            "Hepatitis B virus X protein",
            "Hepatocellular carcinoma",
            "Mitofusin-2",
            "P53"
        ],
        "venue": "Biochemical and Biophysical Research Communications",
        "year": 2012,
        "id": "T4ibVwdS"
    },
    "VXEPPMkW": {
        "authors": [
            {
                "name": "Qianqian Zhu",
                "org": "Department of Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Surgery"
            },
            {
                "name": "Zhe Yang",
                "org": "Department of Surgery"
            },
            {
                "name": "Mingchun Lai",
                "org": "Department of Surgery"
            },
            {
                "name": "Haiyang Xie",
                "org": "Department of Surgery"
            },
            {
                "name": "Liming Wu",
                "org": "Department of Surgery"
            },
            {
                "name": "Chunyang Xing",
                "org": "Department of Surgery"
            },
            {
                "name": "Feng Zhang",
                "org": "Department of Surgery"
            },
            {
                "name": "Shusen Zheng",
                "org": "Department of Surgery"
            }
        ],
        "title": "O-GlcNAcylation plays a role in tumor recurrence of hepatocellular carcinoma following liver transplantation",
        "abstract": "O-linked-\u00df-N-acetylglucosamine (O-GlcNAc) modification is a crucial post-translational modification. The enzymes responsible for the addition and removal of O-GlcNAc have been identified as O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA). In this study, O-GlcNAcylation level was examined in forty hepatocellular carcinoma (HCC) tissues of patients who underwent liver transplantation (LT) and ten healthy liver tissues by immunohistochemistry analysis. We also examined the expression of OGT and OGA in sixty HCC samples using real-time reverse-transcription polymerase chain reaction and analyzed their correlations with clinical parameters and prognosis in sixty HCC patients treated with LT. Additionally, the global O-GlcNAcylation level was altered through OGT and OGA silencing in the HCC cell line, and the effects of O-GlcNAcylation on cancer malignancy were investigated. We found that the global O-GlcNAcylation levels were significantly elevated in HCC tissues than that in healthy liver tissues (P = 0.031); moreover, O-GlcNA cylation was significantly enhanced in the tumor tissues of patients who had suffered from HCC recurrence after LT compared with those who had not (P = 0.046). Importantly, low expression of OGA was an independent prognostic factor for predicting tumor recurrence of HCC following LT (P = 0.041, hazard ratio, 0.438), especially in AFP low patients. In vitro assays demonstrated that O-GlcNAcylation play important roles in migration, invasion, and viability of HCC cells, partly through regulating E-cadherin, MMP1, MMP2, and MMP3 expression. Altogether, these results suggest that O-GlcNAcylation might play important roles in HCC formation and progression and may be a potential marker to predict patient risk of recurrence after LT and a valuable target for therapy. \u00a9 Springer Science+Business Media, LLC 2011.",
        "keywords": [
            "E-cadherin",
            "Hepatocellular carcinoma (HCC)",
            "Liver transplantation (LT)",
            "O-GlcNAc",
            "O-GlcNAcase (OGA)",
            "Recurrence"
        ],
        "venue": "Medical Oncology",
        "year": 2012,
        "id": "VXEPPMkW"
    },
    "6cgZnwIv": {
        "authors": [
            {
                "name": "Jian-Hui Qu",
                "org": "Center of Therapeutic Research for Liver Cancer"
            },
            {
                "name": "Xiu-Juan Chang",
                "org": "Center of Therapeutic Research for Liver Cancer"
            },
            {
                "name": "Yin-Ying Lu",
                "org": "Center of Therapeutic Research for Liver Cancer"
            },
            {
                "name": "Wen-Lin Bai",
                "org": "Center of Therapeutic Research for Liver Cancer"
            },
            {
                "name": "Yan Chen",
                "org": "Center of Therapeutic Research for Liver Cancer"
            },
            {
                "name": "Lin Zhou",
                "org": "Center of Therapeutic Research for Liver Cancer"
            },
            {
                "name": "Zhen Zeng",
                "org": "Center of Therapeutic Research for Liver Cancer"
            },
            {
                "name": "Chun-Ping Wang",
                "org": "Center of Therapeutic Research for Liver Cancer"
            },
            {
                "name": "Lin-Jing An",
                "org": "Center of Therapeutic Research for Liver Cancer"
            },
            {
                "name": "Li-Yan Hao",
                "org": "Center of Therapeutic Research for Liver Cancer"
            },
            {
                "name": "Gui-Lin Xu",
                "org": "Center of Therapeutic Research for Liver Cancer"
            },
            {
                "name": "Xu-Dong Gao",
                "org": "Center of Therapeutic Research for Liver Cancer"
            },
            {
                "name": "Min Lou",
                "org": "Center of Therapeutic Research for Liver Cancer"
            },
            {
                "name": "Ji-Yun Lv",
                "org": "Institute for Infectious Disease"
            },
            {
                "name": "Yong-Ping Yang",
                "org": "Institute for Infectious Disease"
            }
        ],
        "title": "Overexpression of metastasis-associated in colon cancer 1 predicts a poor outcome of hepatitis B virus-related hepatocellular carcinoma",
        "abstract": "AIM: To investigate the intratumoral expression of metastasis-associated in colon cancer 1 (MACC1) and c-Met and determine their clinical values associated with hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC). METHODS: A retrospective study admitted three hundred fifty-four patients with HBV-related HCC. The expression and distribution of MACC1 and c-Met were assessed by quantitative real-time polymerase chain reaction and immunohistochemistry staining. Prognostic factors influencing survival, metastasis and recurrence were assessed. RESULTS: Intratumoral MACC1 level was found to be associated with HCC disease progression. Both median tumor-free survival (TFS) and overall survival (OS) were significantly shorter in the postoperative HCC patients with high intratumoral MACC1 expression, as compared to those with low intratumoral MACC1 levels (TFS: 34 mo vs 48.0 mo, P < 0.001; OS: 40 mo vs 48 mo, P < 0.01). Multivariable analysis indicated that high MACC1 expression or co-expression with c-Met were independent predictors for HCC clinic outcome (P < 0.001). CONCLUSION: High intratumoral MACC1 expression can be associated with enhanced tumor progression and poor outcome of HBV-related HCC. MACC1 mayserve as a prognostic biomarker for postoperative HCC. \u00a9 2012 Baishideng. All rights reserved.",
        "keywords": [
            "c-met",
            "Hepatocellular carcinoma",
            "Metastasis-associated in colon cancer 1",
            "Prognostic factor",
            "Recurrence"
        ],
        "venue": "World Journal of Gastroenterology",
        "year": 2012,
        "id": "6cgZnwIv"
    },
    "bU48Hzlw": {
        "authors": [
            {
                "name": "Lelin Pan",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Wenjin Zhang",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Jian Zhang",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Lanjuan Li",
                "org": "Department of Infectious Diseases"
            },
            {
                "name": "Shusen Zheng",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            }
        ],
        "title": "The analysis of CD45 isoforms expression on HBV-specific T cells after liver transplantation",
        "abstract": "This study aimed to analyze the expression of CD45 on HBV-specific T cells in patients who underwent liver transplantation (LT). We detected the distribution of two CD45 isoforms (CD45RA, CD45RO) and CD27 on peripheral blood lymphocytes including two HBV-specific pentamer cells by flow cytometry. Meanwhile, the levels of tacrolimus, plasma IL-7, and IL-15 were tested by ELISA. CD45RA decreased sharply after LT, whereas the expression of CD45RO ",
        "keywords": [
            "CD27",
            "CD45",
            "Hepatitis B virus",
            "IL-7",
            "Liver transplantation"
        ],
        "venue": "Medical Oncology",
        "year": 2012,
        "id": "bU48Hzlw"
    },
    "rZR0m2wj": {
        "authors": [
            {
                "name": "Hefei Huang",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Hongmei Ren",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Caiyu Chen",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Xiaoyan Wang",
                "org": "Center for Molecular Physiology Research"
            },
            {
                "name": "Jian Yang",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Yu Han",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Duofen He",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Lin Zhou",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Laureano D. Asico",
                "org": "Center for Molecular Physiology Research"
            },
            {
                "name": "Pedro A. Jose",
                "org": "Center for Molecular Physiology Research"
            },
            {
                "name": "Chunyu Zeng",
                "org": "Chongqing Institute of Cardiology"
            }
        ],
        "title": "D ",
        "abstract": "Dopamine receptor, via D ",
        "keywords": [
            "kidney",
            "rats, normotensive",
            "rats, spontaneously hypertensive",
            "receptor, dopamine"
        ],
        "venue": "Hypertension Research",
        "year": 2012,
        "id": "rZR0m2wj"
    },
    "kkFtfE5I": {
        "authors": [
            {
                "name": "Jian Yang",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Caiyu Chen",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Hongmei Ren",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Yu Han",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Duofen He",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Lin Zhou",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Ulrich Hopfer",
                "org": "Department of Physiology and Biophysics"
            },
            {
                "name": "Pedro A. Jose",
                "org": "Department of Medicine"
            },
            {
                "name": "Chunyu Zeng",
                "org": "Chongqing Institute of Cardiology"
            }
        ],
        "title": "Angiotensin II AT ",
        "abstract": "Background: The renin-angiotensin (Ang) system controls blood pressure, in part, by regulating renal tubular sodium transport. In the kidney, activation of the angiotensin II type 1 (AT ",
        "keywords": [
            "AT 1 receptor",
            "AT 2 receptor",
            "hypertension",
            "renal proximal tubule cells"
        ],
        "venue": "Journal of Hypertension",
        "year": 2012,
        "id": "kkFtfE5I"
    },
    "EIuOdXUJ": {
        "authors": [
            {
                "name": "Yongping Yang",
                "org": "Infectious Diseases Institution of Beijing"
            },
            {
                "name": "Yinying Lu",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Chunping Wang",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Wenlin Bai",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Jianhui Qu",
                "org": "Infectious Diseases Institution of Beijing"
            },
            {
                "name": "Yan Chen",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Xiujuan Chang",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Linjing An",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Lin Zhou",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Zhen Zeng",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Min Lou",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Jiyun Lv",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            }
        ],
        "title": "Cryotherapy is Associated with Improved Clinical Outcomes of Sorafenib Therapy for Advanced Hepatocellular Carcinoma",
        "abstract": "We assessed the safety and efficacy of sorafenib with cryotherapy (cryoRx) in advanced hepatocellular carcinoma (HCC). One hundred four HCC patients were enrolled, who met the following criteria: (i) Barcelona Clinic Liver Cancer stage C; (ii) HCC without distant metastasis; (iii) the presence of portal vein thrombosis (PVT); (iv) Child-Pugh class A or B; and (v) life expectancy of at least 12 weeks. The patients were randomly divided into sorafenib-cryoRx and sorafenib (control) groups. Primary endpoint was time to progression (TTP); secondary endpoints included overall survival (OS) and tolerability. Microvessel density (MVD) was assessed by CD34-immunostaining. After a median 10.5 (4-26) months follow-up, the data showed that median TTP was 9.5 (8.4-13.5) months in combinatorial therapy group vs. 5.3 (3.8-6.9) months in sorafenib group (P = 0.02). The median OS was 12.5 (95 % CI 10.6-16.4) months in combination therapy group vs. 8.6 (7.3-10.4) months in sorafenib group (P = 0.01). Low MVD patients in combination therapy exhibited significantly longer median TTP and OS than controls. High MVD was predictive of poor responses to sorafenib. CryoRx did not increase frequency/degree of sorafenib-related adverse events. Therefore, it was concluded that the addition of cryoRx significantly improved clinical outcomes of Sorafenib therapy in advanced HCC with acceptable tolerance and similar safety profiles as previously reported. \u00a9 2012 The Author(s).",
        "keywords": [
            "Cryotherapy",
            "Efficacy",
            "Hepatocellular carcinoma",
            "Microvessel density",
            "Safety",
            "Sorafenib"
        ],
        "venue": "Cell Biochemistry and Biophysics",
        "year": 2012,
        "id": "EIuOdXUJ"
    },
    "Cb2ZuBpv": {
        "authors": [
            {
                "name": "Jian Zhang",
                "org": "State Key Laboratory of Biotherapy"
            },
            {
                "name": "Feng Peng",
                "org": "State Key Laboratory of Biotherapy"
            },
            {
                "name": "Na Li",
                "org": "Department of Oncology"
            },
            {
                "name": "Yongmei Liu",
                "org": "Department of Thoracic Oncology and Radiation Oncology"
            },
            {
                "name": "Yong Xu",
                "org": "Department of Thoracic Oncology and Radiation Oncology"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Biotherapy"
            },
            {
                "name": "Jin Wang",
                "org": "Department of Thoracic Oncology and Radiation Oncology"
            },
            {
                "name": "Jiang Zhu",
                "org": "Department of Thoracic Oncology and Radiation Oncology"
            },
            {
                "name": "Meijuan Huang",
                "org": "State Key Laboratory of Biotherapy"
            },
            {
                "name": "Youling Gong",
                "org": "State Key Laboratory of Biotherapy"
            }
        ],
        "title": "Salvage concurrent radio-chemotherapy for post-operative local recurrence of squamous-cell esophageal cancer",
        "abstract": "Purpose: To evaluate the treatment outcome of salvage concurrent radio-chemotherapy for patients with loco-recurrent esophageal cancer after surgery.Methods: 50 patients with loco-recurrent squamous-cell cancer after curative esophagectomy were retrospectively analyzed. Patients were treated with radiotherapy (median 60 Gy) combined with chemotherapy consisting of either 5-fluorouracil (5-FU) plus cisplatin (DDP) (R-FP group) or paclitaxel plus DDP (R-TP group).Results: The median follow-up period was 16.0 months. The 1-year and 3-year survival rates were 56% and 14%, respectively. The median progression-free survival (PFS) and overall survival (OS) time was 9.8 and 13.3 months respectively. There was no statistical significance of the PFS of the two groups. The OS (median 16.3 months) in the R-TP group was superior to that in the R-FP group (median: 9.8 months) (p = 0.012). Among the patients who had received \u226560 Gy irradiation dose, the median PFS (10.6 months) and OS (16.3 months) were significantly superior to the PFS (8.7 months) and OS (11.3 months) among those patients did not (all p < 0.05). Grade 3 treatment-related gastritis were observed in 6 (27.3%) and 7 (25%) patients in the R-FP and R-TP group respectively. By univariate survival analysis, the age (<60 years), TP regimen and higher irradiation dose might improve the OS of such patients in present study.Conclusions: For those patients with post-operative loco-recurrent squamous-cell esophageal carcinoma, radiotherapy combined with either FP or TP regimen chemotherapy was an effective salvage treatment. Younger age, treatment with the TP regimen and an irradiation dose \u226560 Gy might improve the patients' treatment outcome. \u00a9 2012 Zhang et al.; licensee BioMed Central Ltd.",
        "keywords": [
            "Post-operative local recurrence",
            "Salvage radio-chemotherapy",
            "Squamous-cell esophageal cancer",
            "Toxicity",
            "Treatment outcomes"
        ],
        "venue": "Radiation Oncology",
        "year": 2012,
        "id": "Cb2ZuBpv"
    },
    "xPwuCSyr": {
        "authors": [
            {
                "name": "Cheng Quan",
                "org": "Department of Dermatology"
            },
            {
                "name": "Zhi-Ping Wei",
                "org": "Department of Dermatology"
            },
            {
                "name": "Yan-Qun Liu",
                "org": "Department of Dermatology"
            },
            {
                "name": "Xin Jin",
                "org": "Department of Dermatology"
            },
            {
                "name": "Lian-Sheng Zhong",
                "org": "Department of Dermatology"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Dermatology"
            },
            {
                "name": "Xin-Bo Zhang",
                "org": "Department of Dermatology"
            },
            {
                "name": "Xing-Hong Zhang",
                "org": "Department of Dermatology"
            }
        ],
        "title": "Reflectance confocal microscopy image features of lichen planus",
        "abstract": "Objective: To investigate reflectance confocal microscopy (RCM) image features of lichen planus (LP). Methods: Five LP patients were examined by RCM, and then compared with histopathological examination. Results: All the lesions showed numerous, round bright inflammatory cells filling the papillary dermis and the ring feature of dermoepidermal junction was destructed (liquefaction degeneration of basal cells). The lesions of 4 patients showed focal wedge-shaped hypergranulosis and irregular acanthosis. Conclusion: RCM provides useful information and auxiliary technique for the diagnosis of LP.",
        "keywords": [
            "Lichen planus",
            "Reflectance confocal microscopy"
        ],
        "venue": "Journal of Clinical Dermatology",
        "year": 2012,
        "id": "xPwuCSyr"
    },
    "2YnnJIbv": {
        "authors": [
            {
                "name": "De-Juan Wang",
                "org": "Key Laboratory of Medical Neurobiology of the Ministry of Health"
            },
            {
                "name": "Dong Yang",
                "org": "Key Laboratory of Medical Neurobiology of the Ministry of Health"
            },
            {
                "name": "Li-Da Su",
                "org": "Neuroscience Care Unit"
            },
            {
                "name": "Ya-jun Xie",
                "org": "Key Laboratory of Medical Neurobiology of the Ministry of Health"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Medical Neurobiology of the Ministry of Health"
            },
            {
                "name": "Cheng-Long Sun",
                "org": "Key Laboratory of Medical Neurobiology of the Ministry of Health"
            },
            {
                "name": "Yin Wang",
                "org": "Department of Neurobiology, Center of Scientific Technology"
            },
            {
                "name": "Xin-Xin Wang",
                "org": "Key Laboratory of Medical Neurobiology of the Ministry of Health"
            },
            {
                "name": "Liang Zhou",
                "org": "Key Laboratory of Medical Neurobiology of the Ministry of Health"
            },
            {
                "name": "Ying Shen",
                "org": "Key Laboratory of Medical Neurobiology of the Ministry of Health"
            }
        ],
        "title": "Cytosolic phospholipase A 2 alpha/arachidonic acid signaling mediates depolarization-induced suppression of excitation in the cerebellum",
        "keywords": [
            ""
        ],
        "venue": "PLoS ONE",
        "year": 2012,
        "id": "2YnnJIbv"
    },
    "IUhmL2Wa": {
        "authors": [
            {
                "name": "Chunping Wang",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Yinying Lu",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Hong Wang",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Xudong Gao",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Wenlin Bai",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Jianhui Qu",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Guilin Xu",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Zhenzhen Zhang",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Zhen Zeng",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Lin Zhou",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Linjing An",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Jiyun Lv",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Yongping Yang",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            }
        ],
        "title": "Transarterial chemoembolization with/without cryotherapy is associated with improved clinical outcomes of sorafenib for the treatment of advanced hepatocellular carcinoma",
        "abstract": "Sorafenib may prolong survival in patients with advanced hepatocellular carcinoma (HCC), but with limited efficacy. The present study aimed to prospectively investigate the efficacy and analyze the prognostic factors for survival in sorafenib-treated patients with advanced HCC. The baseline characteristics and clinical outcomes of 110 patients with advanced hepatitis B virus-related HCC treated with sorafenib with/without local therapy (transarterial chemoembolization with/without cryoablation) at a single liver cancer center were recorded. Predictors of progression-free survival (PFS) and overall survival (OS) were determined by multivariate analysis. A total of 14 (12.7%) patients achieved complete response (CR), 16 (14.5%) achieved partial response (PR) and 40 (36.4%) achieved stable disease (SD) lasting longer than 8 weeks. The median OS and PFS for the whole cohort were 10.5 [95% confidence interval (CI), 8.7-12.3] and 5.0 months (95% CI, 3.7-6.3), respectively. Sorafenib in combination with local therapy was an independent predictor for longer PFS, whereas Eastern Cooperative Group (ECOG) performance status (PS) and Child-Pugh class were associated with reduced PFS. Local therapy was associated with longer OS while ECOG PS and \u03b1-fetoprotein were associated with reduced OS. In a subset of patients with radiological progressive disease, a significant difference was found in OS between patients who continued taking sorafenib and those who discontinued therapy (11 vs. 7.5 months, P<0.001). In conclusion, sorafenib in combination with local therapy (transarterial chemoembolization with/without cryoablation) was independently associated with longer OS and PFS in advanced HCC patients. Poor ECOG PS was associated with shorter OS and PFS and is thus a marker of poor outcomes in sorafenib-treated HCC patients.",
        "keywords": [
            "Cryoablation",
            "Hepatocellular carcinoma",
            "Prognostic factors",
            "Sorafenib",
            "Transarterial chemoembolization"
        ],
        "venue": "Experimental and Therapeutic Medicine",
        "year": 2012,
        "id": "IUhmL2Wa"
    },
    "7lA8NI0V": {
        "authors": [
            {
                "name": "Jun-Hui Sun",
                "org": "Department of Surgery"
            },
            {
                "name": "Yue-Lin Zhang",
                "org": "Department of Surgery"
            },
            {
                "name": "Chun-Hui Nie",
                "org": "Department of Surgery"
            },
            {
                "name": "Su-Ping Qian",
                "org": "Molecular Imaging Platform"
            },
            {
                "name": "Xiao-Bo Yu",
                "org": "Department of Surgery"
            },
            {
                "name": "Hai-Yang Xie",
                "org": "Department of Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Surgery"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Department of Surgery"
            }
        ],
        "title": "In vitro labeling of endothelial progenitor cells isolated from peripheral blood with superparamagnetic iron oxide nanoparticles",
        "abstract": "The transplantation of endothelial progenitor cells (EPCs) provides a novel method for the treatment of human tumors or vascular diseases. Magnetic resonance imaging (MRI) has proven to be effective in tracking transplanted stem cells by labeling the cells with superparamagnetic iron oxide (SPIO) nanoparticles. The SPIO has been used to label and track the EPCs; however, the effect of SPIO upon EPCs remains unclear on a cellular level. In the present study, EPCs were labeled with home-synthesized SPIO nanoparticles in vitro and the biological characteristics of the labeled EPCs were evaluated. The EPCs were isolated from the peripheral blood of New Zealand rabbits and cultured in fibronectin-coated culture flasks. The EPCs were labeled with home-synthesized SPIO nanoparticles at a final iron concentration of 20 \u03bcg/ml. Labeled EPCs were confirmed with transmission electron microscopy and P russian blue s taining. T he q uantity of i ron/cell was detected by atomic absorption spectrometry. The membranous antigens of EPCs were detected by cytofluorimetric analysis. Cell viability and proliferative capability between the labeled and unlabeled EPCs were compared. The rabbit EPCs were effectively labeled and the labeling efficiency was approximately 95%. The SPIO nanoparticles were localized in the endosomal vesicles of the EPCs, which were confirmed by transmission electron microscopy. No significant differences were found in cell viability and proliferative capability between labeled and unlabeled EPCs (P>0.05). In conclusion, rabbit peripheral blood EPCs were effectively labeled by home-synthesized SPIO nanoparticles, without influencing their main biological characteristics.",
        "keywords": [
            "Cell labeling",
            "Endothelial progenitor cell",
            "Superparamagnetic iron oxide nanoparticles"
        ],
        "venue": "Molecular Medicine Reports",
        "year": 2012,
        "id": "7lA8NI0V"
    },
    "bXN8PnTv": {
        "authors": [
            {
                "name": "Wen-Jin Zhang",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Hai-Yang Xie",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Xin Duan",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Yun-Le Wan",
                "org": "Department of Hepatobiliary Surgery"
            },
            {
                "name": "Chuan-Hui Peng",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Shao-Hua Shi",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Rong Su",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Zhang-Hui Zheng",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Le-Lin Pan",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            }
        ],
        "title": "Study of human B7 homolog 1 expression in patients with hepatitis B virus infection",
        "abstract": "AIM: To further investigate the role of human B7 homolog 1 (B7-H1) in the mechanism of persistent hepatitis B virus (HBV) infection. METHODS: Peripheral and intra-hepatic B7-H1 expression were compared by flow cytometry and immunochemical staining between two 2 distinct groups, one being chronic HBV tolerance patients (CHB-T) and the other being acute hepatitis B patients (AHB). B7-H1 mRNA expression level was also compared by real time polymerase chain reaction between CHB-T and AHB patients. The location of intra-hepatic B7-H1 and CD40 expression were analyzed by immunofluorescence. The levels of B7-H1 and CD40 expression on cultured myeloid dendritic cells (mDCs) with or without hepatitis B surface antigen (HBsAg) treatment were analyzed dynamically by flow cytometry. Intracellular interferon-\u03b3 (IFN-\u03b3) staining and the stimulatory capacity of mDC of cultured mDC with or without HBsAg treatment were also compared by flow cytometry. RESULTS: Peripheral B7-H1 expression on mDCs was increased significantly in AHB compared to CHB-T patients (P < 0.05). In the liver tissues from CHB-T patients, B7-H1 positive cells were almost absent despite a persistently elevated serum HBsAg load. In contrast, there were indeed increased B7-H1-positive cells in situ in the liver tissue from AHB. In vitro analysis showed the parallel upregulation of B7-H1 and CD40 on CD11c+ mDCs after the onset of stimulation. Addition of recombinant hepatitis B surface antigen (rHBsAg) significantly decreased CD40 expression (P < 0.05 at 16 h, 20 h and 24 h time points). B7-H1 expression was also inhibited by rHBsAg, and the inhibition rate of CD40 was greater than that of B7-H1. This preferential inhibition of CD40 expression on mDCs by rHBsAg resulted in the dysfunction of mDCs and T cells in the mixed leucocyte reaction (MLR) system. With rHBsAg pretreatment, in a carboxyfluorescein diacetate succinimidyl ester (CFSE) labeled MLR system at a ratio of 1:5 responder cell-stimulator cell (R/S), the CFSE",
        "keywords": [
            "Co-stimulatory molecule",
            "Hepatitis B",
            "Hepatitis B virus",
            "Human B7 homolog 1",
            "Immune tolerance"
        ],
        "venue": "World Journal of Gastroenterology",
        "year": 2012,
        "id": "bXN8PnTv"
    },
    "IL8kBofs": {
        "authors": [
            {
                "name": "Ming-Chun Lai",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Zhe Yang",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Qian-Qian Zhu",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Hai-Yang Xie",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Feng Zhang",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Li-Ming Wu",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Lei-Ming Chen",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            }
        ],
        "title": "Long non-coding RNA MALAT-1 overexpression predicts tumor recurrence of hepatocellular carcinoma after liver transplantation",
        "abstract": "Metastasis-associated lung adenocarcinoma transcript 1(MALAT1), a long non-coding RNA (lncRNA), is up-regulated in many solid tumors and associated with cancer metastasis and recurrence. However, its role in hepatocellular carcinoma (HCC) remains poorly understood. In the present study, we evaluated the expression of MALAT1 by quantitative real-time PCR in 9 liver cancer cell lines and 112 HCC cases including 60 cases who received liver transplantation (LT) with complete followup data. Moreover, small interfering RNA (siRNA) was used to inhibit MALAT1 expression to investigate its biological role in tumor progression. We found that MALAT1 was up-regulated in both cell lines and clinical tissue samples. Patients with high expression level of MALAT1 had a significantly increased risk of tumor recurrence after LT, particularly in patients who exceeded the Milan criteria. On multivariate analysis, MALAT1 was an independent prognostic factor for predicting HCC recurrence (hazard ratio, 3.280, P = 0.003). In addition, inhibition of MALAT1 in HepG2 cells could effectively reduce cell viability, motility, invasiveness, and increase the sensitivity to apoptosis. Our data suggest that lncRNA MALAT1 play an important role in tumor progression and could be a novel biomarker for predicting tumor recurrence after LT and serve as a promising therapeutic target. \u00a9 Springer Science+Business Media, LLC 2011.",
        "keywords": [
            "Hepatocellular carcinoma",
            "Liver transplantation",
            "MALAT1",
            "Recurrence",
            "Transplantation"
        ],
        "venue": "Medical Oncology",
        "year": 2012,
        "id": "IL8kBofs"
    },
    "ohhihbpF": {
        "authors": [
            {
                "name": "Kang-Jie Chen",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Hai-Yang Xie",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Taki-Eldin Ahmed",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Xiao-Wen Feng",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            }
        ],
        "title": "Intratumoral regulatory T cells alone or in combination with cytotoxic T cells predict prognosis of hepatocellular carcinoma after resection",
        "abstract": "Tumor-infiltrating lymphocytes (TILs) represent the host immune response to cancer. CD8",
        "keywords": [
            "Cytotoxic T cells, prognosis",
            "Hepatocellular carcinoma",
            "Regulatory T cells",
            "Tumor-infiltrating lymphocyte"
        ],
        "venue": "Medical Oncology",
        "year": 2012,
        "id": "ohhihbpF"
    },
    "jXNItYND": {
        "authors": [
            {
                "name": "Zhi-Yuan Xu",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Song-Ming Ding",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Hai-Yang Xie",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Kang-Jie Chen",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Wu Zhang",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Chun-Yan Xing",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Hai-Jun Guo",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            }
        ],
        "title": "FOXC1 contributes to microvascular invasion in primary hepatocellular carcinoma via regulating epithelial-mesenchymal transition",
        "abstract": "The existence of microvascular invasion (MVI) formation is one of the most important risk factors predicting poor outcome in hepatocellular carcinoma (HCC) and its mechanism remains largely unknown. Epithelial-Mesenchymal Transition (EMT) has been suggested to be involved in many steps of the invasion-metastasis cascade. To elucidate the possible contri-bution of EMT to MVI, we initially evaluated the expression of 8 EMT-related transcription factors (TFs) in HCC patients with or without MVI and found that FOXC1 expression was significantly higher in patients with MVI than those without MVI (P < 0.05). Knockdown of FOXC1 expression in HCC cells resulted in a partial conversion of their EMT progresses, mainly regulating the mesenchymal component. Ectopic expression of snail, twist or TGF-\u03b21 could induce expression of FOXC1, but none of the expression of snail, twist, slug or TGF-\u03b2 was consistently down-regulated in response to FOXC1 silencing, suggesting FOXC1 might operate the downstream of other EMT regulators. In addition, knockdown of FOXC1 ex-pression led to cytoskeleton modification accompanied by decreased ability of cell prolifera-tion, migration, and invasion. Meanwhile, some matrix metalloproteinases (MMPs) and VEGF-A were also simultaneously down-regulated. Together, our findings demonstrate that FOXC1 is one of candidate predictive markers of MVI, and that inhibition of FOXC1 ex-pression can partially reverse EMT program, offering a potential molecular therapeutic target for reducing tumor metastasis in HCC patients. \u00a9 Ivyspring International Publisher.",
        "keywords": [
            "Epithelial-Mesenchymal Transi-tion",
            "FOXC1",
            "Hepatocellular carcinoma",
            "Microvascular invasion"
        ],
        "venue": "International Journal of Biological Sciences",
        "year": 2012,
        "id": "jXNItYND"
    },
    "PJBUtZoa": {
        "authors": [
            {
                "name": "Li-Ming Jin",
                "org": "Department of General Surgery"
            },
            {
                "name": "Shui-Fang Jin",
                "org": "Intensive Care Unit"
            },
            {
                "name": "Yuan-Xing Liu",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Hai-Yang Xie",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Sheng Yan",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Xiao Xu",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            }
        ],
        "title": "Ischemic preconditioning enhances hepatocyte proliferation in the early phase after ischemia under hemi-hepatectomy in rats",
        "abstract": "Background: Ischemia/reperfusion (I/R) injury is an important barrier to liver surgery and transplantation because it impairs remnant liver/reduced-size-graft regeneration. Ischemic preconditioning (IPC), as an effective measure to overcome I/R injury, has been shown to enhance the regenerative capacity of hepatocytes. However, investigations have always focused on regeneration in the late phase after reperfusion. This study aimed to investigate whether IPC enhances hepatocyte proliferation in the early phase after reperfusion and possible underlying mechanisms. Methods: A total of 90 rats were divided into three groups: Hemi-hepatectomy alone (PHx group), 60 minutes of ischemia plus hemi-hepatectomy (I/R group), and a cycle of 10 minutes of alternating I/R prior to 60 minutes of ischemia plus hemihepatectomy (IPC group). Each group was divided into five subgroups sacrificed after 0.5, 2, 6, 12 or 24 hours (n=6/ subgroup). Subsequently, serum concentrations of alanine aminotransferase (ALT), aspartate aminotransferase (AST), tumor necrosis factor-alpha (TNF-\u03b1), and interleukin-6 (IL-6) were measured; caspase-3 and proliferating cell nuclear antigen (PCNA) proteins were also determined by Western blotting. Furthermore, PCNA was detected by immunohistochemistry to identify the expression site. Results: Serum ALT and AST levels after 2-24 hours of reperfusion in the PHx and IPC groups were remarkably decreased compared to the I/R group, and the serum TNF-\u03b1 was relatively lower. A significant increase of serum IL-6 levels was found in the PHx and IPC groups compared with the I/R group at each time point. Furthermore, PCNA expression was remarkably increased in the IPC group after 6-12 hours of reperfusion, and in the earlier 0.5 and 6 hours time points after reperfusion have shown the massive PCNA-positive hepatocytes. At the same time, the expression of liver p-JNK was higher in the IPC group in the early phase after reperfusion than that of the I/R group and its expression was consistent with the PCNA. Conclusion: IPC can initiate hepatocyte proliferation in the early phase after ischemia under hemi-hepatectomy, and may be associated with p-JNK expression and triggered by TNF-\u03b1/IL-6 signals. \u00a9 2012, Hepatobiliary Pancreat Dis Int.",
        "keywords": [
            "Hemi-hepatectomy",
            "Hepatocytes",
            "Ischemic preconditioning",
            "Proliferation",
            "Reperfusion injury"
        ],
        "venue": "Hepatobiliary and Pancreatic Diseases International",
        "year": 2012,
        "id": "PJBUtZoa"
    },
    "wUSneHyq": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Green Chemistry and Technology"
            },
            {
                "name": "Xiaohua Liu",
                "org": "Key Laboratory of Green Chemistry and Technology"
            },
            {
                "name": "Jie Ji",
                "org": "Key Laboratory of Green Chemistry and Technology"
            },
            {
                "name": "Yuheng Zhang",
                "org": "Key Laboratory of Green Chemistry and Technology"
            },
            {
                "name": "Xiaolei Hu",
                "org": "Key Laboratory of Green Chemistry and Technology"
            },
            {
                "name": "Lili Lin",
                "org": "Key Laboratory of Green Chemistry and Technology"
            },
            {
                "name": "Xiaoming Feng",
                "org": "Key Laboratory of Green Chemistry and Technology"
            }
        ],
        "title": "Enantioselective baeyer-villiger oxidation: Desymmetrization of meso cyclic ketones and kinetic resolution of racemic 2-arylcyclohexanones",
        "abstract": "Catalytic enantioselective Baeyer-Villiger (BV) oxidations of racemic and meso cyclic ketones were achieved in the presence of chiral N,N'-dioxide-Sc ",
        "keywords": [
            ""
        ],
        "venue": "Journal of the American Chemical Society",
        "year": 2012,
        "id": "wUSneHyq"
    },
    "St7MyhQx": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Department of Neurology"
            },
            {
                "name": "Ying Hou",
                "org": "Department of Neurology"
            },
            {
                "name": "Qidong Yang",
                "org": "Department of Neurology"
            },
            {
                "name": "Xiaoping Du",
                "org": "Department of Neurology"
            },
            {
                "name": "Min Li",
                "org": "Department of Neurology"
            },
            {
                "name": "Mei Yuan",
                "org": "Department of Neurology"
            },
            {
                "name": "Zhiwen Zhou",
                "org": "Department of Neurology"
            }
        ],
        "title": "Tetrahydroxystilbene glucoside improves the learning and memory of amyloid-\u03b2",
        "abstract": "The aim of this study was to evaluate the protective effects of 2,3,5,4\u2032-tetrahydroxystilbene-2-O-\u03b2-D-glucoside (TSG), an active component extracted from Polygonum multiflorum, on learning/memory deficits in Alzheimer's disease (AD). We randomly divided 24 male Sprague-Dawley rats among 4 groups: (i) the sham-operated group (control); (ii) sham-operated group also treated with TSG (sham_TSG); (iii) beta amyloid treated group (A\u03b2); and (iv) A\u03b2 treatment group also treated with TSG (A\u03b2+TSG). Rats in the A\u03b2 and A\u03b2+TSG groups were treated with A\u03b2",
        "keywords": [
            "2",
            "3",
            "4\u2032-tetrahydroxystilbene-2-o-\u03b2-d-glucoside (TSG)",
            "5",
            "Alzheimer's disease (AD)",
            "NR2B",
            "Src",
            "Synapse"
        ],
        "venue": "Canadian Journal of Physiology and Pharmacology",
        "year": 2012,
        "id": "St7MyhQx"
    },
    "6vKT13Gm": {
        "authors": [
            {
                "name": "Yongping Yang",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Chunping Wang",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Yinying Lu",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Wenlin Bai",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Linjing An",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Jianhui Qu",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Xudong Gao",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Yan Chen",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Lin Zhou",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Yu Wu",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Yongyi Feng",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Minna Zhang",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Xiujuan Chang",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            },
            {
                "name": "Jiyun Lv",
                "org": "Center of Therapeutic Research for Hepatocellular Carcinoma"
            }
        ],
        "title": "Outcomes of ultrasound-guided percutaneous argon-helium cryoablation of hepatocellular carcinoma",
        "abstract": "Purpose To evaluate the efficacy and safety of ultrasound (US)-guided percutaneous argon-helium cryoablation for hepatocellular carcinoma (HCC) and determine appropriate indications. Methods We reviewed outcomes of 300 HCC patients who underwent US-guided percutaneous cryoablation. Results Overall, 223 tumors (mean diameter 7.2 \u00b1 2.8 cm) in 165 patients were incompletely ablated, while 185 tumors (mean diameter 5.6 \u00b1 0.8 cm, P = 0.0001 vs. incomplete ablation) in 135 patients were completely ablated. Nineteen patients (6.3%) developed serious complications while in hospital, including cryoshock syndrome in six patients, hepatic bleeding in five, stress-induced gastric bleeding in four, liver abscess in one and intestinal fistulas in one. Two patients died because of liver failure. The median follow-up was 36.7 months (range 6-63 months). The local tumor recurrence rate was 31%, and was related to tumor size (P = 0.029) and tumor location (P = 0.037). The mean survival duration of patients with early, intermediate and advanced HCC (Barcelona Clinic Liver Cancer staging system) was 45.7 \u00b1 3.8, 28.4 \u00b1 1.2 and 17.7 \u00b1 0.6 months, respectively. Conclusions US-guided percutaneous cryoablation is a relatively safe and effective therapy for selected HCC patients. \u00a9 The Author(s) 2011.",
        "keywords": [
            "Cryoablation",
            "Efficacy",
            "Hepatocellular carcinoma",
            "Safety",
            "Treatment"
        ],
        "venue": "Journal of Hepato-Biliary-Pancreatic Sciences",
        "year": 2012,
        "id": "6vKT13Gm"
    },
    "gYMPSxKX": {
        "authors": [
            {
                "name": "Junjie Li",
                "org": "Molecular Small Animal Imaging Centre/MoSAIC"
            },
            {
                "name": "Marlein Miranda Cona",
                "org": "Molecular Small Animal Imaging Centre/MoSAIC"
            },
            {
                "name": "Feng Chen",
                "org": "Molecular Small Animal Imaging Centre/MoSAIC"
            },
            {
                "name": "Yuanbo Feng",
                "org": "Molecular Small Animal Imaging Centre/MoSAIC"
            },
            {
                "name": "Lin Zhou",
                "org": "Nuclear Medicine and Medical Imaging"
            },
            {
                "name": "Jie Yu",
                "org": "Theragnostic Laboratory"
            },
            {
                "name": "Johan Nuyts",
                "org": "Nuclear Medicine and Medical Imaging"
            },
            {
                "name": "Peter de Witte",
                "org": "Faculty of Pharmaceutical Sciences"
            },
            {
                "name": "Jian Zhang",
                "org": "Laboratory of Translational Medicine"
            },
            {
                "name": "Uwe Himmelreich",
                "org": "Molecular Small Animal Imaging Centre/MoSAIC"
            },
            {
                "name": "Alfons Verbruggen",
                "org": "Faculty of Pharmaceutical Sciences"
            },
            {
                "name": "Yicheng Ni",
                "org": "Laboratory of Translational Medicine"
            }
        ],
        "title": "Exploring Theranostic Potentials of Radioiodinated Hypericin in Rodent Necrosis Models",
        "abstract": "Objectives: The present animal experiments were conducted to evaluate radioiodinated Hypericin (Hyp) for its regional distribution as well as theranostic potentials. Materials and Methods: Rat models of reperfused liver infarction (RLI) and hepatic rhabdo-myosarcoma (R1) were surgically induced. R1 models received Combretastatin A4 phosphate (CA4P) intravenously at 10 mg/kg 24 h prior to radioiodinated Hyp. Three groups of 6 rats each containing 3 RLI and 3 R1 models received iv injections of 123I-Hyp at 37, 74, and 185 MBq/kg respectively and followed by 0.1 ml of 1% Evans blue solution were sacrificed at 4, 24 and 48 hour post injection immediately after in vivo examination of MRI and planar gamma scintigraphy. Besides, two groups of 6 R1 models that received either 300 MBq/kg of 131I-Hyp or vehicle intravenously were examined using MRI to compare tumor growth for 12 days. Autoradiography, gamma counting, and histopathology were performed for postmortem verifications and quantification. Results: Necrosis as seen in vivo on contrast-enhanced MRI corresponded well with the hot spots on planar scintigraphy. Autoradiography and gamma counting revealed intense accu-mulation of ",
        "keywords": [
            "Malignancies",
            "Necrosis avidity",
            "Radioiodinated hypericin",
            "Theranostic"
        ],
        "venue": "Theranostics",
        "year": 2012,
        "id": "gYMPSxKX"
    },
    "NxHzs8ph": {
        "authors": [
            {
                "name": "Jie Liang",
                "org": "Xijing Hospital of Digestive Diseases"
            },
            {
                "name": "Lin Zhou",
                "org": "Xijing Hospital of Digestive Diseases"
            },
            {
                "name": "Sumei Sha",
                "org": "Xijing Hospital of Digestive Diseases"
            },
            {
                "name": "Shaoni Lei",
                "org": "Xijing Hospital of Digestive Diseases"
            },
            {
                "name": "Guanhong Luo",
                "org": "Xijing Hospital of Digestive Diseases"
            },
            {
                "name": "Kaichun Wu",
                "org": "Xijing Hospital of Digestive Diseases"
            }
        ],
        "title": "Interpretation of the consensus on diagnosis and management of inflammatory bowel disease (Guangzhou, 2012) from the perspective of diagnosis of ulcerative colitis",
        "abstract": "Ulcerative colitis (UC) is a chronic non-specific inflammatory disease causing continuous and diffuse mucosal inflammation of the colon. Progress has been made in the clinical diagnosis, treatment and the related studies of the disease in recent years. New examination methods were invented, more extraintestinal manifestations were recognized, new susceptible factors and specific markers were identified, and mucosal healing concept was emphasized for clinical evaluation. Based on the \"Consensus on Diagnosis and Management of Inflammatory Bowel Disease (Guangzhou, 2012)\", an interpretation on the diagnosis of UC was made for helping the clinicians to improve their understanding of the new consensus.",
        "keywords": [
            "Colitis, ulcerative",
            "Diagnosis",
            "Mucosal healing"
        ],
        "venue": "Chinese Journal of Gastroenterology",
        "year": 2012,
        "id": "NxHzs8ph"
    },
    "yplOGOjp": {
        "authors": [
            {
                "name": "Yunlong Li",
                "org": "Key Lab of Applied Chemistry of Zhejiang Province"
            },
            {
                "name": "Hui Li",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Liping Xiao",
                "org": "Key Lab of Applied Chemistry of Zhejiang Province"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Jianzhong Shentu",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Xumin Zhang",
                "org": "Zeo-Innov Medical Technology Corporation"
            },
            {
                "name": "Jie Fan",
                "org": "Key Lab of Applied Chemistry of Zhejiang Province"
            }
        ],
        "title": "Hemostatic efficiency and wound healing properties of natural zeolite granules in a lethal rabbit model of complex groin injury",
        "abstract": "Quikclot has been used many years for treating external hemorrhage in the battle field. In this study, the hemostatic performance of NZG-JY (natural zeolite granules from Jinyun, China) was evaluated and compared with Quikclot in a lethal rabbit model of complex groin injury. Fifty-six anesthetized rabbits were randomized to three different groups: (1) NZG-JY (n = 19); (2) Quikclot (n = 19); and (3) medical gauze (n = 18). Survival was recorded three hours after the application of the hemostatic agents. The wound healing properties of the survived animals (n = 4 for each group) were observed a week later. The clotting efficiency is 100% for the animals in the NZG-JY and the Quikclot group, while only 5.6% in the gauze group. The mortality in the NZG-JY group (21.0%) is significantly less than that in the Quikclot group (52.6%) and the gauze group (66.7%). A good healing property was achieved in all animals that survived in the NZG-JY group, while three quarters of the animals in the Quikclot group had serious necrotic tissue.NZG-JY significantly decreases the mortality in a lethal rabbit model of complex groin injury and demonstrates good healing properties. \u00a9 2012 by the authors.",
        "keywords": [
            "Groin injury",
            "Hemostatic efficiency",
            "Mortality",
            "Natural zeolite",
            "Wound healing"
        ],
        "venue": "Materials",
        "year": 2012,
        "id": "yplOGOjp"
    },
    "4ot77BPW": {
        "authors": [
            {
                "name": "Ahmed Taki-Eldin",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Hai-Yang Xie",
                "org": ""
            },
            {
                "name": "Kang-Jie Chen",
                "org": ""
            },
            {
                "name": "Da Yu",
                "org": ""
            },
            {
                "name": "Yong He",
                "org": ""
            },
            {
                "name": "Shu-Sen Zheng",
                "org": ""
            }
        ],
        "title": "Triiodothyronine attenuates hepatic ischemia/reperfusion injury in a partial hepatectomy model through inhibition of proinflammatory cytokines, transcription factors, and adhesion molecules",
        "abstract": "Background: Hepatic ischemia/reperfusion (I/R) injury during liver surgery and transplantation is the main cause of postoperative liver failure and primary graft nonfunction, with subsequent rise in mortality in these patients. Triiodothyronine (T3) is a known hepatic mitogen. In this study we questioned whether exogenous administration of T3 protects against warm hepatic I/R injury. Materials and methods: T3 or vehicle was administered to male Sprague-Dawley rats (single dose of 0.5 mg/kg intraperitoneally) 48 h before hepatic ischemia, then the rats were subjected to 60 min of partial hepatic I/R followed by 50% hepatectomy. Serum transaminases, histopathologic changes, apoptosis, malondialdehyde, and myeloperoxidase were evaluated. The expression of proinflammatory cytokines (TNF-\u03b1, IL-1\u03b2, and IL-6), transcription factors (NF-\u03baB and AP-1), and adhesion molecules (ICAM-1, VCAM-1) was also investigated. Results: Rats pretreated with T3 showed significant reduction of their postischemic hepatic injury (serum transaminases, liver necrosis, and apoptosis). Also, production of reactive oxygen species and neutrophil infiltration were markedly depressed by T3 administration. This was associated with downregulation of proinflammatory cytokines, transcription factors, and adhesion molecules. Conclusions: This study illustrated that T3 protects against hepatic I/R injury, an effect that is mediated through inhibition of proinflammatory cytokines, transcription factors, and adhesion molecules. Pretreatment with T3 may represent a promising pharmacologic strategy for protection against hepatic I/R injury. \u00a9 2012 Elsevier Inc. All rights reserved.",
        "keywords": [
            "Adhesion molecules",
            "Hepatic ischemia/reperfusion injury",
            "Hepatic mitogen",
            "Proinflammatory cytokines",
            "T3"
        ],
        "venue": "Journal of Surgical Research",
        "year": 2012,
        "id": "4ot77BPW"
    },
    "m7nPYzWB": {
        "authors": [
            {
                "name": "Jufeng Zhang",
                "org": "School of Life Science"
            },
            {
                "name": "Ying Wang",
                "org": "Biomedical Research Institute"
            },
            {
                "name": "Pingping Zhen",
                "org": "Key Lab of Animal Ecology and Conservation Biology"
            },
            {
                "name": "Xia Luo",
                "org": "College of Engineering"
            },
            {
                "name": "Chao Zhang",
                "org": "Biomedical Research Institute"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Life Science"
            },
            {
                "name": "Yanxin Lu",
                "org": "Biomedical Research Institute"
            },
            {
                "name": "Yang Yang",
                "org": "Biomedical Research Institute"
            },
            {
                "name": "Wei Zhang",
                "org": "Biomedical Research Institute"
            },
            {
                "name": "Jun Wan",
                "org": "Division of Life Science"
            }
        ],
        "title": "Genome-Wide Analysis of miRNA Signature Differentially Expressed in Doxorubicin-Resistant and Parental Human Hepatocellular Carcinoma Cell Lines",
        "keywords": [
            ""
        ],
        "venue": "PLoS ONE",
        "year": 2013,
        "id": "m7nPYzWB"
    },
    "iCIpqtAR": {
        "authors": [
            {
                "name": "Chunyang Xing",
                "org": "Key Lab of Combined Multi-organ Transplantation"
            },
            {
                "name": "Wuhua Zhou",
                "org": "Department of General Surgery"
            },
            {
                "name": "Songming Ding",
                "org": "Key Lab of Combined Multi-organ Transplantation"
            },
            {
                "name": "Haiyang Xie",
                "org": "Key Lab of Combined Multi-organ Transplantation"
            },
            {
                "name": "Wu Zhang",
                "org": "Department of General Surgery"
            },
            {
                "name": "Zhe Yang",
                "org": "Department of General Surgery"
            },
            {
                "name": "Bajin Wei",
                "org": "Department of General Surgery"
            },
            {
                "name": "Kangjie Chen",
                "org": "Department of General Surgery"
            },
            {
                "name": "Rong Su",
                "org": "Key Lab of Combined Multi-organ Transplantation"
            },
            {
                "name": "Jun Cheng",
                "org": "Department of General Surgery"
            },
            {
                "name": "Shusen Zheng",
                "org": "Key Lab of Combined Multi-organ Transplantation"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of General Surgery"
            }
        ],
        "title": "Reversing effect of ring finger protein 43 inhibition on malignant phenotypes of human hepatocellular carcinoma",
        "abstract": "It has been shown that Ring finger protein 43 (RNF43) is overexpressed in colorectal cancer and mediates cancer cell proliferation; however, its role in hepatocellular carcinoma (HCC) remains unknown. In this study, we found that RNF43 was frequently overexpressed in HCCs, and this overexpression was correlated with positive vascular invasion, poor tumor differentiation, and advanced tumor stage. Functional studies showed that knockdown of RNF43 could induce apoptosis and inhibit proliferation, invasion, colony formation, and xenograft growth of HCCs. Microarray-based gene profiling showed a total of 229 genes differentially expressed after RNF43 knockdown, many of which are involved in oncogenic processes such as cell proliferation, cell adhesion, cell motility, cell death, DNA repair, and so on. These results suggest that RNF43 is involved in tumorigenesis and progression of HCCs and that antagonism of RNF43 may be beneficial for HCC treatment. \u00a92012 AACR.",
        "keywords": [
            ""
        ],
        "venue": "Molecular Cancer Therapeutics",
        "year": 2013,
        "id": "iCIpqtAR"
    },
    "bun5URNB": {
        "authors": [
            {
                "name": "Yusheng Wang",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Yu Han",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Jian Yang",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Zhen Wang",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Li Liu",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Wei Wang",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Lin Zhou",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Dan Wang",
                "org": "Division of Nephrology and Hypertension, and Hypertension"
            },
            {
                "name": "Xuerui Tan",
                "org": "Department of Cardiology"
            },
            {
                "name": "Chunjiang Fu",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Pedro A. Jose",
                "org": "Division of Nephrology"
            },
            {
                "name": "Chunyu Zeng",
                "org": "Chongqing Institute of Cardiology"
            }
        ],
        "title": "Relaxant effect of all-trans-retinoic acid via NO-sGC-cGMP pathway and calcium-activated potassium channels in rat mesenteric artery",
        "keywords": [
            "All-trans-retinoic acid",
            "Blood pressure",
            "Mesenteric artery",
            "Nitric oxide synthase",
            "Vasorelaxation"
        ],
        "venue": "American Journal of Physiology - Heart and Circulatory Physiology",
        "year": 2013,
        "id": "bun5URNB"
    },
    "hCuBrOFb": {
        "authors": [
            {
                "name": "Zhijun Jiang",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Ying Chen",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Xiaonin Feng",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Jianwen Jiang",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Tianxiang Chen",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Haiyang Xie",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Shusen Zheng",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            }
        ],
        "title": "Hepatic stellate cells promote immunotolerance following orthotopic liver transplantation in rats via induction of T cell apoptosis and regulation of Th2/Th3-like cell cytokine production",
        "abstract": "Hepatic stellate cells (HSCs) have been demonstrated to have immunoinhibitory activity. The aim of this study was to investigate the role of HSCs in the development of immunotolerance following liver transplantation. A rat liver transplantation tolerance model [donor Lewis into recipient Dark Agouti (DA)] and rejection (donor DA into recipient Lewis) was established. On the 7th day following transplantation, the HSCs and T cells were isolated from the rats of either the tolerance or rejection group and cultured together. The apoptosis rate of the T cells was determined 24 h later by flow cytometry following staining with anti-CD3 mAb and Annexin V-FITC/PI. Additionally, the FasL expression of HSCs was determined by fow cytometry following staining with anti-FasL mAb. The protein levels of IL-2, TNF-\u03b1, TGF-\u03b2 and IL-10 in the supernatant collected from mixed lymphocyte reaction cultures of HSCs and T cells for 5 days were measured using ELISA assays. HSCs isolated from the tolerance group had a higher T-cell apoptosis induction activity compared with those of the rejection group. The activity of the HSCs was partially reversed by FasL blocking mAb. Accordingly, the FasL expression level of HSCs in the tolerance group was revealed to be higher than that of the rejection group. Moreover, HSCs stimulated IL-10 and TGF-\u03b2 production in the tolerance group. This study suggests that HSCs are involved in liver transplantation immune tolerance via the induction of T-cell apoptosis partially mediated by the Fas/FasL pathway and the activation of Th2/Th3-like cell cytokine production.",
        "keywords": [
            "Apoptosis",
            "Fas/FasL",
            "Hepatic stellate cells",
            "Immunotolerance",
            "Liver transplantation"
        ],
        "venue": "Experimental and Therapeutic Medicine",
        "year": 2013,
        "id": "hCuBrOFb"
    },
    "7TwVJ4Xg": {
        "authors": [
            {
                "name": "Zhen-Yu Ding",
                "org": "Department of Thoracic Oncology"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Thoracic Oncology"
            },
            {
                "name": "Yong-Mei Liu",
                "org": "Department of Thoracic Oncology"
            },
            {
                "name": "You Lu",
                "org": "Department of Thoracic Oncology"
            }
        ],
        "title": "Safety and efficacy of paclitaxel liposome for elderly patients with advanced non-small cell lung cancer: A multi-center prospective study",
        "abstract": "Background: Lung cancer in elderly patients poses an increasingly challenge for oncologists. The optimal treatment needs to be explored. The purpose of this study was to evaluate the safety and efficacy of the novel form of paclitaxel liposome for elderly patients with non-small cell lung cancer (NSCLC). Methods: This multi-center prospective trial recruited patients aged at least 70 years with advanced or recurrent NSCLC. Eligibility criteria included presence of measurable lesions, an Eastern Cooperative Oncology Group performance status of 0-2, as well as adequate organ function. Patients received paclitaxel liposome at the escalating dose of 135mg/m",
        "keywords": [
            "Elderly",
            "Non-small cell lung cancer",
            "Paclitaxel"
        ],
        "venue": "Thoracic Cancer",
        "year": 2013,
        "id": "7TwVJ4Xg"
    },
    "ubjG1UV0": {
        "authors": [
            {
                "name": "Li-Ming Wu",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Jun Xu",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Ba-Jin Wei",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Jun Cheng",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Xiao Xu",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Bin Xi",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Hai-Yang Xie",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            }
        ],
        "title": "Lack of association between genetic polymorphisms in cytokine genes and tumor recurrence in patients with hepatocellular carcinoma undergoing transplantation",
        "abstract": "BACKGROUND: Recurrence of hepatocellular carcinoma (HCC) after liver transplantation (LT) remains one of the most common causes of poor long-term survival. However, the host genetic factors affecting increased risk of tumor recurrence after transplantation have not been thoroughly elucidated. The present study was designed to investigate the association of cytokine gene polymorphisms with the risk of tumor recurrence in LT patients for HCC. METHODS: Eleven single-nucleotide polymorphisms within the promoter regions of 7 cytokine genes, i.e., the IL-1 family (IL-1\u03b1 and IL-1\u03b2), IL-6, IL-8, IL-10, TNF-\u03b1, and TGF-\u03b21, were genotyped in 93 HCC patients treated with LT using DNA sequencing. The association between these polymorphisms and the risk of tumor recurrence was evaluated while controlling confounding clinical variables. RESULTS: The genotype frequency of IL-10 -1082 A/G in patients with and without recurrence of HCC was AA 83.3%, GA 16.7% and AA 97.6%, GA 2.4%, respectively. The association between IL-10 -1082 GA and recurrence was significant (P=0.033). No other single-nucleotide polymorphism in the cytokine gene was found to be associated with recurrence. Kaplan-Meier survival curves showed that the homozygous AA patients had a significantly longer mean recurrence-free survival than heterozygous GA patients (23.5 vs 5.7 months, P=0.001). However, multivariate analysis failed to reveal that the GA genotype of IL-10 -1082 A/G was an independent indicator of recurrence. CONCLUSIONS: This study suggests the lack of association of selected cytokine gene polymorphisms with HCC recurrence after LT in the Han Chinese population. The finding does not exclude the idea that other cytokine polymorphisms could act as candidate biomarkers of disease prognosis. \u00a9 2013, Hepatobiliary Pancreat Dis Int.",
        "keywords": [
            "Cytokine",
            "Hepatocellular carcinoma",
            "Polymorphism",
            "Recurrence"
        ],
        "venue": "Hepatobiliary and Pancreatic Diseases International",
        "year": 2013,
        "id": "ubjG1UV0"
    },
    "qi78lWrL": {
        "authors": [
            {
                "name": "Qi Ling",
                "org": ""
            },
            {
                "name": "Haiyang Xie",
                "org": ""
            },
            {
                "name": "Di Lu",
                "org": ""
            },
            {
                "name": "Xuyong Wei",
                "org": ""
            },
            {
                "name": "Feng Gao",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Xiao Xu",
                "org": ""
            },
            {
                "name": "Shusen Zheng",
                "org": ""
            }
        ],
        "title": "Association between donor and recipient TCF7L2 gene polymorphisms and the risk of new-onset diabetes mellitus after liver transplantation in a Han Chinese population",
        "abstract": "Backgrounds & Aims: New-onset diabetes mellitus (NODM) is a frequent and serious complication arising after liver transplantation (LT). Transcription factor 7-like 2 (TCF7L2) polymorphisms have been reported to strongly associate with type 2 diabetes. In addition, the donor liver plays a vital role in regulating blood glucose levels. In this study, we aim at evaluating the association between donor and recipient TCF7L2 gene polymorphisms with NODM after LT. Methods: A total of 125 patients undergoing primary LT, without a history of diabetes were included. Four single nucleotide polymorphisms (rs290487, rs7903146, rs11196205, and rs12255372), closely associated with type 2 diabetes in the Eastern Asia population, were genotyped and analyzed. Results: Both donor and recipient rs290487 polymorphisms (CC vs. TT genotype) were found to be significantly associated with NODM. In multivariate analysis, donor rs290487 genetic variation (OR = 2.172 per each C allele, p = 0.015), blood tacrolimus levels at 1 month post-LT >10 ng/ml (OR = 3.264, p = 0.017), and recipient age >55 years (OR = 2.638, p = 0.043) were identified as independent risk factors of NODM. Furthermore, donor rs290487 CC genotype could predict a high probability (>40%) of the onset of NODM. Predictive model containing donor rs290487 polymorphism showed a significantly higher prognostic ability on NODM than the model with only clinical parameters (p = 0.031). Conclusions: Donor TCF7L2 rs290487 polymorphism is associated with an increased risk of NODM after LT and has a potential clinical value for the prediction of NODM. \u00a9 2012 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.",
        "keywords": [
            "Liver transplantation",
            "New-onset diabetes mellitus",
            "TCF7L2 polymorphism"
        ],
        "venue": "Journal of Hepatology",
        "year": 2013,
        "id": "qi78lWrL"
    },
    "OvBntgA0": {
        "authors": [
            {
                "name": "Jianxin Xue",
                "org": "Laboratory of Stem Cell Biology"
            },
            {
                "name": "Xin Li",
                "org": "Department of Thoracic Oncology"
            },
            {
                "name": "You Lu",
                "org": "Department of Thoracic Oncology"
            },
            {
                "name": "Lu Gan",
                "org": "Laboratory of Cellular and Molecular Biology"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Thoracic Oncology"
            },
            {
                "name": "Yongsheng Wang",
                "org": "Department of Thoracic Oncology"
            },
            {
                "name": "Jie Lan",
                "org": "Department of Thoracic Oncology"
            },
            {
                "name": "Shurui Liu",
                "org": "Department of Thoracic Oncology"
            },
            {
                "name": "Lan Sun",
                "org": "Department of Thoracic Oncology"
            },
            {
                "name": "Li Jia",
                "org": "Department of Thoracic Oncology"
            },
            {
                "name": "Xianming Mo",
                "org": "Laboratory of Stem Cell Biology"
            },
            {
                "name": "Jian Li",
                "org": "Center of Radiation Oncology"
            }
        ],
        "title": "Gene-modified mesenchymal stem cells protect against radiation-induced lung injury",
        "abstract": "Radiation-induced lung injury (RILI) presents a common and major obstacle in the radiotherapy of thoracic cancers. The aim of this study was to examine whether RILI could be alleviated by mesenchymal stem cells (MSCs) expressing soluble transforming growth factor-\u03b2 (TGF-\u03b2) type II receptor via an adenovirus (Ad-sT\u03b2R). Here, we systemically administered male MSCs into female mice challenged with thoracic irradiation. The data showed that either MSCs or Ad-sT\u03b2R transduced MSCs (Ad-sT\u03b2R-MSCs) specifically migrated into radiation-injured lung. Ad-sT\u03b2R-MSCs obviously alleviated lung injury, as reflected by survival and histopathology data, as well as the assays of malondialdehyde (MDA), hydroxyproline, plasma cytokines, and the expression of connective tissue growth factor (CTGF) and a-smooth muscle actin (a-SMA). Furthermore, MSCs and Ad-sT\u03b2R-MSCs could adopt the characteristics of alveolar type II (ATII) cells. However, the MSCs levels in the lungs were relatively low to account for the noted therapeutic effects, suggesting the presence of other mechanisms. In vivo, MSCs-conditioned medium (MSCs CM) significantly attenuated RILI. In vitro, MSCs CM protected ATII cells against radiation-induced apoptosis and DNA damage, and modulated the inflammatory response, indicating the beneficial effects of MSCs are largely due to its paracrine activity. Our results provide a novel insight for RILI therapy that currently lack efficient treatments. \u00a9 The American Society of Gene &Cell Therapy.",
        "keywords": [
            ""
        ],
        "venue": "Molecular Therapy",
        "year": 2013,
        "id": "OvBntgA0"
    },
    "ULhey9zu": {
        "authors": [
            {
                "name": "Xiaoying Zhang",
                "org": "Department of Physiology"
            },
            {
                "name": "Christopher Szeto",
                "org": "Department of Physiology"
            },
            {
                "name": "Erhe Gao",
                "org": "Department of Physiology"
            },
            {
                "name": "Mingxin Tang",
                "org": "Department of Physiology"
            },
            {
                "name": "Jianguo Jin",
                "org": "Department of Physiology"
            },
            {
                "name": "Qin Fu",
                "org": "Third Military Medical University"
            },
            {
                "name": "Catherine Makarewich",
                "org": "Department of Physiology"
            },
            {
                "name": "Xiaojie Ai",
                "org": "Department of Physiology"
            },
            {
                "name": "Ying Li",
                "org": "College of Biological Sciences"
            },
            {
                "name": "Allen Tang",
                "org": "Department of Physiology"
            },
            {
                "name": "Jenny Wang",
                "org": "Department of Physiology"
            },
            {
                "name": "Hui Gao",
                "org": "Department of Physiology"
            },
            {
                "name": "Fang Wang",
                "org": "Department of Physiology"
            },
            {
                "name": "Xinyi Joy Ge",
                "org": "Department of Physiology"
            },
            {
                "name": "Satya P. Kunapuli",
                "org": "Department of Physiology"
            },
            {
                "name": "Lin Zhou",
                "org": "College of Biological Sciences"
            },
            {
                "name": "Chunyu Zeng",
                "org": "College of Biological Sciences"
            },
            {
                "name": "Kevin Yang Xiang",
                "org": "Department of Pharmacology"
            },
            {
                "name": "Xiongwen Chen",
                "org": "Department of Physiology"
            }
        ],
        "title": "Cardiotoxic and cardioprotective features of chronic \u03b2-Adrenergic signaling",
        "abstract": "RATIONALE:: In the failing heart, persistent \u03b2-adrenergic receptor activation is thought to induce myocyte death by protein kinase A (PKA)-dependent and PKA-independent activation of calcium/calmodulin-dependent kinase II. \u03b2-adrenergic signaling pathways also are capable of activating cardioprotective mechanisms. OBJECTIVE:: This study used a novel PKA inhibitor peptide to inhibit PKA activity to test the hypothesis that \u03b2-adrenergic receptor signaling causes cell death through PKA-dependent pathways and cardioprotection through PKA-independent pathways. METHODS AND RESULTS:: In PKA inhibitor peptide transgenic mice, chronic isoproterenol failed to induce cardiac hypertrophy, fibrosis, and myocyte apoptosis, and decreased cardiac function. In cultured adult feline ventricular myocytes, PKA inhibition protected myocytes from death induced by \u03b21-adrenergic receptor agonists by preventing cytosolic and sarcoplasmic reticulum Ca overload and calcium/calmodulin-dependent kinase II activation. PKA inhibition revealed a cardioprotective role of \u03b2-adrenergic signaling via cAMP/exchange protein directly activated by cAMP/Rap1/Rac/extracellular signal-regulated kinase pathway. Selective PKA inhibition causes protection in the heart after myocardial infarction that was superior to \u03b2-blocker therapy. CONCLUSIONS:: These results suggest that selective block of PKA could be a novel heart failure therapy. \u00a9 2013 American Heart Association, Inc.",
        "keywords": [
            "apoptosis",
            "Ca2+/calmodulin-dependent protein kinase II",
            "cAMP",
            "exchange protein directly activated by cAMP",
            "extracellular signal-regulated kinases 1/2",
            "protein kinase A inhibition"
        ],
        "venue": "Circulation Research",
        "year": 2013,
        "id": "ULhey9zu"
    },
    "gIzWdRgA": {
        "authors": [
            {
                "name": "Zhijun Jiang",
                "org": ""
            },
            {
                "name": "Ying Chen",
                "org": ""
            },
            {
                "name": "Xiaonin Feng",
                "org": ""
            },
            {
                "name": "Haiyang Xie",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Shusen Zheng",
                "org": ""
            }
        ],
        "title": "Recipient cytotoxic T lymphocyte antigen 4 +49 single-nucleotide polymorphism is not associated with acute rejection after liver transplantation in Chinese population",
        "abstract": "Objective: Single-nucleotide polymorphisms (SNPs) in Cytotoxic T lymphocyte antigen 4 (CTLA-4) gene have been detected and proved to associate with the incidence of rejection after transplantation. However, previous studies gained inconsistent results about the association between CTLA-4 +49 single-nucleotide polymorphism and susceptibility of allograft rejection. Therefore we sought to clarify whether CTLA-4 +49 SNP influences the incidence of acute rejection after liver transplantation in Chinese population. Methods: Genomic DNA from 335 liver transplant recipients was genotyped for CTLA-4 +49 SNP by DNA sequencing. Acute rejection was confirmed by pathologic evidences. The association between CTLA-4 +49 SNP and incidence of acute rejection was then analyzed by dominant, recessive, codominant and overdominant models. Results: The incidence of acute rejection within the first 3 months was 11.9%. In acute rejectors, the frequency was 45% for G/G, 10% for A/A and 45% for A/G respectively, compared with 47.5% for G/G, 10.8% for A/A and 41.7% for A/G in non-acute rejectors. And no significant difference of allele distribution between these 2 groups was detected. Conclusions: This study suggests that CTLA-4 +49 SNP is not associated with acute rejection after liver transplantation in Chinese population. \u00a9 Ivyspring International Publisher.",
        "keywords": [
            "Cytotoxic T lymphocyte antigen 4",
            "Liver transplantation",
            "Single nucleotide polymor-phism"
        ],
        "venue": "International Journal of Medical Sciences",
        "year": 2013,
        "id": "gIzWdRgA"
    },
    "N8LvrEx4": {
        "authors": [
            {
                "name": "Jin Huang",
                "org": "Beijing Hospital"
            },
            {
                "name": "Liang Sun",
                "org": "Beijing Hospital"
            },
            {
                "name": "Ming Liu",
                "org": "Beijing Hospital"
            },
            {
                "name": "Lin Zhou",
                "org": "Beijing Teenager Science and Technology Club"
            },
            {
                "name": "Ze-Ping Lu",
                "org": "Guangxi Jiangbin Hospital"
            },
            {
                "name": "Cai-You Hu",
                "org": "Guangxi Jiangbin Hospital"
            },
            {
                "name": "Ze-Zhi Huang",
                "org": "Centers for Disease Control of Yongfu"
            },
            {
                "name": "Chen-Guang Zheng",
                "org": "Guangxi Jiangbin Hospital"
            },
            {
                "name": "Ze Yang",
                "org": "Beijing Hospital"
            }
        ],
        "title": "Association between SIRT1 gene polymorphisms and longevity of populations from Yongfu region of Guangxi",
        "abstract": "Objective: To assess the association between SIRT1 gene polymorphisms and the longevity phenomena in Yongfu region of Guangxi. Methods: In this case-control study, 500 individuals from Yongfu region of Guangxi were recruited. The subjects were divided into a longevity group (n=223, average age=93.17\u00b13.08 yr) and a healthy control group (n=277, average age=46.92\u00b117.12 yr). Polymerase chain reaction-high resolution melting curve (PCR-HRM) and DNA sequencing were used to determine the allelic and genotypic frequencies of rs3758391, rs3740051, rs2273773, rs4746720 and rs10997870 polymorphisms of SIRT1 gene in the two groups. The association between above polymorphisms and longevity was assessed. Results: In the longevity group, CT genotype of the rs4746720 locus was significantly more common than CC and TT genotypes (P=0.000, OR=2.098, 95% CI:1.412-4.117). However, no significant difference was found in the allelic and genotypic frequencies of rs3758391, rs3740051 and rs2273773 between the two groups. Conclusion: There is an association between rs4746720 of SIRT1 gene and longevity in Yongfu region of Guangxi.",
        "keywords": [
            "Association analysis",
            "Longevity",
            "Single nucleotide polymorphism",
            "SIRT1 gene"
        ],
        "venue": "Chinese Journal of Medical Genetics",
        "year": 2013,
        "id": "N8LvrEx4"
    },
    "T9J6jxlF": {
        "authors": [
            {
                "name": "Jian Yang",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Yu Han",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Caiyu Chen",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Hailan Sun",
                "org": "Department of Nutrition"
            },
            {
                "name": "Duofen He",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Jing Guo",
                "org": "Department of Nutrition"
            },
            {
                "name": "Baoquan Jiang",
                "org": "Department of Nutrition"
            },
            {
                "name": "Lin Zhou",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Chunyu Zeng",
                "org": "Chongqing Institute of Cardiology"
            }
        ],
        "title": "EGCG attenuates high glucose-induced endothelial cell inflammation by suppression of PKC and NF-\u03baB signaling in human umbilical vein endothelial cells",
        "abstract": "Aims Vascular inflammation is a key factor in the pathogenesis of diabetes-related vascular complications. Our previous study showed that (-)-epigallocatechin-3-gallate (EGCG) inhibits high glucose-induced vascular smooth muscle cell proliferation, thus it may have beneficial effects in diabetes and its complications. However, the effect of EGCG on inflammation in diabetes is not known. In the present study, we investigated whether EGCG suppresses the vascular inflammation induced by high glucose in human umbilical vein endothelial cells (HUVECs). Main methods The inhibitory effect of EGCG on high glucose-induced up-regulation of the expression of vascular cell adhesion molecule 1 (VCAM-1) was measured using enzyme-linked immunosorbent, RT-PCR, immunoblotting and cell adhesion assays. The effect of EGCG on high glucose-induced nuclear factor-kappa B (NF-\u03baB) activation was investigated by immunoblotting, immunofluorescence and electrophoretic mobility shift assays. Key findings High glucose increased VCAM-1 expression and enhanced the adhesion of monocytes to HUVECs. Pretreatment with EGCG in a concentration-dependent manner (1.0-50 \u03bcM) significantly attenuated these effects. High glucose (25 mM)-mediated vascular inflammation was blocked by PKC pseudosubstrate (PKC inhibitor 19-31) or the NF-\u03baB inhibitor pyrrolidine dithiocarbamate (PDTC). Stimulation with high glucose increased the NF-\u03baB translocation from the cytoplasm to the nucleus, and increased I\u03baB-\u03b1 phosphorylation, decreased its expression, and in the presence of EGCG, the effect of high glucose on NF-\u03baB and I\u03baB-\u03b1 were blocked. Significance EGCG suppresses high glucose-induced vascular inflammatory process via the inhibition of PKC and NF-\u03baB activation in HUVECs, suggesting that EGCG may be a potential candidate for the treatment and prevention of diabetic vascular complications. \u00a9 2013 Elsevier Inc.",
        "keywords": [
            "EGCG",
            "High glucose",
            "Human umbilical vein endothelial cells",
            "Vascular cell adhesion molecule-1",
            "Vascular inflammation"
        ],
        "venue": "Life Sciences",
        "year": 2013,
        "id": "T9J6jxlF"
    },
    "EUwzmTJD": {
        "authors": [
            {
                "name": "Sheng Gao",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Zhe Yang",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Zhi-Yun Zheng",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Jia Yao",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Feng Zhang",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Li-Ming Wu",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Hai-Yang Xie",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Lin zhou",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            }
        ],
        "title": "Reduced expression of DACT2 promotes hepatocellular carcinoma progression: Involvement of methylation-mediated gene silencing",
        "abstract": "Background: Hepatocellular carcinoma (HCC) is one of the most aggressive malignancies in humans, and its prognosis is generally poor even after surgery. Many advances have been made to understand the pathogenesis of HCC; however, the molecular mechanisms that lead to hepatocarcinogenesis and progression are still not clearly understood.Methods: The expression of DACT2 in specimens from 30 paired HCCs and an additional 61 HCC patients after liver transplantation was evaluated by quantitative RT-PCR and immunohistochemical analysis. We investigated the methylation status of the DACT2 promoter region. We also analyzed the alterations of the cell cycle, migration and invasion after DACT2 knockdown.Results: The expression level of DACT2 was significantly lower in HCC tissues than in non-cancerous tissues. Reduced DACT2 expression was associated with large tumor size. DACT2 transcripts were at low levels in hypermethylated liver cancer cells and were restored by exposure to a demethylating agent. Reduced expression of DACT2 in MHCC97L cells induced G1/S arrest, increased cell proliferation, and promoted cell invasion.Conclusions: Our study suggests that DACT2 is silenced by promoter hypermethylation, and reduced DACT2 can promote liver cancer progression. DACT2 may serve as a novel tumor suppressor gene in HCC. \u00a9 2013 Gao et al.; licensee BioMed Central Ltd.",
        "keywords": [
            "DACT2",
            "Hepatocellular carcinoma",
            "Methylation",
            "Progression"
        ],
        "venue": "World Journal of Surgical Oncology",
        "year": 2013,
        "id": "EUwzmTJD"
    },
    "UegEfvFe": {
        "authors": [
            {
                "name": "Yi Shen",
                "org": "Departments of Otolaryngology and Head and Neck, Ningbo Medical Centre, Ningbo Lihuili Hospital"
            },
            {
                "name": "Sharon Leanne Redmond",
                "org": "Ear Science Institute Australia"
            },
            {
                "name": "Bing Mei Teh",
                "org": "Ear Science Institute Australia"
            },
            {
                "name": "Sheng Yan",
                "org": "Department of Surgery, Ministry of Public Health, Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Yan Wang",
                "org": "Department of Surgery, Ministry of Public Health, Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Surgery, Ministry of Public Health, Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Charley A. Budgeon",
                "org": "Centre for Applied Statistics, University of Western Australia"
            },
            {
                "name": "Robert Henry Eikelboom",
                "org": "Ear Science Institute Australia"
            },
            {
                "name": "Marcus David Atlas",
                "org": "Ear Science Institute Australia"
            },
            {
                "name": "Rodney James Dilley",
                "org": "Ear Science Institute Australia"
            },
            {
                "name": "Minghao Zheng",
                "org": "Centre for Orthopaedics Research, School of Surgery (M508), University of Western Australia"
            },
            {
                "name": "Robert Jeffery Marano",
                "org": "Ear Science Institute Australia"
            }
        ],
        "title": "Scaffolds for tympanic membrane regeneration in rats",
        "abstract": "Tympanic membrane (TM) perforations lead to significant hearing loss and result in possible infection of the middle ear. Myringoplasty is commonly performed to repair chronic perforations. Although various grafts and materials have been used to promote TM regeneration, all have associated limitations. The aim of this study was to evaluate the efficacy and feasibility of two graft materials, silk fibroin scaffold (SFS) and porcine-derived acellular collagen type I/III scaffold (ACS), compared with two commonly used graft materials (paper patch and Gelfoam) for the promotion of TM regeneration. These scaffolds were implanted using on-lay myringoplasty in an acute TM perforation rat model. Surface morphology of the scaffolds was observed with scanning electron microscopy. The morphology of the TM was assessed at various time points postimplantation using otoscopy, light and electron microscopy, and functional outcomes by auditory brainstem responses. We found that SFS and ACS significantly accelerated the TM perforation closure, obtained optimal TM thickness, and resulted in better trilaminar morphology with well-organized collagen fibers and early restoration of hearing. However, paper patch and Gelfoam lost their scaffold function in the early stages and showed an inflammatory response, which may have contributed to delayed healing. This study indicates that compared with paper patch and Gelfoam, SFS and ACS are more effective in promoting an early TM regeneration and an improved hearing, suggesting that these scaffolds may be potential substitutes for clinical use. \u00a9 Copyright 2013, Mary Ann Liebert, Inc. 2013.",
        "keywords": [
            ""
        ],
        "venue": "Tissue Engineering - Part A",
        "year": 2013,
        "id": "UegEfvFe"
    },
    "HmwYEZTj": {
        "authors": [
            {
                "name": "Xiao Xu",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Xiaoli Liu",
                "org": "State Key Laboratory for Diagnosis and Treatment of Infectious Diseases"
            },
            {
                "name": "Qi Ling",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Qiang Wei",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Zhikun Liu",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Xiaowei Xu",
                "org": "State Key Laboratory for Diagnosis and Treatment of Infectious Diseases"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Min Zhang",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Jian Wu",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Jianrong Huang",
                "org": "State Key Laboratory for Diagnosis and Treatment of Infectious Diseases"
            },
            {
                "name": "Jifang Sheng",
                "org": "State Key Laboratory for Diagnosis and Treatment of Infectious Diseases"
            },
            {
                "name": "Shusen Zheng",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Lanjuan Li",
                "org": "State Key Laboratory for Diagnosis and Treatment of Infectious Diseases"
            }
        ],
        "title": "Artificial Liver Support System Combined with Liver Transplantation in the Treatment of Patients with Acute-on-Chronic Liver Failure",
        "keywords": [
            ""
        ],
        "venue": "PLoS ONE",
        "year": 2013,
        "id": "HmwYEZTj"
    },
    "vZ9yI2Yo": {
        "authors": [
            {
                "name": "Lingli Tu",
                "org": "Department of Thoracic Oncology and State Key Laboratory of Biotherapy"
            },
            {
                "name": "Lan Sun",
                "org": "Department of Thoracic Oncology and State Key Laboratory of Biotherapy"
            },
            {
                "name": "Yong Xu",
                "org": "Department of Thoracic Oncology and State Key Laboratory of Biotherapy"
            },
            {
                "name": "Yongsheng Wang",
                "org": "Department of Thoracic Oncology and State Key Laboratory of Biotherapy"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Thoracic Oncology and State Key Laboratory of Biotherapy"
            },
            {
                "name": "Yongmei Liu",
                "org": "Department of Thoracic Oncology and State Key Laboratory of Biotherapy"
            },
            {
                "name": "Jiang Zhu",
                "org": "Department of Thoracic Oncology and State Key Laboratory of Biotherapy"
            },
            {
                "name": "Feng Peng",
                "org": "Department of Thoracic Oncology and State Key Laboratory of Biotherapy"
            },
            {
                "name": "Yuquan Wei",
                "org": "Department of Thoracic Oncology and State Key Laboratory of Biotherapy"
            },
            {
                "name": "Youling Gong",
                "org": "Department of Thoracic Oncology and State Key Laboratory of Biotherapy"
            }
        ],
        "title": "Paclitaxel and cisplatin combined with intensity-modulated radiotherapy for upper esophageal carcinoma",
        "abstract": "Purpose: This study was conducted to evaluate the effectiveness and safety of intensity-modulated radiotherapy (IMRT) and concurrent paclitaxel plus cisplatin (TP regimen) for upper esophageal carcinoma.Methods: 36 patients of upper esophageal carcinoma were retrospectively analyzed. Patients were treated with IMRT (median 60\u00a0Gy) combined with concurrent TP regimen chemotherapy. The Kaplan-Meier analysis was performed in statistical analysis. Toxicities were recorded according to the NCI CTC version 3.0.Results: 36 patients aged 43-73\u00a0years (median 57\u00a0years). The median follow-up period was 14.0\u00a0months. The 1-year and 2-year survival rates were 83.3% and 42.8% respectively. The median progression-free survival (PFS) time and overall survival (OS) time were 12.0 (95% CI: 7.8-16.2\u00a0months) and 18.0\u00a0months (95% CI: 9.9-26.1\u00a0months), respectively. Grade 3 neutropenia, radiation-induced esophagitis and radiodermatitis were observed in 5 (13.9%), 3 (8.3%) and 8 (22.2%) patients respectively. There were two treatment-related deaths due to esophageal perforation and hemorrhea.Conclusions: For those patients with upper esophageal carcinoma, IMRT combined with concurrent TP regimen chemotherapy was an effective treatment. However, more attention should be paid to the occurrence of perforation and hemorrhea. \u00a9 2013 Tu et al.; licensee BioMed Central Ltd.",
        "keywords": [
            "Cisplatin",
            "Intensity-modulated radiotherapy",
            "Paclitaxel",
            "Upper esophageal carcinoma"
        ],
        "venue": "Radiation Oncology",
        "year": 2013,
        "id": "vZ9yI2Yo"
    },
    "KziZb7zf": {
        "authors": [
            {
                "name": "Qiang Yan",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Jun Ni",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Guo-lei Zhang",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Xing Yao",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Wen-bin Yuan",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            }
        ],
        "title": "Efficacy of postoperative antiviral combined transcatheter arterial chemoembolization therapy in prevention of hepatitis B-related hepatocellular carcinoma recurrence",
        "abstract": "Background Recurrence of hepatitis B-related hepatocellular carcinoma (HCC) after curative resection is the leading factor influencing the prognosis of the disease. Therefore, further improvement of long-term survival may depend on the prevention and treatment of the recurrent tumor. The aim of this research was to investigate the role of antiviral therapy and postoperative transcatheter arterial chemoembolization (TACE) in the prevention and treatment of hepatitis B-related HCC recurrence. Methods One hundred and twenty patients who underwent curative resection of hepatitis B-related HCC between January 2005 and June 2008 at our hospital were enrolled. Patients were divided into four groups according to the post-operative adjuvant therapy they received, i.e., control, antiviral therapy group, TACE group, and combined group. The disease-free survival (DFS) and the 12-, 24-, 36-month cumulative recurrence rates were studied. Results There was no significant difference between isolated postoperative antiviral therapy group and control in terms of disease-free survival (P=0.283), while it was significantly higher in the TACE group compared to control (P=0.019). In all patients, however, viral prophylactic therapy combined with/without TACE brought a favorable result compared to those only with/without TACE (P <0.001). Similarly, no matter combined with or without antiviral treatment, postoperative TACE prolonged DFS (P=0.015). Naturally, a combination of viral prophylactic therapy on the baseline TACE significantly benefited patients' postoperative DFS (P=0.047) and vice verse (P=0.002). The 24-month cumulative recurrence rates of combined group were significantly lower than that of isolated control group and antiviral therapy (P <0.001 and P=0.011 respectively). However, 36-month recurrence rate was significantly different in the control group compared to the TACE group and combined group (P=0.040 and 0.002 respectively); same as the antiviral group compared to the combined group (P=0.034). Conclusions Post-operative TACE prevents early recurrence while antiviral therapy prevents late recurrence of HCC. Combination of antiviral therapy and TACE are suggested for prevention in HCC patients with high risk of recurrence.",
        "keywords": [
            "Antiviral therapy",
            "Disease-free survival",
            "Hepatocellular carcinoma",
            "Recurrence",
            "Transcatheter arterial chemoembolization"
        ],
        "venue": "Chinese Medical Journal",
        "year": 2013,
        "id": "KziZb7zf"
    },
    "OnRg2LaA": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "National Hepatobiliary and Enteric Surgery Research Centre"
            },
            {
                "name": "Jiantai He",
                "org": "National Hepatobiliary and Enteric Surgery Research Centre"
            },
            {
                "name": "Yangde Zhang",
                "org": "National Hepatobiliary and Enteric Surgery Research Centre"
            }
        ],
        "title": "MicroRNA-22 expression in hepatocellular carcinoma and its correlation with ezrin protein",
        "abstract": "Objective: Expression of microRNA-22 (miR-22) and ezrin protein (a membrane-cytoskeleton linking protein) in hepatocellular carcinoma (HCC) was investigated. Methods: Specimens of HCC and paracancerous tissue (control; ~5 cm away from tumour tissue) were collected from 192 patients. miR-22 expression was detected by real-time polymerase chain reaction; ezrin protein expression in tumour tissue was assessed immunohistochemically. Associations between miR-22 expression and clinicopathological features of HCC and ezrin expression were analysed. Results: miR-22 expression was lower in HCC tissue than in paracancerous tissue samples (median relative expression 0.676 versus 1.000 for control tissue). Expression of miR-22 was significantly associated with histological differentiation (relative expression 0.431 for lower grades of differentiation versus 0.918 for higher grades), and was associated with lymphatic metastasis (relative expression 0.518 if metastasis was present, 0.919 if absent). Survival time was shorter in patients with low miR-22 expression than in those with high expression (31.0\u00b12.6 versus 52.2\u00b15.1 months). There was a significant negative correlation between the expression of miR-22 and that of ezrin. Conclusions: miR-22 is downregulated in HCC and its expression is associated with the differentiation, metastasis and prognosis of the carcinoma. Ezrin is a potential regulatory protein of miR-22. \u00a9 The Author(s) 2013.",
        "keywords": [
            "clinicopathological features",
            "ezrin",
            "Hepatocellular carcinoma",
            "miR-22",
            "prognosis"
        ],
        "venue": "Journal of International Medical Research",
        "year": 2013,
        "id": "OnRg2LaA"
    },
    "hV2Ud4v6": {
        "authors": [
            {
                "name": "Zhiyun Zheng",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Sheng Gao",
                "org": ""
            },
            {
                "name": "Zhe Yang",
                "org": ""
            },
            {
                "name": "Jia Yao",
                "org": ""
            },
            {
                "name": "Shusen Zheng",
                "org": ""
            }
        ],
        "title": "Prognostic role of C-reactive protein in hepatocellular carcinoma: A systematic review and meta-analysis",
        "abstract": "Background: C-reactive protein (CRP) which used to be a prototypical inflammatory cytokine has been identified involving in the progression of tumor-promoting inflammation. Several studies have indicated that CRP is a predictor for hepatocellular carcinoma (HCC), but the results are controversial. Methods: We conducted a systematic review of ten studies (1885 patients) to examine the association of high serum CRP expression with overall survival (OS) and recurrence-free survival (RFS) in HCC patients by meta-analysis. Moreover, the correlation between high serum CRP and tumor clinicopathological parameters was also assessed. Hazard ratio (HR) or odds ratio (OR) with its 95% confidence interval (CI) was used as the effect size estimate. Results: Our pooled results showed that high expression level of serum CRP (\u226510 mg/L) was associated with poor OS (HR: 2.15, 95% CI: 1.76-2.63) and RFS (HR: 2.66, 95% CI: 1.54-4.58) in HCC. Serum CRP overexpression (\u226510 mg/L) was also significantly associated with the presence of tumor vascular invasion (OR: 3.05, 95% CI: 1.79-5.23), multiple tumor (OR: 2.36, 95% CI: 1.36-4.10), larger tumor size (OR: 3.41, 95% CI: 1.04-1 1.18), and advanced TNM stage (OR: 3.23, 95% CI: 2.29-4.57). In addition, serum CRP overexpression (\u226510 mg/L) tended to be correlated with poor differentiation (OR: 1.58, 95% CI: 0.74-3.39), though not significantly. Conclusion: The present systematic review and meta-analysis demonstrate that high serum level of CRP (\u2265 10 mg/L) denotes a poor prognosis of patients with HCC. \u00a9 Ivyspring International Publisher.",
        "keywords": [
            "C-reactive protein",
            "Hepatocellular carcinoma",
            "Prognosis",
            "Survival"
        ],
        "venue": "International Journal of Medical Sciences",
        "year": 2013,
        "id": "hV2Ud4v6"
    },
    "mzE9RdOl": {
        "authors": [
            {
                "name": "Zhenhua Hu",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Jie Zhou",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Haibo Wang",
                "org": "China Liver Transplant Registry"
            },
            {
                "name": "Min Zhang",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Shaogang Li",
                "org": "China Liver Transplant Registry"
            },
            {
                "name": "Yuzhou Huang",
                "org": "China Liver Transplant Registry"
            },
            {
                "name": "Jian Wu",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Zhiwei Li",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Shusen Zheng",
                "org": "Key Laboratory of Organ Transplantation"
            }
        ],
        "title": "Survival in Liver Transplant Recipients with Hepatitis B- or Hepatitis C-Associated Hepatocellular Carcinoma: The Chinese Experience from 1999 to 2010",
        "keywords": [
            ""
        ],
        "venue": "PLoS ONE",
        "year": 2013,
        "id": "mzE9RdOl"
    },
    "2p1RxD4A": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Department of Gastroenterology"
            },
            {
                "name": "Ruifeng Zhang",
                "org": "Department of Respiratory Medicine"
            },
            {
                "name": "Lianfeng Zhang",
                "org": "Department of Gastroenterology"
            },
            {
                "name": "Yuling Sun",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Weiyan Yao",
                "org": "Department of Gastroenterology"
            },
            {
                "name": "Ahong Zhao",
                "org": "Department of Pathology"
            },
            {
                "name": "Jiansheng Li",
                "org": "Department of Gastroenterology"
            },
            {
                "name": "Yaozong Yuan",
                "org": "Department of Gastroenterology"
            }
        ],
        "title": "Upregulation of transgelin is an independent factor predictive of poor prognosis in patients with advanced pancreatic cancer",
        "abstract": "Transgelin is a known actin-binding protein, which plays a role in regulating the functions of smooth muscle cells or fibroblasts. Recent evidence indicates that transgelin is involved in diverse human cancers, yet its role in pancreatic cancer remains unclear. We therefore evaluated the expression characteristics and function of transgelin in pancreatic cancer. Immunohistochemical analysis of benign (n\u00a0=\u00a030 patients) and malignant (n\u00a0=\u00a0114 patients) pancreatic ductal cells showed significantly higher transgelin staining in malignant cells. Lymph node metastasis (P\u00a0=\u00a00.026) and diabetes (P\u00a0=\u00a00.041) were shown to significantly correlate with transgelin protein expression. Patients with high transgelin expression showed a shorter 5-year overall survival and a lower tumor-specific survival than those with low transgelin expression. Multivariate analysis revealed that transgelin was an independent factor affecting pancreatic tumor-specific survival (P\u00a0=\u00a00.025). In vitro, RNA interference-mediated transgelin knockdown resulted in inhibition of pancreatic cancer cell proliferation, migration and invasion. Depletion of transgelin expression could suppress pancreatic tumorigenicity and tumor growth in vivo, and produce enhanced cytotoxic effects of gemcitabine on pancreatic cancer cells both in vitro and in vivo. Our results indicate that transgelin plays a promoting role in tumor progression, and appears to be a novel prognostic marker for advanced pancreatic cancer. \u00a9 2013 Japanese Cancer Association.",
        "keywords": [
            ""
        ],
        "venue": "Cancer Science",
        "year": 2013,
        "id": "2p1RxD4A"
    },
    "2RiR7Mgz": {
        "authors": [
            {
                "name": "Penghong Song",
                "org": "Key Laboratory of Combined Multi-organ Transplantation of Ministry of Public Health"
            },
            {
                "name": "Wenfeng Song",
                "org": "Key Laboratory of Combined Multi-organ Transplantation of Ministry of Public Health"
            },
            {
                "name": "Xiaosun Liu",
                "org": "Department of Surgery"
            },
            {
                "name": "Changhai Jin",
                "org": "Key Laboratory of Combined Multi-organ Transplantation of Ministry of Public Health"
            },
            {
                "name": "Haiyang Xie",
                "org": "Key Laboratory of Combined Multi-organ Transplantation of Ministry of Public Health"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Combined Multi-organ Transplantation of Ministry of Public Health"
            },
            {
                "name": "Biguang Tuo",
                "org": "Department of Gastroenterology"
            },
            {
                "name": "Shusen Zheng",
                "org": "Key Laboratory of Combined Multi-organ Transplantation of Ministry of Public Health"
            }
        ],
        "title": "Function and Expression of Cystic Fibrosis Transmembrane Conductance Regulator after Small Intestinal Transplantation in Mice",
        "abstract": "The secretion function of intestinal graft is one of the most important factors for successful intestinal transplantation. Cystic fibrosis transmembrane conductance regulator (CFTR) mediates HCO",
        "keywords": [
            ""
        ],
        "venue": "PLoS ONE",
        "year": 2013,
        "id": "2RiR7Mgz"
    },
    "T6HWzcxU": {
        "authors": [
            {
                "name": "Ruifeng Zhang",
                "org": "Department of Respiratory Medicine"
            },
            {
                "name": "Kejing Ying",
                "org": "Department of Respiratory Medicine"
            },
            {
                "name": "Liuhong Shi",
                "org": "Department of Respiratory Medicine"
            },
            {
                "name": "Lianfeng Zhang",
                "org": "Department of Gastroenterology"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Gastroenterology"
            }
        ],
        "title": "Combined endobronchial and endoscopic ultrasound-guided fine needle aspiration for mediastinal lymph node staging of lung cancer: A meta-analysis",
        "abstract": "Study objectives: This systematic review and meta-analysis was conducted to evaluate the accuracy of the combined endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) and endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) techniques and clarify its current role for the mediastinal lymph node staging of lung cancer. Methods: Medline, Web of Science, Elsevier and Ovid were searched to identify suitable studies up to 15th July 2012. Two investigators independently reviewed articles and extracted data. All EBUS-TBNA plus EUS-FNA studies for the mediastinal node staging of lung cancer were systematically reviewed. Sensitivity, specificity and other accuracy measures were pooled using random-effect models. Summary receiver operating characteristic curves were used to summarise overall test performance. Results: Eight studies met our inclusion criteria. The estimated summary measures for quantitative analysis of EBUS-TBNA plus EUS-FNA for mediastinal nodal staging of lung cancer were sensitivity, 0.86 (95% confidence interval [CI], 0.82-0.90); specificity, 1.00 (95% CI, 0.99-1.00); positive likelihood ratio, 51.77 (95% CI, 22.53-118.94); negative likelihood ratio, 0.15 (95% CI, 0.09-0.25); diagnostic odds ratio, 416.83 (95% CI, 140.08-1240.31); and area under the curve (AUC), 0.99. Conclusions: The current evidence suggests that the combined technique is more sensitive than EBUS-TBNA or EUS-FNA alone. The diagnostic power of this combined technique is accurate. As an almost completely minimally-invasive examination, EUS-FNA plus EBUS-TBNA may replace more invasive methods for evaluating mediastinal node staging of lung cancer. \u00a9 2013 Elsevier Ltd. All rights reserved.",
        "keywords": [
            "Endobronchial ultrasonography",
            "Endoscopic ultrasound-guided fine needle aspiration",
            "Lung cancer",
            "Transbronchial fine-needle aspiration"
        ],
        "venue": "European Journal of Cancer",
        "year": 2013,
        "id": "T6HWzcxU"
    },
    "wG0WCtQX": {
        "authors": [
            {
                "name": "Weilin Wang",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Qiang Sun",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Zehui Wu",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Dongkai Zhou",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Jianfeng Wei",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Haiyang Xie",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Shusen Zheng",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            }
        ],
        "title": "Mitochondrial dysfunction-related genes in hepatocellular carcinoma",
        "abstract": "Mitochondria dysfunction is associated with apoptotic resistance and metabolism of tumor cells. Hepatocellular carcinoma (HCC) is a complex and heterogeneous tumor with multiple genetic aberrations. Certain gene mutations in mitochondria may lead to mitochondrial dysfunction. The p53 family plays a key role in the mitochondrial apoptosis pathway and acts as part of the molecular mechanisms underlying mitochondrial dysfunction in HCC. The novel genes found in the mitochondrial apoptosis signaling pathways, such as mfn2, play a role in the p53 network. In mitochondrial metabolism, expression of certain genes may be associated with apoptosis when they are involved in hepatocarcinogenesis. MicroRNAs have also been found to play a role in this process. Some genes may even exhibit multiple functions in the mitochondrial dysfunction of HCC. In HCC therapy, genes have also been found to influence the chemotherapeutic treatment by killing cells via the apoptosis pathway or autophagy. Investigation of mitochondrial dysfunction-related genes could potentially provide evidence for novel therapies that target HCC.",
        "keywords": [
            "Gene",
            "Hepatocellular carcinoma",
            "Mitochondrial dysfunction",
            "Review"
        ],
        "venue": "Frontiers in Bioscience",
        "year": 2013,
        "id": "wG0WCtQX"
    },
    "VJCoejnu": {
        "authors": [
            {
                "name": "Jia Yao",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Xiao-Wen Feng",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Xiao-Bo Yu",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Hai-Yang Xie",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Li-Xian Zhu",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Zhe Yang",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Ba-Jin Wei",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            }
        ],
        "title": "Recipient IL-6-572c/G genotype is associated with reduced incidence of acute rejection following liver transplantation",
        "abstract": "Objective: Acute rejection resulting from alloimmune responses is a major risk factor affecting patient survival following liver transplantation. Since interleukin (IL)-6 can mediate acute rejection, the association between IL-6 gene single nucleotide polymorphisms (SNPs) and incidence of acute rejection in liver transplant recipients was investigated. Methods: Patients who received liver transplant between January 2005 and December 2010 were typed for IL6-572C/G (rs1800796) polymorphisms using the snapshot technique. Association between genotype and acute rejection was analysed using the SNP Statistics website:http://bioinfo.iconcologia.net/snpstats/start.htm. Allelic and genotypic distributions for rs1800796 were compared among 335 patients with or without acute rejection within the first 6 months following liver transplant. Results: Incidence of acute rejection was 11.94%. A heterozygous CG genotype for IL6-572C/G was associated with a lower acute rejection rate compared with homozygous CC or GG genotypes. Conclusion: IL6-572 CG genotype may be related to protection from acute rejection following liver transplant in Han Chinese patients. \u00a9 The Author(s) 2013.",
        "keywords": [
            "Acute rejection",
            "Il6-572c/g",
            "Interleukin-6 (il-6)",
            "Liver transplantation",
            "Rs1800796",
            "Single nucleotide polymorphism (snp)"
        ],
        "venue": "Journal of International Medical Research",
        "year": 2013,
        "id": "VJCoejnu"
    },
    "ugN8Dn2A": {
        "authors": [
            {
                "name": "Sheng-Zhang Lin",
                "org": "Department of Hepato-Biliary-Pancreatic Surgery"
            },
            {
                "name": "Kang-Jie Chen",
                "org": "Department of Hepato-Biliary-Pancreatic Surgery"
            },
            {
                "name": "Zhi-Yuan Xu",
                "org": "Department of Oncological Surgery"
            },
            {
                "name": "Hui Chen",
                "org": "Department of Hepato-Biliary-Pancreatic Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Hepato-Biliary-Pancreatic Surgery"
            },
            {
                "name": "Hai-Yang Xie",
                "org": "Department of Hepato-Biliary-Pancreatic Surgery"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Department of Hepato-Biliary-Pancreatic Surgery"
            }
        ],
        "title": "Prediction of recurrence and survival in hepatocellular carcinoma based on two cox models mainly determined by FoxP3",
        "abstract": "Hepatocellular carcinoma (HCC) is an aggressive disease with poor prognosis and limited methods to predict patient survival. Immune cells infiltrating tumors is known to impact clinical outcome. Here, we investigated the prognostic significance of immune infiltration within the tumor microenvironment in 245 specimens from two independent cohorts by immunohistochemical analyses. A Cox regression model was constructed using a training cohort and validated in an independent cohort. The diagnostic accuracy was evaluated by receiver operating characteristic curve. The activation, function, and chemotaxis of intratumoral regulatory T cells (Treg) were analyzed using flow cytometry, quantitative PCR, and chemotaxis assay. We identified that the proportion of FoxP3",
        "keywords": [
            ""
        ],
        "venue": "Cancer Prevention Research",
        "year": 2013,
        "id": "ugN8Dn2A"
    },
    "sOXMNtAY": {
        "authors": [
            {
                "name": "Sheng Gao",
                "org": ""
            },
            {
                "name": "Zhe Yang",
                "org": ""
            },
            {
                "name": "Zhiyun Zheng",
                "org": ""
            },
            {
                "name": "Jia Yao",
                "org": ""
            },
            {
                "name": "Min Deng",
                "org": ""
            },
            {
                "name": "Haiyang Xie",
                "org": ""
            },
            {
                "name": "Shusen Zheng",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            }
        ],
        "title": "Doxorubicin-eluting bead versus conventional TACE for unresectable hepatocellular carcinoma: A meta-analysis",
        "abstract": "Background/Aims: Doxorubicin-eluting bead TACE (DEB-TACE) has recently been developed as a novel therapy option for HCC. However, the clinical efficacy of DEB-TACE is still unclear. Herein, we performed a meta-analysis to evaluate the efficacy of DEB-TACE compared with conventional TACE (cTACE). Methodology: We inlcuded seven studies (a total of 693 patients) to compare DEB-TACE with cTACE. The pooled odds ratios (OR) were calculated using a random or fixed effects model. MEDLINE, EMBASE and the Cochrane Database were searched for articles published from dates of inceptions up to February 20, 2012. Sensitivity analysis and publication bias estimate were also performed to evaluate the potential risk bias in the overall results of pooled analysis. Results: The pooled estimates for tumor response of DEB-TACE were not significantly different from those of cTACE, with CR (OR: 1.18; 95%CI: 0.81-1.71; p=0.394), PR (OR: 1.37; 95%CI: 0.94-1.99; p=0.101), SD (OR: 0.88; 95%CI: 0.51-1.51; p=0.637), PD (OR: 0.85; 95%CI: 0.52-1.38; p=0.512), DC (OR: 1.37, 95%CI: 0.95-1.98; p=0.089) and OR (OR: 1.40; 95%CI: 0.97-2.000; p=0.070). Conclusions: The current evidence suggests that DEB-TACE is able to accomplish the same tumor response as cTACE. Although this analysis provides a comprehensive look at published data involving the clinical efficacy of DEB-TACE compared with conventional TACE, additional large scale of randomized-control studies are still needed. \u00a9 H.G.E. Update Medical Publishing S.A.",
        "keywords": [
            "Conventional TACE",
            "Doxorubicin-eluting bead TACE",
            "Unresectable hepatocellular carcinoma"
        ],
        "venue": "Hepato-Gastroenterology",
        "year": 2013,
        "id": "sOXMNtAY"
    },
    "4VCJPQqV": {
        "authors": [
            {
                "name": "Sunyi Ye",
                "org": ""
            },
            {
                "name": "Jian Wu",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Zhen Lv",
                "org": ""
            },
            {
                "name": "Haiyang Xie",
                "org": ""
            },
            {
                "name": "Shusen Zheng",
                "org": ""
            }
        ],
        "title": "Interleukin-35: The Future of Hyperimmune-Related Diseases?",
        "keywords": [
            ""
        ],
        "venue": "Journal of Interferon and Cytokine Research",
        "year": 2013,
        "id": "4VCJPQqV"
    },
    "3szCiB5U": {
        "authors": [
            {
                "name": "Yu-Ling Sun",
                "org": "Institute of Hepatobiliary and Pancreatic Diseases"
            },
            {
                "name": "Yang Fu",
                "org": "Institute of Hepatobiliary and Pancreatic Diseases"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Digestive Medicine, First Affliated Hospital"
            },
            {
                "name": "Xiu-Xian Ma",
                "org": "Institute of Hepatobiliary and Pancreatic Diseases"
            },
            {
                "name": "Zhi-Wei Wang",
                "org": "Department of Radiological Intervention, First Affliated Hospital"
            },
            {
                "name": "Yan Wu",
                "org": "Department of Radiology, First Affliated Hospital"
            }
        ],
        "title": "Staged management of Budd-Chiari syndrome caused by co-obstruction of the inferior vena cava and main hepatic veins",
        "abstract": "BACKGROUND: Collateralized intra- and extra-hepatic routes in patients with Budd-Chiari syndrome (BCS) were important. This study aimed to investigate the feasibility and clinical outcomes of the staged management of BCS based on the degree of compensation provided by intra- or extra-hepatic collateral circulations. METHODS: A total of 103 adult patients with BCS caused by co-obstruction of the inferior vena cava (IVC) and main hepatic veins (MHVs) between March 2001 and October 2009 were enrolled in this study. Based on the pathological classification and degree of hemodynamic compensation by collateral circulations, treatment priority for IVC hypertension was determined in the first-stage treatment. Patients were deemed eligible for second-stage treatment when the first-stage treatment failed to relieve. RESULTS: Imaging results revealed that most patients had collateral circulations to different extents. Based on the degree of compensation provided by these collateral circulations, 74 patients underwent single-stage treatment for IVC hypertension, i.e., radiologic intervention (RI) for 61 patients and surgical procedures (SPs) for 13. One patient was treated for portal hypertension. Twenty-nine patients underwent second-stage treatment (25 underwent RI and SP, and 4 only SP). The general morbidity and mortality after all procedures were 8.3% and 1.5%, respectively. After a median follow-up of 35 months, 4 patients underwent second-stage treatment and 7 underwent recanalization of the IVC/MHVs. Two patients died of hepatocellular carcinoma and 1 died of graft obstruction. CONCLUSION: Staged management produces excellent outcomes for patients with BCS caused by co-obstruction of the IVC and MHVs. \u00a9 2013, Hepatobiliary Pancreat Dis Int. All rights reserved.",
        "keywords": [
            "Budd-Chiari syndrome",
            "Collateral circulation",
            "Hemodynamics",
            "Portal hypertension"
        ],
        "venue": "Hepatobiliary and Pancreatic Diseases International",
        "year": 2013,
        "id": "3szCiB5U"
    },
    "XJvb2eHM": {
        "authors": [
            {
                "name": "Zhi-Jun Jiang",
                "org": "Division of Hepatobiliary Pancreatic Surgery"
            },
            {
                "name": "Ying Chen",
                "org": "Division of Hepatobiliary Pancreatic Surgery"
            },
            {
                "name": "Wei-Lin Wang",
                "org": "Division of Hepatobiliary Pancreatic Surgery"
            },
            {
                "name": "Yan Shen",
                "org": "Division of Hepatobiliary Pancreatic Surgery"
            },
            {
                "name": "Min Zhang",
                "org": "Division of Hepatobiliary Pancreatic Surgery"
            },
            {
                "name": "Hai-Yang Xie",
                "org": "Division of Hepatobiliary Pancreatic Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "Division of Hepatobiliary Pancreatic Surgery"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Division of Hepatobiliary Pancreatic Surgery"
            }
        ],
        "title": "Management hepatolithiasis with operative choledochoscopic FREDDY laser lithotripsy combined with or without hepatectomy",
        "abstract": "BACKGROUND: Hepatolithiasis is very common in East Asia. It is benign in nature, but has a high recurrence rate. It is likely to lead to biliary cirrhosis and increase the risk of cholangiocarcinoma. Hence, the treatment of hepatolithiasis is diffcult but vital. In this report, we present a novel approach to manage hepatolithiasis using the choledochoscopic Frequency-Doubled Double pulse Nd:YAG (FREDDY) laser lithotripsy combined with or without hepatectomy. METHODS: Between July 2009 and October 2012, 45 patients underwent choledochoscopic FREDDY laser lithotripsy combined with or without hepatectomy (laser lithotripsy group). Forty-eight patients underwent a traditional operation (traditional method group) from January 2009 to June 2009. Comparative analysis was made of demographic and clinical characteristics of the two groups. RESULTS: The final stone clearance rate of the laser lithotripsy group was 93.3%, whereas that of the traditional method group was 85.4% (P=0.22). In the laser lithotripsy group, 2 patients experienced hemobilia and 3 patients had acute cholangitis. In the traditional method group, 3 patients had intraoperative hemorrhage, 1 patient had bile leakage, 6 patients had acute cholangitis, and 1 patient died of liver failure. Moreover, the operative time in the traditional method group was signifcantly longer than that in the laser lithotripsy group (P=0.01). The mean hospital stay of the patients in the traditional method group was longer than that in the laser lithotripsy group (9.8 vs 8.2 days, P=0.17). Recurrent intrahepatic bile duct stones were not found during the follow-up period in the two groups. CONCLUSION: Operative choledochoscopic FREDDY laser lithotripsy combined with or without hepatectomy may be an effective and safe treatment for hepatolithiasis. \u00a9 2013, Hepatobiliary Pancreat Dis Int. All rights reserved.",
        "keywords": [
            "Choledochoscopy",
            "Frequency-doubled double pulse Nd:YAG laser",
            "Hepatectomy",
            "Hepatolithiasis",
            "Lithotripsy"
        ],
        "venue": "Hepatobiliary and Pancreatic Diseases International",
        "year": 2013,
        "id": "XJvb2eHM"
    },
    "dkk9jAiG": {
        "authors": [
            {
                "name": "Junliang Fu",
                "org": "Institute of Translational Hepatology"
            },
            {
                "name": "Zheng Zhang",
                "org": "Institute of Translational Hepatology"
            },
            {
                "name": "Lin Zhou",
                "org": "Interventional Department of Radiology"
            },
            {
                "name": "Zhaorui Qi",
                "org": "Department of Surgery"
            },
            {
                "name": "Shaojun Xing",
                "org": "Institute of Translational Hepatology"
            },
            {
                "name": "Jiyun Lv",
                "org": "Institute of Translational Hepatology"
            },
            {
                "name": "Jianfei Shi",
                "org": "Institute of Translational Hepatology"
            },
            {
                "name": "Baoyun Fu",
                "org": "Institute of Translational Hepatology"
            },
            {
                "name": "Zhenwen Liu",
                "org": "Department of Surgery"
            },
            {
                "name": "Ji-Yuan Zhang",
                "org": "Institute of Translational Hepatology"
            },
            {
                "name": "Lei Jin",
                "org": "Institute of Translational Hepatology"
            },
            {
                "name": "Yulai Zhao",
                "org": "Department of Pathology and Hepatology"
            },
            {
                "name": "George K.K Lau",
                "org": "Institute of Translational Hepatology"
            },
            {
                "name": "Jingmin Zhao",
                "org": "Department of Pathology and Hepatology"
            },
            {
                "name": "Fu-Sheng Wang",
                "org": "Institute of Translational Hepatology"
            }
        ],
        "title": "Impairment of CD4+ cytotoxic T cells predicts poor survival and high recurrence rates in patients with hepatocellular carcinoma",
        "abstract": "The role of CD4",
        "keywords": [
            ""
        ],
        "venue": "Hepatology",
        "year": 2013,
        "id": "dkk9jAiG"
    },
    "kF3kITUd": {
        "authors": [
            {
                "name": "Yukai Liu",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Ken Chen",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Xun Kou",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Yu Han",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Lin Zhou",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Chunyu Zeng",
                "org": "Chongqing Institute of Cardiology"
            }
        ],
        "title": "Aliskiren and Amlodipine in the Management of Essential Hypertension: Meta-Analysis of Randomized Controlled Trials",
        "abstract": "Background:Aliskiren is a novel renin-angiotensin aldosterone system (RAAS) inhibitor, the combination therapy of aliskiren and amlodipine for blood pressure control have been reported recently. The primary objective of this analysis is to review recently reported randomized controlled trials (RCTs) to compare antihypertensive effects and adverse events between mono (amlodipine or aliskiren alone) and combination therapy of both medicines.Methods:Databases for the search included Pubmed, Embase and the Cochrane Central Register of Controlled Trials. Revman v5.0 statistical program was used to analyze the data. Weighted mean differences (WMD) with a 95% confidence interval (CI) were used for the calculation of continuous data, and relative risk (RR) with a 95% CI was used for dichotomous data.Results:We analyzed the data from 7 RCTs for a total of 6074 participants in this meta-analysis. We found that the aliskiren/amlodipine combination therapy had a stronger effect in lowering blood pressure as compared with the monotherapy using aliskiren (SBP: WMD = -10.42, 95% CI -13.03\u223c-7.82, P<0.00001; DBP: WMD = -6.60, 95% CI -7.22\u223c-5.97, P<0.00001) or amlodipine (SBP: WMD = -4.85, 95% CI -6.88\u223c-2.81, P<0.00001; DBP: WMD = -2.91, 95% CI -3.85\u223c-1.97, P<0.00001). No differences were found in terms of adverse events between combination therapy and monotherapy, except for the rates of peripheral edema and hypokalaemia which were significantly lower in the combination therapy than in the amlodipine monotherapy (RR = 0.78, 0.66\u223c0.92, P = 0.004; RR = 0.51, 0.27\u223c0.97, P = 0.04). Similar antihypertensive effects were found in both obese (body mass index > = 30 kg/m",
        "keywords": [
            ""
        ],
        "venue": "PLoS ONE",
        "year": 2013,
        "id": "kF3kITUd"
    },
    "U4HkK8fk": {
        "authors": [
            {
                "name": "Chun Wang",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Yong-Mei Liu",
                "org": ""
            },
            {
                "name": "Zhen-Yu Ding",
                "org": ""
            }
        ],
        "title": "Comparison of platinum-containing doublet chemotherapy and liposome paclitaxel monotherapy for the treatment of elderly patients with advanced non-small cell lung cancer",
        "keywords": [
            "Chemotherapy",
            "Elderly patients",
            "Non-small cell lung cancer"
        ],
        "venue": "Journal of Sichuan University (Medical Science Edition)",
        "year": 2013,
        "id": "U4HkK8fk"
    },
    "qfeDB1HL": {
        "authors": [
            {
                "name": "Songming Ding",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Wu Zhang",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Zhiyuan Xu",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Chunyang Xing",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Haiyang Xie",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Haijun Guo",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Kanjie Chen",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Penghong Song",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Yu Gu",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Fengqiang Xiao",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Shusen Zheng",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            }
        ],
        "title": "Induction of an EMT-like transformation and MET in vitro",
        "abstract": "Background: The epithelial-to-mesenchymal transition (EMT) and mesenchymal-to-epithelial transition (MET) play pivotal roles in metastasis of epithelial cancers. The distinction between them has shed new light on the molecular mechanisms of tumor metastasis. Recently, tumor microenvironment (TM) has been identified as one of the most potent inducers of EMT and MET. TM is characterized by its complexity and flexibility. The purpose of this study was to ascertain the exact effect of each distinct TM component on the evolution hepatocellular carcinoma (HCC) metastasis.Methods: Two different cell culture models were used. The HCC cell line Bel-7402 was co-cultured with the normal liver cell line HL-7702 or with the retinal vascular endothelial cell line RF/6A in double-layer six-well plates, imitating the direct interaction between tumor-host cells and tumor cells. Bel-7402 was also cultured in the conditioned medium (CM) of the human lung fibroblast cell line MRC-5, HL-7702 or RF/6A, imitating an indirect interaction. Integrin \u03b21, \u03b23, \u03b24, \u03b27, laminin \u03b23, E-cadherin and Snail levels were measured by quantitative RT-PCR in tumor sepecimens from 42 resected HCC. Results: We found that Bel-7402 cells co-cultured with HL-7702 or RF/6A cells were induced to undergo MET. The expression of E-cadherin, \u03b1-catenin and \u03b2-catenin was up-regulated, accompanied with a strengthened E-cadherin/catenin complex on the membrane of co-cultured Bel-7402 cells. Consequently, the invasion and migration ability of cells was declined. Conversely, Bel-7402 cells cultured in conditioned medium from MRC-5 cells underwent an EMT-like transformation as the cells became elongated with increased invasion and migration ability. Furthermore, we demonstrated that HL-7702 cells could generally inhibit the tumorigenicity and viability of Bel-7402 cells. We also found that integrin \u03b21 expression was negatively associated with capsular formation, and that integrin \u03b24 expression was negatively associated with CK19 expression. Conclusion: Our findings highlight the strong influences exerted by TM on tumor progression through EMT and MET by impacting the expression of adhesion molecules, including the E-cadherin/catenin complex, laminins and integrins. \u00a9 2013 Ding et al.; licensee BioMed Central Ltd.",
        "keywords": [
            "Co-culture",
            "Conditioned medium culture",
            "EMT",
            "MET",
            "Tumor microenvironment"
        ],
        "venue": "Journal of Translational Medicine",
        "year": 2013,
        "id": "qfeDB1HL"
    },
    "66WVKlHy": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Department of Laboratory Medicine"
            },
            {
                "name": "Lijuan Sun",
                "org": "Hubei Province Key Laboratory of Biotechnology of TCM"
            },
            {
                "name": "Hongkun Wu",
                "org": "Department of Laboratory Medicine"
            },
            {
                "name": "Lingzhen Zhang",
                "org": "Department of Laboratory Medicine"
            },
            {
                "name": "Mingcang Chen",
                "org": "Shanghai Key Laboratory of Chemical Biology"
            },
            {
                "name": "Jianwen Liu",
                "org": "Shanghai Key Laboratory of Chemical Biology"
            },
            {
                "name": "Renqian Zhong",
                "org": "Department of Laboratory Medicine"
            }
        ],
        "title": "Oridonin ameliorates lupus-like symptoms of MRLlpr/lpr mice by inhibition of B-cell activating factor (BAFF)",
        "abstract": "Oridonin, a pharmacologically safe agent extracted from Isodon Serra, has been shown to possess potent anti-inflammatory properties. However, it is not clear whether Oridonin affects B-cell activating factor (BAFF) expression, thereby exerting beneficial effects in the treatment of BAFF-associated autoimmune diseases such as systemic lupus erythematosus (SLE). Thus, the current study aimed to find the function of Oridonin in regulation of BAFF and amelioration of SLE. In vitro, we explored the effect of Oridonin on BAFF expression and production in mouse macrophages. Moreover, using a spontaneous murine SLE model, we investigated the role of Oridonin delivery in the treatment of lupus-like disease in MRL",
        "keywords": [
            "B cell",
            "BAFF",
            "Isodon Serra",
            "MRL lpr/lpr mice",
            "Oridonin",
            "Systemic lupus erythematosus"
        ],
        "venue": "European Journal of Pharmacology",
        "year": 2013,
        "id": "66WVKlHy"
    },
    "D9sFmoPN": {
        "authors": [
            {
                "name": "Jin Cai",
                "org": "Department of Cardiology"
            },
            {
                "name": "Yu Han",
                "org": "Department of Cardiology"
            },
            {
                "name": "Hongmei Ren",
                "org": "Department of Cardiology"
            },
            {
                "name": "Caiyu Chen",
                "org": "Department of Cardiology"
            },
            {
                "name": "Duofen He",
                "org": "Department of Cardiology"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Cardiology"
            },
            {
                "name": "Gilbert M. Eisner",
                "org": "Internal Medicine"
            },
            {
                "name": "Laureano D. Asico",
                "org": "Division of Nephrology"
            },
            {
                "name": "Pedro A. Jose",
                "org": "Division of Nephrology"
            },
            {
                "name": "Chunyu Zeng",
                "org": "Department of Cardiology"
            }
        ],
        "title": "Extracellular vesicle-mediated transfer of donor genomic DNA to recipient cells is a novel mechanism for genetic influence between cells",
        "abstract": "Extracellular vesicles (EVs) carry signals within or at their limiting membranes, providing a mechanism by which cells can exchange more complex information than what was previously thought. In addition to mRNAs and microRNAs, there are DNA fragments in EVs. Solexa sequencing indicated the presence of at least 16434 genomic DNA (gDNA) fragments in the EVs from human plasma. Immunofluorescence study showed direct evidence that acridine orange-stained EV DNAs could be transferred into the cells and localize to and inside the nuclear membrane. However, whether the transferred EV DNAs are functional or not is not clear. We found that EV gDNAs could be homologously or heterologously transferred from donor cells to recipient cells, and increase gDNA-coding mRNA, protein expression, and function (e.g. AT",
        "keywords": [
            "AT1 receptor",
            "BCR/ABL hybrid gene",
            "extracellular vesicles",
            "genomic DNA"
        ],
        "venue": "Journal of Molecular Cell Biology",
        "year": 2013,
        "id": "D9sFmoPN"
    },
    "FMPvPa52": {
        "authors": [
            {
                "name": "Fenqiang Xiao",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Wu zhang",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Liming Chen",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Fei Chen",
                "org": "Institution of Cardiology"
            },
            {
                "name": "Haiyang Xie",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Chunyang Xing",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Xiaobo Yu",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Songming Ding",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Kangjie Chen",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Haijun Guo",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Jun Cheng",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Shusen Zheng",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            }
        ],
        "title": "MicroRNA-503 inhibits the G1/S transition by downregulating cyclin D3 and E2F3 in hepatocellular carcinoma",
        "abstract": "Background: Increasing evidence indicates that deregulation of microRNAs (miRNAs) is involved in tumorigenesis. Downregulation of microRNA-503 has been observed in various types of diseases, including cancer. However, the biological function of miR-503 in hepatocellular carcinoma (HCC) is still largely unknown. In this study we aimed to elucidate the prognostic implications of miR-503 in HCC and its pathophysiologic role.Methods: Quantitative reverse transcriptase polymerase chain reaction was used to evaluate miR-503 expression in HCC tissues and cell lines. Western blotting was performed to evaluate the expression of the miR-503 target genes. In vivo and in vitro assays were performed to evaluate the function of miR-503 in HCC. Luciferase reporter assay was employed to validate the miR-503 target genes.Results: miR-503 was frequently downregulated in HCC cell lines and tissues. Low expression levels of miR-503 were associated with enhanced malignant potential such as portal vein tumor thrombi, histologic grade, TNM stage, AFP level and poor prognosis. Multivariate analysis indicated that miR-503 downregulation was significantly associated with worse overall survival of HCC patients. Functional studies showed miR-503 suppressed the proliferation of HCC cells by induction of G1 phase arrest through Rb-E2F signaling pathways, and thus may function as a tumor suppressor. Further investigation characterized two cell cycle-related molecules, cyclin D3 and E2F3, as the direct miR-503 targets.Conclusion: Our data highlight an important role for miR-503 in cell cycle regulation and in the molecular etiology of HCC, and implicate the potential application of miR-503 in prognosis prediction and miRNA-based HCC therapy. \u00a9 2013 Xiao et al.; licensee BioMed Central Ltd.",
        "keywords": [
            "Cyclin D3",
            "E2F3",
            "G1/S transition",
            "Hepatocellular carcinoma",
            "microRNA-503",
            "Overall survival"
        ],
        "venue": "Journal of Translational Medicine",
        "year": 2013,
        "id": "FMPvPa52"
    },
    "eKvlddwf": {
        "authors": [
            {
                "name": "Lu Li",
                "org": ""
            },
            {
                "name": "Qing Li",
                "org": ""
            },
            {
                "name": "Yong Xu",
                "org": ""
            },
            {
                "name": "Meijuan Huang",
                "org": ""
            },
            {
                "name": "Yongmei Liu",
                "org": ""
            },
            {
                "name": "Youling Gong",
                "org": ""
            },
            {
                "name": "Feng Peng",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Zhenyu Ding",
                "org": ""
            },
            {
                "name": "Li Ren",
                "org": ""
            },
            {
                "name": "Jin Wang",
                "org": ""
            },
            {
                "name": "You Lu",
                "org": ""
            },
            {
                "name": "Jiang Zhu",
                "org": ""
            },
            {
                "name": "Mei Hou",
                "org": ""
            }
        ],
        "title": "Phase II study of oral etoposide maintenance for patients with extensive stage small cell lung cancer who have responded to the induction on an EP regimen",
        "abstract": "Background: Maintenance therapy for extensive stage small cell lung cancer (ES-SCLC) is still under debate. Many new agents fail during the maintenance course. As an active agent for SCLC, oral etoposide is worth being re-evaluated. Methods: This phase II study was performed to evaluate the toxicity/efficacy of the maintenance of patients with oral etoposide with ES-SCLC responding (complete remission [CR] + partial remission [PR]) to the induction of four cycles of etoposide plus cisplatin (EP) chemotherapy. Maintenance therapy with oral etoposide (50mg/m",
        "keywords": [
            "Extensive stage",
            "Maintenance",
            "Oral etoposide",
            "Small cell lung cancer"
        ],
        "venue": "Thoracic Cancer",
        "year": 2013,
        "id": "eKvlddwf"
    },
    "Pun07e0x": {
        "authors": [
            {
                "name": "Yafang Wang",
                "org": ""
            },
            {
                "name": "Lili Liu",
                "org": ""
            },
            {
                "name": "Xiangqiang Liu",
                "org": ""
            },
            {
                "name": "Hui Zhang",
                "org": ""
            },
            {
                "name": "Jiaming Liu",
                "org": ""
            },
            {
                "name": "Bin Feng",
                "org": ""
            },
            {
                "name": "Yulong Shang",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Kaichun Wu",
                "org": ""
            },
            {
                "name": "Yongzhan Nie",
                "org": ""
            },
            {
                "name": "Hongbo Zhang",
                "org": ""
            },
            {
                "name": "Daiming Fan",
                "org": ""
            }
        ],
        "title": "Shugoshin1 enhances multidrug resistance of gastric cancer cells by regulating MRP1, Bcl-2, and Bax genes",
        "abstract": "Multidrug resistance (MDR) is a major clinical obstacle in treatment of gastric cancer (GC) and it accounts for the majority of cancer-related mortalities. Shugoshin1 (SGO1) is an important player in appropriate chromosome segregation and is involved in tumorigenesis. In this study, we found endogenous SGO1 overexpression in the multidrug-resistant GC cell lines SGC7901/VCR and SGC7901/ADR compared with their parental cell line SGC7901. By enhancing expression of SGO1, sensitivity of SGC7901 cells to vincristine (VCR), adriamycin, 5-fluorouracil (5-FU), and cisplatin (CDDP) was significantly diminished. Silencing its expression resulted in enhanced sensitivity of SGC7901/VCR and SGC7901/ADR cells to these antitumor drugs. Additionally, we confirmed that SGO1 increased capacity of cells to enable adriamycin (ADR) efflux and inhibit drug-induced apoptosis by regulating MRP 1, Bcl-2, and Bax genes so as to confer a MDR phenotype to GC cells. In brief, these findings suggest that SGO1 promotes MDR of GC cells and may be useful as a novel therapeutic target for preventing or reversing MDR. \u00a9 2013 International Society of Oncology and BioMarkers (ISOBM).",
        "keywords": [
            "Gastric cancer",
            "Lentivirus vector",
            "Multidrug resistance",
            "SGO1"
        ],
        "venue": "Tumor Biology",
        "year": 2013,
        "id": "Pun07e0x"
    },
    "B97DdV9r": {
        "authors": [
            {
                "name": "Liang Sun",
                "org": "Key Laboratory of Geriatrics"
            },
            {
                "name": "Cai-you Hu",
                "org": "Department of Neurology"
            },
            {
                "name": "Xiao-hong Shi",
                "org": "Key Laboratory of Geriatrics"
            },
            {
                "name": "Chen-guang Zheng",
                "org": "Department of Cardiothoracic Surgery"
            },
            {
                "name": "Ze-zhi Huang",
                "org": "Yongfu Committee of the Chinese People's Political Consultative Conference"
            },
            {
                "name": "Ze-ping Lv",
                "org": "Department of Neurology"
            },
            {
                "name": "Jin Huang",
                "org": "Key Laboratory of Geriatrics"
            },
            {
                "name": "Gang Wan",
                "org": "Key Laboratory of Geriatrics"
            },
            {
                "name": "Ke-yan Qi",
                "org": "Key Laboratory of Geriatrics"
            },
            {
                "name": "Si-ying Liang",
                "org": "Key Laboratory of Geriatrics"
            },
            {
                "name": "Lin Zhou",
                "org": "Beijing Youth Science and Technology Club"
            },
            {
                "name": "Ze Yang",
                "org": "Key Laboratory of Geriatrics"
            }
        ],
        "title": "Trans-Ethnical Shift of the Risk Genotype in the CETP I405V with Longevity: A Chinese Case-Control Study and Meta-Analysis",
        "abstract": "Background:The I405V polymorphism of the cholesteryl ester transfer protein gene (CETP) has been suggested to be a protective factor conferring longevity in Ashkenazi Jews, although findings in other races are not supportive. This paper describes a case-control study and a meta-analysis conducted to derive a more precise estimation of the association between CETP 405V and longevity.Methods:We enrolled 1,021 ethnic Han Chinese participants (506 in the longevity group and 515 controls), then performed a meta-analysis that integrated the current study and previously published ones. Pooled odds ratios (OR) were calculated for allele contrasts, dominant and recessive inheritance models to assess the association between CETP 405V and longevity according to the ethnic stratification.Results:Our case-control data indicated that CETP 405V is a longevity risk allele in all genetic models (P",
        "keywords": [
            ""
        ],
        "venue": "PLoS ONE",
        "year": 2013,
        "id": "B97DdV9r"
    },
    "8SFOtjQu": {
        "authors": [
            {
                "name": "Bin Chen",
                "org": "Shanghai Institute of Immunology"
            },
            {
                "name": "Duo Zhang",
                "org": "Department of Otolaryngology, Eye Ear Nose and Throat Hospital"
            },
            {
                "name": "Jian Zhou",
                "org": "Department of Otolaryngology, Eye Ear Nose and Throat Hospital"
            },
            {
                "name": "Qing Li",
                "org": "Shanghai Institute of Immunology"
            },
            {
                "name": "Lin Zhou",
                "org": "Shanghai Institute of Immunology"
            },
            {
                "name": "Shi-Min Li",
                "org": "Department of Pathology, Eye Ear Nose and Throat Hospital"
            },
            {
                "name": "Li Zhu",
                "org": "Department of Pathology, Eye Ear Nose and Throat Hospital"
            },
            {
                "name": "Kuang-Yen Chou",
                "org": "Shanghai Institute of Immunology"
            },
            {
                "name": "Liang Zhou",
                "org": "Department of Otolaryngology, Eye Ear Nose and Throat Hospital"
            },
            {
                "name": "Lei Tao",
                "org": "Department of Otolaryngology, Eye Ear Nose and Throat Hospital"
            },
            {
                "name": "Li-Ming Lu",
                "org": "Shanghai Institute of Immunology"
            }
        ],
        "title": "High CCR6/CCR7 expression and Foxp3+ Treg cell number are positively related to the progression of laryngeal squamous cell carcinoma",
        "keywords": [
            "CCR6",
            "CCR7",
            "Forkhead box P3",
            "Laryngeal squamous cell carcinoma",
            "Regulatory T cell"
        ],
        "venue": "Oncology Reports",
        "year": 2013,
        "id": "8SFOtjQu"
    },
    "wcpzy7ld": {
        "authors": [
            {
                "name": "Zhigang Ren",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Xinhua Chen",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Guangying Cui",
                "org": "State Key Laboratory for Diagnosis and Treatment of Infectious Disease"
            },
            {
                "name": "Shengyong Yin",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Luyan Chen",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Jianwen Jiang",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Zhenhua Hu",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Haiyang Xie",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Shusen Zheng",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            }
        ],
        "title": "Nanosecond Pulsed Electric Field Inhibits Cancer Growth Followed by Alteration in Expressions of NF-\u03baB and Wnt/\u03b2-Catenin Signaling Molecules",
        "abstract": "Cancer remains a leading cause of death worldwide and total number of cases globally is increasing. Novel treatment strategies are therefore desperately required for radical treatment of cancers and long survival of patients. A new technology using high pulsed electric field has emerged from military application into biology and medicine by applying nsPEF as a means to inhibit cancer. However, molecular mechanisms of nsPEF on tumors or cancers are still unclear. In this paper, we found that nsPEF had extensive biological effects in cancers, and clarified its possible molecular mechanisms in vitro and in vivo. It could not only induce cell apoptosis via dependent-mitochondria intrinsic apoptosis pathway that was triggered by imbalance of anti- or pro-apoptosis Bcl-2 family proteins, but also inhibit cell proliferation through repressing NF-\u03baB signaling pathway to reduce expressions of cyclin proteins. Moreover, nsPEF could also inactivate metastasis and invasion in cancer cells by suppressing Wnt/\u03b2-Catenin signaling pathway to down-regulating expressions of VEGF and MMPs family proteins. More importantly, nsPEF could function safely and effectively as an anti-cancer therapy through inducing tumor cell apoptosis, destroying tumor microenvironment, and depressing angiogenesis in tumor tissue in vivo. These findings may provide a creative and effective therapeutic strategy for cancers. \u00a9 2013 Ren et al.",
        "keywords": [
            ""
        ],
        "venue": "PLoS ONE",
        "year": 2013,
        "id": "wcpzy7ld"
    },
    "X4YodUXP": {
        "authors": [
            {
                "name": "Sheng Yan",
                "org": ""
            },
            {
                "name": "Fei Sun",
                "org": ""
            },
            {
                "name": "Zhiwei Li",
                "org": ""
            },
            {
                "name": "Jie Xiang",
                "org": ""
            },
            {
                "name": "Yuan Ding",
                "org": ""
            },
            {
                "name": "Zhongjie Lu",
                "org": ""
            },
            {
                "name": "Yang Tian",
                "org": ""
            },
            {
                "name": "Hui Chen",
                "org": ""
            },
            {
                "name": "Jinhua Zhang",
                "org": ""
            },
            {
                "name": "Yan Wang",
                "org": ""
            },
            {
                "name": "Penghong Song",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Shusen Zheng",
                "org": ""
            }
        ],
        "title": "Reduction of intestinal electrogenic glucose absorption after duodenojejunal bypass in a mouse model",
        "abstract": "Background: The role of intestinal glucose absorption in reducing glycemic levels after duodenojejunal bypass (DJB) is unclear. We hypothesized that DJB surgery decreases intestinal electrogenic glucose absorption by sodium glucose co-transporter 1 (SGLT1), leading to decreased glucose absorption and reduced blood glucose. Six groups of C57/BL6 mice were studied (n = 6 each) 2 weeks, 1 month, and 2 months after DJB or sham surgery. Methods: Daily weight and food intake were measured for 1 month and an oral glucose tolerance test was performed 2 months after surgery. Electrogenic glucose absorption was quantified in an Ussing chamber according to the sodium-dependent increase of short-circuit current (Isc). Intestinal morphology was assessed by hematoxylin and eosin staining. Expression of SGLT1 was determined by quantitative PCR and Western blotting. Results: The DJB mice lost weight compared with the sham group and exhibited significant adaptive changes, with increased villus height, crypt depth, and villus surface area. Oral glucose absorption was significantly reduced in the DJB mice compared with the sham group. Glucose-induced Isc was significantly lower in the DJB mice than in the sham mice 1 and 2 months after surgery, indicating that SGLT1 activity was reduced after DJB. Transcript levels and protein abundance of SGLT1 after DJB were also decreased compared with the sham group. Conclusions: DJB surgery reduced intestinal glucose absorption by reducing the activity and expression of the glucose transporter SGLT1, which represents a potential therapeutic target for patients with diabetes. \u00a9 2013 Springer Science+Business Media New York.",
        "keywords": [
            "Bariatric surgery",
            "Duodenojejunal bypass",
            "Glucose absorption",
            "SGLT1",
            "Ussing chamber"
        ],
        "venue": "Obesity Surgery",
        "year": 2013,
        "id": "X4YodUXP"
    },
    "lmoeTqtV": {
        "authors": [
            {
                "name": "Junjie Li",
                "org": "Molecular Small Animal Imaging Centre/MoSAIC"
            },
            {
                "name": "Marlein Miranda Cona",
                "org": "Molecular Small Animal Imaging Centre/MoSAIC"
            },
            {
                "name": "Feng Chen",
                "org": "Molecular Small Animal Imaging Centre/MoSAIC"
            },
            {
                "name": "Yuanbo Feng",
                "org": "Molecular Small Animal Imaging Centre/MoSAIC"
            },
            {
                "name": "Lin Zhou",
                "org": "Nuclear Medicine and Molecular Imaging"
            },
            {
                "name": "Guozhi Zhang",
                "org": "Theranostic Laboratory"
            },
            {
                "name": "Johan Nuyts",
                "org": "Nuclear Medicine and Molecular Imaging"
            },
            {
                "name": "Peter de Witte",
                "org": "Faculty of Pharmaceutical Sciences"
            },
            {
                "name": "Jian Zhang",
                "org": "Laboratory of Translational Medicine"
            },
            {
                "name": "Jie Yu",
                "org": "Theranostic Laboratory"
            },
            {
                "name": "Raymond Oyen",
                "org": "Radiology Section"
            },
            {
                "name": "Alfons Verbruggen",
                "org": "Faculty of Pharmaceutical Sciences"
            },
            {
                "name": "Yicheng Ni",
                "org": "Laboratory of Translational Medicine"
            }
        ],
        "title": "Sequential systemic administrations of combretastatin A4 phosphate and radioiodinated hypericin exert synergistic targeted theranostic effects with prolonged survival on scid mice carrying bifocal tumor xenografts",
        "abstract": "Objectives: Based on the soil-to-seeds principle, we explored the small-molecular sequential dual- targeting theranostic strategy (SMSDTTS) for prolonged survival and imaging detectability in a xenograft tumor model. Materials and Methods: Thirty severe combined immunodeficiency (SCID) mice bearing bilateral radiation-induced fibrosarcoma-1 (RIF-1) subcutaneously were divided into group A of SMSDTTS with sequential intravenous injections of combretastatin A4 phosphate (CA4P) and ",
        "keywords": [
            "Necrosis targeting radiotherapy",
            "Radiation-induced fibrosarcoma-1 (RIF-1)",
            "Survival",
            "Synergistic antitumor effects",
            "Vascular disrupting agents (VDAs)"
        ],
        "venue": "Theranostics",
        "year": 2013,
        "id": "lmoeTqtV"
    },
    "d3jrA9Yg": {
        "authors": [
            {
                "name": "Bin Jiao",
                "org": "Department of Neurology"
            },
            {
                "name": "Ji-Feng Guo",
                "org": "Key Laboratory of Hunan Province in Neurodegenerative Disorders"
            },
            {
                "name": "Ya-Qin Wang",
                "org": "Department of Neurology"
            },
            {
                "name": "Xin-Xiang Yan",
                "org": "Key Laboratory of Hunan Province in Neurodegenerative Disorders"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Hunan Province in Neurodegenerative Disorders"
            },
            {
                "name": "Xiao-Yan Liu",
                "org": "Department of Neurology"
            },
            {
                "name": "Fu-Feng Zhang",
                "org": "Key Laboratory of Hunan Province in Neurodegenerative Disorders"
            },
            {
                "name": "Ya-Fang Zhou",
                "org": "Key Laboratory of Hunan Province in Neurodegenerative Disorders"
            },
            {
                "name": "Kun Xia",
                "org": "Key Laboratory of Hunan Province in Neurodegenerative Disorders"
            },
            {
                "name": "Bei-Sha Tang",
                "org": "Key Laboratory of Hunan Province in Neurodegenerative Disorders"
            },
            {
                "name": "Lu Shen",
                "org": "Key Laboratory of Hunan Province in Neurodegenerative Disorders"
            }
        ],
        "title": "C9orf72 mutation is rare in Alzheimer's disease, Parkinson's disease, and essential tremor in China",
        "abstract": "GGGGCC repeat expansions in the C9orf72 gene have been identified as a major contributing factor in patients with amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Given the overlapping of clinical phenotypes and pathological characteristics between these two diseases and Alzheimer's disease (AD), Parkinson's disease (PD), and essential tremor (ET), we speculated regarding whether C9orf72 repeat expansions also play a major role in these three diseases. Using the repeat-primed polymerase chain reaction method, we screened for C9orf72 in three groups of patients with PD (n = 911), AD (n = 279), and ET (n = 152) in the Chinese Han population. There were no pathogenic repeats (>30 repeats) detected in either the patients or controls (n = 314), which indicated that the pathogenic expansions of C9orf72 might be rare in these three diseases. However, the analysis of the association between the number of repeats (p = 0.001), short/intermediate genotype (short: <7 repeats; intermediate: \u22657 repeats) (odds ratio 1.37 [1.05, 1.79]), intermediate/intermediate genotype (Odds ratio 2.03 [1.17, 3.54]), and PD risks indicated that intermediate repeat alleles could act as contributors to PD. To the best of our knowledge, this study is the first to reveal the correlation between C9orf72 and Chinese PD, AD, or ET patients. Additionally, the results of this study suggest the novel idea that the intermediate repeat allele in C9orf72 is most likely a risk factor for PD. \u00a9 2013 Jiao, Guo, Wang, Yan, Zhou, Liu, Zhang, Zhou, Xia, Tang and Shen.",
        "keywords": [
            "Alzheimer's disease",
            "C9orf72",
            "Essential tremor",
            "Parkinson's disease",
            "Risk factor"
        ],
        "venue": "Frontiers in Cellular Neuroscience",
        "year": 2013,
        "id": "d3jrA9Yg"
    },
    "JaLseZl2": {
        "authors": [
            {
                "name": "Changsheng Gan",
                "org": "Engineering Research Center of Bio-process of Ministry of Education"
            },
            {
                "name": "Lin Zhou",
                "org": "Engineering Research Center of Bio-process of Ministry of Education"
            },
            {
                "name": "Zhenzhen Zhao",
                "org": "Engineering Research Center of Bio-process of Ministry of Education"
            },
            {
                "name": "Haoshu Wang",
                "org": "Engineering Research Center of Bio-process of Ministry of Education"
            }
        ],
        "title": "Benzothiazole Schiff-bases as potential imaging agents for \u03b2-amyloid plaques in Alzheimer's disease",
        "abstract": "A series of benzothiazole Schiff-bases as potential diagnostic imaging agents targeting \u03b2-amyloid (A\u03b2) plaques in Alzheimer's disease (AD) were synthesized and evaluated. When in vitro binding studies using AD homogenate with [",
        "keywords": [
            "Alzheimer's disease",
            "Amyloid plaques",
            "Benzothiazole",
            "Binding affinity",
            "Schiff-bases"
        ],
        "venue": "Medicinal Chemistry Research",
        "year": 2013,
        "id": "JaLseZl2"
    },
    "mvvPF3pv": {
        "authors": [
            {
                "name": "Jinli Wang",
                "org": "Key Laboratory of Tropical Diseases Control (Sun Yat-sen University)"
            },
            {
                "name": "Kun Yang",
                "org": "Key Laboratory of Tropical Diseases Control (Sun Yat-sen University)"
            },
            {
                "name": "Lin Zhou",
                "org": "Center for Tuberculosis Control of Guangdong Province"
            },
            {
                "name": "Minhao Wu",
                "org": "Key Laboratory of Tropical Diseases Control (Sun Yat-sen University)"
            },
            {
                "name": "Yongjian Wu",
                "org": "Key Laboratory of Tropical Diseases Control (Sun Yat-sen University)"
            },
            {
                "name": "Min Zhu",
                "org": "Key Laboratory of Tropical Diseases Control (Sun Yat-sen University)"
            },
            {
                "name": "XiaoMin Lai",
                "org": "Key Laboratory of Tropical Diseases Control (Sun Yat-sen University)"
            },
            {
                "name": "Tao Chen",
                "org": "Center for Tuberculosis Control of Guangdong Province"
            },
            {
                "name": "Lianqiang Feng",
                "org": "Key Laboratory of Tropical Diseases Control (Sun Yat-sen University)"
            },
            {
                "name": "Meiyu Li",
                "org": "Key Laboratory of Tropical Diseases Control (Sun Yat-sen University)"
            },
            {
                "name": "Chunyu Huang",
                "org": "Key Laboratory of Tropical Diseases Control (Sun Yat-sen University)"
            },
            {
                "name": "Qiu Zhong",
                "org": "Center for Tuberculosis Control of Guangdong Province"
            },
            {
                "name": "Xi Huang",
                "org": "Key Laboratory of Tropical Diseases Control (Sun Yat-sen University)"
            }
        ],
        "title": "MicroRNA-155 Promotes Autophagy to Eliminate Intracellular Mycobacteria by Targeting Rheb",
        "abstract": "Mycobacterium tuberculosis is a hard-to-eradicate intracellular pathogen that infects one-third of the global population. It can live within macrophages owning to its ability to arrest phagolysosome biogenesis. Autophagy has recently been identified as an effective way to control the intracellular mycobacteria by enhancing phagosome maturation. In the present study, we demonstrate a novel role of miR-155 in regulating the autophagy-mediated anti-mycobacterial response. Both in vivo and in vitro studies showed that miR-155 expression was significantly enhanced after mycobacterial infection. Forced expression of miR-155 accelerated the autophagic response in macrophages, thus promoting the maturation of mycobacterial phagosomes and decreasing the survival rate of intracellular mycobacteria, while transfection with miR-155 inhibitor increased mycobacterial survival. However, macrophage-mediated mycobacterial phagocytosis was not affected after miR-155 overexpression or inhibition. Furthermore, blocking autophagy with specific inhibitor 3-methyladenine or silencing of autophagy related gene 7 (Atg7) reduced the ability of miR-155 to promote autophagy and mycobacterial elimination. More importantly, our study demonstrated that miR-155 bound to the 3\u2032-untranslated region of Ras homologue enriched in brain (Rheb), a negative regulator of autophagy, accelerated the process of autophagy and sequential killing of intracellular mycobacteria by suppressing Rheb expression. Our results reveal a novel role of miR-155 in regulating autophagy-mediated mycobacterial elimination by targeting Rheb, and provide potential targets for clinical treatment. \u00a9 2013 Wang et al.",
        "keywords": [
            ""
        ],
        "venue": "PLoS Pathogens",
        "year": 2013,
        "id": "mvvPF3pv"
    },
    "nfwzsTV2": {
        "authors": [
            {
                "name": "Jie Feng",
                "org": "Department of Neurology"
            },
            {
                "name": "Yun-Hai Liu",
                "org": "Department of Neurology"
            },
            {
                "name": "Qi-Dong Yang",
                "org": "Department of Neurology"
            },
            {
                "name": "Zan-Hua Zhu",
                "org": "State Key Laboratory of Medical Genetics of China"
            },
            {
                "name": "Kun Xia",
                "org": "State Key Laboratory of Medical Genetics of China"
            },
            {
                "name": "Xing-Lin Tan",
                "org": "Department of Neurology"
            },
            {
                "name": "Jian Xia",
                "org": "Department of Neurology"
            },
            {
                "name": "Wen-Ping Gu",
                "org": "Department of Neurology"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Neurology"
            },
            {
                "name": "Bo Xiao",
                "org": "Department of Neurology"
            },
            {
                "name": "Bei-Sha Tang",
                "org": "Department of Neurology"
            },
            {
                "name": "Qing Huang",
                "org": "Department of Neurology"
            }
        ],
        "title": "TNFSF4 gene polymorphism rs3861950 but not rs3850641 is associated with the risk of cerebral infarction in a Chinese population",
        "abstract": "Tumor necrosis factor superfamily member 4 (TNFSF4) plays a key role in the process of atherosclerosis, a common risk factor for both myocardial and cerebral infarctions. Recent studies indicate that the single nucleotide polymorphism (SNP) rs3850641 in TNFSF4 is associated with higher risk of myocardial infarction, but little is known about the association between TNFSF4 variation and cerebral infarction (CI). A case-control study involving 385 CI patients and 385 age-matched, sex-matched non-CI controls was conducted in a Chinese population, only the most common subtype, atherosclerosis CI, was recruited. Two SNPs of TNFSF4, rs3850641 and rs3861950, were genotyped by the TaqMan SNP genotyping method, and verified partly by genomic DNA sequencing. The results revealed a significant allelic association between rs3861950 and CI (Odds ration = 1.733, 95 % confidence interval = 1.333-2.254, P = 0.000). Genotypic association analysis demonstrated that the CC genotype of rs3861950 confers susceptibility to CI (Odds ration = 2.896, 95 % confidence interval = 1.368-6.132), and it was associated with a significantly higher risk of ischemic stroke (Odds ration = 3.520, 95 % confidence interval = 1.546-8.015, P = 0.003) after adjusting for the other confirmed risk factors such as the history of hypertension, diabetes, CAD, smoking and alcohol drinking. While the odds ratio of the T allele to the C allele was 1.733 (95 % confidence interval: 1.333-2.254). However, there was no significant association between rs3850641 and CI (Odds ration = 1.288, 95 % confidence interval = 0.993-1.670, P = 0.056). TNFSF4 gene polymorphism rs3861950, but not rs3850641, is associated with the risk of atherosclerosis CI in a Chinese population. \u00a9 2012 Springer Science+Business Media New York.",
        "keywords": [
            "Atherosclerosis",
            "Cerebral infarction",
            "Genotype",
            "Polymorphism",
            "SNP",
            "TNFSF4"
        ],
        "venue": "Journal of Thrombosis and Thrombolysis",
        "year": 2013,
        "id": "nfwzsTV2"
    },
    "Rd7Svi4Y": {
        "authors": [
            {
                "name": "Bai-Ye Jin",
                "org": "Department of Urology"
            },
            {
                "name": "Guang-Hou Fu",
                "org": "Department of Urology"
            },
            {
                "name": "Xue Jiang",
                "org": "Department of Nephrology"
            },
            {
                "name": "Hao Pan",
                "org": "Department of Urology"
            },
            {
                "name": "Dong-Kai Zhou",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Xu-Yong Wei",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Lee Chung",
                "org": "Department of Urology"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            }
        ],
        "title": "CRABP2 and FABP5 identified by 2D DIGE profiling are upregulated in human bladder cancer",
        "abstract": "",
        "keywords": [
            "2D DIGE",
            "Biomarker",
            "Bladder cancer",
            "CRABP2",
            "FABP5"
        ],
        "venue": "Chinese Medical Journal",
        "year": 2013,
        "id": "Rd7Svi4Y"
    },
    "btZ4rocU": {
        "authors": [
            {
                "name": "Yuanbo Feng",
                "org": "Department of Imaging and Pathology"
            },
            {
                "name": "Marlein Miranda Cona",
                "org": "Department of Imaging and Pathology"
            },
            {
                "name": "Kathleen Vunckx",
                "org": "Department of Imaging and Pathology"
            },
            {
                "name": "Yue Li",
                "org": "Laboratory of Translational Medicine"
            },
            {
                "name": "Feng Chen",
                "org": "Department of Imaging and Pathology"
            },
            {
                "name": "Johan Nuyts",
                "org": "Department of Imaging and Pathology"
            },
            {
                "name": "Olivier Gheysens",
                "org": "Department of Imaging and Pathology"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Imaging and Pathology"
            },
            {
                "name": "Yi Xie",
                "org": "Departments of Electronics and Information System (ELIS)"
            },
            {
                "name": "Raymond Oyen",
                "org": "Department of Imaging and Pathology"
            },
            {
                "name": "Yicheng Ni",
                "org": "Department of Imaging and Pathology"
            }
        ],
        "title": "Detection and quantification of acute reperfused myocardial infarction in rabbits using DISA-SPECT/CT and 3.0 T cardiac MRI",
        "abstract": "Background Necrosis avid tracer ",
        "keywords": [
            "123I-hypericin",
            "Autoradiography",
            "MRI",
            "Myocardial infarction",
            "Rabbit model",
            "SPECT"
        ],
        "venue": "International Journal of Cardiology",
        "year": 2013,
        "id": "btZ4rocU"
    },
    "nlAP1Ddu": {
        "authors": [
            {
                "name": "Hongtai Zhang",
                "org": "State Key Laboratory of Biomacromolecules"
            },
            {
                "name": "Dongfang Li",
                "org": "Shenzhen Key Laboratory of Unknown Pathogen Identification"
            },
            {
                "name": "Lili Zhao",
                "org": "State Key Laboratory for Infectious Disease Prevention and Control"
            },
            {
                "name": "Joy Fleming",
                "org": "Key Laboratory of Non-coding RNA"
            },
            {
                "name": "Nan Lin",
                "org": "College of Life Sciences"
            },
            {
                "name": "Ting Wang",
                "org": "Key Laboratory of Non-coding RNA"
            },
            {
                "name": "Zhangyi Liu",
                "org": "BGI-Shenzhen"
            },
            {
                "name": "Chuanyou Li",
                "org": "Beijing Chest Hospital"
            },
            {
                "name": "Nicholas Galwey",
                "org": "Key Laboratory of Non-coding RNA"
            },
            {
                "name": "Jiaoyu Deng",
                "org": "State Key Laboratory of Virology"
            },
            {
                "name": "Ying Zhou",
                "org": "Key Laboratory of Non-coding RNA"
            },
            {
                "name": "Yuanfang Zhu",
                "org": "BGI-Shenzhen"
            },
            {
                "name": "Yunrong Gao",
                "org": "Key Laboratory of Non-coding RNA"
            },
            {
                "name": "Tong Wang",
                "org": "BGI-Shenzhen"
            },
            {
                "name": "Shihua Wang",
                "org": "College of Life Sciences"
            },
            {
                "name": "Yufen Huang",
                "org": "BGI-Shenzhen"
            },
            {
                "name": "Ming Wang",
                "org": "Key Laboratory of Non-coding RNA"
            },
            {
                "name": "Qiu Zhong",
                "org": "Center for Tuberculosis Control of Guangdong Province"
            },
            {
                "name": "Lin Zhou",
                "org": "Center for Tuberculosis Control of Guangdong Province"
            },
            {
                "name": "Tao Chen",
                "org": "Center for Tuberculosis Control of Guangdong Province"
            },
            {
                "name": "Jie Zhou",
                "org": "Fourth People's Hospital"
            },
            {
                "name": "Ruifu Yang",
                "org": "BGI-Shenzhen"
            },
            {
                "name": "Guofeng Zhu",
                "org": "Shanghai Municipal Center for Disease Control and Prevention"
            },
            {
                "name": "Haiying Hang",
                "org": "Key Laboratory of Non-coding RNA"
            },
            {
                "name": "Jia Zhang",
                "org": "Key Laboratory of Non-coding RNA"
            },
            {
                "name": "Fabin Li",
                "org": "Heilongjiang Center for Tuberculosis Control and Prevention"
            },
            {
                "name": "Kanglin Wan",
                "org": "State Key Laboratory for Infectious Disease Prevention and Control"
            },
            {
                "name": "Jun Wang",
                "org": "BGI-Shenzhen"
            },
            {
                "name": "Xian-En Zhang",
                "org": "State Key Laboratory of Virology"
            },
            {
                "name": "Lijun Bi",
                "org": "Key Laboratory of Non-coding RNA"
            }
        ],
        "title": "Genome sequencing of 161 Mycobacterium tuberculosis isolates from China identifies genes and intergenic regions associated with drug resistance",
        "abstract": "The worldwide emergence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis threatens to make this disease incurable. Drug resistance mechanisms are only partially understood, and whether the current understanding of the genetic basis of drug resistance in M. Tuberculosis is sufficiently comprehensive remains unclear. Here we sequenced and analyzed 161 isolates with a range of drug resistance profiles, discovering 72 new genes, 28 intergenic regions (IGRs), 11 nonsynonymous SNPs and 10 IGR SNPs with strong, consistent associations with drug resistance. On the basis of our examination of the dN/dS ratios of nonsynonymous to synonymous SNPs among the isolates, we suggest that the drug resistance-Associated genes identified here likely contain essentially all the nonsynonymous SNPs that have arisen as a result of drug pressure in these isolates and should thus represent a near-complete set of drug resistance-Associated genes for these isolates and antibiotics. Our work indicates that the genetic basis of drug resistance is more complex than previously anticipated and provides a strong foundation for elucidating unknown drug resistance mechanisms. \u00a9 2013 Nature America, Inc. All rights reserved.",
        "keywords": [
            ""
        ],
        "venue": "Nature Genetics",
        "year": 2013,
        "id": "nlAP1Ddu"
    },
    "AKv9TrY0": {
        "authors": [
            {
                "name": "Te Zhao",
                "org": "College of Plant Protection"
            },
            {
                "name": "Fei Gao",
                "org": "College of Plant Protection"
            },
            {
                "name": "Lin Zhou",
                "org": "College of Plant Protection"
            },
            {
                "name": "Tian-you Song",
                "org": "College of Plant Protection"
            }
        ],
        "title": "Essential oil from Inula britannica extraction with SF-CO2 and its antifungal activity",
        "abstract": "The aim of this study was to determine the extraction technique of supercritical fluid carbon dioxide (SF-CO",
        "keywords": [
            "Antifungal activity",
            "Botanical fungicide",
            "Essential oil",
            "Inula britannica",
            "Optimization",
            "Supercritical fluid carbon dioxide extraction"
        ],
        "venue": "Journal of Integrative Agriculture",
        "year": 2013,
        "id": "AKv9TrY0"
    },
    "Jm7KIRbU": {
        "authors": [
            {
                "name": "Jie Ji",
                "org": "Key Laboratory of Green Chemistry and Technology"
            },
            {
                "name": "Lili Lin",
                "org": "Key Laboratory of Green Chemistry and Technology"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Green Chemistry and Technology"
            },
            {
                "name": "Yuheng Zhang",
                "org": "Key Laboratory of Green Chemistry and Technology"
            },
            {
                "name": "Yangbin Liu",
                "org": "Key Laboratory of Green Chemistry and Technology"
            },
            {
                "name": "Xiaohua Liu",
                "org": "Key Laboratory of Green Chemistry and Technology"
            },
            {
                "name": "Xiaoming Feng",
                "org": "Key Laboratory of Green Chemistry and Technology"
            }
        ],
        "title": "N,N'-dioxide-scandium (III)-catalyzed asymmetric Michael addition of \u03b2,\u03b3-unsaturated butenolides to \u03b1,\u03b2-unsaturated \u03b3-keto esters",
        "abstract": "A highly efficient N,N'-dioxide-scandium-(III) complex catalytic system has been developed for the asymmetric vinylogous Michael reaction of a-angelica lactone and its derivatives to \u03b1,\u03b2-Unsaturated \u03b3-Keto esters, affording the corresponding \u03b3,\u03b3-disubstituted butenolide products in moderate to good yields (up to 93%) with high dr (up to >19:1) and ee values (up to 97%) under mild reaction conditions. \u00a9 2013 Wiley-VCH Verlag GmbH&Co. KGaA, Weinheim.",
        "keywords": [
            "Asymmetric catalysis",
            "G-butenolides",
            "Michael addition",
            "NN'-dioxides",
            "Scandium"
        ],
        "venue": "Advanced Synthesis and Catalysis",
        "year": 2013,
        "id": "Jm7KIRbU"
    },
    "6fq3XLEL": {
        "authors": [
            {
                "name": "Zhen Wang",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Yukai Liu",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Yu Han",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Weiwei Guan",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Xun Kou",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Jinjuan Fu",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Di Yang",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Hongmei Ren",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Duofen He",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Lin Zhou",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Chunyu Zeng",
                "org": "Chongqing Institute of Cardiology"
            }
        ],
        "title": "Protective effects of aliskiren on ischemia-reperfusion-induced renal injury in rats",
        "abstract": "The protective effect of aliskiren on ischemia-reperfusion (I/R) injury in the heart and brain has been reported. Whether or not this protective effect extends into the alleviation of renal I/R injury is not known. Therefore, we investigated the protective effect of aliskiren in the kidney in this study. Sprague-Dawley rats were randomly divided into four groups: sham control group; sham control with aliskiren pretreatment; I/R group and I/R with aliskiren pretreatment. Aliskiren (3 mg/kg) or vehicle was administrated intravenously via vena cava. Blood samples and the left kidneys were then collected to check for renal function, angiotensin II (Ang II), apoptosis and oxidative stress levels. Compared with the sham rats, serum creatinine (SCR) and blood urea nitrogen (BUN) were significantly increased in the I/R rats, accompanied by histopathological damage to the kidney, which included tubular cell swelling, desquamation, and cast formation. There were also more apoptotic cells and leukocyte infiltration in the I/R rats than in the sham rats. Pretreatment with aliskiren ameliorated I/R induced renal injury, i.e. reduced SCR and BUN levels, ameliorated renal histopathological changes, and decreased the apoptosis of cells and leukocyte infiltration in kidney. I/R injury also decreased superoxide dismutase (SOD) and glutathione (GSH-reduced form) levels, which were blocked with the aliskiren pretreatment. Aliskiren pretreatment exerts a protective effect on ischemia/reperfusion injury in the kidney, via amelioration of oxidative stress, and reduction in leukocyte infiltration and cellular apoptosis. \u00a9 2013 Published by Elsevier B.V. All rights reserved.",
        "keywords": [
            "Aliskiren",
            "Angiotensin II",
            "Apoptosis",
            "Oxidative stress",
            "Renal ischemia-reperfusion"
        ],
        "venue": "European Journal of Pharmacology",
        "year": 2013,
        "id": "6fq3XLEL"
    },
    "2XM2Dmrg": {
        "authors": [
            {
                "name": "Fenqiang Xiao",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Wu Zhang",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Haiyang Xie",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Chunyang Xing",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Songming Ding",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Kangjie Chen",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Shusen Zheng",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            }
        ],
        "title": "MicroRNA-200a is an independent prognostic factor of hepatocellular carcinoma and induces cell cycle arrest by targeting CDK6",
        "abstract": "Deregulation of microRNA-200a (miR-200a) has been observed in different types of diseases, including cancers. However, the exact roles of miR-200a in hepatocellular carcinoma (HCC) are still largely unknown. We aimed to elucidate the prognostic implications of miR-200a and its biological function in HCC. Quantitative polymerase chain reaction was used to evaluate miR-200a expression. Western blotting was performed to evaluate the protein level. Gain-of-function studies were performed to evaluate the roles of miR-200a in HCC. Our results revealed that miR-200a was frequently downregulated in HCC. In addition, multivariate analysis confirmed that miR-200a was significantly associated with the overall survival of HCC patients. In vitro assays demonstrated that miR-200a suppressed the proliferation of HCC cells by induction of G1 phase arrest. Furthermore, CDK6 was identified as a novel functional target of miR-200a. Our data indicate that miR-200a functions as a potential tumor suppressor in HCC.",
        "keywords": [
            "CDK6",
            "Cell cycle arrest",
            "Hepatocellular carcinoma",
            "MicroRNA-200a",
            "Overall survival"
        ],
        "venue": "Oncology Reports",
        "year": 2013,
        "id": "2XM2Dmrg"
    },
    "ANmVK7BA": {
        "authors": [
            {
                "name": "Weilin Wang",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Pengfei Huang",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Lufei Zhang",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Jianfeng Wei",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Qingsong Xie",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Qiang Sun",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Xiaohu Zhou",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Haiyang Xie",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Shusen Zheng",
                "org": "Key Laboratory of Organ Transplantation"
            }
        ],
        "title": "Antitumor efficacy of C-X-C motif chemokine ligand 14 in hepatocellular carcinoma in vitro and in vivo",
        "abstract": "C-X-C motif chemokine ligand 14 (CXCL14) is a novel gene that is expressed in many normal cells but is absent from or expressed at very low levels in cancerous tissues such as head and neck squamous cell carcinoma (HNSCC), prostate cancer, and pancreatic cancer. However, the relationship between CXCL14 and hepatocellular carcinoma (HCC) remains unclear. Therefore, the exact function of CXCL14, which may modulate antitumor immune responses in certain cancers, was evaluated. CXCL14 was downregulated in HCC tissues compared to adjacent normal tissues. Moreover, overexpression of CXCL14 had an inhibitory effect on cell proliferation, induced apoptosis and inhibited the invasion of HCC cells in vitro. Upregulation of CXCL14 by lentivirus also significantly suppressed the growth of subcutaneous tumors in nude mice in vivo. We further demonstrated that the loss of CXCL14 expression was regulated by promoter hypermethylation. CXCL14 induced tumor cell apoptosis through both the mitochondrial and nuclear apoptosis pathways. CXCL14 suppressed tumor cell proliferation through regulation of the cell cycle by downregulation of cyclins and cyclin-dependent kinases. In conclusion, CXCL14 plays a pivotal role as a potential tumor suppressor in HCC. The re-expression or upregulation of this gene may provide a novel strategy in HCC therapy in the future. \u00a9 2013 Japanese Cancer Association.",
        "keywords": [
            ""
        ],
        "venue": "Cancer Science",
        "year": 2013,
        "id": "ANmVK7BA"
    },
    "byJxCBaQ": {
        "authors": [
            {
                "name": "Yue Chen",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Laureano D. Asico",
                "org": "Division of Nephrology"
            },
            {
                "name": "Shuo Zheng",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Van Anthony M. Villar",
                "org": "Division of Nephrology"
            },
            {
                "name": "Duofen He",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Lin Zhou",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Chunyu Zeng",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Pedro A. Jose",
                "org": "Division of Nephrology"
            }
        ],
        "title": "Gastrin and D1 dopamine receptor interact to induce natriuresis and diuresis",
        "abstract": "Oral NaCl produces a greater natriuresis and diuresis than the intravenous infusion of the same amount of NaCl. Gastrin is the major gastrointestinal hormone taken up by renal proximal tubule (RPT) cells. We hypothesized that renal gastrin and dopamine receptors interact to synergistically increase sodium excretion, an impaired interaction of which may be involved in the pathogenesis of hypertension. In Wistar-Kyoto rats, infusion of gastrin induced natriuresis and diuresis, which was abrogated in the presence of a gastrin (cholecystokinin B receptor [CCKBR]; CI-988) or a D1-like receptor antagonist (SCH23390). Similarly, the natriuretic and diuretic effects of fenoldopam, a D1-like receptor agonist, were blocked by SCH23390, as well as by CI-988. However, the natriuretic effects of gastrin and fenoldopam were not observed in spontaneously hypertensive rats. The gastrin/D1-like receptor interaction was also confirmed in RPT cells. In RPT cells from Wistar-Kyoto but not spontaneously hypertensive rats, stimulation of either D1-like receptor or gastrin receptor inhibited Na-K-ATPase activity, an effect that was blocked in the presence of SCH23390 or CI-988. In RPT cells from Wistar-Kyoto and spontaneously hypertensive rats, CCKBR and D1 receptor coimmunoprecipitated, which was increased after stimulation of either D1 receptor or CCKBR in RPT cells from Wistar-Kyoto rats; stimulation of one receptor increased the RPT cell membrane expression of the other receptor, effects that were not observed in spontaneously hypertensive rats. These data suggest that there is a synergism between CCKBR and D1-like receptors to increase sodium excretion. An aberrant interaction between the renal CCK BR and D1-like receptors (eg, D1 receptor) may play a role in the pathogenesis of hypertension. \u00a9 2013 American Heart Association, Inc.",
        "keywords": [
            "hypertension",
            "kidney",
            "kidney tubules proximal",
            "receptor cholecystokinin B",
            "receptors dopamine D1"
        ],
        "venue": "Hypertension",
        "year": 2013,
        "id": "byJxCBaQ"
    },
    "oGWERA6d": {
        "authors": [
            {
                "name": "Zhen Wang",
                "org": "Department of Neurobiology"
            },
            {
                "name": "Ya-Nan Wang",
                "org": "Department of Neurobiology"
            },
            {
                "name": "Cheng-Long Sun",
                "org": "Department of Neurobiology"
            },
            {
                "name": "Dong Yang",
                "org": "Department of Neurobiology"
            },
            {
                "name": "Li-Da Su",
                "org": "Department of Neurobiology"
            },
            {
                "name": "Ya-Jun Xie",
                "org": "Department of Neurobiology"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Neurobiology"
            },
            {
                "name": "Yin Wang",
                "org": "Department of Neurobiology"
            },
            {
                "name": "Ying Shen",
                "org": "Department of Neurobiology"
            }
        ],
        "title": "C-terminal domain of ICA69 interacts with PICK1 and acts on trafficking of PICK1-PKC\u03b1 complex and cerebellar plasticity",
        "abstract": "Background: PICK1 (protein interacting with C-kinase 1) is a PKC (protein kinase C)-binding protein, which is essential for synaptic plasticity. The trafficking of PKC\u03b1-PICK1 complex to plasma membrane is critical for the internalization of GluR2 and induction of long-term depression. ICA69 (islet cell autoantigen 69 kDa) is identified as a major binding partner of PICK1. While heteromeric BAR domain complex is suggested to underlie the interaction between PICK1 and ICA69, the role of C-terminal domain of ICA69 (ICAC) in PICK1-ICA69 complex is unknown. Methodology/Principal Findings: We found that ICAC interacted with PICK1 and regulated the trafficking of PICK1-PKC\u03b1 complex. ICAC and \u0394ICAC (containing BAR domain) might function distinctly in the association of ICA69 with PICK1. While \u0394ICAC domain inclined to form clusters, the distribution of ICAC was diffuse. The trafficking of PICK1 to plasma membrane mediated by activated PKC\u03b1 was inhibited by ICA69. This action might ascribe to ICAC, because overexpression of ICAC, but not \u0394ICAC, interrupted PKC\u03b1-mediated PICK1 trafficking. Notably, infusion of maltose binding protein (MBP) fusion protein, MBP-ICA69 or MBP-ICAC, in cerebellar Purkinje cells significantly inhibited the induction of long-term depression at parallel fiber- and climbing fiber-Purkinje cell synapses. Conclusions: Our experiments showed that ICAC is an important domain for the ICA69-PICK1 interaction and plays essential roles in PICK1-mediated neuronal plasticity. \u00a9 2013 Wang et al.",
        "keywords": [
            ""
        ],
        "venue": "PLoS ONE",
        "year": 2013,
        "id": "oGWERA6d"
    },
    "N1G6apxU": {
        "authors": [
            {
                "name": "Yat Fung Shea",
                "org": "Department of Medicine"
            },
            {
                "name": "Leung-Wing Chu",
                "org": "Alzheimer's Disease Research Network"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Medicine"
            },
            {
                "name": "Wing-Man Li",
                "org": "Department of Medicine"
            },
            {
                "name": "Oi Yee Lin",
                "org": "Department of Medicine"
            },
            {
                "name": "May N. Y. Chan",
                "org": "Department of Medicine"
            },
            {
                "name": "Aimin Xu",
                "org": "Department of Medicine"
            },
            {
                "name": "Rachel Wong",
                "org": "Department of Medicine"
            },
            {
                "name": "Tip Yin Ho",
                "org": "Department of Medicine"
            },
            {
                "name": "Kin Wah Liu",
                "org": "Department of Medicine"
            },
            {
                "name": "Joyce Ha",
                "org": "Department of Medicine"
            },
            {
                "name": "T.W. Daniel",
                "org": "Department of Medicine"
            },
            {
                "name": "You-Qiang Song",
                "org": "Department of Biochemistry"
            },
            {
                "name": "Karen S. Lam",
                "org": "Alzheimer's Disease Research Network"
            }
        ],
        "title": "Cerebrospinal fluid biomarkers of Alzheimer's disease in Chinese patients: A pilot study",
        "abstract": "In view of the paucity of data on cerebrospinal fluid (CSF) biomarkers in Chinese patients, we evaluated the validity of tau, phosphorylated tau 181 (p-tau-181), amyloid \u03b2 42 (A\u03b242), and A\u03b240 proteins in Chinese patients with Alzheimer's disease (AD). We recruited 24 patients with AD, 12 nondemented controls, and 12 patients with non-AD dementia. We found the CSF levels of A\u03b242, tau, p-tau, A\u03b242-tau, and A\u03b242-p-tau ratios, except the A\u03b240 protein level, were significantly different among the 3 groups of patients. Patients with AD had higher levels of CSF tau and p-tau but lower levels of A\u03b242 proteins, A\u03b242-tau, and A\u03b242-p-tau ratios than the nondemented controls. In the diagnosis of AD versus nondementia, the sensitivity and specificity of the ratios of A\u03b242-tau and A\u03b242-p-tau were 96% and 83% versus 92% and 83%, respectively. Only the A\u03b242-p-tau ratio showed satisfactory sensitivity and specificity in the diagnosis of AD versus other dementia. \u00a9 The Author(s) 2013.",
        "keywords": [
            "Alzheimer's disease",
            "biomarkers",
            "Chinese",
            "CSF"
        ],
        "venue": "American Journal of Alzheimer's Disease and other Dementias",
        "year": 2013,
        "id": "N1G6apxU"
    },
    "CWbrMrUA": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Cancer Biology and Xijing Hospital of Digestive Diseases"
            },
            {
                "name": "Xiaodi Zhao",
                "org": "State Key Laboratory of Cancer Biology and Xijing Hospital of Digestive Diseases"
            },
            {
                "name": "Yanan Han",
                "org": "State Key Laboratory of Cancer Biology and Xijing Hospital of Digestive Diseases"
            },
            {
                "name": "Yuanyuan Lu",
                "org": "State Key Laboratory of Cancer Biology and Xijing Hospital of Digestive Diseases"
            },
            {
                "name": "Yulong Shang",
                "org": "State Key Laboratory of Cancer Biology and Xijing Hospital of Digestive Diseases"
            },
            {
                "name": "Changhao Liu",
                "org": "State Key Laboratory of Cancer Biology and Xijing Hospital of Digestive Diseases"
            },
            {
                "name": "Ting Li",
                "org": "State Key Laboratory of Cancer Biology and Xijing Hospital of Digestive Diseases"
            },
            {
                "name": "Zhian Jin",
                "org": "State Key Laboratory of Cancer Biology and Xijing Hospital of Digestive Diseases"
            },
            {
                "name": "Daiming Fan",
                "org": "State Key Laboratory of Cancer Biology and Xijing Hospital of Digestive Diseases"
            },
            {
                "name": "Kaichun Wu",
                "org": "State Key Laboratory of Cancer Biology and Xijing Hospital of Digestive Diseases"
            }
        ],
        "title": "Regulation of UHRF1 by miR-146a/b modulates gastric cancer invasion and metastasis",
        "abstract": "Epigenetic changes play significant roles in the development of cancer. UHRF1, as an epigenetic regulator, has been shown to be overexpressed and to coordinate tumor suppressor gene silencing in several cancers. However, the role and underlying mechanism of UHRF1 in gastric cancer (GC) progression remain largely unknown. In this study, we investigated the expression and function of UHRF1 in GC metastasis and explored its upstream regulatory mechanisms at the microRNA level. UHRF1 was overexpressed in GC tissues, especially in metastatic ones, and a high level of UHRF1 expression predicted poor survival. The downregulation of UHRF1 suppressed GC invasion and metastasis in vitro and in vivo. We identified and verified miR-146a and miR-146b as direct upstream regulators of UHRF1. Furthermore, the restoration of miR-146a/b dramatically reduced the expression of UHRF1 through the direct targeting of its 3=-UTR, and this effect in turn reactivated the slit homologue 3 (Slit3), cadherin 4 (CDH4), and runt-related transcription factor 3 (RUNX3) genes via promoter demethylation. Finally, analyses of miR-146a/b and UHRF1 levels in human GC tissues revealed that miR-146a/b correlated inversely with UHRF1 expression. These findings describe a new mechanism for the regulation of UHRF1 and aberrant DNA hypermethylation in GC. The newly identified miR-146a/b/UHRF1 axis provides insight into the GC metastasis process, and targeting this novel axis represents a therapeutic approach to blocking GC metastasis.-Zhou, L., Zhao, X., Han, Y., Yuanyuan, L., Shang, Y., Liu, C., Li, T., Jin, Z., Fan, D., Wu, K. Regulation of UHRF1 by miR-146a/b modulates gastric cancer invasion and metastasis. \u00a9 FASEB.",
        "keywords": [
            "DNA methylation",
            "Metastasis"
        ],
        "venue": "FASEB Journal",
        "year": 2013,
        "id": "CWbrMrUA"
    },
    "2pWUpwB5": {
        "authors": [
            {
                "name": "Yan Zhao",
                "org": "Department of Digestive Interventional Radiology"
            },
            {
                "name": "Guohong Cai",
                "org": "Department of Digestive Interventional Radiology"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Digestive Interventional Radiology"
            },
            {
                "name": "Lei Liu",
                "org": "Department of Digestive Interventional Radiology"
            },
            {
                "name": "Xingshun Qi",
                "org": "Department of Digestive Interventional Radiology"
            },
            {
                "name": "Ming Bai",
                "org": "Department of Digestive Interventional Radiology"
            },
            {
                "name": "Yongping Li",
                "org": "Department of Vascular and Endocrine Surgery"
            },
            {
                "name": "Daiming Fan",
                "org": "State Key Laboratory of Cancer Biology and Xijing Hospital of Digestive Diseases"
            },
            {
                "name": "Guohong Han",
                "org": "Department of Digestive Interventional Radiology"
            }
        ],
        "title": "Transarterial chemoembolization in hepatocellular carcinoma with vascular invasion or extrahepatic metastasis: A systematic review",
        "abstract": "Aims: Advanced hepatocellular carcinoma (HCC) with vascular invasion or extrahepatic metastasis has been considered a contraindication for transarterial chemoembolization (TACE) treatment according to Barcelona Clinic Liver Cancer (BCLC) staging classification. However, real clinical practice varies among different countries. In recent years another opinion has been developing that considers that TACE can be safely performed in advanced HCC patients. Methods: All studies on the efficacy of TACE for patients with advanced HCC were identified via the PubMed database. The primary items were TACE and HCC. Results: We identified 15 studies in the treatment of TACE in advanced HCC patients. Most adverse events reported were treated successfully and in these studies there were no procedure-related deaths within 4 weeks of the TACE treatment. Four controlled studies reported that TACE increased survival rate and prolonged overall survival compared with conservative management. The most frequent prognostic factors were liver function and the degree of portal vein tumor thrombosis. Conclusion: TACE can be safely performed in advanced HCC patients with vascular invasion or extrahepatic spread and may improve their overall survival. Patients with portal vein branch invasion and well-preserved liver function seemed to derive optimal benefit from treatment with TACE. Further studies are needed to provide strong evidence of the efficacy of TACE for advanced HCC patients to update the BCLC staging system. \u00a9 2013 Wiley Publishing Asia Pty Ltd.",
        "keywords": [
            "Advanced hepatocellular carcinoma",
            "Transarterial chemoembolization",
            "Treatment"
        ],
        "venue": "Asia-Pacific Journal of Clinical Oncology",
        "year": 2013,
        "id": "2pWUpwB5"
    },
    "S5G2TCNW": {
        "authors": [
            {
                "name": "Yulong Zhang",
                "org": ""
            },
            {
                "name": "Xiaohua Liu",
                "org": ""
            },
            {
                "name": "Xiaohu Zhao",
                "org": ""
            },
            {
                "name": "Jianlin Zhang",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Lili Lin",
                "org": ""
            },
            {
                "name": "Xiaoming Feng",
                "org": ""
            }
        ],
        "title": "Enantioselective Friedel-Crafts alkylation for synthesis of 2-substituted indole derivatives",
        "abstract": "An efficient catalytic asymmetric intermolecular C2 Friedel-Crafts alkylation reaction between N-methyl skatole and \u03b2,\u03b3-unsaturated \u03b1-ketoesters has been realized by a chiral N,N\u2032-dioxide-Ni(ii) complex. The corresponding indole derivatives were obtained in good yield (up to 96%) with excellent enantioselectivities (up to 99% ee) under mild reaction conditions. \u00a9 2013 The Royal Society of Chemistry.",
        "keywords": [
            ""
        ],
        "venue": "Chemical Communications",
        "year": 2013,
        "id": "S5G2TCNW"
    },
    "s3KQGxT1": {
        "authors": [
            {
                "name": "Jian Wu",
                "org": "Department of Hepatobiliary Surgery"
            },
            {
                "name": "Chengli Du",
                "org": "Department of Hepatobiliary Surgery"
            },
            {
                "name": "Zhen Lv",
                "org": "Department of Hepatobiliary Surgery"
            },
            {
                "name": "Chaofeng Ding",
                "org": "Department of Hepatobiliary Surgery"
            },
            {
                "name": "Jun Cheng",
                "org": "Department of Hepatobiliary Surgery"
            },
            {
                "name": "Haiyang Xie",
                "org": "Department of Hepatobiliary Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Hepatobiliary Surgery"
            },
            {
                "name": "Shusen Zheng",
                "org": "Department of Hepatobiliary Surgery"
            }
        ],
        "title": "The up-regulation of histone deacetylase 8 promotes proliferation and inhibits apoptosis in hepatocellular carcinoma",
        "keywords": [
            "Acetylation of p53",
            "Apoptosis",
            "HDAC8",
            "Hepatocellular carcinoma (HCC)",
            "Intrinsic apoptotic pathways",
            "p53",
            "Proliferation"
        ],
        "venue": "Digestive Diseases and Sciences",
        "year": 2013,
        "id": "s3KQGxT1"
    },
    "FgvexWec": {
        "authors": [
            {
                "name": "Jianguo Wang",
                "org": ""
            },
            {
                "name": "Xiao Xu",
                "org": ""
            },
            {
                "name": "Zhikun Liu",
                "org": ""
            },
            {
                "name": "Xuyong Wei",
                "org": ""
            },
            {
                "name": "Runzhou Zhuang",
                "org": ""
            },
            {
                "name": "Di Lu",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Haiyang Xie",
                "org": ""
            },
            {
                "name": "Shusen Zheng",
                "org": ""
            }
        ],
        "title": "LEPREL1 expression in human hepatocellular carcinoma and its suppressor role on cell proliferation",
        "abstract": "Background. Hepatocellular carcinoma (HCC) is one of the most aggressive malignancies worldwide. It is characterized by its high invasive and metastatic potential. Leprecan-like 1 (LEPREL1) has been demonstrated to be downregulated in the HCC tissues in previous proteomics studies. The present study is aimed at a new understanding of LEPREL1 function in HCC. Methods. Quantitative RT-PCR, immunohistochemical analysis, and western blot analysis were used to evaluate the expression of LEPREL1 between the paired HCC tumor and nontumorous tissues. The biology function of LEPREL1 was investigated by Cell Counting Kit-8 (CCK8) assay and colony formation assay in HepG2 and Bel-7402 cells. Results. The levels of LEPREL1 mRNA and protein were significantly lower in the HCC tissues as compared to those of the nontumorous tissues. Reduced LEPREL1 expression was not associated with conventional clinical parameters of HCC. Overexpression of LEPREL1 in HepG2 and Bel-7402 cells inhibited cell proliferation (P < 0. 01) and colony formation (P < 0. 05). LEPREL1 suppressed tumor cell proliferation through regulation of the cell cycle by downregulation of cyclins. Conclusions. Clinical parameters analysis suggested that LEPREL1 was an independent factor in the development of HCC. The biology function experiments showed that LEPREL1 might serve as a potential tumor suppressor gene by inhibiting the HCC cell proliferation. \u00a9 2013 Jianguo Wang et al.",
        "keywords": [
            ""
        ],
        "venue": "Gastroenterology Research and Practice",
        "year": 2013,
        "id": "FgvexWec"
    },
    "51dvtibV": {
        "authors": [
            {
                "name": "Mingxin Xu",
                "org": "Institute of Digestive Disease, Tongji Hospital, Tongji University"
            },
            {
                "name": "Xiaolong Qi",
                "org": "Institute of Digestive Disease, Tongji Hospital, Tongji University"
            },
            {
                "name": "Haoming Song",
                "org": "Division of Cardiology, Tongji Hospital, Tongji University"
            },
            {
                "name": "Yujiao Liu",
                "org": "School of Pharmacy Bouv\u00e9, College of Health Sciences, Northeastern University"
            },
            {
                "name": "Lin Zhou",
                "org": "Division of Cardiology, Tongji Hospital, Tongji University"
            }
        ],
        "title": "Challenges in multislice computed tomography based fractional flow reserve to evaluate interventional treatment",
        "abstract": "",
        "keywords": [
            ""
        ],
        "venue": "Catheterization and Cardiovascular Interventions",
        "year": 2014,
        "id": "51dvtibV"
    },
    "0UQSDlW4": {
        "authors": [
            {
                "name": "Hong-Yu Xu",
                "org": "Department of Thoracic Oncology and State Key Laboratory of Biotherapy"
            },
            {
                "name": "Ze-Dong Du",
                "org": "Oncology Department"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Thoracic Oncology and State Key Laboratory of Biotherapy"
            },
            {
                "name": "Min Yu",
                "org": "Department of Thoracic Oncology and State Key Laboratory of Biotherapy"
            },
            {
                "name": "Zhen-Yu Ding",
                "org": "Department of Thoracic Oncology and State Key Laboratory of Biotherapy"
            },
            {
                "name": "You Lu",
                "org": "Department of Thoracic Oncology and State Key Laboratory of Biotherapy"
            }
        ],
        "title": "Safety and efficacy of radiation and chemoradiation in patients over 70 years old with inoperable esophageal squamous cell carcinoma",
        "abstract": "The aim of the present study was to perform a retrospective analysis to investigate the outcome and toxicity of radiation (RT) and chemoradiation (CRT) in elderly, inoperable patients >70 years old. Between 2003 and 2012, 1,024 patients with squamous cell carcinoma (SCC) of the esophagus were treated at the Department of Thoracic Cancer, West China Hospital (Chengdu, China). Of these patients, 37 were >70 years old and had not undergone surgery, and were selected for analysis. Of these 37 patients, CRT had been administered to 20 (54%). Actuarial survival rates were determined by the Kaplan-Meier method. The one-year survival rate in the CRT group (n=20) was 85%, while 35% of patients in the RT group (n=17) survived for more than one year. The overall and progression-free survival in the CRT group versus the RT group were 17 months [95% confidence interval (CI), 11.861-22.139] versus eight months (95% CI, 6.674-9.326) (P=0.013) and 14 months (95% CI, 9.617-18.383) versus five months (95% CI, 2.311-7.689) (P=0.01), respectively. Patients irradiated with a dose of >50 Gy exhibited an improved survival rate compared with patients who received a dose of \u226450 Gy (18 vs. 14 months; P=0.049). Furthermore, patients with an Eastern Cooperative Oncology Group (ECOG) score of \u22641 had an improved prognosis compared with those with an ECOG score of 2 (14 vs. seven months; P=0.006). The two regimens were well-tolerated and there were no therapy-associated mortalities. The current retrospective study indicated that patients of >70 years old with inoperable esophageal SCC and a good ECOG score exhibit comparably better safety levels with CRT and improved survival rates compared with RT alone.",
        "keywords": [
            "Chemoradiation",
            "Elderly",
            "Esophageal squamous cancer",
            "Radiation",
            "Toxicity"
        ],
        "venue": "Oncology Letters",
        "year": 2014,
        "id": "0UQSDlW4"
    },
    "ytaVZoJb": {
        "authors": [
            {
                "name": "Xiaolong Qi",
                "org": "Institute of Digestive Disease, Tongji Hospital, Tongji University School of Medicine"
            },
            {
                "name": "Fangyu Zhou",
                "org": "Institute of Digestive Disease, Tongji Hospital, Tongji University School of Medicine"
            },
            {
                "name": "Jun Wan",
                "org": "Division of Interventional Radiology, Shanghai Jing'an District Central Hospital"
            },
            {
                "name": "Lin Zhou",
                "org": "Division of Cardiology, Tongji Hospital, Tongji University School of Medicine"
            },
            {
                "name": "Wei Xu",
                "org": "Institute of Digestive Disease, Tongji Hospital, Tongji University School of Medicine"
            },
            {
                "name": "Juan Cheng",
                "org": "Institute of Digestive Disease, Tongji Hospital, Tongji University School of Medicine"
            },
            {
                "name": "Yu Mao",
                "org": "Division of Cardiology, Tongji Hospital, Tongji University School of Medicine"
            },
            {
                "name": "Wanrong Ma",
                "org": "Division of Cardiology, Tongji Hospital, Tongji University School of Medicine"
            },
            {
                "name": "Wenbin Ji",
                "org": "Institute of Digestive Disease, Tongji Hospital, Tongji University School of Medicine"
            },
            {
                "name": "Changqing Yang",
                "org": "Institute of Digestive Disease, Tongji Hospital, Tongji University School of Medicine"
            }
        ],
        "title": "Noninvasive assessment of cerebral artery stenoses from anatomic computed tomography angiography",
        "abstract": "Trans-stenotic pressure gradient (TSPG) and fractional flow reserve (FFR) are well-validated hemodynamic indices to assess the ischemic severity of arterial stenoses. However, they have significant restrictions in practice due to invasiveness and high cost. Recently, a noninvasive assessment of FFR from computed tomography (CT) angiography has been well validated in evaluating functional coronary stenoses. We present a case of a 65-year-old woman with cerebral artery stenoses demonstrated by clinical symptoms, transcranial Doppler ultrasound and CT angiography, aiming to transplant the noninvasive functional diagnosis, for the first time, to cerebral artery stenoses and test a computational workflow of noninvasive TSPG and FFR.",
        "keywords": [
            "Cerebral artery stenoses",
            "Fractional flow reserve",
            "Noninvasive",
            "Trans-stenotic pressure gradient"
        ],
        "venue": "Postepy w Kardiologii Interwencyjnej",
        "year": 2014,
        "id": "ytaVZoJb"
    },
    "BlHAAujs": {
        "authors": [
            {
                "name": "Xun Kou",
                "org": ""
            },
            {
                "name": "Yu Han",
                "org": ""
            },
            {
                "name": "Di Yang",
                "org": ""
            },
            {
                "name": "Yukai Liu",
                "org": ""
            },
            {
                "name": "Jinjuan Fu",
                "org": ""
            },
            {
                "name": "Shuo Zheng",
                "org": ""
            },
            {
                "name": "Duofen He",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Chunyu Zeng",
                "org": ""
            }
        ],
        "title": "Dopamine d1-like receptors suppress proliferation of vascular smooth muscle cell induced by insulin-like growth factor-1",
        "abstract": "Objective: Proliferation of vascular smooth muscle cells (VSMCs) participates in the pathogenesis and development of cardiovascular diseases, including essential hypertension and atherosclerosis. Our previous study found that stimulation of D1-like dopamine receptors inhibited insulin-induced proliferation of VSMCs. Insulin-like growth factor-1 (IGF-1) and insulin share similar structure and biological effect. However, whether or not there is any effect of D1-like receptors on IGF-1-induced proliferation of VSMCs is not known. Therefore, we investigated the inhibitory effect of D1-like dopamine receptors on the IGF-1-induced VSMCs proliferation in this study. Method: VSMC proliferation was determined by [",
        "keywords": [
            "Dopamine receptor",
            "Hypertension",
            "Insulin-like growth factor-1",
            "Proliferation",
            "Vascular smooth muscle cells"
        ],
        "venue": "Clinical and Experimental Hypertension",
        "year": 2014,
        "id": "BlHAAujs"
    },
    "XBmuHMzF": {
        "authors": [
            {
                "name": "Zhiwei Li",
                "org": "Department of Surgery, First Affiliated Hospital, Zhejiang University"
            },
            {
                "name": "Zhenhua Hu",
                "org": "Department of Surgery, First Affiliated Hospital, Zhejiang University"
            },
            {
                "name": "Jie Xiang",
                "org": "Department of Surgery, First Affiliated Hospital, Zhejiang University"
            },
            {
                "name": "Jie Zhou",
                "org": "Department of Surgery, First Affiliated Hospital, Zhejiang University"
            },
            {
                "name": "Sheng Yan",
                "org": "Department of Surgery, First Affiliated Hospital, Zhejiang University"
            },
            {
                "name": "Jian Wu",
                "org": "Department of Surgery, First Affiliated Hospital, Zhejiang University"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Surgery, First Affiliated Hospital, Zhejiang University"
            },
            {
                "name": "Shusen Zheng",
                "org": "Department of Surgery, First Affiliated Hospital, Zhejiang University"
            }
        ],
        "title": "Use of hepatitis B surface antigen-positive grafts in liver transplantation: A matched analysis of the US National database",
        "keywords": [
            ""
        ],
        "venue": "Liver Transplantation",
        "year": 2014,
        "id": "XBmuHMzF"
    },
    "3GXgoG2R": {
        "authors": [
            {
                "name": "Jian Zhou",
                "org": "Department of Otolaryngology, Eye, Ear, Nose and Throat Hospital, Fudan University"
            },
            {
                "name": "Duo Zhang",
                "org": "Department of Otolaryngology, Eye, Ear, Nose and Throat Hospital, Fudan University"
            },
            {
                "name": "Bin Chen",
                "org": "Department of Otolaryngology, Eye, Ear, Nose and Throat Hospital, Fudan University"
            },
            {
                "name": "Qing Li",
                "org": "Shanghai Institute of Immunology, Shanghai Jiaotong University School of Medicine"
            },
            {
                "name": "Lin Zhou",
                "org": "Shanghai Institute of Immunology, Shanghai Jiaotong University School of Medicine"
            },
            {
                "name": "Fei Liu",
                "org": "Shanghai Institute of Immunology, Shanghai Jiaotong University School of Medicine"
            },
            {
                "name": "Kuang-Yen Chou",
                "org": "Shanghai Institute of Immunology, Shanghai Jiaotong University School of Medicine"
            },
            {
                "name": "Lei Tao",
                "org": "Department of Otolaryngology, Eye, Ear, Nose and Throat Hospital, Fudan University"
            },
            {
                "name": "Li-Ming Lu",
                "org": "Shanghai Institute of Immunology, Shanghai Jiaotong University School of Medicine"
            }
        ],
        "title": "Association of interleukin-10 promoter polymorphisms and corresponding plasma levels with susceptibility to laryngeal squamous cell carcinoma",
        "keywords": [
            "Cytokines",
            "Interleukin-10",
            "Laryngeal squamous cell carcinoma",
            "Polymorphism",
            "Vocal leukoplakia"
        ],
        "venue": "Oncology Letters",
        "year": 2014,
        "id": "3GXgoG2R"
    },
    "vDZFn6hA": {
        "authors": [
            {
                "name": "Bin Jiao",
                "org": "Department of Neurology, Xiangya Hospital, Central South University"
            },
            {
                "name": "Beisha Tang",
                "org": "Key Laboratory of Hunan Province in Neurodegenerative Disorders, Central South University"
            },
            {
                "name": "Xiaoyan Liu",
                "org": "Department of Neurology, Xiangya Hospital, Central South University"
            },
            {
                "name": "Jun Xu",
                "org": "Department of Neurology, Jiangsu Geriatric Hospital"
            },
            {
                "name": "Yanjiang Wang",
                "org": "Department of Neurology and Center for Clinical Neuroscience, Daping Hospital, Third Military Medical University"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Hunan Province in Neurodegenerative Disorders, Central South University"
            },
            {
                "name": "Fufeng Zhang",
                "org": "Key Laboratory of Hunan Province in Neurodegenerative Disorders, Central South University"
            },
            {
                "name": "Xinxiang Yan",
                "org": "Key Laboratory of Hunan Province in Neurodegenerative Disorders, Central South University"
            },
            {
                "name": "Yafang Zhou",
                "org": "Key Laboratory of Hunan Province in Neurodegenerative Disorders, Central South University"
            },
            {
                "name": "Lu Shen",
                "org": "Key Laboratory of Hunan Province in Neurodegenerative Disorders, Central South University"
            }
        ],
        "title": "Mutational analysis in early-onset familial Alzheimer's disease inMainland China",
        "abstract": "Mutations of 3 causative genes, namely presenilin 1 (PSEN1), presenilin 2 (PSEN2), and amyloid precursor protein (APP), have been identified as the major causes of early-onset familial Alzheimer's disease (EOFAD). Recently, a GGGGCC repeat expansion in the noncoding region of C9orf72 was also detected in some patients with clinically diagnosed familial Alzheimer's disease. The prevalence of causative gene mutations in patients with EOFAD has been reported in previous studies but their prevalence remains unclear in Mainland China. The aim of this study was to characterize the common causative gene mutation spectrum and genotype-phenotype correlations in Chinese patients with EOFAD. Genetic screening for mutations in PSEN1, PSEN2, and APP was conducted in a total of 32 families with clinical diagnoses of EOFAD from Mainland China. Subsequently, a hexanucleotide repeat expansion in C9orf72 was detected in all patients. Four novel mutations in PSEN1 (p.A434T, p.I167del, p.F105C, and p.L248P) were identified in 4 respective families, and 1 previously recognized pathogenic mutation in APP (p.V717I) was detected in another 2 unrelated families. The PSEN2 mutation and pathogenic repeat expansions of C9orf72 were not detected in all patients. To the best of our knowledge, this is the first cohort report of a causative gene screen in patients with EOFAD in Mainland China. The analysis of the genetic-clinical correlations in this cohort supports the idea that the clinical phenotype might be influenced by specific genetic defects. \u00a9 2014 Elsevier Inc.",
        "keywords": [
            "APP",
            "C9orf72",
            "Early-onset familial Alzheimer's disease",
            "Mutation",
            "PSEN1",
            "PSEN2"
        ],
        "venue": "Neurobiology of Aging",
        "year": 2014,
        "id": "vDZFn6hA"
    },
    "gcU8K8sn": {
        "authors": [
            {
                "name": "Di Lu",
                "org": ""
            },
            {
                "name": "Xiao Xu",
                "org": ""
            },
            {
                "name": "Jianguo Wang",
                "org": ""
            },
            {
                "name": "Qi Ling",
                "org": ""
            },
            {
                "name": "Haiyang Xie",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Sheng Yan",
                "org": ""
            },
            {
                "name": "Weilin Wang",
                "org": ""
            },
            {
                "name": "Min Zhang",
                "org": ""
            },
            {
                "name": "Yan Shen",
                "org": ""
            },
            {
                "name": "Shusen Zheng",
                "org": ""
            }
        ],
        "title": "The influence of a contemporaneous portal and hepatic artery revascularization protocol on biliary complications after liver transplantation",
        "abstract": "Background. We sought to compare the impact of sequential and contemporaneous revascularizations of portal vein and hepatic artery on biliary complications in patients undergoing liver transplantation. Methods. We reviewed 184 patients who underwent liver transplantation in our center, and categorized them into different groups based on the duration of time between the portal venous and hepatic arterial reperfusion: >10 minutes in the sequential portal and hepatic artery revascularization group (SPA; n = 56), and within 1 minute in the contemporaneous portal and hepatic artery revascularization group (CPA; n = 121).The other patients with an interval from 1-10 minutes (n = 7) were excluded. This study then compared the outcomes between the SPA and CPA groups. Results. Cold ischemic time (mean \u00b1 standard deviation) for the SPA and CPA groups were 561 \u00b1 150 vs 577 \u00b1 187 minutes, respectively (P = .53). The incidence of biliary complications for the SPA and CPA groups were 14/56 and 11/121, respectively (25% vs 9%; P = .005). By the Clavien-Dindo Classification of Surgical Complications, the biliary complications in SPA group tended to be more severe compared with the CPA group (grade I, 0% vs 0%; II, 14% vs 36%; IIIa, 71% vs 64%; IIIb, 7% vs 0%; IV, 7% vs 0%; P = .10). Among biliary complications, the incidence of nonanatomic strictures was greater in the SPA group (9% vs 2%; P = .03), whereas the difference was not significant for anastomotic strictures (P = .054). Except for a lower serum albumin level in the SPA group 1 day after liver transplantation (P < .001), there are no differences in post-transplant liver function or renal function at 1, 7, and 30 days after transplantation. Conclusion. The CPA protocol can decrease the incidence of biliary complications substantially after liver transplantation and should replace the SPA protocol used by some centers in liver transplantation. \u00a9 2014 Mosby, Inc. All rights reserved.",
        "keywords": [
            ""
        ],
        "venue": "Surgery (United States)",
        "year": 2014,
        "id": "gcU8K8sn"
    },
    "ZBxHhnUe": {
        "authors": [
            {
                "name": "Xinhua Chen",
                "org": "Department of Hepatobiliary and Pancreatic Surgery, School of Medicine, Zhejiang University"
            },
            {
                "name": "Shengyong Yin",
                "org": "Department of Hepatobiliary and Pancreatic Surgery, School of Medicine, Zhejiang University"
            },
            {
                "name": "Chen Hu",
                "org": "Department of Hepatobiliary and Pancreatic Surgery, School of Medicine, Zhejiang University"
            },
            {
                "name": "Xinmei Chen",
                "org": "Department of Pharmacy, Shandong Traditional Chinese Medicine University"
            },
            {
                "name": "Kai Jiang",
                "org": "Colleges of Biomedical Engineering and Instrument Science, Zhejiang University"
            },
            {
                "name": "Shuming Ye",
                "org": "Colleges of Biomedical Engineering and Instrument Science, Zhejiang University"
            },
            {
                "name": "Xiaowen Feng",
                "org": "Department of Hepatobiliary and Pancreatic Surgery, School of Medicine, Zhejiang University"
            },
            {
                "name": "Shifeng Fan",
                "org": "Xinjiang Nanosecond Pulse Technology Institute"
            },
            {
                "name": "Haiyang Xie",
                "org": "Department of Hepatobiliary and Pancreatic Surgery, School of Medicine, Zhejiang University"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Hepatobiliary and Pancreatic Surgery, School of Medicine, Zhejiang University"
            },
            {
                "name": "Shusen Zheng",
                "org": "Department of Hepatobiliary and Pancreatic Surgery, School of Medicine, Zhejiang University"
            }
        ],
        "title": "Comparative study of nanosecond electric fields in vitro and in vivo on hepatocellular carcinoma indicate macrophage infiltration contribute to tumor ablation in vivo",
        "abstract": "Background and Aim: Recurrence and metastasis are associated with poor prognosis in hepatocellular carcinoma even in the patients who have undergone radical resection. Therefore, effective treatment is urgently needed for improvement of patients' survival. Previously, we reported that nanosecond pulse electric fields (nsPEFs) can ablate melanoma by induction of apoptosis and inhibition of angiogenesis. This study aims to investigate the in vivo ablation strategy by comparing the dose effect of nanosecond electric fields in vitro and in vivo on hepatocellular carcinoma. Materials and Methods: Four hepatocellular carcinoma cell lines HepG2, SMMC7721, Hep1-6, and HCCLM3 were pulsed to test the anti-proliferation and anti-migration ability of 100 ns nsPEFs in vitro. The animal model of human subdermal xenograft HCCLM3 cells into BALB/c nude mouse was used to test the anti-tumor growth and macrophage infiltration in vivo. Results: In vitro assays showed anti-tumor effect of nsPEFs is dose-dependant. But the in vivo study showed the strategy of low dose and multiple treatments is superior to high dose single treatment. The macrophages infiltration significantly increased in the tumors which were treated by multiple low dose nsPEFs. Conclusion: The low dose multiple nsPEFs application is more efficient than high dose single treatment in inhibiting the tumor volume in vivo, which is quite different from the dose-effect relationship in vitro. Beside the electric field strength, the macrophage involvement must be considered to account for effect variability and toxicology in vivo. \u00a9 2014 Chen et al.",
        "keywords": [
            ""
        ],
        "venue": "PLoS ONE",
        "year": 2014,
        "id": "ZBxHhnUe"
    },
    "n0IgJfcd": {
        "authors": [
            {
                "name": "Sunyi Ye",
                "org": ""
            },
            {
                "name": "Chenxi Zhang",
                "org": ""
            },
            {
                "name": "Jie Zhou",
                "org": ""
            },
            {
                "name": "Jun Cheng",
                "org": ""
            },
            {
                "name": "Zhen Lv",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Haiyang Xie",
                "org": ""
            },
            {
                "name": "Jian Wu",
                "org": ""
            },
            {
                "name": "Shusen Zheng",
                "org": ""
            }
        ],
        "title": "Human heat shock protein 27 exacerbates ischemia reperfusion injury in rats by reducing the number of T regulatory cells",
        "keywords": [
            "Heat shock protein 27",
            "Ischemic reperfusion injury",
            "Liver",
            "Regulatory T cells"
        ],
        "venue": "Molecular Medicine Reports",
        "year": 2014,
        "id": "n0IgJfcd"
    },
    "mHV4oc3Y": {
        "authors": [
            {
                "name": "Zhiyun Zheng",
                "org": ""
            },
            {
                "name": "Sheng Gao",
                "org": ""
            },
            {
                "name": "Zhe Yang",
                "org": ""
            },
            {
                "name": "Haiyang Xie",
                "org": ""
            },
            {
                "name": "Cheng Zhang",
                "org": ""
            },
            {
                "name": "Bingyi Lin",
                "org": ""
            },
            {
                "name": "Liming Wu",
                "org": ""
            },
            {
                "name": "Shusen Zheng",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            }
        ],
        "title": "Single nucleotide polymorphisms in the metastasisassociated in colon cancer-1 gene predict the recurrence of hepatocellular carcinoma after transplantation",
        "abstract": "Background: The newly identified metastasis-associated in colon cancer-1 (MACC1) gene is involved in angiogenesis, epithelial-to-mesenchymal transition (EMT), invasiveness, and metastasis in a variety of malignancies. Overexpression of MACC1 gene is a prognostic marker for poor outcome of hepatocellular carcinoma (HCC) patients. However, the association between genetic polymorphisms of MACC1 gene and poor outcome in HCC has been not been performed. We therefore investigated the correlation of MACC1 single nucleotide polymorphisms (SNPs) with tumor recurrence and overall survival in HCC patients undergoing liver transplantation (LT). Methods: The study included 187 HCC patients treated with LT. Five polymorphisms in the MACC1 gene (rs1990172, rs3735615, rs4721888, rs2241056, rs975263) were genotyped in 183 cases of tumorous tissue sample and 117 cases of adjacent normal tissue sample using SNaP-Shot assays. The association of SNPs with tumor recurrence and overall survival was then analyzed by additive, dominant, recessive, and overdominant models in a cohort of 156 HCC patients. Results: In terms of tumor recurrence, heterozygous of SNP rs1990172 and SNP rs975263 showed a significant high risk of relapse using univariate and multivariate analysis (overdominant, HR(95%CI)=2.27 [1.41-3.66], P=0.001; HR(95%CI)=2.16 [1.37-3.39], P=0.001). But the difference between heterozygous of these two SNPs and overall survival did not reach a significance in all models. The other three investigated SNPs were not significantly associated with tumor recurrence and overall survival (P>0.05). In addition, we found no significant difference in genotype frequencies between HCC and controls. Conclusions: Our data suggest that SNP rs1990172 and SNP rs975263 in the MACC1 gene may be potential genetic markers for HCC recurrence in LT patients. \u00a9 Ivyspring International Publisher.",
        "keywords": [
            "Epithelial-to-mesenchymal transition",
            "Metastasis-associated in colon cancer-1"
        ],
        "venue": "International Journal of Medical Sciences",
        "year": 2014,
        "id": "mHV4oc3Y"
    },
    "qZXBf3PV": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Department of Gastroenterology, 88th Hospital of PLA"
            },
            {
                "name": "Yulong Shang",
                "org": "State Key Laboratory of Cancer Biology, Xijing Hospital of Digestive Diseases, Fourth Military Medical University"
            },
            {
                "name": "Changhao Liu",
                "org": "State Key Laboratory of Cancer Biology, Xijing Hospital of Digestive Diseases, Fourth Military Medical University"
            },
            {
                "name": "Jinge Li",
                "org": "State Key Laboratory of Cancer Biology, Xijing Hospital of Digestive Diseases, Fourth Military Medical University"
            },
            {
                "name": "Hao Hu",
                "org": "State Key Laboratory of Cancer Biology, Xijing Hospital of Digestive Diseases, Fourth Military Medical University"
            },
            {
                "name": "Cong Liang",
                "org": "State Key Laboratory of Cancer Biology, Xijing Hospital of Digestive Diseases, Fourth Military Medical University"
            },
            {
                "name": "Yanan Han",
                "org": "Department of Gastroenterology, Xi'an Children's Hospital"
            },
            {
                "name": "Wei Zhang",
                "org": "Department of Gastroenterology, 88th Hospital of PLA"
            },
            {
                "name": "Jie Liang",
                "org": "State Key Laboratory of Cancer Biology, Xijing Hospital of Digestive Diseases, Fourth Military Medical University"
            },
            {
                "name": "Kaichun Wu",
                "org": "State Key Laboratory of Cancer Biology, Xijing Hospital of Digestive Diseases, Fourth Military Medical University"
            }
        ],
        "title": "Overexpression of PrPc, combined with MGr1-Ag/37LRP, is predictive of poor prognosis in gastric cancer",
        "abstract": "Prion protein (PrPc) has been previously reported to be involved in gastric cancer (GC) development and progression. However, the association between expression of PrPc and GC prognosis is yet poorly characterized. In the present study, the expressions of PrPc and MGr1-Ag/37LRP, a protein interacting with PrPc, were detected using the tissue microarray technique and immunohistochemical method to compare clinicopathological parameters of 238 GC patients. We found that the expressions of PrPc and MGr1-Ag/37LRP were upregulated in GC lesions compared with their expressions in adjacent noncancerous tissues (p < 0.01). High expression of PrPc was detected in 37.39% (89/238) of GC patients and positively correlated with the expression of MGr1-Ag/37LRP (r 5 0.532, p < 0.001). PrPc expression was associated with a number of clinicopathological parameters including depth of invasion and lymph node metastasis of the tumor (p < 0.001). High expression of PrPc brought a poorer prognosis than low PrPc expression. Moreover, GC patients with high level of PrPc and high level of MGr1-Ag/37LRP had the poorest prognosis. Multivariate survival analysis suggested that, along with other parameters, combined expression of PrPc and MGr1-Ag/37LRP was independent prognostic factors for GC patients. These data indicates that overexpression of PrPc, combined with MGr1-Ag/37LRP, is predictive of poor prognosis in GC and thereby could be used to guide the clinical decision.",
        "keywords": [
            "Gastric cancer",
            "MGr1-Ag/37LRP",
            "Prognosis",
            "PrPc"
        ],
        "venue": "International Journal of Cancer",
        "year": 2014,
        "id": "qZXBf3PV"
    },
    "2eiM65rI": {
        "authors": [
            {
                "name": "Jun Cheng",
                "org": "Key Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health, Zhejiang University"
            },
            {
                "name": "Feng Gao",
                "org": "Department of General Surgery, The Second Hospital, Shanxi Medical University"
            },
            {
                "name": "Xiang Chen",
                "org": "Shanghai Key Laboratory of Agricultural Genetics and Breeding, Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences"
            },
            {
                "name": "Jian Wu",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University"
            },
            {
                "name": "Chunyang Xing",
                "org": "Key Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health, Zhejiang University"
            },
            {
                "name": "Zhen Lv",
                "org": "Key Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health, Zhejiang University"
            },
            {
                "name": "Wei Xu",
                "org": "State Key Laboratory of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University"
            },
            {
                "name": "Qing Xie",
                "org": "State Key Laboratory of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University"
            },
            {
                "name": "Liming Wu",
                "org": "Key Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health, Zhejiang University"
            },
            {
                "name": "Sunyi Ye",
                "org": "Key Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health, Zhejiang University"
            },
            {
                "name": "Haiyang Xie",
                "org": "Key Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health, Zhejiang University"
            },
            {
                "name": "Shusen Zheng",
                "org": "Key Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health, Zhejiang University"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health, Zhejiang University"
            }
        ],
        "title": "Prohibitin-2 promotes hepatocellular carcinoma malignancy progression in hypoxia based on a label-free quantitative proteomics strategy",
        "keywords": [
            "Biomarker",
            "Hepatocellular carcinoma",
            "Label-free",
            "Prohibitin-2",
            "Proteomics"
        ],
        "venue": "Molecular Carcinogenesis",
        "year": 2014,
        "id": "2eiM65rI"
    },
    "kBtrA96U": {
        "authors": [
            {
                "name": "Xinquan Wang",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Hao Luo",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Caiyu Chen",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Ken Chen",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Jialiang Wang",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Yue Cai",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Shuo Zheng",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Xiaoli Yang",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Lin Zhou",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Pedro A. Jose",
                "org": "Department of Physiology, University of Maryland, School of Medicine"
            },
            {
                "name": "Chunyu Zeng",
                "org": "Chongqing Institute of Cardiology"
            }
        ],
        "title": "Prenatal lipopolysaccharide exposure results in dysfunction of the renal dopamine D",
        "abstract": "Adverse environment in early life can modulate the adult phenotype, including blood pressure. Lipopolysaccharide (LPS) exposure in utero results in increased blood pressure in the offspring, but the exact mechanisms are not clear. Studies have shown that the renal dopamine D",
        "keywords": [
            "D dopamine receptor",
            "Fetal programming",
            "G protein-coupledreceptorkinase",
            "Hypertension",
            "Lipopolysaccharide",
            "Oxidativestress",
            "TEMPOL"
        ],
        "venue": "Free Radical Biology and Medicine",
        "year": 2014,
        "id": "kBtrA96U"
    },
    "aVqkt9t6": {
        "authors": [
            {
                "name": "Sheng Gao",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Bing-Yi Lin",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Zhe Yang",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Zhi-Yun Zheng",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Zhi-Kun Liu",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Li-Ming Wu",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Hai-Yang Xie",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Division of Hepatobiliary and Pancreatic Surgery"
            }
        ],
        "title": "Role of overexpression of MACC1 and/or FAK in predicting prognosis of hepatocellular carcinoma after liver transplantation",
        "abstract": "Background: Metastasis-associated in colon cancer-1 (MACC1) acts as a promoter of tumor metastasis; however, the predictive value of MACC1 for hepatocellular carcinoma (HCC) after liver transplantation (LT) remains unclear. Methods: We examined the expression of MACC1 and its target genes MET and FAK by quantitative PCR in 160 patients with HCC that was undergone LT. Results: The patients with MACC1",
        "keywords": [
            "Hepatocellular carcinoma",
            "Liver transplantation",
            "Metastasis",
            "Metastasis-associated in colon cancer-1",
            "Prognosis"
        ],
        "venue": "International Journal of Medical Sciences",
        "year": 2014,
        "id": "aVqkt9t6"
    },
    "tQDwH2ib": {
        "authors": [
            {
                "name": "Heng Xiao",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Rongliang Tong",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Shaobing Cheng",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Zhen Lv",
                "org": "Department of Surgery, First Affiliated Hospital, Zhejiang University School of Medicine"
            },
            {
                "name": "Chaofeng Ding",
                "org": "Department of Surgery, First Affiliated Hospital, Zhejiang University School of Medicine"
            },
            {
                "name": "Chengli Du",
                "org": "Department of Surgery, First Affiliated Hospital, Zhejiang University School of Medicine"
            },
            {
                "name": "Haiyang Xie",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Jian Wu",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Shusen Zheng",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            }
        ],
        "title": "BAG3 and HIF-1 \u03b1 coexpression detected by immunohistochemistry correlated with prognosis in hepatocellular carcinoma after liver transplantation",
        "keywords": [
            ""
        ],
        "venue": "BioMed Research International",
        "year": 2014,
        "id": "tQDwH2ib"
    },
    "9Abf88bL": {
        "authors": [
            {
                "name": "Yu Mao",
                "org": "Division of Cardiology, Tongji Hospital, Tongji University School of Medicine"
            },
            {
                "name": "Xiaolong Qi",
                "org": "Tongji Hospital, Tongji University School of Medicine"
            },
            {
                "name": "Wei Xu",
                "org": "Tongji Hospital, Tongji University School of Medicine"
            },
            {
                "name": "Lin Zhou",
                "org": "Division of Cardiology, Tongji Hospital, Tongji University School of Medicine"
            }
        ],
        "title": "Renal fractional flow reserve: Is it available to predict hypertension improvement after stenting?",
        "abstract": "",
        "keywords": [
            ""
        ],
        "venue": "Cardiology Journal",
        "year": 2014,
        "id": "9Abf88bL"
    },
    "ww1RyV09": {
        "authors": [
            {
                "name": "Zhenhua Hu",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, School of Medicine, Zhejiang University, Key Laboratory of Combined Multi-organ Transplantation Ministry of Public Health Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Zhiwei Li",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, School of Medicine, Zhejiang University, Key Laboratory of Combined Multi-organ Transplantation Ministry of Public Health Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Jie Xiang",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, School of Medicine, Zhejiang University, Key Laboratory of Combined Multi-organ Transplantation Ministry of Public Health Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Jie Zhou",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, School of Medicine, Zhejiang University, Key Laboratory of Combined Multi-organ Transplantation Ministry of Public Health Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Sheng Yan",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, School of Medicine, Zhejiang University, Key Laboratory of Combined Multi-organ Transplantation Ministry of Public Health Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Jian Wu",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, School of Medicine, Zhejiang University, Key Laboratory of Combined Multi-organ Transplantation Ministry of Public Health Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Lin Zhou",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, School of Medicine, Zhejiang University, Key Laboratory of Combined Multi-organ Transplantation Ministry of Public Health Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Shusen Zheng",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, School of Medicine, Zhejiang University, Key Laboratory of Combined Multi-organ Transplantation Ministry of Public Health Key Laboratory of Organ Transplantation"
            }
        ],
        "title": "Intent-to-Treat Analysis of Liver Transplant for Hepatocellular Carcinoma in the MELD Era: Impact of Hepatitis C and Advanced Status",
        "keywords": [
            "Liver transplantation",
            "Patient selection",
            "Primary hepatic malignancy",
            "Registry",
            "Waiting list"
        ],
        "venue": "Digestive Diseases and Sciences",
        "year": 2014,
        "id": "ww1RyV09"
    },
    "wg4NCHpT": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine"
            },
            {
                "name": "Fei Liu",
                "org": "Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine"
            },
            {
                "name": "Guang-Yan Zhou",
                "org": "Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine"
            },
            {
                "name": "Li-Ming Lu",
                "org": "Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine"
            }
        ],
        "title": "Effects of trichosanthin on apoptosis and proliferation of colorectal cancer cell line CMT-93",
        "keywords": [
            "Cell apoptosis",
            "Cell proliferation",
            "Colorectal cancer",
            "Trichosanthin"
        ],
        "venue": "Journal of Shanghai Jiaotong University (Medical Science)",
        "year": 2014,
        "id": "wg4NCHpT"
    },
    "dlOLPO3n": {
        "authors": [
            {
                "name": "Liang Zhou",
                "org": "Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University School of Medicine"
            },
            {
                "name": "Chong-Yu Shao",
                "org": "Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University School of Medicine"
            },
            {
                "name": "Si-min Xu",
                "org": "Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University School of Medicine"
            },
            {
                "name": "Jiao Ma",
                "org": "Department of Neurobiology, Center of Scientific Technology, Cranial Cerebral Disease Lab, Ningxia Medical University"
            },
            {
                "name": "Ya-Jun Xie",
                "org": "Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University School of Medicine"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University School of Medicine"
            },
            {
                "name": "Peng Teng",
                "org": "Institute of Developmental and Regenerative Biology, College of Life and Environmental Science, Hangzhou Normal University"
            },
            {
                "name": "Yin Wang",
                "org": "Department of Neurobiology, Center of Scientific Technology, Cranial Cerebral Disease Lab, Ningxia Medical University"
            },
            {
                "name": "Mengsheng Qiu",
                "org": "Institute of Developmental and Regenerative Biology, College of Life and Environmental Science, Hangzhou Normal University"
            },
            {
                "name": "Ying Shen",
                "org": "Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University School of Medicine"
            }
        ],
        "title": "GSK3\u03b2 Promotes the Differentiation of Oligodendrocyte Precursor Cells via \u03b2-Catenin-Mediated Transcriptional Regulation",
        "keywords": [
            "Differentiation",
            "GSK3\u03b2",
            "Myelination",
            "Oligodendrocyte",
            "Transcription factor"
        ],
        "venue": "Molecular Neurobiology",
        "year": 2014,
        "id": "dlOLPO3n"
    },
    "M9ELdDM2": {
        "authors": [
            {
                "name": "Zhigang Ren",
                "org": "Department of Hepatobiliary and Pancreatic Surgery, First Affiliated Hospital, Zhejiang University"
            },
            {
                "name": "Jianwen Jiang",
                "org": "Department of Hepatobiliary and Pancreatic Surgery, First Affiliated Hospital, Zhejiang University"
            },
            {
                "name": "Haifeng Lu",
                "org": "State Key Laboratory for Diagnosis and Treatment of Infectious Disease, First Affiliated Hospital, Zhejiang University"
            },
            {
                "name": "Xinhua Chen",
                "org": "Department of Hepatobiliary and Pancreatic Surgery, First Affiliated Hospital, Zhejiang University"
            },
            {
                "name": "Yong He",
                "org": "Department of Hepatobiliary and Pancreatic Surgery, First Affiliated Hospital, Zhejiang University"
            },
            {
                "name": "Hua Zhang",
                "org": "State Key Laboratory for Diagnosis and Treatment of Infectious Disease, First Affiliated Hospital, Zhejiang University"
            },
            {
                "name": "Haiyang Xie",
                "org": "Department of Hepatobiliary and Pancreatic Surgery, First Affiliated Hospital, Zhejiang University"
            },
            {
                "name": "Weilin Wang",
                "org": "Department of Hepatobiliary and Pancreatic Surgery, First Affiliated Hospital, Zhejiang University"
            },
            {
                "name": "Shusen Zheng",
                "org": "Department of Hepatobiliary and Pancreatic Surgery, First Affiliated Hospital, Zhejiang University"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Hepatobiliary and Pancreatic Surgery, First Affiliated Hospital, Zhejiang University"
            }
        ],
        "title": "Intestinal microbial variation may predict early acute rejection after liver transplantation in rats",
        "abstract": "Background. Acute rejection (AR) remains a life-threatening complication after orthotopic liver transplantation (OLT) and there are few available diagnostic biomarkers clinically for AR. This study aims to identify intestinal microbial profile and explore potential application of microbial profile as a biomarker for AR after OLT. Methods. The OLT models in rats were established. Hepatic graft histology, ultrastructure, function, and intestinal barrier function were tested. Ileocecal contents were collected for intestinal microbial analysis. Results. Hepatic graft suffered from the ischemia-reperfusion (I/R) injury on day 1, initial AR on day 3, and severe AR on day 7 after OLT. Real-time quantitative polymerase chain reaction results showed that genus Faecalibacterium prausnitzii and Lactobacillus were decreased, whereas Clostridium bolteae was increased during AR. Notably, cluster analysis of denaturing gradient gel electrophoresis (DGGE) profiles showed the 7AR and 3AR groups clustered together with 73.4% similarity, suggesting that intestinal microbiota was more sensitive than hepatic function in responding to AR. Microbial diversity and species richness were decreased during AR. Phylogenetic tree analysis showed thatmost of the decreased key bacteria belonged to phylum Firmicutes, whereas increased key bacteria belonged to phylum Bacteroidetes.Moreover, intestinal microvilli loss and tight junction damage were noted, and intestinal barrier dysfunction during AR presented a decrease of fecal secretory immunoglobulin A (sIgA) and increase of blood bacteremia, endotoxin, and tumor necrosis factor-. Conclusion. We dynamically detail intestinal microbial characterization and find a high sensitivity of microbial change during AR after OLT, suggesting that intestinal microbial variation may predict AR in early phase and become an assistant therapeutic target to improve rejection after OLT.",
        "keywords": [
            "Acute rejection",
            "Intestinal microbiota",
            "Liver transplantation",
            "Microbiota-liver axis"
        ],
        "venue": "Transplantation",
        "year": 2014,
        "id": "M9ELdDM2"
    },
    "sd68e9GK": {
        "authors": [
            {
                "name": "Chuanhui Peng",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Zhijun Zhang",
                "org": "Department of Surgery, Zhejiang University, First Affiliated Hospital"
            },
            {
                "name": "Jian Wu",
                "org": "Department of Surgery, Zhejiang University, First Affiliated Hospital"
            },
            {
                "name": "Zhen Lv",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Jie Tang",
                "org": "Department of Surgery, Zhejiang University, First Affiliated Hospital"
            },
            {
                "name": "Haiyang Xie",
                "org": "Department of Surgery, Zhejiang University, First Affiliated Hospital"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Surgery, Zhejiang University, First Affiliated Hospital"
            },
            {
                "name": "Shusen Zheng",
                "org": "Department of Surgery, Zhejiang University, First Affiliated Hospital"
            }
        ],
        "title": "A critical role for ZDHHC2 in metastasis and recurrence in human hepatocellular carcinoma",
        "keywords": [
            ""
        ],
        "venue": "BioMed Research International",
        "year": 2014,
        "id": "sd68e9GK"
    },
    "OYqrsiJe": {
        "authors": [
            {
                "name": "Xiao Xu",
                "org": "Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases"
            },
            {
                "name": "Hai-Jun Guo",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Hai-Yang Xie",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Jie Li",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Run-Zhou Zhuang",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Qi Ling",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Xu-Yong Wei",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Zhi-Kun Liu",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Song-Ming Ding",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Kang-Jie Chen",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Zhi-Yuan Xu",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases"
            }
        ],
        "title": "ZIP4, a novel determinant of tumor invasion in hepatocellular carcinoma, contributes to tumor recurrence after liver transplantation",
        "abstract": "Background and purpose: Recently, evidence that Zinc transporter ZRT/IRT-like protein 4 (ZIP4) is involved in invasiveness and apoptosis has emerged in pancreatic cancer and prostate cancer. Our aim was to assess the role of ZIP4 in invasiveness, migration and apoptosis of hepatocellular carcinoma (HCC). The prognostic value of ZIP4 in HCC after liver transplantation was evaluated. Methods: The role of ZIP4 in HCC was investigated by overexpressing ZIP4 in BEL7402 and HepG2 cells and inhibiting ZIP4 in HuH-7 and HepG2 cells, using overexpression and shRNA plasmids in vitro studies. Immunohistochemical analysis was used to evaluate ZIP4 expression in HCC tissues from 60 patients undergoing liver transplantation, 36 cirrhotic tissue samples, and 6 normal tissue samples. Prognostic significance was assessed using the Kaplan-Meier method and the log-rank test. Results: Specific suppression of ZIP4 reduced cell migration and invasiveness, whereas ZIP4 overexpression caused increases in cell migration and invasiveness. Furthermore, overexpression of ZIP4 resulted in increased expression of pro-metastatic genes (MMP-2, MMP-9) and decreased expression of pro-apoptotic genes (caspase-3, caspase-9, Bax). In contrast, suppression of ZIP4 resulted in an opposite effect. ZIP4 was more highly expressed in tumor tissues than non-tumor tissues (P < 0.0001). ZIP4 expression was significantly associated with tumor recurrence (P = 0.002), tumor node metastasis stage (P = 0.044), Child-Turcotte-Pugh score (P = 0.042), and tumor size (P = 0.022). Univariate analysis showed that ZIP4 expression was significantly associated with overall survival (P = 0.020) and tumor-free survival (P = 0.049). Multivariate analysis revealed that ZIP4 was an independent predictor of overall survival (P = 0.037) after liver transplantation. Conclusions: ZIP4 could promote migration, invasiveness, and suppress apoptosis in hepatocellular carcinoma, and represent a novel predictor of poor prognosis and therapeutic target for patients with HCC who undergo liver transplantation. \u00a9 Ivyspring International Publisher.",
        "keywords": [
            "Hepatocellular carcinoma",
            "Liver transplantation",
            "ZIP4"
        ],
        "venue": "International Journal of Biological Sciences",
        "year": 2014,
        "id": "OYqrsiJe"
    },
    "Dt6gFMwN": {
        "authors": [
            {
                "name": "Xiaolong Qi",
                "org": ""
            },
            {
                "name": "Guoxin Fan",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Changqing Yang",
                "org": ""
            }
        ],
        "title": "Clinical implication landmark: Noninvasive quantification of fractional flow reserve evaluating interventional therapy",
        "abstract": "",
        "keywords": [
            ""
        ],
        "venue": "Catheterization and Cardiovascular Interventions",
        "year": 2014,
        "id": "Dt6gFMwN"
    },
    "nNRgTZgj": {
        "authors": [
            {
                "name": "Ken Chen",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Chunjiang Fu",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Caiyu Chen",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Li Liu",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Hongmei Ren",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Yu Han",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Jian Yang",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Duofen He",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Lin Zhou",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Zhiwei Yang",
                "org": "Peking Union Medical College"
            },
            {
                "name": "Lianfeng Zhang",
                "org": "Peking Union Medical College"
            },
            {
                "name": "Pedro A. Jose",
                "org": "Division of Nephrology"
            },
            {
                "name": "Chunyu Zeng",
                "org": "Chongqing Institute of Cardiology"
            }
        ],
        "title": "Role of GRK4 in the regulation of arterial AT1 receptor in hypertension",
        "abstract": "G-protein-coupled receptor kinase 4 (GRK4) gene variants, via impairment of renal dopamine receptor and enhancement of renin-angiotensin system functions, cause sodium retention and increase blood pressure. Whether GRK4 and the angiotensin type 1 receptor (AT1R) interact in the aorta is not known. We report that GRK4 is expressed in vascular smooth muscle cells of the aorta. Heterologous expression of the GRK4\u03b3 variant 142V in A10 cells increased AT1R protein expression and AT1R-mediated increase in intracellular calcium concentration. The increase in AT1R expression was related to an increase in AT1R mRNA expression via the NF-\u03baB pathway. As compared with control, cells expressing GRK4\u03b3 142V had greater NF-\u03baB activity with more NF-\u03baB bound to the AT1R promoter. The increased AT1R expression in cells expressing GRK4\u03b3 142V was also associated with decreased AT1R degradation, which may be ascribed to lower AT1R phosphorylation. There was a direct interaction between GRK4\u03b3 and AT1R that was decreased by GRK4\u03b3 142V. The regulation of AT1R expression by GRK4\u03b3 142V in A10 cells was confirmed in GRK4\u03b3 142V transgenic mice; AT1R expression was higher in the aorta of GRK4\u03b3 142V transgenic mice than control GRK4\u03b3 wild-type mice. Angiotensin II-mediated vasoconstriction of the aorta was also higher in GRK4\u03b3 142V than in wild-type transgenic mice. This study provides a mechanism by which GRK4, via regulation of arterial AT1R expression and function, participates in the pathogenesis of conduit vessel abnormalities in hypertension. \u00a9 2013 American Heart Association, Inc.",
        "keywords": [
            "angiotensin",
            "arteries",
            "G-protein-coupled receptor kinase 4",
            "hypertension",
            "receptor",
            "type 1"
        ],
        "venue": "Hypertension",
        "year": 2014,
        "id": "nNRgTZgj"
    },
    "CFx6mvI7": {
        "authors": [
            {
                "name": "De-Juan Wang",
                "org": "Department of Neurobiology"
            },
            {
                "name": "Li-Da Su",
                "org": "Neuroscience Care Unit"
            },
            {
                "name": "Ya-Nan Wang",
                "org": "Department of Neurobiology"
            },
            {
                "name": "Dong Yang",
                "org": "Department of Neurobiology"
            },
            {
                "name": "Cheng-Long Sun",
                "org": "Department of Neurobiology"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Neurobiology"
            },
            {
                "name": "Xin-Xin Wang",
                "org": "Department of Neurobiology"
            },
            {
                "name": "Ying Shen",
                "org": "Department of Neurobiology"
            }
        ],
        "title": "Long-term potentiation at cerebellar parallel fiber-Purkinje cell synapses requires presynaptic and postsynaptic signaling cascades",
        "abstract": "Long-term depression (LTD) and long-term potentiation (LTP) at cerebellar parallel fiber-Purkinje cell (PF-PC) synapses play critical roles in motor learning. The 1 Hz stimulation at PF-PC synapses induces a postsynaptically expressed LTP that requires a postsynaptic Ca",
        "keywords": [
            "Arachidonic acid",
            "cPLA2\u03b1",
            "Endocannabinoids",
            "Long-term potentiation",
            "Parallel fiber",
            "Purkinje cell"
        ],
        "venue": "Journal of Neuroscience",
        "year": 2014,
        "id": "CFx6mvI7"
    },
    "kZXh9Q0V": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Junjing Huang",
                "org": ""
            },
            {
                "name": "Jun Gao",
                "org": ""
            },
            {
                "name": "Guanpo Zhang",
                "org": ""
            },
            {
                "name": "Jinjin Jiang",
                "org": ""
            }
        ],
        "title": "NMDA and AMPA receptors in the anterior cingulate cortex mediates visceral pain in visceral hypersensitivity rats",
        "abstract": "Several studies have shown that N-methyl-. d-aspartate (NMDA)-receptor activation in anterior cingulate cortex (ACC) neurons plays critical roles in modulating visceral pain responses in visceral hypersensitivity (VH) rats. However, there are few reports about the expressions of NMDA and \u03b1-amino-3-hydroxy-5-methyl-4-isox-azolepropionic-acid (AMPA) receptor subtypes in ACC of VH model rats at different time points. The current study was undertaken to investigate NR2A, NR2B and GluR2 expressions in ACC of VH rats that were induced by administration with 5% mustard oil. Our results indicated that NR2B, but not NR2A, was highly expressed in VH model group on day 15, 22, and 36 compared with normal group (p<. 0.05). GluR2 expression was also higher in VH model group on day 15, 22, and 36 than that of normal group (p<. 0.05). These findings suggested increased expression of NR2B and GluR2 might be key mechanisms for long-term synaptic plastic changes in VH rats. \u00a9 2014.",
        "keywords": [
            "\u03b1-Amino-3-hydroxy-5-methyl-4-isox-azolepropionic-acid",
            "Anterior cingulate cortex",
            "N-methyl-d-aspartate",
            "Visceral hypersensitivity"
        ],
        "venue": "Cellular Immunology",
        "year": 2014,
        "id": "kZXh9Q0V"
    },
    "vmMQO05s": {
        "authors": [
            {
                "name": "Jian Zhou",
                "org": "Department of Otolaryngology"
            },
            {
                "name": "Fei Liu",
                "org": "Shanghai Institute of Immunology"
            },
            {
                "name": "Duo Zhang",
                "org": "Department of Otolaryngology"
            },
            {
                "name": "Bin Chen",
                "org": "Department of Otolaryngology"
            },
            {
                "name": "Qing Li",
                "org": "Shanghai Institute of Immunology"
            },
            {
                "name": "Lin Zhou",
                "org": "Shanghai Institute of Immunology"
            },
            {
                "name": "Li-Ming Lu",
                "org": "Shanghai Institute of Immunology"
            },
            {
                "name": "Lei Tao",
                "org": "Department of Otolaryngology"
            }
        ],
        "title": "Significance of MDM2-309 polymorphisms and induced corresponding plasma MDM2 levels in susceptibility to laryngeal squamous cell carcinoma",
        "keywords": [
            ""
        ],
        "venue": "DNA and Cell Biology",
        "year": 2014,
        "id": "vmMQO05s"
    },
    "ABhOEVc4": {
        "authors": [
            {
                "name": "Jinjuan Fu",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Yu Han",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Hongyong Wang",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Zhen Wang",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Yukai Liu",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Xingjian Chen",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Yue Cai",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Weiwei Guan",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Di Yang",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Laureano D. Asico",
                "org": "Division of Nephrology"
            },
            {
                "name": "Lin Zhou",
                "org": "Chongqing Institute of Cardiology"
            },
            {
                "name": "Pedro A. Jose",
                "org": "Department of Physiology"
            },
            {
                "name": "Chunyu Zeng",
                "org": "Chongqing Institute of Cardiology"
            }
        ],
        "title": "Impaired dopamine D1 receptor-mediated vasorelaxation of mesenteric arteries in obese Zucker rats",
        "abstract": "Background: Obesity plays an important role in the pathogenesis of hypertension. Renal dopamine D",
        "keywords": [
            "Dopamine D1 receptor",
            "Hyperglycemia",
            "Hyperinsulinemia",
            "Obese Zucker rats",
            "Obesity-related hypertension",
            "Vasorelaxation"
        ],
        "venue": "Cardiovascular Diabetology",
        "year": 2014,
        "id": "ABhOEVc4"
    },
    "PWbp660g": {
        "authors": [
            {
                "name": "Chaofeng Ding",
                "org": ""
            },
            {
                "name": "Shaobing Cheng",
                "org": ""
            },
            {
                "name": "Zhe Yang",
                "org": ""
            },
            {
                "name": "Zhen Lv",
                "org": ""
            },
            {
                "name": "Heng Xiao",
                "org": ""
            },
            {
                "name": "Chengli Du",
                "org": ""
            },
            {
                "name": "Chuanhui Peng",
                "org": ""
            },
            {
                "name": "Haiyang Xie",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Jian Wu",
                "org": ""
            },
            {
                "name": "Shusen Zheng",
                "org": ""
            }
        ],
        "title": "Long non-coding RNA HOTAIR promotes cell migration and invasion via down-regulation of RNA binding motif protein 38 in hepatocellular carcinoma cells",
        "keywords": [
            "Hepatocellular carcinoma",
            "HOX transcript antisense RNA",
            "Long non-coding RNA",
            "RNA binding motif protein 38"
        ],
        "venue": "International Journal of Molecular Sciences",
        "year": 2014,
        "id": "PWbp660g"
    },
    "Zp09hnBn": {
        "authors": [
            {
                "name": "Jun Chen",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital"
            },
            {
                "name": "Xiao Xu",
                "org": "Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases"
            },
            {
                "name": "Jian Wu",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital"
            },
            {
                "name": "Qi Ling",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital"
            },
            {
                "name": "Kai Wang",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital"
            },
            {
                "name": "Weilin Wang",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital"
            },
            {
                "name": "Min Zhang",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital"
            },
            {
                "name": "Yan Shen",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital"
            },
            {
                "name": "Lin Zhou",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital"
            },
            {
                "name": "Haiyang Xie",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital"
            },
            {
                "name": "Shusen Zheng",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital"
            }
        ],
        "title": "The stratifying value of hangzhou criteria in liver transplantation for hepatocellular carcinoma",
        "keywords": [
            ""
        ],
        "venue": "PLoS ONE",
        "year": 2014,
        "id": "Zp09hnBn"
    },
    "nNIWSTfI": {
        "authors": [
            {
                "name": "Renming Zhong",
                "org": "Department of Radiation Oncology, Cancer Center, West China School of Medicine/West China Hospital, Sichuan University"
            },
            {
                "name": "Jin Wang",
                "org": "Department of Thoracic Oncology, Cancer Center and State Key Laboratory of Biotherapy, West China School of Medicine/West China Hospital, Sichuan University"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Thoracic Oncology, Cancer Center and State Key Laboratory of Biotherapy, West China School of Medicine/West China Hospital, Sichuan University"
            },
            {
                "name": "Feng Xu",
                "org": "Department of Radiation Oncology, Cancer Center, West China School of Medicine/West China Hospital, Sichuan University"
            },
            {
                "name": "Li Liu",
                "org": "Department of Radiation Oncology, Cancer Center, West China School of Medicine/West China Hospital, Sichuan University"
            },
            {
                "name": "Jidan Zhou",
                "org": "Department of Radiation Oncology, Cancer Center, West China School of Medicine/West China Hospital, Sichuan University"
            },
            {
                "name": "Xiaoqin Jiang",
                "org": "Department of Radiation Oncology, Cancer Center, West China School of Medicine/West China Hospital, Sichuan University"
            },
            {
                "name": "Nianyong Chen",
                "org": "Department of Radiation Oncology, Cancer Center, West China School of Medicine/West China Hospital, Sichuan University"
            },
            {
                "name": "Sen Bai",
                "org": "Department of Radiation Oncology, Cancer Center, West China School of Medicine/West China Hospital, Sichuan University"
            },
            {
                "name": "You Lu",
                "org": "Department of Thoracic Oncology, Cancer Center and State Key Laboratory of Biotherapy, West China School of Medicine/West China Hospital, Sichuan University"
            }
        ],
        "title": "Implementation of single-breath-hold cone beam CT guided hypofraction radiotherapy for lung cancer",
        "abstract": "Background: To analyze the feasibility of active breath control (ABC), the lung tumor reproducibility and the rationale for single-breath-hold cone beam CT (CBCT)-guided hypofraction radiotherapy.Methods: Single-breath-hold CBCT images were acquired using ABC in a cohort of 83 lung cancer patients (95 tumors) treated with hypofraction radiotherapy. For all alignments between the reference CT and CBCT images (including the pre-correction, post-correction and post-treatment CBCT images), the tumor reproducibility was evaluated via online manual alignment of the tumors, and the vertebral bone uncertainties were evaluated via offline manual alignment of the vertebral bones. The difference between the tumor reproducibility and the vertebral bone uncertainty represents the change in the tumor position relative to the vertebral bone. The relative tumor positions along the coronal, sagittal and transverse axes were measured based on the reference CT image. The correlations between the vertebral bone uncertainty, the relative tumor position, the total treatment time and the tumor reproducibility were evaluated using the Pearson correlations.Results: Pre-correction, the systematic/random errors of tumor reproducibility were 4.5/2.6 (medial-lateral, ML), 5.1/4.8 (cranial-caudal, CC) and 4.0/3.6 mm (anterior-posterior, AP). These errors were significantly decreased to within 3 mm, both post-correction and post-treatment. The corresponding PTV margins were 4.7 (ML), 7.4 (CC) and 5.4 (AP) mm. The changes in the tumor position relative to the vertebral bone displayed systematic/random errors of 2.2/2.0 (ML), 4.1/4.4 (CC) and 3.1/3.3 (AP) mm. The uncertainty of the vertebral bone significantly correlated to the reproducibility of the tumor position (P < 0.05), except in the CC direction post-treatment. However, no significant correlation was detected between the relative tumor position, the total treatment time and the tumor reproducibility (P > 0.05).Conclusions: Using ABC for single-breath-hold CBCT guidance is an effective method to reduce the PTV margin of hypofraction radiotherapy for lung cancer. Using ABC, the tumor position was significantly altered relative to the vertebral position. The reproducibility of the tumor position was affected by the vertebral bone but not by the relative tumor position or the total treatment time. \u00a9 2014 Zhong et al.; licensee BioMed Central Ltd.",
        "keywords": [
            "Active breathing control",
            "PTV margin",
            "Rationale",
            "Tumor position reproducibility"
        ],
        "venue": "Radiation Oncology",
        "year": 2014,
        "id": "nNIWSTfI"
    },
    "H1Tpop2i": {
        "authors": [
            {
                "name": "Ruifeng Zhang",
                "org": "Key Laboratory of Biotherapy in Zhejiang Province, Biomedical Research Center, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University"
            },
            {
                "name": "Liuhong Shi",
                "org": "Key Laboratory of Biotherapy in Zhejiang Province, Biomedical Research Center, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Gastroenterology, The First Affiliated Hospital of Zhengzhou University"
            },
            {
                "name": "Gensheng Zhang",
                "org": "Department of Critical Care medicine, The Second Affiliated Hospital of Zhejiang University"
            },
            {
                "name": "Xiaohong Wu",
                "org": "Key Laboratory of Biotherapy in Zhejiang Province, Biomedical Research Center, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University"
            },
            {
                "name": "Fangchun Shao",
                "org": "Key Laboratory of Biotherapy in Zhejiang Province, Biomedical Research Center, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University"
            },
            {
                "name": "Guofeng Ma",
                "org": "Key Laboratory of Biotherapy in Zhejiang Province, Biomedical Research Center, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University"
            },
            {
                "name": "Kejing Ying",
                "org": "Key Laboratory of Biotherapy in Zhejiang Province, Biomedical Research Center, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University"
            }
        ],
        "title": "Transgelin as a therapeutic target to prevent hypoxic pulmonary hypertension",
        "abstract": "We previously observed that transgelin was preferentially expressed in human pulmonary arterial smooth muscle cells (PAMSCs) under hypoxia and that the upregulation of transgelin was independent of hypoxia-inducible factor 1\u03b1 (HIF-1\u03b1). Reduced transgelin expression was accompanied by significantly impaired migration ability in vitro. However, the regulation mechanism of transgelin and its function in preventing hypoxic pulmonary hypertension (HPH) was unclear. In the present study, RNA interference with hypoxia-inducible factor 2\u03b1 (HIF-2\u03b1) was employed in human PASMCs. Transgelin expression was diminished in HIF-2\u03b1-siRNA-treated cells at both the mRNA and protein levels under hypoxia. However, HIF-2\u03b1 did not transactivate the transgelin promoter directly. TGF-\u03b21 concentration in human PASMCs culture medium was higher under hypoxia, and the accumulated TGF-\u03b21 under hypoxia was regulated by HIF-2\u03b1. Furthermore, luciferase and chromatin immunoprecipitation assays indicated that TGF-\u03b21/Smad3 could bind to the transgelin promoter, resulting in increased transgelin expression. In addition to nonintact cellular migration, inhibition of transgelin expression resulted in impaired proliferation in vitro under hypoxia. A lentiviral vector used to inhibit transgelin expression was constructed and intratracheally instilled in rats 3 wk prior to hypoxia treatment. Our final results indicated that inhibition of transgelin expression locally could attenuate increased right ventricular systolic pressure and its associated cardiac and pulmonary vessel remodeling under hypoxia. Our findings indicate that HIF-2\u03b1 upregulates transgelin indirectly and that accumulated TGF-\u03b21 is a mediator in the upregulation of transgelin by HIF-2\u03b1 under hypoxia. Inhibition of transgelin expression locally could prevent HPH and pulmonary vascular remodeling in vivo. \u00a9 2014 the American Physiological Society.",
        "keywords": [
            "HIF-2\u03b1",
            "Hypoxic pulmonary hypertension",
            "Remodeling",
            "Transgelin"
        ],
        "venue": "American Journal of Physiology - Lung Cellular and Molecular Physiology",
        "year": 2014,
        "id": "H1Tpop2i"
    },
    "Tadx1Z8k": {
        "authors": [
            {
                "name": "Shaoxiong Wang",
                "org": ""
            },
            {
                "name": "Xi Lu",
                "org": ""
            },
            {
                "name": "Jian Yang",
                "org": ""
            },
            {
                "name": "Hongyong Wang",
                "org": ""
            },
            {
                "name": "Cai Yu Chen",
                "org": ""
            },
            {
                "name": "Yu Han",
                "org": ""
            },
            {
                "name": "Hongmei Ren",
                "org": ""
            },
            {
                "name": "Shuo Zheng",
                "org": ""
            },
            {
                "name": "Duofen He",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Laureano D. Asico",
                "org": ""
            },
            {
                "name": "Wei Eric Wang",
                "org": ""
            },
            {
                "name": "Pedro A. Jose",
                "org": ""
            },
            {
                "name": "Chunyu Zeng",
                "org": ""
            }
        ],
        "title": "Regulation of renalase expression by D",
        "abstract": "The dopaminergic and sympathetic systems interact to regulate blood pressure. Our previous studies showed regulation of \u03b1",
        "keywords": [
            "Dopamine receptor",
            "Hypertension",
            "Renal proximal tubule cells",
            "Renalase"
        ],
        "venue": "American Journal of Physiology - Renal Physiology",
        "year": 2014,
        "id": "Tadx1Z8k"
    },
    "StIuAfQL": {
        "authors": [
            {
                "name": "Heng Xiao",
                "org": "Key Lab of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Shaobing Cheng",
                "org": "Key Lab of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Rongliang Tong",
                "org": "Key Lab of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Zheng Lv",
                "org": "Department of Surgery"
            },
            {
                "name": "Chaofeng Ding",
                "org": "Department of Surgery"
            },
            {
                "name": "Chengli Du",
                "org": "Department of Surgery"
            },
            {
                "name": "Haiyang Xie",
                "org": "Key Lab of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Lab of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Jian Wu",
                "org": "Key Lab of Combined Multi-Organ Transplantation"
            },
            {
                "name": "Shusen Zheng",
                "org": "Key Lab of Combined Multi-Organ Transplantation"
            }
        ],
        "title": "BAG3 regulates epithelial-mesenchymal transition and angiogenesis in human hepatocellular carcinoma",
        "keywords": [
            "angiogenesis",
            "Bcl2-associated athanogene 3",
            "epithelial mesenchymal transition",
            "human hepatocellular carcinoma"
        ],
        "venue": "Laboratory Investigation",
        "year": 2014,
        "id": "StIuAfQL"
    },
    "rlHrLtl7": {
        "authors": [
            {
                "name": "Bin Jiao",
                "org": "Department of Neurology"
            },
            {
                "name": "Beisha Tang",
                "org": "Key Laboratory of Hunan Province in Neurodegenerative Disorders"
            },
            {
                "name": "Xiaoyan Liu",
                "org": "Department of Neurology"
            },
            {
                "name": "Xinxiang Yan",
                "org": "Key Laboratory of Hunan Province in Neurodegenerative Disorders"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Hunan Province in Neurodegenerative Disorders"
            },
            {
                "name": "Yi Yang",
                "org": "Key Laboratory of Hunan Province in Neurodegenerative Disorders"
            },
            {
                "name": "Junling Wang",
                "org": "Key Laboratory of Hunan Province in Neurodegenerative Disorders"
            },
            {
                "name": "Kun Xia",
                "org": "Key Laboratory of Hunan Province in Neurodegenerative Disorders"
            },
            {
                "name": "Lu Shen",
                "org": "Key Laboratory of Hunan Province in Neurodegenerative Disorders"
            }
        ],
        "title": "Identification of C9orf72 repeat expansions in patients with amyotrophic lateral sclerosis and frontotemporal dementia in mainland China",
        "abstract": "The GGGGCC repeat expansion in the C9orf72 gene was recently identified as a major cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) in white populations. To estimate the frequency of hexanucleotide repeats in patients with ALS and FTD from mainland China, we screened for C9orf72 in a cohort of 128 patients and 150 control subjects using the repeat-primed polymerase chain reaction method. We observed pathogenic repeat expansions in a family with ALS-FTD and in a patient with sporadic FTD. In the family with ALS-FTD, the proband and the 2 asymptomatic siblings exhibited C9orf72 repeat expansions, and the clinical feature of the proband was characterized by pure motor syndrome with no cognitive impairment. The patient with sporadic FTD presented primarily with deteriorating behavior and mental status. Genotype analysis revealed that the proband shared the previously reported 20-single nucleotide polymorphism risk haplotype, whereas the patient with sporadic FTD carried all single nucleotide polymorphisms except rs2814707-A. To our knowledge, this study is the first to report 2 C9orf72 mutation patients in mainland China, and they shared the similar risk haplotype identified in white populations, suggesting that ALS and FTD associated with C9orf72 mutation was probably derived from a single founder. \u00a9 2014 Elsevier Inc.",
        "keywords": [
            "Amyotrophic lateral sclerosis",
            "C9orf72",
            "Frontotemporal dementia",
            "Hexanucleotide repeats",
            "Risk haplotype"
        ],
        "venue": "Neurobiology of Aging",
        "year": 2014,
        "id": "rlHrLtl7"
    },
    "CnIlzoLn": {
        "authors": [
            {
                "name": "Yu Mao",
                "org": "Division of Cardiology, Shanghai Tongji Hospital"
            },
            {
                "name": "Xiaolong Qi",
                "org": "Institute of Digestive Disease, Shanghai Tongji Hospital"
            },
            {
                "name": "Wenjun Xu",
                "org": "Division of Cardiology, Shanghai Tongji Hospital"
            },
            {
                "name": "Haoming Song",
                "org": "Division of Cardiology, Shanghai Tongji Hospital"
            },
            {
                "name": "Mingxin Xu",
                "org": "Institute of Digestive Disease, Shanghai Tongji Hospital"
            },
            {
                "name": "Wanrong Ma",
                "org": "Institute of Digestive Disease, Shanghai Tongji Hospital"
            },
            {
                "name": "Lin Zhou",
                "org": "Division of Cardiology, Shanghai Tongji Hospital"
            }
        ],
        "title": "Serum Gamma-glutamyl transferase: A novel biomarker for coronary artery disease",
        "abstract": "Background: Atherosclerosis is a chronic inflammatory process, in which oxidative stress is the key event. Gamma-glutamyl transferase (GGT) is a cellular production of oxidants. We aimed to elucidate the relationship of serum GGT levels and coronary artery disease (CAD) in a Chinese population. Material/Methods: A total of 513 adult subjects who had undergone coronary angiography were enrolled in the study. Clinical characteristics, coronary angiography, and serum samples were collected from all the patients and analyzed for the serum GGT, blood lipids, and cardiovascular risk factors. Results: Subjects with CAD had significantly increased activity of serum GGT (p=0.003). Serum GGT levels exhibited positive correlations with alcohol intake (\u03b2=0.177, p<0.001), coronary complexity (\u03b2=0.068, p<0.001), and triacylglycerol (\u03b2=0.058, p<0.001). High-density lipoprotein cholesterol levels (\u03b2=0.157, p=0.008) and age (\u03b2=0.004, p=0.002) were negatively correlated with serum GGT in the CAD group. The coronary complexity presented a negative correlation with Ig-apolipoprotein AI (\u03b2=-2.517, p=0.001) and positive correlations with smoking (\u03b2=0.640, p<0.001), Ig-GGT (\u03b2=0.613, p=0.004), Ig high sensitivity-C reactive protein (\u03b2=0.320, p<0.001), and hypertension (\u03b2=0.286, p<0.026). Conclusions: The study showed a positive correlation between serum GGT and CAD in a Chinese population. Serum GGT levels may be a potential biomarker for CAD. \u00a9 Med Sci Monit, 2014.",
        "keywords": [
            "Cardiovascular diagnostic technique",
            "Coronary artery disease",
            "Gamma-glutamyl transpeptidase"
        ],
        "venue": "Medical Science Monitor",
        "year": 2014,
        "id": "CnIlzoLn"
    },
    "M5a9CMdU": {
        "authors": [
            {
                "name": "Xiaobo Yu",
                "org": "Key Lab. of Combined Multi-Organ Transplantation, School of Medicine, Zhejiang University"
            },
            {
                "name": "Bajin Wei",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, School of Medicine, Zhejiang University"
            },
            {
                "name": "Yifan Dai",
                "org": "Key Lab. of Combined Multi-Organ Transplantation, School of Medicine, Zhejiang University"
            },
            {
                "name": "Min Zhang",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, School of Medicine, Zhejiang University"
            },
            {
                "name": "Jian Wu",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, School of Medicine, Zhejiang University"
            },
            {
                "name": "Xiao Xu",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, School of Medicine, Zhejiang University"
            },
            {
                "name": "Guoping Jiang",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, School of Medicine, Zhejiang University"
            },
            {
                "name": "Shusen Zheng",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, School of Medicine, Zhejiang University"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Lab. of Combined Multi-Organ Transplantation, School of Medicine, Zhejiang University"
            }
        ],
        "title": "Genetic polymorphism of Interferon Regulatory Factor 5 (IRF5) correlates with allograft acute rejection of liver transplantation",
        "keywords": [
            ""
        ],
        "venue": "PLoS ONE",
        "year": 2014,
        "id": "M5a9CMdU"
    },
    "3Sb1brF8": {
        "authors": [
            {
                "name": "Shengyong Yin",
                "org": "Key Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health, Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University"
            },
            {
                "name": "Xinhua Chen",
                "org": "Key Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health, Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University"
            },
            {
                "name": "Chen Hu",
                "org": "Key Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health, Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University"
            },
            {
                "name": "Xueming Zhang",
                "org": "Key Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health, Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University"
            },
            {
                "name": "Zhenhua Hu",
                "org": "Key Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health, Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University"
            },
            {
                "name": "Jun Yu",
                "org": "Key Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health, Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University"
            },
            {
                "name": "Xiaowen Feng",
                "org": "Key Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health, Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University"
            },
            {
                "name": "Kai Jiang",
                "org": "College of Biomedical Engineering and Instrument Science, Zhejiang University"
            },
            {
                "name": "Shuming Ye",
                "org": "College of Biomedical Engineering and Instrument Science, Zhejiang University"
            },
            {
                "name": "Kezhen Shen",
                "org": "Key Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health, Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University"
            },
            {
                "name": "Haiyang Xie",
                "org": "Key Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health, Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health, Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University"
            },
            {
                "name": "Robert James Swanson",
                "org": "Anatomical Sciences Department, College of Osteopathic Medicine, Liberty University"
            },
            {
                "name": "Shusen Zheng",
                "org": "Key Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health, Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University"
            }
        ],
        "title": "Nanosecond pulsed electric field (nsPEF) treatment for hepatocellular carcinoma: A novel locoregional ablation decreasing lung metastasis",
        "abstract": "Hepatocellular carcinoma (HCC) is a highly aggressive malignancy. Nanosecond pulsed electric field (nsPEF) is a new technology destroying tumor cells with a non-thermal high voltage electric field using ultra-short pulses. The study's aim was to evaluate the ablation efficacy of nsPEFs with human HCC cell lines and a highly metastatic potential HCC xenograft model on BALB/c nude mice. The in vivo study showed nsPEFs induced HCC cell death in a dose dependent manner. On the high metastatic hepatocellular carcinoma cell line (HCCLM3) xenograft mice model, tumor growth was inhibited significantly in nsPEF-treated- groups (single dose and multi-fractionated dose). Besides a local effect, the nsPEF treatment reduced pulmonary metastases. The nsPEFs also enhanced HCC cell phagocytosis by human macrophage cell (THP1) in vitro. The nsPEF is efficient in controlling HCC progression and reducing its metastasis. NsPEF treatment may elicit a host immune response against tumor cells. This study suggests nsPEF therapy could be used as a potential locoregional therapy for hepatocellular carcinoma. \u00a9 2014 The Authors.",
        "keywords": [
            "Ablation",
            "Hepatocellular carcinoma",
            "Nanosecond pulsed electric field"
        ],
        "venue": "Cancer Letters",
        "year": 2014,
        "id": "3Sb1brF8"
    },
    "htn0DYO5": {
        "authors": [
            {
                "name": "Donghai Jiang",
                "org": "Program of Innovative Cancer Therapeutics, Key Laboratory of Combined Multi-Organ Transplantation, Ministry of Public Health, First Affiliated Hospital of Zhejiang University School of Medicine"
            },
            {
                "name": "Yuan Huang",
                "org": "Department of Chemotherapy, Zhejiang Cancer Hospital"
            },
            {
                "name": "Ning Han",
                "org": "Program of Innovative Cancer Therapeutics, Key Laboratory of Combined Multi-Organ Transplantation, Ministry of Public Health, First Affiliated Hospital of Zhejiang University School of Medicine"
            },
            {
                "name": "Mingjie Xu",
                "org": "Program of Innovative Cancer Therapeutics, Key Laboratory of Combined Multi-Organ Transplantation, Ministry of Public Health, First Affiliated Hospital of Zhejiang University School of Medicine"
            },
            {
                "name": "Liang Xu",
                "org": "Program of Innovative Cancer Therapeutics, Key Laboratory of Combined Multi-Organ Transplantation, Ministry of Public Health, First Affiliated Hospital of Zhejiang University School of Medicine"
            },
            {
                "name": "Lin Zhou",
                "org": "Program of Innovative Cancer Therapeutics, Key Laboratory of Combined Multi-Organ Transplantation, Ministry of Public Health, First Affiliated Hospital of Zhejiang University School of Medicine"
            },
            {
                "name": "Shu Wang",
                "org": "Department of Biological Sciences, National University of Singapore"
            },
            {
                "name": "Weimin Fan",
                "org": "Department of Pathology and Laboratory Medicine, Medical University of South Carolina"
            }
        ],
        "title": "Fulvestrant, a selective estrogen receptor down-regulator, sensitizes estrogen receptor negative breast tumors to chemotherapy",
        "abstract": "Drug resistance frequently results in poor prognosis and high 5-year recurrence rate in estrogen receptor-negative (ER-) breast cancer patients. Herein, we examined the reversal effects of fulvestrant on multidrug resistance (MDR) in ER- breast cancer cells. Co-administration of fulvestrant significantly sensitized ER- MDR tumors to paclitaxel both in vitro and in vivo. Further analyses indicated that fulvestrant did not affect P-gp expression, but could inhibit P-gp function and subsequently reverse P-gp mediated drug resistance in ER- breast cancer cells. These results showed that combination of fulvestrant and chemotherapeutic agents might provide an effective treatment for ER- MDR breast cancers. \u00a9 2014 Elsevier Ireland Ltd.",
        "keywords": [
            "Breast cancer",
            "Drug resistance",
            "Estrogen receptor",
            "Fulvestrant",
            "Paclitaxel"
        ],
        "venue": "Cancer Letters",
        "year": 2014,
        "id": "htn0DYO5"
    },
    "QtQXuwu6": {
        "authors": [
            {
                "name": "Chengli Du",
                "org": "Department of Hepatobiliary Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine"
            },
            {
                "name": "Zhen Lv",
                "org": "Department of Hepatobiliary Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine"
            },
            {
                "name": "Linping Cao",
                "org": "Department of Hepatobiliary Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine"
            },
            {
                "name": "Chaofeng Ding",
                "org": "Department of Hepatobiliary Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine"
            },
            {
                "name": "Owusu-ansah K. Gyabaah",
                "org": "Department of Hepatobiliary Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine"
            },
            {
                "name": "Haiyang Xie",
                "org": "Department of Hepatobiliary Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Hepatobiliary Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine"
            },
            {
                "name": "Jian Wu",
                "org": "Department of Hepatobiliary Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine"
            },
            {
                "name": "Shusen Zheng",
                "org": "Department of Hepatobiliary Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine"
            }
        ],
        "title": "MiR-126-3p suppresses tumor metastasis and angiogenesis of hepatocellular carcinoma by targeting LRP6 and PIK3R2",
        "keywords": [
            "Angiogenesis",
            "Hepatocellular carcinoma (HCC)",
            "LRP6",
            "Metastasis",
            "MiR-126-3p",
            "PIK3R2"
        ],
        "venue": "Journal of Translational Medicine",
        "year": 2014,
        "id": "QtQXuwu6"
    },
    "uVOt7Qq6": {
        "authors": [
            {
                "name": "Weijie Xiong",
                "org": "Chengdu Fifth People's Hospital and Chengdu Third People's Hospital"
            },
            {
                "name": "Qingfeng Xu",
                "org": "Radiation Physics Center, Cancer Center, West China Hospital, Sichuan University"
            },
            {
                "name": "Yong Xu",
                "org": "Department of Thoracic Oncology and State Key Laboratory of Biotherapy, Cancer Center, West China Hospital, Sichuan University"
            },
            {
                "name": "Changjin Sun",
                "org": "Chengdu Fifth People's Hospital and Chengdu Third People's Hospital"
            },
            {
                "name": "Na Li",
                "org": "Department of Oncology, Second Affiliated Hospital of Anhui Medical University"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Thoracic Oncology and State Key Laboratory of Biotherapy, Cancer Center, West China Hospital, Sichuan University"
            },
            {
                "name": "Yongmei Liu",
                "org": "Department of Thoracic Oncology and State Key Laboratory of Biotherapy, Cancer Center, West China Hospital, Sichuan University"
            },
            {
                "name": "Xiaojuan Zhou",
                "org": "Department of Thoracic Oncology and State Key Laboratory of Biotherapy, Cancer Center, West China Hospital, Sichuan University"
            },
            {
                "name": "Yongsheng Wang",
                "org": "Department of Thoracic Oncology and State Key Laboratory of Biotherapy, Cancer Center, West China Hospital, Sichuan University"
            },
            {
                "name": "Jin Wang",
                "org": "Department of Thoracic Oncology and State Key Laboratory of Biotherapy, Cancer Center, West China Hospital, Sichuan University"
            },
            {
                "name": "Sen Bai",
                "org": "Radiation Physics Center, Cancer Center, West China Hospital, Sichuan University"
            },
            {
                "name": "You Lu",
                "org": "Department of Thoracic Oncology and State Key Laboratory of Biotherapy, Cancer Center, West China Hospital, Sichuan University"
            },
            {
                "name": "Youling Gong",
                "org": "Department of Thoracic Oncology and State Key Laboratory of Biotherapy, Cancer Center, West China Hospital, Sichuan University"
            }
        ],
        "title": "Stereotactic body radiation therapy for post-pulmonary lobectomy isolated lung metastasis of thoracic tumor: Survival and side effects",
        "abstract": "Background: Stereotactic body radiation therapy (SBRT) has emerged as an alternative treatment for patients with early stage non-small cell lung cancer (NSCLC) or metastatic pulmonary tumors. However, for isolated lung metastasis (ILM) of thoracic malignances after pulmonary lobectomy, reported outcomes of SBRT have been limited. This study evaluates the role of SBRT in the treatment of such patients.Methods: A retrospective search of the SBRT database was conducted in three hospitals. The parameters analyzed in the treated patients were local control, progression-free survival (PFS), overall survival (OS), and the treatment-related side-effects.Results: In total, 23 patients with single ILM after pulmonary lobectomy treated with SBRT were identified and the median follow-up time was 14 months (range: 6.0-47.0 months). Local recurrences were observed in two patients during follow-up and the 1-year local control rate was 91.3%. Median PFS and OS for the studied cohort were 10.0 months [95% confidence interval (CI) 5.1-14.9 months] and 21.0 months (95% CI 11.4-30.6 months), respectively. Acute radiation pneumonitis (RP) of grade 2 or worse was observed in five (21.7%) and three (13.0%) patients, respectively. Other treatment-related toxicities included chest wall pain in one patient (4.3%) and acute esophagitis in two patients (8.7%). By Pearson correlation analysis, the planning target volume (PTV) volume and the volume of the ipsilateral lung exposed to a minimum dose of 5 Gy (IpV",
        "keywords": [
            "Clinical outcomes",
            "Post-lobectomy isolated lung metastasis",
            "Stereotactic body radiation therapy",
            "Thoracic tumor"
        ],
        "venue": "BMC Cancer",
        "year": 2014,
        "id": "uVOt7Qq6"
    },
    "SsMIGeNF": {
        "authors": [
            {
                "name": "Zhengtao Liu",
                "org": "Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases"
            },
            {
                "name": "Huaijun Ning",
                "org": "Department of Pediatrics, Women and Children's Hospital of Guangxi"
            },
            {
                "name": "Xiaoyin He",
                "org": "Department of Pediatrics, Women and Children's Hospital of Guangxi"
            },
            {
                "name": "Shuping Que",
                "org": "Department of Pediatrics, Women and Children's Hospital of Guangxi"
            },
            {
                "name": "Lin Zhou",
                "org": "Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases"
            }
        ],
        "title": "Meta-analysis reveals a specific association of the PNPLA3 I148M polymorphism with ALT level in adolescents",
        "abstract": "Aim: To evaluate potential link between the PNPLA3 rs738409 polymorphism and alanine aminotransferase (ALT) levels through an evidence-based study. Materials & Methods: Electronic literature databases, including PubMed, Embase and the Institute for Scientific Information, were searched for relevant studies. Pooling standardized mean differences for quantitative variables and summary odds ratios (OR) were respectively calculated using per-allele comparison. Results: Although a genotype-phenotype association was inconsistent in adults, this genetic effect was stable in adolescents. There was an approximate increase of 23% in ALT value, and 1.99-fold higher ALT elevation per risk allele increase with low heterogeneity. Conclusion: The PNPLA3 rs738409 polymorphism can have a differentiated influence on ALT level. Our meta-analysis provides reference data for the adjustment of diverse susceptibility due to the rs738409 polymorphism when evaluating liver injury in various populations.",
        "keywords": [
            "alanine aminotransferase",
            "meta-analysis",
            "patatin-like phospholipase domain containing 3",
            "systematic review"
        ],
        "venue": "Personalized Medicine",
        "year": 2015,
        "id": "SsMIGeNF"
    },
    "KhJn8yNr": {
        "authors": [
            {
                "name": "Songming Ding",
                "org": "Key Laboratory of Organ Trans-Plantation, Zhejiang Province"
            },
            {
                "name": "Guoliang Chen",
                "org": "Key Laboratory of Organ Trans-Plantation, Zhejiang Province"
            },
            {
                "name": "Wu Zhang",
                "org": "Key Laboratory of Organ Trans-Plantation, Zhejiang Province"
            },
            {
                "name": "Chunyang Xing",
                "org": "Key Laboratory of Organ Trans-Plantation, Zhejiang Province"
            },
            {
                "name": "Xiao Xu",
                "org": "Key Laboratory of Organ Trans-Plantation, Zhejiang Province"
            },
            {
                "name": "Haiyang Xie",
                "org": "Key Laboratory of Organ Trans-Plantation, Zhejiang Province"
            },
            {
                "name": "Aili Lu",
                "org": "Division of Oncology Department, First Affiliated Hospital, Zhejiang University School of Medicine"
            },
            {
                "name": "Kangjie Chen",
                "org": "Key Laboratory of Organ Trans-Plantation, Zhejiang Province"
            },
            {
                "name": "Haijun Guo",
                "org": "Key Laboratory of Organ Trans-Plantation, Zhejiang Province"
            },
            {
                "name": "Zhigang Ren",
                "org": "Key Laboratory of Organ Trans-Plantation, Zhejiang Province"
            },
            {
                "name": "Shusen Zheng",
                "org": "Key Laboratory of Organ Trans-Plantation, Zhejiang Province"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Organ Trans-Plantation, Zhejiang Province"
            }
        ],
        "title": "MRC-5 fibroblast-conditioned medium influences multiple pathways regulating invasion, migration, proliferation, and apoptosis in hepatocellular carcinoma",
        "abstract": "Background: Carcinoma associated fibroblasts (CAFs), an important component of tumor microenvironment, are capable of enhancing tumor cells invasion and migration through initiation of epithelial-mesenchymal transition (EMT). MRC-5 fibroblasts are one of the CAFs expressing alpha-smooth muscle actin. It is ascertained that medium conditioned by MRC-5 fibroblasts stimulate motility and invasion of breast cancer cells. However, its role in hepatocellular carcinoma (HCC) is less clear. The aim of our study was to investigate the effect of MRC-5-CM on HCC and explore the underlying mechanisms. Methods and results: Using a combination of techniques, the role of MRC-5-CM in HCC was evaluated. We determined that MRC-5-CM induced the non-classical EMT in Bel-7402 and MHCC-LM3 cell lines. Initiation of the non-classical EMT was mainly via quintessential redistribution of a\u03b1-, \u03b2- and \u03b3-catenin, P120 catenin, E-cadherin, and N-cadherin, rather than up-regulation of typical EMT-related transcription factors (i.e., Snail, Twist1, ZEB-1 and ZEB2). We also found that MRC-5-CM potentiated both the migration and invasion of Bel-7402 and MHCC-LM3 cells in mesenchymal movement mode through activation of the a\u03b16, \u03b23, \u03b24, \u03b27 integrin/FAK pathway and upregulation of MMP2. The flow cytometric analysis showed that MRC-5-CM induced G1 phase arrest in Bel-7402 cells with a concomitant reduction of S phase cells. In contrast, MRC-5-CM induced S phase arrest in MHCC-LM3 cells with a concomitant reduction of cells in the G2/M phase. MRC-5-CM also inhibited apoptosis in Bel-7402 cells while inducing apoptosis in MHCC-LM3 cells. Conclusion: Collectively, MRC-5-CM promoted HCC cell motility and invasiveness through initiation of the non-classical EMT, including redistribution of a\u03b1-, \u03b2- and \u03b3-catenin, P120 catenin, E-cadherin, and N-cadherin, activation of the integrin/FAK pathway, and upregulation of MMP2. Hence, MRC-5-CM exerted distinct roles in Bel-7402 and MHCC-LM3 cell viability by regulating cyclins, cyclin dependent kinases (CDKs), CDK inhibitors (CKIs), Bcl-2 family proteins and other unknown mechanosensors.",
        "keywords": [
            "EMT-related transcription factors",
            "Integrin/FAK pathway",
            "MRC-5-conditioned medium",
            "Non-classical epithelial-mesenchymal transition"
        ],
        "venue": "Journal of Translational Medicine",
        "year": 2015,
        "id": "KhJn8yNr"
    },
    "xP5LmSKM": {
        "authors": [
            {
                "name": "Shu-Qing Li",
                "org": "Wireless Communications Research Center"
            },
            {
                "name": "Chi Hou Chan",
                "org": "Wireless Communications Research Center"
            },
            {
                "name": "Leung Tsang",
                "org": "Department of Electrical Engineering"
            },
            {
                "name": "Qin Li",
                "org": "Department of Electrical Engineering"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Electrical Engineering"
            }
        ],
        "title": "Parallel implementation of the sparse-matrix/canonical grid method for the analysis of two-dimensional random rough surfaces (three-dimensional scattering problem) on a Beowulf system",
        "abstract": "Wave scattering from two-dimensional (2-D) random rough surfaces [three-dimensional (3-D) scattering problem] has been previously analyzed using the sparse-matrix/canonical grid (SM/CG) method. The computational complexity and memory requirement of the SM/CG method are O(N log N) per iteration and O(N), respectively, where N is the number of surface unknowns. Furthermore, the SM/CG method is FFT based, which facilitates the implementation on parallel processors. In this paper, we present a cost-effective solution by implementing the SM/CG method on a Beowulf system consisting of PC's (processors) connected by a 100 Base TX Ethernet switch. The workloads of computing the sparse-matrix-vector multiplication corresponding to the near interactions and the fast Fourier transform (FFT) operations corresponding to the far interactions in the SM/CG method can be easily distributed among all the processors. Both perfectly conducting and lossy dielectric surfaces of Gaussian spectrum and ocean spectrum are analyzed thereafter. When possible, speedup factors against a single processor are given. It is shown that the SM/CG method for a single realization of rough surface scattering can be efficiently adapted for parallel implementation. The largest number of surface unknowns solved in this paper is over 1.5 million. On the other hand, a problem of 131 072 surface unknowns for a PEC random rough surface of 1024 square wavelengths only requires a CPU time of less than 20 min. We demonstrate that analysis of a large-scale 2-D random rough surface feasible for a single realization and for one incident angle is possible using the low-cost Beowulf system.",
        "keywords": [
            ""
        ],
        "venue": "IEEE Transactions on Geoscience and Remote Sensing",
        "year": 2000,
        "id": "xP5LmSKM"
    },
    "mxlhf1UJ": {
        "authors": [
            {
                "name": "Shu-Qing Li",
                "org": "Department of Electronic Engineering"
            },
            {
                "name": "Chi Hou Chan",
                "org": "Department of Electronic Engineering"
            },
            {
                "name": "Leung Tsang",
                "org": "Department of Electrical Engineering"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Electrical Engineering"
            }
        ],
        "title": "Microwave emission of rough ocean surfaces with full spatial spectrum based on the multilevel expansion method",
        "abstract": "Microwave emission of ocean surfaces with full spatial spectrum is studied in this paper. For ocean surfaces with full spectrum, the rms height of roughness can be many wavelengths, and the surface size must be chosen to be larger than the longest scale wave in the spectrum. Due to computer resources, it is not straightforward to conduct numerical simulations of emission from rough surfaces with large rms height and size since a large number of unknowns will be involved. In this paper, the multilevel expansion of the sparse matrix canonical grid (SMCG) method, which is available for surfaces with large rms heights, is used to study the emission of one-dimensional (1-D) ocean surfaces. The computational complexity and the memory requirement are still in the order of O(N log(N)) and O(N), respectively, as in the SMCG method. Ocean surfaces with size 1024 wavelengths (21.9 m at 14 GHz) and spatial spectrum bandwidth between 0.858 rads/m (corresponding to the longest scale of 341.3 wavelengths) and 4691.5 rads/m (corresponding to the shortest scale of 1/16 wavelengths), which is rather wide to be regarded as a full spectrum, are studied. The maximum of the electromagnetic wavenumber-surface rms height product is up to 25.18. The surface is modeled as a lossy dielectric surface with large relative permittivity rather than as a perfectly conducting surface, which is often adopted as an approximation in the active remote sensing of ocean surfaces. A relatively high sampling density is used to ensure accuracy. The effects of the low and high portions of the spectrum on the emissivity are studied numerically. Monte Carlo simulation for ocean surfaces is also performed by exploiting the efficiency of the multilevel expansion method and the use of parallel computing techniques. The convergence of the results with respect to the sampling density is also illustrated.",
        "keywords": [
            "Durden-Vesecky spectrum",
            "Multilevel expansion method",
            "Ocean surfaces"
        ],
        "venue": "IEEE Transactions on Geoscience and Remote Sensing",
        "year": 2002,
        "id": "mxlhf1UJ"
    },
    "yupzwe5S": {
        "authors": [
            {
                "name": "Dong Chen",
                "org": "Department of Electronic Engineering"
            },
            {
                "name": "Leung Tsang",
                "org": "Department of Electrical Engineering"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Electrical Engineering"
            },
            {
                "name": "Steven C. Reising",
                "org": "Microwave Remote Sensing Laboratory"
            },
            {
                "name": "William E. Asher",
                "org": "Department of Electrical Engineering"
            },
            {
                "name": "Louis Allen Rose",
                "org": "Remote Sensing Division"
            },
            {
                "name": "Kung-Hau Ding",
                "org": "Air Force Research Laboratory"
            },
            {
                "name": "Chi-Te Chen",
                "org": "Intel Corporation"
            }
        ],
        "title": "Microwave emission and scattering of foam based on Monte Carlo simulations of dense media",
        "abstract": "The foam-covered ocean surface is treated as densely packed air bubbles coated with thin layers of seawater. We apply Monte Carlo simulations of solutions of Maxwell's equations to calculate the absorption, scattering, and extinction coefficients at 10.8 and 36.5 GHz. These quantities are then used in dense-media radiative transfer theory to calculate the microwave emissivity. Numerical results of the model are illustrated as a function of foam parameters. Results of emissivities for both horizontal polarization and vertical polarizations at 10.8 and 36.5 GHz are compared with recent experimental measurements.",
        "keywords": [
            "Dense-media radiative transfer",
            "Electromagnetic wave scattering",
            "Microwave emissivity",
            "Monte Carlo simulations",
            "Ocean foam"
        ],
        "venue": "IEEE Transactions on Geoscience and Remote Sensing",
        "year": 2003,
        "id": "yupzwe5S"
    },
    "zE3yaFba": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Department of Electrical Engineering"
            },
            {
                "name": "Leung Tsang",
                "org": "Department of Electronic Engineering"
            },
            {
                "name": "Dong Chen",
                "org": "Department of Electronic Engineering"
            }
        ],
        "title": "Polarimetric passive microwave remote sensing of wind vectors with foam-covered rough ocean surfaces",
        "abstract": "In this paper, polarimetric microwave emissions from wind-generated foam-covered ocean surfaces are investigated. The foam is treated as densely packed air bubbles coated with thin seawater coating. The absorption, scattering and extinction coefficients are calculated by Monte Carlo simulations of solutions of Maxwell equations of a collection of coated particles. The effects of boundary roughness of ocean surface are included by using the second-order small perturbation method (SPM) describing the reflection coefficients between foam and ocean. An empirical wavenumber spectrum is used to represent the small-scale wind-generated sea surfaces. The iterative method is employed to solve dense media radiative transfer (DMRT) equations, and is applied to calculate results of all four Stokes parameters of rough ocean surfaces. The theoretical results of four Stokes brightness temperatures with typical parameters of foam in passive remote sensing at 10.8 GHz, 19 GHz and 36.5 GHz are illustrated. The azimuth variations of polarimetric brightness temperature are calculated. Emission with various wind speed and foam layer thickness is studied. The results are also compared with those based on QuasiCrystalline Approximation (QCA).",
        "keywords": [
            "Dense media radiative transfer",
            "Four strokes parameters",
            "Ocean foam"
        ],
        "venue": "Radio Science",
        "year": 2003,
        "id": "zE3yaFba"
    },
    "8EBbrboX": {
        "authors": [
            {
                "name": "Qin Li",
                "org": "University of Washington"
            },
            {
                "name": "L. Tsang",
                "org": "City University of Hong Kong"
            },
            {
                "name": "Lin Zhou",
                "org": "University of Washington"
            }
        ],
        "title": "Study of Microwave Signatures of Soils with Various Rough Surface Spectra Based on 3-D Numerical Simulations of Maxwell Equations",
        "abstract": "The backscattering coefficients of wet soil surface are studied with the 3-dimensional numerical simulations of Maxwell equations. To improve the accuracy of the simulations, we have recently used the RWG basis functions. Using the simulation results, we study the angular, frequency, and polarimetric dependence of the scattering from different rough surface spectra. The simulation results are compared with the experimental measurements from real-life soil surface for backscattering coefficients at L and C frequency bands and at the multi-incidence angles. The fairly good agreements are observed for the fixed physical surface roughness parameters at two frequency bands.",
        "keywords": [
            ""
        ],
        "venue": "International Geoscience and Remote Sensing Symposium (IGARSS)",
        "year": 2003,
        "id": "8EBbrboX"
    },
    "8lKvl55i": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Department of Electrical Engineering"
            },
            {
                "name": "Leung Tsang",
                "org": "Department of Electronic Engineering"
            },
            {
                "name": "Vikrarn Jandhyala",
                "org": "Department of Electrical Engineering"
            },
            {
                "name": "Qin Li",
                "org": "Department of Electrical Engineering"
            },
            {
                "name": "Chi H. Chan",
                "org": "Department of Electronic Engineering"
            }
        ],
        "title": "Emissivity simulations in passive microwave remote sensing with 3-D numerical solutions of maxwell equations",
        "abstract": "In the numerical Maxwell-equation model (NMM3D) of rough-surface scattering, we solve Maxwell equations in three dimensions to calculate emissivities for applications in passive microwave remote sensing of soil and ocean surfaces. The difficult cases for soil surfaces are with exponential correlation functions when the surfaces have fine-scale structures of large slopes. The difficulty for ocean surfaces is that because the emissivities are close to that of a flat surface, the emissivities have to be calculated accurately to correctly assess the rough-surface effects. In this paper, the accuracies of emissivity calculations are improved by using Rao-Wilton-Glisson basis functions. We further use sparse matrix canonical method to solve the matrix equation of Poggio-Miller-Chang-Harrington-Wu integral equations. Energy conservation checks are provided for the simulations. Comparisons are made with results from the pulse basis function. Numerical results are illustrated for soil and ocean surfaces respectively with exponential correlation function and ocean spectrum. The emissivities of soil are illustrated at both L- and C-bands and at multiple incidence angles for the same physical roughness parameters. The brightness temperatures for ocean surfaces are illustrated for cases with various wind speeds. We compare results with those from the sparse matrix methods. Comparisons are also made with experimental emissivity measurements of soil surfaces. Parallel computation is also implemented. Lookup tables of emissivities based on NMM3D are provided.",
        "keywords": [
            "Electromagnetic scattering",
            "Integral equations",
            "Microwave remote sensing",
            "Rao-Wilton-Glisson (RWG)",
            "Rough surface",
            "Sparse-matrix canonical-grid (SMCG)"
        ],
        "venue": "IEEE Transactions on Geoscience and Remote Sensing",
        "year": 2004,
        "id": "8lKvl55i"
    },
    "fp6rwFeo": {
        "authors": [
            {
                "name": "Efe A. Ok",
                "org": "Department of Economics"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Economics and Finance"
            }
        ],
        "title": "The choquet bargaining solutions",
        "abstract": "We axiomatically investigate the problem of rationalizing bargaining solutions by social welfare functions that are linear in every rank-ordered subset of R",
        "keywords": [
            "Axiomatic bargaining theory",
            "Choquet integral generalized Ginis"
        ],
        "venue": "Games and Economic Behavior",
        "year": 2000,
        "id": "fp6rwFeo"
    },
    "RGgY3APu": {
        "authors": [
            {
                "name": "Indrajit Ray",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            }
        ],
        "title": "Game theory via revealed preferences",
        "abstract": "We investigate equilibrium notions in game theory from the revealed preference approach. For extensive game forms with complete information, we derive a set of independent necessary and sufficient conditions for the observed outcomes to be rationalized by subgame-perfect Nash equilibrium. Journal of Economic Literature Classification Numbers: C72, C92. \u00a9 2001 Academic Press.",
        "keywords": [
            ""
        ],
        "venue": "Games and Economic Behavior",
        "year": 2001,
        "id": "RGgY3APu"
    },
    "LMruIiLr": {
        "authors": [
            {
                "name": "Stephen Ching",
                "org": "Department of Economics and Finance"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Economics"
            }
        ],
        "title": "Multi-valued strategy-proof social choice rules",
        "abstract": "In this paper we introduce a new definition of strategy-proofness for multi-valued social choice correspondences. We prove two Gibbard-Satterthwaite type results for strategy-proof social choice correspondences. These results show that allowing multiple outcomes as social choices will not necessarily lead to an escape from the Gibbard-Satterthwaite impossibility theorem.",
        "keywords": [
            ""
        ],
        "venue": "Social Choice and Welfare",
        "year": 2002,
        "id": "LMruIiLr"
    },
    "P1SUuIIK": {
        "authors": [
            {
                "name": "Guang-Zhen Sun",
                "org": "Faculty of Social Sciences/Humities"
            },
            {
                "name": "Xiaokai Yang",
                "org": "Department of Economics"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Economics"
            }
        ],
        "title": "General equilibria in large economies with endogenous structure of division of labor",
        "abstract": "We study a general equilibrium model with specialization and division of labor. The market coordinates all individual's decisions in choosing their patterns of specialization in order to utilize positive network effects of division of labor net of transaction costs. We establish the equilibrium existence theorem, the first and second welfare theorems, and the core equivalence for a family of general equilibrium models with both possible increasing returns and transaction costs. Using an analytical framework with consumer-producers, economies of specialization, and transaction costs, we resurrect the spirit of the classical economics of the division of labor in a modern body of mathematical formalism. \u00a9 2004 Elsevier Inc. All rights reserved.",
        "keywords": [
            "Consumer-producer",
            "General equilibrium",
            "Increasing return to specialization",
            "Large economies",
            "Transaction costs"
        ],
        "venue": "Journal of Economic Behavior and Organization",
        "year": 2004,
        "id": "P1SUuIIK"
    },
    "90VRaoqr": {
        "authors": [
            {
                "name": "Yongsheng Xu",
                "org": "Department of Economics"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Economics"
            }
        ],
        "title": "Rationalizability of choice functions by game trees",
        "abstract": "Collective choices are often cyclic and cannot be rationalized by maximization of a single linear ordering. In this paper, we identify conditions under which collective choices, potentially cyclic, can be rationalized by extensive games with perfect information. \u00a9 2006 Elsevier Inc. All rights reserved.",
        "keywords": [
            "Choice function",
            "Divergence consistency",
            "Game tree",
            "Rationalizability",
            "Separability"
        ],
        "venue": "Journal of Economic Theory",
        "year": 2007,
        "id": "90VRaoqr"
    },
    "EDRhDZmq": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Department of Economics"
            }
        ],
        "title": "Nash implementation in pure public good economies",
        "abstract": "I study Nash implementation in a model of pure public good economies without the controversial no veto power condition. I prove that any social choice correspondence that is monotonic and satisfies unanimity and minimal liberty can be implemented in Nash equilibrium. \u00a9 2007 Elsevier B.V. All rights reserved.",
        "keywords": [
            "Minimal liberty",
            "Nash implementation",
            "No veto"
        ],
        "venue": "Economics Letters",
        "year": 2008,
        "id": "EDRhDZmq"
    },
    "mOY3V2qA": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Shou-Chun Lou",
                "org": ""
            },
            {
                "name": "Jie Zhao",
                "org": ""
            }
        ],
        "title": "An optimization apportion model of target based on genetic algorithms",
        "abstract": "This paper analyses the characteristic of mixing allocation for the present antiaircraft defense, combines the present state of antiaircraft defense weapon in our country, and proposes the optimization apportion model of target based on Genetic Algorithms. It is efficiently to solve the complicate and difficult problem of optimization apportion for target. So the antiaircraft defense combat efficacy for surface to air missile weapon system is raised.",
        "keywords": [
            "Genetic algorithms",
            "Model",
            "Optimization apportion"
        ],
        "venue": "Xitong Fangzhen Xuebao/Acta Simulata Systematica Sinica",
        "year": 2001,
        "id": "mOY3V2qA"
    },
    "6yptytAI": {
        "authors": [
            {
                "name": "Yong-Wen Zhu",
                "org": "Airforce Missile College of Technology University"
            },
            {
                "name": "Shou-Chun Lou",
                "org": "Airforce Missile College of Technology University"
            },
            {
                "name": "Lin Zhou",
                "org": "Airforce Missile College of Technology University"
            },
            {
                "name": "Er-Qi Ding",
                "org": "Airforce Missile College of Technology University"
            }
        ],
        "title": "Proportional navigation trajectory simulation in air defence system",
        "abstract": "Some SAM was discussed. Using a series of hypothesis to design proportional navigation simulation trajectory that satisfied the counterwork simulation; Using the method of instantaneous balance to handle the some SAM aerodynamic parameter. In result, It formed the balance pitch coefficient and side coefficient after the aerodynamic parameter being handled. Under the perfect work condition of the missile control system, the body of normal force and side force equaled to the requirement force could be educed. Through this conclusion, the trajectory equation was constituted. From the simulation, It can educe that the equation of ballistic trajectory by the hypothesis is true. The equation of ballistic trajectory can describe some SAM trajectory characteristic.",
        "keywords": [
            "Aerodynamic Parameter",
            "Proportional Navigation Trajectory",
            "SAM",
            "Simulation of Trajectory"
        ],
        "venue": "Xitong Fangzhen Xuebao / Journal of System Simulation",
        "year": 2005,
        "id": "6yptytAI"
    },
    "frCnTEJo": {
        "authors": [
            {
                "name": "Yong-Wen Zhu",
                "org": "Air force Missile College"
            },
            {
                "name": "Shou-Chun Lou",
                "org": "Air force Missile College"
            },
            {
                "name": "Lin Zhou",
                "org": "Air force Missile College"
            },
            {
                "name": "Er-Qi Ding",
                "org": "Air force Missile College"
            }
        ],
        "title": "Three point trajectory simulation in air defense system",
        "abstract": "In order to evaluate campaign in the counterwork simulation system, some type of SAM trajectory needed to be modeled upon. Some hypothesis was used to resolve the launching of slope model and the revising of three point guide trajectory. From simulation results, it is found that the hypothesis is right, and the designed trajectory accords with the demanding, that is capable of analyzing the system.",
        "keywords": [
            "Aerodynamic Parameter",
            "SAM",
            "Simulation of Trajectory",
            "Three Point Trajectory"
        ],
        "venue": "Xitong Fangzhen Xuebao / Journal of System Simulation",
        "year": 2006,
        "id": "frCnTEJo"
    },
    "DVPAMy88": {
        "authors": [
            {
                "name": "Lin-Feng Gao",
                "org": "Missile Institute"
            },
            {
                "name": "Yan-Bo Du",
                "org": "Missile Institute"
            },
            {
                "name": "Lin Zhou",
                "org": "Missile Institute"
            }
        ],
        "title": "Design and realization of air-raid entity flow federate based on MAS",
        "abstract": "The feasibility of MAS (Multi-Agent System) application in HLA simulation was analyzed and the application rules were put forward. Based on the comparison of the deep-thinking Agent, the reactive Agent and the average object, the air-raid entity flow federate was involved in detailed design and realization. A solid foundation for the later development of air-raid entity flow federate was laid and a useful try and thought for design and realizing of federates in HLA simulation was provided.",
        "keywords": [
            "Federate",
            "HLA",
            "MAS",
            "Simulation"
        ],
        "venue": "Xitong Fangzhen Xuebao / Journal of System Simulation",
        "year": 2007,
        "id": "DVPAMy88"
    },
    "riBi2BAq": {
        "authors": [
            {
                "name": "Jun Wang",
                "org": "Missile Inst."
            },
            {
                "name": "Lin Zhou",
                "org": "Missile Inst."
            },
            {
                "name": "Hua-Zhen Bai",
                "org": "The People's Liberation Army of China 93655 Corps"
            }
        ],
        "title": "Arithmetic of dependability matrixes in the ADC effectiveness evaluation model",
        "abstract": "At present, the ADC model is a standard method used to evaluate the complex weapon system effectiveness and has been widely applied in practice. But in most applications, the computation of the dependability matrix is unduly simplified, so that a larger error is caused in effectiveness evaluation result. In order to improve the validity and reliability of the model, the random state of weapon systems after accomplishing the mission at random time is regarded as a random process, and the computing model of the dependability matrix is established by using Kolmogorov backward and forward equations of the continuous time homogeneous Markov chain. The transfer probability is found by solving the matix differential equation. Finally, an application case example which is based on a short range ground-to-air missile weapon system effectiveness evaluation validates the model and the future research orientation is put forward.",
        "keywords": [
            "ADC model",
            "Dependability",
            "Effectiveness evaluation"
        ],
        "venue": "Xi Tong Gong Cheng Yu Dian Zi Ji Shu/Systems Engineering and Electronics",
        "year": 2008,
        "id": "riBi2BAq"
    },
    "2q8Imezm": {
        "authors": [
            {
                "name": "Jun Wang",
                "org": "Missile Institute"
            },
            {
                "name": "Lin Zhou",
                "org": "Missile Institute"
            },
            {
                "name": "Hu-Min Lei",
                "org": "Missile Institute"
            }
        ],
        "title": "Forecast model and arithmetic on hit point of ground-to-air missile and aerial target",
        "abstract": "Owing to the fact that the hit point coordinates of missile and target is one of the key bases for the Ground-to-Air Missile command and control system to make firing decisions, it's essential to develop a rapid and accurate forecast model or arithmetic. Aiming at non-maneuvering aerodynamic target, an analytic forecast model and an iterative forecast arithmetic on the hit point were studied. In the analytic model, the guidance method of missile was regarded approximately as the parallel approaching method. The missile flied to the instantaneous hit point at the constant velocity. In the iterative arithmetic, the coordinates of the instantaneous hit point was forecast by solving the kinematic trajectory of missile according to line of sight (LOS) and proportional navigation (PN) method usually applied in Ground-to-Air missile. The simulation analysis indicates that both the analytic model and the iterative arithmetic are logical and effective. The former is brief and fast and applicable for combat unit command and control system. The latter is more precise and real-time and applicable for fire unit command and control system. Both are very valuable to engineering application and provide a practical model technique for the development of air defense command and control system.",
        "keywords": [
            "Aerial target",
            "Command and control system",
            "Forecast",
            "Ground-to-Air Missile",
            "Hit point"
        ],
        "venue": "Xitong Fangzhen Xuebao / Journal of System Simulation",
        "year": 2009,
        "id": "2q8Imezm"
    },
    "BumnaiDW": {
        "authors": [
            {
                "name": "Jun Wang",
                "org": ""
            },
            {
                "name": "Hu-Min Lei",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Dai-Jun Liu",
                "org": ""
            }
        ],
        "title": "Medium and far range ground-to-air missile weapon system combat effectiveness simulation",
        "abstract": "The combat effectiveness of far range Ground-to-Air Missile weapon system was evaluated and studied before and after the system was equipped new type of medium range Ground-to-Air Missile. After the combat simulation process was analyzed, the combat simulation system was constructed. Then target threat evaluation and interception sequencing model, target interception feasibility judgment model and fire assignment model were discussed in detail. Finally a simulation case was given, and the simulation result was also analyzed, which provided a kind of effective tool for reasoning parameter of the medium range Ground-to-Air Missile, deciding adding number and making a price of it.",
        "keywords": [
            "Combat effectiveness",
            "Fire assignment",
            "Medium and far range ground-to-air missile weapon system",
            "Simulation"
        ],
        "venue": "Xitong Fangzhen Xuebao / Journal of System Simulation",
        "year": 2010,
        "id": "BumnaiDW"
    },
    "wEkpaHmu": {
        "authors": [
            {
                "name": "Jun Wang",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Hu-Min Lei",
                "org": ""
            },
            {
                "name": "Dai-Jun Liu",
                "org": ""
            }
        ],
        "title": "Medium and far range ground-to-air missile system effectiveness evaluation model",
        "abstract": "A mathematical model of medium and far range Ground-to-Air Missile system effectiveness evaluation was established with the application of ADC method. Typical reliability logic configuration was analyzed, availability matrix of weapon system was worked out with the appropriate computation hypothesis; Dependability matrix of weapon system was solved by using Kolmogorov Backward and Forward Equations of the continuous time homogeneous Markov chain; The mathematical model of capability exponent system was established by selecting target characters, firing capability, anti-jamming capability, missile capability and mobility capability. An application example validates the model and the future research orientation is put forward.",
        "keywords": [
            "ADC model",
            "Effectiveness evaluation",
            "Medium and far range ground-to-air missile",
            "System effectiveness"
        ],
        "venue": "Xitong Fangzhen Xuebao / Journal of System Simulation",
        "year": 2010,
        "id": "wEkpaHmu"
    },
    "kUW1F2Aw": {
        "authors": [
            {
                "name": "Yu-Zhe Wang",
                "org": "Missile Institute"
            },
            {
                "name": "Ying-Jie Lei",
                "org": "Missile Institute"
            },
            {
                "name": "Lin Zhou",
                "org": "Missile Institute"
            },
            {
                "name": "Run-Ling Li",
                "org": "Air Force Agency Office of 232 Factory in Beijing"
            }
        ],
        "title": "Intuitionistic fuzzy discrete particle swarm algorithm",
        "abstract": "On the basis of the analysis and research on discrete particle swarm optimization algorithm(DPSO), an improved DPSO algorithm(IFDPSO) based on intuitionistic fuzzy entropy is proposed, which takes the intuitionistic fuzzy entropy as the measure of the state of particle swarm and the parameter of velocity mutation. With the location mutation strategy, the IFDPSO can possibly search as much as possible sub-optimal location and its neighborhood, and the algorithm ability of searching global best value is intensified. The experimental data shows that, in solving large scale integer programming problem such as 0-1 knapsack problem, IFDPSO algorithm represents more effective than DPSO algorithm and ant colony optimization(ACO) algorithm, which provides a new way for solving 0-1 knapsack problem.",
        "keywords": [
            "Discrete particle swarm optimization algorithm",
            "Intuitionistic fuzzy entropy",
            "Intuitionistic fuzzy particle"
        ],
        "venue": "Kongzhi yu Juece/Control and Decision",
        "year": 2012,
        "id": "kUW1F2Aw"
    },
    "hHGPoseN": {
        "authors": [
            {
                "name": "Haiying Ma",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Li Liu",
                "org": ""
            },
            {
                "name": "Yue Bao",
                "org": ""
            }
        ],
        "title": "RETRACTED ARTICLE: Research on equipment health state evaluation model based on deterioration degree",
        "abstract": "In order to evaluate the equipment health state and implement the equipment condition maintenance, deterioration degree conception was introduced in this paper. Taking the characteristic parameter of the equipment as the evaluation index, the model of variable weight fuzzy comprehensive evaluation based on deterioration degree was established. Finally, combined with the practical work of air defense missile, an evaluation example is analyzed to validated the effectiveness of the model. \u00a9 2013 IEEE.",
        "keywords": [
            "anti-air missile equipment",
            "deterioration degree",
            "health state evaluation",
            "variable weight fuzzy"
        ],
        "venue": "QR2MSE 2013 - Proceedings of 2013 International Conference on Quality, Reliability, Risk, Maintenance, and Safety Engineering",
        "year": 2013,
        "id": "hHGPoseN"
    },
    "i0uNFZLd": {
        "authors": [
            {
                "name": "Yu-Zhe Wang",
                "org": "Missile Institute"
            },
            {
                "name": "Lin Zhou",
                "org": "Missile Institute"
            },
            {
                "name": "Yi Wang",
                "org": "Missile Institute"
            },
            {
                "name": "Jie Zhao",
                "org": "Missile Institute"
            }
        ],
        "title": "Brittleness of air defense equipment support command system",
        "abstract": "This paper studies the main structure of the Brigade ADESCS(Air Defense Equipment Support Command System, ADESCS), and decomposes the risk events that triggering system failure. Second, on analysis of system structure and risk, the following part redefines the brittleness and the relationship between brittleness roles in ADESCS, then brings up three kinds of basic brittle processes in system. At last, with ADESCS brittleness concepts, the last part describes brittleness spreading procedure base on the relationship between risk events and sub systems, and puts forward BCS(Brittleness Chain Structure, BCS) model with its solving method and the related example.",
        "keywords": [
            "Air defense missile",
            "Brittleness",
            "Brittleness chain structure",
            "Equipment support command",
            "Relative brittleness",
            "Risk"
        ],
        "venue": "Complex Systems and Complexity Science",
        "year": 2013,
        "id": "i0uNFZLd"
    },
    "Rt6ihKKj": {
        "authors": [
            {
                "name": "Weihua Gao",
                "org": "Department of Nephrology"
            },
            {
                "name": "Xing Lu",
                "org": "Department of Nephrology"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Nephrology"
            }
        ],
        "title": "Factors affecting the concentration of citrate solution in dialyzers when using citrate hemodialysate in vitro",
        "abstract": "Objective: To observe the factors that affect the concentration of citrate solution in hollow fiber when using citrate hemodialysate. Methods: By modeling hemodialysis in vitro, we used 6 types of hemodizlyzers, different blood flow-rates, different dialysate flow - rates and different fluids instead of blood to hemodialyses in vitro to detect the citrate concentration in hollow fiber. Results: The citrate concentrations in different hemodialyzers were F60>FB130UGA>GAHP130>F6>FB-130AGA>WS-70. The concentrations at different dialysate flow-rates were 500 mL\u00b7min",
        "keywords": [
            "Anticoagulation",
            "Citrate",
            "Concentration",
            "Hemodialysate"
        ],
        "venue": "Journal of Xi'an Medical University, Chinese Edition",
        "year": 2002,
        "id": "Rt6ihKKj"
    },
    "99F53Prx": {
        "authors": [
            {
                "name": "Dengfu Zhao",
                "org": "Sch. of Elec. Eng."
            },
            {
                "name": "Lin Zhou",
                "org": "Sch. of Elec. Eng."
            },
            {
                "name": "Xuhui Shen",
                "org": "Sch. of Elec. Eng."
            },
            {
                "name": "Jiangshe Zhang",
                "org": "Sch. of Elec. Eng."
            },
            {
                "name": "Xifan Wang",
                "org": "Sch. of Elec. Eng."
            }
        ],
        "title": "Short term load forecasting using fuzzy model of the orthogonal least square method",
        "abstract": "An algorithm for short term load forecasting based on a fuzzy model of the orthogonal least square method (OLS) is presented. The generation of fuzzy rules, and the selection of the model inputs and membership functions are all obtained from historical data. Therefore, the bottle-neck difficulty in knowledge acquaintance by questionnaire and experience is overcome. In the mathematic model, identification of the premise part and consequent part is separately accomplished. In the practical examples, the accuracy of this method is higher than that of the RBF method by 0.3%-0.5%. With this method, the computing time is only one second for every model.",
        "keywords": [
            "Fuzzy inference system",
            "Load forecasting",
            "Orthogonal least square method"
        ],
        "venue": "Hsi-An Chiao Tung Ta Hsueh/Journal of Xi'an Jiaotong University",
        "year": 2002,
        "id": "99F53Prx"
    },
    "68B5CBZ8": {
        "authors": [
            {
                "name": "Baosong Gui",
                "org": ""
            },
            {
                "name": "Lin Gui",
                "org": ""
            },
            {
                "name": "Liangqi Wang",
                "org": ""
            },
            {
                "name": "Xing L\u00fc",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Ruijun Guo",
                "org": ""
            },
            {
                "name": "Ganglian Yao",
                "org": ""
            }
        ],
        "title": "A new type concentrated anticoagulant hemodialysate on the high risk renal failure patients with bleeding",
        "abstract": "Objective: To observe the anticoagulant effect of the new type of concentrated anticoagulant hemodialysate of citrate on the high risk renal failure patients with bleeding. Methods: 38 patients were divided into 2 groups according to hemodialysis manners. Group I was Saline-flush hemodialysed with bicarbonate hemodialysate, Group II was hemodialysed with cirate hemodialysate without any anticoagulant. ACT, iCa",
        "keywords": [
            "Anticoagution",
            "Citrate",
            "Hemodialysate",
            "Renal failure"
        ],
        "venue": "Journal of Xi'an Jiaotong University (Medical Sciences)",
        "year": 2003,
        "id": "68B5CBZ8"
    },
    "87VrZc0J": {
        "authors": [
            {
                "name": "Liqun Ma",
                "org": ""
            },
            {
                "name": "Rongguo Fu",
                "org": ""
            },
            {
                "name": "Liangqi Wang",
                "org": ""
            },
            {
                "name": "Xing L\u00fc",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Baosong Gui",
                "org": ""
            }
        ],
        "title": "The effect of calcium supplement rate on anticoagulation of the new citrate concentrated hemodialysate",
        "abstract": "Objective: To study the effect of calcium supplement rate on anticoagulation of the new citrate concentrated hemodialysate. Methods: Twenty-eight patients were divided into 5 groups according to calcium supplement rate. Their symptoms, venous blood pressure, calcium concentration, ACT and blood gas analysis were monitored during hemodialysis. Results: When calcium supplement rate was 45 mL\u00b7h",
        "keywords": [
            "Anticoagulation",
            "Calcium supplement rate",
            "Citrate",
            "Hemodialysate"
        ],
        "venue": "Journal of Xi'an Jiaotong University (Medical Sciences)",
        "year": 2003,
        "id": "87VrZc0J"
    },
    "u68S4Tmp": {
        "authors": [
            {
                "name": "Rongguo Fu",
                "org": ""
            },
            {
                "name": "Zhongdong Wang",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Hongli Zhang",
                "org": ""
            },
            {
                "name": "Liqun Ma",
                "org": ""
            },
            {
                "name": "Xingying Zhang",
                "org": ""
            },
            {
                "name": "Xiaoqin Ma",
                "org": ""
            }
        ],
        "title": "Effects of puerarin injection on c-Fos protein of renal tubule cells during ischemic-reperfusion in kidney",
        "abstract": "Objective: To investigate the role of puerarin on acute renal ischemia-reperfusion injury and its mechanism. Methods: Acute renal ischemia-reperfusion injury rat model was established by placing the atraumatic vascular clamp in renal pedical for 30 minutes. Rats in puerarin group were given puerarin injection 30 mg/kg before ischemia. Immunohistochemical methods were used to detect the changes of expression of c-Fos proteins; pathomorphological changes of renal ischemia-reperfusion injury were also observed, and the occurrence of apoptosis was detected by TUNEL method. Results: The pathological changes mainly occurred in the tubular epithelial cells of rat kidneys. The apoptosis index increased in the kidneys of ischemia-reperfusion group and puerarin group, and peaked at 48 h of reperfusion (P<0.01). c-Fos protein mainly expressed in renal distal convoluted tubules, but the expression of c-Fos in puerarin group was still less than that in the ischemia-reperfusion group. In control group, apoptosis of renal tubule cells and c-Fos protein expression was little. Conclusion: Chinese herb puerarin can protect kidney against ischemia after acute renal ischemia-reperfusion injury, which may be associated with decreased c-Fos protein expression in rats.",
        "keywords": [
            "c-Fos",
            "Ischemia/reperfusion injury",
            "Puerarin",
            "Renal"
        ],
        "venue": "Journal of Xi'an Jiaotong University (Medical Sciences)",
        "year": 2005,
        "id": "u68S4Tmp"
    },
    "JNOFk7Nb": {
        "authors": [
            {
                "name": "Dan Zhu",
                "org": "Department of Nephrology"
            },
            {
                "name": "Dengfeng Gao",
                "org": "Department of Cardiology"
            },
            {
                "name": "Ning Ning",
                "org": "Department of Nephrology"
            },
            {
                "name": "Baosong Gui",
                "org": "Department of Nephrology"
            },
            {
                "name": "Ganglian Yao",
                "org": "Department of Nephrology"
            },
            {
                "name": "Xiaohong Wei",
                "org": "Department of Nephrology"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Nephrology"
            },
            {
                "name": "Xuefen An",
                "org": "Department of Nephrology"
            }
        ],
        "title": "Effect of all-trans-retinoic acid on tubulointerstitial macrophage infiltration in rats with renal tubulointerstitial fibrosis",
        "abstract": "Objective: To investigate the effect of at-RA in macrophage accumulation in tubulointerstitium of rats with renal tubulointerstitial fibrosis. Methods: Unilateral ureteral obstructive (UUO) rat animal models were used for the study. 40 SD rats were randomly divided into 5 grou50: sham group, UUO group, benazepril group, low-dose at-RA groups and high-dose at-RA groups. The rats were under intragastric administration by benazepril 10 mg/(kg \u00b7 d) in benazepril group, and by at-RA 10 mg/(kg \u00b7 d) in low-dose at-RA group and 20 mg/(kg \u00b7 d) in high-dose at-RA group and by sodium chloride in tales doses in sham group and UUO group from the day before the operation to 14 day after operation. Immunohistochemistry staining of CD68 and Col III was used to define the macrophage accumulation and expression of interstitial Col III. The degree of tubulointerstitial damage was scored by HE and Masson staining. Results: Tubulointerstitial macrophage infiltration were all significantly reduced by at-RA or benazepril treatment. They also improved the histological changes of UUO rats and inhibited interstitial colIII deposition. Conclusion: Reduction of interstitial macrophage infiltration may be an important event by which at-RA or benazepril prevents renal injury caused by UUO.",
        "keywords": [
            "All-trans-retinoic acid",
            "Col III",
            "Fibrosis",
            "Interstitial",
            "Macrophage"
        ],
        "venue": "Journal of Xi'an Jiaotong University (Medical Sciences)",
        "year": 2006,
        "id": "JNOFk7Nb"
    },
    "FPxmgeon": {
        "authors": [
            {
                "name": "Li Wang",
                "org": "Division of Nephrology"
            },
            {
                "name": "Chuan-Lu Ren",
                "org": "Department of Laboratory"
            },
            {
                "name": "Li Xiao",
                "org": "Division of Nephrology"
            },
            {
                "name": "Jun-Jie Tan",
                "org": "Division of Nephrology"
            },
            {
                "name": "Hua-Fang Ni",
                "org": "Division of Nephrology"
            },
            {
                "name": "Zhuo-Wen Yin",
                "org": "Division of Nephrology"
            },
            {
                "name": "Lin Zhou",
                "org": "Division of Nephrology"
            }
        ],
        "title": "Effectiveness and safety of intravenous iron supplementaion in patients with renal anaemia on hemodialysis",
        "abstract": "Objective: To determine and compare the effectiveness and safety of intravenous iron supplementation with oral ferrous sulfate in hemodialysis patients treated with recombinant human erythropoietin (rhEPO). Methods: Ninety hemodialysis patients were divided into two groups. In intravenous group, patients were given iron dextran 100 mg intravenously during each hemodialysis session. In oral group, patients were given ferrous sulfate 525 mg one time per day for 8 weeks. Each patient of both groups received rhEPO 120-150 U/kg per week. The efficacy was assessed by the changes in Hb, ferritin and transferrin saturation values. Results: There were no differences between intravenous and oral groups in sex,, age, body weight, duration of hemodialysis, Hb values, ferritin and transferrin saturation before treatment. At the end of the trial, the Hb levels of both groups significantly increased, but the increasing rate in intravenous group was markedly higher than that in oral group (P<O. 01). There was no difference in average dosage of rhEPO between two groups. The levels of ferritin and transferrin saturation significantly increased after treatment in both groups, but the levels of ferritin and transferrin saturation in intravenous group were higher than those in oral group, respectively (P<O. 001). The serum levels of Scr, Bun, AST, AlP, Alb and CRP in both groups did not change significantly. There were no severe adverse events in both groups, and the incidence of adverse events in intravenous group was lower than that in oral group (P=0. 016). Conclusion: The intravenous iron supplementation may induce Hb level to rise faster with less adverse events and its amount needed for patients can be evaluated more accurately than oral ferrous preparation.",
        "keywords": [
            "Anemia, renal",
            "Erythropoietin, recombinant",
            "Iron",
            "Renal dialysis"
        ],
        "venue": "Pharmaceutical Care and Research",
        "year": 2006,
        "id": "FPxmgeon"
    },
    "Ol2KkeXa": {
        "authors": [
            {
                "name": "Ganglian Yao",
                "org": "Institute of Nephrology"
            },
            {
                "name": "Tingting Liao",
                "org": "Institute of Nephrology"
            },
            {
                "name": "Lin Zhou",
                "org": "Institute of Nephrology"
            },
            {
                "name": "Meiru Li",
                "org": "Institute of Nephrology"
            },
            {
                "name": "Haozhen Yuan",
                "org": "Institute of Nephrology"
            },
            {
                "name": "Baosong Gui",
                "org": "Institute of Nephrology"
            }
        ],
        "title": "Serum MMP-9 and TIMP-1 levels in patients with chronic kidney disease after oxymatrine treatment",
        "abstract": "Objective: To study the effect of oxymatrine on renal interstitial fibrosis in patients with chronic kidney disease and illuminate the mechanism. Methods: Totally 40 patients were divided into 2 groups according to glomerular filtration rate (GFR) level: CKD I group and CKD II group. Then each group was divided into 2 subgroups stratifiedly and randomly. They were conventional group and oxymatrine group. ELISA was employed to measure MMP-9 and TIMP-1 activities in the plasma samples of 40 CKD patients and 10 control subjects. Results: The level of TIMP-1 was higher in conventional group than in oxymatrine group (P<0. 05), but the level of MMP-9 was lower than that in oxymatrine group (P<0. 05). Conclusion: Oxymatrine could degrade renal interstitial fibrosis by reducing TlMP-1 and restaring MMP-9 level, maintaining MMP-9/TIMP-1 balance, and reducing ECM deposits.",
        "keywords": [
            "Chronic kidney disease",
            "Matrix metalloproteinase-9 (MMP-9)",
            "Oxymatrine",
            "Renal interstitial fibrosis",
            "Tissue inhibitor of metalloproteinases 1 (TIMP-1)"
        ],
        "venue": "Journal of Xi'an Jiaotong University (Medical Sciences)",
        "year": 2008,
        "id": "Ol2KkeXa"
    },
    "YCdsx9Wv": {
        "authors": [
            {
                "name": "Tingting Liao",
                "org": "Department of Nephrology"
            },
            {
                "name": "Ganglian Yao",
                "org": "Department of Nephrology"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Nephrology"
            },
            {
                "name": "Haozhen Yuan",
                "org": "Department of Nephrology"
            },
            {
                "name": "Meiru Li",
                "org": "Department of Nephrology"
            },
            {
                "name": "Baosong Gui",
                "org": "Department of Nephrology"
            }
        ],
        "title": "Serum TGF-\u03b21 and Col III levels in patients with chronic kidney disease after oxymatrine treatment",
        "abstract": "Objective: To study the effects of oxymatrine on serum TGF- \u03b2",
        "keywords": [
            "Chronic kidney disease",
            "Collagen III (Col III)",
            "Oxymatrine",
            "Renal interstitial fibrosis",
            "Transforming growth factor-\u03b21 (TGF-\u03b21)"
        ],
        "venue": "Journal of Xi'an Jiaotong University (Medical Sciences)",
        "year": 2008,
        "id": "YCdsx9Wv"
    },
    "dx6Jd9xY": {
        "authors": [
            {
                "name": "Rong-Guo Fu",
                "org": "Nephrology Department"
            },
            {
                "name": "Xiao-Dan Liu",
                "org": "Nephrology Department"
            },
            {
                "name": "Cai-Xia Qi",
                "org": "Shaanxi Jinyu Pharmaceutical Corporation Ltd."
            },
            {
                "name": "Hao-Zheng Yuan",
                "org": "Anesthesiology Department"
            },
            {
                "name": "Feng Ma",
                "org": "Nephrology Department"
            },
            {
                "name": "Lin Zhou",
                "org": "Nephrology Department"
            },
            {
                "name": "Jun Zhang",
                "org": "Gastrointestinal Department"
            }
        ],
        "title": "Effect of ghrelin on migrating motor complex and Bcl-2/Bax expression in the duodenum of chronic renal dysfunction rats",
        "abstract": "Objective: To observe the effect of ghrelin on interdigestive migrating motor complex (MMC) and Bcl-2/Bax expression in the duodenum of chronic kidney dysfunction (CKD) rats. Methods: Totally 18 SD rats weighing (180 \u00b1 20) g were randomly divided into control group, ghrelin group 1 (CKD + ghrelin 10 \u03bcg/kg) and ghrelin group 2 (CKD + ghrelin 50 \u03bcg/kg), with 6 in each group. CKD rat model was set up in the latter two groups using 5/6 nephrectomy technique, then immunohistochemical staining was employed to detect the expressions of Bcl-2 and Bax in the duodenum, and multi-channel physical recorder machine was employed to recorder MMC of the duodenum. Results: The rats with CKD had disorder of motility in the duodenum. In control group, ghrelin group 1 and ghrelin group 2, ghrelin could significantly improve the time [(0.81 \u00b1 0.12) min vs. (0.84 \u00b1 0.13) min vs. (0.99 \u00b1 0.17) min], frequency [(22.68 \u00b1 1.00) min vs. (23.55 \u00b1 1.08) min vs. (29.31 \u00b1 1.51) min] and amplitude [(249.71 \u00b1 13.98) \u03bcV vs. (258.49 \u00b1 13.12) \u03bcV vs. (318.85 \u00b1 20.10) \u03bcV] of phase III in MMC of the duodenum (P < 0.05). Meanwhile, ghrelin down-regulated the expressions of Bcl-2 and Bax, especially that of Bax (P < 0.05), and then increased the ratio of Bcl-2/Bax (P < 0.05). Conclusion: Ghrelin can obviously improve motor function of CKD rat duodenum; therefore, it may be a new prokenetic drug.",
        "keywords": [
            "Bax",
            "Bcl-2",
            "Chronic kidney dysfunction",
            "Duodenum",
            "Ghrelin",
            "Migrating motor complex"
        ],
        "venue": "Journal of Xi'an Jiaotong University (Medical Sciences)",
        "year": 2011,
        "id": "dx6Jd9xY"
    },
    "tn25ugKy": {
        "authors": [
            {
                "name": "Mei-Ping Guan",
                "org": "Nanfang Hospital"
            },
            {
                "name": "Yao-Ming Xue",
                "org": "Nanfang Hospital"
            },
            {
                "name": "Jie Shen",
                "org": "Nanfang Hospital"
            },
            {
                "name": "Lin Zhou",
                "org": "Nanfang Hospital"
            },
            {
                "name": "Fang Gao",
                "org": "Nanfang Hospital"
            },
            {
                "name": "Chen-Zhong Li",
                "org": "Nanfang Hospital"
            }
        ],
        "title": "Relative factors of serum fat and uric acid change of type 2 diabetic patients and early prevention of stroke relapse",
        "abstract": "Objective: To investigate the change of serum and uric acid of type 2 diabetic patients concomitant with stroke. Methods: We selected 202 patients randomly, and divided them into 3 groups: diabetic concomitant with stroke group, simple stroke and simple diabetes group. We tested serum uric acid (UA) and serum fat of all patients and analysis its relationship with type 2 diabetes and stroke. Results: There was apparent difference in serum UA and HDL level between type 2 diabetic with stroke group and simple diabetic group. Conclusion: Decrease of HDL is one important risk factor for type 2 diabetic patients concomitant with stroke, and hypercuricemia is another important risk factor for male type 2 diabetic patients concomitant with stroke.",
        "keywords": [
            "High density lipoprotein cholesterol",
            "Stroke",
            "Type 2 diabetes mellitus",
            "Uric acid"
        ],
        "venue": "Chinese Journal of Clinical Rehabilitation",
        "year": 2002,
        "id": "tn25ugKy"
    },
    "AKWnozVp": {
        "authors": [
            {
                "name": "Yong Luo",
                "org": "Department of Plastic Surgery"
            },
            {
                "name": "Jian-Hua Gao",
                "org": "Department of Plastic Surgery"
            },
            {
                "name": "Fei Zhao",
                "org": "Department of Pathology"
            },
            {
                "name": "Bao Zhang",
                "org": "Department of Molecular Biology"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Molecular Biology"
            }
        ],
        "title": "Construction and quality analysis of subtracted cDNA libraries of keloid for the screening and clone of the keloid-related genes",
        "abstract": "Aim: To construct subtracted cDNA libraries of keloid so as to lay a foundation for screening and cloning specific keloid gene suppression. Methods: The experiment was conducted in the Institute of Gene Engineering, Southern Medical University form September 2003 to August 2004. The poly(A)",
        "keywords": [
            ""
        ],
        "venue": "Chinese Journal of Clinical Rehabilitation",
        "year": 2005,
        "id": "AKWnozVp"
    },
    "xWwFzSld": {
        "authors": [
            {
                "name": "Li-Juan Cui",
                "org": "Department of Traditional Chinese Medicine"
            },
            {
                "name": "Xiao-Shan Zhao",
                "org": "Department of Internal Medicine"
            },
            {
                "name": "Luo Ren",
                "org": "Department of Traditional Chinese Medicine"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Endocrinology"
            },
            {
                "name": "Yu-Ping Li",
                "org": "Department of Traditional Chinese Medicine"
            }
        ],
        "title": "Construction of relative genes library of kidney-yin deficiency of type 2 diabetic mellitus by using suppression subtractive hybridization",
        "abstract": "Aim: To construct the DNA subtractive library of kidney-yin deficiency of type 2 diabetic mellitus by using the technique of suppression subtractive hybridization, so as to provide theoretical references for establishing the primary and secondary rehabilitative preventions of type 2 diabetes mellitus. Methods: A patients with type 2 diabetes mellitus of Han nationality, who was treated in the Department of Endocrinology, Nanfang Hospital of Southern Medical University in August 2004, was involved in the study, The patient was in accordance with the diagnosis of classic kidney-yin deficiency in the traditional Chinese medicine diagnostic standards for kidney-yin deficiency, had normal liver and kidney functions, and had no acute or chronic infections. Another normal subject of the same gender and age at the same period was taken as the control voluntarily. The blood leucocyte DNA of the two subjects was extracted with the Maxim method by means of silica gel; After Rsa I enzyme restriction into segments of different size, it was connected with bonds of two different kinds respectively for twice subtractive hybridization and twice suppression polymerase chain reaction; The products of polymerase chain reaction was connected with the U/A vector, positive recombinant plasmid was screened by blue-white screening system and bacteria liquid polymerase chain reaction, and then the DNA subtractive library of kidney yin deficiency was constructed. The purity and content of extracted genome DNA, products of genome DNA Rsa I enzyme restriction, amplification results of the subtractive hybridization products, positive clone screened by blue-white screening system, and the recombinant plasmid screened by polymerase chain reaction were determined. Results: The different DNA segments of diabetic kidney yin deficiency were screened with the technique of suppression subtractive hybridization, after Rsa I enzyme restriction, the obtained genome DNA segments mainly concentrated in 200 to 2000 bp; After amplification of twice polymerase chain reaction, the products of subtractive hybridization were obviously increased, there were several scraps could be seen indistinctly inside, and mainly concentrated in 0.2 to 1.5 kb; Positive clones containing exogenous insert were screened by blue-white alpha complementation, and 286 and 262 clones were obtained with forward and backward subtractive hybridization products respectively; Ninety-two positive clones were randomly selected, and it was proved by polymerase chain reaction analysis that different DNA segments were observed in the plasmid of 86 clones, the sizes were 200 to 1 000 bp, and the DNA subtractive library of kidney yin deficiency of diabetes mellitus was set up successfully. Conclusion: Suppression subtractive hybridization can quickly and efficiently separate different DNA segments to construct the DNA subtractive library of kidney yin deficiency of diabetic mellitus, and it provides a foundation for further screening and cloning the related genes of kidney yin deficiency of diabetic mellitus.",
        "keywords": [
            ""
        ],
        "venue": "Chinese Journal of Clinical Rehabilitation",
        "year": 2005,
        "id": "xWwFzSld"
    },
    "wlsw6ZoT": {
        "authors": [
            {
                "name": "Ya Xiao",
                "org": "School of Traditional Chinese Medicine"
            },
            {
                "name": "Yanyan Liu",
                "org": "School of Traditional Chinese Medicine"
            },
            {
                "name": "Keqiang Yu",
                "org": "School of Traditional Chinese Medicine"
            },
            {
                "name": "Lin Zhou",
                "org": "Endocrinology Department"
            },
            {
                "name": "Jianlu Bi",
                "org": "School of Traditional Chinese Medicine"
            },
            {
                "name": "Jingru Cheng",
                "org": "School of Traditional Chinese Medicine"
            },
            {
                "name": "Fei Li",
                "org": "School of Traditional Chinese Medicine"
            },
            {
                "name": "Ren Luo",
                "org": "School of Traditional Chinese Medicine"
            },
            {
                "name": "Xiaoshan Zhao",
                "org": "School of Traditional Chinese Medicine"
            }
        ],
        "title": "The effect of Chinese herbal medicine on albuminuria levels in patients with diabetic nephropathy: A systematic review and meta-analysis",
        "abstract": "To evaluate the effect of Chinese herbal medicine (CHM) on albuminuria levels in patients with diabetic nephropathy (DN), we performed comprehensive searches on Medline database, Cochrane Library, CNKI database, CBM database, Wanfang database, and VIP database up to December 2012. A total of 29 trials including 2440 participants with DN met the selection criteria. CHM was tested to be more effective in reducing urinary albumin excretion rate (UAER) (MD -82.95 g/min, [-138.64, -27.26]) and proteinuria (MD -565.99 mg/24 h, [-892.41, -239.57]) compared with placebo. CHM had a greater beneficial effect on reduction of UAER (MD -13.41 g/min, [-20.63, -6.19]) and proteinuria (MD -87.48 mg/24 h, [-142.90, -32.06]) compared with angiotensin converting enzyme inhibitors (ACEI) or angiotensin receptor blockers (ARB). Combination therapy with CHM and ACEI/ARB showed significant improvement in UAER (MD -28.18 g/min, [-44.4, -11.97]), urinary albumin-creatinine ratio (MD -347.00, [-410.61, -283.39]), protein-creatinine ratio (MD -2.49, [-4.02, -0.96]), and proteinuria (MD -26.60 mg/24 h, [-26.73, -26.47]) compared with ACEI/ARB alone. No serious adverse events were reported. CHM seems to be an effective and safe therapy option to treat proteinuric patients with DN, suggesting that further study of CHM in the treatment of DN is warranted in rigorously designed, multicentre, large-scale trials with higher quality worldwide. \u00a9 2013 Ya Xiao et al.",
        "keywords": [
            ""
        ],
        "venue": "Evidence-based Complementary and Alternative Medicine",
        "year": 2013,
        "id": "wlsw6ZoT"
    },
    "lxT4xdJI": {
        "authors": [
            {
                "name": "Tian Wang",
                "org": "Department of Traditional Chinese Medicine, Nanfang Hospital, Southern Medical University"
            },
            {
                "name": "Jieyu Chen",
                "org": "Department of Traditional Chinese Medicine, Nanfang Hospital, Southern Medical University"
            },
            {
                "name": "Xiaomin Sun",
                "org": "School of Traditional Chinese Medicine, Southern Medical University"
            },
            {
                "name": "Lei Xiang",
                "org": "Department of Traditional Chinese Medicine, Nanfang Hospital, Southern Medical University"
            },
            {
                "name": "Lin Zhou",
                "org": "Endocrinology Department, Nanfang Hospital, Southern Medical University"
            },
            {
                "name": "Fei Li",
                "org": "Department of Traditional Chinese Medicine, Nanfang Hospital, Southern Medical University"
            },
            {
                "name": "Changsong Lin",
                "org": "Department of Rheumatic Diseases, First Affiliated Hospital, Nanfang Hospital, Guangzhou University of Chinese Medicine"
            },
            {
                "name": "Pingping Jiang",
                "org": "Department of Traditional Chinese Medicine, Nanfang Hospital, Southern Medical University"
            },
            {
                "name": "Shengwei Wu",
                "org": "Department of Traditional Chinese Medicine, Nanfang Hospital, Southern Medical University"
            },
            {
                "name": "Ya Xiao",
                "org": "Department of Traditional Chinese Medicine, Nanfang Hospital, Southern Medical University"
            },
            {
                "name": "Jingru Cheng",
                "org": "Department of Traditional Chinese Medicine, Nanfang Hospital, Southern Medical University"
            },
            {
                "name": "Ren Luo",
                "org": "Department of Traditional Chinese Medicine, Nanfang Hospital, Southern Medical University"
            },
            {
                "name": "Yanyan Liu",
                "org": "Department of Rheumatic Diseases, First Affiliated Hospital, Nanfang Hospital, Guangzhou University of Chinese Medicine"
            },
            {
                "name": "Xiaoshan Zhao",
                "org": "Department of Traditional Chinese Medicine, Nanfang Hospital, Southern Medical University"
            }
        ],
        "title": "Effects of TCMC on Transformation of Good Health Status to Suboptimal Health Status: A Nested Case-Control Study",
        "abstract": "To explore the effects of traditional Chinese medicine constitution (TCMC) on transformation of good health status to suboptimal health status (SHS), we conducted a nested case-control study among college students in China. During the 18-month mean follow-up time, 543 cases of SHS (42.7%) occurred in 1273 healthy students. There was a significant (P=0.000) and marked reduction in SHMS V1.0 total score in the case group at the 18-month follow-up (69.32 \u00b1 5.45) compared with baseline (78.60 \u00b1 4.70), but there was no significant change in the control group. Conditional logistic regression analysis showed that respondents reporting Yin-deficiency and Qi-deficiency were, respectively, 2.247 and 2.198 times more likely to develop SHS, while tendency to Yin-deficiency and tendency to Damp-heat were, respectively, 1.642 and 1.506 times more likely to develop SHS. However, the Balanced Constitution was a significant protective factor (OR 0.649; P<0.05). Altogether, these findings demonstrate that Yin-deficiency, Qi-deficiency, tendency to Yin-deficiency, and tendency to Damp-heat appeared to induce a change in health status to SHS, while the Balanced Constitution seemed to restrain this change. We conclude that regulating the unbalanced TCMC (such as Yin-deficiency and Qi-deficiency) may prevent a healthy status developing into SHS or lead to the regression of SHS.",
        "keywords": [
            ""
        ],
        "venue": "Evidence-based Complementary and Alternative Medicine",
        "year": 2015,
        "id": "lxT4xdJI"
    },
    "B4C1CIJi": {
        "authors": [
            {
                "name": "Yun-Hua Gong",
                "org": "Dept. of Opto-Electron. Info. Eng."
            },
            {
                "name": "Ping-An He",
                "org": "Dept. of Opto-Electron. Info. Eng."
            },
            {
                "name": "Lin Zhou",
                "org": "Dept. of Opto-Electron. Info. Eng."
            }
        ],
        "title": "On automatic interpretation of interference fringes",
        "abstract": "A new algorithm for automatic interpretation of interference fringes is proposed, which uses their own gray characters and design an appropriate weight function, then solves a series of curves to which the integrals of the square of the distance from each point of the fringes is minimal, that is to say, resolves expectation of fringes under the weight function designed. Furthermore the new algorithm has the functions of extracting the multiplicity of fringes as well as image processing. And the algorithm is insensitive to the random noise when the weight function is an odd function of gray of an image.",
        "keywords": [
            "Fringes interpretation",
            "Interference fringes",
            "Median axis transform",
            "Thinning algorithm",
            "Weight"
        ],
        "venue": "Guangdianzi Jiguang/Journal of Optoelectronics Laser",
        "year": 2002,
        "id": "B4C1CIJi"
    },
    "Bd5dXy46": {
        "authors": [
            {
                "name": "Yu-Min Zeng",
                "org": "Sch. of Phys. Sci. and Technology"
            },
            {
                "name": "Zhen-Yang Wu",
                "org": "Department of Radio Engineering"
            },
            {
                "name": "Hai-Bin Liu",
                "org": "Department of Radio Engineering"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Radio Engineering"
            }
        ],
        "title": "Modified AMDF pitch detection algorithm",
        "abstract": "A modified AMDF pitch detection algorithm is presented. The amplitude character of the basic AMDF of speech signal is modified by means of a simple linear transform in our algorithm. Then the pitch-point determining method, that taking the global minimum valley point of AMDF as the pitch period calculation point, can be employed in pitch detection, even for the voiced speech with good stability and periodicity. The simulated experiments indicate the performance is improved considerably relative to the conventional AMDF method.",
        "keywords": [
            "Average magnitude different function (AMDF)",
            "Pitch detection",
            "Speech signal processing"
        ],
        "venue": "International Conference on Machine Learning and Cybernetics",
        "year": 2003,
        "id": "Bd5dXy46"
    },
    "59X61emz": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "School of Electronic Information"
            },
            {
                "name": "Yong Ai",
                "org": "School of Electronic Information"
            },
            {
                "name": "Yun-Hua Gong",
                "org": "School of Electronic Information"
            }
        ],
        "title": "Improved target tracking algorithm for satellite laser communication system",
        "abstract": "Energy centroid algorithm is mostly used in center location of light spot, which is effected by the intensity distribution distortion of received light spot compared with that of light source. A distortion model is constructed, and a correcting factor is introduced. The related correcting algorithm is proposed, which modifies the conventional centroid algorithm. The correcting process applied in satellite laser communication is described. Computer simulation verifies that, under some factual circumstance, the angle deviations resulting from neglecting the asymmetrical attenuation of laser illumination can exceed 109\u2033. Therefore, in satellite laser communication, correcting factor introduced improves the locating and tracking precision and the channel reliability.",
        "keywords": [
            "Correcting factor",
            "Distortion",
            "Intensity centroid",
            "Satellite laser communication"
        ],
        "venue": "Hongwai yu Jiguang Gongcheng/Infrared and Laser Engineering",
        "year": 2004,
        "id": "59X61emz"
    },
    "d3mJUjXs": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Dept. of Radio Eng."
            },
            {
                "name": "Zhenyang Wu",
                "org": "Dept. of Radio Eng."
            }
        ],
        "title": "Joint GSM speech decoding algorithm based on MTD model",
        "abstract": "Joint source channel decoding algorithm based on parameter estimation with the time correlation of GSM (global system for mobile communication) EFR (enhanced full rate) encoded parameter is proposed. This algorithm utilizes MTD (mixture transition distribution) model to approximate high order Markov chain of parameter. Combined MTD model with likelihood value of received parameter provided by channel decoder, parameter is estimated according to MAP (maximum a posterior)/MS (minimum mean square)/delay-MS criterion. Simulation result shows that, for GSM EFR system, this method greatly improves the global SNR (signal to noise ratio) of parameter and speech compared with separate source channel decoding.",
        "keywords": [
            "Joint channel-source decoding",
            "MAP/MS delay-MS criterion",
            "MTD"
        ],
        "venue": "Dongnan Daxue Xuebao (Ziran Kexue Ban)/Journal of Southeast University (Natural Science Edition)",
        "year": 2004,
        "id": "d3mJUjXs"
    },
    "rDo16OXI": {
        "authors": [
            {
                "name": "Xian-Xing Liu",
                "org": ""
            },
            {
                "name": "Lian-Tang Zhang",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            }
        ],
        "title": "Synthesis method of circular array based on given pattern",
        "abstract": "On the basis of the given pattern, this paper systemically analyzes and researches synthesis method of circular array pattern. Regarding the minimum of the mean distance between given pattern and synthesized pattern as optimization rule, in the case of non-restraint, zero restraint or beam scan restraint, one can respectively gain relevant optimum excitation vectors. Various simulation results show that, this method is simple and efficient on improving the character of circular array pattern.",
        "keywords": [
            "Circular array",
            "Information processing",
            "Pattern",
            "Synthesis"
        ],
        "venue": "Tien Tzu Hsueh Pao/Acta Electronica Sinica",
        "year": 2005,
        "id": "rDo16OXI"
    },
    "UDrpZsH5": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Dept. of Radio Engineering"
            },
            {
                "name": "Zhen-Yang Wu",
                "org": "Dept. of Radio Engineering"
            }
        ],
        "title": "Iterative source-channel decoding for GSM",
        "abstract": "In speech signal transmission system, residual redundancy is still left in the parameters after source encoding. The redundancy includes non-uniform distribution and time correlation of subsequent frame. Exploiting the redundancy on bit-level, the paper is proposed iterative algorithm based on soft-in/soft-out channel and parameter estimation, and applies the algorithm to GSM EFR system. The result shows this method reduces the BER and improves SNR of decoded speech.",
        "keywords": [
            "Iterative decoding",
            "Parameter estimation",
            "Soft-in/soft-out decoder"
        ],
        "venue": "Dianzi Yu Xinxi Xuebao/Journal of Electronics and Information Technology",
        "year": 2005,
        "id": "UDrpZsH5"
    },
    "PxcBPgI7": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Institute of Applied Electronics"
            },
            {
                "name": "Huai-Bi Chen",
                "org": "Department of Engineering Physics"
            },
            {
                "name": "Zhou Xu",
                "org": "Institute of Applied Electronics"
            },
            {
                "name": "Shu-Xin Zheng",
                "org": "Department of Engineering Physics"
            },
            {
                "name": "Xiao-Zhong He",
                "org": "Department of Engineering Physics"
            }
        ],
        "title": "Computation for dispersion of gyro-TWT with a helical waveguide by MAFIA",
        "abstract": "This paper provides a simple technique to design and optimize the spiral waveguide of Gyro-TWT. The dispersion characteristic of helical waveguide was given out. The structure of waveguide was modeled by CAD and its dispersion curve was calculated by MAFIA using quasi-periodic boundary condition. The modes were calculated alternation 30\u00b0 phaseshift from -180\u00b0 to 180\u00b0. This method leads to a good agreement with the result of dispersion equation over 8.3 - 10.6 GHz, and the maximum relative deviation is below 0.5%. For a rather broad frequency band around the point where the longitudinal wavenumber is equal to zero, the slope of the dispersion curve trends to a positive constant. As a micro-wave amplifier, Gyro-TWT using spiral waveguide has a good potential in improving its effectiveness and increasing its bandwidth.",
        "keywords": [
            "Dispersion characteristics",
            "Gyro-TWT",
            "Helical waveguide",
            "MAFIA",
            "Model coupling"
        ],
        "venue": "Qiangjiguang Yu Lizishu/High Power Laser and Particle Beams",
        "year": 2005,
        "id": "PxcBPgI7"
    },
    "x8u5zLQT": {
        "authors": [
            {
                "name": "Xianxing Liu",
                "org": "College of Computer and Information Engineering"
            },
            {
                "name": "Lin Zhou",
                "org": "College of Computer and Information Engineering"
            },
            {
                "name": "Yong Jin",
                "org": "College of Computer and Information Engineering"
            }
        ],
        "title": "An algorithm of sensor management based on dynamic target detection",
        "abstract": "The probability density of stationary target is only evolved at measurement update, but the probability density of dynamic target is evolved not only at measurement update but also during measurements, this paper researches an algorithm of dynamic targets detection. Firstly, it presents the evolution of probability density at measurement update by Bayes' rule and the evolution of probability density during measurements by Fokker-Planck differential equations, respectively. Secondly, the method of obtaining information entropy by the probability density is given and sensor resources are distributed based on the evolution of information entropy viz. the maximization of information gain. Simulation results show that compared with the algorithm of serial search, this algorithm is feasible and effective when it is used to detect dynamic target.",
        "keywords": [
            "Dynamic target",
            "Information gain",
            "Probability density",
            "Sensor management",
            "Target detection"
        ],
        "venue": "Chinese Journal of Electronics",
        "year": 2005,
        "id": "x8u5zLQT"
    },
    "FJv68j3R": {
        "authors": [
            {
                "name": "Xian-Xing Liu",
                "org": "College of Computer and Information Engineering"
            },
            {
                "name": "Lin Zhou",
                "org": "College of Computer and Information Engineering"
            },
            {
                "name": "Xiao-Yu Du",
                "org": "College of Computer and Information Engineering"
            }
        ],
        "title": "Method of sensor management based on target priority and information gain",
        "abstract": "Information gain maximization is not sufficient condition but only necessary condition when it is used to distribute the sensor resources. In order to let sufficient condition be satisfied, this paper presents a method based on combining target priority with information gain. Based on information gain obtained by interacting multiple model (IMM), this method utilizes the method of partially order sets (POSET) to obtain the weights of different tasks such as detection, tracking and classifying. Sensor resources are reasonably distributed by combining information gain with the tasks priority. Simulation results show that compared with the method of information gain maximization, this method is better when it is used to distribute finite sensor resources, and it is a practical method.",
        "keywords": [
            "Grid",
            "Partially order sets (POSET)",
            "Sensor management information gain",
            "Target priority"
        ],
        "venue": "Tien Tzu Hsueh Pao/Acta Electronica Sinica",
        "year": 2005,
        "id": "FJv68j3R"
    },
    "LwNcz3Jz": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Dept. of Radio Engineering"
            },
            {
                "name": "Zhen-Yang Wu",
                "org": "Dept. of Radio Engineering"
            }
        ],
        "title": "Performance analysis of joint source-channel decoding based on MS estimation and iterative structure",
        "abstract": "Based on structure of MS estimation soft-bit source decoding and iterative source-controlled channel decoding, this paper deduces the parameter SNR and BER upper bound for above joint source-channel decoding respectively, and gives the factors which determine the improvement of system performance. The result shows the feasibility of joint source-channel decoding algorithm. Also, simulation proves the validity of analysis process.",
        "keywords": [
            "BER upper bound",
            "Joint source-channel decoding",
            "Parameter SNR"
        ],
        "venue": "Dianzi Yu Xinxi Xuebao/Journal of Electronics and Information Technology",
        "year": 2006,
        "id": "LwNcz3Jz"
    },
    "DVngkYds": {
        "authors": [
            {
                "name": "Ya-Xun Zhou",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Fen Chen",
                "org": ""
            },
            {
                "name": "Tie-Feng Xu",
                "org": ""
            },
            {
                "name": "Qiu-Hua Nie",
                "org": ""
            }
        ],
        "title": "Simulation analysis on gain competition among multi-channels of broad-band tellurite-based erbium-doped fiber amplifier",
        "abstract": "The simulation analyses on gain relations among multi-channels of novel broad-band erbium-doped tellurite-based fiber amplifier (EDTFA) are presented theoretically. The simulation results show that there is a gain competitive process among multi-channels which relied on the energy state population distribution of EDTFA. When the upper state population is reversed, the channel with greater difference of emission and absorption cross-section has bigger signal gain due to its competitive advantage. When the upper state population is not reversed, the channel with greater ratio of emission and absorption cross-section has greater competitive advantage.",
        "keywords": [
            "Erbium-doped tellurite-based fiber amplifier(EDTFA)",
            "Gain competition",
            "Population distribution"
        ],
        "venue": "Guangxue Jishu/Optical Technique",
        "year": 2006,
        "id": "DVngkYds"
    },
    "MPTOAZ56": {
        "authors": [
            {
                "name": "Xianxing Liu",
                "org": "College of Computer and Information Engineering"
            },
            {
                "name": "Fei Ding",
                "org": "Experimental Center"
            },
            {
                "name": "Zhentao Hu",
                "org": "College of Computer and Information Engineering"
            },
            {
                "name": "Lin Zhou",
                "org": "College of Computer and Information Engineering"
            }
        ],
        "title": "An adaptive filtering algorithm of noise variances based on modified \"current\" statistical model",
        "abstract": "The adaptive filtering algorithm based on current statistical model is introduced briefly. The paper analyses the influence of the limit acceleration and the variance of the measured error presupposed, and gives an improved adaptive filtering algorithm of noise variances self-adaptation. This algorithm establishes the adaptive adjustment between the covariance matrix of the maneuvering acceleration and the residual on the basis of the function relation of displacement and acceleration. Then, it utilizes maximum likelihood estimation algorithm and arithmetic mean method to obtain the on-line estimation of the variance of the measured error by the thought of spatial-temporal synthetical analysis. Finally, Monte-Carlo simulation shows that this algorithm can obviously improve the efficiency of maneuvering target tracking.",
        "keywords": [
            "\"Current\" statistical model",
            "Maneuvering target tracking",
            "State estimation"
        ],
        "venue": "Chinese Journal of Electronics",
        "year": 2006,
        "id": "MPTOAZ56"
    },
    "sKF2hB9Z": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Coll. of Computer and Information Engineering"
            },
            {
                "name": "Xian-Xing Liu",
                "org": "Coll. of Computer and Information Engineering"
            },
            {
                "name": "Yong Jin",
                "org": "Coll. of Computer and Information Engineering"
            }
        ],
        "title": "Method of sensor management in a nonlinear fusion system",
        "abstract": "For the dynamic tracking system which has stochastic state equation and nonlinear state or measurement equation non-Gaussian noise, a method of sensor management based on sequential Monte Carlo particle filtering is presented. Firstly, the covariance of targets is calculated by the method of particle filtering. Secondly, using the concept of information entropy, the information gain of targets is obtained. Finally, the sensor resources are allocated by maximizing the information gain. Simulation results show that this method is practical to the sensor management in a nonlinear system.",
        "keywords": [
            "Information entropy",
            "Information gain",
            "Nonlinear system",
            "Sensor management",
            "Target tracking"
        ],
        "venue": "Xi Tong Gong Cheng Yu Dian Zi Ji Shu/Systems Engineering and Electronics",
        "year": 2006,
        "id": "sKF2hB9Z"
    },
    "hiAYUer3": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "School of Mechatronics Engineering and Automation"
            },
            {
                "name": "Yi-Fan Dai",
                "org": "School of Mechatronics Engineering and Automation"
            },
            {
                "name": "Xu-Hui Xie",
                "org": "School of Mechatronics Engineering and Automation"
            },
            {
                "name": "Chang-Jun Jiao",
                "org": "School of Mechatronics Engineering and Automation"
            },
            {
                "name": "Sheng-Yi Li",
                "org": "School of Mechatronics Engineering and Automation"
            }
        ],
        "title": "Machining reachability in ion beam figuring",
        "abstract": "The conception and theoretical definition of machining reachability problem is proposed, and the existence condition of the solution of dwell time (DT) function is analyzed. Furthermore, we analyze and simulate the magnitude of the extra material removal (EMR) in different process condition using different ion beam diameter to remove different spatial frequency surface errors. The analysis results show that the solution of DT function exists for the ion beam removal functions of Gaussian shape. However, for the higher spatial frequency surface error, the larger the solution of DT function is, the larger the magnitude of the EMR is. The magnitude of EMR is an exponential function of the ratio of ion beam diameter to the spatial surface error wavelength (i.e. d/\u03bb). When d/\u03bb= 0.5, the EMR is 15%, which is acceptable in ion beam figuring process. When d/\u03bb = 1, it rapidly increases to 73%, which is unacceptable. Theoretical analysis and simulation results indicate that d/\u03bb should be less than 0.5 in order to obtain acceptable process in ion beam figuring.",
        "keywords": [
            "Computer controlled optical surfacing",
            "Dwell time",
            "Ion beam figuring",
            "Machining reachability",
            "Optics machining"
        ],
        "venue": "Guangxue Jingmi Gongcheng/Optics and Precision Engineering",
        "year": 2007,
        "id": "hiAYUer3"
    },
    "SJyYRroO": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "School of Mechatronic Engineering and Automation"
            },
            {
                "name": "Yi-Fan Dai",
                "org": "School of Mechatronic Engineering and Automation"
            },
            {
                "name": "Xu-Hui Xie",
                "org": "School of Mechatronic Engineering and Automation"
            },
            {
                "name": "Chang-Jun Jiao",
                "org": "School of Mechatronic Engineering and Automation"
            },
            {
                "name": "Sheng-Yi Li",
                "org": "School of Mechatronic Engineering and Automation"
            }
        ],
        "title": "Model and method to determine dwell time in ion beam figuring",
        "abstract": "To determine the dwell time is an important problem in ion beam figuring. Usually, the ion beam figuring process can be described by a two-dimensional convolution equation including dwell time and thus it can be solved theoretically by deconvolution. However, deconvolution is an ill-posed problem. Therefore the dwell time is difficult to be well solved. In order to solve the problem, a discrete linear model named CEH model was introduced and its advantages were discussed. And the truncated singular value decomposition (TSVD) method was proposed to solve the dwell time in CEH model. Furthermore, L-curve was introduced to analyze the relationship between the residual rms error and the material removal amount, and to evaluate the different picking methods of removal and dwell grid points in CEH model. Simulation results show that CEH model and TSVD method are suitable to determine the dwell time in optics fabrication using ion beam figuring.",
        "keywords": [
            "CEH model",
            "Ion beam figuring",
            "L-curve",
            "Optics fabrication",
            "Truncated singular value decomposition"
        ],
        "venue": "Nami Jishu yu Jingmi Gongcheng/Nanotechnology and Precision Engineering",
        "year": 2007,
        "id": "SJyYRroO"
    },
    "zPbX7m6Q": {
        "authors": [
            {
                "name": "Wen-Jun Li",
                "org": "Institute of Applied Electronics"
            },
            {
                "name": "Zhou Xu",
                "org": "Institute of Applied Electronics"
            },
            {
                "name": "Yu-Zheng Lin",
                "org": "Department of Engineering Physics"
            },
            {
                "name": "Xiao Jin",
                "org": "Institute of Applied Electronics"
            },
            {
                "name": "Ming Li",
                "org": "Institute of Applied Electronics"
            },
            {
                "name": "Xing-Fan Yang",
                "org": "Institute of Applied Electronics"
            },
            {
                "name": "Lin Zhou",
                "org": "Institute of Applied Electronics"
            }
        ],
        "title": "Design and large-signal beam-wave interaction research of coupled-cavity traveling-wave tube",
        "abstract": "An important characteristic of the beam-wave interaction in traveling-wave tube is that the velocity modulation and bunching of electron beam, also its energy exchange with the RF field, happen continuously and simultaneously along the whole slow-wave structure. This is why traveling wave tube can offer large output power in a very broad band. On the basis of cold cavity characteristic research, quantitative analysis of the large signal beam-wave interaction of coupled-cavity traveling-wave tube is performed using three-dimensional PIC simulation code. In addition, an X-band CW coupled-cavity traveling-wave tube is designed with the design parameters as follows: operating frequency from 7.1 GHz to 8.5 GHz, bandwidth 18%, the highest output power of 3kW.",
        "keywords": [
            "Cold cavity characteristic",
            "Coupled-cavity traveling-wave tube",
            "CW",
            "Large-signal beam-wave interaction",
            "PIC simulation",
            "X-band"
        ],
        "venue": "Dianzi Yu Xinxi Xuebao/Journal of Electronics and Information Technology",
        "year": 2007,
        "id": "zPbX7m6Q"
    },
    "OAvYMaRl": {
        "authors": [
            {
                "name": "Hao Ma",
                "org": "School of Information Science and Engineering"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Information Science and Engineering"
            },
            {
                "name": "Hong-Mei Hu",
                "org": "School of Information Science and Engineering"
            },
            {
                "name": "Zhen-Yang Wu",
                "org": "School of Information Science and Engineering"
            }
        ],
        "title": "Head related transfer function based neural network sound localization",
        "abstract": "Machine intelligence requires convenient and effective estimation mode for sound localization. According to the tight relation of Head Related Transfer Function (HRTF) and location, this paper studies a sound localization method based on HRTF. Using the forward neural network, the direction information is extracted and multi coded in parallel, and then is weighted to estimate the sound position. Simulations show that the method is more accurate and compact. Finally, robust analysis is given to prove validity of simulation results.",
        "keywords": [
            "Head Related Transfer Function (HRTF)",
            "Neural network",
            "Robust analysis",
            "Sound localization",
            "Weighted estimation"
        ],
        "venue": "Dianzi Yu Xinxi Xuebao/Journal of Electronics and Information Technology",
        "year": 2007,
        "id": "OAvYMaRl"
    },
    "jUkQq0PU": {
        "authors": [
            {
                "name": "Chang-Jun Jiao",
                "org": "School of Mechanic Engineering and Automation"
            },
            {
                "name": "Sheng-Yi Li",
                "org": "School of Mechanic Engineering and Automation"
            },
            {
                "name": "Deng-Feng Wang",
                "org": "School of Mechanic Engineering and Automation"
            },
            {
                "name": "Xu-Hui Xie",
                "org": "School of Mechanic Engineering and Automation"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Mechanic Engineering and Automation"
            }
        ],
        "title": "Material removal property in ion figuring process for optical components",
        "abstract": "The material removal property with three important performance factors, the material removal efficiency, depth of the sub-surface damage and thermal effect, in the ion figuring process was analyzed. Based on the Sigmund sputtering theory, the relation models of these three factors with respect to ion energy and incident angle were established. The sputtering process of SiO",
        "keywords": [
            "Ion sputtering",
            "Optical component",
            "Removal efficiency",
            "Sub-surface damage",
            "Thermal effect"
        ],
        "venue": "Guangxue Jingmi Gongcheng/Optics and Precision Engineering",
        "year": 2007,
        "id": "jUkQq0PU"
    },
    "fbQ3OkmK": {
        "authors": [
            {
                "name": "Wen-Jun Li",
                "org": "Chinese Academy of Engineering Physics"
            },
            {
                "name": "Zhou Xu",
                "org": "Chinese Academy of Engineering Physics"
            },
            {
                "name": "Yu-Zheng Lin",
                "org": "Department of Engineering Physics"
            },
            {
                "name": "Ming Li",
                "org": "Chinese Academy of Engineering Physics"
            },
            {
                "name": "Xing-Fan Yang",
                "org": "Chinese Academy of Engineering Physics"
            },
            {
                "name": "Lin Zhou",
                "org": "Chinese Academy of Engineering Physics"
            },
            {
                "name": "Xiao Jin",
                "org": "Chinese Academy of Engineering Physics"
            }
        ],
        "title": "Three-dimensional whole-tube simulation of coupled-cavity traveling-wave tube",
        "abstract": "Electron gun is one of the key components of coupled-cavity traveling-wave tube (TWT). Its electron beam parameters have important influence on TWT performances. As a result, electron gun was firstly simulated when an S-band coupled-cavity TWT was designed using PIC software. Then, the three-dimensional simulation model of whole TWT was constructed, which consists of electron gun, slow-wave structure, microwave input and output coupler, etc. Finally, the large signal beam-wave interaction of the whole S-band TWT was simulated. Results show that the continuous wave output power reaches 5.9 kW and the efficiency reaches 24% in the operating frequency range of 2.0-2.3 GHz. Whole-tube simulation provides reference for TWT design.",
        "keywords": [
            "Beam-wave interaction",
            "Coupled-cavity traveling-wave tube",
            "PIC simulation",
            "Whole-tube simulation"
        ],
        "venue": "Yuanzineng Kexue Jishu/Atomic Energy Science and Technology",
        "year": 2007,
        "id": "fbQ3OkmK"
    },
    "SlKmSuQT": {
        "authors": [
            {
                "name": "Hongmei Hu",
                "org": "Coliege of Mechanical Engineering"
            },
            {
                "name": "Lin Zhou",
                "org": "College of Information Science and Engineering"
            },
            {
                "name": "Jie Zhang",
                "org": "College of Information Science and Engineering"
            },
            {
                "name": "Hao Ma",
                "org": "College of Information Science and Engineering"
            },
            {
                "name": "Zhenyang Wu",
                "org": "College of Information Science and Engineering"
            }
        ],
        "title": "Head related transfer function personalization based on multiple regression analysis",
        "abstract": "The synthesis of personalization virtual auditory space (VAS) is an important and challenging task in virtual reality. One of the key factors for personalization VAS is to obtain a set of proper head related transfer functions (HRTFs). In this paper, a customization method is presented by applying multiple linear regression analysis to HRTFs and some anthropometric parameters chosen by correlation analysis. Experiments show that the estimated HRTF has small mean square error, and has similar perception effect as the measured HRTF. Furthermore, the localization accuracy of personalized HRTF is increased compared to the non-individual HRTF. \u00a9 2006 IEEE.",
        "keywords": [
            ""
        ],
        "venue": "2006 International Conference on Computational Intelligence and Security, ICCIAS 2006",
        "year": 2007,
        "id": "SlKmSuQT"
    },
    "nXVnF9md": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Dept. of Mechatronic Engineering"
            },
            {
                "name": "Xuhui Xie",
                "org": "Dept. of Mechatronic Engineering"
            },
            {
                "name": "Yifan Dai",
                "org": "Dept. of Mechatronic Engineering"
            },
            {
                "name": "Changjun Jiao",
                "org": "Dept. of Mechatronic Engineering"
            },
            {
                "name": "Shengyi Li",
                "org": "Dept. of Mechatronic Engineering"
            }
        ],
        "title": "Ion beam figuring system in NUDT",
        "abstract": "Ion beam figuring (IBF) is an optical fabrication technique that provides highly deterministic process to correct surface figure error of previously polished surfaces by using a directed, inert and neutralized ion beam to physically sputter material from the optic surface. Recently, an ion beam figuring system KDIFS-500 has been designed and built in National University of Defense Technology (NUDT) of the P.R. China. KDIFS-500 is capable of processing workpiece up to \u03c6500mm. Line scanning process was discussed in detail for estimating the parameters of the beam removal function (BRF) in process. Experiments were conducted to demonstrate that the BRF increases gradually in process and by employing a stability control, the BRF can be kept stable in process. Finally, a \u03c695 mm piano optical sample of CVD coated SiC substrate has been figured in two process iterations for demonstrating the correction capability of the KDIFS-500. Their figure convergence ratios reached 5.8 and 2.1 respectively. The actual figure residual errors were basically consistent with the predicted error. These consistencies indicated that the IBF processes on KDIFS-500 are predictable deterministic processes.",
        "keywords": [
            "Beam removal function",
            "Deterministic process",
            "Ion beam figuring",
            "Line scanning process",
            "Stability control"
        ],
        "venue": "Proceedings of SPIE - The International Society for Optical Engineering",
        "year": 2007,
        "id": "nXVnF9md"
    },
    "LoIbxGbi": {
        "authors": [
            {
                "name": "Xian-Xing Liu",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Xiao-Yu Du",
                "org": ""
            }
        ],
        "title": "Algorithm of sensor management based on RIMMKF",
        "abstract": "This paper presents an algorithm of sensor management based on reweighted interacting multiple models Kalman filtering (RTMMKF). In this algorithm, discrimination via information gain is obtained by measurement update and Markov transform update of joint multi-target probability using RTMM, and then the sensor resource is distributed by maximizing information gain. In this algorithm, the deficiency of interacting multiple models (EMM) is improved by RIMM. Simulation results show that compared with the method of IMMKF discrimination, this algorithm is reasonable and the sensor resource is effectively distributed under the circumstance of dynamic multiple models.",
        "keywords": [
            "Discrimination",
            "Information gain",
            "Reweighted interacting multiple models Kalman filtering (RIMMKF)",
            "Sensor management"
        ],
        "venue": "Tien Tzu Hsueh Pao/Acta Electronica Sinica",
        "year": 2007,
        "id": "LoIbxGbi"
    },
    "4H9NJfve": {
        "authors": [
            {
                "name": "Hao Ma",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Hongmei Hu",
                "org": ""
            },
            {
                "name": "Zhenyang Wu",
                "org": ""
            }
        ],
        "title": "A novel sound localization method based on head related transfer function",
        "abstract": "In machine sound localization, convenient and effective estimation modes are required. A dummy head with certain head related transfer function (HRTF) can be introduced to sound localization instead of the conventional microphone array or other sensor systems. Since the spectrum of HRTF varies with the sound source direction, a sound localization method based on spectral cues is presented. By simplifying the direction estimation process of human spatial hearing, the directional information is extracted from the spectrum of HRTF and is multi coded in parallel with a feed forward neural network. Then the multi coded directional information is weighted to estimate the sound position. Simulations show that the proposed method is effective. \u00a9 2007 IEEE.",
        "keywords": [
            "Dummy head",
            "Head related transfer function (HRTF)",
            "Machine sound localization",
            "Neural network",
            "Weighted estimation"
        ],
        "venue": "2007 8th International Conference on Electronic Measurement and Instruments, ICEMI",
        "year": 2007,
        "id": "4H9NJfve"
    },
    "uIpazmLg": {
        "authors": [
            {
                "name": "Hong-Mei Hu",
                "org": "School of Mechanical Engineering"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Information Science and Engineering"
            },
            {
                "name": "Hao Ma",
                "org": "School of Information Science and Engineering"
            },
            {
                "name": "Zhen-Yang Wu",
                "org": "School of Information Science and Engineering"
            }
        ],
        "title": "Head-related transfer function personalization based on partial least square regression",
        "abstract": "A method is proposed to obtain individual Head Related Transfer Function (HRTF) based on the Partial Least Square Regression (PLSR), in which anthropometric parameters are selected by correlation analysis and the original HRTF data, are preprocessed before principal component analysis. Then objective simulation experiment and subjective sound localization experiment are implemented to evaluate the method. The experiments show that the estimated HRTF not only has small mean square error, but also has little perception difference from the measured one; the localization performance of the individual HRTF estimated by PLSR presented in this article is more accurate than that of the non-individual HRTF obtained from the database and also more accurate than that estimated via Least Square Regression (LSR).",
        "keywords": [
            "Head related transfer function",
            "Least square regression",
            "Partial least square regression",
            "Sound localization experiment"
        ],
        "venue": "Dianzi Yu Xinxi Xuebao/Journal of Electronics and Information Technology",
        "year": 2008,
        "id": "uIpazmLg"
    },
    "BTNUjOVB": {
        "authors": [
            {
                "name": "Hongmei Hu",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Hao Ma",
                "org": ""
            },
            {
                "name": "Feiran Yang",
                "org": ""
            },
            {
                "name": "Zhenyang Wu",
                "org": ""
            }
        ],
        "title": "Externalization of headphone-based virtual sound system",
        "abstract": "An externalized virtual sound localization system based on personalized binaural room impulse response (PBRIR) is proposed to simulate spatial hearing environment. To obtain the PBRIR, personalized head related transfer functions (HRTFs) were used in the image method. First, personalized HRTFs were obtained via the anthropometrics measurement; secondly, image method was applied to obtain the first four-order personalized reflections; finally, only the first 80ms of those reflections were remained as the PBRIR. Subjective listening experiments were designed and the results show that out-of-head localization can be obtained without decreasing the localization accuracy when the dummy head binaural room impulse response (BRIR) is used. When the PBRIR is used, the out-of-head localization is improved, and the localization accuracy is increased of about 13 percent.",
        "keywords": [
            "Binaural room impulse response",
            "Head related transfer functions",
            "Image method",
            "Virtual sound system"
        ],
        "venue": "Dongnan Daxue Xuebao (Ziran Kexue Ban)/Journal of Southeast University (Natural Science Edition)",
        "year": 2008,
        "id": "BTNUjOVB"
    },
    "bsQkwQQ0": {
        "authors": [
            {
                "name": "Hao Ma",
                "org": "School of Information Science and Engineering"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Information Science and Engineering"
            },
            {
                "name": "Hongmei Hu",
                "org": "School of Information Science and Engineering"
            },
            {
                "name": "Zhenyang Wu",
                "org": "School of Information Science and Engineering"
            }
        ],
        "title": "Adaptive cascade inverse filter design for crosstalk cancellation system",
        "abstract": "To simplify the crosstalk cancellation block in sound rendering systems, the scheme of cascade inverse filter is proposed. By analyzing the impulse response and the frequency response of the loudspeaker transfer functions of different channels, a common inverse filter is designed to compensate the similar part of the loudspeaker transfer functions. Based on this, a corresponding adaptive algorithm for cascade structure is deduced. By reduction of inverse operation, the efficiency of the filter in each channel is improved. With the same amount of the coefficients, the proposed cascade structure has extended the average channel separation at best about 6 dB comparing with the conventional structure, thus has a more satisfactory performance. Computer simulation and experimental tests in real environment show that the proposed scheme effectively reduces the filter parameters with acceptable performance for crosstalk cancellation.",
        "keywords": [
            "Adaptive algorithm",
            "Cascade structure",
            "Crosstalk cancellation",
            "Inverse filter design",
            "Sound rendering"
        ],
        "venue": "Dongnan Daxue Xuebao (Ziran Kexue Ban)/Journal of Southeast University (Natural Science Edition)",
        "year": 2008,
        "id": "bsQkwQQ0"
    },
    "8uDdGEnD": {
        "authors": [
            {
                "name": "Hongmei Hu",
                "org": "School of Mechanical Engineering"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Information Science and Engineering"
            },
            {
                "name": "Hao Ma",
                "org": "School of Information Science and Engineering"
            },
            {
                "name": "Zhenyang Wu",
                "org": "School of Information Science and Engineering"
            }
        ],
        "title": "HRTF personalization based on artificial neural network in individual virtual auditory space",
        "abstract": "The synthesis of individual virtual auditory space (VAS) is an important and challenging task in virtual reality. One of the key factors for individual VAS is to obtain a set of individual head related transfer functions (HRTFs). A customization method based on back-propagation (BP) artificial neural network (ANN) is proposed to obtain an individual HRTF without complex measurement. The inputs of the neural network are the anthropometric parameters chosen by correlation analysis and the outputs are the characteristic parameters of HRTFs together with the interaural time difference (ITD). Objective simulation experiments and subjective sound localization experiments are implemented to evaluate the performance of the proposed method. Experiments show that the estimated non-individual HRTF has small mean square error, and has similar perception effect to the corresponding one obtained from the database. Furthermore, the localization accuracy of personalized HRTF is increased compared to the non-individual HRTF. \u00a9 2007 Elsevier Ltd. All rights reserved.",
        "keywords": [
            "Artificial neural network",
            "Head related impulse response",
            "Head related transfer function",
            "Interaural time difference",
            "Sound localization",
            "Virtual auditory space"
        ],
        "venue": "Applied Acoustics",
        "year": 2008,
        "id": "8uDdGEnD"
    },
    "qbjLbIBR": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "College of Mechatronic Engineering and Automation"
            },
            {
                "name": "Yifan Dai",
                "org": "College of Mechatronic Engineering and Automation"
            },
            {
                "name": "Xuhui Xie",
                "org": "College of Mechatronic Engineering and Automation"
            },
            {
                "name": "Changjun Jiao",
                "org": "College of Mechatronic Engineering and Automation"
            },
            {
                "name": "Shengyi Li",
                "org": "College of Mechatronic Engineering and Automation"
            }
        ],
        "title": "Analysis of correcting ability of ion beam figuring",
        "abstract": "In ion beam figuring process, typically, the smaller ion beam diameter has a good ability to \"correct\" the optical surface error, i.e. the smaller ion beam diameter indicates the higher material removal efficiency \u03b5. The material removal efficiency is defined as the ratio of the volume of desired material removal to that of the real material removal. However the smaller ion beam diameter always results in more processing time, which usually decreases the process reliability. In this paper, the relationship between the material removal efficiency and the ion beam diameter is analyzed. The theoretical result shows that the material removal efficiency is a negative exponential function of the ratio of ion beam diameter to the spatial error wavelength, (i.e. d/\u03bb). And when d/\u03bb= 0.5, the material removal efficiency is 87%, which is acceptable in ion beam figuring process. When d/\u03bb = 1, it rapidly decreases to 58%, which is unacceptable. According to theoretical analysis and simulation results, we recommend that d/\u03bb should be less than 0.5 in order to obtain acceptable material removal efficiency in ion beam figuring process.",
        "keywords": [
            "Correcting ability",
            "Ion beam diameter",
            "Ion beam figuring",
            "Material removal efficiency",
            "Optics manufacture"
        ],
        "venue": "Key Engineering Materials",
        "year": 2008,
        "id": "qbjLbIBR"
    },
    "TpMavis7": {
        "authors": [
            {
                "name": "Changjun Jiao",
                "org": "College of Mechatronic Engineering and Automation"
            },
            {
                "name": "Xuhui Xie",
                "org": "College of Mechatronic Engineering and Automation"
            },
            {
                "name": "Shengyi Li",
                "org": "College of Mechatronic Engineering and Automation"
            },
            {
                "name": "Lin Zhou",
                "org": "College of Mechatronic Engineering and Automation"
            },
            {
                "name": "Yifan Dai",
                "org": "College of Mechatronic Engineering and Automation"
            }
        ],
        "title": "Design of ion beam figuring machine for optical mirrors",
        "abstract": "Ion beam Figuring (IBF) of optical mirror is a polishing process based on CCOS with the application of ion sputtering effects. The material removal mechanism is in the atom scale, which can enhance the precision of the target surface to tens of nanometers. Without contact, this process can also promote the subsurface quality. In this paper, the Ion Beam Figuring Machine (IBFM) is introduced, which realizes the relative motion between the target surface and the ion source. Firstly, we describe the design method, the machine configuration and principal technical parameters. With the configuration and motion ability described, we introduce different scanning modes for surfaces of different scales respectively. Secondly presented is the precision analysis method for IBFM. Based on the CCOS principle, the relation between the convergence rate and positioning errors are deduced. This relation describes the precision requirement of machining process. Finally, the postposition algorithm of IBFM is analyzed. According to coordinate transition and rotation, the general transfer model for different scanning modes is given.",
        "keywords": [
            "Ion-beam figuring",
            "Machine design",
            "Postposition algorithm",
            "Precision analysis"
        ],
        "venue": "Key Engineering Materials",
        "year": 2008,
        "id": "TpMavis7"
    },
    "2VJzl3xi": {
        "authors": [
            {
                "name": "Changjun Jiao",
                "org": "National University of Defense Technology"
            },
            {
                "name": "Shengyi Li",
                "org": "National University of Defense Technology"
            },
            {
                "name": "Xuhui Xie",
                "org": "National University of Defense Technology"
            },
            {
                "name": "Lin Zhou",
                "org": "National University of Defense Technology"
            }
        ],
        "title": "Design and analysis of ion beam figuring machine for optics components",
        "abstract": "The post-algorithm and error compensation were discussed. The direct kinetic algorithm of KDIFS-500 was set up based on DH method, and followed by the error model with respect to positioning errors and assemble errors of ion source and workpiece. The prominent influence of the deterministic assembly error of the ion source in the tangent plane would be canceled with an error compensation matrix. Thorough analysis of the error model with compensation matrix, it is indicated that the influence of the positioning error along the trajectory of the ion beam and that of the incidence angle error on the figuring process can be ignored with the constraints applied by satisfaction with the demand of the positioning error in the tangent plane.",
        "keywords": [
            "Error compensation",
            "Error model",
            "Ion beam figuring",
            "Post-algorithm"
        ],
        "venue": "Zhongguo Jixie Gongcheng/China Mechanical Engineering",
        "year": 2008,
        "id": "2VJzl3xi"
    },
    "VR1AEQZ3": {
        "authors": [
            {
                "name": "Yifan Dai",
                "org": "Department of Mechatronics Engineering"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Mechatronics Engineering"
            },
            {
                "name": "Xuhui Xie",
                "org": "Department of Mechatronics Engineering"
            },
            {
                "name": "Changjun Jiao",
                "org": "Department of Mechatronics Engineering"
            },
            {
                "name": "Shengyi Li",
                "org": "Department of Mechatronics Engineering"
            }
        ],
        "title": "Deterministic figuring in optical machining by ion beam",
        "abstract": "Ion beam figuring (IBF) is introduced to overcome the disadvantages of conventional polishing processes in optical machining. The principle and method of IBF are introduced, and the key techniques required to implement an IBF process are also discussed. To demonstrate an IBF process, a \u03c698 mm planar ceramic glass was processed on an IBF system. Its surface figure accuracy root-mean-square (RMS) is improved from initial 0.136\u03bb to final 0.010\u03bb(\u03bb=632.8 nm) through two IBF processes, and the mean iterative convergence ratio is 3.7. The result shows that the IBF is a deterministic process, which results in a high surface figure accuracy without edge effect and a corresponding high convergence ratio of surface figure. Due to the unique characteristic of the sputtering process in IBF, machining an aspheric surface is no more difficult than machining a planar surface.",
        "keywords": [
            "Computer-controlled optical surfacing",
            "Dwell time",
            "Ion beam figuring",
            "Optical machining",
            "Removal function"
        ],
        "venue": "Guangxue Xuebao/Acta Optica Sinica",
        "year": 2008,
        "id": "VR1AEQZ3"
    },
    "IuY1Ta6d": {
        "authors": [
            {
                "name": "Ziyang Wang",
                "org": "Key Laboratory of Land Regulation"
            },
            {
                "name": "Kening Wu",
                "org": "Key Laboratory of Land Regulation"
            },
            {
                "name": "Caixia Rao",
                "org": "Key Laboratory of Land Regulation"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Land Regulation"
            },
            {
                "name": "Lin Xu",
                "org": "Key Laboratory of Land Regulation"
            }
        ],
        "title": "Application of agricultural land classification to requisition-compensation balance of arable land",
        "keywords": [
            "Agricultural land classification",
            "Grade conversion coefficient",
            "Requisition-compensation balance of arable land"
        ],
        "venue": "Nongye Gongcheng Xuebao/Transactions of the Chinese Society of Agricultural Engineering",
        "year": 2008,
        "id": "IuY1Ta6d"
    },
    "XuaQHIpp": {
        "authors": [
            {
                "name": "Caixia Rao",
                "org": "Key Laboratory of Land Regulation"
            },
            {
                "name": "Kening Wu",
                "org": "Key Laboratory of Land Regulation"
            },
            {
                "name": "Lin Xu",
                "org": "Key Laboratory of Land Regulation"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Land Regulation"
            },
            {
                "name": "Ziyang Wang",
                "org": "Key Laboratory of Land Regulation"
            }
        ],
        "title": "Transfer problems in the process of farmland classification from provincial results to national rank",
        "keywords": [
            "Balanced transfer",
            "Farmland",
            "Farmland classification",
            "Usage classification index"
        ],
        "venue": "Nongye Gongcheng Xuebao/Transactions of the Chinese Society of Agricultural Engineering",
        "year": 2008,
        "id": "XuaQHIpp"
    },
    "sfMalQcM": {
        "authors": [
            {
                "name": "Chang-Jun Jiao",
                "org": "School of Mechanical Engineering and Automation"
            },
            {
                "name": "Xu-Hui Xie",
                "org": "School of Mechanical Engineering and Automation"
            },
            {
                "name": "Sheng-Yi Li",
                "org": "School of Mechanical Engineering and Automation"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Mechanical Engineering and Automation"
            }
        ],
        "title": "Material removal efficiency in ion beam figuring for optical component",
        "abstract": "The removal efficiency and the relative removal efficiency between two different materials and three performance factors, normal removal rate, volume removal rate and sputtering yield, were analyzed in ion beam figuring process. With the Sigmund sputtering theory, the relation models between three factors and processing parameters, such as ion energy, ion flux and ion incident angle, were established. The experiments with samples of zerodur, SiO\n                        ",
        "keywords": [
            "Ion beam figuring",
            "Ion sputtering",
            "Material removal efficiency",
            "Optical fabrication"
        ],
        "venue": "Guangxue Jingmi Gongcheng/Optics and Precision Engineering",
        "year": 2008,
        "id": "sfMalQcM"
    },
    "Dj3vVy5L": {
        "authors": [
            {
                "name": "Chang-Jun Jiao",
                "org": "School of Mechanics Engineering and Automation"
            },
            {
                "name": "Sheng-Yi Li",
                "org": "School of Mechanics Engineering and Automation"
            },
            {
                "name": "Xu-Hui Xie",
                "org": "School of Mechanics Engineering and Automation"
            },
            {
                "name": "Deng-Feng Wang",
                "org": "School of Mechanics Engineering and Automation"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Mechanics Engineering and Automation"
            }
        ],
        "title": "Controllability of removal function in the ion beam figuring process for optics mirrors",
        "abstract": "The processing controllability of the removal function is analyzed experimentally and. then figuring experiment is made on the plane sample of K4. The demands on the removal function are deduced from the CCOS principle. Three factors CFWHM, volume removal rate and peak removal rate are presented to evaluate the properties of the removal function, which are the long-time stability, time linearity, robust with respect to little disturbance of process parameters. The influences of parameters adjustment in large scale on the removal function are analyzed. Based on the results on the removal function, the \u03a6100 mm K4 sample is figured with ion beam. With three iterations, the surface error is reduced from 0.149\u03bb RMS to 0.013\u03bb RMS. The experimental results indicate that the removal function can hold a long-time stability, scale with time, have robust with respect to little disturbance. The width and removal rate can be modulated by process parameters. Ion beam figuring is a technique of high efficiency.",
        "keywords": [
            "Ion beam figuring",
            "Processing controllability",
            "Removal function",
            "Stability"
        ],
        "venue": "Guangxue Jishu/Optical Technique",
        "year": 2008,
        "id": "Dj3vVy5L"
    },
    "oaiCGxbo": {
        "authors": [
            {
                "name": "Xuhui Xie",
                "org": ""
            },
            {
                "name": "Dengfeng Wang",
                "org": ""
            },
            {
                "name": "Changjun Jiao",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            }
        ],
        "title": "Influence of the parameters of ion beam on the removal function in IBF process",
        "abstract": "In IBF process, the ability and efficiency of figuring are mainly lain on the characteristics of removal function. This paper focused on the influence of the parameters of Kaufman ion source on the removal function by experiment test, and illustrated the changing law of the removal function further. Through these experiments, conclusions can be drew as following. Accelerating-grid and neutralizing cathode have little influence on the removal function when voltages vary in some range. An removal function with bigger diameter can be acquired with higher voltage and current of the screen-grid, higher gas flow rate, and higher screen-grid voltage. On the other hand, the diameter of removal function will become smaller with lower the screen-grid current and lower gas flow rate. So, we can control the parameters of removal function by changing the parameters of ion beam figuring the spatial frequency errors of optics.",
        "keywords": [
            "Ion beam figuring (IBF)",
            "Parameters of ion beam",
            "Removal function"
        ],
        "venue": "Yi Qi Yi Biao Xue Bao/Chinese Journal of Scientific Instrument",
        "year": 2008,
        "id": "oaiCGxbo"
    },
    "cGzHsK1V": {
        "authors": [
            {
                "name": "Xiao-Zhou Ye",
                "org": "Accelerator Laboratory"
            },
            {
                "name": "Zheng Yang",
                "org": "Accelerator Laboratory"
            },
            {
                "name": "Lin Zhou",
                "org": "Accelerator Laboratory"
            },
            {
                "name": "Zhong-Liang Ouyang",
                "org": "Accelerator Laboratory"
            },
            {
                "name": "Ming Li",
                "org": "Accelerator Laboratory"
            },
            {
                "name": "Chuan-Sheng Liu",
                "org": "Accelerator Laboratory"
            },
            {
                "name": "Li-Ping Guo",
                "org": "Accelerator Laboratory"
            },
            {
                "name": "Feng Ren",
                "org": "Accelerator Laboratory"
            },
            {
                "name": "Chang-Zhong Jiang",
                "org": "Accelerator Laboratory"
            },
            {
                "name": "De-Jun Fu",
                "org": "Accelerator Laboratory"
            }
        ],
        "title": "Optics calculation and beam line design for accelerator-tem interface",
        "abstract": "Accelerator-transmission electron microscopy(TEM) interface facility is a useful tool for the study of materials because of its in situ observation function that is applicable to the complex evolution of microstructures during ion irradiation. The first accelerator-TEM interface system in China has been established at Wuhan University, which consists of a Hitachi H800 TEM, a 200 kV ion implanter and a 2\u00d71.7 MV tandem accelerator. The paper gives the layout of the equipment and ion optical calculation results which provide possible adjustment of the system to improve its performance. The calculation result suggests that transport efficiency of the ion beam can be enhanced by adding another duality electrostatic quadruple in company with adjusting the original magnetic quadrupoles.",
        "keywords": [
            "Accelerator",
            "Beam line",
            "Implanter",
            "Interface system",
            "Transmission electron microscopy"
        ],
        "venue": "Yuanzineng Kexue Jishu/Atomic Energy Science and Technology",
        "year": 2008,
        "id": "cGzHsK1V"
    },
    "o291gSq1": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Zhengzhou Information Science and Technology Institute"
            },
            {
                "name": "Yong-Jun Zhao",
                "org": "Beijing Institute of Technology"
            },
            {
                "name": "Hao Cui",
                "org": "Zhengzhou Information Science and Technology Institute"
            }
        ],
        "title": "High resolution wideband DOA estimation based on modified MUSIC algorithm",
        "abstract": "A modified MUSIC algorithm for DOA estimation was proposed in this paper. It weighted the eigenvectors in the noise subspace which decreased the proportion of the eigenvectors of the bigger eigenvalues and increased the proportion of the eigenvectors of the smaller eigenvalues. This method adjusted the specific gravity of the eigenvectors in the spatial spectrum, and it reduced the influence of subspace expanding to MUSIC method in the nonideal instance. Then it was exerted to the wideband DOA estimating. It greatly improved the resolution of wideband DOA estimation. Simulation results verified the improvements of wideband DOA estimation by applying the modified MUSIC algorithm. \u00a9 2008 IEEE.",
        "keywords": [
            "Coherent signal-subspace method",
            "Direction-of-arrival",
            "MUSIC algorithm"
        ],
        "venue": "Proceedings of the 2008 IEEE International Conference on Information and Automation, ICIA 2008",
        "year": 2008,
        "id": "o291gSq1"
    },
    "CfisLklU": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "School of Information Science and Engineering"
            },
            {
                "name": "Zhen-Yang Wu",
                "org": "School of Information Science and Engineering"
            }
        ],
        "title": "Joint source-channel decoding algorithm based on redundancy allocation and variable estimation criterion for GSM EFR",
        "abstract": "Based on GSM EFR (Enhanced Full Rate) parameter redundancy, this paper proposes a new structure of joint source-channel decoding based on iterative channel decoder and parameter estimation. Based on the analysis of GSM EFR parameter redundancy, the paper presents the reasonable redundancy allocation strategy to arrange the two kinds of redundancy between the source decoder and channel decoder. Also, according to the characteristic of different speech coefficient, different estimation criterions are presented. Simulation results show that the algorithm of this paper improves the receiver performance significantly.",
        "keywords": [
            "Allocation strategy",
            "Iterative",
            "Joint source-channel decoding",
            "Redundancy"
        ],
        "venue": "Dianzi Yu Xinxi Xuebao/Journal of Electronics and Information Technology",
        "year": 2008,
        "id": "CfisLklU"
    },
    "9lQi63VM": {
        "authors": [
            {
                "name": "Hongjun Wang",
                "org": "Accelerator Laboratory"
            },
            {
                "name": "Jun He",
                "org": "Accelerator Laboratory"
            },
            {
                "name": "Meng Li",
                "org": "Accelerator Laboratory"
            },
            {
                "name": "Lin Zhou",
                "org": "Accelerator Laboratory"
            },
            {
                "name": "Kefei Ren",
                "org": "Accelerator Laboratory"
            },
            {
                "name": "Chuangsheng Liu",
                "org": "Accelerator Laboratory"
            },
            {
                "name": "Liping Guo",
                "org": "Accelerator Laboratory"
            },
            {
                "name": "Dejun Fu",
                "org": "Accelerator Laboratory"
            }
        ],
        "title": "Preparation and magnetic and ferroelectric properties of CdMnS",
        "abstract": "CdMnS films were prepared by and co-evaporation, and their properties were studied. The results showed CdMnS are hexagonal structure and possesses ferroelectric properties. A remnant polarization of 1.72\u03bcC/cm",
        "keywords": [
            "CdMnS",
            "Ferroelectricity",
            "Ferromagnetic",
            "Memory devices"
        ],
        "venue": "He Jishu/Nuclear Techniques",
        "year": 2009,
        "id": "9lQi63VM"
    },
    "plZ3tEw2": {
        "authors": [
            {
                "name": "Zheng Yang",
                "org": "School of Physics"
            },
            {
                "name": "Jun Xie",
                "org": "Key Laboratory of Silicate Materials Science and Engineering of Ministry of Education"
            },
            {
                "name": "Kai Sun",
                "org": "China Institute of Atomic Energy"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Physics"
            },
            {
                "name": "Zhong-Tian Yang",
                "org": "School of Physics"
            },
            {
                "name": "Jin-Shu Cheng",
                "org": "Key Laboratory of Silicate Materials Science and Engineering of Ministry of Education"
            },
            {
                "name": "Li-Ping Guo",
                "org": "China Institute of Atomic Energy"
            }
        ],
        "title": "Neutron diffraction study on glass-ceramics",
        "abstract": "Neutron diffraction and Rietveld full-pattern-fitting methods were applied to investigate the evolution of microstructure and internal stress of glass-ceramics under slow cooling and rapid cooling. Comparing to slow cooling, rapid cooling results in further elongation of the three axes for the unit cell of precipitated \u03b2-wollastonite crystal, and larger tensile stress from the residual glass phase, but smaller atomic displacive disorder. Excessive local stress results in the ermergence of micro crack in the area where stress centralizes. The intensity of amorphous peaks at high diffraction angles for the rapid cooling sample is much higher than that of the slow cooling sample, showing that the percentage of the residual glass phase in the rapid cooling sample is higher than that in the slow cooling sample. The strain value measured by neutron diffraction is very different from that of X-ray difffraction, showing that the internal stress differs significantly from the stress existing at the surface. Neutron diffraction is a practical method for determination of average residual strain in bulk glass-ceramics and for investigation of its complex microstructure where crystalline phase and glass phase coexist.",
        "keywords": [
            "Glass-ceramics",
            "Neutron diffraction",
            "Stress"
        ],
        "venue": "Yuanzineng Kexue Jishu/Atomic Energy Science and Technology",
        "year": 2009,
        "id": "plZ3tEw2"
    },
    "FE8SicCA": {
        "authors": [
            {
                "name": "Shi-Kui Wang",
                "org": "College of Physics and Electronic Information"
            },
            {
                "name": "Lin Zhou",
                "org": "College of Information Science and Engineering"
            },
            {
                "name": "Zhen-Yang Wu",
                "org": "College of Information Science and Engineering"
            },
            {
                "name": "Hong-Yan You",
                "org": "College of Information Science and Engineering"
            }
        ],
        "title": "ISF parameters concealment algorithm based on the HMM clustering means for wideband speech",
        "abstract": "There exist inevitably frame losses in the transmission of wideband speech. Due to the influence of error propagation, the quality of the received speech decays rapidly. In this paper, large hidden Markov model is adopted to model the ISF parameter in wideband speech, and the best state sequences of ISF parameters of the several speech frames before the lost frame are determined using Viterbi Algorithm. Because of the large redundancy of the HMM states, the lost ISF parameters are substituted by the weighted values between the clustering means and the real values of the ISF parameters of the nearest received frame. The speech compensated by this algorithm is compared to which by Annex I of G.722.2 specification. Simulation shows that the algorithm in this paper can result in best speech, and smaller waveform and spectrum distortion.",
        "keywords": [
            "Clustering",
            "Concealment",
            "Frame loss",
            "Hidden Markov Model (HMM)",
            "Wideband speech"
        ],
        "venue": "Dianzi Yu Xinxi Xuebao/Journal of Electronics and Information Technology",
        "year": 2009,
        "id": "FE8SicCA"
    },
    "PwmMJMXJ": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "College of Mechatronic Engineering and Automation"
            },
            {
                "name": "Yifan Dai",
                "org": "College of Mechatronic Engineering and Automation"
            },
            {
                "name": "Xuhui Xie",
                "org": "College of Mechatronic Engineering and Automation"
            },
            {
                "name": "Shengyi Li",
                "org": "College of Mechatronic Engineering and Automation"
            }
        ],
        "title": "Frequency-domain analysis of computer-controlled optical surfacing processes",
        "abstract": "Mid-high spatial frequency errors are often induced on optical surfaces polished by computer-controlled optical surfacing (CCOS) processes. In order to efficiently remove these errors, which would degrade the performances of optical systems, the ability of a CCOS process to correct the errors have been investigated based on the convolution integral model in view of the availability of material removal. To quantify the ability, some conceptions, such as figure correcting ability and material removal availability (MRA), have been proposed. The research result reveals that the MRA of the CCOS process to correct a single spatial frequency error is determined by its tool removal function (TRF), and it equals the normalized amplitude spectrum of the Fourier transform of its TRF. Finally, three sine surfaces were etched using ion beam figuring (IBF), which is a typical CCOS process. The experimental results have verified the theoretical analysis. The employed method and the conclusions of this work provide a useful mathematical basis to analyze and optimize CCOS processes. \u00a9 2009 Science in China Press and Springer-Verlag GmbH.",
        "keywords": [
            "Computer-controlled optical surfacing (CCOS)",
            "Ion beam figuring (IBF)",
            "Material removal availability (MRA)",
            "Optics machining",
            "Tool removal function (TRF)"
        ],
        "venue": "Science in China, Series E: Technological Sciences",
        "year": 2009,
        "id": "PwmMJMXJ"
    },
    "Bs30hwG7": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "College of Mechatronics Engineering and Automation"
            },
            {
                "name": "Xuhui Xie",
                "org": "College of Mechatronics Engineering and Automation"
            },
            {
                "name": "Yifan Dai",
                "org": "College of Mechatronics Engineering and Automation"
            },
            {
                "name": "Changjun Jiao",
                "org": "College of Mechatronics Engineering and Automation"
            },
            {
                "name": "Shengyi Li",
                "org": "College of Mechatronics Engineering and Automation"
            }
        ],
        "title": "Realization of velocity mode in flat optics machining using ion beam",
        "abstract": "In order to overcome the disadvantages such as more extra process time and lower machining precision in current ion beam figuring process mode, which is referred as position mode, a new process mode is proposed, which is referred as velocity mode. The method to determine the feed velocity in velocity mode is discussed in details. To demonstrate the proposed velocity mode process, a (98 flat neoceramic glass sample is figured on the ion beam figuring system KDIFS-500, which is developed by us. Its figure error is improved from initial 33.2 nm root mean square to 3.1 nm root mean square through one figuring process of 17.4 min with convergence ratio reaching 10.7. The figuring result shows that the velocity mode would save process time, improve machining precision and achieve higher convergence ratio than position mode. \u00a9 Journal of Mechanical Engineering.",
        "keywords": [
            "Computer controlled optical surfacing",
            "Dwell time",
            "Ion beam figuring",
            "Optical machining",
            "Velocity mode"
        ],
        "venue": "Jixie Gongcheng Xuebao/Journal of Mechanical Engineering",
        "year": 2009,
        "id": "Bs30hwG7"
    },
    "mtfASc8S": {
        "authors": [
            {
                "name": "Xu-Hui Xie",
                "org": "College of Mechatronics Engineering and Automation"
            },
            {
                "name": "Wen-Hua Gu",
                "org": "College of Mechatronics Engineering and Automation"
            },
            {
                "name": "Lin Zhou",
                "org": "College of Mechatronics Engineering and Automation"
            }
        ],
        "title": "Study on machining small precision optical component using thin ion beam",
        "abstract": "With the development of modern optical technology, there has been a basic requirement to control the surface error in all spatial frequency ranges for precision optics. The low spatial frequency range error of the surface can be easily and effectively eliminated by CCOS methods, but for the surface error in the middle and high spatial frequency ranges, there are few effective methods to correct them. Hence it has becomes a universal concern in modern optical manufacturing because of its serious influence on some modern precision optical systems. As is proved previously, the correcting ability of middle and high frequency error can be improved by reducing the size of the polishing lap. Based on this theory, the small ion beam figuring methode has been intruduced to solve the problem of mid and high frequency error correcting. Firstly, we studied how to gain small and steady ion beams by two methods. Then we designed a series of actual figuring experiment and computer simulation to test the effectiveness of those mothods on small scale optic surfaces. The desired results have been gained to reduce the surface error from 0.111\u03bb rms to 0.015\u03bb rms (\u03bb=632.8 nm).",
        "keywords": [
            "Ion beam figuring",
            "Middle-high frequency",
            "Polishing",
            "Surface error"
        ],
        "venue": "Guofang Keji Daxue Xuebao/Journal of National University of Defense Technology",
        "year": 2009,
        "id": "mtfASc8S"
    },
    "yBJniBMb": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "College of Mechatronics Engineering and Automation"
            },
            {
                "name": "Yi-Fan Dai",
                "org": "College of Mechatronics Engineering and Automation"
            },
            {
                "name": "Xu-Hui Xie",
                "org": "College of Mechatronics Engineering and Automation"
            },
            {
                "name": "Sheng-Yi Li",
                "org": "College of Mechatronics Engineering and Automation"
            }
        ],
        "title": "A novel path used in computer-controlled polishing process based on uniform-area-increment spiral",
        "abstract": "Archimedes spiral path, which is widely used in computer-controlled polishing process, always brings about excessively high rotational speed, and consequently excessive machining when polishing central region of the work-piece. To resolve this problem, the characteristics of a universal spiral path are studied first. It shows that the instantaneous rotational speed of the work-piece depends on the local dwell-time density and the local increase rate of the area enclosed by the spiral. Based on this, a novel spiral was proposed as a polishing path. The increase rate of the area enclosed by this new spiral is constant, and therefore, it can be referred to as uniform-area-increment spiral. This spiral path can ensure the stableness of the rotational speed of the work-piece, and reduce the rotational speed in the central region. Consequently, it can reduce the demands on motion performance to machine, and reduce the cost for machine and process. Finally, experimental results verified that Archimedes spiral path causes excessive machining in the central region due to excessive demand for rotational speed, and results in lower precision, while the uniform-area-increment spiral path avoids the excessive machining in the central region and results in higher precision.",
        "keywords": [
            "Computer-controlled polishing",
            "Ion beam figuring",
            "Polishing",
            "Spiral path"
        ],
        "venue": "Guofang Keji Daxue Xuebao/Journal of National University of Defense Technology",
        "year": 2009,
        "id": "yBJniBMb"
    },
    "CAcuAbMa": {
        "authors": [
            {
                "name": "Hongyan You",
                "org": "School of Information Science and Engineering"
            },
            {
                "name": "Shikui Wang",
                "org": "School of Information Science and Engineering"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Information Science and Engineering"
            },
            {
                "name": "Zhenyang Wu",
                "org": "School of Information Science and Engineering"
            }
        ],
        "title": "Transcoding algorithms between AMR and G.729 standards",
        "abstract": "Two transcoding algorithms between adaptive multi-rate (AMR) and G.729 standards, transcoding in index domain and transcoding in speech domain, are presented. They are to transcode between standards with the same and the different fixed codebook structure, respectively. The former translates the indexes between two standards directly, while the latter needs to search the transcoded fixed codebooks and the corresponding gains. The experimental results show that both presented transcoding algorithms can remarkably reduce the transcoding complexity. The computational complexity of transcoding in speech domain is about 55% that of Tandem transcoding, and the computational complexity of transcoding in index domain is even less than 10%. Besides, compared with Tandem transcoding, the quality of transcoded speech is improved through transcoding in index domain, and is maintained through transcoding in speech domain.",
        "keywords": [
            "Adaptive multi-rate (AMR)",
            "Fixed codebook",
            "G.729",
            "Tandem transcoding",
            "Transcoding in index domain",
            "Transcoding in speech domain"
        ],
        "venue": "Dongnan Daxue Xuebao (Ziran Kexue Ban)/Journal of Southeast University (Natural Science Edition)",
        "year": 2009,
        "id": "CAcuAbMa"
    },
    "KKoyhyXX": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Zhen-Yang Wu",
                "org": ""
            }
        ],
        "title": "Simplified iterative joint source-channel decoding algorithm",
        "abstract": "The iterative channel decoder of joint source-channel decode has the transform of log-likelihood and probability, also the multiplication and accumulation operation, which improves the computation complexity of channel decoder. In order to reduce the complexity, this paper proposes the simplified iterative channel decoding algorithm. The algorithm directly utilizes the hard decided value of channel decoder and parameter prior probability to estimate the extrinsic information for iterative channel decoder. Based on Gaussian-Markov source, simulation results show that the simplified iterative channel decoder significantly improves SNR of received parameters and reduces the computation compared with separation source channel decoder. Also, the simplified algorithm does not degrade the performance of joint source channel decoding algorithm obviously.",
        "keywords": [
            "Iterative channel decoder",
            "Joint source-channel decoding",
            "Simplified algorithm"
        ],
        "venue": "Dianzi Yu Xinxi Xuebao/Journal of Electronics and Information Technology",
        "year": 2009,
        "id": "KKoyhyXX"
    },
    "lWKYgW0F": {
        "authors": [
            {
                "name": "Wenjun Li",
                "org": ""
            },
            {
                "name": "Zhou Xu",
                "org": ""
            },
            {
                "name": "Ming Li",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Xingfan Yang",
                "org": ""
            }
        ],
        "title": "3D PIC simulation of X-band high power coupled cavity traveling wave tube",
        "abstract": "To improve the gain and stability of output microwave, an X-band high power coupled cavity traveling wave tube(CCTWT) with one RF sever and two RF lumped attenuators is studied. As an example of dot frequency microwave input, the large signal beam-wave interaction at 7.2 GHz of this X-band CCTWT is simulated using 3D PIC code. The simulated results show that this tube can produce an output power of 2.0 kW, an electron efficiency of 14.7% and a gain of 23 dB with a cavity number of 40, a beam voltage of 17 kV and a beam current of 0.8 A.",
        "keywords": [
            "3D PIC simulation",
            "High power coupled cavity traveling wave tube",
            "RF lumped attenuator",
            "RF sever",
            "X-band"
        ],
        "venue": "Qiangjiguang Yu Lizishu/High Power Laser and Particle Beams",
        "year": 2009,
        "id": "lWKYgW0F"
    },
    "abuKJPqF": {
        "authors": [
            {
                "name": "Changjun Jiao",
                "org": "School of Mechanics Engineering and Automation"
            },
            {
                "name": "Shengyi Li",
                "org": "School of Mechanics Engineering and Automation"
            },
            {
                "name": "Xuhui Xie",
                "org": "School of Mechanics Engineering and Automation"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Mechanics Engineering and Automation"
            },
            {
                "name": "Weiran Duan",
                "org": "School of Mechanics Engineering and Automation"
            }
        ],
        "title": "Bayesian principle based dwell time algorithm for ion beam figuring of low gradient mirrors",
        "abstract": "Ion beam figuring is a technology of figuring mirrors errors of high efficiency. Dwell time algorithm is one of the key problems. Based on the Bayesian principle, an iterative dwell time algorithm for planar mirrors is deduced from the computer controlled optics shaping principle. With the Gaussian extension for the data edge, the edge effect is weakened. The rapid approximate calculation of the velocity for the realization of dwell time is presented, and then the model relation between the realization error and the process parameters is deduced. By the additional smoothing factors from the error model, the realization precision for the dwell time is improved. Based on the properties of the removal function, the shaping process of low gradient mirrors can be approximated to the linear model of planar mirrors. With these discussions, the error surface controlling technology for low gradient mirrors is set up. At last, the figuring experiments on planar and spherical samples are made; the convergence rates of both can reach 9. It is concluded that the linear model is reasonable and the approximate velocity is effective. The ion beam figuring technology based on these algorithms is a deterministic process of high efficiency and can be used to correct the surface error precisely and rapidly.",
        "keywords": [
            "Bayesian principle",
            "Ion beam figuring",
            "Optical fabrication",
            "Path planning",
            "Speed mode"
        ],
        "venue": "Jixie Gongcheng Xuebao/Journal of Mechanical Engineering",
        "year": 2009,
        "id": "abuKJPqF"
    },
    "WQnztxC1": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Wenbao Han",
                "org": ""
            }
        ],
        "title": "A brief implementation analysis of SHA-1 on FPGAs, GPUs and cell processors",
        "abstract": "Recently, there has been much discussion about new advancements in processor technology that promise huge performance returns for a small investment in cryptography. Field programmable gate arrays (FPGAs), cell processors and graphics processor units (GPUs) are all the rage. We investigate the implementation and performance of SHA-1 using them, with the view of comparison their salient features. Our results showes that the implementation on FPGA could achieve the smallest performance-to-price ratio.But it cost lowest energy, had the smallest area and very stable. GUPs' performance-to-price ratio is biggest.But its power is very big around 400-600W and less stable. We can get almost of throughput of GPU using cell Processors and used less power than GPU around 135W. But its price is higher than GPUs. \u00a9 2009 IEEE.",
        "keywords": [
            ""
        ],
        "venue": "2009 International Conference on Engineering Computation, ICEC 2009",
        "year": 2009,
        "id": "WQnztxC1"
    },
    "nWhKDvgv": {
        "authors": [
            {
                "name": "Sheng Yi Li",
                "org": "School of Mechanical Engineering and Automation"
            },
            {
                "name": "Chang Jun Jiao",
                "org": "School of Mechanical Engineering and Automation"
            },
            {
                "name": "Xu Hui Xie",
                "org": "School of Mechanical Engineering and Automation"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Mechanical Engineering and Automation"
            }
        ],
        "title": "Stitching algorithm for ion beam figuring of optical mirrors",
        "abstract": "A novel stitching machining method for ion beam figuring of optical mirrors is presented in this paper. Problems that should be dealt with in the stitching process such as shaping principle, algorithm for dwell time calculation, parameter identification and compensation for positioning errors are discussed. Based on Computer Controlled Optical Surfacing (CCOS) principle, the finite field nonlinear model is deduced from the stitching shaping mechanism; with the superposition property in the model, a modified Richardson-Lucy iterative algorithm is presented to deconvolute the dwell time for the stitching process; the effect of the positioning errors and the removal rate on the machining accuracy and shape is modeled and then the identification and compensation algorithm for these parameters is proposed based on this model. With these studies, shaping theory and algorithm are constructed, and then the stitching process for ion beam figuring comes into being. Figuring experiments are made on planar samples; the process convergence ratio is 10, which is similar to that in full aperture figuring. Theoretical and experimental studies indicate that the stitching theory and algorithm in the ion beam figuring process presented in this paper are a novel method for fabrication of precision mirrors with lower cost. \u00a9 2009 Science in China Press and Springer Berlin Heidelberg.",
        "keywords": [
            "Ion beam figuring",
            "Optical fabrication",
            "Parameter identification",
            "Stitching fabrication"
        ],
        "venue": "Science in China, Series E: Technological Sciences",
        "year": 2009,
        "id": "nWhKDvgv"
    },
    "3q5Yr1uN": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Faculty of Information Engineering"
            },
            {
                "name": "Zhong Xie",
                "org": "Faculty of Information Engineering"
            },
            {
                "name": "Bo Huang",
                "org": "GIS Engineering Center"
            }
        ],
        "title": "Sharing of map symbol based on SVG",
        "abstract": "The sharing of map symbol is an obstacle to the sharing of map data. And It is a basic problem of computer mapping. Because the map symbol is always kept as an internal structure and different systems generally define different structures of map symbols, the sharing of map symbol become difficult. Researchers have tried many methods, but get fewer achievements. The paper analyzes the problems in current map symbol sharing methods and brings forward a sharing methods based on SVG. At first, analyze the basic structures of map symbols. Base on these structures; use SVG to describe the different kinds of map symbols. Then, design the sharing model of map symbol based on SVG. Finally, with the model ,realize the sharing of map symbol between two mapping systems. \u00a92009 IEEE.",
        "keywords": [
            "Map symbol library",
            "Sharing",
            "SVG",
            "TTF"
        ],
        "venue": "Proceedings - 2009 International Conference on Information Engineering and Computer Science, ICIECS 2009",
        "year": 2009,
        "id": "3q5Yr1uN"
    },
    "zz59OTU4": {
        "authors": [
            {
                "name": "Dong-Liang Wu",
                "org": "College of Mechatronics Engineering and Automation"
            },
            {
                "name": "Yi-Fan Dai",
                "org": "College of Mechatronics Engineering and Automation"
            },
            {
                "name": "Gui-Lin Wang",
                "org": "College of Mechatronics Engineering and Automation"
            },
            {
                "name": "Lin Zhou",
                "org": "College of Mechatronics Engineering and Automation"
            },
            {
                "name": "Chang-Jun Jiao",
                "org": "College of Mechatronics Engineering and Automation"
            }
        ],
        "title": "Influence of the fabrication error in IBF on the scattering loss",
        "abstract": "The removal function in ion beam figuring (IBF) exerts great influence on the fabrication residual error of optical surface, so that the performance of optical surface is changed because of the surface scattering induced by the fabrication residual error. In order to reduce the influence of the fabrication residual error on the optical performance, the IBF simulation procedure based on the computer controlled optical surfacing (CCOS) technique was used in surfacing the optical mirrors, and the influence of the removal function width on the ratio of scattering loss (RSL) was analyzed. It was shown that the influence of the fabrication residual error on the RSL declines with decrease of the removal function width. Thus the removal function width can be chosen reasonably according to the influence of the fabrication residual error on the RSL and the requirement of RSL index, and the processing technique can be optimized under the condition of satisfying the surface accuracy requirement of the optical mirrors.",
        "keywords": [
            "CCOS",
            "Fabrication residual error",
            "Ion beam figuring",
            "Ratio of scattering loss",
            "Removal function"
        ],
        "venue": "Guofang Keji Daxue Xuebao/Journal of National University of Defense Technology",
        "year": 2009,
        "id": "zz59OTU4"
    },
    "4A8FvA3P": {
        "authors": [
            {
                "name": "Xuhui Xie",
                "org": "School of Mechanical Engineering and Automation"
            },
            {
                "name": "Changjun Jiao",
                "org": "School of Mechanical Engineering and Automation"
            },
            {
                "name": "Shengyi Li",
                "org": "School of Mechanical Engineering and Automation"
            },
            {
                "name": "Weiran Duan",
                "org": "School of Mechanical Engineering and Automation"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Mechanical Engineering and Automation"
            }
        ],
        "title": "Ion beam figuring method for optical mirrors with spiral scan mode",
        "abstract": "The ion beam figuring method for optical mirrors with spiral scan mode is discussed. With the near-Gaussian property of the removal function, the figuring process can be simplified to a linear one and described by conventional computer controlled optics shaping (CCOS) principle. The modified Richard-Lucy iterative algorithm based on the Bayesian principle is adopted for the solution of dwell time. On the basis of analysis of the continuous velocity of dwell time, the criteria for determining the spiral path parameters are given. With these methods, the ion beam figuring technology with spiral scan mode is established. The figuring experiments on planar and aspheric samples are made, the final surface errors are both below 1/100\u03bb. The experimental results show that spiral figuring is a deterministic method of high efficiency for optical mirrors, and can be used as the final figuring process, moreover the processing cost can be reduced. \u00a9 2009 Journal of Mechanical Engineering.",
        "keywords": [
            "Ion beam figuring",
            "Optical fabrication",
            "Richard-Lucy iterative algorithm",
            "Spiral scan mode"
        ],
        "venue": "Jixie Gongcheng Xuebao/Journal of Mechanical Engineering",
        "year": 2009,
        "id": "4A8FvA3P"
    },
    "yvd4HzUC": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Lin Wan",
                "org": ""
            }
        ],
        "title": "GIS spatial data integration based on grid computing",
        "abstract": "Multi-source heterogeneous spatial data has been the obstacle of the spatial information sharing.So,in the network environment, how to integrate multi-sources heterogeneous spatial data has become a hot and difficult problem of GIS. This article aimed to solve the problem by grid computing technology,and put forward a model of multi-sources heterogeneous spatial data integration based on it.Use Globus Toolkit and OGSA-DAI to establish a heterogeneous data integration platform.Based on the platform,various heterogeneous data sources can be connected seamlessly.Each data source node can be registered on it for data sharing. The platform can also harmonize and manage all data source nodes,and provide users with a unified and transparent access interface. With the existing grid middleware tool Globus Toolkit and OGSA-DAI,grid development tools can be packaged, thereby shielding the complexity of grid theory and the tools.Integrate a number of distribution, independent heterogeneous data sources into a specific environment,realize the the unification inquirment on these multi-database systems, shielding the differences of database structures, operating environments, network distribution and concrete Physical location to ensure the independence of each database node and data security. \u00a9 2010 IEEE.",
        "keywords": [
            "GIS",
            "Gobus toolkit",
            "Grid computing",
            "OGSA",
            "Spatial data integration"
        ],
        "venue": "ICCMS 2010 - 2010 International Conference on Computer Modeling and Simulation",
        "year": 2010,
        "id": "yvd4HzUC"
    },
    "doNdADgj": {
        "authors": [
            {
                "name": "Derong Deng",
                "org": "Institute of Applied Electronics"
            },
            {
                "name": "Lin Zhou",
                "org": "Institute of Applied Electronics"
            },
            {
                "name": "Lijun Shan",
                "org": "Institute of Applied Electronics"
            }
        ],
        "title": "Periodic permanent magnetic focusing system for X-band coupled cavity traveling wave tube",
        "abstract": "Designed through research of electron beam transmission characteristic in different coupled cavity structures, long periodic permanent magnetic focusing system solves problems of factors influencing electron trajectories such as transverse magnetic field, open magnetic ring and magnetic field in transition region. 3D program simulation of electron optics system for X-band coupled cavity traveling wave tube shows 100% transfer efficiency of electron beam and 9% ripple of electron beam, which accords with requirements of coupled cavity traveling wave tube experiment.",
        "keywords": [
            "Coupled cavity traveling wave tube",
            "Electron beam transmission",
            "Periodic permanent magnetic",
            "Transverse magnetic field"
        ],
        "venue": "Qiangjiguang Yu Lizishu/High Power Laser and Particle Beams",
        "year": 2010,
        "id": "doNdADgj"
    },
    "vWUl4bia": {
        "authors": [
            {
                "name": "Jianmin Qi",
                "org": "Institute of Nuclear Physics and Chemistry"
            },
            {
                "name": "Shilun Jiang",
                "org": "Institute of Nuclear Physics and Chemistry"
            },
            {
                "name": "Lin Zhou",
                "org": "Institute of Nuclear Physics and Chemistry"
            },
            {
                "name": "Taiping Peng",
                "org": "Institute of Nuclear Physics and Chemistry"
            }
        ],
        "title": "Design of magnetic analysis system for magnetic proton recoil spectrometer",
        "abstract": "Magnetic proton recoil (MPR) spectrometer is a novel diagnostic instrument with high performance for measurements of the neutron spectra from inertial confinement fusion (ICF) experiments and high power fusion devices. The design of the magnetic analysis system, which is a key part of the compact MPR-type spectrometer, has been completed through two-dimensional beam transport simulations and three-dimensional particle transport simulations. The analysis of the system's parameters and performances was performed, as well as system designs based on preferential principles of energy resolution, detection efficiency, and count rate, respectively. The results indicate that the magnetic analysis system can achieve a detection efficiency of 10\n                        ",
        "keywords": [
            "Energy spectrum",
            "Fusion neutron",
            "Magnetic analysis",
            "Magnetic proton recoil",
            "Simulation"
        ],
        "venue": "Qiangjiguang Yu Lizishu/High Power Laser and Particle Beams",
        "year": 2010,
        "id": "vWUl4bia"
    },
    "BdKOY5h9": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Information Engineering Institute"
            },
            {
                "name": "Wen-Bao Han",
                "org": "Information Engineering Institute"
            },
            {
                "name": "Wei-Hua Zhu",
                "org": "Information Engineering Institute"
            },
            {
                "name": "Zheng Wang",
                "org": "Information Engineering Institute"
            }
        ],
        "title": "Improvement and efficient implementation of differential attack algorithm to MDx on GPGPU",
        "abstract": "Hash functions are widely used in business, military field etc. Among them, MD-family Hash functions are the most extensively utilized hash functions. Therefore, the attack to MD-family hash functions has important meaning in theory and in practical application. Since professor Wang proposed differential attack algorithm and succeeded to break MD5, MD4, etc MD-family algorithms, this algorithm has been paid more and more attention. This paper takes the tunnel differential attack algorithm to MD5 as example, improves the tunnel differential attack algorithm to MD5 proposed by Klima and analyzes the feasibility and technology request of differential attack algorithm's implementation on GPGPU. Its CUDA program run on the GeForce 9800 GX2 platform and can find a pair of MD5 collision in just 1.35 seconds average. Through comparing the software implementation on PC Core 2 Quad Q9000 (2.0 GHz), we can get nearly 11.5 times more cost-efficient by the implementation on GeForce 9800 GX2.",
        "keywords": [
            "CUDA",
            "Differential attack",
            "GPGPU",
            "Hash functions",
            "MD5",
            "Mersenne Twister",
            "Multi-message modification method",
            "Tunnel technique"
        ],
        "venue": "Jisuanji Xuebao/Chinese Journal of Computers",
        "year": 2010,
        "id": "BdKOY5h9"
    },
    "bQ7Hhlhz": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Dept. of Mechatronic Engineering"
            },
            {
                "name": "Yifan Dai",
                "org": "Dept. of Mechatronic Engineering"
            },
            {
                "name": "Xuhui Xie",
                "org": "Dept. of Mechatronic Engineering"
            },
            {
                "name": "Shengyi Li",
                "org": "Dept. of Mechatronic Engineering"
            }
        ],
        "title": "Optimum removal in ion-beam figuring",
        "abstract": "In an ion-beam figuring (IBF) process, the desired material removal, which is specified to the contour algorithm to calculate dwell time, decides the calculated process time and the resulted residual surface figure error. Usually, an IBF process with more removal consumes a longer process time, although the resulted residual error is smaller, whereas an IBF process with less removal needs only a shorter process time, but the resulted residual error is greater. Therefore, in order to balance the process time and the residual error, an optimum removal should be determined. In this study, the characteristic relationship between the process time and the residual error on different specified removals is investigated first. The investigation shows that for smaller removals, the residual error decreases rapidly while the process time increases slowly, and for larger removals, the process time increases rapidly without much decrease in residual error. This characteristic makes the figure-prediction curve (process times vs. rediual errors (RMS)) often in the shape of the letter \"L\". Therefore, the optimum removal can be determined at the corner of the curve. Finaly, experiments are performed to verify the proposed method. \u00a9 2010 Elsevier Inc. All rights reserved.",
        "keywords": [
            "Figure-prediction curve",
            "Ion-beam figuring",
            "Material removal",
            "Polishing",
            "Process time",
            "Residual error"
        ],
        "venue": "Precision Engineering",
        "year": 2010,
        "id": "bQ7Hhlhz"
    },
    "fxjdMoXX": {
        "authors": [
            {
                "name": "Chuansheng Liu",
                "org": "Department of Physics and Acoustic and Photonic Materials and Devices"
            },
            {
                "name": "Hongjun Wang",
                "org": "Department of Physics and Acoustic and Photonic Materials and Devices"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Physics and Acoustic and Photonic Materials and Devices"
            },
            {
                "name": "Rui Zhang",
                "org": "Department of Physics and Acoustic and Photonic Materials and Devices"
            },
            {
                "name": "Canxin Tian",
                "org": "Department of Physics and Acoustic and Photonic Materials and Devices"
            },
            {
                "name": "Ming Li",
                "org": "Department of Physics and Acoustic and Photonic Materials and Devices"
            },
            {
                "name": "Dejun Fu",
                "org": "Department of Physics and Acoustic and Photonic Materials and Devices"
            }
        ],
        "title": "Structure and mechanical properties of CrN thick films deposited by high-rate medium-frequency magnetron sputtering",
        "abstract": "A home-made electron source assisted medium-frequency (MF) magnetron sputtering system was used to deposit thick CrN films on silicon and tungsten carbide substrates at various nitrogen flow rates with a fixed total pressure (0.3 Pa) and MF power (11.2 kW). Result from scanning electron microscopy showed that the deposited CrN films have clear columnar structure, and X-ray diffraction revealed a preferred orientation of CrN (200) for samples prepared at a rate of N",
        "keywords": [
            "CrN",
            "Electron source",
            "Hardness",
            "Medium frequency magnetron sputtering",
            "Structure"
        ],
        "venue": "Plasma Science and Technology",
        "year": 2010,
        "id": "fxjdMoXX"
    },
    "JslAu0hW": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "School of Automation"
            },
            {
                "name": "Quan Pan",
                "org": "School of Automation"
            },
            {
                "name": "Yan Liang",
                "org": "School of Automation"
            }
        ],
        "title": "Application of improved SA-PSO in the system error registration",
        "abstract": "System error is change in some fusion system. In order to resolve the problem of system error registration, this paper combine improved Particle Swarm Optimization (PSO) with Simulated Annealing (SA). This method integrates the capacity of fast optimization seeking in improved PSO with the characteristic of probabilistic leap in S A, which not only solves the defect that PSO easily plunges into local optimum, but also ensures population variety and avoids population degradation. The simulations show that compared with PSO and GA, improved SA-PSO has better precision in system error registration.",
        "keywords": [
            "Error registration",
            "Particle swarm optimization (PSO)",
            "Simulated annealing (SA)",
            "System error"
        ],
        "venue": "Guangdian Gongcheng/Opto-Electronic Engineering",
        "year": 2010,
        "id": "JslAu0hW"
    },
    "qwEUK6zu": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Institute of Nuclear Physics and Chemistry"
            },
            {
                "name": "Shilun Jiang",
                "org": "Institute of Nuclear Physics and Chemistry"
            },
            {
                "name": "Jianmin Qi",
                "org": "Institute of Nuclear Physics and Chemistry"
            }
        ],
        "title": "A magnetic analyzer for magnetic proton recoil spectrometer and the spectrometer performance",
        "abstract": "A compact magnetic analyzer for magnetic proton recoil spectrometer has been developed at CAEP. Nd-Fe-B permanent dipole is used as the analyzing magnet, with a focal plane detector of CR39. Performance of the analyzer was studied with the actual magnetic field distribution and charged particle transport code. Experiments were performed with a \n                        ",
        "keywords": [
            "Magnetic analyzer",
            "Magnetic proton recoil (MPR)",
            "Monte Carlo",
            "Neutron spectrum"
        ],
        "venue": "He Jishu/Nuclear Techniques",
        "year": 2010,
        "id": "qwEUK6zu"
    },
    "NpAZWQw2": {
        "authors": [
            {
                "name": "Yong L\u00fc",
                "org": "School of Information Science and Engineering"
            },
            {
                "name": "Haiyang Wu",
                "org": "School of Information Science and Engineering"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Information Science and Engineering"
            },
            {
                "name": "Zhenyang Wu",
                "org": "School of Information Science and Engineering"
            }
        ],
        "title": "Multi-environment model adaptation based on vector Taylor series for robust speech recognition",
        "abstract": "In this paper, we propose a multi-environment model adaptation method based on vector Taylor series (VTS) for robust speech recognition. In the training phase, the clean speech is contaminated with noise at different signal-to-noise ratio (SNR) levels to produce several types of noisy training speech and each type is used to obtain a noisy hidden Markov model (HMM) set. In the recognition phase, the HMM set which best matches the testing environment is selected, and further adjusted to reduce the environmental mismatch by the VTS-based model adaptation method. In the proposed method, the VTS approximation based on noisy training speech is given and the testing noise parameters are estimated from the noisy testing speech using the expectation-maximization (EM) algorithm. The experimental results indicate that the proposed multi-environment model adaptation method can significantly improve the performance of speech recognizers and outperforms the traditional model adaptation method and the linear regression-based multi-environment method. \u00a9 2010 Elsevier Ltd. All rights reserved.",
        "keywords": [
            "Model adaptation",
            "Multi-environment model",
            "Speech recognition",
            "Vector Taylor series"
        ],
        "venue": "Pattern Recognition",
        "year": 2010,
        "id": "NpAZWQw2"
    },
    "E1yIVxqG": {
        "authors": [
            {
                "name": "Hongjun Wang",
                "org": "Quantum Functional Semiconductor Research Center"
            },
            {
                "name": "Changwei Zou",
                "org": "Department of Physics"
            },
            {
                "name": "Canxin Tian",
                "org": "Department of Physics"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Physics"
            },
            {
                "name": "Ming Li",
                "org": "Department of Physics"
            },
            {
                "name": "Dejun Fu",
                "org": "Department of Physics"
            },
            {
                "name": "Taewon Kang",
                "org": "Quantum Functional Semiconductor Research Center"
            }
        ],
        "title": "Formation of GaN nanostructures with various morphologies by photo-assisted electroless chemical etching",
        "abstract": "Interaction of GaN crystal faces with chemicals is crucial to understand why various nanostructures are formed during the etching process. We have prepared GaN nanostructures by a photo-assisted electroless chemical etching method in solutions containing KOH and K\n                        ",
        "keywords": [
            "Nanomaterials",
            "Semiconductors",
            "Surfaces"
        ],
        "venue": "Materials Letters",
        "year": 2010,
        "id": "E1yIVxqG"
    },
    "FfwpzUYA": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Info. Eng. Insti."
            },
            {
                "name": "Zheng Wang",
                "org": "Info. Eng. Insti."
            },
            {
                "name": "Wen-Bao Han",
                "org": "Info. Eng. Insti."
            }
        ],
        "title": "The automatic algorithm to construct difference and differential path in MD5",
        "abstract": "For Finding good difference, differential path and sufficient conditions, the theory of MD5 and differential attack algorithm were analyzed, four probabilities of circle shifting difference were proved, and the automatic algorithm to construct difference and differential path in MD5 were proposed. By combining the construction of difference with differential path and modifying the length of searching step, the successful probability of construction was promoted. Experiments showed that this differential path's HW is 50, and 272 sufficient conditions is needed.",
        "keywords": [
            "Differential attack",
            "Hash functions",
            "MD5",
            "Multi-message modification method",
            "Tunnel technique"
        ],
        "venue": "Sichuan Daxue Xuebao (Gongcheng Kexue Ban)/Journal of Sichuan University (Engineering Science Edition)",
        "year": 2010,
        "id": "FfwpzUYA"
    },
    "SR7POp91": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "School of Design"
            },
            {
                "name": "Weimin Guo",
                "org": "School of Design"
            },
            {
                "name": "Jing Luo",
                "org": "School of Design"
            }
        ],
        "title": "SketchUp aided dynamic landscape design - A case of Helv Fuan shopping street landscape design of Hudai",
        "abstract": "Along with the rapid development of computer technology, computer-aided design software is widely applied to various industries. And there is no exception for landscape design. This essay is about the relationship between computer-aided design and dynamic landscape design, and discusses the characteristics, methods and steps of using computer-aided design theory for dynamic landscape design. Through a detailed explanation of a real case, we introduced the important role computer-aided dynamic landscape design has played in the idea-developing process. We also come up with the corresponding solutions and suggestions, and carry out a fundamental discussion on its application outlook. \u00a9 2010 IEEE.",
        "keywords": [
            "Computer-aided design",
            "Dynamic landscape design",
            "Sketch up"
        ],
        "venue": "2010 IEEE 11th International Conference on Computer-Aided Industrial Design and Conceptual Design, CAID and CD'2010",
        "year": 2010,
        "id": "SR7POp91"
    },
    "betejvSy": {
        "authors": [
            {
                "name": "Jianlin Zhang",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            }
        ],
        "title": "Research and design on network topology management system of EJB clustering",
        "abstract": "This paper analyzes some approaches to manage the network topology of EJB clustering, and presents a Network Topology Management System that based on shared global JNDI, including overall design for this system and detailed design for some key technologies. The Management of network topology is a submodule of cluster service, and it makes the cluster system have two important features: flexible scalability and high availability. Besides, this paper not only emphasizes on portability and extensibility of the system but also completes the collect of load information in the design procedure, so it is easy to expand this system and then integrate the system to J2EE application server. \u00a92010 IEEE.",
        "keywords": [
            "EJB clustering",
            "Global JNDI",
            "Load balance",
            "Network topology"
        ],
        "venue": "2010 International Conference on Computational Intelligence and Software Engineering, CiSE 2010",
        "year": 2010,
        "id": "betejvSy"
    },
    "LRq1Ljqw": {
        "authors": [
            {
                "name": "Chuansheng Liu",
                "org": ""
            },
            {
                "name": "Ming Li",
                "org": ""
            },
            {
                "name": "Jun He",
                "org": ""
            },
            {
                "name": "Zheng Yang",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Zesong Wang",
                "org": ""
            },
            {
                "name": "Liping Guo",
                "org": ""
            },
            {
                "name": "Changzhong Jiang",
                "org": ""
            },
            {
                "name": "Shibo Yang",
                "org": ""
            },
            {
                "name": "Jiarui Liu",
                "org": ""
            },
            {
                "name": "J.C. Lee",
                "org": ""
            },
            {
                "name": "Dejun Fu",
                "org": ""
            },
            {
                "name": "Xiangjun Fan",
                "org": ""
            }
        ],
        "title": "Accelerator-TEM interface facility and application",
        "abstract": "An accelerator-TEM interface facility has been established at Wuhan University in 2008. The system consists of an H800 TEM linked to a 200 kV ion implanter and a 2 \u00d7 1.7 MV tandem accelerator. Nitrogen ions at 115 keV were successfully transported from the implanter into the TEM chamber through the interface system, and the ion currents measured at the entrance of the TEM column were between 20 and 180 nA. Structural evolution caused by ion irradiation in Si, GaAs, nanocrystal Ag was observed in situ. The in situ observation showed that the critical implantation dose for amorphization of Si is 10",
        "keywords": [
            "Accelerator",
            "Electron microscopy",
            "Interface system",
            "Ion implanter",
            "Ion transport line"
        ],
        "venue": "He Jishu/Nuclear Techniques",
        "year": 2010,
        "id": "LRq1Ljqw"
    },
    "nDXMLFVd": {
        "authors": [
            {
                "name": "Jian-Min Qi",
                "org": "Institute of Nuclear Physics and Chemistry"
            },
            {
                "name": "Lin Zhou",
                "org": "Institute of Nuclear Physics and Chemistry"
            },
            {
                "name": "Shi-Lun Jiang",
                "org": "Institute of Nuclear Physics and Chemistry"
            },
            {
                "name": "Tai-Ping Peng",
                "org": "Institute of Nuclear Physics and Chemistry"
            }
        ],
        "title": "Characteristics of the magnetic analysis system for a compact MPR-type spectrometer",
        "abstract": "The magnetic proton recoil (MPR) spectrometer is a novel diagnostic instrument with high performance for measurements of neutron spectra in inertial confinement fusion (ICF) experiments and high power fusion devices. A compact MPR-type spectrometer dedicated to the research of pulsed deuterium-tritium (DT) neutron spectroscopy of special experimental conditions is currently under design. Analyses of the main parameters and performance of the magnetic analysis system through 3-D particle transport calculations and MonteCarlo simulations and calibration of the system performance as a test using CR-39 solid track detector and \u03b1. particle from \n                        ",
        "keywords": [
            "Fusion neutron",
            "Magnetic analysis",
            "Magnetic proton recoil (MPR)",
            "Spectrometer"
        ],
        "venue": "Chinese Physics C",
        "year": 2010,
        "id": "nDXMLFVd"
    },
    "SAzK5yP9": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Automotive Safety and Energy"
            },
            {
                "name": "Si-Fa Zheng",
                "org": "State Key Laboratory of Automotive Safety and Energy"
            },
            {
                "name": "Xiao-Min Lian",
                "org": "State Key Laboratory of Automotive Safety and Energy"
            }
        ],
        "title": "Modeling and research on torsional vibration of transmission system under speeding-up condition",
        "abstract": "The torsional vibration of the transmission system is one of the most important resources of vehicle NVH (noise, vibration and harshness) problem. As a complex system, the transmission system involves non-linear gear meshing, as well as the elastic deformation of the driveline and half shaft. To solve the problem, this paper firstly analyses the non-linear gear meshing based on dynamics of gear system and the Hertz elastic theory. Then a simulation model has been built with non-linear gears meshing of a transmission, two elastic drivelines, a differential, two half shafts and two tires. The dynamic characteristics have been investigated with the model. At the end the torsional vibration of the transmission system under speeding-up condition and comparisons with a real vehicle results are studied.",
        "keywords": [
            "Flexible body",
            "Hertz elastic theory",
            "Multi-body dynamics",
            "Torsional vibration",
            "Transmission system"
        ],
        "venue": "Zhendong Gongcheng Xuebao/Journal of Vibration Engineering",
        "year": 2010,
        "id": "SAzK5yP9"
    },
    "eITkEIfg": {
        "authors": [
            {
                "name": "Yifan Dai",
                "org": "College of Mechatronic Engineering and Automation"
            },
            {
                "name": "Wenlin Liao",
                "org": "College of Mechatronic Engineering and Automation"
            },
            {
                "name": "Shanyong Chen",
                "org": "College of Mechatronic Engineering and Automation"
            },
            {
                "name": "Lin Zhou",
                "org": "College of Mechatronic Engineering and Automation"
            },
            {
                "name": "Xuhui Xie",
                "org": "College of Mechatronic Engineering and Automation"
            }
        ],
        "title": "Theoretical analysis and experimental study of material removal characteristics in ion beam figuring process",
        "abstract": "Based on the Sigmund sputtering theory, the material removal characteristics in ion beam figuring process are analyzed. The analysis shows that the footprint of beam removal function and the removal rate vary with different incidence angles, which is validated by experiments on small fused silica samples. These material removal characteristics are valuable in ion beam figuring process, which could be applied to machining spherical surfaces and aspherical surfaces with simple method. \u00a9 2010 Copyright SPIE - The International Society for Optical Engineering.",
        "keywords": [
            "Incidence Angles",
            "Ion Beam Figuring (IBF)",
            "Material Removal Characteristics",
            "Spherical Surface"
        ],
        "venue": "Proceedings of SPIE - The International Society for Optical Engineering",
        "year": 2010,
        "id": "eITkEIfg"
    },
    "rSCi7ykj": {
        "authors": [
            {
                "name": "Jing Luo",
                "org": "School of Design"
            },
            {
                "name": "Weimin Guo",
                "org": "School of Design"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Design"
            }
        ],
        "title": "The application of CAAD technology in regional architectural renewal",
        "abstract": "With the expatiation of the history and current situation of the application of computer-aided architectural design technology, the paper shows that the previous application mode of \"computer-aided design drawing\" has been dramatically shifted to the mode of \"computer-aided design thinking\" during the past decades. Taking the example of the regional hotel design in Qingming bridge historical district in Wuxi, China, the paper discusses the methods and process of applying computer-aided architectural design technology in regional architectural renewal from the cross perspectives of computer graphics, architecture and art design. \u00a9 2010 IEEE.",
        "keywords": [
            "Computer-aided architectural design",
            "Regional architecture",
            "Renewal"
        ],
        "venue": "ICEIT 2010 - 2010 International Conference on Educational and Information Technology, Proceedings",
        "year": 2010,
        "id": "rSCi7ykj"
    },
    "7AM5ZuRX": {
        "authors": [
            {
                "name": "Yifan Dai",
                "org": "National University of Defense Technology"
            },
            {
                "name": "Wenlin Liao",
                "org": "National University of Defense Technology"
            },
            {
                "name": "Lin Zhou",
                "org": "National University of Defense Technology"
            },
            {
                "name": "Shanyong Chen",
                "org": "National University of Defense Technology"
            },
            {
                "name": "Xuhui Xie",
                "org": "National University of Defense Technology"
            }
        ],
        "title": "Ion beam figuring of high-slope surfaces based on figure error compensation algorithm",
        "abstract": "In a deterministic figuring process, it is critical to guarantee high stability of the removal function as well as the accuracy of the dwell time solution, which directly influence the convergence of the figuring process. Hence, when figuring steep optics, the ion beam is required to keep a perpendicular incidence, and a five-axis figuring machine is typically utilized. In this paper, however, a method for high-precision figuring of high-slope optics is proposed with a linear three-axis machine, allowing for inclined beam incidence. First, the changing rule of the removal function and the normal removal rate with the incidence angle is analyzed according to the removal characteristics of ion beam figuring (IBF). Then, we propose to reduce the influence of varying removal function and projection distortion on the dwell time solution by means of figure error compensation. Consequently, the incident ion beam is allowed to keep parallel to the optical axis. Simulations and experiments are given to verify the removal analysis. Finally, a figuring experiment is conducted on a linear three-axis IBF machine, which proves the validity of the method for high-slope surfaces. It takes two iterations and about 9 min to successfully figure a fused silica sample, whose aperture is 21.3 mm and radius of curvature is 16 mm. The root-mean-square figure error of the convex surface is reduced from 13.13 to 5.86 nm. \u00a9 2010 Optical Society of America.",
        "keywords": [
            ""
        ],
        "venue": "Applied Optics",
        "year": 2010,
        "id": "7AM5ZuRX"
    },
    "8R6oRseM": {
        "authors": [
            {
                "name": "Long Guo",
                "org": "Institute of Information Engineering"
            },
            {
                "name": "Xi-Jian Ping",
                "org": "Institute of Information Engineering"
            },
            {
                "name": "Lin Zhou",
                "org": "Institute of Information Engineering"
            },
            {
                "name": "Li Tong",
                "org": "Institute of Information Engineering"
            }
        ],
        "title": "Identification of scripts in document images using basic image features",
        "abstract": "In this paper, a novel script identification method based on basic image features (BIF) is proposed to resolve the conflict between the speed of feature extraction and accuracy of identification. According to the concept of structural approach to texture analysis, texture basic units are divided into seven types. Support vector machine (SVM) is used to train and classify the features, which describe the structure and distribution of texture basic units, to identify scripts in different languages. Experiments have been performed upon degraded document images including ten languages including Chinese, Russian, English, Japanese, Korean, Arabic, etc. Experimental results confirm that the proposed method can identify scripts accurately and efficiently. It is robust against image degradation.",
        "keywords": [
            "Basic image feature (BIF)",
            "Document image",
            "Script identification",
            "Support vector machine"
        ],
        "venue": "Yingyong Kexue Xuebao/Journal of Applied Sciences",
        "year": 2011,
        "id": "8R6oRseM"
    },
    "7BVF4lfm": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Automotive Safety and Energy"
            },
            {
                "name": "Si-Fa Zheng",
                "org": "State Key Laboratory of Automotive Safety and Energy"
            },
            {
                "name": "Bin-Xing Wang",
                "org": "State Key Laboratory of Automotive Safety and Energy"
            },
            {
                "name": "Xiao-Min Lian",
                "org": "State Key Laboratory of Automotive Safety and Energy"
            },
            {
                "name": "Ke-Qiang Li",
                "org": "State Key Laboratory of Automotive Safety and Energy"
            }
        ],
        "title": "Coherence analysis method for dynamic force identification",
        "abstract": "Dynamic force identification from structural response is necessary when direct measurement is impossible. Frequency-domain force identification is widely researched. This approach is to determine the frequency response function (FRF) matrix, measure the responses on structure, and calculate the dynamic forces. This approach has been proven to be effective. However, the accuracy of this approach is often influenced by the inversion of an ill-conditioned FRF matrix especially at the frequency of structural resonances. To solve the problem, firstly this paper analyses how the locations of responses influence the illness of FRF matrix and the accuracy of force identification. Then a new method based on FRF coherence analysis is proposed to optimize spatial distribution of response locations. Compared with two other methods in reference this approach is more effective but involve less computational efforts. The error reduction in force determination is found to be significant in numerical simulations on a simple plate and in a cab experiments.",
        "keywords": [
            "Coherence analysis method",
            "Coherence factor",
            "Force identification",
            "Frequency-domain",
            "Ill-posed problem"
        ],
        "venue": "Zhendong Gongcheng Xuebao/Journal of Vibration Engineering",
        "year": 2011,
        "id": "7BVF4lfm"
    },
    "2UzCDXZO": {
        "authors": [
            {
                "name": "Wen-Lin Liao",
                "org": "College of Mechatronics Engineering and Automation"
            },
            {
                "name": "Yi-Fan Dai",
                "org": "College of Mechatronics Engineering and Automation"
            },
            {
                "name": "Lin Zhou",
                "org": "College of Mechatronics Engineering and Automation"
            },
            {
                "name": "Jian-Min Wang",
                "org": "College of Mechatronics Engineering and Automation"
            },
            {
                "name": "Zheng Yuan",
                "org": "College of Mechatronics Engineering and Automation"
            },
            {
                "name": "Xu-Hui Xie",
                "org": "College of Mechatronics Engineering and Automation"
            }
        ],
        "title": "Ion beam figuring for rectangular off-axis aspheric mirrors",
        "abstract": "A simple method of ion beam figuring was successfully employed for processing rectangular off-axis aspheric mirror. Based on the material removal mechanism, the normal removal characteristic was analyzed. Beam diameter, peak removal rate and volume removal rate are the three factors to evaluate the robustness of removal function with respect to little disturbance of incidence angle. According to the results of analyses and experiments, the method of processing rectangular off-axis aspheric mirror by ion beam figuring was appropriately simplified. To validate the feasibility of this method, an off-axis aspheric ellipsoidal mirror was processed in our IBF system. With three iterations of 200 minutes, the surface error was reduced from 0.294\u03bb RMS to 0.05\u03bb RMS and the total convergence ratio was 10. The experimental results indicate that IBF has inimitable material removal characteristics, can effectively improve surface precision and realize the rapid processing of ultra-precision rectangular off-axis aspheric mirror.",
        "keywords": [
            "Ion beam figuring",
            "Material removal characteristics",
            "Off-axis asphere mirror",
            "Removal function"
        ],
        "venue": "Guofang Keji Daxue Xuebao/Journal of National University of Defense Technology",
        "year": 2011,
        "id": "2UzCDXZO"
    },
    "9e0Qq6k7": {
        "authors": [
            {
                "name": "Fan Wang",
                "org": "School of Electronic Information"
            },
            {
                "name": "Huotao Gao",
                "org": "School of Electronic Information"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Electronic Information"
            }
        ],
        "title": "All-digital high frequency radar receiver with multi-channels using FPGA",
        "abstract": "On the concept of software radio, a design of multi-channel all-digital high frequency radar receiver was presented, which carried out the system controls and sample data transmission by the USB2.0 interface. Synchronization control, digital quadrature demodulation and digital down converter were implemented based on Altera CycloneII family field programmable gate array (FPGA). Compared with the traditional analog receiver and intermediate frequency receiver, it has an easy hardware structure, convenient for parameter configuration. The system closed-loop test shows the correctness and rationality of the design, meeting the demand of engineering applications.",
        "keywords": [
            "All-digital receiver",
            "Digital down converter",
            "Field programmable gate array",
            "High frequency radar",
            "Orthogonal transformation",
            "Radar receiver"
        ],
        "venue": "Huazhong Keji Daxue Xuebao (Ziran Kexue Ban)/Journal of Huazhong University of Science and Technology (Natural Science Edition)",
        "year": 2011,
        "id": "9e0Qq6k7"
    },
    "yQXf8xNg": {
        "authors": [
            {
                "name": "Jian-Min Qi",
                "org": "Institute of Nuclear Physics and Chemistry"
            },
            {
                "name": "Lin Zhou",
                "org": "Institute of Nuclear Physics and Chemistry"
            },
            {
                "name": "Shi-Lun Jiang",
                "org": "Institute of Nuclear Physics and Chemistry"
            }
        ],
        "title": "Design and performance analysis of a compact magnetic proton recoil spectrometer for DT neutrons",
        "abstract": "A magnetic proton recoil (MPR) spectrometer is a novel instrument with superior performance, including high energy resolution, high count rate and good signal-to-noise ratio (SNR) for measurements of neutron spectra from inertial confinement fusion (ICF) experiments and high power Tokomaks. In this work, the design of a compact MPR spectrometer (cMPR) was evaluated for deuteron-tritium (DT) neutron spectroscopy. The characteristics of the spectrometer were analyzed using 2-D beam transport simulations, 3-D particle transport calculations and Monte-Carlo simulations. Based on the theoretical results, an instrument design that satisfies special experimental requirements is proposed. The energy resolution and efficiency of the spectrometer are also evaluated. The results indicate that the proposed cMPR spectrometer would achieve a detection efficiency and energy resolution of approximately 10\n                        ",
        "keywords": [
            "compact",
            "DT neutron",
            "Magnetic proton recoil (MPR)",
            "neutron spectrometer"
        ],
        "venue": "Chinese Physics C",
        "year": 2011,
        "id": "yQXf8xNg"
    },
    "wZKoazye": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Institute of Information Engineering"
            },
            {
                "name": "Xi-Jian Ping",
                "org": "Institute of Information Engineering"
            },
            {
                "name": "Li Tong",
                "org": "Institute of Information Engineering"
            }
        ],
        "title": "Improved method of adaptive distance preserving level set evolution",
        "abstract": "In this paper, an improved method of adaptive distance preserving level set evolution is proposed. A weighting coefficient depending on information in the image and a stop function are defined. The evolution curve is no longer sensitive to the position of the initial curve, which can be anywhere in the image. The curve of zero level set can detect object boundaries when it is in a region with pixels having the same gray value. The method enhances capability of detecting boundary concavities. Experiments on images with different object boundaries show that the proposed method can detect the object contour effectively and has strong anti-noise ability.",
        "keywords": [
            "Distance preserving level set method",
            "Geometric active contour mode",
            "Image segmentation",
            "Partial differential equation"
        ],
        "venue": "Yingyong Kexue Xuebao/Journal of Applied Sciences",
        "year": 2011,
        "id": "wZKoazye"
    },
    "JBIe43ZX": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Feng Jiang",
                "org": ""
            }
        ],
        "title": "A rough set based decision tree algorithm and its application in intrusion detection",
        "abstract": "In this paper, we propose a novel rough set based algorithm to induce decision trees. To improve the computation efficiency of our algorithm, the rough set based attribute reduction technology is used to filter out the irrelevant attributes from the original set of attributes. And the notions of the significance of attribute and the uniformity of attribute in rough sets are adopted as the heuristic information for the selection of splitting attributes. Moreover, we apply the proposed algorithm to intrusion detection. The experimental results demonstrate that our algorithm can provide competitive solutions efficiently. \u00a9 2011 Springer-Verlag Berlin Heidelberg.",
        "keywords": [
            "decision trees",
            "intrusion detection",
            "Rough sets",
            "significance of attribute",
            "uniformity of attribute"
        ],
        "venue": "Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)",
        "year": 2011,
        "id": "JBIe43ZX"
    },
    "FST2kK2j": {
        "authors": [
            {
                "name": "Jian-Min Qi",
                "org": "China Academy of Engineering Physics"
            },
            {
                "name": "Lin Zhou",
                "org": "China Academy of Engineering Physics"
            },
            {
                "name": "Shi-Lun Jiang",
                "org": "China Academy of Engineering Physics"
            },
            {
                "name": "Tai-Ping Peng",
                "org": "China Academy of Engineering Physics"
            }
        ],
        "title": "Energy calibration of magnetic analysis system for compact magnetic proton recoil spectrometer",
        "abstract": "A magnetic analysis system for a compact magnetic proton recoil spectrometer dedicated to pulse DT neutron spectroscopy in special experimental environments was presented. Performance of the system was analyzed using 3-D particle transport calculation and Monte-Carlo simulation. Energy calibration of the system was obtained using CR-39 track detector and mono-energetic \u03b1 particles. The results indicate that the magnetic analysis system has achieved satisfactory performance on energy dispersion and focusing. It can achieve a detection efficiency of approximately (0.5-1.4)\u00d710\n                        ",
        "keywords": [
            "CR-39",
            "Energy calibration",
            "Fusion neutron",
            "Magnetic proton recoil"
        ],
        "venue": "Yuanzineng Kexue Jishu/Atomic Energy Science and Technology",
        "year": 2011,
        "id": "FST2kK2j"
    },
    "wizNjMx2": {
        "authors": [
            {
                "name": "Yi Shu",
                "org": "College of Mechanical Engineering and Automation"
            },
            {
                "name": "Lin Zhou",
                "org": "College of Mechanical Engineering and Automation"
            },
            {
                "name": "Yi-Fan Dai",
                "org": "College of Mechanical Engineering and Automation"
            },
            {
                "name": "Yong-Xiang Shen",
                "org": "College of Mechanical Engineering and Automation"
            },
            {
                "name": "Xu-Hui Xie",
                "org": "College of Mechanical Engineering and Automation"
            },
            {
                "name": "Sheng-Yi Li",
                "org": "College of Mechanical Engineering and Automation"
            }
        ],
        "title": "Study on surface roughness of KDP crystal in ion beam figuring",
        "abstract": "In order to avoid surface scratches and impurities of the KDP(Potassium dihydrogen phosphate) crystal generated in the process of traditional machining, which would decrease the laser damage threshold, the research is aiming at realizing the machining of KDP crystal by ion beam figuring technology. The experimental study is mainly carried out to analyze the evolvement of surface roughness on KDP crystal. Surface roughness of KDP crystals were studied by normally incidence and obliquely incidence at 45\u00b0. The surface RMS roughness is reduced from 3.07 nm to 1.95 nm by the oblique incidence figuring method with the incidence angle at 45\u00b0. Experimental results validate the feasibility of ion beam figuring of KDP crystal.",
        "keywords": [
            "Ion beam figuring(IBF)",
            "KDP crystal",
            "Surface roughness"
        ],
        "venue": "Rengong Jingti Xuebao/Journal of Synthetic Crystals",
        "year": 2011,
        "id": "wizNjMx2"
    },
    "AwiqPfOu": {
        "authors": [
            {
                "name": "Sifa Zheng",
                "org": "State Key Laboratory of Automobile Safety and Energy"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Automobile Safety and Energy"
            },
            {
                "name": "Xiaomin Lian",
                "org": "State Key Laboratory of Automobile Safety and Energy"
            },
            {
                "name": "Keqiang Li",
                "org": "State Key Laboratory of Automobile Safety and Energy"
            }
        ],
        "title": "Technical note: Coherence analysis of the transfer function for dynamic force identification",
        "abstract": "Identifying dynamic forces with structural response signals is important when direct measurement is difficult or impossible. The minimized condition number method was introduced to reconstruct the forces with selected spatial distribution of response locations. This paper presents another way to optimize the selection of the response locations. The coherence of transfer function matrix is analyzed and the coherence factor of the transfer function matrix is introduced to optimize the response locations. Numerical simulations of the coherence analysis show that it is effective and requires less computational effort than the condition number method. The validity of the analysis is verified by applying it to the identification of the suspension forces on a vehicle cab. \u00a9 2010 Elsevier Ltd. All rights reserved.",
        "keywords": [
            "Coherence factor analysis",
            "Condition number method",
            "Force identification",
            "Ill-posed problem"
        ],
        "venue": "Mechanical Systems and Signal Processing",
        "year": 2011,
        "id": "AwiqPfOu"
    },
    "gtJbiti0": {
        "authors": [
            {
                "name": "Hongwei Xie",
                "org": ""
            },
            {
                "name": "Hongyun Li",
                "org": ""
            },
            {
                "name": "Zeping Xu",
                "org": ""
            },
            {
                "name": "Guzhou Song",
                "org": ""
            },
            {
                "name": "Faqiang Zhang",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            }
        ],
        "title": "A novel data processing technique for image reconstruction of penumbral imaging",
        "abstract": "CT image reconstruction technique was applied to the data processing of the penumbral imaging. Compared with other traditional processing techniques for penumbral coded pinhole image such as Wiener, Lucy-Richardson and blind technique, this approach is brand new. In this method, the coded aperture processing method was used for the first time independent to the point spread function of the image diagnostic system. In this way, the technical obstacles was overcome in the traditional coded pinhole image processing caused by the uncertainty of point spread function of the image diagnostic system. Then based on the theoretical study, the simulation of penumbral imaging and image reconstruction was carried out to provide fairly good results. While in the visible light experiment, the point source of light was used to irradiate a 5mmx5mm object after diffuse scattering and volume scattering. The penumbral imaging was made with aperture size of \u223c20mm. Finally, the CT image reconstruction technique was used for image reconstruction to provide a fairly good reconstruction result. \u00a9 2011 Copyright Society of Photo-Optical Instrumentation Engineers (SPIE).",
        "keywords": [
            "coded aperture imaging",
            "CT (Computer Tomography) image reconstruction",
            "image super-resolution",
            "penumbral imaging"
        ],
        "venue": "Proceedings of SPIE - The International Society for Optical Engineering",
        "year": 2011,
        "id": "gtJbiti0"
    },
    "SHZlsCt0": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "School of Electronic Science and Engineering"
            },
            {
                "name": "Huai-Jun Wang",
                "org": "School of Electronic Science and Engineering"
            },
            {
                "name": "Yi Su",
                "org": "School of Electronic Science and Engineering"
            }
        ],
        "title": "GPR imaging algorithm based on compressive sensing",
        "abstract": "The Nyquist sampling theorem must be satisfied in traditional data acquisition of the ground penetrating radar (GPR), which degrades the imaging efficiency dramatically. However, the theory of compressive sensing (CS) shows that sparse signals can be precisely reconstructed by solving a convex l",
        "keywords": [
            "Back projection algorithm",
            "Compressive sensing",
            "Ground penetrating radar imaging",
            "Nyquist sampling theorem"
        ],
        "venue": "Xi Tong Gong Cheng Yu Dian Zi Ji Shu/Systems Engineering and Electronics",
        "year": 2011,
        "id": "SHZlsCt0"
    },
    "egqB2tVN": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "School of Electronic Science and Engineering"
            },
            {
                "name": "Yi Su",
                "org": "School of Electronic Science and Engineering"
            }
        ],
        "title": "GPR imaging with RM algorithm in layered mediums",
        "abstract": "In ground-penetrating radar (GPR) imaging, the classic range migration (RM) algorithm can work well only when the imaging scene can be modeled as a single homogeneous medium. However, in most GPR field applications, the GPR system and objects operate in different mediums. The space between the antennas and the ground cannot be ignored electromagnetically. In this kind of circumstance, the imaging result of the classic RM algorithm will be blurred or possibly not focused at all, and the object's physical location cannot be interpreted from the imaging result. A layered RM imaging algorithm is proposed in this letter. With the exploding source model, the received field is first back propagated to the ground surface, and then, the classic RM method is carried out to give the final imaging result. Experimental results show that the proposed algorithm can prevent the defocusing of the object and obtain the object's true position. The computational time of the layered RM algorithm does not increase remarkably compared with that of the classic RM algorithm. \u00a9 2011 IEEE.",
        "keywords": [
            "Exploding source model (ESM)",
            "ground-penetrating radar (GPR)",
            "radar imaging",
            "range migration (RM)"
        ],
        "venue": "IEEE Geoscience and Remote Sensing Letters",
        "year": 2011,
        "id": "egqB2tVN"
    },
    "brx406cw": {
        "authors": [
            {
                "name": "Jia Li",
                "org": "School of Automation and Electrical Engineering"
            },
            {
                "name": "Rong-Hu Chi",
                "org": "School of Automation and Electrical Engineering"
            },
            {
                "name": "Lin Zhou",
                "org": "Science and Technology Division"
            }
        ],
        "title": "Adaptive iterative learning control with dead zone scheme",
        "abstract": "For a class of nonlinear systems with time-varying parametric uncertainties, a new adaptive iterative learning control (AILC) approach with dead zone scheme is proposed to address the problem of bounded noise. The design and analysis does not require the identical initial conditions and the assumption that the reference trajectory must not be varying along the iterative axis. The effectiveness and boundedness of the proposed method is guaranteed theoretically with the rigorous mathematical analysis. \u00a9 2011 Chinese Assoc of Automati.",
        "keywords": [
            "Adaptive Control",
            "Dead Zone Scheme",
            "Iterative Learning Control",
            "Projection Algorithm",
            "Time-Varying Parameter"
        ],
        "venue": "Proceedings of the 30th Chinese Control Conference, CCC 2011",
        "year": 2011,
        "id": "brx406cw"
    },
    "yAsnogL9": {
        "authors": [
            {
                "name": "Baode Jiang",
                "org": "Faculty of Information Engineering"
            },
            {
                "name": "Zhong Xie",
                "org": "Faculty of Information Engineering"
            },
            {
                "name": "Xincai Wu",
                "org": "Faculty of Information Engineering"
            },
            {
                "name": "Liang Wu",
                "org": "Faculty of Information Engineering"
            },
            {
                "name": "Lin Zhou",
                "org": "Faculty of Information Engineering"
            }
        ],
        "title": "Topology constrain for river dimension-reducing generalization in land-use map",
        "abstract": "Topological consistency which plays an important role in land-use map is a difficult problem for map auto generalization. This paper concentrates on the topological preserving of river's dimension-reducing generalization in the land-use map. We propose a method for handling the conflicting constraints involved in generalizing a river polygon (double-line river) into a single-line river. It includes mainly two steps: First, extract the medial axis as a centerline for river polygon base on the constrained delaunay triangulation model. Then, expand the polygons' boundaries which are shared by the double-line river's bank towards the collapsed river's centerlines base on the topology and computational geometry. Experiments are tested against land-use maps at 1:10k scale. The results illustrate that this method can keep the topological constraint well for river dimension-reducing generalization in land-use map. \u00a9 2011 IEEE.",
        "keywords": [
            "dimension-reducing processing",
            "land-use map",
            "map auto generalization",
            "topology constrain"
        ],
        "venue": "Proceedings - 2011 19th International Conference on Geoinformatics, Geoinformatics 2011",
        "year": 2011,
        "id": "yAsnogL9"
    },
    "6jkHZRrr": {
        "authors": [
            {
                "name": "Xuhui Xie",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Yifan Dai",
                "org": ""
            },
            {
                "name": "Shengyi Li",
                "org": ""
            }
        ],
        "title": "Ion beam machining error control and correction for small scale optics",
        "abstract": "Ion beam figuring (IBF) technology for small scale optical components is discussed. Since the small removal function can be obtained in IBF, it makes computer-controlled optical surfacing technology possible to machine precision centimeter- or millimeter-scale optical components deterministically. Using a small ion beam to machine small optical components, there are some key problems, such as small ion beam positioning on the optical surface, material removal rate, ion beam scanning pitch control on the optical surface, and so on, that must be seriously considered. The main reasons for the problems are that it is more sensitive to the above problems than a big ion beam because of its small beam diameter and lower material ratio. In this paper, we discuss these problems and their influences in machining small optical components in detail. Based on the identification-compensation principle, an iterative machining compensation method is deduced for correcting the positioning error of an ion beam with the material removal rate estimated by a selected optimal scanning pitch. Experiments on \u03c610mm Zerodur planar and spherical samples are made, and the final surface errors are both smaller than \u03bb/100 measured by a Zygo GPI interferometer. \u00a9 2011 Optical Society of America.",
        "keywords": [
            ""
        ],
        "venue": "Applied Optics",
        "year": 2011,
        "id": "6jkHZRrr"
    },
    "oNdbZZn9": {
        "authors": [
            {
                "name": "Shilun Jiang",
                "org": "Institute of Nuclear Physics and Chemistry"
            },
            {
                "name": "Jianmin Qi",
                "org": "Institute of Nuclear Physics and Chemistry"
            },
            {
                "name": "Lin Zhou",
                "org": "Institute of Nuclear Physics and Chemistry"
            }
        ],
        "title": "The development of magnetic proton recoil technology",
        "abstract": "The magnetic proton recoil technology is a new diagnostic instrument for fusion neutron spectrometry studies. It has good energy resolution and high signal-to-noise ratio, and is suitable for measurements in mixed fields and large dynamic neutron flux environments. In this paper, we give a review on the magnetic proton recoil spectrometers developed at the world's large fusion facilities, where good results in different fusion experiments have been obtained. They include the magnetic proton recoil spectrometer (MPR) at Joint European Torus (JET), using the magnetic analysis system of two-pole electromagnet and achieving an energy resolution of 2.5%; and the magnetic recoil spectrometer (MRS) at OMEGA, University of Rochester, USA, where the magnetic analysis system is capable of analyzing 6-32 MeV protons and an energy resolution of 3.0% has been achieved. A magnetic proton recoil spectrometer developed at China Academy of Engineering Physics using a 0.79 T permanent magnet, with an efficiency of up to 6.2 \u00d7 10\n                        ",
        "keywords": [
            "Fusion neutron diagnostic",
            "Magnetic analysis",
            "Recoil proton"
        ],
        "venue": "He Jishu/Nuclear Techniques",
        "year": 2011,
        "id": "oNdbZZn9"
    },
    "oaJUqoL5": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "College of Information Science and Technology"
            },
            {
                "name": "Feng Jiang",
                "org": "College of Information Science and Technology"
            }
        ],
        "title": "A rough set approach to feature selection based on relative decision entropy",
        "abstract": "Rough set theory has been recognized to be one of the powerful tools for feature selection. The essence of rough set approach to feature selection is to find a minimal subset (or called reduct) of original features, which can predict the decision concepts as well as the original features. Since finding a minimal feature subset is a NP-hard problem, many heuristic algorithms have been proposed, which usually employ the feature significance in rough sets as heuristic information. Shannon's information theory provides us a feasible way to measure the information of data sets with entropy. Hence, many researchers have used information entropy to measure the feature significance in rough sets, and proposed different information entropy models in rough sets. In this paper, we present a new information entropy model, in which relative decision entropy is defined. Based on the relative decision entropy, we propose a new rough set algorithm to feature selection. To verify the efficiency of our algorithm, experiments are carried out on some UCI data sets. The results demonstrate that our algorithm can provide competitive solutions efficiently. \u00a9 2011 Springer-Verlag.",
        "keywords": [
            "feature selection",
            "information entropy",
            "relative decision entropy",
            "Rough sets"
        ],
        "venue": "Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)",
        "year": 2011,
        "id": "oaJUqoL5"
    },
    "mTKcF9sC": {
        "authors": [
            {
                "name": "Fan Wang",
                "org": "Electronic Information Department"
            },
            {
                "name": "Huotao Gao",
                "org": "Electronic Information Department"
            },
            {
                "name": "Lin Zhou",
                "org": "Electronic Information Department"
            },
            {
                "name": "Qingchen Zhou",
                "org": "Electronic Information Department"
            },
            {
                "name": "Jie Shi",
                "org": "Electronic Information Department"
            },
            {
                "name": "Yuxiang Sun",
                "org": "Electronic Information Department"
            }
        ],
        "title": "Design and FPGA implementation of digital pulse compression for HF chirp radar based on modified orthogonal transformation",
        "abstract": "The paper presents a digital pulse compression approach for high frequency (HF) chirp radar. The emphasis is to accomplish echo signal de-chirp operation by modified orthogonal transformation on field programmable gates array (FPGA) chip. This approach has been developed for an all-digital receiver platform which is directly radio frequency (RF) band-pass sampling, compared with the traditional analog receiver or intermediate frequency (IF) receiver, it has an easy hardware structure closing to a \"soft\" radar mode. The system closed-loop test shows the correctness and rationality of the design, meeting the demand of engineering application. \u00a9 IEICE 2011.",
        "keywords": [
            "All-digital receiver",
            "Digital down converter",
            "Digital pulse compression",
            "Field programmable gates array",
            "Orthogonal transformation"
        ],
        "venue": "IEICE Electronics Express",
        "year": 2011,
        "id": "mTKcF9sC"
    },
    "kzVp3R6f": {
        "authors": [
            {
                "name": "Fan Wang",
                "org": "Electronic Information Department"
            },
            {
                "name": "Huotao Gao",
                "org": "Electronic Information Department"
            },
            {
                "name": "Lin Zhou",
                "org": "Electronic Information Department"
            }
        ],
        "title": "A design of multi-frequency high-frequency radar receiver system",
        "abstract": "For high-frequency radar, ship targets detection is seriously affected by the strong sea clutter. To solve the problem, a design of multi-frequency radar receiver system is presented, which completes digital mixer and digital down converter for multi-channel digital receivers based on FPGA and carries out system controls and data transmission by USB2.0 interface. The system closed-loop test shows that the scheme can work in multi-frequency mode which meets the requirements of HF radar application. \u00a9 2011 IEEE.",
        "keywords": [
            "Digital down converter",
            "Field programmable gate array",
            "High frequency radar",
            "Multi-frequency radar",
            "Orthogonal transformation"
        ],
        "venue": "7th International Conference on Wireless Communications, Networking and Mobile Computing, WiCOM 2011",
        "year": 2011,
        "id": "kzVp3R6f"
    },
    "Y2nYW73Y": {
        "authors": [
            {
                "name": "Fan Wang",
                "org": "Electronic Information Department"
            },
            {
                "name": "Huo-Tao Gao",
                "org": "Electronic Information Department"
            },
            {
                "name": "Lin Zhou",
                "org": "Electronic Information Department"
            },
            {
                "name": "Yu-Xiang Sun",
                "org": "Electronic Information Department"
            }
        ],
        "title": "Hardware implementation of MUSIC algorithm for airborne digital direction finding system",
        "abstract": "To solve the issue of high complexity and poor real time in conventional array direction finding system of multiple signal classification algorithms, a digital solution based on field programmable gate array (FPGA) is presented. The solution includes real time quadrate demodulation and pretreatment, coordinate rotation digital computing (CORDIC) algorithm in rotation mode to realize singular value decomposition in order to reduce computation, and finally achieves the real time array direction finding. Hardware simulation and tests show that the system works stably and can ensure the deviation is less than 0.5 degree with over 64 snapshots, which can be used in precise positioning and measurement. \u00a9 2011 IEEE.",
        "keywords": [
            "Coordinate rotation digital computing",
            "Direction finding",
            "Direction of arrival estimation",
            "Field programmable gate array",
            "Multiple signal classification"
        ],
        "venue": "7th International Conference on Wireless Communications, Networking and Mobile Computing, WiCOM 2011",
        "year": 2011,
        "id": "Y2nYW73Y"
    },
    "NrjrUvpx": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "School of Electronic Science and Engineering"
            },
            {
                "name": "Yi Su",
                "org": "School of Electronic Science and Engineering"
            }
        ],
        "title": "A ground penetrating radar back projection imaging algorithm based on cross-correlation",
        "abstract": "Based on the cross-correlation of the received data of Ground Penetrating Radar (GPR), a novel Back Projection (BP) algorithm is proposed to suppress the artifacts in the results of GPR imaging. Comparing with standard BP algorithm, the proposed Cross-correlated Back Projection (CBP) algorithm adds the procedure of calculating the cross-correlation of the received data without increasing any additional channel for reference signal. Both the theoretical analysis and the experimental results present the superiority of the CBP algorithm over standard BP algorithm in artifacts suppression, as well as a slightly improvement in image resolution.",
        "keywords": [
            "Back Projection (BP)",
            "Ground Penetrating Radar (GPR)",
            "Radar imaging",
            "Synthetic aperture"
        ],
        "venue": "Dianzi Yu Xinxi Xuebao/Journal of Electronics and Information Technology",
        "year": 2011,
        "id": "NrjrUvpx"
    },
    "aZ9Vw0XG": {
        "authors": [
            {
                "name": "Xiaowei Zhang",
                "org": "School of Information Science and Engineering"
            },
            {
                "name": "Bin Hu",
                "org": "School of Computing, Telecommunications and Networks"
            },
            {
                "name": "Philip Moore",
                "org": "School of Computing, Telecommunications and Networks"
            },
            {
                "name": "Jing Chen",
                "org": "School of Information Science and Engineering"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Information Science and Engineering"
            }
        ],
        "title": "Emotiono: An ontology with rule-based reasoning for emotion recognition",
        "abstract": "Recently, the field of automatic recognition of users' affective states has gained a great deal of attention. Automatic, implicit recognition of affective states has many applications, ranging from personalized content recommendation to automatic tutoring systems. In this work, we propose an ontology called 'Emotiono' for the robust recognition of emotions through Electroencephalogram (EEG). In 'Emotiono', we define entities such as users' emotions, EEG features and their relationships. With inference rules obtained by Decision Tree algorithm, users' current emotional state can be reasoned based on their EEG data. We implement 'Emotiono' in Prot\u00e9g\u00e9 4.1 and evaluate its performance with EEG data gathered from the eNTERFACE06-EMOBRAIN Database. Using a 9-fold cross validation method for training and testing, 'Emotiono' reaches an average classification rate of 97.80% for recognizing 5 subjects' emotional states. \u00a9 2011 Springer-Verlag.",
        "keywords": [
            "Decision Tree",
            "EEG",
            "Emotion",
            "Ontology"
        ],
        "venue": "Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)",
        "year": 2011,
        "id": "aZ9Vw0XG"
    },
    "2ItthCH9": {
        "authors": [
            {
                "name": "Hongjun Wang",
                "org": "Department of Physics"
            },
            {
                "name": "Changwei Zou",
                "org": "Department of Physics"
            },
            {
                "name": "Canxin Tian",
                "org": "Department of Physics"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Physics"
            },
            {
                "name": "Zesong Wang",
                "org": "Department of Physics"
            },
            {
                "name": "Dejun Fu",
                "org": "Key Laboratory of Beam Technology and Materials Modification of Ministry of Education"
            }
        ],
        "title": "A novel gas ionization sensor using pd nanoparticle-capped zno",
        "abstract": "A novel gas ionization sensor using Pd nanoparticle-capped ZnO (Pd/ZnO) nanorods as the anode is proposed. The Pd/ZnO nanorod-based sensors, compared with the bare ZnO nanorod, show lower breakdown voltage for the detected gases with good sensitivity and selectivity. Moreover, the sensors exhibit stable performance after more than 200 tests for both inert and active gases. The simple, low-cost, Pd/ZnO nanorod-based field-ionization gas sensors presented in this study have potential applications in the field of gas sensor devices. \u00a9 2011 Wang et al.",
        "keywords": [
            ""
        ],
        "venue": "Nanoscale Research Letters",
        "year": 2011,
        "id": "2ItthCH9"
    },
    "m2fB2NQm": {
        "authors": [
            {
                "name": "Zheng Yuan",
                "org": "School of Mechatronics Engineering and Automation"
            },
            {
                "name": "Yifan Dai",
                "org": "School of Mechatronics Engineering and Automation"
            },
            {
                "name": "Hao Yu",
                "org": "School of Mechatronics Engineering and Automation"
            },
            {
                "name": "Xuhui Xie",
                "org": "School of Mechatronics Engineering and Automation"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Mechatronics Engineering and Automation"
            }
        ],
        "title": "Control of thermal effect in ion beam figuring process based on low-pass filtering",
        "abstract": "During ion beam figuring process, most heat energy is absorbed by optics surface, heating the workpiece surface un-uniformly, called thermal effect. Thermal effect leads to distortion even cracking of the optical figure due to high temperature and temperature gradients, especially for the temperature sensible materials such as BK7, KDP and CaF ",
        "keywords": [
            "Ion beam figuring",
            "Low-pass filtering",
            "Temperature sensible materials",
            "Thermal effect"
        ],
        "venue": "Applied Mechanics and Materials",
        "year": 2012,
        "id": "m2fB2NQm"
    },
    "iW7IGuIM": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "College of Information Science and Technology, Qingdao University of Science and Technology"
            },
            {
                "name": "Chunping Wang",
                "org": "College of Computer Science and Technology, Zhejiang University of Technology"
            },
            {
                "name": "Feng Jiang",
                "org": "College of Information Science and Technology, Qingdao University of Science and Technology"
            }
        ],
        "title": "A rough set based alerts aggregation and correlation model for intrusion detection",
        "abstract": "In recent years, much attention has been given to the aggregation and correlation of alerts in intrusion detection. Since the amount of alerts generated from intrusion detection systems can be overwhelming, it is necessary to develop an efficient framework for the management of alerts. In this paper, we propose a hierarchical model for the aggregation and correlation of alerts based on rough set theory. Our model is divided into three levels: alerts completion, alerts aggregation and alerts correlation. For the first level, we propose a rough set based alerts completion algorithm, which can be used to deal with the missing values in the incomplete alerts and filter the invalid alerts. For the second level, we propose a rough set based attribute reduction algorithm, which can be used to aggregate the duplicate alerts from the view of time dimension and space dimension. For the third level, we use a rough set based clustering algorithm to correlate related alerts and uncover the attack strategies.",
        "keywords": [
            "Alerts aggregation",
            "Alerts completion",
            "Alerts correlation",
            "Intrusion detection",
            "Rough sets"
        ],
        "venue": "TEIN 2012 - 2012 3rd International Conference on Telecommunication and Information",
        "year": 2012,
        "id": "iW7IGuIM"
    },
    "4CvW1e9T": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "School of Electronic Science and Engineering"
            },
            {
                "name": "Chunlin Huang",
                "org": "School of Electronic Science and Engineering"
            },
            {
                "name": "Yi Su",
                "org": "School of Electronic Science and Engineering"
            }
        ],
        "title": "A fast back-projection algorithm based on cross correlation for GPR imaging",
        "abstract": "In ground-penetrating radar imaging, the classic back-projection (BP) algorithm has an excellent reputation for imaging in layered mediums with convenience and robustness. However, the classic BP algorithm is time consuming and with a lot of artifacts, which have adverse effects on the following work like detection and recognition. A novel BP algorithm, which is both fast and with good effect of suppressing artifacts, is proposed in this letter. At first, an approved approximation method is used to calculate the position of refraction point with remarkable speed and satisfactory accuracy. Then, a lookup table is used to reduce the redundancy in classic BP algorithm. In order to achieve effective artifact suppression, a cross-correlation-based method is introduced. Experimental results of field data present the superiority of the proposed BP algorithm over its classic counterpart both in operation speed and artifact suppression. \u00a9 2006 IEEE.",
        "keywords": [
            "Back projection (BP)",
            "cross correlation",
            "ground-penetrating radar (GPR)",
            "radar imaging"
        ],
        "venue": "IEEE Geoscience and Remote Sensing Letters",
        "year": 2012,
        "id": "4CvW1e9T"
    },
    "XzuAf3h8": {
        "authors": [
            {
                "name": "Mingjun Wei",
                "org": "Department of Mechanical and Aerospace Engineering"
            },
            {
                "name": "Bashar R. Qawasmeh",
                "org": "Department of Mechanical and Aerospace Engineering"
            },
            {
                "name": "Matthew Barone",
                "org": "Sandia National Laboratories"
            },
            {
                "name": "Bart G. van Bloemen Waanders",
                "org": "Sandia National Laboratories"
            },
            {
                "name": "Lin Zhou",
                "org": "Modern Mechanics Department"
            }
        ],
        "title": "Low-dimensional model of spatial shear layers",
        "abstract": "The aim of this work is to develop nonlinear low-dimensional models to describe vortex dynamics in spatially developing shear layers with periodicity in time. By allowing a free variable g (\u03a7) to dynamically describe downstream thickness spreading, we are able to obtain basis functions in a scaled reference frame and construct effective models with only a few modes in the new space. To apply this modified version of proper orthogonal decomposition (POD)/Galerkin projection, we first scale the flow along y dynamically to match a template function as it is developing downstream. In the scaled space, the first POD mode can capture more than 80% energy for each frequency. However, to construct a Galerkin model, the second POD mode plays a critical role and needs to be included. Finally, a reconstruction equation for the scaling variable g is derived to relate the scaled space to physical space, where downstream spreading of shear thickness occurs. Using only two POD modes at each frequency, our models capture the basic dynamics of shear layers, such as vortex roll-up (from a one-frequency model) and vortex-merging (from a two-frequency model). When arbitrary excitation at different harmonics is added to the model, we can clearly observe the promoting or delaying/eliminating vortex merging events as a result of mode competition, which is commonly demonstrated in experiments and numerical simulations of shear layers. \u00a9 2012 American Institute of Physics.",
        "keywords": [
            ""
        ],
        "venue": "Physics of Fluids",
        "year": 2012,
        "id": "XzuAf3h8"
    },
    "gWS5MSiD": {
        "authors": [
            {
                "name": "Xuhui Xie",
                "org": "National University of Defense Technology"
            },
            {
                "name": "Yu Hao",
                "org": "National University of Defense Technology"
            },
            {
                "name": "Lin Zhou",
                "org": "National University of Defense Technology"
            },
            {
                "name": "Yifan Dai",
                "org": "National University of Defense Technology"
            },
            {
                "name": "Shengyi Li",
                "org": "National University of Defense Technology"
            }
        ],
        "title": "High thermal expansion optical component machined by ion beam figuring",
        "abstract": "Ion beam figuring (IBF) Technology to fabricate optical materials with a high thermal expansion coefficient, such as BK7, we were aware that the thermal effect is a troublesome problem that generates high thermal stress. If the thermal stress is over the component mechanical stress limit, the component may crack or break. We discuss this problem in detail and set up a thermal model. Using this model, we gain the machined component temperature field and its corresponding thermal stress field. A filtered IBF method is created to correct the thermal stress field which that gain a more even thermal stress distribution and decrease the thermal stress about 20%. \u00a9 2012 Society of Photo-Optical Instrumentation Engineers.",
        "keywords": [
            "high thermal expansion optics",
            "ion beam figuring",
            "thermal stress control"
        ],
        "venue": "Optical Engineering",
        "year": 2012,
        "id": "gWS5MSiD"
    },
    "tBCYu0VS": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Zhengzhou Information Science and Technology Institute"
            },
            {
                "name": "Xijian Ping",
                "org": "Zhengzhou Information Science and Technology Institute"
            },
            {
                "name": "Haolin Gao",
                "org": "Zhengzhou Information Science and Technology Institute"
            },
            {
                "name": "Sen Xu",
                "org": "Yancheng Institute of Technology"
            }
        ],
        "title": "A novel video image text detection method",
        "abstract": "A novel and universal method of video image text detection is proposed. A coarse-to-fine text detection method is implemented. Firstly, the spectral clustering (SC) method is adopted to coarsely detect text regions based on the stationary wavelet transform (SWT). In order to make full use of the information, multi-parameters kernel function which combining the features similarity information and spatial adjacency information is employed in the SC method. Secondly, 28 dimension classifying features are proposed and support vector machine (SVM) is implemented to classify text regions with non-text regions. Experimental results on video images show the encouraging performance of the proposed algorithm and classifying features. \u00a9 2012 KSII.",
        "keywords": [
            "Multi-parameters kernel function",
            "SC algorithm",
            "SVM",
            "Text detection"
        ],
        "venue": "KSII Transactions on Internet and Information Systems",
        "year": 2012,
        "id": "tBCYu0VS"
    },
    "pVIIlGig": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "School of Automation"
            },
            {
                "name": "Yan Liang",
                "org": "School of Automation"
            },
            {
                "name": "Quan Pan",
                "org": "School of Automation"
            }
        ],
        "title": "System error registration based on Metropolis-Hastings sampling",
        "abstract": "In order to resolve system error registration in target tracking system which has inadequacy maneuvering model, a novel system error registration method based on Metropolis-Hastings sampling is proposed. This method gains an equivalent probability density distribution function derived from system error maximum likelihood estimation and regards it as a probability density function suitable for Metropolis-Hastings sampling. Besides, using different proposal functions to improve sample overall capacity in system error space. Two scenes which include time-vaying and time-unvarying system errors are simulated. Simulation results show that this method not only considers the statistical characteristics of system errors but also resolves the registration of system errors.",
        "keywords": [
            "Error registration",
            "Maximum likelihood estimate",
            "Metropolis-Hastings sampling",
            "System error"
        ],
        "venue": "Xi Tong Gong Cheng Yu Dian Zi Ji Shu/Systems Engineering and Electronics",
        "year": 2012,
        "id": "pVIIlGig"
    },
    "KJJG7rCy": {
        "authors": [
            {
                "name": "Wenlin Liao",
                "org": "National University of Defense Technology"
            },
            {
                "name": "Yifan Dai",
                "org": "National University of Defense Technology"
            },
            {
                "name": "Xuhui Xie",
                "org": "National University of Defense Technology"
            },
            {
                "name": "Lin Zhou",
                "org": "National University of Defense Technology"
            },
            {
                "name": "Zheng Yuan",
                "org": "National University of Defense Technology"
            }
        ],
        "title": "Corrective capability analysis and machining error control in ion beam figuring of high-precision optical mirrors",
        "abstract": "In deterministic ion beam figuring (IBF) technology, the application of small ion beam enhances the corrective capability for mid-to-high spatial frequency errors on the optical surface, which directly determines the surface accuracy of the figuring process. But when the diameter of the ion beam becomes smaller, the machining errors will have a stronger influence on the final figuring result, so these errors must be controlled through corresponding methods. We investigate the corrective principle in IBF for surface errors of different spatial frequencies and establish the selection criterion for removal function in different figuring stages to realize the rapid convergence of surface accuracy. Then, through analyzing and controlling the machining errors in the figuring process, high-precision mirrors can be rapidly obtained. Finally, experiments on fused silica planar and spherical samples are conducted on our self-developed IBF system, and their final surface accuracy are both smaller than 1.1 nm RMS (root-mean-square) and 12.0 nm PV (Peak-to-Valley) after several iterations within 20 min. \u00a9 2012 Society of Photo-Optical Instrumentation Engineers (SPIE).",
        "keywords": [
            "Corrective capability",
            "Ion beam figuring",
            "Machining error control",
            "Small ion beam"
        ],
        "venue": "Optical Engineering",
        "year": 2012,
        "id": "KJJG7rCy"
    },
    "EjD9hzHR": {
        "authors": [
            {
                "name": "Hongjun Wang",
                "org": "Department of Physics"
            },
            {
                "name": "Changwei Zou",
                "org": "Department of Physics"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Physics"
            },
            {
                "name": "Canxin Tian",
                "org": "Department of Physics"
            },
            {
                "name": "Dejun Fu",
                "org": "Department of Physics"
            }
        ],
        "title": "Resistive switching characteristics of thin NiO film based flexible nonvolatile memory devices",
        "abstract": "Flexible resistive switching device consisting of thin NiO film sandwiched between a flexible Cu foil substrate and Ti top electrode is proposed in this work. The Ti/NiO/Cu structure was fabricated by radio frequency magnetron sputtering deposition of a NiO film on the flexible Cu foil substrate. The fabricated device showed stable bipolar resistive switching behavior and its performance was not degraded upon different bending states. The Ti/NiO/Cu flexible device presented in our work has potential applications in the field of resistive switching random access memory (RRAM) devices. \u00a9 2011 Elsevier B.V. All rights reserved.",
        "keywords": [
            "NiO",
            "Nonvolatile memory",
            "Resistance switching",
            "RRAM"
        ],
        "venue": "Microelectronic Engineering",
        "year": 2012,
        "id": "EjD9hzHR"
    },
    "tKceNeIU": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Zhengzhou Information Science and Technology Institute"
            },
            {
                "name": "Xijian Ping",
                "org": "Zhengzhou Information Science and Technology Institute"
            },
            {
                "name": "Haolin Gao",
                "org": "Zhengzhou Information Science and Technology Institute"
            },
            {
                "name": "Sen Xu",
                "org": "Yancheng Institute of Technology"
            }
        ],
        "title": "A novel video image text detection method",
        "abstract": "A novel and universal method of video image text detection is proposed. A coarse-to-fine text detection method is implemented. Firstly, the spectral clustering (SC) method is adopted to coarsely detect text regions based on the stationary wavelet transform (SWT). In order to make full use of the information, multi-parameters kernel function which combining the features similarity information and spatial adjacency information is employed in the SC method. Secondly, 28 dimension classifying features are proposed and support vector machine (SVM) is implemented to classify text regions with non-text regions. Experimental results on video images show the encouraging performance of the proposed algorithm and classifying features. \u00a9 2012 KSII.",
        "keywords": [
            "Multi-parameters kernel function",
            "SC algorithm",
            "SVM",
            "Text detection"
        ],
        "venue": "KSII Transactions on Internet and Information Systems",
        "year": 2012,
        "id": "tKceNeIU"
    },
    "5aj25TQ5": {
        "authors": [
            {
                "name": "Wenlin Liao",
                "org": "National University of Defense Technology"
            },
            {
                "name": "Yifan Dai",
                "org": "National University of Defense Technology"
            },
            {
                "name": "Xuhui Xie",
                "org": "National University of Defense Technology"
            },
            {
                "name": "Lin Zhou",
                "org": "National University of Defense Technology"
            },
            {
                "name": "Ziwen Zheng",
                "org": "National University of Defense Technology"
            },
            {
                "name": "Chao Xie",
                "org": "National University of Defense Technology"
            }
        ],
        "title": "Three-dimensional surface error reconstruction and ion beam figuring of optical hemisphere",
        "abstract": "This research is aiming at exploring a feasible machining method for ultra-high slope surface with deterministic figuring technology. We first successfully realize the nanometer-precision machining of optical hemispherical surface by using ion beam figuring (IBF) under the guidance of the reconstructed three-dimensional (3D) surface error. For figuring such a high-slope surface, we proposed some technical details, the modified algorithm for dwell time, the nonlinear developing method of surface error and the stitching machining technology, to address some important problems in process. Simultaneity a fused silica hemispherical surface is figured with our proposed method on the experimental installation IBF700-5V developed by ourselves. The root-mean-square (RMS) surface error of this sample is reduced from 19.6 nm to 9.6 nm after four iterations and about 37.8min. The experimental results indicate that IBF is a technique of high efficiency for the nanometer-precision machining of high-slope surface. \u00a9 (2012) Trans Tech Publications.",
        "keywords": [
            "3D surface error reconstruction",
            "High-slope surface",
            "Ion beam figuring (IBF)",
            "Nanometer-precision machining",
            "Optical hemisphere"
        ],
        "venue": "Advanced Materials Research",
        "year": 2012,
        "id": "5aj25TQ5"
    },
    "cE9XBXOl": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Institute of Nuclear Physics and Chemistry"
            },
            {
                "name": "Shi-Lun Jiang",
                "org": "Institute of Nuclear Physics and Chemistry"
            },
            {
                "name": "Jian-Min Qi",
                "org": "Institute of Nuclear Physics and Chemistry"
            },
            {
                "name": "Li-Zong Wang",
                "org": "Institute of Nuclear Physics and Chemistry"
            }
        ],
        "title": "Study of magnetic proton recoil technology for measurement of deuterium-tritium neutron Spectrum",
        "abstract": "A kind of fusion dianostics based on proton recoil method and magnetic analyzing technology is introduced. It can be used for the accurate diagnoses of plama tempreture, fuel density and neutron yield. A prototype is designed, using a high-powered Nd-Fe-B permanent dipole for magnetic analyzer, and proton position distribution in the focal plane is measured by CR-39 trajectory detector or PIN detector. The system is calibrated with a ",
        "keywords": [
            "Deuterium-tritium (DT) fusion",
            "Magnetic analyzing",
            "Neutron spectrum",
            "Proton recoil"
        ],
        "venue": "Wuli Xuebao/Acta Physica Sinica",
        "year": 2012,
        "id": "cE9XBXOl"
    },
    "tIAdeM0R": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "School of Electronic Science and Engineering"
            },
            {
                "name": "Chun-Lin Huang",
                "org": "School of Electronic Science and Engineering"
            },
            {
                "name": "Yi Su",
                "org": "School of Electronic Science and Engineering"
            }
        ],
        "title": "A ground penetrating radar imaging algorithm based on robust capon beamforming",
        "abstract": "The conventional Ground Penetrating Radar (GPR) imaging algorithms are data-independent, which cause lots of interference like side lobes and clutter. However, the data-adaptive methods have remarkable capability of interference suppression. A data-adaptive GPR imaging algorithm based on the theory of Robust Capon Beamforming (RCB) is proposed. The refraction phenomenon of electromagnetic wave is fully considered, and the generation of covariance matrix is also deeply discussed. The sidelobes and clutter can be suppressed dramatically, as well as the imaging resolution can be slightly improved. The experimental results show the validity of the proposed algorithm.",
        "keywords": [
            "Beamforming",
            "Ground Penetrating Radar (GPR)",
            "Radar imaging",
            "Synthetic aperture"
        ],
        "venue": "Dianzi Yu Xinxi Xuebao/Journal of Electronics and Information Technology",
        "year": 2012,
        "id": "tIAdeM0R"
    },
    "iT6JYYa2": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Institute of Information Engineering"
            },
            {
                "name": "Xi-Jian Ping",
                "org": "Institute of Information Engineering"
            },
            {
                "name": "Li Tong",
                "org": "Institute of Information Engineering"
            }
        ],
        "title": "Texture classification based on improved basic image features histogram",
        "abstract": "An improved method of basic image features (BIF) histogram is proposed. Firstly, corresponding BIF of every pixel in the image is respectively computed in four scales. Secondly, six histogram features and three high order statistical features are extracted respectively in every scale. Finally, the support vector machine (SVM) is applied for training and classifying the texture images. Experiment results show that the proposed method can reduce the computing complexity and consuming time, meanwhile, it is robust to noise.",
        "keywords": [
            "Basic image feature (BIF)",
            "Image processing",
            "Nearest neighbor algorithm",
            "Support vector machine (SVM)",
            "Texture classification"
        ],
        "venue": "Xi Tong Gong Cheng Yu Dian Zi Ji Shu/Systems Engineering and Electronics",
        "year": 2012,
        "id": "iT6JYYa2"
    },
    "OSsbcEaK": {
        "authors": [
            {
                "name": "Yu Zhou",
                "org": "School of Mechanical Electronic and Information Engineering"
            },
            {
                "name": "Anfu Zhu",
                "org": "School of Electric Power"
            },
            {
                "name": "Lin Zhou",
                "org": "Research Institute of Information Technology"
            },
            {
                "name": "Xu Qian",
                "org": "School of Mechanical Electronic and Information Engineering"
            }
        ],
        "title": "Sample data selection method for neural network classifiers",
        "abstract": "In order to improve the performance of neural network classifiers (NNCs), a novel sample data selection method based on shadowed sets was proposed. On the basis of shadowed sets, core data and boundary data were established. First, the optimal fuzzy matrix of sample data was acquired by using FCM. Then, corresponding shadowed sets were induced. On the foundation of sample data and shadowed sets, core data and boundary data could be formed. Finally, the sample data of NNCs could be selected effectively from core data and boundary data. Applying this method and Iris data, experiments for BP neural network, LVQ neural network and extension neural network (ENN) are conducted. Experimental results show that the proposed method can keep typical sample data and reduce the number of training sample data. And with selected sample to train NNCs data can save training time, guarantee generalization ability, and effectively achieve a better performance.",
        "keywords": [
            "Boundary data",
            "Classifiers",
            "Core data",
            "Data selection",
            "Neural networks",
            "Shadowed sets"
        ],
        "venue": "Huazhong Keji Daxue Xuebao (Ziran Kexue Ban)/Journal of Huazhong University of Science and Technology (Natural Science Edition)",
        "year": 2012,
        "id": "OSsbcEaK"
    },
    "BXIxbVYj": {
        "authors": [
            {
                "name": "Yu Zhou",
                "org": "North China Institute of Water Conservancy and Hydroelectric Power"
            },
            {
                "name": "Lin Zhou",
                "org": "Research Institute of Information Technology"
            },
            {
                "name": "Haibin Su",
                "org": "North China Institute of Water Conservancy and Hydroelectric Power"
            }
        ],
        "title": "Enhancing the performance of ENN via data selection technique",
        "abstract": "Training data set is a very important factor mat affects the performance of neural network. In this paper, we use data selection technique based on shadowed sets that can select informative and representative samples for training extension neural network (ENN). The main goal of this paper is to improve the generalization ability and diminish misclassification errors of ENN via training data selection method. Comparative experiments of improved ENN (IENN) and traditional ENN are provided. The experiment results indicate that when the ENN is trained with selected training data, the performance of the ENN improves significantly as opposed to the ENN that does not receive selected input data for training, which verify the effectiveness and applicability of our proposed work. \u00a9 2012 International Information Institute.",
        "keywords": [
            "Data selection",
            "Extension neural network (ENN)",
            "Performance",
            "Training data set"
        ],
        "venue": "Information",
        "year": 2012,
        "id": "BXIxbVYj"
    },
    "9VqZrurI": {
        "authors": [
            {
                "name": "Zhen-Hua Wan",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "De-Jun Sun",
                "org": ""
            }
        ],
        "title": "Numerical investigation of flow-induced oscillations and noise from a rectangular cavity",
        "abstract": "Direct numerical simulation is used to investigate flow-induced oscillations and noise for a low-Reynolds-number subsonic flow over a rectangular cavity with a constant configuration L/D=2. The results indicate that oscillations are dominated by Rossiter II mode in the range of present computational parameters. A low frequency component appears as the decreasing of the thickness of inflow boundary layer, which is directly caused by pattern switching of vortex-edge impingement. The inherent reason is unstable interaction between the recirculation zone and the shear layer. The proper-orthogonal-decomposition (POD) method is employed to analyze the influence of different oscillation pattern on the corresponding vortex structures of the intrinsic mode and its relation with vortex-edge interaction. Moreover, the process of noise generation and propagation is computed and analyzed, and the results are agreed well with available experiments and analytical model.",
        "keywords": [
            "Flow-induced oscillations",
            "Noise",
            "Open cavity flow"
        ],
        "venue": "Kongqi Donglixue Xuebao/Acta Aerodynamica Sinica",
        "year": 2012,
        "id": "9VqZrurI"
    },
    "KV9AaCuj": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Quan Pan",
                "org": ""
            },
            {
                "name": "Yan Liang",
                "org": ""
            }
        ],
        "title": "Estimation method for sensor system error based on Markov stochastic jump system",
        "abstract": "In order to resolve the problem of system error in a Markov stochastic jump system, this paper proposes a novel on-line system error estimation method based on Markov chain Monte Carlo (MCMC) and maximum likelihood. It uses a Metropolis-Hastings sampler to sample from an equitable probability density distributing function which is based on the maximum likelihood estimation. Besides, it can iteratively estimate system error by using expectation maximization (EM) based on the causation of system error estimation and state estimation. The paper simulates two scenes which include time-varying and time-invariant system errors, and the simulations show that this method can take into consideration the system error statistical characteristics, and is feasible and effective in estimating system errors to solve the case of the unknown target state model.",
        "keywords": [
            "Expectation maximization",
            "Markov chain Monte Carlo",
            "Maximum likelihood estimation",
            "Metropolis-Hastings sampling",
            "System error estimaiton"
        ],
        "venue": "Hangkong Xuebao/Acta Aeronautica et Astronautica Sinica",
        "year": 2012,
        "id": "KV9AaCuj"
    },
    "iQfJ2nYf": {
        "authors": [
            {
                "name": "Zheng Yuan",
                "org": ""
            },
            {
                "name": "Yi-Fan Dai",
                "org": ""
            },
            {
                "name": "Xu-Hui Xie",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            }
        ],
        "title": "Ion beam figuring system for ultra-precise optics",
        "abstract": "Ion beam figuring (IBF) is a novel technology for Ultra-precise optics. Material is removed from optic surface in atomic or molecular form by physical sputtering. Due to non-contact between the tool and the work piece, the problems involved in the conventional process are avoided, such as edge-effect and tool-wear. The ion beam figuring process is of high determinacy and high efficiency. All these properties make ion beam figuring one of the promising methods for producing mirrors of high precision with nm-rms accuracy. In this article, a new ion beam figuring system which contains doubled vacuum chambers is set up. Optics can be exchanged by a transport vehicle shuttling between the two vacuum chambers without opening the primary vacuum chamber and waiting for the ion source to cool completely, which means the efficiency can be increased greatly. A high performance processing robot contains three linear axes and two angular axes of motion, providing 5-axis ion source positioning capability with high accuracy. The angle can be up to 50\u00b0 to figure very steep spherical and aspherical surfaces. Then, the beam removal function of Gaussian shape is obtained by an experimental method and it is extremely stable for a long time. Finally, two sample mirrors are figured by the ion beam figuring system: one is a fused silica flat mirror with a 100 mm diameter (90% effective aperture) and an ultra-precise flat mirror with a surface error of 0.89 nm rms, 14.7 nm PV is obtained; the other fused silica concave spherical mirror with a 100 mm aperture (90% effective aperture) and 420 mm radius of curvature is figured and a concave spherical mirror with 1 nm rms, 16.9 nm PV is obtained, which prove that the ion beam figuring system is favourable for the figuring process. \u00a9 (2012) Trans Tech Publications.",
        "keywords": [
            "Beam removal function",
            "Ion beam figuring (IBF) system",
            "Ultra-precise optics"
        ],
        "venue": "Key Engineering Materials",
        "year": 2012,
        "id": "iQfJ2nYf"
    },
    "4GkkIuYO": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Department of Mechanical and Aerospace Engineering"
            },
            {
                "name": "Zhenhua Wan",
                "org": "Department of Modern Mechanics"
            },
            {
                "name": "De-Jun Sun",
                "org": "Department of Modern Mechanics"
            },
            {
                "name": "Mingjun Wei",
                "org": "Department of Mechanical and Aerospace Engineering"
            }
        ],
        "title": "Sound generation by different vortex interactions in mixing layers",
        "abstract": "To understand the correlation between far-field sound and near-field vortex dynamics, in this paper, we numerically investigate the sound generation from different types of vortex interaction (e.g. vortex pairing, vortex tearing, triple/quadruple-vortex merging). Direct numerical simulation (DNS) of the compressible Navier-Stokes equations is carefully conducted for an accurate description of far-field sound radiation. By choosing different phase delays between the fundamental frequency and its sub-harmonics, the vortex interaction changes from perfect pairing to tearing. The sound generated by vortex tearing is much quieter than the one from vortex pairing at the same excitation level. However, the directivity of sound radiations keeps almost the same. When different combinations of forcing frequencies are chosen, there are more complex triple and quadruple vortex mergings, The sound intensity of such cases is stronger than the one of either vortex pairing or vortex tearing. With more frequencies being involved, multi-directivity appears in triple/quadruple-vortex merging cases. \u00a9 2012 by The authors.",
        "keywords": [
            ""
        ],
        "venue": "50th AIAA Aerospace Sciences Meeting Including the New Horizons Forum and Aerospace Exposition",
        "year": 2012,
        "id": "4GkkIuYO"
    },
    "FXDTXBjP": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Fan Wang",
                "org": ""
            },
            {
                "name": "Huotao Gao",
                "org": ""
            },
            {
                "name": "Yuxiang Sun",
                "org": ""
            },
            {
                "name": "Huajun Zhang",
                "org": ""
            }
        ],
        "title": "Design and implementation of equilateral triangle array digital direction finding system",
        "abstract": "In this work, a scheme of an equilateral triangle array digital direction finding system is proposed, which implements the online real-time direction finding task for an airborne system. The three-elements equilateral triangle array can be used for calibrating the channel errors and eliminating the DOA (direction of arrival) fuzzy problem of the two-elements linear array, which is greatly reduced the system complexity and suitable for portable requirement. At the same time, the project adopts field programmable gate array (FPGA) to process the sample data in parallel mode, including data quadrature demodulation and multiple signal classification (MUSIC) algorithm. The hardware implementation of MUSIC algorithm makes the system more flexible and faster than software implementation. The experimental results show that the deviation is less than 0.5 degrees with over 64 snapshots and the time is less 6ms with 256 snapshots, and then the program can complete the MUSIC algorithm accurately with high speed. \u00a9 IEICE 2012.",
        "keywords": [
            "Channel calibration",
            "Direction of arrival",
            "Equilateral triangle array",
            "Field programmable gate array",
            "Multiple signal classification algorithm"
        ],
        "venue": "IEICE Electronics Express",
        "year": 2012,
        "id": "FXDTXBjP"
    },
    "PdbvZjgb": {
        "authors": [
            {
                "name": "Yi Shu",
                "org": "College of Mechanical Engineering and Automation"
            },
            {
                "name": "Lin Zhou",
                "org": "College of Mechanical Engineering and Automation"
            },
            {
                "name": "Xu-Hui Xie",
                "org": "College of Mechanical Engineering and Automation"
            },
            {
                "name": "Wen-Lin Liao",
                "org": "College of Mechanical Engineering and Automation"
            },
            {
                "name": "Sheng-Yi Li",
                "org": "College of Mechanical Engineering and Automation"
            }
        ],
        "title": "Impact of oblique incidence in ion beam figuring on surface roughness",
        "abstract": "Based on the self-developed high-precision and deterministic ion beam figuring (IBF), the paper researched the impact of oblique incidence in IBF on the surface roughness of a typical optical material fused silica. To improve the surface roughness in the polishing process of IBF, two experiments were conducted, one with the polishing at 0\u00b0-80\u00b0 different angles and the other with uniform removal under the oblique incidence angle 45\u00b0. The result of the former experiment shows that surface roughness will not be advanced under perpendicular incidence but can be improved at oblique incidence. At the incidence angle between 30\u00b0-60\u00b0, surface roughness is obviously improved. The result of the latter one shows that RMS of surface roughness is reduced from (0.92\u00b10.06) nm to (0.48\u00b10.04) nm after polishing and that the surface quality of optical parts is improved. Under oblique incidence, the IBF can commendably improve surface roughness and achieve an ultra-smooth surface.",
        "keywords": [
            "Fused silica",
            "Ion beam figuring",
            "Oblique incidence",
            "Surface roughness",
            "Ultra-smooth surface"
        ],
        "venue": "Nami Jishu yu Jingmi Gongcheng/Nanotechnology and Precision Engineering",
        "year": 2012,
        "id": "PdbvZjgb"
    },
    "vVcyyCIm": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Institute of Information Engineering"
            },
            {
                "name": "Xi-Jian Ping",
                "org": "Institute of Information Engineering"
            },
            {
                "name": "Sen Xu",
                "org": "Scholl of Information Engineering"
            },
            {
                "name": "Tao Zhang",
                "org": "Institute of Information Engineering"
            }
        ],
        "title": "Cluster ensemble based on spectral clustering",
        "abstract": "Spectral clustering has become increasingly popular in recent years. It can deal with arbitrary distribution dataset, however, it is sensitive to the scaling parameter. Cluster ensemble based on spectral clustering is proposed which utilizes the good robustness and generalization ability of cluster ensemble. Multiform clustering components are generated by exploiting the property of spectral clustering, and the connected triple algorithm which can expand the similarity information among data is used to compute the affinity matrix, then the affinity matrix is used by spectral clustering algorithm to produce ensemble results. In order to make the algorithm extensible to large scale applications, only the similarity among the rand sampling data and the similarity between the random sampling data and the rest data are computed by adopting the Nystr\u00f6m sampling method. The proposed algorithm makes full use of the excellent performance of spectral clustering as well as avoids the selection of the accurate parameter in spectral clustering. Experiments show that compared with other common cluster ensemble techniques, the proposed algorithm is more excellent and efficient, and that it can provide a good way to solve data clustering and image segmentation problem. Copyright \u00a9 2012 Acta Automatica Sinica. All rights reserved.",
        "keywords": [
            "Cluster ensemble",
            "Connected triple",
            "Image segmentation",
            "Spectral clustering"
        ],
        "venue": "Zidonghua Xuebao/Acta Automatica Sinica",
        "year": 2012,
        "id": "vVcyyCIm"
    },
    "IBQ2JUL1": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Department of Mechanical and Aerospace Engineering"
            },
            {
                "name": "Mingjun Wei",
                "org": "Department of Mechanical and Aerospace Engineering"
            },
            {
                "name": "De-Jun Sun",
                "org": "Department of Modern Mechanics"
            }
        ],
        "title": "A simple model for study of sound generation mechanism in mixing layers",
        "abstract": "Applying Lighthill's acoustic analogy equation to temporally-developing mixing layers, we derived a direct relation between the near-field dynamics, in terms of pressure work, and the farfield sound. The sound radiation predicted by the new model was compared to the direct numerical simulation result, and they agreed well in all stages of vortex dynamics development in mixing layers: roll-up, pairing, merging, saturation, and viscous damping. Using the new formulation, we explained the mechanism for sound generation from the considered flow, and depicted general topological structures for the distribution of sound sources. Though the dynamics is different for vortex roll-up and vortex pairing, the same mechanism for sound generation is suggested by similar topological structures of the sound sources defined here.",
        "keywords": [
            ""
        ],
        "venue": "International Journal of Aeroacoustics",
        "year": 2012,
        "id": "IBQ2JUL1"
    },
    "Ie3kxKxZ": {
        "authors": [
            {
                "name": "Yong Zhao",
                "org": "Shantui Construction Machinery Co., Ltd."
            },
            {
                "name": "Hong Ye",
                "org": "Mechanical Department"
            },
            {
                "name": "Zheng-Sheng Kang",
                "org": "Shantui Construction Machinery Co., Ltd."
            },
            {
                "name": "Song-Shan Shi",
                "org": "Shantui Construction Machinery Co., Ltd."
            },
            {
                "name": "Lin Zhou",
                "org": "Shantui Construction Machinery Co., Ltd."
            }
        ],
        "title": "The recognition of train wheel tread damages based on PSO-RBFNN algorithm",
        "abstract": "In order to the recognition of the train wheel tread damages, the pattern recognition method of the train wheel tread damages based on PSO-RBFNN was developed. The algorithm uses PSO-RBFNN algorithm to optimize center and spread of RBFNN, the connection weight value is sovled by least squares method. Compared with the traditional RBFNN,BP and GA-RBFNN, the experiment results show that the recognition rate of testing samples is higher than the traditional RBFNN, BP and GA-RBFNN, the evolutional generations of PSO-RBFNN algorithm were less than RBFNN, BP and GA-RBFNN. \u00a9 2012 IEEE.",
        "keywords": [
            "PSORBFNN",
            "recognition",
            "train wheel",
            "tread damage"
        ],
        "venue": "Proceedings - International Conference on Natural Computation",
        "year": 2012,
        "id": "Ie3kxKxZ"
    },
    "FgoEmodB": {
        "authors": [
            {
                "name": "Lingling Wang",
                "org": "Key Laboratory of Artificial Materials and Microstructures"
            },
            {
                "name": "Baozhu Lin",
                "org": "Key Laboratory of Artificial Materials and Microstructures"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Artificial Materials and Microstructures"
            },
            {
                "name": "Yan Xia Shang",
                "org": "Key Laboratory of Artificial Materials and Microstructures"
            },
            {
                "name": "Gannidy N. Panin",
                "org": "Institute for Microelectronics Technology"
            },
            {
                "name": "Dejun Fu",
                "org": "Key Laboratory of Artificial Materials and Microstructures"
            }
        ],
        "title": "Nitrogen-doped ZnO nanorods prepared by hydrothermal diffusion",
        "abstract": "ZnO is a wide band-gap material with excellent optical properties for optoelectronics applications. However, device fabrication has been hampered by difficulties in p-type doping. Nitrogen-doped ZnO nanorods were synthesized through thermal diffusion of nitrogen in an aqueous solution at 90 \u00b0C. Low-temperature photoluminescence measured at 10 K showed two peaks located at 3.353 and 3.242 eV, which were assigned to the acceptor-bound excitons and donor-acceptor pairs, respectively. The conductance of the nitrogen-doped ZnO nanorods increased 1.5 times compared with Al-doped samples and 5.8 times compared with undoped ZnO nanorods. The results show hydrothermal process to be an attractive technique for preparation of p-type nitrogen-doped ZnO nanorods. \u00a9 2012 Elsevier B.V. All rights reserved.",
        "keywords": [
            "Crystal growth",
            "Crystal structure",
            "Defects",
            "Diffusion",
            "Luminescence"
        ],
        "venue": "Materials Letters",
        "year": 2012,
        "id": "FgoEmodB"
    },
    "CcLMA5Jr": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "School of Automation"
            },
            {
                "name": "Quan Pan",
                "org": "School of Automation"
            },
            {
                "name": "Yan Liang",
                "org": "School of Automation"
            },
            {
                "name": "Zhenlu Jin",
                "org": "School of Automation"
            }
        ],
        "title": "Joint estimation of state and sensor systematic error in hybrid system",
        "abstract": "Consider the hybrid systems with nonlinear property, and the sensor measurements with unknown and time-varying systematic error in this paper. In order to obtain the joint least square (LS) estimation of state and systematic error, a new method - JE-EM (joint estimation-expectation maximization) is proposed. In this paper, the relationship between the sensor systematic error estimation and state estimation is derived, which can be described by the framework of EM. Due to the character of the hybrid system, the target state is estimated by the IMM with PF filter. Based on the above relationship, systematic error is iteratively estimated by the framework of EM. Simulation results with a maneuvering target tracking scenario show the effectiveness of the proposed method. \u00a9 2012 ISIF (Intl Society of Information Fusi).",
        "keywords": [
            "Expectation maximization (EM)",
            "Hybrid system",
            "Interacting multiple model (IMM)",
            "Particle filter (PF)",
            "Systematic error"
        ],
        "venue": "15th International Conference on Information Fusion, FUSION 2012",
        "year": 2012,
        "id": "CcLMA5Jr"
    },
    "TLaaMbO1": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Fei-Biao Xue",
                "org": ""
            },
            {
                "name": "Fen-Ni Si",
                "org": ""
            },
            {
                "name": "Jian-Lun Yang",
                "org": ""
            },
            {
                "name": "Fan Ye",
                "org": ""
            },
            {
                "name": "Rong-Kun Xu",
                "org": ""
            },
            {
                "name": "Qing-Yuan Hu",
                "org": ""
            },
            {
                "name": "Yue-Cheng Fu",
                "org": ""
            },
            {
                "name": "Shu-Qing Jiang",
                "org": ""
            },
            {
                "name": "Lin-Bo Li",
                "org": ""
            },
            {
                "name": "Jin-Chuan Chen",
                "org": ""
            },
            {
                "name": "Ze-Ping Xu",
                "org": ""
            }
        ],
        "title": "Experimental study of current distribution in wirearray Zpinch plasma",
        "abstract": "The current within imploding multiwire tungsten arrays is measured using micro magnetic probes in the Qiangguang-1 facility at a current of 1.3 MA and rise time of about 70 ns. Difference in current distribution in multiwire arrays between with and without foam cylinder on the array axis is studied. Stable and reliable results are obtained for tungsten wire array Z-pinch with a wire diameter of 4.2 \u03bcm and an annular diameter of 12 mm. The results shows that the output of magnetic probe at a radius of 3.2 mm lags about 20 ns behind the discharge current pulse. After that, the ratio of inside current to the total current increases 20% within 20 ns and keeps steady for 30-40 ns. It is found that the foam cylinder has no appreciable influence on the inside current value in the initial stage of implosioin. \u00a9 2012 Chinese Physical Society.",
        "keywords": [
            "Ablated plasma",
            "Current measurements",
            "Magnetic probe",
            "Wire-array Z-pinch"
        ],
        "venue": "Wuli Xuebao/Acta Physica Sinica",
        "year": 2012,
        "id": "TLaaMbO1"
    },
    "Xz76A4MF": {
        "authors": [
            {
                "name": "Zhen-Hua Wan",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "De-Jun Sun",
                "org": ""
            }
        ],
        "title": "Robustness of the hybrid DRP-WENO scheme for shock flow computations",
        "abstract": "This paper describes a new variant of hybrid scheme that is constructed by a wave-capturing scheme and a nonoscillatory scheme for flow computations in the presence of shocks. The improved fifth-order upwind weighted essentially nonoscillatory scheme is chosen to be conjugated with the seven-point dispersion-relation-preserving scheme by means of an adaptive switch function of grid-point type. The new hybrid scheme can achieve a better resolution than the hybrid scheme which is based on the classical weighted essentially scheme. Ami Harten's multiresolution analysis algorithm is applied to density field for detecting discontinuities and setting point values of the switch function adaptively. Moreover, the tenth-order central filter is applied in smooth part of the flow field for damping dispersion errors. This scheme can promote overall computational efficiency and yield oscillation-free results in shock flows. The resolution properties and robustness of the new hybrid scheme are tested in both 1D and 2D linear and nonlinear cases. It performs well for computing flow problems with rich structures of weak/strong shocks and large/small vortices, such as the shock-boundary layer interaction problem in a shock tube, which illustrates that it is very robust and accurate for direct numerical simulation of gas-dynamics flows. \u00a9 2011 John Wiley & Sons, Ltd.",
        "keywords": [
            "DRP scheme",
            "Filter",
            "Multiresolution analysis",
            "Shock flow computation",
            "The hybrid scheme",
            "WENO-Z scheme"
        ],
        "venue": "International Journal for Numerical Methods in Fluids",
        "year": 2012,
        "id": "Xz76A4MF"
    },
    "XUGmNMXS": {
        "authors": [
            {
                "name": "Yang Wu",
                "org": "Science and Technology on High Power Microwave Laboratory"
            },
            {
                "name": "Zhou Xu",
                "org": "Institute of Applied Electronics"
            },
            {
                "name": "Lin Zhou",
                "org": "Institute of Applied Electronics"
            },
            {
                "name": "Wen-Jun Li",
                "org": "Institute of Applied Electronics"
            },
            {
                "name": "Chuan-Xiang Tang",
                "org": "Department of Engineering Physics"
            }
        ],
        "title": "Simulation and design of a W-band extended interaction klystron amplifier",
        "abstract": "Extended interaction klystron amplifier is a very important high power millimeter wave source with many actual and potential applications. Based on the electromagnetic simulation software and 3D PIC code, a W-band extended interaction klystron amplifier is designed. In the PIC simulation, when the beam voltage is 30 kV and current is 8 A, the device can generate a 43 kW output power at 96.8 GHz with an efficiency of 18% and a gain of 49.3 dB. \u00a9 2012 Chinese Physical Society.",
        "keywords": [
            "Beam-wave interaction",
            "Extended interaction klystron",
            "PIC simulation",
            "W-band"
        ],
        "venue": "Wuli Xuebao/Acta Physica Sinica",
        "year": 2012,
        "id": "XUGmNMXS"
    },
    "pORM9A9Q": {
        "authors": [
            {
                "name": "Zheng Yuan",
                "org": ""
            },
            {
                "name": "Yi-Fan Dai",
                "org": ""
            },
            {
                "name": "Xu-Hui Xie",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            }
        ],
        "title": "Numerical simulation on the thermal deposition of optical surface irradiated by low energy ion beam in ion beam figuring",
        "abstract": "Based on energy deposition theory of Sigmund, the model of thickness of energy perturbation layer caused by low energy ion bombarding optical surface is built up. Beam current density on the optical surface is obtained by theory analysis, and the model of thermal deposition caused by low energy ion bombarding optical surface is built up. TRIM program is used to simulate the collision between low energy ions and atoms on the optical surface. And then, contributions to the thermal deposition and energy perturbation layer thickness from parameters such as ion energy, ion type and incidence angle are discussed. Finally, by taking the thermal quantity of deposited workpiece as a heat source in ANSYS, temperature field, thermal gradient field and stress field of the workpiece are obtained. The temperature and thermal gradient of the surface radiated by ion beam each present a Gaussian profile, and decrease along the radius from the center to the edge. The stress on the surface is a compressive stress within the radius of Half Maxim, and it is a tension-tension stress from the radius of Half Maxim to the edge. \u00a9 2012 Chinese Physical Society.",
        "keywords": [
            "Ion beam figuring (IBF)",
            "Optical fabrication",
            "Thermal deposition",
            "Thermal field"
        ],
        "venue": "Wuli Xuebao/Acta Physica Sinica",
        "year": 2012,
        "id": "pORM9A9Q"
    },
    "j3G64sMX": {
        "authors": [
            {
                "name": "Xiusheng Chen",
                "org": "School of Mechanical Engineering"
            },
            {
                "name": "Gang Xu",
                "org": "Potdoctoral Workstation"
            },
            {
                "name": "Anlin Wang",
                "org": "School of Mechanical Engineering"
            },
            {
                "name": "Aizhen Yao",
                "org": "Potdoctoral Workstation"
            },
            {
                "name": "Lin Zhou",
                "org": "Potdoctoral Workstation"
            },
            {
                "name": "Chun Peng",
                "org": "Potdoctoral Workstation"
            },
            {
                "name": "Cunbo Liu",
                "org": "Potdoctoral Workstation"
            }
        ],
        "title": "Design of bulldozer's remote monitoring service system based on GPS",
        "abstract": "In this paper, functions of bulldozer's remote monitoring service system are analyzed. Construction of the monitoring service system is proposed. Key parts of the system such as data server, backup database server, GPS monitor terminal, user interface are developed. As a result, the bulldozer's remote monitoring service system based on GPS is of great useful for remote monitoring and control of bulldozer. \u00a9 (2012) Trans Tech Publications, Switzerland.",
        "keywords": [
            "Bulldozer",
            "GPS monitor terminal",
            "Remote monitoring"
        ],
        "venue": "Advanced Materials Research",
        "year": 2012,
        "id": "j3G64sMX"
    },
    "0BV09hjS": {
        "authors": [
            {
                "name": "Xiao-Xue Feng",
                "org": "Northwestern Polytechnical University"
            },
            {
                "name": "Yan Liang",
                "org": "Northwestern Polytechnical University"
            },
            {
                "name": "Lin Zhou",
                "org": "Northwestern Polytechnical University"
            },
            {
                "name": "Lian-Meng Jiao",
                "org": "Northwestern Polytechnical University"
            }
        ],
        "title": "Coordinate transformation for OTHR with target height",
        "abstract": "The complicated nonlinear coordinate transformation commonly used in the over the horizon radar (OTHR) is not accurate for ignorance of the target height. In this paper, a novel OTHR measurement model considering the target height is proposed, and the detailed coordinate transformation formula between radar coordinates and ground coordinates is deduced. The simulation results of state estimate with and without target height show that the measurement model considering the target height can greatly decrease the state estimate error. The proposed method can effectively reduce the system bias caused by coordinate transformation, so as to improve tracking accuracy. \u00a9 2012 Chinese Assoc of Automati.",
        "keywords": [
            "Coordinate transformation",
            "Over the horizon Radar",
            "Target height"
        ],
        "venue": "Chinese Control Conference, CCC",
        "year": 2012,
        "id": "0BV09hjS"
    },
    "OUQ7HgD9": {
        "authors": [
            {
                "name": "Yong Zhao",
                "org": "Shantui Construction Machinery Co., Ltd."
            },
            {
                "name": "Hong Ye",
                "org": "Key Laboratory of Highway Construction Technology and Equipment of Ministry of Education"
            },
            {
                "name": "Yong-Biao Hu",
                "org": "Key Laboratory of Highway Construction Technology and Equipment of Ministry of Education"
            },
            {
                "name": "Song-Shan Shi",
                "org": "Shantui Construction Machinery Co., Ltd."
            },
            {
                "name": "Lin Zhou",
                "org": "Shantui Construction Machinery Co., Ltd."
            }
        ],
        "title": "Research on burning dynamic inspection technology of wheel tread using vision",
        "abstract": "In order to realize burning inspection for the train wheel tread, a burning dynamic inspecting technology using vision were investigated. Firstly, the tread region was segmented by tread segmentation technology based on improved Canny algorithm combined stationary wavelet edge detection algorithm. Then the extracting technologies of the suspicious regions of the wheel tread burnings based on tread boundary searching technology are studied. Finally, GA-BP algorithm was applied in the pattern recognition of burnings based on the feature extraction. The experimental results show that that the burning effective detecion was 96.67%, the fulfillment rate was 65.7%.Therefore, the proposed method was effective method of burning dynamic inspection. \u00a9 2012 IEEE.",
        "keywords": [
            "Burning",
            "Dynamic inspection",
            "vision",
            "wheel tread"
        ],
        "venue": "Proceedings - 2012 9th International Conference on Fuzzy Systems and Knowledge Discovery, FSKD 2012",
        "year": 2012,
        "id": "OUQ7HgD9"
    },
    "i81CZTJt": {
        "authors": [
            {
                "name": "Xiaowei Zhang",
                "org": "School of Information Science and Engineering"
            },
            {
                "name": "Daniel Cao",
                "org": "School of Information Science and Engineering"
            },
            {
                "name": "Philip Moore",
                "org": "School of Computing, Telecommunications and Networks"
            },
            {
                "name": "Jing Chen",
                "org": "School of Information Science and Engineering"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Information Science and Engineering"
            },
            {
                "name": "Yang Zhou",
                "org": "School of Information Science and Engineering"
            },
            {
                "name": "Xu Ma",
                "org": "School of Information Science and Engineering"
            }
        ],
        "title": "A Bayesian Network (BN) based probabilistic solution to enhance emotional ontology",
        "abstract": "Recognizing an emotional context created using human bio-signals has gained traction in contemporary applications. The current emotional ontology however cannot handle probabilistic information in the emotion recognition process. The primary goal of this research is to utilize a Bayesian Network into the study of EEG-based emotion recognition to address the probabilistic context data. The work is based our previous emotion ontology prototype 'Emotiono'; the EEG dataset for evaluating its performance being extracted from 'DEAP' which an open multimodal database for emotion analysis. With 10-fold data in validation the average classification rate using the posited method reaches 86.8 % for Arousal and 85.9 % for Valence in the two dimensional emotion recognition processes. \u00a9 2012 Springer Science+Business Media.",
        "keywords": [
            "Bayesian Networks",
            "emotion",
            "emotion recognition",
            "Ontology"
        ],
        "venue": "Lecture Notes in Electrical Engineering",
        "year": 2012,
        "id": "i81CZTJt"
    },
    "5DR2Mmoz": {
        "authors": [
            {
                "name": "Yong Zhao",
                "org": "Shantui Construction Machinery Co., Ltd"
            },
            {
                "name": "Lin Zhou",
                "org": "Shantui Construction Machinery Co., Ltd"
            }
        ],
        "title": "Parameter matching theory of hybrid track-type bulldozer power system",
        "abstract": "In order to improve the efficiency of hybrid power system of hybrid track-type bulldozers, The hybrid track-type bulldozer structure was established and parameter matchiing theory of hybrid power system was investigated. The parameters of the main components, such as the traction motor, engine, generator and capacitor of ultracapacitor were matched by using the method. The matching results were analyzed based on hybrid track-type bulldozer model. The results show that the efficiency of hybrid track-type bulldozer was increased by 20%. \u00a9 2012 TSI Press.",
        "keywords": [
            "bulldozer",
            "hybrid",
            "matching theory",
            "power system"
        ],
        "venue": "World Automation Congress Proceedings",
        "year": 2012,
        "id": "5DR2Mmoz"
    },
    "dMKhzdOD": {
        "authors": [
            {
                "name": "Yong Zhao",
                "org": ""
            },
            {
                "name": "Yong Biao Hu",
                "org": ""
            },
            {
                "name": "Songshan Shi",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Hong Ye",
                "org": ""
            }
        ],
        "title": "Motor parameter matching method of hybrid track-type bulldozer",
        "abstract": "In order to decrease fuel consumption and improve efficiency, the hybrid system of hybrid track-type bulldozer is established and its motor parameter matching method is investigated. According to traction dynamics theory of the track-type bulldozer, motor rated power, motor rated speed, motor peaking power, motor speed and maximum torque are calculated. The results show that motor parameter matching method is correct. It can provide theory basis for motor design of hybrid track-type bulldozer. \u00a9 2012 TSI Press.",
        "keywords": [
            "hybrid power",
            "motor paramete",
            "track-type bulldozer"
        ],
        "venue": "World Automation Congress Proceedings",
        "year": 2012,
        "id": "dMKhzdOD"
    },
    "QWtxJBrc": {
        "authors": [
            {
                "name": "Yong Lu",
                "org": "College of Computer and Information Engineering"
            },
            {
                "name": "Zongyu Xu",
                "org": "College of Computer and Information Engineering"
            },
            {
                "name": "Qin Yan",
                "org": "College of Computer and Information Engineering"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Information Science and Engineering"
            }
        ],
        "title": "Model adaptation based on improved variance estimation for robust speech recognition",
        "abstract": "This paper proposes a model adaptation algorithm based on improved variance estimation for noise robust speech recognition. In this algorithm, the approximate closed-form variance estimation is extended from the feature space to the model space and the dynamic parameters of the hidden Markov model (HMM) as well as the static parameters are converted to testing conditions. The experimental results show that the proposed model adaptation algorithm can converge quickly and outperforms the feature compensation method using the approximate closed-form variance estimation. \u00a9 2012 IEEE.",
        "keywords": [
            "model adaptation",
            "speech recognition",
            "variance estimation",
            "vector Taylor series"
        ],
        "venue": "2012 International Conference on Wireless Communications and Signal Processing, WCSP 2012",
        "year": 2012,
        "id": "QWtxJBrc"
    },
    "NAKo2vG9": {
        "authors": [
            {
                "name": "Haiyang Wu",
                "org": "School of Information Science and Engineering"
            },
            {
                "name": "Feiran Yang",
                "org": "Key Laboratory of Noise and Vibration Research"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Information Science and Engineering"
            },
            {
                "name": "Zhenyang Wu",
                "org": "School of Information Science and Engineering"
            }
        ],
        "title": "Feature compensation algorithm based on vector Taylor series for speaker recognition",
        "abstract": "A feature compensation algorithm based on vector Taylor series (VTS) is applied to the speaker recognition system. The approximate closed-form solution of the channel variance is derived, and a joint rapid estimation framework for convolution noise and additive noise is proposed. The mean and variance of convolution noise and additive noise can be estimated from the mismatch speech to compensate the environment mismatch without any other prior information about the mismatch environment. The experimental results show that the compensation of the channel variance maximally reduces the error rate by 3.24%, which improve the system performance in the wireless environment with large channel variations. Compared with feature mapping algorithm and cepstrum mean subtraction algorithm based on the linear distortion model, the proposed algorithm decreases the system error rate by 49.65% and 68.06% at maximum in the wireless environment with additional noise, respectively, especially for the mismatch environment of large channel variations.",
        "keywords": [
            ""
        ],
        "venue": "Shengxue Xuebao/Acta Acustica",
        "year": 2013,
        "id": "NAKo2vG9"
    },
    "6WqhKA7v": {
        "authors": [
            {
                "name": "Chenghua Wang",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Feng Jiang",
                "org": ""
            },
            {
                "name": "Hongbo Zhao",
                "org": ""
            }
        ],
        "title": "A granular computing based decision tree algorithm and its application in intrusion detection",
        "abstract": "Decision tree algorithms have been widely used in intrusion detection. In this paper, within the framework of granular computing (GrC), we propose a new decision tree algorithm called DTGAE and apply it to intrusion detection. First, by virtue of the GrC model using information tables, we propose a new information entropy model, which contains two basic notions: approximation entropy of granule (AEG) and GrC-based approximation entropy (GAE), where the latter is defined based on the former. In algorithm DTGAE, GAE is adopted as the heuristic information for the selection of splitting attributes. When calculating AEG and GAE, we not only utilize the concept of conditional entropy in Shannon's information theory, but also use the concept of approximation accuracy in rough sets. Second, we present a method of decision tree pre-pruning based on Duntsch's knowledge entropy. Finally, the KDDCUP99 data set is used to verify the effectiveness of our algorithm in intrusion detection. \u00a9 (2013) Trans Tech Publications, Switzerland.",
        "keywords": [
            "Approximation accuracy",
            "Decision tree",
            "Granular computing",
            "Intrusion detection",
            "Rough sets"
        ],
        "venue": "Applied Mechanics and Materials",
        "year": 2013,
        "id": "6WqhKA7v"
    },
    "lUkv0oG8": {
        "authors": [
            {
                "name": "Wenlin Liao",
                "org": "College of Mechatronics and Automation, National University of Defense Technology"
            },
            {
                "name": "Yifan Dai",
                "org": "College of Mechatronics and Automation, National University of Defense Technology"
            },
            {
                "name": "Xuhui Xie",
                "org": "College of Mechatronics and Automation, National University of Defense Technology"
            },
            {
                "name": "Lin Zhou",
                "org": "College of Mechatronics and Automation, National University of Defense Technology"
            }
        ],
        "title": "Deterministic ion beam material adding technology for high-precision optical surfaces",
        "abstract": "Although ion beam figuring (IBF) provides a highly deterministic method for the precision figuring of optical components, several problems still need to be addressed, such as the limited correcting capability for mid-to-high spatial frequency surface errors and low machining efficiency for pit defects on surfaces. We propose a figuring method named deterministic ion beam material adding (IBA) technology to solve those problems in IBF. The current deterministic optical figuring mechanism, which is dedicated to removing local protuberances on optical surfaces, is enriched and developed by the IBA technology. Compared with IBF, this method can realize the uniform convergence of surface errors, where the particle transferring effect generated in the IBA process can effectively correct the mid-to-high spatial frequency errors. In addition, IBA can rapidly correct the pit defects on the surface and greatly improve the machining efficiency of the figuring process. The verification experiments are accomplished on our experimental installation to validate the feasibility of the IBA method. First, a fused silica sample with a rectangular pit defect is figured by using IBA. Through two iterations within only 47.5 min, this highly steep pit is effectively corrected, and the surface error is improved from the original 24.69 nm root mean square (RMS) to the final 3.68 nm RMS. Then another experiment is carried out to demonstrate the correcting capability of IBA for mid-to-high spatial frequency surface errors, and the final results indicate that the surface accuracy and surface quality can be simultaneously improved. \u00a9 2013 Optical Society of America.",
        "keywords": [
            ""
        ],
        "venue": "Applied Optics",
        "year": 2013,
        "id": "lUkv0oG8"
    },
    "cRuh9EEs": {
        "authors": [
            {
                "name": "Fa-Xin Chen",
                "org": "Institute of Nuclear Physics and Chemistry"
            },
            {
                "name": "Jing-Hua Feng",
                "org": "Institute of Nuclear Physics and Chemistry"
            },
            {
                "name": "Lin-Bo Li",
                "org": "Institute of Nuclear Physics and Chemistry"
            },
            {
                "name": "Jian-Lun Yang",
                "org": "Institute of Nuclear Physics and Chemistry"
            },
            {
                "name": "Lin Zhou",
                "org": "Institute of Nuclear Physics and Chemistry"
            },
            {
                "name": "Rong-Kun Xu",
                "org": "Institute of Nuclear Physics and Chemistry"
            },
            {
                "name": "Ze-Ping Xu",
                "org": "Institute of Nuclear Physics and Chemistry"
            }
        ],
        "title": "Study of Z-pinch dynamic hohlraum shadowgraphy",
        "abstract": "In order to obtain the dynamic evolution image of tungsten array for foam padding, and to research the form of interaction between tungsten plasma and foam column, a shadow imaging system of four-frame ultraviolet probe laser (266 nm) is designed on 1 MA pulse power device. The time resolution of the system is 2.5 ns, and static space resolution is superior to 70 \u03bcm. The radial shadowgraphy image reveals the whole process from the melting and expansion of solid wire to the interaction between the precursor plasma and the foam, from the pinch to rebound inflation. The image shows the continuous interaction between tungsten plasma and foam in the form of \"Raining\" within a time of about 50 ns, the plasma shell structure is not found in the whole period of pinch. The quantitative analysis indicates that the minimum pinching speed of the foam column is 1.0\u00d710",
        "keywords": [
            "Dynomic hohlraum",
            "Pinching speed",
            "Shadowgram"
        ],
        "venue": "Wuli Xuebao/Acta Physica Sinica",
        "year": 2013,
        "id": "cRuh9EEs"
    },
    "at4rZKB8": {
        "authors": [
            {
                "name": "Xiaowei Zhang",
                "org": ""
            },
            {
                "name": "Bin Hu",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Philip Moore",
                "org": ""
            },
            {
                "name": "Jing Chen",
                "org": ""
            }
        ],
        "title": "An EEG based pervasive depression detection for females",
        "abstract": "Recently, depression detection is mainly completed by some rating scales. This procedure requires attendance of physicians and the results may be more subjective. To meet emergent needs of objective and pervasive depression detection, we propose an EEG based approach for females. In the experiment, EEG of 13 depressed females and 12 age matched controls were collected in a resting state with eyes closed. Linear and nonlinear features extracted from artifact-free EEG epochs were subjected to statistical analysis to examine the significance of differences. Results showed that differences were significant for some EEG features between two groups (p<0.05) and the classification rates reached up to 92.9% and 94.2% with KNN and BPNN respectively. Our methods suggest that the discrimination of depressed females from controls is possible. We expect that our EEG based approach could be a pervasive assistant diagnosis tool for psychiatrists and health care specialists. \u00a9 2013 Springer-Verlag.",
        "keywords": [
            "Depression",
            "EEG",
            "Pervasive computing"
        ],
        "venue": "Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)",
        "year": 2013,
        "id": "at4rZKB8"
    },
    "7FXH6jDy": {
        "authors": [
            {
                "name": "Xiaoyan Zhao",
                "org": "Key Laboratory of Underwater Acoustic Signal Processing of Ministry of Education"
            },
            {
                "name": "Jie Tang",
                "org": "Key Laboratory of Underwater Acoustic Signal Processing of Ministry of Education"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Underwater Acoustic Signal Processing of Ministry of Education"
            },
            {
                "name": "Zhenyang Wu",
                "org": "Key Laboratory of Underwater Acoustic Signal Processing of Ministry of Education"
            }
        ],
        "title": "Multiple sound source localization of microphones based on complex exponential transform of phase differences",
        "abstract": "To improve the performance of multiple sound source localization and avoid the phase-unwrapping process at high frequencies, a localization algorithm for multiple sound sources of two microphones based on complex exponential transform of phase differences is proposed. First, the reliable frequency points with high signal-to-noise are selected to enhance the robustness of the proposed method against noise. The inter-channel phase differences (IPDs) of the selected frequency points are converted with complex exponential transform. Then, the selected frequency points are clustered into groups corresponding to multiple sources based on speech's sparse attribute in time-frequency domain. Finally, the assumed time-delay difference which minimizes the cost function building on the frequency points of each source is the estimated time-delay difference of the source. The simulation results show that the proposed algorithm takes full advantage of the high-frequency phase information without phase-unwrapping process for IPDs at high frequencies. Compared with the generalized hard clustering algorithm (GHCA), the proposed algorithm has a faster convergence speed, and obtains a higher percentage of successful estimates and a lower root mean square error.",
        "keywords": [
            "Complex exponential transform",
            "Phase differences",
            "Phase wrapping",
            "Sound source localization",
            "Sparsity"
        ],
        "venue": "Dongnan Daxue Xuebao (Ziran Kexue Ban)/Journal of Southeast University (Natural Science Edition)",
        "year": 2013,
        "id": "7FXH6jDy"
    },
    "pkjfh0hs": {
        "authors": [
            {
                "name": "Zheng Yuan",
                "org": "College of Mechatronics and Automation"
            },
            {
                "name": "Yi-Fan Dai",
                "org": "College of Mechatronics and Automation"
            },
            {
                "name": "Xu-Hui Xie",
                "org": "College of Mechatronics and Automation"
            },
            {
                "name": "Lin Zhou",
                "org": "College of Mechatronics and Automation"
            },
            {
                "name": "Chao-Liang Guan",
                "org": "College of Mechatronics and Automation"
            },
            {
                "name": "Shu-Rui Feng",
                "org": "College of Mechatronics and Automation"
            }
        ],
        "title": "Cleaning of iron powders embedded into the surface of KDP crystal by ion beam figuring",
        "abstract": "Magnetorheological figuring (MRF) is one of the ultra-precise machining methods for KDP crystal, but iron powders from magnetorheological fluid are easy embedding into the soft KDP crystal. In order to remove these iron powders, ion beam figuring (IBF) based on low energy ion sputtering was put forward to bombard KDP surface polished by MRF. The changes of crystal structures and surface roughness of KDP before and after IBF were analyzed by Raman spectral analysis technology and white light interferometer, respectively. Moreover, surface elements of KDP crystal machined by MRF, IBF were researched through secondary ion mass spectroscopy (SIMS) analysis. The results indicated that crystal structure is not changed and the roughness is improved by low energy ion sputtering, which means that IBF could be used for machining KDP crystal. After IBF the iron powders on the surface of KDP crystal are cleaned on the whole.",
        "keywords": [
            "Ion beam figuring (IBF)",
            "Iron powders removing",
            "KDP crystal",
            "Magnetorheological figuring (MRF)"
        ],
        "venue": "Rengong Jingti Xuebao/Journal of Synthetic Crystals",
        "year": 2013,
        "id": "pkjfh0hs"
    },
    "uJsQs0Yk": {
        "authors": [
            {
                "name": "Wenlin Liao",
                "org": "College of Mechatronics and Automation, National University of Defense Technology"
            },
            {
                "name": "Yifan Dai",
                "org": "College of Mechatronics and Automation, National University of Defense Technology"
            },
            {
                "name": "Xuhui Xie",
                "org": "College of Mechatronics and Automation, National University of Defense Technology"
            },
            {
                "name": "Lin Zhou",
                "org": "College of Mechatronics and Automation, National University of Defense Technology"
            }
        ],
        "title": "Morphology evolution of fused silica surface during ion beam figuring of high-slope optical components",
        "abstract": "Ultra-precision and ultra-smooth surfaces are vitally important for some high performance optical systems. Ion beam figuring (IBF) is a well-established, highly deterministic method for the final precision figuring of extremely high quality optical surfaces, whereas ion sputtering induced smoothing, or roughening for nanoscale surface morphology, strongly depends on the processing conditions. Usually, an improper machining method would arouse the production of nanoscale patterns leading to the coarsening of the optical surface. In this paper, the morphology evolution mechanism on a fused silica surface during IBF of high-slope optical components has been investigated by means of atomic force microscopy. Figuring experiments are implemented on two convex spherical surfaces by using different IBF methods. Both of their surface errors are rapidly reduced to 1.2 nm root mean square (RMS) after removing similar deep material, but their surfaces are characterized with obviously different nanoscale morphologies. The experimental results indicate that the ion incidence angle dominates the microscopic morphology during the IBF process. At near-normal incidence, fused silica achieves an ultra-smooth surface with an RMS roughness value R<inf>q</inf> down to 0.1 nm, whereas nanoscale ripple patterns are observed at a large incidence angle with an R<inf>q</inf> value increasing to more than 0.9 nm. Additionally, the difference of incidence angles on various machined areas would influence the uniformity of surface quality, resulting from the interplay between the smoothing and roughening effects induced by ion sputtering. \u00a9 2013 Optical Society of America.",
        "keywords": [
            ""
        ],
        "venue": "Applied Optics",
        "year": 2013,
        "id": "uJsQs0Yk"
    },
    "Lc3n7JG7": {
        "authors": [
            {
                "name": "Wenlin Liao",
                "org": "National University of Defense Technology"
            },
            {
                "name": "Yifan Dai",
                "org": "National University of Defense Technology"
            },
            {
                "name": "Xuhui Xie",
                "org": "National University of Defense Technology"
            },
            {
                "name": "Lin Zhou",
                "org": "National University of Defense Technology"
            }
        ],
        "title": "Combined figuring technology for high-precision optical surfaces using a deterministic ion beam material adding and removal method",
        "abstract": "We propose a deterministic figuring method for fabricating high-precision optical surfaces by combining ion beam material adding (IBA) and material removal [ion beam figuring (IBF)] technology. The IBA is first utilized to improve the accuracy and quality of the optical surface by deterministically adding material to the local pits, and then the IBF is applied to further improve the surface accuracy through removing the local protuberances. Compared with current IBF technology, this combined method can realize the uniform convergence of the surface errors and simultaneously increase the convergence rate of the figuring process. \u00a9 2013 Society of Photo-Optical Instrumentation Engineers (SPIE).",
        "keywords": [
            ""
        ],
        "venue": "Optical Engineering",
        "year": 2013,
        "id": "Lc3n7JG7"
    },
    "ffjlG3wT": {
        "authors": [
            {
                "name": "Xiaoyan Zhao",
                "org": ""
            },
            {
                "name": "Jie Tang",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Zhenyang Wu",
                "org": ""
            }
        ],
        "title": "Accelerated steered response power method for sound source localization via clustering search",
        "abstract": "The steered response power-phase transform (SRP-PHAT) sound source localization algorithm is robust in a real environment. However, the large computation complexity limits the practical application of SRP-PHAT. For a microphone array, each location corresponds to a set of time differences of arrival (TDOAs), and this paper collects them into a TDOA vector. Since the TDOA vectors in the adjacent regions are similar, we present a fast algorithm based on clustering search to reduce the computation complexity of SRP-PHAT. In the training stage, the K-means or Iterative Self-Organizing Data Analysis Technique (ISODATA) clustering algorithm is used to find the centroid in each cluster with similar TDOA vectors. In the procedure of sound localization, the optimal cluster is found by comparing the steered response powers (SRPs) of all centroids. The SRPs of all candidate locations in the optimal cluster are compared to localize the sound source. Experiments both in simulation environments and real environments have been performed to compare the localization accuracy and computational load of the proposed method with those of the conventional SRP-PHAT algorithm. The results show that the proposed method is able to reduce the computational load drastically and maintains almost the same localization accuracy and robustness as those of the conventional SRP-PHAT algorithm. The difference in localization performance brought by different clustering algorithms used in the training stage is trivial. \u00a9 2013 Science China Press and Springer-Verlag Berlin Heidelberg.",
        "keywords": [
            "clustering search",
            "microphone array",
            "sound source localization",
            "steered response power"
        ],
        "venue": "Science China: Physics, Mechanics and Astronomy",
        "year": 2013,
        "id": "ffjlG3wT"
    },
    "YZNA2bKr": {
        "authors": [
            {
                "name": "Shu-Qing Jiang",
                "org": "Institute of Nuclear Physics and Chemistry"
            },
            {
                "name": "Jia-Min Ning",
                "org": "Institute of Nuclear Physics and Chemistry"
            },
            {
                "name": "Fa-Xin Chen",
                "org": "Institute of Nuclear Physics and Chemistry"
            },
            {
                "name": "Fan Ye",
                "org": "Institute of Nuclear Physics and Chemistry"
            },
            {
                "name": "Fei-Biao Xue",
                "org": "Institute of Nuclear Physics and Chemistry"
            },
            {
                "name": "Lin-Bo Li",
                "org": "Institute of Nuclear Physics and Chemistry"
            },
            {
                "name": "Jian-Lun Yang",
                "org": "Institute of Nuclear Physics and Chemistry"
            },
            {
                "name": "Jin-Chuan Chen",
                "org": "Institute of Nuclear Physics and Chemistry"
            },
            {
                "name": "Lin Zhou",
                "org": "Institute of Nuclear Physics and Chemistry"
            },
            {
                "name": "Yi Qin",
                "org": "Institute of Nuclear Physics and Chemistry"
            },
            {
                "name": "Zheng-Hong Li",
                "org": "Institute of Nuclear Physics and Chemistry"
            },
            {
                "name": "Rong-Kun Xu",
                "org": "Institute of Nuclear Physics and Chemistry"
            },
            {
                "name": "Ze-Ping Xu",
                "org": "Institute of Nuclear Physics and Chemistry"
            }
        ],
        "title": "Preliminary experimental study on implosion dynamics and radiation character of Z-pinch dynamic hohlraum",
        "abstract": "The Z-pinch dynamic hohlraum (ZPDH), as implemented on qiangguang-1 facility at NINT, is composed of an annular tungsten plasma that implodes onto a coaxial foam convertor. The collision between tungsten Z pinch and foam convertor launches a strong shock. The shock generates a strong radiation pulse, referred as the first radiation power peak, then the radiation is trapped by the tungsten Z pinch. As pinch diameter decreases, the second radiation power pulse rises and acts as the main power peak. The radiation and dynamic characteristics do not show obvious difference between the 8 mm and 12 mm wire array configurations. Hence, it is important to notice that the foam reduces the influence of global instability generated byMRT instability on stagnated pinch, especially reduces the growth of m = 0 and m = 1 MHD instability. \u00a9 Chinese Physical Society.",
        "keywords": [
            "Foam hohlraum",
            "Implosion dynamics",
            "Radiation character",
            "ZPDH"
        ],
        "venue": "Wuli Xuebao/Acta Physica Sinica",
        "year": 2013,
        "id": "YZNA2bKr"
    },
    "88TRdySz": {
        "authors": [
            {
                "name": "Zheng Yuan",
                "org": "School of Mechatronic Engineering and Automation"
            },
            {
                "name": "Yifan Dai",
                "org": "School of Mechatronic Engineering and Automation"
            },
            {
                "name": "Xuhui Xie",
                "org": "School of Mechatronic Engineering and Automation"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Mechatronic Engineering and Automation"
            },
            {
                "name": "Wenqiang Peng",
                "org": "School of Mechatronic Engineering and Automation"
            }
        ],
        "title": "Research on ultra-precise figuring for CaF2 single crystal",
        "abstract": "In order to machine ultra-precise and extremely smooth calcium fluoride (CaF",
        "keywords": [
            "Calcium fluoride",
            "Optical fabrication",
            "Surface roughness"
        ],
        "venue": "Jixie Gongcheng Xuebao/Journal of Mechanical Engineering",
        "year": 2013,
        "id": "88TRdySz"
    },
    "zSeTB7bM": {
        "authors": [
            {
                "name": "Qing Chen Zhou",
                "org": "Electromagnetic Wave and Modern Radar Lab"
            },
            {
                "name": "Huo Tao Gao",
                "org": "Electromagnetic Wave and Modern Radar Lab"
            },
            {
                "name": "Hua Jun Zhang",
                "org": "Electromagnetic Wave and Modern Radar Lab"
            },
            {
                "name": "Lin Zhou",
                "org": "Electromagnetic Wave and Modern Radar Lab"
            }
        ],
        "title": "Superdirective beamforming with interferences and noise suppression via second-order cone programming",
        "abstract": "Based on second-order cone programming, we present a new superdirective beamforming method with interferences and noise suppression for small aperture HF receive arrays. In the novel method, low side lobe level (SLL) and nulls are not only used to suppress interferences and noise, but also play an important part in overcoming the low array efficiency brought by superdirective beamforming. According to the actual condition, the new method can present a good tradeoff between directive gain, array efficiency, SLL, nulls and robustness against array uncertainty. Compared with the existing methods, it is more effective in suppressing interference and noise. The superiority and validity of the proposed method can be illustrated by numerical results.",
        "keywords": [
            ""
        ],
        "venue": "Progress In Electromagnetics Research C",
        "year": 2013,
        "id": "zSeTB7bM"
    },
    "3Vyu4QzR": {
        "authors": [
            {
                "name": "Fan Ye",
                "org": "Institute of Nuclear Physics and Chemistry"
            },
            {
                "name": "Fei-Biao Xue",
                "org": "Institute of Nuclear Physics and Chemistry"
            },
            {
                "name": "Yan-Yun Chu",
                "org": "Institute of Nuclear Physics and Chemistry"
            },
            {
                "name": "Fen-Ni Si",
                "org": "Institute of Nuclear Physics and Chemistry"
            },
            {
                "name": "Qing-Yuan Hu",
                "org": "Institute of Nuclear Physics and Chemistry"
            },
            {
                "name": "Jia-Min Ning",
                "org": "Institute of Nuclear Physics and Chemistry"
            },
            {
                "name": "Lin Zhou",
                "org": "Institute of Nuclear Physics and Chemistry"
            },
            {
                "name": "Jian-Lun Yang",
                "org": "Institute of Nuclear Physics and Chemistry"
            },
            {
                "name": "Rong-Kun Xu",
                "org": "Institute of Nuclear Physics and Chemistry"
            },
            {
                "name": "Zheng-Hong Li",
                "org": "Institute of Nuclear Physics and Chemistry"
            },
            {
                "name": "Ze-Ping Xu",
                "org": "Institute of Nuclear Physics and Chemistry"
            }
        ],
        "title": "Experimental study on current division of nested wire array Z pinches",
        "abstract": "The current division between the inner and the outer arrays is one of the key factors that impact the implosion dynamics and modes of nested wire array. This paper presents the first quantitative measurements of current division for nested wire array Z pinch on the Qiang Guang-I pulsed power facility. In experiments, the nested wire arrays, made of 3.8 \u03bcm-diameter tungsten wires, were 20 mm in height and 8 mm/16 mm in diameter for inner/outer array. Measurements for loads consisting of 42/21 wires in inner/outer array were compared with that of 21/42 in inner/outer array. Data of current versus time at various radial positions were obtained using magnetic probes until 20 ns before the current peak. Results show that the currents in inner and outer arrays increase during the rise of the driving current, the proportion of current in outer array decreases and that in inner array increases, while the current in outer array, for loads with 21/42 wires in inner/outer array, was larger than those with 42/21 wires in inner/outer array. \u00a9 2013 Chinese Physical Society.",
        "keywords": [
            "Current division",
            "Nested wire array",
            "Z pinch"
        ],
        "venue": "Wuli Xuebao/Acta Physica Sinica",
        "year": 2013,
        "id": "3Vyu4QzR"
    },
    "h0wpFOQT": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "College of Computer and Information Engineering, Henan University"
            },
            {
                "name": "Quan Pan",
                "org": "School of Automation, Northwestern Polytechnical University"
            },
            {
                "name": "Yan Liang",
                "org": "School of Automation, Northwestern Polytechnical University"
            },
            {
                "name": "Chao Guan",
                "org": "School of Automation, Northwestern Polytechnical University"
            }
        ],
        "title": "Systematic biases estimation method based on combined PSO and PDA",
        "abstract": "In clutter background, in order to solve some problems including measurements echoes and systematic biases randomization, a new on-line systematic biases estimation method is proposed under dense clutters. Firstly, the association probabilities of measurements echoes are obtained by PDA method. Then, the objective function of optimization is constructed using association probabilities. Finally, the systematic biases are estimated by PSO optimization operation. The proposed algorithm considers the variety of systematic biases particles of PSO and measurements echoes of PDA, synthetically. Simulation results show that the proposed algorithm is a good method for systematic biases estimation in clutters. \u00a9 2013 TCCT, CAA.",
        "keywords": [
            "Biases Estimation",
            "Particle Swarm Optimization (PSO)",
            "Probability Data Association (PDA)",
            "Systematic biases"
        ],
        "venue": "Chinese Control Conference, CCC",
        "year": 2013,
        "id": "h0wpFOQT"
    },
    "mw40q6fJ": {
        "authors": [
            {
                "name": "Qingchen Zhou",
                "org": "Electronic Information Department"
            },
            {
                "name": "Huotao Gao",
                "org": "Electronic Information Department"
            },
            {
                "name": "Huajun Zhang",
                "org": "Electronic Information Department"
            },
            {
                "name": "Lin Zhou",
                "org": "Electronic Information Department"
            },
            {
                "name": "Fan Wang",
                "org": "Electronic Information Department"
            }
        ],
        "title": "Pattern synthesis method applied in designing HF superdirective receive arrays",
        "abstract": "Low side lobe level (SLL) and forming nulls can help to realize high-frequency (HF) superdirective receive arrays. In this letter, we reformulate the problem of designing an HF superdirective receive array as a problem of pattern synthesis. Based on the adaptive array theory, we present a numerical pattern synthesis algorithm combined with the design of HF superdirective receive array. Compared with the existing methods for superdirective array design, new method has more advantages in suppressing interferences and clutter. To confirm the effectiveness of novel method, numerical simulations are conducted. \u00a9 IEICE 2013.",
        "keywords": [
            "Hf receive array",
            "Pattern synthesis",
            "Superdirective"
        ],
        "venue": "IEICE Electronics Express",
        "year": 2013,
        "id": "mw40q6fJ"
    },
    "8mijCXEF": {
        "authors": [
            {
                "name": "Huotao Gao",
                "org": "School of Electronic Information"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Electronic Information"
            },
            {
                "name": "Huaqiao Zhao",
                "org": "School of Electronic Information"
            },
            {
                "name": "Huajun Zhang",
                "org": "School of Electronic Information"
            },
            {
                "name": "Jie Shi",
                "org": "School of Electronic Information"
            },
            {
                "name": "Xiaolin Zhang",
                "org": "School of Electronic Information"
            }
        ],
        "title": "Antenna of high frequency ground wave ocean-state monitoring radar",
        "abstract": "The development of high frequency ground wave radar (HFGWR) antenna at home and abroad in the past 40 years is detailed introduced and summarized, and some practical key issues in anktennoc design are systematically analyzed, and the development trend of antennas is also predicted. At last, based on the requirements of a certain HFGWR system, a new antenna design scheme is proposed and investigated. Copyright \u00a9 2013 by Editorial Department of Chinese Journal of Radio Science.",
        "keywords": [
            "Antenna technology",
            "High frequency ground wave radar (HFGWR)"
        ],
        "venue": "Dianbo Kexue Xuebao/Chinese Journal of Radio Science",
        "year": 2013,
        "id": "8mijCXEF"
    },
    "nwvgXOMZ": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Quantum-Functional Semiconductor Research Center"
            },
            {
                "name": "Yan-Xia Shang",
                "org": "Quantum-Functional Semiconductor Research Center"
            },
            {
                "name": "Ze-Song Wang",
                "org": "School of Physics and Technology"
            },
            {
                "name": "Rui Zhang",
                "org": "School of Physics and Technology"
            },
            {
                "name": "Zao-Di Zhang",
                "org": "School of Physics and Technology"
            },
            {
                "name": "Vasiliy O. Pelenovich",
                "org": "School of Physics and Technology"
            },
            {
                "name": "De-Jun Fu",
                "org": "School of Physics and Technology"
            },
            {
                "name": "Kang Tae Won",
                "org": "Quantum-Functional Semiconductor Research Center"
            }
        ],
        "title": "Optical and magnetic properties of InFeP layers prepared by Fe+ implantation",
        "abstract": "InFeP layers are prepared by ion implantation of InP with 100-keV Fe ",
        "keywords": [
            "diluted magnetic semiconductor",
            "ion implantation",
            "photoluminescence",
            "Rutherford backscattering/channeling"
        ],
        "venue": "Chinese Physics B",
        "year": 2013,
        "id": "nwvgXOMZ"
    },
    "PtKi8LlS": {
        "authors": [
            {
                "name": "Chang Sheng Wan",
                "org": "Southeast University"
            },
            {
                "name": "Juan Zhang",
                "org": "Nanjing University"
            },
            {
                "name": "Lin Zhou",
                "org": "Southeast University"
            },
            {
                "name": "Zhong Yuan Qin",
                "org": "Southeast University"
            }
        ],
        "title": "Using the pairing function for distributed access control in cloud computig",
        "keywords": [
            "Access control",
            "Authorization",
            "Cloud computing",
            "RBAC"
        ],
        "venue": "Advanced Materials Research",
        "year": 2013,
        "id": "PtKi8LlS"
    },
    "ssLbETDE": {
        "authors": [
            {
                "name": "Xiaoyan Zhao",
                "org": "Key Laboratory of Underwater Acoustic Signal Processing of Ministry of Education"
            },
            {
                "name": "Jie Tang",
                "org": "School of Information Science and Engineering"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Underwater Acoustic Signal Processing of Ministry of Education"
            },
            {
                "name": "Zhenyang Wu",
                "org": ""
            }
        ],
        "title": "A fast search method of steered response power with small-aperture microphone array for sound source localization",
        "abstract": "The Steered Response Power (SRP) method works well for sound source localization in noisy and reverberant environment. However, the large computation complexity limits its practical application. In this paper, a fast SRP search method is proposed to reduce the computational complexity using small-aperture microphone array. The proposed method inspired by the SRP spatial spectrum includes two steps: first, the proposed method estimates the azimuth of the sound source roughly and determines whether the sound source is in far field or near field; then, different fine searching operations are performed according to the sound source being in far field or near field. Experiments both in simulation environments and real environments have been performed to compare the localization accuracy and computation complexity of the proposed method with those of the conventional SRP-PHAT algorithm. The results show that, the proposed method has a comparative accuracy with the conventional SRP algorithm, and achieves a reduction of 93.62% in computation complexity compared to the conventional SRP algorithm. \u00a9 2013 Science Press, Institute of Electronics, CAS and Springer-Verlag Berlin Heidelberg.",
        "keywords": [
            "Small-aperture microphone array",
            "Sound source localization",
            "Steered Response Power (SRP)",
            "Three-line method"
        ],
        "venue": "Journal of Electronics",
        "year": 2013,
        "id": "ssLbETDE"
    },
    "LSOuiVie": {
        "authors": [
            {
                "name": "Xiaoxue Feng",
                "org": "School of Automation"
            },
            {
                "name": "Yan Liang",
                "org": "School of Automation"
            },
            {
                "name": "Lianmeng Jiao",
                "org": "School of Automation"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Automation"
            }
        ],
        "title": "Mode identification and positioning accuracy improvement using forward-based receivers for OTHR",
        "abstract": "Target tracking of over-the-horizon radar (OTHR) faces the challenge of low detection probability, low sampling rate, low measurement accuracy and multipath propagation. Both mode recognition of multipath propagation and target localization, significantly affect data association and estimate updating. In this paper, a scheme of measurement fusion of OTHR and forward-based receivers (FBRs) is presented to identify propagation modes and improve positioning accuracy. A coordinate transformation formula related to the target height is derived, and the measurements of FBRs are fused to obtain the preliminary estimates of the target state and ionosphere heights via an iterative least square method. Based on the above position estimate and OTHR measurements, a maximum-likelihood-estimation-based rule is proposed to identify the propagation/clutter modes. Finally, a minimum variance estimation method is given to improve positioning accuracy by fusing the associated data from OTHR and FBRs in ground coordinates. Simulation results show that the identification of propagation modes is satisfactory, the ionospheric heights and target heights can be estimated, and there is significant positioning accuracy improvement through fusing measurements of OTHR and FBRs.",
        "keywords": [
            "Data fusion",
            "Forward-based receiver",
            "Mode identification",
            "Over-the-horizon radar (OTHR)",
            "Positioning accuracy",
            "Target tracking"
        ],
        "venue": "Hangkong Xuebao/Acta Aeronautica et Astronautica Sinica",
        "year": 2013,
        "id": "LSOuiVie"
    },
    "sBau9okG": {
        "authors": [
            {
                "name": "Nan Ma",
                "org": "College of Information Technology"
            },
            {
                "name": "Yun Zhai",
                "org": "E-Govemment Research Center"
            },
            {
                "name": "Wen-Fa Li",
                "org": "College of Information Technology"
            },
            {
                "name": "Cui-Hua Li",
                "org": "Department of GSH Information-Based"
            },
            {
                "name": "Shan-Shan Wang",
                "org": "College of Information Technology"
            },
            {
                "name": "Lin Zhou",
                "org": "College of Information Technology"
            }
        ],
        "title": "Neural network algorithm based method for stock price trend prediction",
        "abstract": "Neural network algorithm is very suitable for stock prediction as a model for dealing with complicated relationship. However, the prediction accuracy of neural network algorithm depends largely on the number of hidden nodes and the terminal condition. To follow up the changes in stock prices, a new method is proposed in this study to find out the optimal parameter. The recommended solution is setting fewer hidden nodes and lower holdout percentage. Results show that the proposed method can lessen about 60% of the forecast error such that it can ensure the efficiency and accuracy of the algorithm. \u00a9 2013 Asian Network for Scientific Information.",
        "keywords": [
            "Data mining",
            "Hidden nodes",
            "Neural network algorithm",
            "Stock prediction"
        ],
        "venue": "Journal of Applied Sciences",
        "year": 2013,
        "id": "sBau9okG"
    },
    "dPSZ2oH1": {
        "authors": [
            {
                "name": "Zhen-Hua Wan",
                "org": "Department of Modern Mechanics"
            },
            {
                "name": "Lin Zhou",
                "org": "Institute of Structural Mechanics"
            },
            {
                "name": "Hai-Hua Yang",
                "org": "Department of Modern Mechanics"
            },
            {
                "name": "De-Jun Sun",
                "org": "Department of Modern Mechanics"
            }
        ],
        "title": "Large eddy simulation of flow development and noise generation of free and swirling jets",
        "abstract": "Large eddy simulation is performed for investigating the local and far-field behaviors of free and swirling jets at moderate Reynolds number. By solving compressible boundary layer equations, the inflow profiles with different swirl number are calculatedthen their stability characteristics are analyzed based on linear stability theory. The amplification rates of swirling jets are higher than the free one, particularly for higher or negative azimuthal wavenumber modes. Multiple unstable modes are superimposed to construct inflow forcing. The quantities of flow and acoustic are presented and compared against the results of existed experiments and other computations, besides, the comparisons are also made among themselves. For swirling jets, the spreadings of jet half-width and vorticity thickness at the initial and transition stage are enhanced, but they are surpassed by the free jet at turbulent mixing stage. In all cases, the development of mixing layer initially is greatly influenced by frequencies f0 and f0/2 associated with upstream forcing. As the swirl intensity is increased, the growth rates of fluctuation quantities on the centerline and the nozzle lip line are raised, but the peak levels on the centerline are reduced substantially. In swirling jets, the strength of vortex pairing is decreasedthe pairing noise is weakened correspondingly. The overall sound pressure levels are lower than that of the free jet at all observation angles (\u03c6{symbol})about 3 decibels (dB) is reduced at \u03c6{symbol} \u2243 30\u00b0 in the strong swirling case at a distance of 60 radii. The Fourier analyses of pressure and acoustic sources show that the modes are varied greatly, which suggests that the noise reduction should be corresponding to the change of instability waves. \u00a9 2013 AIP Publishing LLC.",
        "keywords": [
            ""
        ],
        "venue": "Physics of Fluids",
        "year": 2013,
        "id": "dPSZ2oH1"
    },
    "vgrFWW5r": {
        "authors": [
            {
                "name": "Jian-Min Qi",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Shi-Lun Jiang",
                "org": ""
            },
            {
                "name": "Jian-Hua Zhang",
                "org": ""
            }
        ],
        "title": "Experimental studies on pulsed neutron sensitivity of a fusion neutron spectrometer",
        "abstract": "A sensitivity optimized magnetic proton recoil (MPROS) spectrometer for measuring both steady and pulsed fusion neutron spectra in several complicated environments is developed. The proton energy-position projection relationship of the spectrometer is measured by utilizing an imaging plate. The energy response to neutron sensitivity of the MPROS spectrometer is studied through a single event count method on an accelerated steady DT neutron source and simulations by a three-dimensional charged particle transport code. The detection efficiency of the spectrometer to DT neutrons reaches a level of 2\u00d710",
        "keywords": [
            "Fusion neutron spectrum",
            "Magnetic proton recoil",
            "Particle transport",
            "Pulsed neutron sensitivity"
        ],
        "venue": "Wuli Xuebao/Acta Physica Sinica",
        "year": 2013,
        "id": "vgrFWW5r"
    },
    "ZPd9aYBm": {
        "authors": [
            {
                "name": "Xiaowei Zhang",
                "org": "School of Information Science and Engineering"
            },
            {
                "name": "Bin Hu",
                "org": "School of Information Science and Engineering"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Information Science and Engineering"
            },
            {
                "name": "Jing Chen",
                "org": "School of Information Science and Engineering"
            },
            {
                "name": "Philip Moore",
                "org": "School of Computing, Telecommunications and Networks"
            }
        ],
        "title": "An XML format for electroencephalogram data presentation (eegML)",
        "abstract": "With the development of the electronic health record, sharing biomedical and healthcare data among heterogeneous systems has great potential to benefit both clinical healthcare and scientific research. Standardizing the data presentation is the best solution to exchange them among heterogeneous systems. However, electroencephalogram (EEG) data has met problems since existing diverse data formats are unsuitable for this purpose. To address this problem we introduce an XML-based data presentation method named eegML for EEG in this paper. Based on advantages of XML technologies, eegML is a generic system- and application-independent and flexible open solution to the effective presentation of EEG data. Besides, eegML could also be used to aid knowledge management and discovery in biomedical and healthcare informatics. This format, if widely adopted, could better promote EEG data management and mining. \u00a9 2013 IEEE.",
        "keywords": [
            "Data presentation",
            "EEG data",
            "Healthcare data management",
            "XML"
        ],
        "venue": "Proceedings - 2013 IEEE International Conference on Bioinformatics and Biomedicine, IEEE BIBM 2013",
        "year": 2013,
        "id": "ZPd9aYBm"
    },
    "E6RllMKJ": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of MEMS"
            },
            {
                "name": "Sheng-Qi Cheng",
                "org": "Key Laboratory of MEMS"
            },
            {
                "name": "Tian-Yu Xiang",
                "org": "Key Laboratory of MEMS"
            },
            {
                "name": "Ming Qin",
                "org": "Key Laboratory of MEMS"
            },
            {
                "name": "Bei Cheng",
                "org": "Key Laboratory of MEMS"
            },
            {
                "name": "Qing-An Huang",
                "org": "Key Laboratory of MEMS"
            }
        ],
        "title": "Wide span thermal wind sensor system with dual chips",
        "abstract": "A novel thermal wind sensor system based on dual chips was presented in this paper. One chip is thermal anemometer, which operates in Constant Temperature Difference (CTD) mode, another is calorimetric wind sensor, which operates in Constant Power (CP) mode. Both chips are designed to work at the same time. In the low wind speed (from 0 to 10m/s for example), the CP mode chip can detect accurate wind velocity and direction with less temperature drift, which is used as a reference for calculating the offset voltage of the CTD mode chip caused by the variation of ambient temperature; meanwhile the data are also as the output of the system. So compared with single chip wind sensors, the dual chips wind system can detect both low and high wind speed with higher accuracy and less temperature drift. The testing results indicate that the accuracy of low wind speed under 10m/s is \u00b10.3m/s and that of high speed from 10m/s to 40m/s is \u00b10.6m/s, and the measurement span is above 40m/s. In this system, dual chips are designed to operate in two different modes and their outputs are detected by a Micro Controller Unit (MCU). \u00a9 2013 IEEE.",
        "keywords": [
            ""
        ],
        "venue": "IEEE SENSORS 2013 - Proceedings",
        "year": 2013,
        "id": "E6RllMKJ"
    },
    "TmOHLdH5": {
        "authors": [
            {
                "name": "Wenlin Liao",
                "org": "College of Mechatronics and Automation"
            },
            {
                "name": "Yifan Dai",
                "org": "College of Mechatronics and Automation"
            },
            {
                "name": "Xuhui Xie",
                "org": "College of Mechatronics and Automation"
            },
            {
                "name": "Lin Zhou",
                "org": "College of Mechatronics and Automation"
            }
        ],
        "title": "Microscopic morphology evolution during ion beam smoothing of Zerodur\u00ae surfaces",
        "abstract": "Ion sputtering of Zerodur material often results in the formation of nanoscale microstructures on the surfaces, which seriously influences optical surface quality. In this paper, we describe the microscopic morphology evolution during ion sputtering of Zerodur surfaces through experimental researches and theoretical analysis, which shows that preferential sputtering together with curvature-dependent sputtering overcomes ion-induced smoothing mechanisms leading to granular nanopatterns formation in morphology and the coarsening of the surface. Consequently, we propose a new method for ion beam smoothing (IBS) of Zerodur optics assisted by deterministic ion beam material adding (IBA) technology. With this method, Zerodur optics with surface roughness down to 0.15nm root mean square (RMS) level is obtained through the experimental investigation, which demonstrates the feasibility of our proposed method. \u00a9 2014 Optical Society of America.",
        "keywords": [
            ""
        ],
        "venue": "Optics Express",
        "year": 2014,
        "id": "TmOHLdH5"
    },
    "34iO6VQm": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "College of Engineering"
            },
            {
                "name": "Lan Jun Liu",
                "org": "College of Engineering"
            },
            {
                "name": "Shu Kai Chi",
                "org": "College of Engineering"
            }
        ],
        "title": "Reliability analysis of turbo code for high-speed underwater acoustic communicationbased on OFDM",
        "abstract": "With the rapid development of OFDM (Orthogonal Frequency Division Multiplexing) technology and its own advantages, this technology has been studied actively in underwater acoustic communication recently to improve the data transfer rate and reliability. This paper introduces the key technology of high speed OFDM underwater acoustic communication, analyzes the advantages and disadvantages, design a high-speed underwater acoustic OFDM communication coding scheme based on TURBO code, and proceeding the simulation and analysis for the OFDM system. Finally, the reliability of TURBO code in high speed underwater acoustic OFDM communication is analyzed. \u00a9 (2014) Trans Tech Publications, Switzerland.",
        "keywords": [
            "OFDM",
            "Reliability analysis",
            "Turbo code",
            "Underwater acoustic communication"
        ],
        "venue": "Applied Mechanics and Materials",
        "year": 2014,
        "id": "34iO6VQm"
    },
    "hW3WIHoq": {
        "authors": [
            {
                "name": "Jin Feng Zhao",
                "org": "MESNAC Co., Ltd"
            },
            {
                "name": "Ming Li",
                "org": "Ocean University of China"
            },
            {
                "name": "Lin Zhou",
                "org": "Ocean University of China"
            }
        ],
        "title": "Design on the polymertemperature control system for tandem mixer",
        "abstract": "Polymer mixing is the key process of rubber products manufacturing, and mixer is the core equipment in polymer mixing process. By analysis of the effective factors on mixer mixing temperature, this paper study realization method of temperature control system. A polymer temperature control system using tandem mixing technology is designed to improve the mixing efficiency and the quality. \u00a9 (2014) Trans Tech Publications, Switzerland.",
        "keywords": [
            "Mixer",
            "Saving energy and reducing consumption",
            "Tandem mixing",
            "Temperature control system"
        ],
        "venue": "Applied Mechanics and Materials",
        "year": 2014,
        "id": "hW3WIHoq"
    },
    "WSqTPAHd": {
        "authors": [
            {
                "name": "Yibin Tang",
                "org": "College of IOT Engineering, Hohai University"
            },
            {
                "name": "Ning Xu",
                "org": "College of IOT Engineering, Hohai University"
            },
            {
                "name": "Cheng Yao",
                "org": "College of IOT Engineering, Hohai University"
            },
            {
                "name": "Changping Zhu",
                "org": "College of IOT Engineering, Hohai University"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Information Science and Engineering, Southeast University"
            }
        ],
        "title": "Image denoising via rotation invariant sparse representation and manifold learning",
        "abstract": "An image denoising algorithm is proposed via rotation invariant sparse representation and manifold learning. The algorithm firstly builds the sparse model based on manifold learning for the image patches, and makes the spare coefficients maintain consistent manifold structure with corresponding image patches. Meanwhile, due to the strong rotation invariant relation among the image patches, the algorithm adopts block rotation to further enhance the performance of sparse reconstruction under the manifold constraint. In details, an optimal approach is proposed to solve the sparse model. With a series of model transforms, the sparse model satisfies the classic framework of K-SVD algorithm, and the iterative optimal solution is achieved under this framework. Experiment results demonstrate that the proposed sparse model can effectively establish the structural relation among the image patches, especially the rotated image patches, extract the hidden features in the noisy image patches, improve the PSNR of the reconstructed image and obtain better denoising performance compared with traditional sparse denoising algorithms.",
        "keywords": [
            "Image denoising",
            "Manifold learning",
            "Rotation invariant",
            "Sparse representation"
        ],
        "venue": "Yi Qi Yi Biao Xue Bao/Chinese Journal of Scientific Instrument",
        "year": 2014,
        "id": "WSqTPAHd"
    },
    "BD3cQzSC": {
        "authors": [
            {
                "name": "Suofei Zhang",
                "org": "School of Internet of Things, Nanjing University of Posts and Telecommunications"
            },
            {
                "name": "Xu Cheng",
                "org": "School of Information Science and Engineering, Southeast University"
            },
            {
                "name": "Haiyan Guo",
                "org": "School of Information Science and Engineering, Southeast University"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Information Science and Engineering, Southeast University"
            },
            {
                "name": "Zhenyang Wu",
                "org": "School of Information Science and Engineering, Southeast University"
            }
        ],
        "title": "Tracking deformable parts via dynamic conditional random fields",
        "abstract": "Despite the success of many advanced tracking methods in this area, tracking targets with drastic variation of appearance such as deformation, view change and partial occlusion in video sequences is still a challenge in practical applications. In this paper, we take these serious tracking problems into account simultaneously, proposing a dynamic graph based model to track object and its deformable parts at multiple resolutions. The method introduces well learned structural object detection models into object tracking applications as prior knowledge to deal with deformation and view change. Meanwhile, it explicitly formulates partial occlusion by integrating spatial potentials and temporal potentials with an unparameterized occlusion handling mechanism in the dynamic conditional random field framework. Empirical results demonstrate that the method outperforms state-of-the-art trackers on different challenging video sequences.",
        "keywords": [
            "computer vision",
            "conditional random field",
            "deformable part based model",
            "object tracking"
        ],
        "venue": "2014 IEEE International Conference on Image Processing, ICIP 2014",
        "year": 2015,
        "id": "BD3cQzSC"
    },
    "0I4RCzA7": {
        "authors": [
            {
                "name": "Sheng Qi Chen",
                "org": "Key Laboratory for MEMS of Education Ministry of China, Southeast University"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory for MEMS of Education Ministry of China, Southeast University"
            },
            {
                "name": "Ming Qin",
                "org": "Key Laboratory for MEMS of Education Ministry of China, Southeast University"
            }
        ],
        "title": "Silicon thermal flow sensor based on ceramic substrate",
        "abstract": "A silicon thermal flow-sensor system based on ceramic substrate is described in this paper. The sensor chip is mounted on a ceramic substrate with a metal heat sink. The simulation by ANSYS software and the experiment are done for determining suitable package size. The results from the ANSYS simulation and the standard flow test in the flow tunnel show that when the radius of the ceramic is 10mm and the heat conduction is 35Wm ",
        "keywords": [
            "ANSYS",
            "Flow-sensor",
            "MEMS packaging"
        ],
        "venue": "Key Engineering Materials",
        "year": 2014,
        "id": "0I4RCzA7"
    },
    "A8wJUie6": {
        "authors": [
            {
                "name": "Chuan Liang",
                "org": ""
            },
            {
                "name": "Lulin Xi",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Zeping Xu",
                "org": ""
            },
            {
                "name": "Zhenghong Li",
                "org": ""
            },
            {
                "name": "Linwen Zhang",
                "org": ""
            }
        ],
        "title": "Investigation and application of a portable 150 kV flash X-ray system",
        "abstract": "A portable 150 kV flash X-ray system based on fast rise time mini-Marx generator principle was designed in coaxial structure. The experimental results of a 10-stage 150 kV Mini-Marx generator and flash X-ray tube were described. With a flash X-ray tube integrated directly into the Mini-Marx generator as a load, the formed flash X-ray system generated a dose of 7.7\u00d710",
        "keywords": [
            "Computed radiography",
            "Flash photography",
            "Mini-Marx generator",
            "Portable flash X-ray system"
        ],
        "venue": "Qiangjiguang Yu Lizishu/High Power Laser and Particle Beams",
        "year": 2014,
        "id": "A8wJUie6"
    },
    "iLFTsrQG": {
        "authors": [
            {
                "name": "Qi Gao",
                "org": ""
            },
            {
                "name": "Chuanfei Zhang",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Zhenghong Li",
                "org": ""
            },
            {
                "name": "Zeqing Wu",
                "org": ""
            },
            {
                "name": "Yu Lei",
                "org": ""
            },
            {
                "name": "Chunlai Zhang",
                "org": ""
            },
            {
                "name": "Xiaotao Zu",
                "org": ""
            }
        ],
        "title": "One-dimensional nonequilibrium radiation-transport equation under diffusion approximation and its discrete scheme",
        "abstract": "Based on the nonlocal thermodynamic equilibrium state and large optical thickness of plasma, we establish one-dimensional nonequilibrium radiation-transport equation from diffusion approximation. Through finite volume method, the discrete scheme of radiation-transport equation and the conditions for its definite solution are proposed. The reliability of radiation-transport equation and its discrete scheme is validated. \u00a9 2014 Qi Gao et al.",
        "keywords": [
            ""
        ],
        "venue": "Advances in Condensed Matter Physics",
        "year": 2014,
        "id": "iLFTsrQG"
    },
    "ofA68Mdu": {
        "authors": [
            {
                "name": "Wenlin Liao",
                "org": "Hunan Key Laboratory of Ultra-Precision Machining Technology"
            },
            {
                "name": "Yifan Dai",
                "org": "Hunan Key Laboratory of Ultra-Precision Machining Technology"
            },
            {
                "name": "Xuhui Xie",
                "org": "College of Mechatronics and Automation, National University of Defense Technology"
            },
            {
                "name": "Lin Zhou",
                "org": "College of Mechatronics and Automation, National University of Defense Technology"
            }
        ],
        "title": "Influence of local densification on microscopic morphology evolution during ion-beam sputtering of fused-silica surfaces",
        "abstract": "Morphology evolution at microscopic scales has an inseparable relationship with surface material behaviors, especially during ultrasmooth surface fabrication. In this work, the influence of initially existing local densification on ion nanopatterning of a fused-silica surface is investigated. Our research results indicate that fused-silica surfaces will easily densify permanently under a compressive load, exhibiting an anisotropic surface at the nanoscale. During the subsequent ion-beam sputtering process, the densification-dependent sputtering would influence and even dominate surface morphology evolution, which is identified as being an important evolution mechanism. However, ion-induced relaxation mechanisms will overcome surface roughening in the absence of local densification, and an ultrasmooth surface with root mean square roughness down to 0.06 nm is obtained in our experiment.",
        "keywords": [
            ""
        ],
        "venue": "Applied Optics",
        "year": 2014,
        "id": "ofA68Mdu"
    },
    "sqYrP5hy": {
        "authors": [
            {
                "name": "Xu Cheng",
                "org": "School of Information Science and Engineering, Southeast University"
            },
            {
                "name": "Nijun Li",
                "org": "School of Information Science and Engineering, Southeast University"
            },
            {
                "name": "Tongchi Zhou",
                "org": "School of Information Science and Engineering, Southeast University"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Information Science and Engineering, Southeast University"
            },
            {
                "name": "Zhenyang Wu",
                "org": "School of Information Science and Engineering, Southeast University"
            }
        ],
        "title": "Visual tracking via sparse representation and online dictionary learning",
        "abstract": "Sparse representation has been shown competitive performance on single object tracking. In this paper, we extend this technique to tracking multiple interactive objects and present a novel sparse tracker under the tracking- by-detection framework, with saliency detector for objects detection and sparse representation for objects association. Furthermore, we propose an online dictionary learning scheme to capture appearance variations of objects. To avoid using trivial templates, the dictionary contains not only objects templates, but also background information, resulting in more robust estimation. The experiments demonstrate that our approach achieves favorable performance over stateof-the-art algorithms.",
        "keywords": [
            "Appearance model",
            "L1 minimization",
            "Multiple objects tracking",
            "Online dictionary learning",
            "Sparse representation"
        ],
        "venue": "Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)",
        "year": 2014,
        "id": "sqYrP5hy"
    },
    "D99pTgak": {
        "authors": [
            {
                "name": "X. Cheng",
                "org": "School of Information Science and Engineering, Southeast University"
            },
            {
                "name": "Nijun Li",
                "org": "School of Information Science and Engineering, Southeast University"
            },
            {
                "name": "Tongchi Zhou",
                "org": "School of Information Science and Engineering, Southeast University"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Information Science and Engineering, Southeast University"
            },
            {
                "name": "Zhenyang Wu",
                "org": "School of Information Science and Engineering, Southeast University"
            }
        ],
        "title": "Visual Tracking via Sparse Representation and Online Dictionary Learning",
        "abstract": "Sparse representation has been shown competitive performance on single object tracking. In this paper, we extend this technique to tracking multiple interactive objects and present a novel sparse tracker under the tracking- by-detection framework, with saliency detector for objects detection and sparse representation for objects association. Furthermore, we propose an online dictionary learning scheme to capture appearance variations of objects. To avoid using trivial templates, the dictionary contains not only objects templates, but also background information, resulting in more robust estimation. The experiments demonstrate that our approach achieves favorable performance over stateof- the-art algorithms.",
        "keywords": [
            "Appearance model",
            "L1 minimization",
            "Multiple objects tracking",
            "Online dictionary learning",
            "Sparse representation"
        ],
        "venue": "Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)",
        "year": 2014,
        "id": "D99pTgak"
    },
    "4FFgV1ni": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Lan Lan Kang",
                "org": ""
            },
            {
                "name": "Shu Kai Chi",
                "org": ""
            }
        ],
        "title": "The cell search procedure and PCI planning in TD-LTE",
        "abstract": "The first step is cell search procedure for a user terminal in TD-LTE. It\u2019s the premise of the establishment of a communication link between the user terminal and the base station. To detect PCI correctly plays a crucial role in the cell search procedure, and it also affects the mobility of the user terminal. It\u2019s a problem that is worth studying how to determine the PCI planning in TD-LTE. This article first briefly introduces the PCI parameter and the cell research procedure, and specifies the PCI is the important parameter for LTE, and then describes the planning principles of the parameter. Finally, it specifies the suggestions and situations of the PCI planning in test network of TD-LTE.",
        "keywords": [
            "Cell reference signal",
            "Physical cell identity",
            "Primary synchronization sequence(PSS)",
            "Second synchronization sequence(SSS)"
        ],
        "venue": "Applied Mechanics and Materials",
        "year": 2014,
        "id": "4FFgV1ni"
    },
    "UUVMJssA": {
        "authors": [
            {
                "name": "Huajun Zhang",
                "org": "Electronic Information Department"
            },
            {
                "name": "Huotao Gao",
                "org": "Electronic Information Department"
            },
            {
                "name": "Qingchen Zhou",
                "org": "Electronic Information Department"
            },
            {
                "name": "Lin Zhou",
                "org": "Electronic Information Department"
            },
            {
                "name": "Fan Wang",
                "org": "Electronic Information Department"
            }
        ],
        "title": "A novel digital beamformer applied in vehicle mounted HF receiving device",
        "abstract": "In this work, a novel digital beamformer applied in vehicle-mounted high frequency (HF) receiving device has been developed. The system adopts robust superdirective beamforming algorithm, which not only effectively reduces the receiving array aperture but also maintains a higher directive gain compared with conventional beamforming method (CBF). The system is designed based on the idea of radio-defined software (SDR), which is easy to update. It contains 16 receiving channels and can output 3 analog beam signals. Experiment shows that the system has fast response and is feasible in engineering. \u00a9 IEICE 2014.",
        "keywords": [
            "Digital beamformer",
            "Robust superdirective beamforming",
            "Software-defined radio",
            "Uniform circular array"
        ],
        "venue": "IEICE Electronics Express",
        "year": 2014,
        "id": "UUVMJssA"
    },
    "IMC3FMNW": {
        "authors": [
            {
                "name": "Qi Gao",
                "org": "University of Electronic Science and Technology of China"
            },
            {
                "name": "Chuan-Fei Zhang",
                "org": "Institute of Nuclear Physics and Chemistry, CAEP"
            },
            {
                "name": "Lin Zhou",
                "org": "Institute of Nuclear Physics and Chemistry, CAEP"
            },
            {
                "name": "Zheng-Hong Li",
                "org": "Institute of Nuclear Physics and Chemistry, CAEP"
            },
            {
                "name": "Ze-Qing Wu",
                "org": "Institute of Applied Physics and Computational Mathematics"
            },
            {
                "name": "Yu Lei",
                "org": "University of Electronic Science and Technology of China"
            },
            {
                "name": "Chun-Lai Zhang",
                "org": "University of Electronic Science and Technology of China"
            },
            {
                "name": "Xiao-Tao Zu",
                "org": "University of Electronic Science and Technology of China"
            }
        ],
        "title": "Separating the Z-pinch plasma X-ray radiation and attaining the electron temperature",
        "abstract": "According to the experimental results of spectrum diagnosis made on Qiang-Guang-I generator, we report a method to separate and diagnose Z-pinch plasma radiation spectrum. Spectral lines and different continuums are separated from experimental results and electron temperatures can be acquired. Results show that continuums are superposed by radiation of high electron temperature plasma at the centre field (T",
        "keywords": [
            "Electron temperature",
            "Spectrum diagnose",
            "Spectrum separation",
            "Z-pinch"
        ],
        "venue": "Wuli Xuebao/Acta Physica Sinica",
        "year": 2014,
        "id": "IMC3FMNW"
    },
    "FSipMqIc": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Underwater Acoustic Signal Processing of Ministry of Education, Southeast University"
            },
            {
                "name": "Xiaoyan Zhao",
                "org": "Key Laboratory of Underwater Acoustic Signal Processing of Ministry of Education, Southeast University"
            },
            {
                "name": "Xu Cheng",
                "org": "Key Laboratory of Underwater Acoustic Signal Processing of Ministry of Education, Southeast University"
            },
            {
                "name": "Nijun Li",
                "org": "Key Laboratory of Underwater Acoustic Signal Processing of Ministry of Education, Southeast University"
            },
            {
                "name": "Zhenyang Wu",
                "org": "Key Laboratory of Underwater Acoustic Signal Processing of Ministry of Education, Southeast University"
            }
        ],
        "title": "Robust binaural sound source localization based on sub-band SNR estimation and soft decision",
        "abstract": "In order to improve the localization performance in noisy and reverberation environments, a robust binaural sound source localization (SSL) algorithm based on sub-band signal-to-noise ratio (SNR) estimation and soft decision is proposed. First, sub-band SNR is estimated based on the autocorrelation matrix of sub-band binaural sound signals in each frame. Then, the sub-band SNR is mapped to soft decision value, and the cross power spectrum density (PSD) of binaural sound signal is weighted by soft decision. Finally, inter-aural time difference (ITD) is computed by weighted cross PSD, and the azimuth of sound source is estimated. Simulation and real environment test results show that, compared with the conventional binaural SSL algorithms based on cross correlation and zeros crossing, the localization performance of the proposed algorithm is significantly improved in complex acoustic environments.",
        "keywords": [
            "Binaural sound source localization",
            "Inter-aural time difference",
            "Soft decision",
            "Sub-band signal-to-noise ratio estimation"
        ],
        "venue": "Dongnan Daxue Xuebao (Ziran Kexue Ban)/Journal of Southeast University (Natural Science Edition)",
        "year": 2015,
        "id": "FSipMqIc"
    },
    "NQINhVfq": {
        "authors": [
            {
                "name": "Xu Cheng",
                "org": "School of Information Science and Engineering, Southeast University"
            },
            {
                "name": "Nijun Li",
                "org": "School of Information Science and Engineering, Southeast University"
            },
            {
                "name": "Tongchi Zhou",
                "org": "School of Information Science and Engineering, Southeast University"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Information Science and Engineering, Southeast University"
            },
            {
                "name": "Zhenyang Wu",
                "org": "School of Information Science and Engineering, Southeast University"
            }
        ],
        "title": "Object tracking via collaborative multi-task learning and appearance model updating",
        "abstract": "In this paper, we propose a novel visual tracking algorithm using the collaboration of generative and discriminative trackers under the particle filter framework. Each particle denotes a single task, and we encode all the tasks simultaneously in a structured multi-task learning manner. Then, we implement generative and discriminative trackers, respectively. The discriminative tracker considers the overall information of object to represent the object appearance; while the generative tracker takes the local information of object into account for handling partial occlusions. Therefore, two models are complementary during the tracking. Furthermore, we design an effective dictionary updating mechanism. The dictionary is composed of fixed and variational parts. The variational parts are progressively updated using Metropolis-Hastings strategy. Experiments on different challenging video sequences demonstrate that the proposed tracker performs favorably against several state-of-the-art trackers.",
        "keywords": [
            "Appearance modeling",
            "Multi-task learning",
            "Particle filter",
            "Sparse representation",
            "Visual tracking"
        ],
        "venue": "Applied Soft Computing Journal",
        "year": 2015,
        "id": "NQINhVfq"
    },
    "owrKcipf": {
        "authors": [
            {
                "name": "Yong L\u00fc",
                "org": "College of Computer and Information Engineering, Hohai University"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Information Science and Engineering, Southeast University"
            }
        ],
        "title": "Model Adaptation Algorithm Based on Central Subband Regression for Robust Speech Recognition",
        "abstract": "This paper proposes a model adaptation algorithm based on central sub band regression for robust speech recognition, which uses a linear transformation to approximate the relationship between the training and testing conditions for each channel of the Mel filter bank and its adjacent channels. The maximum likelihood estimation of each channel transform is obtained by several different divisions of all the Mel channels and sub-band adaptation. The experimental results show that the proposed algorithm can obtain more accurate testing acoustic models for rapid model adaptation and outperforms the traditional sub-band regression method.",
        "keywords": [
            "central subband regression",
            "hidden Markov model",
            "model adaptation",
            "speech recognition"
        ],
        "venue": "Proceedings - 2014 7th International Symposium on Computational Intelligence and Design, ISCID 2014",
        "year": 2015,
        "id": "owrKcipf"
    },
    "7J9teSI3": {
        "authors": [
            {
                "name": "Nijun Li",
                "org": "School of Information Science and Engineering, Southeast University"
            },
            {
                "name": "Tongchi Zhou",
                "org": "School of Information Science and Engineering, Southeast University"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Information Science and Engineering, Southeast University"
            },
            {
                "name": "Zhenyang Wu",
                "org": "School of Information Science and Engineering, Southeast University"
            }
        ],
        "title": "Action recognition by Huffman coding and implicit action model",
        "abstract": "Human action recognition is at the core of computer vision, and has great application value in intelligent human-computer interactions. On the basis of Bag-of-Words (BoW), this work presents a Huffman coding and Implicit Action Model (IAM) combined framework for action recognition. Specifically, Huffman coding, which outperforms na\u00efve Bayesian method, is a robust estimation of visual words' conditional probabilities; whereas IAM captures the spatio-temporal relationships of local features and outperforms most other common machine learning methods. Spatio-Temporal Interest Points (STIPs) and Harris corners are employed as local features, and multichannel feature description is adopted to exploit the complementarity among different features. Experiments on UCF-YouTube and HOHA2 datasets systematically compare the performance of various feature channels and machine learning methods, demonstrating the effectiveness of the approaches proposed by this paper. Finally, multiple augment mechanisms such as feature fusion, hierarchical codebooks and sparse coding are integrated into the recognition system, achieving the best ever performance comparing with the state-of-the-art.",
        "keywords": [
            "action recognition",
            "feature fusion",
            "hierarchical codebooks",
            "Huffman coding",
            "implicit action model (IAM)",
            "sparse coding"
        ],
        "venue": "2015 IEEE International Conference on Computational Intelligence and Virtual Environments for Measurement Systems and Applications, CIVEMSA 2015",
        "year": 2015,
        "id": "7J9teSI3"
    },
    "ZhoQKWhL": {
        "authors": [
            {
                "name": "Haiyan Guo",
                "org": "College of Internet of Things, Nanjing University of Posts and Telecommunications"
            },
            {
                "name": "Xiaoxiong Li",
                "org": "School of Information Science and Engineering, Southeast University"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Information Science and Engineering, Southeast University"
            },
            {
                "name": "Zhenyang Wu",
                "org": "School of Information Science and Engineering, Southeast University"
            }
        ],
        "title": "Single-channel Speech Separation Using Dictionary-updated Orthogonal Matching Pursuit and Temporal Structure Information",
        "abstract": "In this paper, we propose a two-stage sparse decomposition-based method for single-channel speech separation in time domain. First, we propose a Dictionary-updated orthogonal matching pursuit (DUOMP) algorithm which is used in both separation stages. In the proposed DUOMP algorithm, all atoms of each source-specific dictionary are updated by subtracting off the current approximation of each source to the original atoms. It is proved that the DUOMP algorithm can limit the separated sources within a region where they are uncorrelated in statistical sense more quickly. Then, we propose an adaptive dictionary generation method followed by a frame labeling method to perform a second-stage separation on the mixed frames having certain temporal structure. Experiments show that the proposed method outperforms a separation method using sparse non-negative matrix factorization (SNMF), a separation method using OMP and a source-filter-based method using pitch information in overall. Additionally, what affects the performance of the proposed method is also shown.",
        "keywords": [
            "Dictionary",
            "Orthogonal matching pursuit (OMP)",
            "Single-channel speech separation (SCSS)",
            "Sparse decomposition"
        ],
        "venue": "Circuits, Systems, and Signal Processing",
        "year": 2015,
        "id": "ZhoQKWhL"
    },
    "n6ekkCw7": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Meteorological College"
            },
            {
                "name": "Shuai Song",
                "org": "Climate/Environmental Research Ctr."
            },
            {
                "name": "Hanjie Wang",
                "org": "Climate/Environmental Research Ctr."
            }
        ],
        "title": "Two-way simulations from REGCM2 coupling with SUCROS in the Huang-Huai-Hai-Plain in East China",
        "abstract": "A two-way coupling simulation from the NCAR's regional climate model REGCM2 (called R-2 hereafter) and the SUCROS model for crop growth developed by the Wageningen Agricultural University, the Netherlands (both models, when in combination, denoted as R/S) are carried out on the interactions between crops and atmosphere in the Huang-Huai-Hai Plain in East China. Evidence suggests that the R/S simulations can depict pretty well the dynamic biology-based interactions between the factors, revealing reasonably both the day-to-day variations in leaf area index (LAI) and land surface physics therein, and particularly the improvement of the simulation, independently by use of the R-2, of summer precipitation and surface temperature in the research region. As a result, the present research is of significance to the further understanding of the interaction between the climate system and the terrestrial ecological systems.",
        "keywords": [
            "Atmosphere-vegetation interactions",
            "Huang-Hua-Hai Plain",
            "Regional climate simulation",
            "Two-way coupling"
        ],
        "venue": "Acta Meteorologica Sinica",
        "year": 2003,
        "id": "n6ekkCw7"
    },
    "lcg4ss2q": {
        "authors": [
            {
                "name": "Jian Yan",
                "org": "Grad. Sch. of Chinese Acad. of Sci."
            },
            {
                "name": "Xiang-Ming Zhang",
                "org": "Kunming Institute of Botany"
            },
            {
                "name": "Zhong-Rong Li",
                "org": "Kunming Institute of Botany"
            },
            {
                "name": "Lin Zhou",
                "org": "Kunming Institute of Botany"
            },
            {
                "name": "Jian-Chao Chen",
                "org": "Grad. Sch. of Chinese Acad. of Sci."
            },
            {
                "name": "Li-Rong Sun",
                "org": "Grad. Sch. of Chinese Acad. of Sci."
            },
            {
                "name": "Ming-Hua Qiu",
                "org": "Grad. Sch. of Chinese Acad. of Sci."
            }
        ],
        "title": "Three new triterpenoids from Lycopodium japonicum THUNB",
        "abstract": "Three new triterpenoids, (3\u03b2,8\u03b2,14\u03b1,21\u03b1)-26,27- dinoronocerane-3,8,14,21-tetrol (1), (3\u03b2,8\u03b2,14\u03b1,21\u03b2)-26,27- dinoronocerane-3,8,14,21-tetrol (2), and lycopodiin A (3), together with four known compounds, lycoclavanol (4), lycoclaninol (5), \u03b1-onocerin (6), and 3-epilycoclavanol (7), were isolated from Lycopodium japonicum THUNB (Lycopodiaceae). Their structures were established by means of spectroscopic analyses. Compounds 3 and 7 showed moderate antitumor activity. Compounds 4 and 6 exhibited acetylcholinesterase inhibition activity. \u00a9 2005 Verlag Helvetica Chimica Acta AG.",
        "keywords": [
            ""
        ],
        "venue": "Helvetica Chimica Acta",
        "year": 2005,
        "id": "lcg4ss2q"
    },
    "c7Asyh8z": {
        "authors": [
            {
                "name": "Minghua Qiu",
                "org": "Key Lab. of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Shukun Chen",
                "org": "Key Lab. of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Jianchao Chen",
                "org": "Key Lab. of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Lab. of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Zhongrong Li",
                "org": "Key Lab. of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Ruilin Nie",
                "org": "Key Lab. of Phytochemistry and Plant Resources in West China"
            }
        ],
        "title": "Chemotaxonomy of cucurbitaceae",
        "abstract": "Cucurbitaceae is a bigger family and composed of 779-960 species of 110-122 genera in the world, of which 150 species of 38 genera occur in China. Many of them have been cultivated for a long time, and used as ornamental, fruit, vegetable and medicinal plants. Many genera of the family were found with cucurbitacins, but many species were not. Because of long-term cultivation and artificial reproduction, the chemical constituents of Cucurbitaceae were so complex that made the studies on and understanding of its chemical structure characters very difficult. In this paper, based on the structure characters of the chemical constituents of Cucurbitaceae, the correlation of chemical constituents with many different genera of the family was discussed, and the relation among its close genera was studied. The result indicates that the structure characters of the chemical constituents of Cucurbitaceae obtained from this paper basically support Takhtajan's classification system of this family.",
        "keywords": [
            "Chemotaxonomy",
            "Cucurbitaceae",
            "Cucurbitacins",
            "Triterpenoids"
        ],
        "venue": "Chinese Journal of Applied and Environmental Biology",
        "year": 2005,
        "id": "c7Asyh8z"
    },
    "nTGze1gA": {
        "authors": [
            {
                "name": "Zhong-Quan Zhang",
                "org": ""
            },
            {
                "name": "Jian-Chao Chen",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Ming-Hua Qiu",
                "org": ""
            }
        ],
        "title": "Two new cholestane bisdesmosides from Reineckia carnea",
        "abstract": "Three cholestane bisdesmosides, together with the corresponding aglycone, were isolated from the whole plant of Reineckia carnea. By detailed analysis of the 1D- and 2D-NMR spectra, chemical methods, and comparison with spectral data of known compounds, the structures were determined to be (1\u03b2,3\u03b2, 16\u03b2,22S)-cholest-5-ene-1,3,16,22-tetrol (1), (1\u03b2,3\u03b2,16\u03b2,22S) -cholest-5-ene-1,3,16,22-tetrol 1,16-di(\u03b2-D-glucopyranoside) (2), (1\u03b2,3\u03b2,16\u03b2,22S)-cholest-5-ene-1,3,16,22-tetrol 1-[O-\u03b1-L-rhamnopyranosyl-(1 \u2192 2)-\u03b2-D-glucopyranoside] 16-(\u03b2-D-glucopyranoside) (3), (1\u03b2,3\u03b2,16\u03b2,22S)-cholest-5-ene- 1,3,16,22-tetrol 1-(\u03b2-D-glucopyranoside) 16-(3-O-acetyl-\u03b2-D- glucopyranoside) (4). Compounds 3 and 4 appeared to be new compounds, while compound 1 was isolated for the first from a natural source. Compound 2 was isolated from the genus Reineckia for the first time. \u00a9 2007 Verlag Helvetica Chimica Acta AG.",
        "keywords": [
            ""
        ],
        "venue": "Helvetica Chimica Acta",
        "year": 2007,
        "id": "nTGze1gA"
    },
    "b0L7GdXc": {
        "authors": [
            {
                "name": "Li-Rong Sun",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Jian Yan",
                "org": "Graduate School"
            },
            {
                "name": "Lu Lu",
                "org": "Graduate School"
            },
            {
                "name": "Sheng-Ji Pei",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Zhong-Rong Li",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Xian-Min Zhang",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Ming-Hua Qiu",
                "org": "Graduate School"
            }
        ],
        "title": "Cimicifine A: A novel triterpene alkaloid from the rhizomes of Cimicifuga foetida",
        "abstract": "Cimicifine A (1), the first cycloartane triterpene alkaloid, was isolated from the rhizomes of Cimicifuga foetida, together with the known compound cimicifugoside H-1 (2). Their chemical structures were established by extensive NMR and MS analyses and by comparison with literature. \u00a9 2007 Verlag Helvetica Chimica Acta AG.",
        "keywords": [
            ""
        ],
        "venue": "Helvetica Chimica Acta",
        "year": 2007,
        "id": "b0L7GdXc"
    },
    "Mgg00PLi": {
        "authors": [
            {
                "name": "Sheng-Xiang Yang",
                "org": "National Phytochemistry Engineering Research Center in West China"
            },
            {
                "name": "Jin-Ming Gao",
                "org": "National Phytochemistry Engineering Research Center in West China"
            },
            {
                "name": "Jian-Chun Qin",
                "org": "College of Sciences"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Ming-Hua Chiu",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Lei Wang",
                "org": "College of Sciences"
            }
        ],
        "title": "Chemical constituents from Craibiodendron yunnanense",
        "abstract": "A new triterpene, (3\u03b2,12\u03b2)-taraxast-20(30)-ene-3,12-diol (=(3\u03b2,12\u03b2,18\u03b1,19\u03b1)-urs-20(30)-ene-3,12-diol; 1), together with the known compounds ursolic acid, \u03b1-amyrin, \u03b2-amyrin, (2\u03b1,3\u03b2)-2,3-dihydroxyursa-5,12-dien-28-oic acid, (2\u03b1,3\u03b2)- 2,3,23-trihydroxyurs-12-en-28-oic acid, (2S,3S,4R,8Z)-1-O-(\u03b2-D- glucopyranosyl)-2-[[(2i?)-2-hydroxydocosanoyl]amino)octadec-8-ene-l,3,4-triol, and (2S,3S,4R,8Z)-1-O-(/J-D-glucopyranosyl)-2-[(palmitoyl)amino]octadec-8-ene-l, 3,4-triol, and quercetin 3-(\u03b2-D-glucopyranoside) were isolated from the leaves of Craibiodendron yunnanense. Their structures were established on the basis of spectral evidence. The last four compounds were identified for the first time in this plant. \u00a9 2007 Verlag Helvetica Chimica Acta AG.",
        "keywords": [
            ""
        ],
        "venue": "Helvetica Chimica Acta",
        "year": 2007,
        "id": "Mgg00PLi"
    },
    "MZ5WkDIm": {
        "authors": [
            {
                "name": "Jian Yan",
                "org": "Graduate School"
            },
            {
                "name": "Ping Yi",
                "org": "Graduate School"
            },
            {
                "name": "Baohui Chen",
                "org": "Graduate School"
            },
            {
                "name": "Lu Lu",
                "org": "Graduate School"
            },
            {
                "name": "Zhongrong Li",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Xianmin Zhang",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Minghua Qiu",
                "org": "Graduate School"
            }
        ],
        "title": "Polyhydroxyserratane triterpenoids from Diphasiastrum complanatum",
        "abstract": "Serratane triterpenoids were identified from Diphasiastrum complanatum (L.) Holub, including serratane-3\u03b1,14\u03b1,15\u03b1,20\u03b2,21\u03b2,24,29-heptol (1), 3\u03b1,20\u03b2,21\u03b2-trihydroxyserrat-14-en-24-oic acid (2), 3\u03b2,20\u03b2,21\u03b2-trihydroxyserrat-14-en-24-oic acid (3), 3\u03b1,20\u03b2,21\u03b2-trihydroxy-16-oxoserrat-14-en-24-oic acid (4), and 16-oxolyclanitin-29-yl E-4\u2032-hydroxyl-3\u2032-methoxycinnamate (5) on the basis of their spectroscopic data as well as nine known analogs. \u00a9 2007 Elsevier Ltd. All rights reserved.",
        "keywords": [
            "Diphasiastrum complanatum",
            "Lycopodiaceae",
            "Polyhydroxylated derivatives",
            "Serratane triterpenoid"
        ],
        "venue": "Phytochemistry",
        "year": 2008,
        "id": "MZ5WkDIm"
    },
    "3EF7kJw1": {
        "authors": [
            {
                "name": "Jian-Chao Chen",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Lu Lu",
                "org": "Graduate School of the Chinese Academy of Sciences"
            },
            {
                "name": "Xian-Ming Zhang",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Zhong-Rong Li",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Ming-Hua Qiu",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            }
        ],
        "title": "Eight new cucurbitane glycosides, kuguaglycosides A-H, from the root of Momordica charantia L.",
        "abstract": "Eight new cucurbitane glycosides, kuguaglycosides A-H (1-8, resp.), together with five known analogues, 3\u03b2,23-dihydroxycucurbita-5,24-dien- 7\u03b2-yl \u03b2-d-glucopyranoside (9), karaviloside III (10), karaviloside V (11), karaviloside XI (12), and momordicoside K (13), were isolated from the root of Momordica charantia L. The structures of the new compounds were determined on the basis of spectroscopic and chemical methods. \u00a9 2008 Verlag Helvetica Chimica Acta AG.",
        "keywords": [
            ""
        ],
        "venue": "Helvetica Chimica Acta",
        "year": 2008,
        "id": "3EF7kJw1"
    },
    "CYYMBChU": {
        "authors": [
            {
                "name": "Lirong Sun",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Jian Yan",
                "org": "Graduate School"
            },
            {
                "name": "Yin Nian",
                "org": "Graduate School"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Hongjie Zhang",
                "org": "Department of Medicinal Chemistry and Pharmacognosy"
            },
            {
                "name": "Minghua Qiu",
                "org": "Graduate School"
            }
        ],
        "title": "New triterpene diglycosides from the rhizome of Cimifuga foetida",
        "abstract": "Five new 9,19-cycloartane triterpene diglycosides, which have been named cimiaceroside C (1), and cimifosides A-D (2-5) together with the known compounds cimiracemoside D (6), cimidahurine (7) and \u03b1-D-glucopyranosyl-l-\u03b2-D- fructofuranoside (8) were isolated from the rhizome of Cimicifuga foetida. The new triterpene diglycosides 1-5 were identified as cimiacerol-3-O-\u03b2-D- xylopyranosyl-(1\u2033\u21923\u2032)-\u03b2-D-xylopyranoside, 12\u03b2-hydroxycimigenol-3-O-\u03b2-D-xylopyranosyl-(1\u2033\u21923\u2032) -\u03b2-D-xylopyranoside, 25-O-acetylcimig- enol-3-O-\u03b2-D-xylopyranosyl- (1\u2033\u21923\u2032)-\u03b2-D-xylopyranoside, 24-acetylhydroshengmanol-3-O- \u03b2-D-xylopyranosyl-(1\u2033\u21923\u2032)-\u03b2-D-xylopyranoside and 26-deoxyacetylacteol-3-O-\u03b2-D-xylo- pyranosyl-(1\u2033\u21923\u2032)- \u03b2-D-xylopyranoside, respectively, based on analysis of their spectral data and chemical reactions. \u00a9 2008 by the authors; licensee Molecular Diversity Preservation International.",
        "keywords": [
            "Cimicifuga foetida",
            "Cimifosides",
            "Cycloartane triterpenoid",
            "Diglycosides"
        ],
        "venue": "Molecules",
        "year": 2008,
        "id": "CYYMBChU"
    },
    "8mdkjIP5": {
        "authors": [
            {
                "name": "Yin Nian",
                "org": "Graduate School"
            },
            {
                "name": "Jian-Chao Chen",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Lu Lu",
                "org": "Graduate School"
            },
            {
                "name": "Xian-Ming Zhang",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Ming-Hua Qiu",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            }
        ],
        "title": "Four new 9,19-cyclolanostane derivatives from the rhizomes of Cimicifuga yunnanensis hsiao",
        "abstract": "Four new 9,19-cyclolanostane-type triterpenes, 24-O-acetyl-25- anhydroshengmanol-3-O-\u03b2-d-xylopyranoside (1), 25-i-butylcimigenol-3-O- \u03b2-d-xylopyranoside (2), 12-\u03b2-hydrocimigenol-3-one (3), and 12-\u03b2-hydrocimigenol-1-en-3-one (4), together with 15 known analogues were isolated from the rhizome of Cimicifuga yunnanensis Hsiao. Their structures were determined by spectroscopic and chemical methods. \u00a9 2009 Verlag Helvetica Chimica Acta AG.",
        "keywords": [
            ""
        ],
        "venue": "Helvetica Chimica Acta",
        "year": 2009,
        "id": "8mdkjIP5"
    },
    "xx3V4Ejs": {
        "authors": [
            {
                "name": "Jian-Chao Chen",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Wu-Qing Liu",
                "org": "Laboratory of Molecular Immunopharmacology"
            },
            {
                "name": "Lu Lu",
                "org": "Graduate School"
            },
            {
                "name": "Ming-Hua Qiu",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Yong-Tang Zheng",
                "org": "Laboratory of Molecular Immunopharmacology"
            },
            {
                "name": "Liu-Meng Yang",
                "org": "Laboratory of Molecular Immunopharmacology"
            },
            {
                "name": "Xian-Min Zhang",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Zhong-Rong Li",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            }
        ],
        "title": "Kuguacins F-S, cucurbitane triterpenoids from Momordica charantia",
        "abstract": "Chemical investigation of the vines and leaves of Momordica charantia resulted in isolation of fourteen cucurbitane triterpenoids, kuguacins F-S (1-14), including two pentanorcucurbitacins (6 and 7), one octanorcucurbitacin (8), and two trinorcucurbitacins (11 and 12), along with six known analogues. Their structures were elucidated on the basis of extensive spectroscopic and single-crystal X-ray diffraction analyses. Compounds 1-14 exhibited weak anti-HIV-1 activities in vitro. \u00a9 2008 Elsevier Ltd. All rights reserved.",
        "keywords": [
            "Cucurbitaceae",
            "Cucurbitane triterpenoids",
            "Kuguacins F-S",
            "Momordica charantia"
        ],
        "venue": "Phytochemistry",
        "year": 2009,
        "id": "xx3V4Ejs"
    },
    "TXwivfM3": {
        "authors": [
            {
                "name": "Run-Bing Li",
                "org": "Graduate School"
            },
            {
                "name": "Lin Zhou",
                "org": "Graduate School"
            },
            {
                "name": "Jin Wang",
                "org": "Center for Cold Atom Physics"
            },
            {
                "name": "Ming-Sheng Zhan",
                "org": "Center for Cold Atom Physics"
            }
        ],
        "title": "Measurement of the quadratic Zeeman shift of ",
        "abstract": "We demonstrate a technique for directly measuring the quadratic Zeeman shift using stimulated Raman transitions. The quadratic Zeeman shift has been measured yielding \u0394 \u03bd = 1296.8 \u00b1 3.3 Hz/G",
        "keywords": [
            ""
        ],
        "venue": "Optics Communications",
        "year": 2009,
        "id": "TXwivfM3"
    },
    "YEaU1l7H": {
        "authors": [
            {
                "name": "Jin Wang",
                "org": "Center for Cold Atom Physics"
            },
            {
                "name": "Lin Zhou",
                "org": "Graduate School"
            },
            {
                "name": "Run-Bing Li",
                "org": "Graduate School"
            },
            {
                "name": "Min Liu",
                "org": "Center for Cold Atom Physics"
            },
            {
                "name": "Ming-Sheng Zhan",
                "org": "State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics"
            }
        ],
        "title": "Cold atom interferometers and their applications in precision measurements",
        "abstract": "Experimental realization of cold ",
        "keywords": [
            "Atom interferometer",
            "Cold atom",
            "Precision measurement"
        ],
        "venue": "Frontiers of Physics in China",
        "year": 2009,
        "id": "YEaU1l7H"
    },
    "RsDqKe5y": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Institute of Meteorology"
            },
            {
                "name": "Cheng-Yin Yang",
                "org": "Institute of Meteorology"
            },
            {
                "name": "Han-Jie Wang",
                "org": "Key Laboratory of Regional Climate-Environment Research for Temperate East Asia (RCE-TEA)"
            },
            {
                "name": "Su-Xuan Zhao",
                "org": "A Certain Army of Airforce"
            }
        ],
        "title": "Interpretation scheme of SST prediction in the tropical Pacific Ocean based on CCA-BP-BPNN",
        "abstract": "To improve the accuracy of short-term numerical SST prediction, a nonlinear interpretation model using full-scale information of the numerical products was proved to be effective in raising the accuracy of short-term SST prediction. Canonical variables were constituted using CCA-BP method which mainly represented covariance between factors and the predictive variables. The relativity between the new-formed composed factors and the predictive variables increased significantly, hence a nonlinear regression model was developed by BPNN method. The nonlinear interpretation scheme was used to establish the predictive equation for the SST prediction in the tropical Pacific Ocean in the test, and then a scheme for forecasting SST of each point in this region was proposed. The forecast experiment results indicate that the interpretation behaves perfectly well in ENSO forecasting, and the effective period of validity can reach more than one year. For the 6-year March SST prediction of each point in the tropical Pacific Ocean, the average absolute error is 0.22\u00b0C. This method offers a reference for interpretation prediction of SST.",
        "keywords": [
            "BPNN (back-propagation neural network)",
            "Canonical correlation",
            "ENSO (EI Nino suthern oscillation) prediction",
            "Interpretation",
            "SST (sea surface temperature) prediction"
        ],
        "venue": "Jiefangjun Ligong Daxue Xuebao/Journal of PLA University of Science and Technology (Natural Science Edition)",
        "year": 2009,
        "id": "RsDqKe5y"
    },
    "H1e3iRSh": {
        "authors": [
            {
                "name": "Zhen-Jie Li",
                "org": "Yunnan University of TCM"
            },
            {
                "name": "Jian-Chao Chen",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Yun Sun",
                "org": "Graduate School of Chinese Academy of Sciences"
            },
            {
                "name": "Na-Li Song",
                "org": "Yunnan University of TCM"
            },
            {
                "name": "Bao-Hui Chenga",
                "org": "Graduate School of Chinese Academy of Sciences"
            },
            {
                "name": "Lu Lu",
                "org": "Graduate School of Chinese Academy of Sciences"
            },
            {
                "name": "Wei-Guang Ma",
                "org": "Yunnan University of TCM"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Xian-Min Zhang",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Zhong-Rong Li",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Ming-Hua Qiu",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            }
        ],
        "title": "Three new triterpene saponins from Hemsleya chinensis",
        "abstract": "Three new triterpenoid saponins, xuedanglycosides A-C (1-3, resp.), along with six known ones, were isolated from the rhizomes of Hemsleya chinensis. By detailed analysis of the NMR spectra, by chemical methods, and by comparison with spectral data of known compounds, the structures of new compounds were determined to be 16\u03b1,23\u03b1-epoxy-2\u03b2,3\u03b1,20\u03b2-trihydroxy- 10\u03b1,23\u03b1-cucurbita-5,24-dien-11-on-2-yl \u03b2-D-glucopyranoside (1), 2\u03b2,3\u03b1,16\u03b1,20\u03b2-tetrahydroxycucurbita-5,25-diene-11,22- dion-2-yl \u03b2-D-glucopyranoside (2), and oleanolic acid 28-O-\u03b2- xylopyranosyl-(1\u21926)-O-\u03b2-glucopyranoside (3). In addition, hemslecin A 2-O-\u03b2-D-glucopyranoside (6), hemsamabilinin B (7), and hemslonin A (9) were obtained for the first time from this plant. \u00a9 2009 Verlag Helvetica Chimica Acta AG.",
        "keywords": [
            ""
        ],
        "venue": "Helvetica Chimica Acta",
        "year": 2009,
        "id": "H1e3iRSh"
    },
    "HxarHOUQ": {
        "authors": [
            {
                "name": "Jian Yan",
                "org": "South China Botanical Garden"
            },
            {
                "name": "Lirong Sun",
                "org": "School of Basic Medical Sciences"
            },
            {
                "name": "Guisheng Wu",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Ping Yi",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Fumei Yang",
                "org": "The Key Laboratory of Chemistry for Natural Products of Guizhou Province"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Xianmin Zhang",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Zhongrong Li",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Xiaosheng Yang",
                "org": "The Key Laboratory of Chemistry for Natural Products of Guizhou Province"
            },
            {
                "name": "Huairong Luo",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Minghua Qiu",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            }
        ],
        "title": "Rational design and synthesis of highly potent anti-acetylcholinesterase activity huperzine A derivatives",
        "abstract": "By targeting multi-active sites of acetylcholinesterase (AChE), a series of huperzine A (Hup A) derivatives with various aromatic ring groups were designed and synthesized by Schiff reaction. They were evaluated as AChE and butyrylcholinesterase (BChE) inhibitors. Results showed very significant specificity that the group of imine derivatives could inhibit TcAChE and hAChE, but no inhibitory effect on hBChE was detected. The experiment was explained by a docking study. In the docking model, we confirmed that aromatic ring of Hup A derivatives played the \u03c0-\u03c0 stacking against aminophenol residues of AChE, and the structure-activity relationship (SAR) was discussed. \u00a9 2009 Elsevier Ltd. All rights reserved.",
        "keywords": [
            "AChE",
            "Alzheimer's disease",
            "Docking study",
            "Hupzine A"
        ],
        "venue": "Bioorganic and Medicinal Chemistry",
        "year": 2009,
        "id": "HxarHOUQ"
    },
    "emA0cxnQ": {
        "authors": [
            {
                "name": "Li-Chun Ren",
                "org": "Graduate School"
            },
            {
                "name": "Lin Zhou",
                "org": "Graduate School"
            },
            {
                "name": "Run-Bing Li",
                "org": "Graduate School"
            },
            {
                "name": "Min Liu",
                "org": "Center for Cold Atom Physics"
            },
            {
                "name": "Jin Wang",
                "org": "Center for Cold Atom Physics"
            },
            {
                "name": "Ming-Sheng Zhan",
                "org": "Center for Cold Atom Physics"
            }
        ],
        "title": "Dependence of sensitivity of atom interferometer gravimeters on the Raman laser pulse sequences",
        "abstract": "We investigate the dependence of the sensitivity of atom interferometer gravimeter on the Raman laser pulse sequence. The sensitivity of atom gravimeter can be adjusted by changing the pulse duration. Under the standard pulse configuration condition, the atom interferometer with four pulses is insensitive to the gravity if only gravity and its first order gradient are taken into account. The three-pulse Raman atom interferometer gravimeter displays best sensitivity. Atom interferometers with more than four Raman pulses show poorer sensitivity. \u00a9 2009 Chin.Phys.Soc.",
        "keywords": [
            "Atom gravimeter",
            "Raman laser pulse sequence",
            "Sensitivity"
        ],
        "venue": "Wuli Xuebao/Acta Physica Sinica",
        "year": 2009,
        "id": "emA0cxnQ"
    },
    "xobKmFOx": {
        "authors": [
            {
                "name": "Jian Yan",
                "org": "South China Botanical Garden"
            },
            {
                "name": "Lirong Sun",
                "org": "School of Basic Medical Sciences"
            },
            {
                "name": "Xianming Zhang",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Zhongrong Li",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Minghua Qiu",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            }
        ],
        "title": "Serratene triterpenoids from Palhinhaea cernua var. sikkimensis",
        "abstract": "Seven new serratene triterpenoids, 3\u03b1,21\u03b2,29-trihydroxy-16- oxoserrat-14-en-24-oic acid (1), 3\u03b2,21\u03b2,29-trihydroxy-16-oxoserrat-14- en-24-oic acid (2), 3\u03b2,21\u03b2,29-trihydroxyserrat-14-en-24-oic acid 3\u03b2-(4-hydroxybenzoate) (3), 3\u03b2,21\u03b2,29-trihydroxyserrat-14-en-24- oic acid 3\u03b2-(4-hydroxy-3-methoxybenzoate) (4), 3\u03b2,14\u03b1,15\u03b1, -21\u03b2,29-pentahydroxyserrat-14-en-24-oic acid 3\u03b2-(4-hydroxybenzoate) (5), 3\u03b1,21\u03b2,24,29-tetrahydroxyserrat-14-en-16-one (6), 3\u03b1,21\u03b2,30-trihydroxyserrat-14-en-16-one (7) were isolated from Palhinhaea cernua var. sikkimensis, together with twelve known compounds (8-19). Their chemical structures were elucidated on the basis of spectroscopic evidence and comparison with literature values. \u00a9 2009 Pharmaceutical Society of Japan.",
        "keywords": [
            "Palhinhaea",
            "Serratene",
            "Triterpenoid"
        ],
        "venue": "Chemical and Pharmaceutical Bulletin",
        "year": 2009,
        "id": "xobKmFOx"
    },
    "YasMkfdT": {
        "authors": [
            {
                "name": "Hongtao Duan",
                "org": ""
            },
            {
                "name": "Ronghua Ma",
                "org": ""
            },
            {
                "name": "Yuanzhi Zhang",
                "org": ""
            },
            {
                "name": "Steven Arthur Loiselle",
                "org": ""
            },
            {
                "name": "Jingping Xu",
                "org": ""
            },
            {
                "name": "Chenlu Zhao",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Linlin Shang",
                "org": ""
            }
        ],
        "title": "A new three-band algorithm for estimating chlorophyll concentrations in turbid inland lakes",
        "abstract": "A new three-band model was developed to estimate chlorophyll-a concentrations in turbid inland waters. This model makes a number of important improvements with respect to the three-band model commonly used, including lower restrictions on wavelength optimization and the use of coefficients which represent specific inherent optical properties. Results showed that the new model provides a significantly higher determination coefficient and lower root mean squared error (RMSE) with respect to the original model for upwelling data from Taihu Lake, China. The new model was tested using simulated data for the MERIS and GOCI satellite systems, showing high correlations with the former and poorer correlations with the latter, principally due to the lack of a 709 nm centered waveband. The new model provides numerous advantages, making it a suitable alternative for chlorophyll-a estimations in turbid and eutrophic waters. \u00a9 2010 IOP Publishing Ltd.",
        "keywords": [
            "Absorption coefficient",
            "Bio-optical model",
            "Inherent optical properties",
            "Water color remote sensing"
        ],
        "venue": "Environmental Research Letters",
        "year": 2010,
        "id": "YasMkfdT"
    },
    "A4ubrs23": {
        "authors": [
            {
                "name": "Jian Yan",
                "org": "South China Botanical Garden"
            },
            {
                "name": "Lirong Sun",
                "org": "School of Basic Medical Sciences"
            },
            {
                "name": "Wei Li",
                "org": "Laboratory of Pharmaceutical Resources Discovery"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Zhongrong Li",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Xianmin Zhang",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Ling Yang",
                "org": "Laboratory of Pharmaceutical Resources Discovery"
            },
            {
                "name": "Minghua Qiu",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            }
        ],
        "title": "Cytotoxic serratane triterpenes from diphasiastrum complanatum with a Hydroxy group at C-27",
        "abstract": "Four serratane-type triterpenes (14) were isolated from D. complanatum. Their chemical structures were elucidated as 14,15,20,21,24,27,29- heptahydroxyserrat-3-one (1), 3,14,15,20,21,24,27,29-octahydroxyserratane (2), 3,14,20,21,24,27,29-heptahydroxyserratane (3) and 3,14,21,24,27-pentahydroxyl- serratane-29-yl (E)-p-coumarate (4) by spectroscopic methods (MS, 1D and 2DNMR) and Xray crystallography. Interestingly, the most characteristic methylene (C-27) of the serratane ring C was oxidized to a methine. Compound 4 showed significant cytotoxic activity against the human leukemia K562/S and the doxorubicin-resistant K562/R cell lines, but the other compounds were inactive. \u00a9 Georg Thieme Verlag KG Stuttgart - New York.",
        "keywords": [
            "Complanatumols AD",
            "Diphasiastrum complanatum",
            "Leukemia",
            "Lycopodiaceae",
            "Serratanetype"
        ],
        "venue": "Planta Medica",
        "year": 2010,
        "id": "A4ubrs23"
    },
    "a0kkhLev": {
        "authors": [
            {
                "name": "Xing-Tao Su",
                "org": "Institute of Meteorology"
            },
            {
                "name": "Han-Jie Wang",
                "org": "Key Laboratory of Regional Climate-Environment Research for Temperate East Asia"
            },
            {
                "name": "Lin Zhou",
                "org": "Institute of Meteorology"
            }
        ],
        "title": "Simulation on temporal and spatial distribution and direct radiative forcing of carbonaceous aerosols over China",
        "abstract": "To enhance understanding on the carbonaceous aerosols over China, aerosol data from International Center for Theoretical Physics (ICTP) and regional climate model RegCM3 were used to simulate the temporal and spatial distribution and radiative forcing of the carbonaceous aerosols in 2000. The preliminary results show that carbonaceous aerosols are mostly concentrated in the area of the south of Yellow River and the east of Tibetan Plateau. Referring to the seasonal variation characteristics, the simulation indicates that the maximum value of column burden of the carbonaceous aerosols appears in spring, the second value in winter and the minimum in summer. The radiative forcing of the carbonaceous aerosols is positive on the top of atmosphere (TOA) besides eastern littoral and negative on the ground. The complex mutual action exists in different kinds of aerosols, which indicates that experiments on the distribution and climate effects of aerosols should not add the effects of single aerosols.",
        "keywords": [
            "Carbonaceous aerosols",
            "Column burden",
            "Radiative forcing"
        ],
        "venue": "Jiefangjun Ligong Daxue Xuebao/Journal of PLA University of Science and Technology (Natural Science Edition)",
        "year": 2010,
        "id": "a0kkhLev"
    },
    "MkuoebCk": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Graduate University of the Chinese Academy of Sciences"
            },
            {
                "name": "Zong-Yuan Xiong",
                "org": "Graduate University of the Chinese Academy of Sciences"
            },
            {
                "name": "Wei Yang",
                "org": "Graduate University of the Chinese Academy of Sciences"
            },
            {
                "name": "Biao Tang",
                "org": "Graduate University of the Chinese Academy of Sciences"
            },
            {
                "name": "Wen-Cui Peng",
                "org": "Graduate University of the Chinese Academy of Sciences"
            },
            {
                "name": "Yi-Bo Wang",
                "org": "Graduate University of the Chinese Academy of Sciences"
            },
            {
                "name": "Peng Xu",
                "org": "Graduate University of the Chinese Academy of Sciences"
            },
            {
                "name": "Jin Wang",
                "org": "Center for Cold Atom Physics"
            },
            {
                "name": "Ming-Sheng Zhan",
                "org": "Center for Cold Atom Physics"
            }
        ],
        "title": "Measurement of local gravity via a cold atom interferometer",
        "abstract": "We demonstrate a precision measurement of local gravity acceleration 9 in Wuhan by a compact cold atom interferometer. The atom interferometer is in vertical Mach-Zehnder configuration realized using a \u03c0/2?\u03c0? \u03c0/2 Raman pulse sequence. Cold atoms were prepared in a magneto-optical trap, launched upward to form an atom fountain, and then coherently manipulated to interfere by stimulated Raman transition. Population signal vs Raman laser phase was recorded as interference fringes, and the local gravity was deduced from the interference signal. We have obtained a resolution of 7 \u00d7 10",
        "keywords": [
            ""
        ],
        "venue": "Chinese Physics Letters",
        "year": 2011,
        "id": "MkuoebCk"
    },
    "YwzHiyku": {
        "authors": [
            {
                "name": "Yu-Xin Yan",
                "org": "Graduate School of the Chinese Academy of Sciences"
            },
            {
                "name": "Yun Sun",
                "org": "Graduate School of the Chinese Academy of Sciences"
            },
            {
                "name": "Zhong-Rong Li",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Ming-Hua Qiu",
                "org": "Graduate School of the Chinese Academy of Sciences"
            }
        ],
        "title": "Chemistry and biological activities of Buxus alkaloids",
        "abstract": "Triterpenoid alkaloids are one of the most important classes that have been studied. Buxus alkaloids are such a type of triterpenoid alkaloids of cycloartenol skeleton with a degraded C-20 side chain, and with the nitrogen containing substituents at C-3 and/or C-20. 219 Buxus alkaloids have been reported so far. This review article focuses on the structural characters, plant sources and biological activities of Buxus alkaloids. This review includes anti-myocardial ischemia, inhibition of acetyl- and butyryl-cholinesterases, cytotoxicity and antibacterial activities. The biological activities, mechanisms and structure modifications of cyclovirobuxine D (CVB-D) are also described. \u00a9 2011 Bentham Science Publishers Ltd.",
        "keywords": [
            "Biological activity",
            "Buxaceae",
            "Buxus alkaloid",
            "Cyclovirobuxine D",
            "Structure modification"
        ],
        "venue": "Current Bioactive Compounds",
        "year": 2011,
        "id": "YwzHiyku"
    },
    "VZpIw6F0": {
        "authors": [
            {
                "name": "Man Ren",
                "org": "State Key Laboratory of Organic Geochemistry"
            },
            {
                "name": "Ping'an Peng",
                "org": "State Key Laboratory of Organic Geochemistry"
            },
            {
                "name": "Ying Cai",
                "org": "State Key Laboratory of Organic Geochemistry"
            },
            {
                "name": "Deyi Chen",
                "org": "State Key Laboratory of Organic Geochemistry"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Organic Geochemistry"
            },
            {
                "name": "Pei Chen",
                "org": "State Key Laboratory of Organic Geochemistry"
            },
            {
                "name": "Jianfang Hu",
                "org": "State Key Laboratory of Organic Geochemistry"
            }
        ],
        "title": "PBDD/F impurities in some commercial deca-BDE",
        "abstract": "The study presented the concentrations and distributions of polybrominated dibenzo-p-dioxins and polybrominated dibenzofurans (PBDD/Fs) as impurities in some commercial decabromodiphenyl ether (DBDE) mixtures that were produced by several manufacturers. The total concentrations of 12 2,3,7,8-substituted tetra- to octa-BDD/F congeners were found to be in the range of 3.4-13.6 (mean 7.8) \u03bcg/g, averagely accounting for 99% of total PBDD/Fs. OBDF was the prevailing congener, followed by 1,2,3,4,6,7,8-HpBDF. In addition, OBDD and 1,2,3,4,7,8-HxBDF were also obviously detectable. The total concentrations of PBDD/Fs varied both between the manufacturers and between the lots. On the basis of the global demand for the commercial DBDE in 2001, the annual potential emissions of PBDD/Fs were calculated coarsely to be 0.43 (range: 0.21-0.78) tons. The major dioxin congeners, OBDF and 1,2,3,4,6,7,8-HpBDF, presenting in DBDE, were estimated to be formed from BDE-209, BDE-206, and/or BDE-207 via an intra-molecular elimination of Br",
        "keywords": [
            "Brominated dioxins",
            "DBDE",
            "Formation mechanism",
            "Impurity"
        ],
        "venue": "Environmental Pollution",
        "year": 2011,
        "id": "VZpIw6F0"
    },
    "XLWnMG8g": {
        "authors": [
            {
                "name": "Hao Guan",
                "org": ""
            },
            {
                "name": "Han-Jie Wang",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Song Yang",
                "org": ""
            }
        ],
        "title": "A numerical simulation study on the typhoon-ocean interaction in the South China Sea",
        "abstract": "Based on the theory of atmosphere-current-wave interaction, a regional atmosphere-ocean coupling system is formed in this paper. The complicated air-sea interaction under typhoon condition in South China Sea is studied using the coupling system. The experiment results show that the coupled model exhibits good capability in simulating the typhoon process and improves the simulation accuracy of typhoon track and intensity. With the feedback mechanism of the top oceanic environmental factors such as SST, sea spray and waves, the simulated typhoon system in the coupled model is stronger and moves more leftward than that in the uncoupled atmospheric model. The three different air-sea interaction processes, sea surface temperature (SST) decline,the spray effect and ocean wave action, have different influence on the typhoon system. SST decline and ocean wave act to resist the development of typhoon, while sea spray acts in an opposite way, it enhances the typhoon development through the heat transfer at the sea surface. In the three processes, the influences of SST decline and sea spray are more important, the influence of wave is least. The impact of air-sea interaction on the development of typhoon system is not a linear summation of the three factors. There are complicate interaction mechanisms among the three. Our conclusion is that in order to better explain and predict the occurrence and evolution of the weather disasters such as typhoon and other severe weather events in South China Sea, all the air-sea interaction processes should be considered.",
        "keywords": [
            "Regional atmosphere-ocean coupled model",
            "Sea spray",
            "Sea surface roughness length",
            "Sea surface temperature",
            "Typhoon"
        ],
        "venue": "Chinese Journal of Geophysics (Acta Geophysica Sinica)",
        "year": 2011,
        "id": "XLWnMG8g"
    },
    "Wo0mbrzE": {
        "authors": [
            {
                "name": "Li-Rong Sun",
                "org": "Department of Neurobiology"
            },
            {
                "name": "Jian Yan",
                "org": "Key Laboratory of Plant Resources Conservation and Sustainable Utilization"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Zhong-Rong Li",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Ming-Hua Qiu",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            }
        ],
        "title": "Two new triterpene glycosides with monomethyl malonate groups from the rhizome of cimifuga foetida l.",
        "abstract": "Two new 9,19-cycloartane triterpene glycosides 1-2, together with four known compounds-26-deoxyactein (3), actein (4), 7,8-didehydro-26-deoxyactein (5) and cimiaceroside B (6)-were isolated from the rhizome of Cimicifuga foetida. The new triterpene glycosides were identified as 23-O-methyl-24-deoxy-2'-O-(3''- methylmalonyl)- cimiaceroside B (1) and 2'-O-(3''-methylmalonyl)actein (2) based on analysis of their spectral data and chemical reactions. \u00a9 2011 by the authors; licensee MDPI, Basel, Switzerland.",
        "keywords": [
            "Cimiaceroside",
            "Cimicifuga foetida",
            "Cimifoside",
            "Cycloartane triterpenoid"
        ],
        "venue": "Molecules",
        "year": 2011,
        "id": "Wo0mbrzE"
    },
    "C82hZ7Z6": {
        "authors": [
            {
                "name": "Yin Nian",
                "org": "Graduate School of the Chinese Academy of Sciences"
            },
            {
                "name": "Xian-Min Zhang",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Yan Li",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Yuan-Yuan Wang",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Jian-Chao Chen",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Lu Lu",
                "org": "Graduate School of the Chinese Academy of Sciences"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Ming-Hua Qiu",
                "org": "Graduate School of the Chinese Academy of Sciences"
            }
        ],
        "title": "Cycloartane triterpenoids from the aerial parts of Cimicifuga foetida Linnaeus",
        "abstract": "Cycloartane triterpenoids, 2\u2032,24-O-diacetylisodahurinol-3-O-\u03b1- l-arabinopyranoside, 24-O-acetylisodahurinol-3-O-\u03b1-l-arabinopyranoside, 12\u03b2-hydroxy-25-anhydrocimigenol, cimigenol-12-one, 12\u03b2-hydroxy-15- deoxycimigenol, 2\u2032-O-acetyl-24-epi-cimigenol-3-O-\u03b1-l- arabinopyranoside, 2\u2032-O-acetylcimigenol-3-O-\u03b2-d-xylopyranoside, 25-anhydrocimigenol-3-O-\u03b1-l-arabinopyranoside, 2\u2032,23-O- diacetylshengmanol-3-O-\u03b1-l-arabinopyranoside, and 2\u2032,24-O-diacetyl- 25-anhydrohydroshengmanol-3-O-\u03b1-l-arabinopyranoside, together with eight known compounds, were isolated from aerial parts of Cimicifuga foetida. Their structures were determined by application of spectroscopic analyses and chemical methods. Biological evaluation of the compounds against human HL-60, SMMC-7721, A549, SK-BR-3, and PANC-1 cell lines indicated that three of these compounds exhibited broad-spectrum and moderate cytotoxic activities, with IC",
        "keywords": [
            "Cimicifuga foetida",
            "Cycloartane triterpenoids",
            "Cytotoxicity",
            "Ranunculaceae",
            "Structure-activity relationships"
        ],
        "venue": "Phytochemistry",
        "year": 2011,
        "id": "C82hZ7Z6"
    },
    "ovql4JfE": {
        "authors": [
            {
                "name": "Huiru Li",
                "org": "State Key Laboratory of Organic Geochemistry"
            },
            {
                "name": "Lin Zhou",
                "org": "Graduate School of the Chinese Academy of Sciences"
            },
            {
                "name": "Ligui Mo",
                "org": "Graduate School of the Chinese Academy of Sciences"
            },
            {
                "name": "Ping'An Peng",
                "org": "State Key Laboratory of Organic Geochemistry"
            },
            {
                "name": "Guoying Sheng",
                "org": "State Key Laboratory of Organic Geochemistry"
            },
            {
                "name": "Jiamo Fu",
                "org": "State Key Laboratory of Organic Geochemistry"
            },
            {
                "name": "Zhiqiang Yu",
                "org": "State Key Laboratory of Organic Geochemistry"
            }
        ],
        "title": "Levels and congener profiles of particle-bound polybrominated dibenzo-p-dioxins/furans (PBDD/Fs) in ambient air around Guangzhou, China",
        "abstract": "The mean particulate polybrominated dibenzo-p-dioxins/furans (PBDD/Fs) levels for Guangzhou were in the range of 225-2244 fg/m ",
        "keywords": [
            "Brominated flame retardants",
            "Dioxins",
            "Furans",
            "Polybrominated diphenyl ethers"
        ],
        "venue": "Bulletin of Environmental Contamination and Toxicology",
        "year": 2011,
        "id": "ovql4JfE"
    },
    "2yHuqvlQ": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Jing Li",
                "org": ""
            },
            {
                "name": "Chong-Wei Zheng",
                "org": ""
            },
            {
                "name": "Xiao-Bin Chen",
                "org": ""
            }
        ],
        "title": "Wave energy research in global oceans with ERA-40 wave data for recent 45 years",
        "abstract": "This paper presents results from an investigation of global wave energy resources derived from analysis of ECMWF ERA-40 wave re-analysis data spanning the 45 year period from September 1957 to August 2002. The global distribution of wind sea energy and swell energy, based on the wave spectra partition, are presented for the first time. The spatial and temporal variations of the global wave energy, swell index, frequency of wave power grade and coefficient of variation are presented and described. By the criterion presented in this paper, the most energy-rich and exploitable areas of the global oceans are opened out. \u00a9 2011 IEEE.",
        "keywords": [
            "Assessment",
            "Criterion",
            "Global",
            "Swell energy",
            "Wave energy",
            "Wind sea energy"
        ],
        "venue": "2011 International Conference on Remote Sensing, Environment and Transportation Engineering, RSETE 2011 - Proceedings",
        "year": 2011,
        "id": "2yHuqvlQ"
    },
    "G7VEoJNF": {
        "authors": [
            {
                "name": "Man Ren",
                "org": "Research Center of the Pearl River Delta Environmental Pollution and Control"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Organic Geochemistry"
            },
            {
                "name": "Ping'An Peng",
                "org": "State Key Laboratory of Organic Geochemistry"
            },
            {
                "name": "De Yi Chen",
                "org": "State Key Laboratory of Organic Geochemistry"
            },
            {
                "name": "Ying Cai",
                "org": "Research Center of the Pearl River Delta Environmental Pollution and Control"
            }
        ],
        "title": "Atmospheric deposition of polybrominated dibenzo-p-dioxins and dibenzofurans in Guangzhou, China: Seasonal variations and sources",
        "abstract": "The atmospheric deposition of polybrominated dibenzo-p-dioxins and dibenzofurans (PBDD/Fs) was investigated at four locations in different suburban and urban functional districts of Guangzhou City. The annual deposition fluxes of total PBDD/Fs (eight 2,3,7,8-substituted tetra- to hexa-BDD/Fs) were in the range of 36-51 (mean 46) pg m ",
        "keywords": [
            ""
        ],
        "venue": "Journal of Environmental Monitoring",
        "year": 2011,
        "id": "G7VEoJNF"
    },
    "n5DBOI9F": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Graduate School of Chinese Acad. of Sci."
            },
            {
                "name": "Rong-Hua Ma",
                "org": "State Key Laboratory of Lake Science and Environment"
            },
            {
                "name": "Hong-Tao Duan",
                "org": "State Key Laboratory of Lake Science and Environment"
            },
            {
                "name": "Guang-Jia Jiang",
                "org": "Graduate School of Chinese Acad. of Sci."
            },
            {
                "name": "Lin-Lin Shang",
                "org": "Graduate School of Chinese Acad. of Sci."
            }
        ],
        "title": "Remote sensing retrieval for chlorophyll-a concentration in turbid case II waters(I): The optimal model",
        "abstract": "There is a little trouble to retrieve chlorophyll-a concentration (Chl-a) through remotely-sensed imageries in turbid waters, which contains many suspended sediments largely affecting the signature of water-leaving radiance due to phytoplankton pigment. Based on the in situ measurements during the period of 2004~2010, the two-band, three-band, enhanced three-band and four-band models were, respectively, regionally parameterized for the application in Tai Lake. Then the four parameterized models were validated by the in situ data in Chao Lake, almost the same water environment as in Tai Lake. The strongest linear relationship between Chl-a and the four-band model (R ",
        "keywords": [
            "Chlorophyll-a",
            "Remote sensing",
            "Semi-analytical model",
            "Turbid water"
        ],
        "venue": "Hongwai Yu Haomibo Xuebao/Journal of Infrared and Millimeter Waves",
        "year": 2011,
        "id": "n5DBOI9F"
    },
    "gRWY6zFO": {
        "authors": [
            {
                "name": "Yin Nian",
                "org": "Graduate School of the Chinese Academy of Sciences"
            },
            {
                "name": "Hai-Yan Wang",
                "org": "Graduate School of the Chinese Academy of Sciences"
            },
            {
                "name": "Jia Su",
                "org": "Graduate School of the Chinese Academy of Sciences"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Ming-Hua Qiu",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            }
        ],
        "title": "A cytotoxic 4\u03b1-methyl steroid from the aerial parts of Cimicifuga foetida L",
        "abstract": "A new 4\u03b1-methyl sterol, cimisterol A (1), together with five known compounds (2-6), were isolated from the aerial parts of Cimicifuga foetida L. The new compound's structure was determined with the help of extensive 1D and 2D NMR spectroscopy. Compound 1 exhibited broad-spectrum and potent cytotoxic activities against human HL-60, Jurkat, K562, U937, HepG-2, and SGC-7091 cell lines, with IC",
        "keywords": [
            "4\u03b1-methyl steroid",
            "Cimicifuga foetida",
            "Cimisterol A",
            "Cytotoxicity"
        ],
        "venue": "Fitoterapia",
        "year": 2012,
        "id": "gRWY6zFO"
    },
    "jAg0biKx": {
        "authors": [
            {
                "name": "Jie-Qing Liu",
                "org": ""
            },
            {
                "name": "Cui-Fang Wang",
                "org": ""
            },
            {
                "name": "Yan Li",
                "org": ""
            },
            {
                "name": "Jian-Chao Chen",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Ming-Hua Qiu",
                "org": ""
            }
        ],
        "title": "Limonoids from the leaves of Toona ciliata var. yunnanensis",
        "abstract": "Twelve limonoids, toonayunnanins A-L (1-12) and eleven known compounds (13-23) were isolated from the leaves of Toona ciliata var. yunnanensis, and their structures were elucidated by means of extensive spectroscopic analyses, particularly 1D and 2D NMR techniques. The inhibitory effects of all the isolated compounds were evaluated on human tumor cell lines, such as HL-60, SMMC-7721, A-549, MCF-7 and SW480. Cedrelone (13) and dysobinin (18) showed significant cytotoxicity, and toonayunnanin B (2) and epoxyazadiradione (14), were found to be slightly cytotoxic against the above cell lines. Furthermore, this study provides valuable information for the chemotaxonomy of T. ciliata varieties. \u00a9 2011 Elsevier Ltd. All rights reserved.",
        "keywords": [
            "Baeyer-villiger type oxidation",
            "Cytotoxic activities",
            "Limonoids",
            "Meliaceae",
            "Nortriterpenoid",
            "Toona ciliata",
            "Toona ciliata var. yunnanensis",
            "Toonayunnanins A-L"
        ],
        "venue": "Phytochemistry",
        "year": 2012,
        "id": "jAg0biKx"
    },
    "OcbS1fFv": {
        "authors": [
            {
                "name": "Jing-Wei Jin",
                "org": ""
            },
            {
                "name": "Hong-Tao Duan",
                "org": ""
            },
            {
                "name": "Chen-Lu Zhao",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Lin-Lin Shang",
                "org": ""
            },
            {
                "name": "Guang-Jia Jiang",
                "org": ""
            }
        ],
        "title": "Remote estimation of phytoplankton pigments in inland lake waters with algae",
        "abstract": "Based on in situ data in Chao Lake from October 15 ",
        "keywords": [
            "Bio-optical algorithm",
            "Chlorophyll",
            "Phycocyanin",
            "Pigments absorption"
        ],
        "venue": "Hongwai Yu Haomibo Xuebao/Journal of Infrared and Millimeter Waves",
        "year": 2012,
        "id": "OcbS1fFv"
    },
    "8ZDeR9Zk": {
        "authors": [
            {
                "name": "Haiyan Wang",
                "org": "Graduate University of Chinese Academy of Sciences"
            },
            {
                "name": "Yin Nian",
                "org": "Graduate University of Chinese Academy of Sciences"
            },
            {
                "name": "Chengyou Ma",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Jieqing Liu",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Yanbo Song",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Minghua Qiu",
                "org": "Graduate University of Chinese Academy of Sciences"
            }
        ],
        "title": "Four new 9,19-cyclolanostane triterpenes from the rhizomes of Cimicifuga foetida collected in Yulong",
        "abstract": "Four new 9,19-cyclolanostane-type triterpenes (1-4), were isolated from the rhizomes of Cimicifuga foetida. On the basis of spectroscopic analysis, their chemical structures were elucidated as 1,7-dien-cimigenol-3,12-dione (1), 1-en-cimigenol-3,11-dione (2), 11(-hydroxy-7-en-cimigenol-3-one (3), and (20R,24R)-24,25-epoxy-11(-hydroxy-7-en-9,19-cyclolanost-3,16,23-trione (4). \u00a9 2012 SIOC, CAS, Shanghai, & WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.",
        "keywords": [
            "Cimicifuga foetida",
            "cimigenolone",
            "cyclolanostane"
        ],
        "venue": "Chinese Journal of Chemistry",
        "year": 2012,
        "id": "8ZDeR9Zk"
    },
    "TQGdktdy": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Graduate School"
            },
            {
                "name": "Huiru Li",
                "org": "State Key Laboratory of Organic Geochemistry"
            },
            {
                "name": "Zhiqiang Yu",
                "org": "State Key Laboratory of Organic Geochemistry"
            },
            {
                "name": "Man Ren",
                "org": "State Key Laboratory of Organic Geochemistry"
            },
            {
                "name": "Xiangying Zeng",
                "org": "State Key Laboratory of Organic Geochemistry"
            },
            {
                "name": "Ping'An Peng",
                "org": "State Key Laboratory of Organic Geochemistry"
            },
            {
                "name": "Guoying Sheng",
                "org": "State Key Laboratory of Organic Geochemistry"
            },
            {
                "name": "Jiamo Fu",
                "org": "State Key Laboratory of Organic Geochemistry"
            }
        ],
        "title": "Chlorinated and brominated dibenzo-p-dioxins and dibenzofurans in surface sediment from Taihu Lake, China",
        "abstract": "Polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) and polybrominated dibenzo-p-dioxins and dibenzofurans (PBDD/Fs) in surface sediment samples from Taihu Lake - an important water supply of the Yangtze River Delta, China - were investigated in the present study. Concentrations of PCDD/Fs ranged from 0.91 to 4.8 pg TEQ g",
        "keywords": [
            ""
        ],
        "venue": "Journal of Environmental Monitoring",
        "year": 2012,
        "id": "TQGdktdy"
    },
    "cfA68EAC": {
        "authors": [
            {
                "name": "Yun Sun",
                "org": "Yunnan University of Traditional Chinese Medicine"
            },
            {
                "name": "Jin-Xiong Chen",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Jia Su",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Yan Li",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Ming-Hua Qiu",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            }
        ],
        "title": "Three new pregnane alkaloids from Veratrum taliense",
        "abstract": "Three new alkaloids, 3-O-acetylveralkamine (1), veralkamine 3-(\u03b2-D-glucopyranoside) (2), and 6,7-epoxyverdine (3), together with five known alkaloids, veramitaline, veralkamine (4), angeloylzygadenine, veratroylzygadenine, and veramiline 3-(\u03b2-D-glucopyranoside), were isolated from the whole plants of Veratrum taliense. Their structures were elucidated on the basis of spectroscopic analysis, and the NMR data of veralkamine (4) are given for the first time. In addition, the cytotoxic activities of all isolated compounds, except for veramitaline, were tested. Copyright \u00a9 2012 Verlag Helvetica Chimica Acta AG, Z\u00fcrich, Switzerland.",
        "keywords": [
            "6,7-Epoxyverdine",
            "Alkaloids",
            "Cytotoxic activity",
            "Veralkamine 3-(\u03b2- D -glucopyranoside)",
            "Veralkamine, 3-O-acetyl-",
            "Veratrum taliense"
        ],
        "venue": "Helvetica Chimica Acta",
        "year": 2012,
        "id": "cfA68EAC"
    },
    "em6LDOzu": {
        "authors": [
            {
                "name": "Jia-Wang Rao",
                "org": "Graduate University of Chinese Academy of Sciences"
            },
            {
                "name": "Rong-Hua Ma",
                "org": "Nanjing Institute of Limnology and Geography"
            },
            {
                "name": "Hong-Tao Duan",
                "org": "Nanjing Institute of Limnology and Geography"
            },
            {
                "name": "Guang-Jia Jiang",
                "org": "Graduate University of Chinese Academy of Sciences"
            },
            {
                "name": "Lin-Lin Shang",
                "org": "Graduate University of Chinese Academy of Sciences"
            },
            {
                "name": "Lin Zhou",
                "org": "Graduate University of Chinese Academy of Sciences"
            }
        ],
        "title": "Aerosol optical thickness of the atmospheric aerosol over Taihu Lake and its features: Results of in-site measurements",
        "abstract": "Based on the data measured in situ by an automatic sun tracking photometer (CE-318), the aerosol optical thickness (AOT) and the corresponding \u00c5ngstr\u00f6m coefficient \u03b1 of the atmospheric aerosol over Taihu Lake from November 2005 to October 2010 were collected. The results showed that high values of AOT over Taihu Lake were measured in summer (June to July) whereas low values were detected in autumn and winter (October to January). However, the low and high values of \u03b1 appeared in spring (March to April) and in autumn (September to November), respectively. The variations of AOT and \u03b1 over Taihu Lake may be related to weather patterns in this region. Based on the frequency distribution, AOT (500 nm) had only one peak value, with a maximum frequency of 0.4-0.6 and a yearly average value of 0.80, accounting for 26% of the total sample. Calculated from the mean AOT (500 nm), the solar radiation reduction was reduced by at least 50% by the atmospheric aerosol, resulting in more turbid atmosphere in this region and consequently heavy fog and haze. There were two peak values of the \u00c5ngstr\u00f6m coefficient \u03b1, with the maximum frequency ranging from 1.1-1.3 and 1.3-1.5 and a yearly average value of 1.17, accounting for 30% of the total sample. Significant variations were also observed in the daily average values of AOT (500 nm) and \u03b1, indicating the coexistence of different types of aerosols over Taihu Lake. The mean value of AOT (500 nm) declined when \u03b1 increased. To sum up, values of AOT (500 nm) over Taihu Lake changed greatly with time, and the aerosol should be classified as an urban-industrial aerosol.",
        "keywords": [
            "\u00c5ngstr\u00f6m coefficient",
            "Aerosol optical thickness",
            "CE-318",
            "Observational data",
            "Taihu Lake"
        ],
        "venue": "Huanjing Kexue/Environmental Science",
        "year": 2012,
        "id": "em6LDOzu"
    },
    "SA3LaZjG": {
        "authors": [
            {
                "name": "Chongwei Zheng",
                "org": "12 Unit"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Marine and Space"
            }
        ],
        "title": "Wave climate and wave energy analysis of the South China Sea in recent 10 years",
        "abstract": "The third-generation wave model WAVEWATCH-III was used to simulation the waves from the year 1999 to 2009 with wind input of QuikSCAT/NCEP re-analysis data in the South China Sea. The characteristics of wave climate and wave energy were analyzed, which could be used to guide the wave energy power generation, especially choosing the suitable site. The results showed that the wind field and wave field were influenced by monsoon obviously. The wind field and wave field have better corresponding relation in the South China Sea, especially in the north waters. There are close relationships between wind field and nino3 index, wave field and nino3 index in the South China Sea. The large area of extreme wind speed and extreme wave height mainly were located in the north waters of the South China Sea. The South China Sea is rich in wave energy resources, the annual average energy density is 4~20 kW/m, the frequency of energy density large than 2 kW/m is above 70% in most area, and variation coefficient in most waters is below 0.40, which is benefit for the development of wave energy resources.",
        "keywords": [
            "The South China Sea",
            "Wave climate",
            "Wave energy",
            "WAVEWATCH-III"
        ],
        "venue": "Taiyangneng Xuebao/Acta Energiae Solaris Sinica",
        "year": 2012,
        "id": "SA3LaZjG"
    },
    "kn2nbRPp": {
        "authors": [
            {
                "name": "Yin Nian",
                "org": "Graduate School"
            },
            {
                "name": "Hai-Yan Wang",
                "org": "Graduate School"
            },
            {
                "name": "Jia Su",
                "org": "Graduate School"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Gang Feng",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Yan Li",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Ming-Hua Qiu",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            }
        ],
        "title": "Cytotoxic cycloartane triterpenes from the roots of Cimicifuga heracleifolia",
        "abstract": "Phytochemical investigation on the roots of Cimicifuga heracleifolia afforded nine new 9,19-cycloartane triterpenes (1-9), along with seven known constituents (10-16). The new structures were elucidated by spectroscopic and chemical methods. Biological evaluation of the compounds against human HL-60, SMMC-7721, A549, MCF-7, and SW-480 cell lines indicated that eight cimigenol-type compounds (1-3, 5, 10-12, 14) showed different levels of cytotoxic activities, with IC ",
        "keywords": [
            "Cimicifuga heracleifolia",
            "Cycloartane triterpenes",
            "Cytotoxicity",
            "Structure-activity relationships"
        ],
        "venue": "Tetrahedron",
        "year": 2012,
        "id": "kn2nbRPp"
    },
    "le70dq3c": {
        "authors": [
            {
                "name": "Xing-Tao Su",
                "org": "Institute of Meteorology"
            },
            {
                "name": "Han-Jie Wang",
                "org": "Key Laboratory of Regional Climate-Environment Research for Temperate East Asia"
            },
            {
                "name": "Lin Zhou",
                "org": "Institute of Meteorology"
            }
        ],
        "title": "Simulation of spatio-temporal distribution characteristics and radiative forcing of organic carbon aerosols in China",
        "abstract": "The International Centre for Theoretical Physics (ICTP, Italy) Regional Climate Model version 3.0 (RegCM3) is used to simulate spatio-temporal distribution characteristics and radiative forcing (RF) of organic carbon (OC) aerosols in and around China. The preliminary simulation results show that OC aerosols are mostly concentrated in the area to the south of Yellow River and east of Tibetan Plateau. There is a decreasing trend of column burden of OC aerosols from south to north in China. The maximum value of column burden of OC aerosols is above 3 mg/m2 and located in the central and southern China, southeastern Tibet, and southwestern China's Yunnan, Guizhou, Sichuan provinces. The simulation on the seasonal variation shows that the maximum value of column burden of OC aerosols appears in winter and the secondary value is in spring and the minimum in summer. The RF of OC aerosols which varies seasonally is negative at the top of the atmosphere (TOA) and surface. The spatio-temporal characteristics of the RF of OC aerosols are basically consistent with that of IPCC, implying the high accuracy of the parameterization scheme for OC aerosols in RegCM3.",
        "keywords": [
            "Column burden",
            "Numerical simulation",
            "Organic carbon aerosols",
            "Radiative forcing",
            "RegCM3 model"
        ],
        "venue": "Journal of Tropical Meteorology",
        "year": 2012,
        "id": "le70dq3c"
    },
    "AKmNguUf": {
        "authors": [
            {
                "name": "Yin Nian",
                "org": "Graduate School of the Chinese Academy of Sciences"
            },
            {
                "name": "Hai-Yan Wang",
                "org": "Graduate School of the Chinese Academy of Sciences"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Jia Su",
                "org": "Graduate School of the Chinese Academy of Sciences"
            },
            {
                "name": "Yan Li",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Ming-Hua Qiu",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            }
        ],
        "title": "Cytotoxic cycloartane triterpenes of the traditional Chinese medicine \"shengmao\" (Cimicifuga dahurica)",
        "abstract": "Twelve new 9,19-cycloartane triterpenes (1-12), together with fourteen known compounds (13-26), were isolated from the roots of Cimicifuga dahurica. Their structures were determined by application of spectroscopic analyses and chemical methods. Biological evaluation of the compounds against human HL-60, SMMC-7721, A549, MCF-7, and SW-480 cell lines indicated that cimigenol-type glycosides (1-3, 19, and 20) showed broad-spectrum and moderate cytotoxicities, with ICvalues ranging from 4.2 to 14.5 \u03bcM. Meanwhile, cimigenol-type aglycones (6-8, 15, 16, and 18) exhibited broad-spectrum and week cytotoxicities, having ICvalues around 20 \u03bcM. In addition, the key points of the structure-activity relationships of aglycones with a cimigenol skeleton were discussed. \u00a9 Georg Thieme Verlag KG Stuttgart - New York.",
        "keywords": [
            "Cimicifuga dahurica",
            "cycloartane triterpenes",
            "cytotoxicity",
            "Ranunculaceae",
            "structure-activity relationships"
        ],
        "venue": "Planta Medica",
        "year": 2013,
        "id": "AKmNguUf"
    },
    "euiNDSpg": {
        "authors": [
            {
                "name": "Jian Shi",
                "org": "Institute of Meteorology"
            },
            {
                "name": "Lin Zhou",
                "org": "Institute of Meteorology"
            },
            {
                "name": "Long-Ying Yang",
                "org": "Institute of Meteorology"
            }
        ],
        "title": "Influence of sea spray droplets on drag coefficient in high wind speed",
        "abstract": "Sea spray droplets change the distribution of air-sea momentum fluxes in the sea surface, and then influence sea surface drag coefficient considerably. In order to estimate the influence of sea spray droplets on drag coefficient exactly, a new sea spray generation function (SSGF) which depends on wind and wave, is deduced. Then the SSGF is integrated into the spray momentum flux formula to calculate the spray momentum flux. The result shows that revised spray momentum flux formula are sensitive to the wave state remarkably. It indicates that the new sea spray flux formulae can be used in any wave state. The total momentum flux of sea surface contains sea spray momentum flux and air-sea interface momentum flux. Based on this theory, the formula of drag coefficient which is influenced by sea spray droplets at high wind speed is acquired. The theoretical result of the drag coefficient formula shows that the drag coefficient reduces at the high wind speed, which indicates that the sea spray droplets can restrict the increase of drag coefficient at high wind speed. Comparison between theoretical value and measured value of sea surface drag coefficient in field and laboratory shows that the theoretical value of drag coefficient cover the measured value almost. Meanwhile, with the new sea surface drag coefficient, ocean wave model can model the significant wave height very well in typhoon condition. All the results show that the new drag coefficient can be used properly at high wind speed. \u00a9 2013 Chinese Physical Society.",
        "keywords": [
            "Drag coefficient",
            "Sea spray",
            "Wave state"
        ],
        "venue": "Wuli Xuebao/Acta Physica Sinica",
        "year": 2013,
        "id": "euiNDSpg"
    },
    "x1zvRF4F": {
        "authors": [
            {
                "name": "Bao-Hui Cheng",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Jian-Chao Chen",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Jie-Qing Liu",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Ming-Hua Qiu",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            }
        ],
        "title": "Cucurbitane-type triterpenoids from Momordica charantia",
        "abstract": "The six new cucurbitane-type triterpenoids 1-6, along with the ten known triterpenoids 7-16, were isolated from the vines and leaves of Momordica charantia. The structures of the new compounds were elucidated as (3\u03b2,7\u03b2,15\u03b2,23E)-3,7,15,25-tetrahydroxycucurbita-5,23-dien-19-al (1), (3\u03b2,7\u03b2)-3,7,22,23-tetrahydroxycucurbita-5,24-dien-19-al (2), (3\u03b2,7\u03b2)-3,7,23,24-tetrahydroxycucurbita-5,25-dien-19-al (3), (3\u03b2,7\u03b2,23S)-3,7,23-trihydroxycucurbita-5,24-dien-19-al 7-\u03b2-D-glucopyranoside (4), (3\u03b2,7\u03b2,23E)-cucurbita-5,23-diene-3,7, 19,25-tetrol 7-\u03b2-D-glucopyranoside (5), and (3\u03b2,7\u03b2,23E)-3,7- dihydroxy-25-methoxy-cucurbita-5,23-dien-19-al 3-\u03b2-D-allopyranoside (6), by extensive analyses of their spectral data, as well as by chemical methods. Copyright \u00a9 2013 Verlag Helvetica Chimica Acta AG, Z\u00fcrich.",
        "keywords": [
            "Cucurbitanes",
            "Momordica charantia",
            "Triterpenes"
        ],
        "venue": "Helvetica Chimica Acta",
        "year": 2013,
        "id": "x1zvRF4F"
    },
    "1nfLpFjD": {
        "authors": [
            {
                "name": "Guang-Jia Jiang",
                "org": "State Key Laboratory of Lake Science and Environment"
            },
            {
                "name": "Lin Zhou",
                "org": "Graduate University of Chinese Academy of Sciences"
            },
            {
                "name": "Rong-Hua Ma",
                "org": "State Key Laboratory of Lake Science and Environment"
            },
            {
                "name": "Hong-Tao Duan",
                "org": "State Key Laboratory of Lake Science and Environment"
            },
            {
                "name": "Lin-Lin Shang",
                "org": "Graduate University of Chinese Academy of Sciences"
            },
            {
                "name": "Jia-Wang Rao",
                "org": "Graduate University of Chinese Academy of Sciences"
            },
            {
                "name": "Chen-Lu Zhao",
                "org": "Graduate University of Chinese Academy of Sciences"
            }
        ],
        "title": "Remote sensing retrieval for chlorophyll-a concentration in turbid case II waters (II): Application on MERIS image",
        "abstract": "Based on four filed cruises from 2004 to 2010 in Tai Lake, four models were investigated in the present study, including two-ration-model (TRM), three-band-model (TBM), enhanced three-band-model (ETM) and four-band model (FBM) using in situ measurements and MERIS image data. The validation was performed using samples from Taihu (n=13) and Chaohu Lake (n=21). The results demonstrated that the ETM was the most appropriate to estimate chlorophyll a concentration in highly turbid waters with higher R",
        "keywords": [
            "Chlorophyll a",
            "Inland waters",
            "Specific absorption coefficient",
            "Tai Lake"
        ],
        "venue": "Hongwai Yu Haomibo Xuebao/Journal of Infrared and Millimeter Waves",
        "year": 2013,
        "id": "1nfLpFjD"
    },
    "hyyv7Wuv": {
        "authors": [
            {
                "name": "Jie-Qing Liu",
                "org": ""
            },
            {
                "name": "Yuan-Feng Yang",
                "org": ""
            },
            {
                "name": "Xu-Yang Li",
                "org": ""
            },
            {
                "name": "En-Qian Liu",
                "org": ""
            },
            {
                "name": "Zhong-Rong Li",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Yan Li",
                "org": ""
            },
            {
                "name": "Ming-Hua Qiu",
                "org": ""
            }
        ],
        "title": "Cytotoxicity of naturally occurring rhamnofolane diterpenes from Jatropha curcas",
        "abstract": "Twelve rhamnofolane diterpenoids, including curcusecons A-E with unusual seco-rhamnofolane skeletons, curcusones F-J, 4-epi-curcusone E, and 3-dehydroxy-2-epi-caniojane, together with seven known analogues, curcusones A-E, jatrogrossidione, and 2-epi-jatrogrossidione, were isolated from the roots of Jatropha curcas. Their structures were determined by extensive spectroscopic methods, and the relative stereochemistry of curcusecon B was further confirmed by X-ray crystallographic data. Their cytotoxity against five human cancer cells was studied and the results indicated that the dienone system in ring B was essential for cytotoxicity of these compounds.\u00a9 2013 Elsevier Ltd. All rights reserved.",
        "keywords": [
            "Cytotoxicity",
            "Euphorbiaceae",
            "Jatropha curcas",
            "Rhamnofolane diterpenoids"
        ],
        "venue": "Phytochemistry",
        "year": 2013,
        "id": "hyyv7Wuv"
    },
    "5I9U3w0h": {
        "authors": [
            {
                "name": "Chongwei Zheng",
                "org": "Meteorological Unit"
            },
            {
                "name": "Lin Zhou",
                "org": "College of Meteorology and Oceanography"
            },
            {
                "name": "Chaofan Huang",
                "org": "College of Meteorology and Oceanography"
            },
            {
                "name": "Yinglong Shi",
                "org": "College of Meteorology and Oceanography"
            },
            {
                "name": "Jiaxun Li",
                "org": "College of Meteorology and Oceanography"
            },
            {
                "name": "Jing Li",
                "org": "College of Meteorology and Oceanography"
            }
        ],
        "title": "The long-termtrend of the sea surface wind speed and the wave height (wind wave, swell, mixed wave) in global ocean during the last 44 a",
        "abstract": "Utilizing the 45 a European Centre for Medium-Range Weather Forecasts (ECMWF) reanalysis wave data (ERA-40), the long-term trend of the sea surface wind speed and (wind wave, swell, mixed wave) wave height in the global ocean at grid point 1.5\u00b0 \u00d71.5\u00b0 during the last 44 a is analyzed. It is discovered that a majority of global ocean swell wave height exhibits a significant linear increasing trend (2-8 cm/decade), the distribution of annual linear trend of the significant wave height (SWH) has good consistency with that of the swell wave height. The sea surface wind speed shows an annually linear increasing trend mainly concentrated in the most waters of Southern Hemisphere westerlies, high latitude of the North Pacific, Indian Ocean north of 30\u00b0 S, the waters near the western equatorial Pacific and low latitudes of the Atlantic waters, and the annually linear decreasing mainly in central and eastern equator of the Pacific, Juan. Fernandez Archipelago, the waters near South Georgia Island in the Atlantic waters. The linear variational distribution characteristic of the wind wave height is similar to that of the sea surface wind speed. Another find is that the swell is dominant in themixed wave, the swell index in the central ocean is generally greater than that in the offshore, and the swell index in the eastern ocean coast is greater than that in thewestern ocean inshore, and in year-round hemisphere westerlies the swell index is relatively low. \u00a9 2013 The Chinese Society of Oceanography and Springer-Verlag Berlin Heidelberg.",
        "keywords": [
            "ECMWF reanalysis wave data",
            "long-termtrend",
            "mixed wave",
            "swell",
            "swell index",
            "wind wave"
        ],
        "venue": "Acta Oceanologica Sinica",
        "year": 2013,
        "id": "5I9U3w0h"
    },
    "t6pOreFI": {
        "authors": [
            {
                "name": "Hao Guan",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Yan-Guang Xue",
                "org": ""
            },
            {
                "name": "Yang Zhang",
                "org": ""
            }
        ],
        "title": "Applied study on atmosphere-ocean-wave coupled model in south China sea",
        "abstract": "Based on MM5, POM, and WW3, a regional atmosphere-ocean-wave coupled system is developed in this work under the environment of Message Passing Interface. The coupled system is applied in a study of two typhoon processes in the South China Sea (SCS). The results show that the coupled model operates steadily and efficiently and exhibits good capability in simulating typhoon processes. It improves the simulation accuracy of the track and intensity of the typhoon. The response of ocean surface to the typhoon is remarkable, especially on the right side of the typhoon track. The sea surface temperature (SST) declines, and the ocean current and wave height are intensified. In the coupling experiment, the decline of SST intensifies and the inertial oscillation amplitude of the ocean current increases when the ocean-wave effect is considered. Therefore, the atmosphere-ocean-wave coupled system can help in the study of air-sea interaction and improve the capability of predicting and preventing weather and oceanic disasters in SCS.",
        "keywords": [
            "Atmosphere-ocean-wave coupled model",
            "Feedback of ocean",
            "Numerical simulation study",
            "Ocean-wave effect",
            "Typhoon"
        ],
        "venue": "Journal of Tropical Meteorology",
        "year": 2013,
        "id": "t6pOreFI"
    },
    "ZHGGQclx": {
        "authors": [
            {
                "name": "Gao-Ting Zhao",
                "org": "Faculty of Life Science and Technology, Kunming University of Science and Technology"
            },
            {
                "name": "Jie-Qing Liu",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences"
            },
            {
                "name": "Yuan-Yuan Deng",
                "org": "University of Chinese Academy of Science"
            },
            {
                "name": "Hai-Zhou Li",
                "org": "Faculty of Life Science and Technology, Kunming University of Science and Technology"
            },
            {
                "name": "Jian-Chao Chen",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences"
            },
            {
                "name": "Zhi-Run Zhang",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences"
            },
            {
                "name": "Ming-Hua Qiu",
                "org": "University of Chinese Academy of Science"
            }
        ],
        "title": "Cucurbitane-type triterpenoids from the stems and leaves of Momordica charantia",
        "abstract": "Six new cucurbitane-type triterpenoids, karavilagenin F (1), karavilosides XII and XIII (2, 3), momordicines VI, VII, and VIII (4, 5 and 6), along with four known ones, 5\u03b2,19-epoxy-25-methoxycucurbita-6,23-diene-3\u03b2,19-diol (7), 5\u03b2,19-epoxycucurbita-6, 23-diene-3\u03b2,19,25-triol (8), kuguacin R (9), and (19R,23E)-5\u03b2,19-epoxy-19-methoxycucurbita-6,23,25-trien-3\u03b2-ol (10), were isolated from the stems and leaves of Momordica charantia L. Their chemical structures were elucidated by extensive 1D NMR and 2D NMR (HSQC, HMBC, COSY, and ROESY), MS experiments, and CD spectrum. Compound 6 showed weak cytotoxicity against five human cancer cells lines with IC",
        "keywords": [
            "Cucurbitaceae",
            "Cucurbitane-type triterpenoids",
            "Cytotoxicity",
            "Momordica charantia"
        ],
        "venue": "Fitoterapia",
        "year": 2014,
        "id": "ZHGGQclx"
    },
    "KoHQI64a": {
        "authors": [
            {
                "name": "Huiru Li",
                "org": "State Key Laboratory of Organic Geochemistry, Guangdong Key Laboratory of Environment and Resources, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences"
            },
            {
                "name": "Lin Zhou",
                "org": "Graduate School of the Chinese Academy of Sciences"
            },
            {
                "name": "Man Ren",
                "org": "State Key Laboratory of Organic Geochemistry, Guangdong Key Laboratory of Environment and Resources, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences"
            },
            {
                "name": "Guoying Sheng",
                "org": "State Key Laboratory of Organic Geochemistry, Guangdong Key Laboratory of Environment and Resources, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences"
            },
            {
                "name": "Jiamo Fu",
                "org": "State Key Laboratory of Organic Geochemistry, Guangdong Key Laboratory of Environment and Resources, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences"
            },
            {
                "name": "Ping'an Peng",
                "org": "State Key Laboratory of Organic Geochemistry, Guangdong Key Laboratory of Environment and Resources, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences"
            }
        ],
        "title": "Levels, profiles and gas-particle distribution of atmospheric PCDD/Fs in vehicle parking lots of a South China metropolitan area",
        "abstract": "Vehicle exhaust is one important PCDD/F source in urban areas. In this study, occurrence and inhalation of atmospheric PCDD/Fs in three enclosed/semi-enclosed large-scale vehicle parks were investigated. The park for heavy-duty diesel-trucks exhibited the highest atmospheric 2,3,7,8-PCDD/F concentrations (17.7\u00b14.3pgm",
        "keywords": [
            "Doxins and furans",
            "Heavy-duty diesel-trucks",
            "Liquefied petroleum gas (LPG)",
            "Persistent organic pollutants (POPs)",
            "Vehicle exhaust"
        ],
        "venue": "Chemosphere",
        "year": 2014,
        "id": "KoHQI64a"
    },
    "rZ6n13Te": {
        "authors": [
            {
                "name": "Yi Shu",
                "org": "School of Biotechnology and Food Engineering, Hefei University of Technology"
            },
            {
                "name": "Jie-Qing Liu",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences"
            },
            {
                "name": "Xing-Rong Peng",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences"
            },
            {
                "name": "Luo-Sheng Wan",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences"
            },
            {
                "name": "Tao Zhang",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences"
            },
            {
                "name": "Ming-Hua Qiu",
                "org": "School of Biotechnology and Food Engineering, Hefei University of Technology"
            }
        ],
        "title": "Characterization of diterpenoid glucosides in roasted puer coffee beans",
        "abstract": "Five new diterpenoid glucosides, named mascaroside I (1), mascaroside II (2), paniculoside VI (3), cofaryloside I (4), and villanovane I (5), along with seven known ent-kaurane diterpenoid glucosides (6-12) were isolated from acetone extracts of the roasted coffee beans of Coffea arabica var. yunnanensis. Their structures were established by extensive spectroscopic analysis including 1D and 2D NMR (HSQC, HMBC, COSY, and ROESY) and by comparison with published data. Cytotoxicities evaluation of the isolates showed that they were inactive against HL-60, SMMC-7721, A-549, MCF-7, and SW480 cells. \u00a9 2014 American Chemical Society.",
        "keywords": [
            "Coffea arabica var. yunnanensis",
            "cytotoxicities",
            "diterpenoids",
            "roasted coffee beans",
            "structural elucidation"
        ],
        "venue": "Journal of Agricultural and Food Chemistry",
        "year": 2014,
        "id": "rZ6n13Te"
    },
    "yDh7jCFn": {
        "authors": [
            {
                "name": "Xing-Rong Peng",
                "org": ""
            },
            {
                "name": "Jie-Qing Liu",
                "org": ""
            },
            {
                "name": "Cui-Fang Wang",
                "org": ""
            },
            {
                "name": "Xu-Yang Li",
                "org": ""
            },
            {
                "name": "Yi Shu",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Ming-Hua Qiu",
                "org": ""
            }
        ],
        "title": "Hepatoprotective effects of triterpenoids from ganoderma cochlear",
        "abstract": "Two novel trinorlanostanes, cochlates A and B (1 and 2), with a 3,4-seco-9,10-seco-9,19-cyclo skeleton, as well as six new triterpenoids, fornicatins D-F (3-5) and ganodercochlearins A-C (6-8), together with five known triterpenoids (9-13), were obtained from the fruiting bodies of Ganoderma cochlear. The structural elucidation was achieved by interpretation of spectroscopic data, and compounds 2 and 7a were further characterized by X-ray crystallographic analysis. Fornicatins A, D, and F (10, 3, and 5) and fredelin (13) lowered the ALT and AST levels in HepG2 cells treated with H ",
        "keywords": [
            ""
        ],
        "venue": "Journal of Natural Products",
        "year": 2014,
        "id": "yDh7jCFn"
    },
    "gd8gM9ig": {
        "authors": [
            {
                "name": "Ni-Man Bao",
                "org": ""
            },
            {
                "name": "Yin Nian",
                "org": ""
            },
            {
                "name": "Guo-Lei Zhu",
                "org": ""
            },
            {
                "name": "Wei-Hua Wang",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Ming-Hua Qiu",
                "org": ""
            }
        ],
        "title": "Cytotoxic 9,19-cycloartane triterpenes from the aerial parts of Cimicifuga yunnanensis",
        "abstract": "Six new 9,19-cycloartane triterpenes (1-6) were isolated from the aerial parts of Cimicifuga yunnanensis. The new chemical structures were determined by extensive analyses of 1D and 2D NMR spectroscopy. Compounds 1 and 2 are the first 9,19-cycloartane triterpenes characterized by CH",
        "keywords": [
            "18(13\u219212)Abeo-9 19-cycloartane",
            "Cimicifuga yunnanensis",
            "Cytotoxicity",
            "triterpenes"
        ],
        "venue": "Fitoterapia",
        "year": 2014,
        "id": "gd8gM9ig"
    },
    "d82CVndB": {
        "authors": [
            {
                "name": "Jian-Chao Chen",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences"
            },
            {
                "name": "Xiao-Xi Yuan",
                "org": "Graduate University, Chinese Academy of Sciences"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences"
            },
            {
                "name": "Jie-Qing Liu",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences"
            },
            {
                "name": "Yin Nian",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences"
            },
            {
                "name": "Zhong-Rong Li",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences"
            },
            {
                "name": "Yan Li",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences"
            },
            {
                "name": "Ming-Jin Xie",
                "org": "School of Chemical Science and Technology, Yunnan University"
            },
            {
                "name": "Ming-Hua Qiu",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences"
            }
        ],
        "title": "Four new cucurbitacins from the fruit of momordica charantia",
        "abstract": "Four new 5\u03b2,19-epoxycucurbitacins, kuguacins T-W (1 - 4, resp.), along with nine known cucurbitane derivatives, 5 - 13, were obtained from the fresh fruit of Momordica chrantia. Structures of the new metabolites were elucidated as 5\u03b2,19-epoxy-25-hydroxycucurbitane-3,7,23-trione (1), 5\u03b2,19-epoxy-3,7-dioxo-23,24,25,26,27-pentanorcucurbitan-22-oic acid (2), 5\u03b2,19-epoxy-3\u03b2-hydroxycucurbit-24-ene-7,23-dione (3), and 5\u03b2,19-epoxy-25-hydroxycucurbit-23-ene-3,7-dione (4), by extensive spectroscopic investigations, which were confirmed by a single-crystal X-ray diffraction analyses in the case of compound 4.",
        "keywords": [
            ""
        ],
        "venue": "Helvetica Chimica Acta",
        "year": 2014,
        "id": "d82CVndB"
    },
    "qsPc2FBb": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "China Jiliang University"
            },
            {
                "name": "Xiaoling Peng",
                "org": "China Jiliang University"
            },
            {
                "name": "Xinqing Wang",
                "org": "China Jiliang University"
            },
            {
                "name": "Hongliang Ge",
                "org": "China Jiliang University"
            },
            {
                "name": "Jing Zhang",
                "org": "Hangzhou University of Electronic Science and Technology"
            },
            {
                "name": "Yunwei Xu",
                "org": "Zhejiang Thermal Power Construction Company"
            }
        ],
        "title": "Preparation and characterization of manganese-zinc ferrites by a solvothermal method",
        "abstract": "Manganese-zinc ferrites (Mn-Zn ferrites) nanocomposites were prepared by a solvothermal method and characterized by X-ray Diffraction,scanning electronic microscope and vibrating sample magnetometer. Effects of different factors, including the ratio of Mn<sup>2+</sup> to Zn<sup>2+</sup>, the temperature and time of solvothermal reaction on the magnetic properties and microstructures of Mn-Zn ferrites were investigated. Results demonstrate that with the rising of reaction time, the particle size becomes bigger and more stable, and the saturation magnetization of the Mn-Zn ferrites nanocomposites increases; when the temperature are 160 and 180 \u00b0C, no Mn-Zn ferrites are formed for the temperatures are too low, and the formation temperature of Mn-Zn ferrites spherical particles is 200 \u00b0C; rising of Mn<sup>2+</sup> concentration can not change the morphology of Mn-Zn ferrites, but will contribute to increasing of the saturation magnetization and decreasing of the coercivity of products obtained.",
        "keywords": [
            "Magnetic property",
            "Microstructures",
            "Mn-Zn ferrites",
            "Morphology",
            "Solvothermal method"
        ],
        "venue": "Xiyou Jinshu Cailiao Yu Gongcheng/Rare Metal Materials and Engineering",
        "year": 2015,
        "id": "qsPc2FBb"
    },
    "vteu0Eeg": {
        "authors": [
            {
                "name": "Qian-Qian Shi",
                "org": "Laboratory of Tree Breeding and Cultivation, Research Institute of Forestry, Chinese Academy of Forestry"
            },
            {
                "name": "Lin Zhou",
                "org": "Laboratory of Tree Breeding and Cultivation, Research Institute of Forestry, Chinese Academy of Forestry"
            },
            {
                "name": "Kui Li",
                "org": "Laboratory of Tree Breeding and Cultivation, Research Institute of Forestry, Chinese Academy of Forestry"
            },
            {
                "name": "Yan Wang",
                "org": "Laboratory of Tree Breeding and Cultivation, Research Institute of Forestry, Chinese Academy of Forestry"
            }
        ],
        "title": "Isolation and expression of PlbHLH3 transcription factor genes in Paeonia lutea",
        "abstract": "Twenty-four unigene sequences shared high homology with bHLH transcription factor protein involved in plant anthocyanin biosynthesis were obtained from previous-constructed tree peony (Paeonia lutea) petal transcriptome database and named as PlbHLH1~24. By amino acid sequence comparing and phylogenetic tree analysis, it showed that PlbHLH3 was considered to be related to regulate anthocyanin biosynthesis, contained a 2 040 bp ORF encoding 679 amino acid residues with typical bHLH structural domain; the predicted protein sequence of PlbHLH3 also shared high similarity with other bHLH transcription factor that related to anthocyanin biosynthesis such as VvMYC1 and MdbHLH3. Relative Real-Time PCR analysis indicated that PlbHLH3 expressed in different tissues of P. lutea and P. delavayi, the expression in carpel, anther and petal was significantly higher than that in sepal and leaf; PlbHLH3 reached the highest abundance at early stage of P. lutea,. For P. delavayi, the PlbHLH3 reached the lowest level at early stage, and was significantly or extremely significantly lower than that in other four stages. In conclusion, it is inferred that PlbHLH3 might associate with the regulatory of anthocyanin biosynthesis in P. lutea and this would provide the basis for insight into the molecular mechanisms underlying tree peony yellow flower pigmentation.",
        "keywords": [
            "Anthocyanin biosynthesis",
            "BHLH",
            "Expression analysis",
            "Gene cloning",
            "Paeonia lutea"
        ],
        "venue": "Forest Research",
        "year": 2015,
        "id": "vteu0Eeg"
    },
    "C9CIg04K": {
        "authors": [
            {
                "name": "Yukang Han",
                "org": "College of Meteorology and Oceanography, PLA Univ. of Sci. & Tech."
            },
            {
                "name": "Lin Zhou",
                "org": "College of Meteorology and Oceanography, PLA Univ. of Sci. & Tech."
            }
        ],
        "title": "Analysis of acoustic field in tropical Indian Ocean upper based on Argo data",
        "abstract": "For an in-depth knowledge of the underwater acoustic field in the tropical Indian Ocean, a relatively comprehensive research and analysis is made, including the horizontal distribution and vertical cross-section distribution of underwater sound, the distribution of acoustic spring layer, the seasonal variation and the vertical structure by the use of the Argo (Array for Real-time Geostrophic Oceanography)data from 2004 to 2013 and in accordance with the empirical formula offered by Chen and Millero for sound velocity calculation. In addition, the strong spring layer was researched month by month. The result shows that the 50-meter-deep acoustic velocity field distributs in annuluses broadwise, high in the north and low in the south, while the 200-meter-deep acoustic velocity field distributes in the form of upland-bottomland-upland-bottomland from north to south. On the fracture surface at 85\u00b0E, there are larger trough and ridge for acoustic velocity isogram to the south of the equator while there is flat and straight land to the north; and acoustic spring layer generally distributes shallowly in south and deeply in north in winter. There are some visible deep regions in the Western Indian Ocean at 10\u00b0N and the Eastern Indian Ocean at 10\u00b0S. The thickness of spring layer is usually larger in winter than in summer and larger in the east than in the west, and there is a high value area for the distribution of the layer intensity in winter and two high value areas in summer. About the cross-section distribution of the layer, its structure, intensity and position change significantly from season to season.",
        "keywords": [
            "Acoustic field",
            "Argo",
            "The tropical Indian Ocean"
        ],
        "venue": "Jiefangjun Ligong Daxue Xuebao/Journal of PLA University of Science and Technology (Natural Science Edition)",
        "year": 2015,
        "id": "C9CIg04K"
    },
    "1GegTKxF": {
        "authors": [
            {
                "name": "Na-Li Song",
                "org": "Yunnan Institute of Traditional Chinese Medicine and Materia Medica"
            },
            {
                "name": "Zhen-Jie Li",
                "org": "Key Laboratory of Medicinal Chemistry for Nature Resource, School of Chemical Science and Technology, Yunnan University"
            },
            {
                "name": "Jian-Chao Chen",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences"
            },
            {
                "name": "Yuan-Yuan Deng",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences"
            },
            {
                "name": "Mu-Yuan Yu",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences"
            },
            {
                "name": "Ming-Hua Qiu",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences"
            }
        ],
        "title": "Two new penterpenoid saponins and a new diterpenoid glycoside from Hemsleya chinensis",
        "abstract": "Two new penterpenoid saponins, hemsloside-Ma4 (1) hemsloside-Ma5 (2), and a new diterpenoid glycoside, hemsloside-Ma6 (3), were isolated from the rhizomes of Hemsleya chinensis. By detailed analysis of the NMR spectra and chemical methods, the structures of new compounds were determined to be 3-O-\u03b2-l-arabinopyranosyl-(1 \u2192 3)-O-(6\u2032-methyl ester)-\u03b2-d-glucuropyranosyl-oleanolic acid-28-O-\u03b2-d-glucopyranosyl-(1 \u2192 6)-O-\u03b2-d-glucopyranoside (1), 3-O-\u03b2-l-arabinopyranosyl-(1 \u2192 3)-O-(6\u2032-methyl ester)-\u03b2-d-glucuropyranosyl-oleanolic acid-28-O-\u03b2-d-xylopyranosyl-(1 \u2192 6)-O-\u03b2-d-glucopy-ranoside (2), and 13\u03b5-hydroxylabda-8(17), 14-dien-18-oic acid-18-O-\u03b1-l-rhamnopyranosyl-(1 \u2192 2)-O-\u03b2-d-glucopyranosyl-(1 \u2192 4)-O-\u03b1-l-rhamnopyranoside (3). Diterpenoid-type compound (3) was isolated from Hemsleya genus for the first time.",
        "keywords": [
            "Diterpenoid glycoside",
            "Hemsleya chinensis",
            "Triterpenoid sponin"
        ],
        "venue": "Phytochemistry Letters",
        "year": 2015,
        "id": "1GegTKxF"
    },
    "Uku3hHVO": {
        "authors": [
            {
                "name": "Qianqian Shi",
                "org": "State Key Laboratory of Tree Genetics and Breeding, Key Laboratory of Tree Breeding and Cultivation of State Forestry Administration, Research Institute of Forestry, Chinese Academy of Forestry"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Tree Genetics and Breeding, Key Laboratory of Tree Breeding and Cultivation of State Forestry Administration, Research Institute of Forestry, Chinese Academy of Forestry"
            },
            {
                "name": "Yan Wang",
                "org": "State Key Laboratory of Tree Genetics and Breeding, Key Laboratory of Tree Breeding and Cultivation of State Forestry Administration, Research Institute of Forestry, Chinese Academy of Forestry"
            },
            {
                "name": "Kui Li",
                "org": "State Key Laboratory of Tree Genetics and Breeding, Key Laboratory of Tree Breeding and Cultivation of State Forestry Administration, Research Institute of Forestry, Chinese Academy of Forestry"
            },
            {
                "name": "Baoqiang Zheng",
                "org": "State Key Laboratory of Tree Genetics and Breeding, Key Laboratory of Tree Breeding and Cultivation of State Forestry Administration, Research Institute of Forestry, Chinese Academy of Forestry"
            },
            {
                "name": "Kun Miao",
                "org": "State Key Laboratory of Tree Genetics and Breeding, Key Laboratory of Tree Breeding and Cultivation of State Forestry Administration, Research Institute of Forestry, Chinese Academy of Forestry"
            }
        ],
        "title": "Transcriptomic analysis of Paeonia delavayi wild population flowers to identify differentially expressed genes involved in purple-red and yellow petal pigmentation",
        "abstract": "Tree peony (Paeonia suffruticosa Andrews) is a very famous traditional ornamental plant in China. P. delavayi is a species endemic to Southwest China that has aroused great interest from researchers as a precious genetic resource for flower color breeding. However, the current understanding of the molecular mechanisms of flower pigmentation in this plant is limited, hindering the genetic engineering of novel flower color in tree peonies. In this study, we conducted a large-scale transcriptome analysis based on Illumina HiSeq sequencing of cDNA libraries generated from yellow and purple-red P. delavayi petals. A total of 90,202 unigenes were obtained by de novo assembly, with an average length of 721 nt. Using Blastx, 44,811 unigenes (49.68%) were found to have significant similarity to accessions in the NR, NT, and Swiss-Prot databases. We also examined COG, GO and KEGG annotations to better understand the functions of these unigenes. Further analysis of the two digital transcriptomes revealed that 6,855 unigenes were differentially expressed between yellow and purple-red flower petals, with 3,430 up-regulated and 3,425 down-regulated. According to the RNA-Seq data and qRT-PCR analysis, we proposed that four up-regulated key structural genes, including F3H, DFR, ANS and 3GT, might play an important role in purple-red petal pigmentation, while high co-expression of THC2'GT, CHI and FNS II ensures the accumulation of pigments contributing to the yellow color. We also found 50 differentially expressed transcription factors that might be involved in flavonoid biosynthesis. This study is the first to report genetic information for P. delavayi. The large number of gene sequences produced by transcriptome sequencing and the candidate genes identified using pathway mapping and expression profiles will provide a valuable resource for future association studies aimed at better understanding the molecular mechanisms underlying flower pigmentation in tree peonies.",
        "keywords": [
            ""
        ],
        "venue": "PLoS ONE",
        "year": 2015,
        "id": "Uku3hHVO"
    },
    "hurMCdUe": {
        "authors": [
            {
                "name": "Xiong Du",
                "org": "Sch. of Elec. Eng."
            },
            {
                "name": "Luo-Wei Zhou",
                "org": "Lab. of High Voltage Eng."
            },
            {
                "name": "Pin-Fang Xie",
                "org": "Sch. of Elec. Eng."
            },
            {
                "name": "Lin Zhou",
                "org": "Sch. of Elec. Eng."
            }
        ],
        "title": "Improved one cycle controlled DC side active power filter and research on steady-state and dynamics",
        "abstract": "This paper proposes an improved DC side active power filter (APF) with one cycle control. The proposed DC side active power filter is shunted at the DC side of the bridge rectifier to compensate the reactive and harmonic current for the rectifier load. In contrast to power factor correction (PFC), DC side APF is connected in parallel with the nonlinear load. Therefore, DC side APF provides only the harmonic and reactive current. In this case only a small portion of the energy is processed, which may result in overall higher energy efficiency and higher power processing capability. Compared with the typical shunt APF, for which there is four power switches needed, the DC side APF only two active power switches are needed without adding the switch voltage and current stress. By using one cycle control, the control circuit is simple and robust which can be realized without multipliers, but simple analog circuits. And the steady and dynamic analyze of the control method is given, the result shows that not only the compensation property is enhanced, but also the stability region is broaden through the improved control method. All the findings are supported by experimental and simulation results.",
        "keywords": [
            "Active power filter",
            "DC side",
            "One cycle control",
            "Power electronics"
        ],
        "venue": "Zhongguo Dianji Gongcheng Xuebao/Proceedings of the Chinese Society of Electrical Engineering",
        "year": 2003,
        "id": "hurMCdUe"
    },
    "JHPNFMix": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of High Voltage Engineering and Electrical New Technology"
            },
            {
                "name": "Xiaoli Shen",
                "org": "Key Laboratory of High Voltage Engineering and Electrical New Technology"
            },
            {
                "name": "Luowei Zhou",
                "org": "Key Laboratory of High Voltage Engineering and Electrical New Technology"
            },
            {
                "name": "Peng Lei",
                "org": "Key Laboratory of High Voltage Engineering and Electrical New Technology"
            }
        ],
        "title": "Active power filter based on ip -iq detecting method and One-cycle control",
        "abstract": "As one-cycle controlled active power filter (APF) only can compensate harmonics and reactive currents simultaneously, this paper presents a scheme which uses i",
        "keywords": [
            ""
        ],
        "venue": "IECON Proceedings (Industrial Electronics Conference)",
        "year": 2004,
        "id": "JHPNFMix"
    },
    "yXtPBpwS": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of High Voltage Engineering and Electrical New Technology"
            },
            {
                "name": "Xiaojun Zhou",
                "org": "Key Laboratory of High Voltage Engineering and Electrical New Technology"
            },
            {
                "name": "Luowei Zhou",
                "org": "Key Laboratory of High Voltage Engineering and Electrical New Technology"
            },
            {
                "name": "Heng-Ming Tai",
                "org": "Department of Electrical Engineering"
            }
        ],
        "title": "One-cycle control for three-phase four-leg active power filter",
        "abstract": "This paper presents a three-phase four-leg active power filter design based on one-cycle control. We extend the constant-frequency integration control method to three-phase four-wire systems. The control circuit is composed of four integrators with reset along with several flip-flops, comparators and some linear components. The proposed APF does not require load current and phase voltage sensing, nor the harmonics and reactive current calculation, and does not use any multipliers. Moreover, it employs constant switching frequency modulation, which is desirable for industrial applications. Simulation results demonstrate that the proposed active power filter is capable of compensating current harmonics and reactive power, and reducing the neutral current in an effective and robust manner. \u00a9 2004 IEEE.",
        "keywords": [
            ""
        ],
        "venue": "IECON Proceedings (Industrial Electronics Conference)",
        "year": 2004,
        "id": "yXtPBpwS"
    },
    "CxgGIVKo": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Xiaoli Shen",
                "org": ""
            },
            {
                "name": "Luowei Zhou",
                "org": ""
            },
            {
                "name": "Peng Lei",
                "org": ""
            }
        ],
        "title": "Unified constant-frequency Integration control of four-arm three-phase four-wire Active Power Filter with vector operation",
        "abstract": "This paper presents a Unified constant-frequency Integration (UCI) control for a three-phase four-wire Active Power Filter (APF) with vector operation. Using this method only AC mains current and zero voltage crossing point are sensed. No sensors for the load current and the APF inductor current are required. Furthermore, there is no need to calculate the reference for APF inductor current so that complicated digital computation is eliminated. Three-phase unity-power -factor and low THD are achieved by integration with reset along with a few logic and linear components. And the amount of switching are operated at high frequency reduced, thus, the switching losses is optimized. In this paper analysis and simulation are carried out with the four-arm inverter, the simulation results verifed that the APF with UCI control can effectually compensate the harmonics, reactive current and zero sequence current. \u00a9 2004 IEEE.",
        "keywords": [
            ""
        ],
        "venue": "IECON Proceedings (Industrial Electronics Conference)",
        "year": 2004,
        "id": "CxgGIVKo"
    },
    "F1Cykjog": {
        "authors": [
            {
                "name": "Yun-Jie Wan",
                "org": "Key Laboratory of High Voltage Engineering and Electrical New Technology"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of High Voltage Engineering and Electrical New Technology"
            },
            {
                "name": "Hai Zhang",
                "org": "Key Laboratory of High Voltage Engineering and Electrical New Technology"
            },
            {
                "name": "Xue Xia",
                "org": "Key Laboratory of High Voltage Engineering and Electrical New Technology"
            }
        ],
        "title": "Control schemes of active power filter using digital signal processor",
        "abstract": "Active power filter (APF) is an important equipment to compensate harmonic and reactive currents in power systems and the key problem of the effective compensation lies in the real-time and accurate control. Because digital signal processor (DSP) possesses the advantage of high operation speed and can provide accurate calculation results, so it can meet such requirement of various APF control schemes as real-time and accurate calculation and fast response, and also can effectively improve the accuracy of control system. The authors present fundamental principles of several APF control schemes based on DSP such as space vector modulation, hysteresis current control, monocyclic control, slide mode control, dead beat control, repetitive control, predictive control and ANN based control, and the respective merit and demerit of these control method are pointed out.",
        "keywords": [
            "Active power filter",
            "Control scheme",
            "Digital signal processor",
            "Power electronics",
            "Power system"
        ],
        "venue": "Power System Technology",
        "year": 2005,
        "id": "F1Cykjog"
    },
    "csN49wNJ": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Yuanxing Gan",
                "org": ""
            },
            {
                "name": "Peng Lei",
                "org": ""
            },
            {
                "name": "Li Zhou",
                "org": ""
            }
        ],
        "title": "Novel harmonics detecting methods based on the instantaneous reactive power theory",
        "keywords": [
            "Detecting precision",
            "Instantaneous reactive power theory",
            "Real-time nature"
        ],
        "venue": "Gaodianya Jishu/High Voltage Engineering",
        "year": 2005,
        "id": "csN49wNJ"
    },
    "pGE7y2Pe": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "High Voltage Engineering and Electrical New Technology Key Laboratory of the Education Ministry"
            },
            {
                "name": "Li Zhou",
                "org": "High Voltage Engineering and Electrical New Technology Key Laboratory of the Education Ministry"
            }
        ],
        "title": "Three-level three-phase three-wire active power filter with one-cycle control",
        "keywords": [
            "Active power filter",
            "One-cycle control",
            "Three-level",
            "Three-phase three-wire"
        ],
        "venue": "Gaodianya Jishu/High Voltage Engineering",
        "year": 2005,
        "id": "pGE7y2Pe"
    },
    "1hEc5s8v": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Chongqing University"
            },
            {
                "name": "Xue Xia",
                "org": "Southwest Electric Power Design Institute"
            },
            {
                "name": "Yunjie Wan",
                "org": "The Architectural Design and Research Institute of Guangdong Province"
            },
            {
                "name": "Hai Zhang",
                "org": "Chongqing University"
            },
            {
                "name": "Peng Lei",
                "org": "Chongqing University"
            }
        ],
        "title": "Harmonic detection based on wavelet transform",
        "abstract": "Because of the ability of analyzing transient signal, wavelet transform is being used in the field of harmonic detection and the analysis of power quality. According to the internal and overseas actualities, the harmonic detection methods based on MALLAT arithmetic, wavelet packet, continuous wavelet transform, complex wavelet transform and adaptive wavelet are classified and summarized, and their advantages and disadvantages are analyzed and compared. The wavelet aliasing and virtual instrument based on wavelet transform for the analysis of power quality are discussed. Some problems that need to be solved of wavelet transform are summarized. At last, some opinions of the developing trend of wavelet transform in the use of harmonic detection are put forward.",
        "keywords": [
            "Harmonic detection",
            "Power quality",
            "Virtual instrument",
            "Wavelet transform"
        ],
        "venue": "Diangong Jishu Xuebao/Transactions of China Electrotechnical Society",
        "year": 2006,
        "id": "1hEc5s8v"
    },
    "HP1RFQBT": {
        "authors": [
            {
                "name": "Zhi-Xiang Xu",
                "org": "Key Laboratory of High Voltage Engineering and Electrical New Technology"
            },
            {
                "name": "Shi-Ying Hou",
                "org": "Key Laboratory of High Voltage Engineering and Electrical New Technology"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of High Voltage Engineering and Electrical New Technology"
            },
            {
                "name": "Hou-Yu Lu",
                "org": "Key Laboratory of High Voltage Engineering and Electrical New Technology"
            }
        ],
        "title": "Power system harmonic state estimation based on singular value decomposition",
        "abstract": "Traditional and advanced LSE (Least Squares Estimation) methods are mostly to measure harmonics asynchronously and then to solve the giant overdetermined linear equations, which has low estimation accuracy, tremendous calculations and measurements, and high cost. A harmonic state estimation method based on synchronous phasor measurements is presented, and ill-conditioned linear equations with complex variables are solved by the CSVD (Complex Singular Value Decomposition), which makes the estimation still effective when the system is partial observable and reduces the measurement redundancy degree. Taking the IEEE 30-bus system as an example, branch harmonic currents and bus harmonic voltages are synchronously measured with phasor measurement units. Simulations are carried out with Matlab and the SVD-based LSE program respectively. Results show that the harmonic state estimation based on SVD reflects the system harmonic state more accurately.",
        "keywords": [
            "Harmonic",
            "Singular value decomposition",
            "Synchronous phasor measurement unit",
            "The least square estimation"
        ],
        "venue": "Dianli Zidonghua Shebei / Electric Power Automation Equipment",
        "year": 2006,
        "id": "HP1RFQBT"
    },
    "jCUi6WI9": {
        "authors": [
            {
                "name": "Peng Lei",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Li Zhou",
                "org": ""
            },
            {
                "name": "Yun-Jie Wan",
                "org": ""
            },
            {
                "name": "Hai Zhang",
                "org": ""
            },
            {
                "name": "Xue Xia",
                "org": ""
            }
        ],
        "title": "Three-level three-phase four-wire active power filter based on one-cycle control",
        "keywords": [
            "3-phase 4-wire",
            "Active power filter",
            "One-cycle control",
            "Three-level"
        ],
        "venue": "Dianli Zidonghua Shebei / Electric Power Automation Equipment",
        "year": 2007,
        "id": "jCUi6WI9"
    },
    "K8syMcpq": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of High Voltage and Electrical New Technology"
            },
            {
                "name": "Xue Xia",
                "org": "Southwest Electric Power Design Institute"
            },
            {
                "name": "Yun-Jie Wan",
                "org": "Architectural Design and Research Institute of Guangdong Province"
            },
            {
                "name": "Hai Zhang",
                "org": "Key Laboratory of High Voltage and Electrical New Technology"
            },
            {
                "name": "Peng Lei",
                "org": "Key Laboratory of High Voltage and Electrical New Technology"
            }
        ],
        "title": "Harmonic measurement of three-phase asymmetrical system based on wavelet transform",
        "abstract": "Wavelet is a tool of digital signal processing and plays an important part in harmonic measurement of power system. However, because of the effect of the negative sequence of fundamental frequency signal and the limit of the frequency division of wavelet, wavelet transform is restricted in the use of harmonic measurement of three-phase dissymmetrical system. A new approach of harmonic measurement based on Period-interleaving of MALLAT arithmetic for dissymmetrical system is put forward in this paper. According to the characteristics of sine and cosine of three-phase dissymmetrical current after 3/2 transformation and the phase difference between 1/4 period, the negative sequence of fundamental frequency is counteracted by 1/4 period interleaving, then the positive sequence of fundamental frequency can be separated from the signals of high frequency by MALLAT arithmetic. The principle and the formula of this new method is put forward. To prove the new method of harmonic measurement based on MALLAT arithmetic, the method is programmed by assembly languages, and an actual three-phase asymmetrical system and a measurement system based on TMS320LF2407 digital signal processor is established. The experimental results reveal that the proposed method based on period-interleaving could overcome the limit of wavelet in the use of harmonic measurement of three-phase asymmetrical system and detect the positive sequence of fundamental frequency, then the total harmonics are detected.",
        "keywords": [
            "Harmonic measurement",
            "MALLAT arithmetic",
            "Period-interleaving",
            "Positive sequence of fundamental frequency",
            "Three-phase asymmetrical",
            "Wavelet transform"
        ],
        "venue": "Gaodianya Jishu/High Voltage Engineering",
        "year": 2007,
        "id": "K8syMcpq"
    },
    "kZ0PKeQ1": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of High Voltage and Electrical New Technology"
            },
            {
                "name": "Hua Zhuang",
                "org": "Key Laboratory of High Voltage and Electrical New Technology"
            },
            {
                "name": "Feng Zhang",
                "org": "Key Laboratory of High Voltage and Electrical New Technology"
            },
            {
                "name": "Qiu-Hua Li",
                "org": "Key Laboratory of High Voltage and Electrical New Technology"
            }
        ],
        "title": "Study on control method of three-phase APF",
        "abstract": "With the wide application of nonlinear equipment, a great amount of harmonic and reactive currents are generated in power system. Active power filter (APF) is one kind of power electronic devices used to restrain harmonics and compensate reactive power dynamically. It has advantages such as fast response, high control ability and adaptability. So the research on APF is more and more in many countries. One-cycle control (OCC) is a nonlinear control method, its principle is to control the duty-ratio of switch to make the average value of switch variable of the switching converter equal to or proportional to the control reference in each cycle, so that steady-state and dynamic-state errors can be eliminated effectively. Nowadays, OCC has been applied successfully, which displays fast response, excellent power source perturbation rejection and simple control circuit, but it only can compensate harmonics and reactive currents simultaneously. In fact, APF is more used to eliminate harmonics, but compensating harmonics and reactive power simultaneously is in the next place. In order to solve the disadvantages of one-cycle controlled APF, this paper uses an i",
        "keywords": [
            "Active power filter",
            "Flexible compensation",
            "Harmonics",
            "Ip-iq method",
            "One-cycle control method",
            "Reactive currents"
        ],
        "venue": "Gaodianya Jishu/High Voltage Engineering",
        "year": 2007,
        "id": "kZ0PKeQ1"
    },
    "8kYWZqzu": {
        "authors": [
            {
                "name": "Yun-Jie Wan",
                "org": "Key Laboratory of High Voltage and Electrical New Technology, Ministry of Education"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of High Voltage and Electrical New Technology, Ministry of Education"
            },
            {
                "name": "Hai Zhang",
                "org": "Mianyang Electric Power Company"
            },
            {
                "name": "Xue Xia",
                "org": "Southwest Electric Power Design Institute"
            },
            {
                "name": "Peng Lei",
                "org": "Key Laboratory of High Voltage and Electrical New Technology, Ministry of Education"
            }
        ],
        "title": "Development and application of one-cycle control",
        "abstract": "The one-cycle control (OCC) is a novel large-signal nonlinear control scheme with significant advantages of fast dynamic response, excellent power source anti-interference, robust performance, and automatic switching error elimination. It takes advantages of the pulsed and nonlinear nature of switching converters and achieves instantaneous dynamic control of the average value of a switched variable; more specifically the average value of the switched variable can reach a new steady-state after a transient in one switching cycle. There is no steady-state error or dynamic error between the control reference and the average value of the switched variable. One-cycle control is developed to dynamically control the duty-ratio d of a switch, so that in each cycle the average value of the switched variable at the switch output is exactly equal to or proportional to the control reference. One-cycle control restricts power source perturbations in one switching cycle; the average value of the switched variable follows the dynamic reference in one switching cycle; and the controller eliminations switching errors in one switching cycle. OCC's core component-the reset integrator is used to control the pulse width of an ac-dc converter, so it is more realizable than other nonlinear control methods. In this paper, new development of one-cycle control is discussed, which includes the feasibility, modeling, steady state and dynamic performance study as well as some improvement in one-cycle control. The application of one-cycle control to DC/DC converter, power factor correction (PFC), active power filter (APF), uninterruptible power supply (UPS), power amplifier and maximum power point tracking controller for photovoltaic power generation is introduced. Finally, the future development of one-cycle control is discussed.",
        "keywords": [
            "Active power filter",
            "One-cycle control",
            "Power amplifier",
            "Power electronics converter",
            "Pulse width modulation",
            "Uninterruptible power supply"
        ],
        "venue": "Gaodianya Jishu/High Voltage Engineering",
        "year": 2007,
        "id": "8kYWZqzu"
    },
    "H53382ND": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Feng Zhang",
                "org": ""
            },
            {
                "name": "Qiu-Hua Li",
                "org": ""
            },
            {
                "name": "Xiao-Fei Du",
                "org": ""
            },
            {
                "name": "Ming Xu",
                "org": ""
            },
            {
                "name": "Wei Wang",
                "org": ""
            }
        ],
        "title": "Methods for localizing the harmonic source in power distribution network",
        "abstract": "Electronics devices are nonlinear and thus they create distorted currents even supplied with purely sinusoidal voltage. Correct identification of harmonic source locations is essential for determining the responsibility mitigation means and for determining the responsibility of the parties involved. For the harmonic detection and harmonic control, the detection and localization of harmonic source at the point of common coupling (PCC) become more and more important. Since proposing the incentive scheme, many researchers put forward many localization methods. This article summarizes the methods of identifying the harmonic source including the Power-Direction Method and harmonic impedance method, and points out that the power direction method is theoretically incorrect and should not be used to determine harmonic source locations. The Neural-Network-Based Signature Recognition method and reference impedance method are introduced, and the advantages and disadvantages of the methods are presented. It is indicated that combination of artificial neural networks and fuzzy methods should be researched for the circuit analysis of electrical power systems. The necessity to propose an incentive-based scheme for limiting the harmonic pollution is presented. At last authors summarize the direction of this research, the key of the localization the harmonic source is to establish the uniform standard and applied in project. It is found that there are still many unsolved problems in this field.",
        "keywords": [
            "Equivalent model",
            "Harmonic contributions",
            "Harmonic impendence",
            "Harmonic power",
            "Harmonic source location",
            "Power quality"
        ],
        "venue": "Gaodianya Jishu/High Voltage Engineering",
        "year": 2007,
        "id": "H53382ND"
    },
    "DDwIt3yC": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of High Voltage and Electrical New Technology"
            },
            {
                "name": "Feng Zhang",
                "org": "Key Laboratory of High Voltage and Electrical New Technology"
            },
            {
                "name": "Qiu-Hua Li",
                "org": "Key Laboratory of High Voltage and Electrical New Technology"
            },
            {
                "name": "Ming Xu",
                "org": "Key Laboratory of High Voltage and Electrical New Technology"
            },
            {
                "name": "Wei Wang",
                "org": "Key Laboratory of High Voltage and Electrical New Technology"
            }
        ],
        "title": "New algorithm for random harmonic current detection using ip-iq without phase lock loop",
        "abstract": "In order to detect the random harmonic and eliminate the harm of harmonic to the power system, this paper put forward a new detection method based on the instantaneous reactive power theory without phase lock loop (PLL). This new method can detect positive and negative sequence components of random harmonic current respectively under three-phase asymmetrical system which is not influenced by voltage and can be applied to unbalanced load current, then the detected positive, negative phase sequences can be summed up to obtain the random harmonic current. In the new method, the transfer matrix is replaced by a fixed value because of the error will be eliminated. The new detecting harmonic current method gets rid of the PLL circuit, the benefit of the new method without PLL circuit is apparent. It not only saves the cost but also gives the more precision results. Theoretical analysis show that in the i",
        "keywords": [
            "Current detection",
            "Instantaneous reactive power theory",
            "Method of harmonic current detection based on ip-iq principle",
            "Phase lock loop (PLL)",
            "Power system",
            "Random harmonic",
            "Three phase three wire"
        ],
        "venue": "Gaodianya Jishu/High Voltage Engineering",
        "year": 2007,
        "id": "DDwIt3yC"
    },
    "TQ0p4FO0": {
        "authors": [
            {
                "name": "Qiu-Hua Li",
                "org": "Key Laboratory of High Voltage and Electrical New Technology"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of High Voltage and Electrical New Technology"
            },
            {
                "name": "Hua-Yong Liu",
                "org": "Power Administration Bureau of Chongqing"
            },
            {
                "name": "Feng Zhang",
                "org": "Key Laboratory of High Voltage and Electrical New Technology"
            }
        ],
        "title": "Evaluation of power quality by accelerating genetic algorithm and shepard interpolation",
        "abstract": "The synthetic quantified evaluation for power quality is one of the gist to weigh excellent or inferior of the power quality, and this is propitious to realize the electricity-purchase principle of discussing the price according to quality and high quality high price, thereby serve as to build the equitable electric power market. The problem of power quality evaluation is a desiderate problem. Also world countries have establish a series of the power quality standards, but this standards can only used to confirm the power quality is eligibility or not, can not confirm the power quality is excellent or not, therefore this standard witch only have two grades can not reflect the power quality entirely, reality and naturally. How to evaluate the power quality properly and based on this to deal with the problem of power quality reasonable and economically have been put on us imminently. This paper based on the essential of the power quality evaluation, first proposes to use the Shepard interpolation technique based on genetic algorithm for power quality evaluation, and then build the model based on the Shepard interpolation technique (SP model). This model used the random method to produce the power quality stylebook sequence based on the power quality standard. Make use of the stylebook series can confirm the power quality grade of the object through the interpolation method. The evaluation process is drove by the stylebook data, so it belongs to the non-function mode evaluation method. Using the function mode method, it should construct the relation between the evaluation indexes and the evaluation grade, the SP model presented in this paper can conquer this difficulty. Case results show that use the proposed model is objective and reasonable, with a special advantage when used in power quality evaluation, so it has value for popularizing and applying.",
        "keywords": [
            "Accelerating genetic algorithm (AGA)",
            "Comprehensive evaluation",
            "Distance resemble",
            "Electricity market",
            "Power quality",
            "Precision",
            "Shepard interpolation technique"
        ],
        "venue": "Gaodianya Jishu/High Voltage Engineering",
        "year": 2007,
        "id": "TQ0p4FO0"
    },
    "e5sYWjqn": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of High Voltage and Electrical New Technology"
            },
            {
                "name": "Qiu-Hua Li",
                "org": "Key Laboratory of High Voltage and Electrical New Technology"
            },
            {
                "name": "Hua-Yong Liu",
                "org": "Power Administration Bureau of Chongqing"
            },
            {
                "name": "Feng Zhang",
                "org": "Key Laboratory of High Voltage and Electrical New Technology"
            },
            {
                "name": "Yong-Jie Qu",
                "org": "Chongqing Electronics Polytechnic College"
            }
        ],
        "title": "Evaluation of power quality by fuzzy artificial neural network",
        "abstract": "To evaluate the power quality properly to deal with the problem of power quality reasonably and economically, the fuzzy neural network recognition which combining NN and FR was put forward for power quality evaluation, then the Fuzzy Neural Network Recognition model (FNNR) was established. This model not only calculates the power quality grade of the observation station, but also compares the differences between observation stations in the same grade. Fuzzy Neural Network Recognition simulates the thinking of the brain, and has very strong self-organizing, self-learning, self-adapting ability. The model proposed in this paper has essential differences with the actual power quality integrate-evaluating methods; the output result of the model has the characteristic of sole result and objectivity, etc. Case results show that the proposed model is objective and reasonable with a special advantage used in power quality evaluation.",
        "keywords": [
            "Comprehensive evaluation",
            "Electricity market",
            "FANN (Fuzzy Artificial Neural Network)",
            "Interpolation technique",
            "Membership degree",
            "Power quality"
        ],
        "venue": "Gaodianya Jishu/High Voltage Engineering",
        "year": 2007,
        "id": "e5sYWjqn"
    },
    "bg4OmGxO": {
        "authors": [
            {
                "name": "Qiuhua Li",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Feng Zhang",
                "org": ""
            },
            {
                "name": "Jing Meng",
                "org": ""
            },
            {
                "name": "Hongchun Wu",
                "org": ""
            }
        ],
        "title": "Design and implementation of a battery on-line monitoring system based on GPRS",
        "abstract": "The performance and quality of the battery is very important for the safe running of the power plant and transformer station. So the supervision of the battery's performance is a sticking point for the stabilization, safety and reliability of the power system. In order to supervise the running performance of the battery, this paper proposes a battery online monitoring system which is based on general packet radio service (GPRS) network. This system can supervise the voltage, current and temperature of the battery through the long-distance supervised terminal. If the battery's maintenance person wants to know the running status of the battery, he can sent a short message to the supervision cell of the system, and then the system sent the running parameter to the mobile telephone of the maintenance person or the supervision center by GPRS module through the communication network and Internet, so the real time supervision of the battery is realized. This system could also setup the alarm boundary of the voltage, current and temperature of the battery, if the battery appears abnormal, the system would sent the alarm information to the mobile telephone of the maintenance person or the supervision center, so the trouble of the battery can be fixed up immediately. In practice it shows the superiority of the system.",
        "keywords": [
            "Anti-jamming designing",
            "Battery",
            "GPRS",
            "Hardware designing",
            "Software designing"
        ],
        "venue": "Diangong Jishu Xuebao/Transactions of China Electrotechnical Society",
        "year": 2007,
        "id": "bg4OmGxO"
    },
    "zCLimgc0": {
        "authors": [
            {
                "name": "Yun-Jie Wan",
                "org": "Architectural Design and Research Institute of Guangdong Province"
            },
            {
                "name": "Lin Zhou",
                "org": "College of Electrical Engineering"
            },
            {
                "name": "Li-Wen Wang",
                "org": "Guangzhou Institute of Measuring and Testing Technology"
            },
            {
                "name": "Hai Zhang",
                "org": "Mianyang Electric Power Company"
            },
            {
                "name": "Xue Xia",
                "org": "Southwest Electric Power Design Institute"
            }
        ],
        "title": "Study on one-cycle control three-level three-phase four-leg active power filter",
        "abstract": "Multilevel active power filter (APF) that provides more than two voltage levels and less distorted waveform offers many benefits in high voltage and high power application field, so a three-level three-phase four-leg APF based on one-cycle control is presented. This scheme does not need any measured quantities of three-phase load currents, and also the complicated calculation of the harmonics and reactive current components are eliminated. By taking advantages of the pulsed and nonlinear nature of switching converters, this scheme achieves instantaneous dynamic control of the average value of a switched variable, more specifically, it takes only one switching cycle for the average value of the switched variable to reach a new steady-state after a transient. There is no steady-state error or dynamic error between the control reference and the average value of the switched variable. The controller is composed of some integrators with reset, flip-flops, comparators and linear components, having the characteristics of high precision and effectual compensation. In addition, it works under constant switching frequency modulation, thus, is desirable for industrial applications. Simulation is carried out on the basis of a mathematic model. The simulation results verify that the APF with one-cycle control can effectually compensate harmonics, improve total harmonic distortion and power factor of transmission lines.",
        "keywords": [
            "Active power filter",
            "One-cycle control",
            "Power electronics",
            "Pulse width modulation",
            "Three-level",
            "Three-phase four-leg"
        ],
        "venue": "Gaodianya Jishu/High Voltage Engineering",
        "year": 2007,
        "id": "zCLimgc0"
    },
    "hqWtUKCt": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of High Voltage Engineering and Electrical New Technology"
            },
            {
                "name": "Qiu-Hua Li",
                "org": "Key Laboratory of High Voltage Engineering and Electrical New Technology"
            },
            {
                "name": "Feng Zhang",
                "org": "Key Laboratory of High Voltage Engineering and Electrical New Technology"
            }
        ],
        "title": "New algorithm for random harmonic current detection in three phase four wire system",
        "abstract": "Active Power Filter is an important device to eliminate the pollution of harmonic, the key problem in APF is to detect the harmonic current accurately in real-time mode. Separate usage of APF needs a lot of investment early and its running efficiency is low, so APF should be used with PF, but this kind of APF needs to detect the random harmonic current. In this paper a new detection algorithm for random harmonic current in three-phase four-wire system is presented. This algorithm which is based upon the traditional i",
        "keywords": [
            "Equivalent triangle conversion",
            "Ip-iq principle",
            "Instantaneous reactive power theory",
            "Power system",
            "Random harmonic current detection",
            "Three-phase four-wire"
        ],
        "venue": "Gaodianya Jishu/High Voltage Engineering",
        "year": 2007,
        "id": "hqWtUKCt"
    },
    "2QyyzFlZ": {
        "authors": [
            {
                "name": "Peng Lei",
                "org": "Electric Power Research Institute"
            },
            {
                "name": "Lin Zhou",
                "org": "High Voltage Engineering and Electrical New Technology Key Laboratory"
            }
        ],
        "title": "One-cycle controlled three-level active power filter with the ip-iq detecting method",
        "abstract": "A shunt active power filter (APF) is a device that compensates reactive power and harmonic currents from a group of nonlinear loads. In order to not only compensate harmonic component, reactive power component, both harmonic and reactive power component, respectively, but also apply APF to higher voltage, higher power and lower distortion of output current waveform applications, a one-cycle controlled APF with neutral-point-clamped (NPC) converter and the i",
        "keywords": [
            "Active power filter",
            "Ip-iq algorithm",
            "One-cycle control",
            "Three-level",
            "Three-phase three-wire",
            "Voltage distortion"
        ],
        "venue": "Gaodianya Jishu/High Voltage Engineering",
        "year": 2007,
        "id": "2QyyzFlZ"
    },
    "9cBTVf5h": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of High Voltage Engineering and Electrical New Technology"
            },
            {
                "name": "Qiu-Hua Li",
                "org": "Key Laboratory of High Voltage Engineering and Electrical New Technology"
            },
            {
                "name": "Feng Zhang",
                "org": "Key Laboratory of High Voltage Engineering and Electrical New Technology"
            },
            {
                "name": "Xiao-Qing Tang",
                "org": "Training Centre of Sichuan Electric Power Company"
            },
            {
                "name": "Yong-Qiang Ma",
                "org": "Key Laboratory of High Voltage Engineering and Electrical New Technology"
            }
        ],
        "title": "Study and implementation of simulation system for construction technology of transmission and distribution lines",
        "abstract": "Simulator for Training System is important in the Construction of the Transmission and Distribution Lines for improving the making and efficiency of the operators and avoiding possibility of trouble. The Web-based application systems become popular in Simulator for Training System, which have the advantage of strong removability, simple interface and easy management. Web-base distributed simulation technology is the main direction in present simulation technology. The object-oriented software designing and developing technology, Browser/Server Architecture system and Java-based J2EE (Java 2 Platform Enterprise Edition) platform technology, UML (Unified Modeling Language) and traditional simulation modeling technology were researched. The Training System was designed with the Module idea which had the advantage of strong cohesion and weak coupling. The application of the system indicates that the system improves the efficiency and level of the training and promotes the lines construction greatly.",
        "keywords": [
            "Browser/server architecture",
            "J2EE",
            "Object-oriented designing and developing technology",
            "Simulation training",
            "The construction of transmission and distribution lines"
        ],
        "venue": "Xitong Fangzhen Xuebao / Journal of System Simulation",
        "year": 2008,
        "id": "9cBTVf5h"
    },
    "KM1Eldox": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Hong-Chun Wu",
                "org": ""
            },
            {
                "name": "Jing Meng",
                "org": ""
            },
            {
                "name": "Hui-Liang Xu",
                "org": ""
            },
            {
                "name": "Yong-Qiang Ma",
                "org": ""
            }
        ],
        "title": "Study of the voltage sag analysis methods",
        "abstract": "The basic concept of the voltage sag is introduced and its trait is summed up and analyzed. Also the actuality of the voltage sag is expatiated. In addition, sundry basic principles of the voltage sag and its application, characteristics and applicable range are discussed in details. Moreover, every methods are summarized and compared, and conclusion is drawn that the wavelet-transformation and S-transformation related to other analysis methods of the voltage sag could acquire preferable effect in studying the voltage sag. The analysis direction and emphasis of studying the voltage sag are put forward.",
        "keywords": [
            "Analysis methods",
            "Mathematical morphology",
            "S-transformation",
            "Short-time Fourier transformation",
            "Voltage sag",
            "Wavelet-transformation"
        ],
        "venue": "Gaodianya Jishu/High Voltage Engineering",
        "year": 2008,
        "id": "KM1Eldox"
    },
    "WrjXhbcS": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "State Key Lab. of Transmission and Distribution Equipment and Power System Safety and New Technol."
            },
            {
                "name": "Jian Wu",
                "org": "State Key Lab. of Transmission and Distribution Equipment and Power System Safety and New Technol."
            },
            {
                "name": "Qiu-Hua Li",
                "org": "State Key Lab. of Transmission and Distribution Equipment and Power System Safety and New Technol."
            },
            {
                "name": "Ke Guo",
                "org": "State Key Lab. of Transmission and Distribution Equipment and Power System Safety and New Technol."
            }
        ],
        "title": "Survey of maximum power point tracking techniques for photovoltaic array",
        "keywords": [
            "Incremental conductance",
            "Maximum power point (MPP)",
            "Maximum power point tracking (MPPT)",
            "Perturb-and-observation",
            "Photovoltaic (PV) array",
            "Photovoltaic power generation"
        ],
        "venue": "Gaodianya Jishu/High Voltage Engineering",
        "year": 2008,
        "id": "WrjXhbcS"
    },
    "YOXoZ5Zr": {
        "authors": [
            {
                "name": "Qiuhua Li",
                "org": "Chongqing University"
            },
            {
                "name": "Lin Zhou",
                "org": "Chongqing University"
            },
            {
                "name": "Qiang Liu",
                "org": "Chongqing University"
            },
            {
                "name": "Feng Zhang",
                "org": "Chongqing University"
            },
            {
                "name": "Jian Wu",
                "org": "Chongqing University"
            }
        ],
        "title": "Simulative research of MPPT for photovoltaic power system",
        "keywords": [
            "Duty cycle",
            "MPPT",
            "Perturb-and-observe method",
            "Photovoltaic power system"
        ],
        "venue": "Dianli Zidonghua Shebei / Electric Power Automation Equipment",
        "year": 2008,
        "id": "YOXoZ5Zr"
    },
    "dRJfaExA": {
        "authors": [
            {
                "name": "Qiuhua Li",
                "org": "Key Laboratory of High Voltage Engineering and Electrical New Technology"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of High Voltage Engineering and Electrical New Technology"
            },
            {
                "name": "Qiang Liu",
                "org": "Key Laboratory of High Voltage Engineering and Electrical New Technology"
            },
            {
                "name": "Huayong Liu",
                "org": "Power Administration Bureau of Chongqing"
            },
            {
                "name": "Yongjie Qu",
                "org": "Chongqing Electronics Polytechnic College"
            }
        ],
        "title": "Rural power line theftproof system based on GPRS",
        "keywords": [
            "Anti-jamming design",
            "GPRS",
            "Power line theftproof system"
        ],
        "venue": "Dianli Zidonghua Shebei / Electric Power Automation Equipment",
        "year": 2008,
        "id": "dRJfaExA"
    },
    "dOt0U2j5": {
        "authors": [
            {
                "name": "Ming Xu",
                "org": "The 712 Research Institute"
            },
            {
                "name": "Jian Peng",
                "org": "The 712 Research Institute"
            },
            {
                "name": "Lin Zhou",
                "org": "College of Electric Engineering"
            }
        ],
        "title": "Relationship between following performance and circuit parameters of APF controlled by triangle-wave pulse width modulated current",
        "abstract": "TPWMC (Triangle-wave Pulse Width Modulated Current) control is widely used in APF (Active Power Filter), which has simple circuit and fixed switching frequency, but great following error. By analyzing the following performance of TPWMC control, it is found that the great error is induced by the difference between the rising time and falling time of compensating current in a cycle and it can be lowered by time control. The relationship between triangle-wave parameter and APF is set according to the control conditions. The system with single-phase shunt APF controlled by TPWMC is simulated to verify the correctness of the set relationship. Simulation results show that, the following speed of TPWMC-controlled APF can be improved and its error reduced by properly setting its parameters according to the relationship.",
        "keywords": [
            "Active power filter",
            "Following performance",
            "Triangle-wave pulse width modulation"
        ],
        "venue": "Dianli Zidonghua Shebei / Electric Power Automation Equipment",
        "year": 2008,
        "id": "dOt0U2j5"
    },
    "Xle1VJkS": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "The Key Laboratory of High Voltage Engineering and Electrical New Technology"
            },
            {
                "name": "Jing Meng",
                "org": "Sichuan Xixing Electric Power Technology Consulting Co. Ltd"
            },
            {
                "name": "Qiang Liu",
                "org": "The Key Laboratory of High Voltage Engineering and Electrical New Technology"
            },
            {
                "name": "Hui-Liang Xu",
                "org": "The Key Laboratory of High Voltage Engineering and Electrical New Technology"
            },
            {
                "name": "Hong-Chun Wu",
                "org": "The Key Laboratory of High Voltage Engineering and Electrical New Technology"
            }
        ],
        "title": "Detecting methods of harmonics and reactive current based on instantaneous reactive power theory",
        "keywords": [
            "Circuit structure",
            "Harmonics detection",
            "Instantaneous reactive power theory",
            "LPF",
            "PLL",
            "Reactive current",
            "Vector commutation"
        ],
        "venue": "Gaodianya Jishu/High Voltage Engineering",
        "year": 2009,
        "id": "Xle1VJkS"
    },
    "rYfWyTHd": {
        "authors": [
            {
                "name": "Zongwei Lu",
                "org": "School of Electrical Engineering"
            },
            {
                "name": "ZhiDe Tang",
                "org": "School of Electrical Engineering"
            },
            {
                "name": "ZhiHong Fu",
                "org": "School of Electrical Engineering"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Electrical Engineering"
            }
        ],
        "title": "Accurate analysis of RLC trees by laguerre polynomials",
        "abstract": "In this paper, we propose one efficient algorithm for the transient analysis of RLC trees. Based on MNA equations, we derive the recursive formulas for the coefficients of Laguerre polynomials. Via Arnoldi algorithm, we can reduce the order of matrix directly in the time-domain instead of frequency-domain, which is often more time-consuming because inverse Laplace transformation or inverse fast Fourier transformation is needed. Furthermore, the passivity of the network reduced by our method is guaranteed because of the congruence transformations. It is shown through one example on the transient analysis of one RLC tree that the average error by our method is within 10% in comparison with results by HSPICE and our method can run faster than HSPICE. \u00a9 2009 IEEE.",
        "keywords": [
            "Circuit simulation",
            "Interconnect tree",
            "Krylov subspace",
            "Laguerre polynomials",
            "Model reduction",
            "RLC"
        ],
        "venue": "2009 International Conference on Signal Processing Systems, ICSPS 2009",
        "year": 2009,
        "id": "rYfWyTHd"
    },
    "a4jLRC1V": {
        "authors": [
            {
                "name": "Ke Deng",
                "org": ""
            },
            {
                "name": "Dai-Chun Qin",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            }
        ],
        "title": "An on-line monitoring system of electric power transformers based on three detecting technologies",
        "abstract": "Recent years, electric wire and transformer of the rural power lines have been stolen occasionally, which disturbs power supply orders and causes severe loss to the state. On-line monitor system of electric transformer based on three detector technology is developed to fight against the theft phenomenon. This paper describes the system construction, technical features and application effect in brief. This system consists of monitoring unit, supervision center and the patrolling personnel. The three detector technology and wireless picture transmission technology are firstly used against theft in power system. A series of experiments prove its applicability. When there is someone approaching to steal the transformer, the monitoring unit about 2 meters hight above can make a alarm speech. At the same time, it takes the pictures in site. Then it sends messages and pictures to the supervision center through GPRS. If the electric wire is broken, the monitoring unit sends information of the broken line to the supervision center so that the center could inform the patrol person to catch up with the scene in time. With this system the transformer and wire can be protected in maximum safety.",
        "keywords": [
            "Guard against theft",
            "On-line monitoring",
            "Three detector technology",
            "Wireless picture transmission technology"
        ],
        "venue": "Dianli Xitong Baohu yu Kongzhi/Power System Protection and Control",
        "year": 2010,
        "id": "a4jLRC1V"
    },
    "Vnk0xjMW": {
        "authors": [
            {
                "name": "Yong-Qiang Ma",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Jian Wu",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Qun-Hui Fang",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Qing-Hua Zeng",
                "org": "Yongchuan Power Supply Bureau"
            },
            {
                "name": "You-Yu Zhang",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            }
        ],
        "title": "A new approach to measure voltage flicker caused by interharmonics",
        "keywords": [
            "Interharmonic",
            "Interpolation",
            "Power quality",
            "Secondary sampling",
            "Voltage flicker"
        ],
        "venue": "Dianwang Jishu/Power System Technology",
        "year": 2010,
        "id": "Vnk0xjMW"
    },
    "09fIyq7U": {
        "authors": [
            {
                "name": "You-Yu Zhang",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Ke Guo",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Qiang Liu",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Chuan-Tao Si",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Jian Wu",
                "org": "Extra-High Voltage Bureau"
            }
        ],
        "title": "A method to compute voltage unbalance factor in three-phase three-wire system",
        "keywords": [
            "Negativesequence component",
            "Positive-sequence component",
            "Power quality",
            "Three-phase three-wire system",
            "Three-phase voltage unbalance"
        ],
        "venue": "Dianwang Jishu/Power System Technology",
        "year": 2010,
        "id": "09fIyq7U"
    },
    "bcw08nKz": {
        "authors": [
            {
                "name": "Dai-Chun Qin",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Ke Guo",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Qiang Liu",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Kun Fang",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            }
        ],
        "title": "A new method of power quality de-noising based on the wavelet neural network",
        "keywords": [
            "De-noising",
            "Level of wavelet transformation",
            "Power quality",
            "Threshold value",
            "Wavelet neural network"
        ],
        "venue": "Dianli Xitong Baohu yu Kongzhi/Power System Protection and Control",
        "year": 2010,
        "id": "bcw08nKz"
    },
    "NoA1Erho": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Youyu Zhang",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Qiang Liu",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Ke Guo",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Lu Dai",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Yi Zeng",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            }
        ],
        "title": "A flicker measuring method based on improved sine interpolation",
        "keywords": [
            "Flicker measuring",
            "Flickermeter",
            "IEC",
            "Interhamonic",
            "Sine interpolation"
        ],
        "venue": "Dianli Xitong Zidonghua/Automation of Electric Power Systems",
        "year": 2010,
        "id": "NoA1Erho"
    },
    "h0vQEOdX": {
        "authors": [
            {
                "name": "Kun Fang",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Qiang Liu",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Ke Guo",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Daichun Qin",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Youyu Zhang",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Chuantao Si",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            }
        ],
        "title": "A survey on double-frequency conversion theory for converters",
        "keywords": [
            "Double-frequency conversion theory",
            "Loss reduction from current shunting",
            "Operating mood control",
            "Parameter design"
        ],
        "venue": "Dianwang Jishu/Power System Technology",
        "year": 2010,
        "id": "h0vQEOdX"
    },
    "Ew1rsjE4": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Fang-Cheng Jia",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Ke Guo",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Yu Feng",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            }
        ],
        "title": "Testing analysis on a kind of PV generation simulation system using RT-LAB",
        "abstract": "The maximum power point tracking (MPPT) controller in the Photovoltaic system is the key mean to verify all kinds of MPPT control algorithms. But the development of actual controller has the defects of needing long periods, artificial code writing and so on. RT-LAB real-time simulation platform is an advanced model-based engineering design and test application platform. The outstanding real-time performance in the current experimental study and engineering design made it used more and more widely. Therefore, it is necessary to introduce its hardware and software structure and real-time performance in detail. This paper gare a comprehensive and systematic introduction to hardware architecture, software architecture and simulation process of RT-LAB. It also presented a semi-physical simulation experiment of photovoltaic system MPPT using the features of Photovoltaic MPPT and semi-physical Real-Time simulation technology. The MPPT control strategy is achieved by establishing model using simulink package. Other parts of the main circuit were physical circuit except controller. The parameter adjustment functions on line of RT-LAB can easily optimize controller parameters. Two special tools ARTEMIS and RT-Events used in power electronics were described in detail. The RT-LAB software modeling standard was also illustrated. The testing results showed that the usage of RT-LAB for the development of photovoltaic controller can resolve many problems in the current controller development. The application of RT-LAB in photovoltaic systems provides a reference for the microgrid, smartgrid and other real-time systems.",
        "keywords": [
            "Distributed real-time simulation",
            "Modeling",
            "Photovoltaic generation",
            "Power electronics",
            "RT-LAB",
            "The maximum power point tracking(MPPT)"
        ],
        "venue": "Gaodianya Jishu/High Voltage Engineering",
        "year": 2010,
        "id": "Ew1rsjE4"
    },
    "dEZpJRJq": {
        "authors": [
            {
                "name": "Saisai Niu",
                "org": "College of Mechanical and Electrical Engineering"
            },
            {
                "name": "Jianxin Shen",
                "org": "College of Mechanical and Electrical Engineering"
            },
            {
                "name": "Chun Liang",
                "org": "College of Mechanical and Electrical Engineering"
            },
            {
                "name": "Lin Zhou",
                "org": "College of Mechanical and Electrical Engineering"
            },
            {
                "name": "Bangming Li",
                "org": "College of Mechanical and Electrical Engineering"
            }
        ],
        "title": "Research on human retinal cell image restoration",
        "abstract": "In order to improve the observation effect and further study on the human retinal cell image, image processing technology is used for restoration from the distortion and degradation of images, which are acquired through retinal cell imaging system based on adaptive optics. In this paper, two commonly used image restoration algorithms were introduced: Wiener filter and Lucy-Richardson. On this basis, a semi-blind deconvolution image restoration algorithm based on Sobel operator is proposed. The edges detected by Sobel operator were processed differently from other region, which could both effectively remove the noise, and maintain the image detail well. Finally, frequency domain function and point sharpness function are introduced to evaluate the images which are restored with the above algorithms, the results show that the Sobel based semi-blind deconvolution algorithm can achieve quite better results in restoration of cell image. \u00a92010 IEEE.",
        "keywords": [
            "Blind deconvolution",
            "Edge detection",
            "Image restoration",
            "Retinal cell",
            "Wiener filter"
        ],
        "venue": "Proceedings - 2010 3rd International Congress on Image and Signal Processing, CISP 2010",
        "year": 2010,
        "id": "dEZpJRJq"
    },
    "KLK4FtLH": {
        "authors": [
            {
                "name": "Yuliang Wang",
                "org": "College of Mechanical and Electrical Engineering"
            },
            {
                "name": "Jianxin Shen",
                "org": "College of Mechanical and Electrical Engineering"
            },
            {
                "name": "Wenhe Liao",
                "org": "College of Mechanical and Electrical Engineering"
            },
            {
                "name": "Lin Zhou",
                "org": "College of Mechanical and Electrical Engineering"
            }
        ],
        "title": "Automatic fundus images mosaic based on SIFT feature",
        "abstract": "An automatic fundus image mosaic algorithm based on SIFT feature is presented, to overcome the characteristics of low contrast and the geometric distortion between different field of view of the fundus images. The SIFT feature of fundus images are extracted and described using vectors to determine the matching feature point pairs between two images, outlier point pairs are rejected using MLESAC algorithm employed RST model, the transformation matrix is then computed according to purified matching point pairs between images, at last image registration and image mosaic is implemented. The mosaic results of multiple images obtained by fundus camera show that the algorithm has good robustness and stability, and high-precision automatic fundus image mosaic can be achieved. \u00a92010 IEEE.",
        "keywords": [
            "Fundus images",
            "Image fusion",
            "Image registration",
            "Images mosaic",
            "SIFT"
        ],
        "venue": "Proceedings - 2010 3rd International Congress on Image and Signal Processing, CISP 2010",
        "year": 2010,
        "id": "KLK4FtLH"
    },
    "8Ob02g8t": {
        "authors": [
            {
                "name": "Ke Guo",
                "org": "State Key Laboratory of Transmission and Distribution Equipment"
            },
            {
                "name": "Yan Chen",
                "org": "State Key Laboratory of Transmission and Distribution Equipment"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Transmission and Distribution Equipment"
            },
            {
                "name": "Lu Dai",
                "org": "State Key Laboratory of Transmission and Distribution Equipment"
            }
        ],
        "title": "Nonlinear behavior in current mode research of Z-source DC/DC converter",
        "abstract": "Z-source converter as a kind of power converter will be responsible for the energy transmission, the paper focuses on the nonlinear characteristic analysis of Z-source DC/DC converter, in the continuous conduction mode (CCM), take Z-source converter with peak current control as the research object, establish stroboscopic mapping model for analyzing its nonlinear characteristic. the experiment result proves that Z-source converter stroboscopic mapping model is correct for analyzing its nonlinear behavior, which provides a theoretical basis for optimal design and control. \u00a9 (2011) Trans Tech Publications.",
        "keywords": [
            "Bifurcation",
            "Chaos",
            "Nonlinear",
            "Stroboscopic mapping model",
            "Z-source converter"
        ],
        "venue": "Applied Mechanics and Materials",
        "year": 2011,
        "id": "8Ob02g8t"
    },
    "ViBkucfh": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Yong Huang",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Ke Guo",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Yu Feng",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            }
        ],
        "title": "A survey of energy storage technology for micro grid",
        "abstract": "This paper introduces the academic research of storage technology applied to micro grid. Firstly, it reviews the development of storage technology, expounds the research meanings and values, and analyzes the role of the energy storage in micro grid. Then the application research of the battery storage, flywheel storage, superconductive magnetic energy storage, supercapacitor storage, hybrid storage and other energy storage in micro grid are discussed. The advantages and disadvantages of various storage methods are introduced, and their performance indexes are compared. Finally, considering the characteristics and requirements of micro grid, both some existing problems and the future development trend of energy storage technology are presented.",
        "keywords": [
            "Battery storage",
            "Energy storage technology",
            "Flywheel storage",
            "Hybrid storage",
            "Micro grid",
            "Supercapacitor storage",
            "Superconductive magnetic energy storage (SMES)"
        ],
        "venue": "Dianli Xitong Baohu yu Kongzhi/Power System Protection and Control",
        "year": 2011,
        "id": "ViBkucfh"
    },
    "ON4FX2d0": {
        "authors": [
            {
                "name": "Yan Chen",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Qiang Liu",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Jian Wu",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            }
        ],
        "title": "MPPT pattern search tracking control of photovoltaic system based on genetic encoding",
        "keywords": [
            "Genetic encoding",
            "MPPT",
            "Optimization algorithm",
            "Pattern search",
            "Photovoltaic system",
            "Tracking control"
        ],
        "venue": "Shenyang Gongye Daxue Xuebao/Journal of Shenyang University of Technology",
        "year": 2011,
        "id": "ON4FX2d0"
    },
    "xo4IPArj": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "State Key Lab. of Transmission and Distribution Equipment and Power System Safety and New Technology"
            },
            {
                "name": "Yan Chen",
                "org": "State Key Lab. of Transmission and Distribution Equipment and Power System Safety and New Technology"
            },
            {
                "name": "Ke Guo",
                "org": "State Key Lab. of Transmission and Distribution Equipment and Power System Safety and New Technology"
            },
            {
                "name": "Fangcheng Jia",
                "org": "State Key Lab. of Transmission and Distribution Equipment and Power System Safety and New Technology"
            }
        ],
        "title": "New approach for MPPT control of photovoltaic system with mutative-scale dual-carrier chaotic search",
        "abstract": "As the output power of photovoltaic (PV) array changes with the change of external environment and load, the maximum power point tracking (MPPT) technology is needed to bring the efficiency of PV device into full play. In this paper, the chaos search theory is first applied on the MPPT technology of PV system; the chaos search algorithm based on dual carrier increases the adequacy of chaos search and overcomes the blindness of traditional chaos search, thus improves the search efficiency and solves the problem of multiple MPP under partially shadowing conditions. Comparative tests show that the proposed method can track the step response quickly and accurately; at the same time get better optimization result. Simulation and experimental results showed the effectiveness and good performance of the proposed method. \u00a9 2011 IEEE.",
        "keywords": [
            "Chaos search",
            "dual carrier",
            "maximum power point tracking (MPPT)",
            "multiple MPP",
            "photovoltaic (PV) array"
        ],
        "venue": "IEEE Transactions on Power Electronics",
        "year": 2011,
        "id": "xo4IPArj"
    },
    "7wmF9mpi": {
        "authors": [
            {
                "name": "Zong-Wei L\u00fc",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Zhi-De Tang",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Qian Zhang",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Li-Sen Lin",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            }
        ],
        "title": "One efficient and fast method for the removal of high-density salt and pepper noise",
        "abstract": "One simple and efficient method for the removal of high-density salt and pepper noise is proposed in this paper. In the proposed method, we calculate the mean value of the non salt and pepper pixels in the window centered at the current salt and pepper pixel. Then, we update the salt and pepper pixel with the mean value at the different phases. Although the principle in the proposed method is quite simple, the experimental results show that the proposed method behaves excellently for all noise ratios, from 10% to 90%. The proposed method can preserve the details of the original image well. Furthermore, the run time for the proposed method is quite short, which makes it possible for the real applications.",
        "keywords": [
            "Details-preserving",
            "Image process",
            "Impulse noise",
            "Median filter"
        ],
        "venue": "Tien Tzu Hsueh Pao/Acta Electronica Sinica",
        "year": 2011,
        "id": "7wmF9mpi"
    },
    "suTbH54T": {
        "authors": [
            {
                "name": "Zongwei Lu",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security"
            },
            {
                "name": "Zhide Tang",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security"
            },
            {
                "name": "Hao Yang",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security"
            }
        ],
        "title": "Brightness preserving histogram equalization based on cumulative distribution function",
        "abstract": "To preserve brightness better, one efficient method for contrast enhancement is proposed based on histogram equalization. First, the cumulative distribution function is used to calculate critical points which play an important role in preserving brightness. Then, the histogram is separated into several sub-histograms by critical points and equalization is applied for each sub-histogram. Finally, the enhanced images are obtained by merging the sub-images for each sub-histogram. The experimental results show that the proposed method can preserve the brightness better and enhance the contrast more efficiently than most other histogram equalization based methods.",
        "keywords": [
            "Brightness preservation",
            "Contrast enhancement",
            "Histogram equalization"
        ],
        "venue": "Jisuanji Fuzhu Sheji Yu Tuxingxue Xuebao/Journal of Computer-Aided Design and Computer Graphics",
        "year": 2011,
        "id": "suTbH54T"
    },
    "hed2XqvH": {
        "authors": [
            {
                "name": "Wang Fu",
                "org": "State key Laboratory of Power Transmission Equipment and System Security"
            },
            {
                "name": "Lin Zhou",
                "org": "State key Laboratory of Power Transmission Equipment and System Security"
            },
            {
                "name": "Ke Guo",
                "org": "State key Laboratory of Power Transmission Equipment and System Security"
            },
            {
                "name": "Qiang Liu",
                "org": "State key Laboratory of Power Transmission Equipment and System Security"
            },
            {
                "name": "Lu Dai",
                "org": "State key Laboratory of Power Transmission Equipment and System Security"
            },
            {
                "name": "Yong Huang",
                "org": "State key Laboratory of Power Transmission Equipment and System Security"
            }
        ],
        "title": "Research on engineering analytical model of solar cells",
        "keywords": [
            "Gravity acceleration",
            "Horizontal projectile motion",
            "Maximum power point",
            "Solar cell model"
        ],
        "venue": "Diangong Jishu Xuebao/Transactions of China Electrotechnical Society",
        "year": 2011,
        "id": "hed2XqvH"
    },
    "BtG8R1Dh": {
        "authors": [
            {
                "name": "Yan Chen",
                "org": "State Key Lab. of Transmission and Distribution Equipment and Power System Safety and New Technol."
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Lab. of Transmission and Distribution Equipment and Power System Safety and New Technol."
            },
            {
                "name": "Jian Lei",
                "org": "State Key Lab. of Transmission and Distribution Equipment and Power System Safety and New Technol."
            },
            {
                "name": "Yuanxing Gan",
                "org": "Beibei District Supply Bureau of Chongqing Electric Power Corp."
            }
        ],
        "title": "Research on the Z-source inverter grid-connected control of micro-grid system based on differential geometry",
        "abstract": "For the Z-source inverter used in the distributed generation system and its grid-connected control, the paper takes the photovoltaic system as the example. According to the nonlinear characteristic of Z-source inverter, the affine model of Z-source inverter DC-link and AC side are created. Based on the differential geometry, the proper coordinate transformation and pre-feedback are constructed, and the original nonlinear system is exact linearized, then designed linear optimal controller for the system. The inverter integrates three functions including maximum power point tracking (MPPT), step-up/down DC-side voltage and output grid-connected. The simulation and experiment are performed to validate the strategies: when input condition of the photovoltaic array changes, this method has better performance than PI control.",
        "keywords": [
            "Differential geometry",
            "Grid-connected",
            "Micro-grid",
            "Photovoltaic",
            "Z-source inverter"
        ],
        "venue": "Diangong Jishu Xuebao/Transactions of China Electrotechnical Society",
        "year": 2012,
        "id": "BtG8R1Dh"
    },
    "LBjHTsHZ": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "State Key Lab. of Transmission and Distribution Equipment and Power System Safety and New Technology"
            },
            {
                "name": "Bing Yang",
                "org": "State Key Lab. of Transmission and Distribution Equipment and Power System Safety and New Technology"
            },
            {
                "name": "Ke Guo",
                "org": "State Key Lab. of Transmission and Distribution Equipment and Power System Safety and New Technology"
            },
            {
                "name": "Hong-Xin Li",
                "org": "State Key Lab. of Transmission and Distribution Equipment and Power System Safety and New Technology"
            },
            {
                "name": "Zheng-Mao Zhang",
                "org": "State Key Lab. of Transmission and Distribution Equipment and Power System Safety and New Technology"
            }
        ],
        "title": "The progress and development trend of the DC injection issue in PV grid-connected systems",
        "abstract": "Limitation of direct current (DC) injection into the network is an important requirement for grid-connected photovoltaic (PV) systems. The DC component in the grid-connected current of PV systems is specified by domestic and international standards. With the promotion of the non-isolated PV grid systems, the DC injection problem has been increasingly concerned. According to related articles, the causes and the adverse effects of DC injection are introduced. The proposed solutions are classified into three categories by the theory of solving the DC injection problem: the DC current suppressed inverters, detection and compensation method and capacitor blocking method. The principle of each method is presented, and their advantages and disadvantages are stated. The characteristics of various methods are further summarized by comparisons. Finally, the prospect of the resolvent for DC injection in PV grid-connected systems is also made.",
        "keywords": [
            "Capacitor blocking method",
            "DC current suppressed inverters",
            "DC injection",
            "Detection and compensation method",
            "Non-isolated PV grid-connected systems",
            "Photovoltaic (PV)"
        ],
        "venue": "Dianli Xitong Baohu yu Kongzhi/Power System Protection and Control",
        "year": 2012,
        "id": "LBjHTsHZ"
    },
    "CNVWnqoL": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Yu Feng",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Ke Guo",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Qiang Liu",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Fangcheng Jia",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Yong Huang",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            }
        ],
        "title": "Research on modeling and control strategy for single-phase photovoltaic grid-connected inverter",
        "keywords": [
            "Compound control",
            "LCL filter",
            "Modeling",
            "PR control",
            "PV grid-connected inverter",
            "Reactive damping"
        ],
        "venue": "Taiyangneng Xuebao/Acta Energiae Solaris Sinica",
        "year": 2012,
        "id": "CNVWnqoL"
    },
    "6wAe3gPu": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Yan Chen",
                "org": ""
            },
            {
                "name": "Qiang Liu",
                "org": ""
            },
            {
                "name": "Jian Wu",
                "org": ""
            }
        ],
        "title": "Maximum power point tracking (MPPT) control of a photovoltaic system based on dual carrier chaotic search",
        "keywords": [
            "Chaos search",
            "Dual carrier",
            "MPPT",
            "Photovoltaic array"
        ],
        "venue": "Journal of Control Theory and Applications",
        "year": 2012,
        "id": "6wAe3gPu"
    },
    "2ihjRcGC": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Yi Zeng",
                "org": ""
            },
            {
                "name": "Ke Guo",
                "org": ""
            },
            {
                "name": "You-Yu Zhang",
                "org": ""
            },
            {
                "name": "Hong-Xin Li",
                "org": ""
            },
            {
                "name": "Jian Lei",
                "org": ""
            }
        ],
        "title": "Development of photovoltaic grid-connected system with power quality regulatory function",
        "abstract": "Nowadays power systems have higher demand on power quality, and the photovoltaic (PV) grid-connected system usually operates in low utilization due to the characteristics of intermittency and uncertainty, therefore, improving the utilization rate of PV grid-connected system and power quality of grid power system attracts wide attention. This paper outlines the development background and significance of power quality regulatory function in the PV grid-connected system, and summarizes the effect of PV grid-connected system on grid power quality. It concludes the methods to suppress harmonics and improve voltage profile according to different control methods and structures. The characteristics and application ranges of different methods are analyzed with examples and simulations. Then the main aspects, such as weather circumstances, load condition, real capacity, regulatory objects, system types, economic cost, etc. are proposed. Finally, the existing problems of the PV grid-connected system with power quality regulatory function are pointed out and its study direction in the future is also looked ahead.",
        "keywords": [
            "Harmonics",
            "Photovoltaic grid-connected system",
            "Power quality",
            "Unified power quality conditioner",
            "Voltage dip"
        ],
        "venue": "Dianli Xitong Baohu yu Kongzhi/Power System Protection and Control",
        "year": 2012,
        "id": "2ihjRcGC"
    },
    "NfVFY89B": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Linqiang Zhang",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Bo Liao",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Yanping Long",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Huaihua Li",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Jinqi Du",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            }
        ],
        "title": "Research on control strategy of single-phase photovoltaic inverter",
        "abstract": "To remedy the defect that quasi-proportional-resonant (PR) controller could not provide phase angle compensation, the principle of quasi-PR control was analyzed, and based on PR control method an improved quasi-proportional-resonant differential (PRD) control method was proposed, thus under the condition that without changing the control characteristic of original quasi-PR controller abovementioned defect could be remedied. Results of analysis and comparison showed that in both aspects of stability and steady state error the response effect of quasi-PRD control was better than response effects of traditional PID control and quasi-PR control. The parameter design process of PRD control method was derived. Results of simulation and experiments showed that PRD control method could effectively shorten the period of dynamic response, therefore the effectiveness and feasibility of the proposed PRD control method were verified.",
        "keywords": [
            "Photovoltaic inverter",
            "PID control",
            "Quasi-PR control",
            "Quasi-PRD control"
        ],
        "venue": "Dianwang Jishu/Power System Technology",
        "year": 2012,
        "id": "NfVFY89B"
    },
    "8jYYigLM": {
        "authors": [
            {
                "name": "Ming Yang",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Zhi-Guo Zhang",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            }
        ],
        "title": "Grid synchronous strategy for three-phase grid-connected power converters under grid faulty conditions",
        "abstract": "For the shortcoming of the traditional synchronous reference frame phase-locked loop(SRF-PLL) under unbalanced and distorted grid conditions, a new grid synchronous strategy was presented, which is an extension of the traditional SRF-PLL. This is achieved by combining the proposed positive-sequence voltage detector and the traditional SRF-PLL. The resultant grid synchronous strategy is able to quickly and accurately detect the amplitude, phase and other information of the positive-sequence voltage component even under unbalanced and distorted grid conditions. A detailed description and derivation of the new grid synchronous strategy were presented. Moreover, the behavior of the new grid synchronous strategy with highly unbalanced and distorted grid has been validated by means of simulation and experimental results, demonstrating its excellent performance.",
        "keywords": [
            "Grid faulty",
            "Grid synchronous",
            "Positive-sequence component",
            "Power converters",
            "Synchronous reference frame phase-locked loop"
        ],
        "venue": "Dianji yu Kongzhi Xuebao/Electric Machines and Control",
        "year": 2012,
        "id": "8jYYigLM"
    },
    "BYcGzpBu": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Taoying Li",
                "org": ""
            },
            {
                "name": "Yan Chen",
                "org": ""
            },
            {
                "name": "Yingying Yu",
                "org": ""
            }
        ],
        "title": "The semi-join query optimization in distributed database system",
        "abstract": "In distributed database system, the distributed deposition and redundancy data brought convenient to fault recovery, but they make distributed query processing more complicated at the same time. Query optimization and processing is one of the key technologies in distributed database system. It generally uses semi-join operation to improve the time response performance of query and reduce communication cost. This paper briefly described the corresponding concepts and characteristics of distributed database system, summarized the goals of distributed database query optimization, and analyzed the query optimization process based on semi-join operation combined with the practical application. In addition, it introduced a classical algorithm which is used for multiple connection and query optimization based on the semi-join query optimization, the SDD-1 algorithm. \u00a9 2012. The authors - Published by Atlantis Press.",
        "keywords": [
            "Distributed database",
            "Query optimization",
            "Semi-join operation"
        ],
        "venue": "Proceedings of the 2012 National Conference on Information Technology and Computer Science, CITCS 2012",
        "year": 2012,
        "id": "BYcGzpBu"
    },
    "SJrq2LJW": {
        "authors": [
            {
                "name": "Ke Guo",
                "org": "State Key Lab. of Transmission and Distribution Equipment and Power System Safety and New Technol."
            },
            {
                "name": "Hong-Xin Li",
                "org": "State Key Lab. of Transmission and Distribution Equipment and Power System Safety and New Technol."
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Lab. of Transmission and Distribution Equipment and Power System Safety and New Technol."
            },
            {
                "name": "Bing Yang",
                "org": "State Key Lab. of Transmission and Distribution Equipment and Power System Safety and New Technol."
            },
            {
                "name": "Yi Zeng",
                "org": "State Key Lab. of Transmission and Distribution Equipment and Power System Safety and New Technol."
            },
            {
                "name": "Jian Lei",
                "org": "State Key Lab. of Transmission and Distribution Equipment and Power System Safety and New Technol."
            }
        ],
        "title": "Implementation of single-phase Z-source inverter grid-connected system based on inductor current control",
        "abstract": "Capacitor voltage control of Z source inverter has an RHP zero, which results in the negative regulation of system step responses and makes the corresponding controller design complicated. In view of this problem, we propose a new control strategy by controlling the inductor current to steady the output of Z source inverter. Taking single-phase Z source inverter grid-connected system as an example, we establish a small signal model using state-space average method, analyze the transfer function from control to the inductor current and know that it does not contain RHP zero, thus the current controller design is simple. Then we detail the design of Z source inductor current controllers and grid-connected current controllers. Finally the validity of the controller is proved by the Matlab/simulink and RT-LAB experimental results. It shows a certain practical value.",
        "keywords": [
            "Gird-connected",
            "Inductor current control",
            "Modeling",
            "RHP zero",
            "Z source inverter"
        ],
        "venue": "Dianli Xitong Baohu yu Kongzhi/Power System Protection and Control",
        "year": 2012,
        "id": "SJrq2LJW"
    },
    "fhy5jlVQ": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Department of Electrical Engineering, Chongqing University"
            },
            {
                "name": "Yang Chao",
                "org": "Department of Electrical Engineering, Chongqing University"
            }
        ],
        "title": "The research of reactive power control strategy for grid-connected photovoltaic plants",
        "abstract": "Grid-connected photovoltaic (PV) plants should have independent control of reactive power to provide reactive power support to the grid. The study analyzes the impact the varying output of the active and reactive power of photovoltaic plants have on network voltage, and derives the relationship between active and reactive power change and voltage change amount. A reactive power control strategy of for grid-connected PV plants is proposed. It shows that voltage fluctuation at point of common coupling (PCC) caused by PV plants will be suppressed. The overall control strategy scheme diagram of active power and reactive power of PV plants is structured in stationary frame, avoiding the complex aspects of the phase-locked loop (PLL) and decoupling. The control method is analyzed under the adverse grid conditions, the adverse impact on the grid current caused by the outlets voltage distortion and imbalance is suppressed. The constraint condition of the reactive power of the inverter is analyzed and deduced. Simulation results prove the validity of the theoretical analysis, demonstrating its excellent performance. \u00a9 2013 Infonomics Society.",
        "keywords": [
            "grid-connected PV plant",
            "independent control of reactive power",
            "reactive power constraint",
            "stationary reference frame",
            "voltage fluctuation"
        ],
        "venue": "2013 World Congress on Sustainable Technologies, WCST 2013",
        "year": 2013,
        "id": "fhy5jlVQ"
    },
    "UmkJHg1T": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Bo Liao",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Yanping Long",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Linqiang Zhang",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Huaihua Li",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Jinqi Du",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            }
        ],
        "title": "Grid-connected photovoltaic power conditioner system based on amplitude integral",
        "abstract": "The accurate detection of harmonics and reactive currents and the generation of photovoltaic active current reference are essential for the control of three-phase grid-connected photovoltaic power conditioner system. In order to get the photovoltaic active current with same frequency and phase as the positive-sequence fundamental voltage of grid, the influence of parameter K in the amplitude integral positive-sequence fundamental extraction on the phase deviation of output positive-sequence fundamental voltage is analyzed and the relationship between K and frequency/phase deviation of positive-sequence fundamental voltage is derived. The positive-sequence fundamental voltage can be accurately extracted when K is set properly. Synchronous sine or cosine signals can be obtained without PLL. Based on i",
        "keywords": [
            "Amplitude integral",
            "Photovoltaic power conditioner system",
            "Power quality",
            "Reference current calculation",
            "Selector",
            "Solar energy"
        ],
        "venue": "Dianli Zidonghua Shebei/Electric Power Automation Equipment",
        "year": 2013,
        "id": "UmkJHg1T"
    },
    "4BfomSVG": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Huai-Hua Li",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Lin-Qiang Zhang",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Bo Liao",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Yan-Ping Long",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Jin-Qi Du",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            }
        ],
        "title": "Small-signal dynamic modeling of grid-connected PV system and eigenvalue sensitivity analysis of the controller parameters",
        "abstract": "The ideal inverter models are currently used to analyze the small-signal stability of the grid-connected PV system, which did not consider the impact of the control parameter. To analyze the dynamics of the photovoltaic grid-connected system, a complete small-signal model of two-stage three-phase grid-connected PV system is developed. This integrated model consists of two sub-models: one is the model of main circuit, the other is the model of double closed-loop control system of MPPT and voltage and current. Based on the above model, the parameters of the control system on the grid system eigenvalue sensitivity are calculated, and the impact of each controller parameters on the system small signal stability is analyzed. The analysis result shows that the small signal stability of the system can be improved by adjusting the controller parameters, and provides a theoretical basis for optimization design of the controller.",
        "keywords": [
            "Controller parameters",
            "Eigenvalue sensitivity",
            "Photovoltaic grid-connected system",
            "Small-signal dynamic model",
            "Small-signal stability"
        ],
        "venue": "Dianli Xitong Baohu yu Kongzhi/Power System Protection and Control",
        "year": 2013,
        "id": "4BfomSVG"
    },
    "tq9oRr0U": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Yan-Ping Long",
                "org": "Yinzhou Power Supply Bureau"
            },
            {
                "name": "Jiang-Ning Xie",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            }
        ],
        "title": "Controlling chaos in H-bridge converter with Washout filter",
        "abstract": "In order to control the complex behaviors occurring at the H-bridge converters, the chaos controlling technology of Washout filter is introduced into the H-bridge converters, which controls the chaos appearing in the H-bridge DC chopper and AC inverter respectively. The chaos control effect, when the system parameters are, or are not disturbed, is also analyzed. In accordance with the discrete model of the system with chaos control, Jacobian matrix is gained, and the restrictions of the control coefficients brought by Washout filter are deduced. The numerical simulation results show that the chaos which exists in the two working modes of H-bridge converter can be controlled effectively by this method, even can exhibit certain robustness and disturbance-rejection ability when the system parameters are perturbed.",
        "keywords": [
            "Chaos control",
            "Discrete model",
            "H-bridge converter",
            "Numerical simulation",
            "Washout filter"
        ],
        "venue": "Dianli Xitong Baohu yu Kongzhi/Power System Protection and Control",
        "year": 2013,
        "id": "tq9oRr0U"
    },
    "5e7izINu": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Ming Yang",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Qiang Liu",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Ke Guo",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            }
        ],
        "title": "New control strategy for three-phase grid-connected LCL inverters without a phase-locked loop",
        "keywords": [
            "Control strategy",
            "Grid-connected inverters",
            "Instantaneous power control scheme",
            "LCL filter",
            "Positive-sequence voltage detector"
        ],
        "venue": "Journal of Power Electronics",
        "year": 2013,
        "id": "5e7izINu"
    },
    "XTdhIsz8": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Linqiang Zhang",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Huaihua Li",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Jinqi Du",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Yanping Long",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Bo Liao",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            }
        ],
        "title": "Negative component compensation control scheme for photovoltaic grid-connected inverter",
        "abstract": "According to the grid current distortion on the photovoltaic (PV) grid-connected inverter side during grid unbalance, we proposed a negative sequence component compensation unbalanced control strategy based on d-q reference frame to suppress the current on grid-connected inverter side. After analyzing the mathematical model of unbalanced grid, the relationship of positive and negative sequences voltage components in d-q reference frame before and after an phase fault was demonstrated, and then a band-pass filter based on second-order generalized integrator (SOGI) was used to obtain the positive-negative sequence component to compensate the voltage and to form a new d-q reference voltage. The proposed method can suppress current harmonics, eliminate grid current distortion, and make the grid current within its rated value to avoid the PV system disconnecting from power grid. Further simulation and experiments results confirm the validity and efficacy of the proposed strategy.",
        "keywords": [
            "A phase voltage fault",
            "D-q rotating reference frame",
            "Negative component compensation",
            "Photovoltaic inverter",
            "Second-order generalized integrator band-pass filter",
            "SOGI BPF",
            "Unbalanced grid faults"
        ],
        "venue": "Gaodianya Jishu/High Voltage Engineering",
        "year": 2013,
        "id": "XTdhIsz8"
    },
    "KcDZI1Wi": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "State Key Lab. of Transmission and Distribution Equipment and Power System Safety and New Technology"
            },
            {
                "name": "Jin-Qi Du",
                "org": "State Key Lab. of Transmission and Distribution Equipment and Power System Safety and New Technology"
            },
            {
                "name": "Huai-Hua Li",
                "org": "State Key Lab. of Transmission and Distribution Equipment and Power System Safety and New Technology"
            },
            {
                "name": "Bo Liao",
                "org": "State Key Lab. of Transmission and Distribution Equipment and Power System Safety and New Technology"
            },
            {
                "name": "Yan-Ping Long",
                "org": "State Key Lab. of Transmission and Distribution Equipment and Power System Safety and New Technology"
            },
            {
                "name": "Lin-Qiang Zhang",
                "org": "State Key Lab. of Transmission and Distribution Equipment and Power System Safety and New Technology"
            }
        ],
        "title": "Harmonic and interharmonic measurement methods based on IEC standard and all-phase spectrum analysis",
        "abstract": "The new harmonic and interharmonic measurement method with good measuring accuracy for non-stationary signals under synchronous sampling is recommended by IEC 61000-4-7:2002 standard, but it shows poor measuring accuracy under asynchronous sampling, and the results are variable when relative phase of harmonic and interharmonic changes. To make up the deficiency above, this paper presents an advanced method which combines IEC standard framework with all-phase FFT. The method has the excellent property of inhibiting spectral leakage and the feature of phase invariance of all-phase FFT for detecting various typical non-stationary signals, and then is compared with the IEC method and IEC order cosine window method. Simulation results demonstrate that the advanced method is suitable for harmonic and interharmonic measurement for asynchronous sampling, even though the relative phase of harmonic and interharmonic changes, the measurement results are still with high accuracy and keep constant.",
        "keywords": [
            "All-phase spectrum analysis",
            "Asynchronous sampling",
            "Harmonic and interharmonic detection",
            "IEC standard",
            "Nonstationary signals"
        ],
        "venue": "Dianli Xitong Baohu yu Kongzhi/Power System Protection and Control",
        "year": 2013,
        "id": "KcDZI1Wi"
    },
    "xUwzJQ0A": {
        "authors": [
            {
                "name": "Ke Guo",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Yanping Long",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            }
        ],
        "title": "The progress and trend of research on bifurcation and chaos in H-bridge converter",
        "abstract": "The research actuality of the bifurcation and chaos phenomena in the H-bridge converter is summarized. Two discrete models of the typical H-bridge converter are introduced in detail, and their applicability is also analyzed and assessed. The existing stability analysis approaches and the numerical simulation methods used in the nonlinear study of H-bridge converter are analyzed concretely, and the merits and demerits are also summarized. With the method of Lyapunov exponent, those two discrete models are verified, and the difference between them, which are changeable according to the switching frequency, is analyzed and explained in detail. The application of time-delayed feedback control (TDFC) method and extended time-delayed feedback control method (ETDFC), which are used to control the chaos in H-bridge converter, is introduced, and their superiorities and deficiencies are evaluated. Finally, several future researches on the bifurcation and chaos phenomena of H-bridge converter are proposed, which provides some instructions for follow-up study.",
        "keywords": [
            "Bifurcation",
            "Chaos",
            "Chaos controlling",
            "Discrete model",
            "H-bridge converter"
        ],
        "venue": "Chongqing Daxue Xuebao/Journal of Chongqing University",
        "year": 2013,
        "id": "xUwzJQ0A"
    },
    "jv3AMb9c": {
        "authors": [
            {
                "name": "Yiyun Yang",
                "org": "Electric Power Research Institute of Guangxi Power Grid Company"
            },
            {
                "name": "Bo Liao",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Yang Chao",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Chuantao Si",
                "org": "Electric Power Research Institute of Guangxi Power Grid Company"
            }
        ],
        "title": "An approach to obtain reference sinusoidal signal for grid-connected inverter without phase-locked loop",
        "abstract": "It is necessary for grid-connection of distributed generation system to make the inverter output current strictly kept the same frequency and phase as those of grid voltage, thus the key point is to obtain the reference sinusoidal signal that is synchronic to power grid. Since in actual grid-connected system the grid voltage distortion and grid frequency deviation seriously affect the accuracy of reference sinusoidal signal detected by phase-locked loop (PLL), an approach to obtain reference sinusoidal signal is proposed, in which only single-phase voltage is utilized to attain the reference sinusoidal signal with the same frequency and phase angle as those of grid voltage without PLL. The sinusoidal signal obtained by the proposed approach is not affected by the distortion, multi-times of zero-crossing and unbalance of grid voltage. To ensure the effectiveness of the proposed algorithm, the initial value of second-order low-pass active filter should be set to extract low-frequency signal. The feasibility of the proposed method is verified by simulation results and experimental results.",
        "keywords": [
            "Grid-connected system",
            "Reference sinusoidal signal",
            "Voltage distortion",
            "With the same frequency and phase angle"
        ],
        "venue": "Dianwang Jishu/Power System Technology",
        "year": 2013,
        "id": "jv3AMb9c"
    },
    "ppmsbsin": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Yanping Long",
                "org": ""
            },
            {
                "name": "Ke Guo",
                "org": ""
            },
            {
                "name": "Huaihua Li",
                "org": ""
            },
            {
                "name": "Jinqi Du",
                "org": ""
            }
        ],
        "title": "Bifurcation and chaos of inverter system based on coefficient linear model",
        "abstract": "With the inverter with LC filter as the research subject, the bifurcation occurred in second order inverter system is studied. A discrete model with coefficient linearization based on traditional modeling method is provided to reduce the complexity of second order system and simplify the operations of system modeling, stability analysis and numerical simulation. The Jacobian matrix stability analysis is applied to analyze the differences between two models and achieve the stability region of system with single or double parameters. Numerical simulation indicates that, with the simplified model, the system stability region can be obtained effectively, much better than that with traditional model in complexity, operation load and speed.",
        "keywords": [
            "Bifurcation(mathematics)",
            "Chaos theory",
            "Coefficient linearization",
            "Discrete model",
            "Electric inverters",
            "Jacobian matrices",
            "Stability",
            "Stability region"
        ],
        "venue": "Dianli Zidonghua Shebei/Electric Power Automation Equipment",
        "year": 2013,
        "id": "ppmsbsin"
    },
    "c0n47Xo9": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Yang Chao",
                "org": ""
            },
            {
                "name": "Bo Liao",
                "org": ""
            },
            {
                "name": "Pengfei Chao",
                "org": ""
            },
            {
                "name": "Ming Yang",
                "org": ""
            }
        ],
        "title": "A voltage regulation strategy by grid-connected PV inverters in low-voltage networks",
        "abstract": "In allusion to out-of-limit voltage at grid-connected point caused by grid-connection of photovoltaic (PV) system and raising the penetration rate of PV system on power grid, it is possible to fully utilize the reactive power regulation ability of grid-connected PV inverter to provide reactive power support to power grid. For this purpose, in the viewpoint of voltage drop the voltage variation at grid-connected point before and after the grid-connection of PV system is researched, and the reactive power control strategy given by Verband Deutscher Elektrotechniker (VDE) is analyzed in depth. On this basis, a reactive power control strategy based on voltage amplitude at grid-connected point and active output of PV system is proposed. This control strategy inherits the advantages of reactive power control strategy given by VDE, and under the proposed control strategy all PV inverters participate power grid voltage regulation, and under the premise of maintaining the grid voltage within the specified range the total absorbed amount of reactive power is the lowest and the active and reactive loss of power grid are minimized. The validity of the proposed control strategy is verified by case study results.",
        "keywords": [
            "Low-voltage network",
            "Out-of-limit voltage",
            "PV inverters",
            "Reactive power control"
        ],
        "venue": "Dianwang Jishu/Power System Technology",
        "year": 2013,
        "id": "c0n47Xo9"
    },
    "5vHROEYF": {
        "authors": [
            {
                "name": "Ming Yang",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Dongxia Zhang",
                "org": "AFRA"
            },
            {
                "name": "Mi Zhang",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            }
        ],
        "title": "Stability analysis of large-scale photovoltaic power plants for the effect of grid impedance",
        "abstract": "Harmonic problem of the grid-connected inverters was detected in many large-scale photovoltaic(PV) plants and the harmonic problem may occurred even if all the PV inverters do individually satisfy the standards. For these reasons, the effect of grid impedance is considered, and the equivalent circuit model of three-phase grid-connected parallel inverters with LCL filter is established based on the basic structure and operating principle of the PV plants. According to the established equivalent circuit model, the influence of grid impedance in the current control loop is analyzed. Theoretical analysis indicates that grid-connected parallel inverters in PV plants are coupled due to the grid impedance, and the coupling effect can destabilize the inverter current control loop and lead to harmonic content overweight. Moreover, this study is validated by means of simulation and experiment results.",
        "keywords": [
            "Grid impedance",
            "Grid-connected inverters",
            "Large-scale photovoltaic plants",
            "Power quality",
            "Stability"
        ],
        "venue": "Diangong Jishu Xuebao/Transactions of China Electrotechnical Society",
        "year": 2013,
        "id": "5vHROEYF"
    },
    "og1KsBTf": {
        "authors": [
            {
                "name": "Yi-Yun Yang",
                "org": "Electric Power Research Institute of Guangxi Power Grid Corporation"
            },
            {
                "name": "Chuan-Tao Si",
                "org": "Electric Power Research Institute of Guangxi Power Grid Corporation"
            },
            {
                "name": "Bo Liao",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            }
        ],
        "title": "Positive-sequence fundamental wave extractor applied in the PV grid-connected power conditioning system",
        "abstract": "The key for PV grid-connected power conditioning system to realize the uniform control of PV grid-connected and active filter is to correctly detect harmonic and reactive current and form grid-connected directive current. Considering distortion and frequency deviation of the actual grid voltage, to get the correct harmonic, reactive current and synchronous sine, the amplitude integral and selective characteristic of frequency are used to form the positive sequence fundamental extractor. The K in the positive sequence fundamental extractor is further analyzed, and then the operation expression of K is derived. If K is chosen properly, positive-sequence fundamental can be got correctly, and synchronous sine and cosine can be got without the phase lock loop. The detecting method for the harmonic, reactive power, and the sum of unsymmetrical components, as well as the grid-connected directive current composing method is analyzed to realize the active power injection, harmonic eliminating and reactive power compensation. The simulation in Matlab/Simulink verifies the correctness of the theoretical analysis. For the effect of K on the positive-sequence fundamental extracting, the miniwatt experiment is conducted to further verify the correctness of the method.",
        "keywords": [
            "Directive current composing",
            "Grid-connected photovoltaic power conditioning system",
            "Harmonic detecting",
            "Parameter K",
            "Positive sequence fundamental wave extractor"
        ],
        "venue": "Dianli Xitong Baohu yu Kongzhi/Power System Protection and Control",
        "year": 2013,
        "id": "og1KsBTf"
    },
    "QH568R5F": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Mi Zhang",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Xiuli Ju",
                "org": "China Electric Power Research Institute"
            },
            {
                "name": "Guoqing He",
                "org": "China Electric Power Research Institute"
            }
        ],
        "title": "Stability analysis of large-scale photovoltaic plants due to grid impedances",
        "abstract": "The grid-connected photovoltaic (PV) system will become unstable when the grid impedance is large, especially when the large-scale PV plant was connected to a weak grid. In this paper, a Norton equivalent model of the three-phase paralleled inverters was established to study the stability of the large-scale grid-connected PV system including the grid impedance. The expression of the grid-connected current, the point of the common coupling (PCC) voltage and the closed loop characteristic equation of the system were derived. Then the stability of the large-scale grid-connected PV system was analyzed by the root locus. Finally, the study was validated through simulations. Studies show that there is no inter-phase coupling effect in the Norton equivalent model of the three-phase paralleled inverters, and the three-phase paralleled inverters can be converted to the single-phase paralleled inverters in order to study the characteristics. The large-scale grid-connected PV system will be unstable in some parameter regions depending on the grid impedance. \u00a9 2013 Chin. Soc. for Elec. Eng.",
        "keywords": [
            "Grid impedance",
            "Large-scale photovoltaic (PV) plants",
            "Norton equivalent model",
            "Paralleled inverters",
            "Stability"
        ],
        "venue": "Zhongguo Dianji Gongcheng Xuebao/Proceedings of the Chinese Society of Electrical Engineering",
        "year": 2013,
        "id": "QH568R5F"
    },
    "eJ1PZHNt": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            },
            {
                "name": "Mi Zhang",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology"
            }
        ],
        "title": "Modeling and stability of large-scale PV plants due to grid impedance",
        "abstract": "Grid-connected photovoltaic(PV) system will become unstable when the grid impedance(L",
        "keywords": [
            "grid impedance",
            "large-scale PV plants",
            "Norton equivalent model",
            "paralleled inverters",
            "stability"
        ],
        "venue": "IECON Proceedings (Industrial Electronics Conference)",
        "year": 2013,
        "id": "eJ1PZHNt"
    },
    "Zr9fVC5g": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Yang Chao",
                "org": ""
            },
            {
                "name": "Bo Liao",
                "org": ""
            },
            {
                "name": "Wei Ren",
                "org": ""
            },
            {
                "name": "Ming Yang",
                "org": ""
            },
            {
                "name": "Qiang Liu",
                "org": ""
            }
        ],
        "title": "A real-time detecting method for grid synchronization signals based on reference frequency",
        "keywords": [
            "Correction",
            "Frequency fluctuation",
            "Grid synchronization signal",
            "Phase deviation",
            "Reference frequency"
        ],
        "venue": "Zhongguo Dianji Gongcheng Xuebao/Proceedings of the Chinese Society of Electrical Engineering",
        "year": 2014,
        "id": "Zr9fVC5g"
    },
    "vLqHRls7": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Yanping Long",
                "org": ""
            },
            {
                "name": "Mi Zhang",
                "org": ""
            },
            {
                "name": "Yang Chao",
                "org": ""
            },
            {
                "name": "Guanghui Zheng",
                "org": ""
            }
        ],
        "title": "Analysis of low frequency oscillation in single-phase grid-connected inverter",
        "abstract": "The oscillation phenomenon in single-phase grid-connected inverter with LCL filter is analyzed. MATLAB/Simulink simulation is performed based on the average model of system, which shows that, the oscillation phenomenon occurs in a stable system along with the change of regulating coefficient. The discrete model of grid-connected inverter is deduced by using the stroboscopic sampling method. The system stability is analyzed according to the eigenvalues of Jacobian matrix, which reveals that the Hopf bifurcation occurred in system causes the oscillation phenomenon. The bifurcation point is accurately predicted by analyzing the change of eigenvalues. A method combined with the characteristic equation is given to determine the oscillation frequency. The correctness and validity of theoretical analysis are verified by experiments.",
        "keywords": [
            "Discrete model",
            "Electric filters",
            "Grid-connected inverter",
            "Hopf bifurcation",
            "Oscillation frequency"
        ],
        "venue": "Dianli Zidonghua Shebei/Electric Power Automation Equipment",
        "year": 2014,
        "id": "vLqHRls7"
    },
    "CwmDoSCt": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Beijing Institute of Technology"
            },
            {
                "name": "Geng-Guang Xu",
                "org": "Beijing Institute of Technology"
            }
        ],
        "title": "Configuration of underwater energy output for aluminized explosive mixtures",
        "abstract": "Underwater energy output characteristics of the different explosives has been indicatad through its parameters. The effect of aluminum on the underwater power of explosive mixtures was discussed. The result was proved that if the underwater shock wave energy can be close to the maximum Al/O ratio range for 0. 35\u223c 0. 40. When Al/O ratio is 1. 00, the underwater bubble energy can reach to the highest. The method can make the underwater energy output structure of explosion device each other mates valnembility of explosion objeitive, the damage effect of underwater detonation can be raised.",
        "keywords": [
            "Aluminums explosive",
            "Bubble energy",
            "Energy output",
            "Shock wave",
            "Underwater detonation"
        ],
        "venue": "Huozhayao Xuebao/Chinese Journal of Explosives and Propellants",
        "year": 2003,
        "id": "CwmDoSCt"
    },
    "4f1Ctkyq": {
        "authors": [
            {
                "name": "G.D. Kozak",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            }
        ],
        "title": "Spin Pulsating Detonation of Cast Charges",
        "abstract": "Quite distinct inhomogeneity of the detonation front was found earlier at detonation of cast charges: TNT-RDX, TNT-PETN, and liquids: Nitromethane, solution of DNT in DINA. Cast TNT-DINA, DNT-PETN and pressed HMX-paraffin charges were investigated in this respect later. The ultimate objective of this work is to extend the number of explosive systems capable of propagating detonation in the spin-pulsating regime, and to generalize the results of these investigations. Detonation velocity and heat of explosion were calculated and found to be the same for all the systems, detonated in low frequency (1-3 MHz) spin regime: D\n                        ",
        "keywords": [
            "Cast charge",
            "Detonation",
            "Spin pulsating"
        ],
        "venue": "Proceedings of the 2003 International Autumn Seminar on Propellants, Explosives and Pyrotechnics (2003 IASPEP) - Theory and Practice of Energetic Materials",
        "year": 2003,
        "id": "4f1Ctkyq"
    },
    "9CRTVuzj": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "LAB of Prevent and Control of Explosion Disaster"
            },
            {
                "name": "Hong-Ming Liu",
                "org": "LAB of Prevent and Control of Explosion Disaster"
            },
            {
                "name": "Geng-Guang Xu",
                "org": "LAB of Prevent and Control of Explosion Disaster"
            }
        ],
        "title": "Three-dimensional finite difference model of simulating the process of laser ignition of explosive",
        "abstract": "Based on the mechanism of thermal ignition of energetic materials, a three-dimensional finite difference model describing the process of laser ignition of explosive is established. With the help of this method, the growth process of surface temperature of RDX. HMX and PETN samples and composite B ignited by laser beam and contour of temperature in the samples and explosion induction time of samples are obtained by numerical simulation method. The results show that the calculated values of induction time obtained by three dimensional model are in agreement with the experimental data. The temperature growth mainly takes place in the surface layer of cylindrical sample irradiated by laser. The beam radius and pulse width of laser and absorption coefficient of the investigated samples to laser are some principal factors affecting the ignition energy threshold.",
        "keywords": [
            "Explosive",
            "Function time",
            "Laser ignition",
            "Numerical simulation",
            "Three-dimensional finite difference model"
        ],
        "venue": "Huozhayao Xuebao/Chinese Journal of Explosives and Propellants",
        "year": 2004,
        "id": "9CRTVuzj"
    },
    "1uRCVDFy": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Lab. for the Prevention and Control of Explosion Disasters"
            },
            {
                "name": "Ying-Qiang Liao",
                "org": "Lab. for the Prevention and Control of Explosion Disasters"
            },
            {
                "name": "Geng-Guang Xu",
                "org": "Lab. for the Prevention and Control of Explosion Disasters"
            }
        ],
        "title": "Experimental measurement of conductivity for the detonation product",
        "abstract": "Electrical conductivity measurement for the detonation product is put forward by means of measuring the electrical conductivity of detonation product for the composite explosive composed of HMX and TNT. Experimental results indicate that the electrical conductivity of aluminized explosive is obviously higher than that of the explosive without aluminium. TNT's (density 1.520 g\u00b7cm\n                        ",
        "keywords": [
            "Aluminium",
            "Applied physics",
            "Detonation product",
            "Electrical conductivity",
            "Explosion temperature",
            "HMX"
        ],
        "venue": "Hanneng Cailiao/Energetic Materials",
        "year": 2005,
        "id": "1uRCVDFy"
    },
    "ixh6bjju": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Shao-Hui Xu",
                "org": ""
            },
            {
                "name": "Geng-Guang Xu",
                "org": ""
            }
        ],
        "title": "Research on energy output characteristics for underwater explosion of explosives",
        "abstract": "The underwater explosion parameters including shock wave energy, bubble energy, shock wave pressure and factors (k and \u03b1) of shock wave pressure of the different underwater weapons were measured, calculated and analyzed by the detonation parameters of different typical explosives. The experimental result is very consistent with the calculated one. The calculation formula of \u03b1 for shock wave pressure was firstly found, providing the scientific basis for the underwater explosive formulation designs, warhead designs and performance evaluation of explosives.",
        "keywords": [
            "Bubble energy",
            "Explosion heat",
            "Explosive mechanics",
            "Shock wave energy",
            "Underwater explosion"
        ],
        "venue": "Binggong Xuebao/Acta Armamentarii",
        "year": 2006,
        "id": "ixh6bjju"
    },
    "H8niXwGx": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Explosion Science and Technology"
            },
            {
                "name": "Qi-Xian Yang",
                "org": "No.705 Research Institute"
            }
        ],
        "title": "The effect of Al/O ratio on underwater explosion shock wave of aluminium-containing explosives",
        "abstract": "The underwater explosion parameters (shock wave energy, bubble energy and assemble energy) of two kinds of aluminum-containing explosives (RDX/Al/Wax and AP/RDX/Al) were measured in the experiments. The Al/O ratios of the explosives were calculated. It has been found that the shock wave energies of the two explosives are maximized underwater when the Al/O ratio is about 0.4. In addition, the effect of Al/O ratio of RDX/TNT/Al/Wax explosive on the underwater shock wave energy was calculated and analyzed, and the same influencing law mentioned above was obtained. The research results show that the sequence of the explosives with maximum shock wave energies is AP/RDX/Al, RDX/Al/Wax and RDX/TNT/Al/Wax. The laws offer a scientific foundation to the compositions design of explosives for underwater weapons.",
        "keywords": [
            "Al/O ratio",
            "Bubble energy",
            "Explosion mechanics",
            "Shock wave energy",
            "Underwater explosion"
        ],
        "venue": "Binggong Xuebao/Acta Armamentarii",
        "year": 2008,
        "id": "H8niXwGx"
    },
    "1DcMXNxM": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Explosion Science and Technology"
            },
            {
                "name": "Zhong-Yuan Xie",
                "org": "Key Laboratory of Explosion Science and Technology"
            },
            {
                "name": "Qing-Xin Shao",
                "org": "Key Laboratory of Explosion Science and Technology"
            }
        ],
        "title": "Electrical conductivity of combustion products of composite propellant containing Cs salt",
        "abstract": "The electrical conductivity of combustion products of composite propellant containing Cs salt which used in magneto-hydro-dynamic (MHD) generator were calculated through Sahe equation and model of electrical conductivity. The basic thermodynamic parameters used in the model of electrical conductivity were calculated by applying thermodynamic equilibrium constant equation. Through theoretical calculation, the change of electrical conductivity along with the Cs salt content and aluminum content was obtained. The results show that for the given aluminum content, the optimal range of Cs salt content (mass percent) is 5%-10%; the higher combustion temperature and lower pressure of combustion chamber promote higher electrical conductivity.",
        "keywords": [
            "Applied physics",
            "Combustion temperature",
            "Composite propellant containing Cs salt",
            "Electrical conductivity",
            "Electron number density"
        ],
        "venue": "Hanneng Cailiao/Chinese Journal of Energetic Materials",
        "year": 2009,
        "id": "1DcMXNxM"
    },
    "7Q3RLkcs": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Explosion Science and Technology"
            },
            {
                "name": "Zhong-Yuan Xie",
                "org": "State Key Laboratory of Explosion Science and Technology"
            },
            {
                "name": "Yong Chen",
                "org": "China Shipbuilding Industry Corporation The 705th Research Institute Kunming"
            }
        ],
        "title": "An engineering calculation method on the bubble pulse period of underwater explosion",
        "abstract": "Based on the experiment research of former scientists, an engineering calculation method on the bubble pulse period of underwater explosion was established by introducing the correction factors of cylindrical and spherical charge forms into the relationship between explosion heat and bubble pulse period was revealed, and the exact calculation was realized by the method at the different explosives and charge forms. The method was verified by an experiment. The error of results between the experimented and the calculated is smaller than 5%. The method provides important science basis for designing formulation and evaluating performance of underwater explosive.",
        "keywords": [
            "Bubble period",
            "Explosion heat",
            "Mechanics of explosion",
            "Underwater explosion"
        ],
        "venue": "Binggong Xuebao/Acta Armamentarii",
        "year": 2009,
        "id": "7Q3RLkcs"
    },
    "X2yiyb92": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Yao-Liang Song",
                "org": ""
            },
            {
                "name": "Zhong-Yuan Xie",
                "org": ""
            },
            {
                "name": "Ming Hao",
                "org": ""
            }
        ],
        "title": "Research on the novel generating and transmitting techniques of high power electromagenatic impulse",
        "abstract": "High power electromagnetic impulse generating is a technology with wide applications in geophysical research, geologic exploration, petroleum recovery, ECCM and microwave weapon area. Based on traditional MHD system and modern MHD, the high power impulse forming and transmitting technique was discussed, the transform technique and implementing circuits of the high power multiple impulses from the single low voltage impulse was investigated, the experimental result was given and the key implementing the system was expounded.",
        "keywords": [
            "Electromagnetics",
            "Electronic counter-counter measures",
            "Impulse magnetohydrodynamics power generation",
            "Pulse forming"
        ],
        "venue": "Binggong Xuebao/Acta Armamentarii",
        "year": 2009,
        "id": "X2yiyb92"
    },
    "CZ9BIhZp": {
        "authors": [
            {
                "name": "Zhong-Yuan Xie",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            }
        ],
        "title": "Experimental study on propellant driven magnetohydrodynamic generator",
        "abstract": "Experiments have been set up respectively to study on the propellant formula, magnetohydrodynamic (MHD) channel and magnetic facility, of which all were applied in MHD generator. Then the MHD generator was manufactured in laboratory and the output voltage was test. Experimental results show that the solid composite propellant with cesium nitrate (CsNO",
        "keywords": [
            "Magnetic induction",
            "Magnetohydrodynamic channel",
            "Propellant",
            "Pulse magnetohydrodynamic generator"
        ],
        "venue": "Beijing Ligong Daxue Xuebao/Transaction of Beijing Institute of Technology",
        "year": 2011,
        "id": "CZ9BIhZp"
    },
    "aNwm1tTR": {
        "authors": [
            {
                "name": "Zhong-Yuan Xie",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            }
        ],
        "title": "Research on the strong magnetic field for pulse MHD generator",
        "abstract": "Aimed at the especial requirements for strong magnetic field in pulse MHD generator, a new scheme of magnetic circuit with soft iron was presented to obtain high and uniform magnetic flux density in a large volume. The flux density in a region was calculated by using Maxwell 2D/3D simulation software and the influences of soft iron, magnet material and other factors on the magnetic field were analyzed. The simulation results show that the soft iron can increase the flux density by 21.4% and improve the magnet field uniformity by 2%, compared with no soft iron, the soft iron thickness has an optimum value, and the increase of magnet inner coercive force can enhances the magnet flux density evidently. A magnet of 104 mm\u00d7360 mm\u00d7500 mm for pulse MHD generator was manufactured and installed in laboratory. The test results show that the average magnet flux density can be up to 1.24 T and the uniformity of magnet field exceeds 95%.",
        "keywords": [
            "Electrical engineering",
            "Magnet_condensing technology",
            "Pulse MHD generator",
            "Rotation theorem"
        ],
        "venue": "Binggong Xuebao/Acta Armamentarii",
        "year": 2011,
        "id": "aNwm1tTR"
    },
    "DRugHOrT": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Explosion Science and Technology"
            },
            {
                "name": "Zhongyuan Xie",
                "org": "State Key Laboratory of Explosion Science and Technology"
            },
            {
                "name": "Xuexia Wei",
                "org": "State Key Laboratory of Explosion Science and Technology"
            }
        ],
        "title": "Comparison of underwater shock wave attenuation of a new insensitive high explosive with different explosives",
        "abstract": "A series of experiments is performed to compare underwater shock wave attenuation of a new insensitive and aluminized high explosive RS with TNT, JH14, and PBXN- 111 explosives. A new model with a uniform expression is proposed to characterize the pressure-time histories of the explosives. Numerical results show that the new model is applicable for both aluminized explosives and ideal explosives. The correlation coefficients for fitted curves are verified by thousands of test data for different explosives, and the accuracy is above 0.99. The energy of the underwater shock wave generated by PBXN-111 and TNT characterized by the new model agrees well with available experimental results. In addition, the shock energy of the new insensitive and aluminized high explosive RS is higher than that of PBXN-11 by 13.4%. The general performance of underwater shock wave attenuation of the insensitive and aluminized high explosive RS is found to be better than that of TNT, JH14, and PBXN-111 explosives. \u00a9 2011 by Pleiades Publishing, Ltd.",
        "keywords": [
            "New insensitive high explosive",
            "Shock wave attenuation",
            "Underwater explosion"
        ],
        "venue": "Combustion, Explosion and Shock Waves",
        "year": 2011,
        "id": "DRugHOrT"
    },
    "Mu7CStjE": {
        "authors": [
            {
                "name": "Jinyou Shen",
                "org": ""
            },
            {
                "name": "Zongyuan Zhou",
                "org": ""
            },
            {
                "name": "Changjin Ou",
                "org": ""
            },
            {
                "name": "Xiuyun Sun",
                "org": ""
            },
            {
                "name": "Jiansheng Li",
                "org": ""
            },
            {
                "name": "Weiqing Han",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Lianjun Wang",
                "org": ""
            }
        ],
        "title": "Reductive transformation and detoxification mechanism of 2,4-dinitrochlorobenzene in combined zero valent iron and anaerobic-aerobic process",
        "abstract": "A combined zero valent iron (ZVI) and anaerobic-aerobic process was adopted for the treatment of 2,4-dinitrochlorobenzene (DNCB)-containing wastewater. The transformation pathway, reduction of acute toxicity and enhancement of biodegradability were investigated. After pretreatment by ZVI, DNCB in wastewater could be completely converted into 2,4-diaminochlorobenzene (DACB). The ratio of BOD",
        "keywords": [
            "2,4-dinitrochlorobenzene",
            "Biodegradability",
            "Toxicity",
            "Zero-valent iron"
        ],
        "venue": "Journal of Environmental Sciences (China)",
        "year": 2012,
        "id": "Mu7CStjE"
    },
    "TyXOmO61": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Explosion Science and Technology"
            },
            {
                "name": "Qing-Ming Zhang",
                "org": "State Key Laboratory of Explosion Science and Technology"
            },
            {
                "name": "Guang-Fu Ji",
                "org": "Laboratory for Shock Wave and Detonation Physics Research"
            },
            {
                "name": "Zi-Zheng Gong",
                "org": "National Key Laboratory of Science and Technology on Reliability and Environment Engineering"
            }
        ],
        "title": "First principle study for the melting properties of face-centred-cubic aluminum",
        "abstract": "Ab initio electronic structure optimization and total energy calculations for fcc aluminum are used to study the equation of state (EOS).Through fitting to quasi-harmonic Debye model, the thermodynamics properties of different temperatures are calculated. The melting curve at different pressures is presented based on Lindemann measures. The results show that the calculated EOS and the revised melting curve both are in a good agreement with the shock compression and the diamond-anvil-cell (DAC) data. The results illustrate that we can use simple static calculation method which takes less time to gain reasonable melting results. It can be used in the qualitative forecast for materials with difficult experiments. \u00a9 (2013) Trans Tech Publications, Switzerland.",
        "keywords": [
            "Face-centred-cubic aluminum",
            "First principle",
            "Lindeman equation",
            "Melting curve",
            "Quasi-harmonic debye model",
            "Thermodynamic"
        ],
        "venue": "Key Engineering Materials",
        "year": 2013,
        "id": "TyXOmO61"
    },
    "IfhxXddV": {
        "authors": [
            {
                "name": "Jun-Jiong Meng",
                "org": "State Key Laboratory of Explosion Science and Technology"
            },
            {
                "name": "Xiang-Rong Zhang",
                "org": "State Key Laboratory of Explosion Science and Technology"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Explosion Science and Technology"
            }
        ],
        "title": "Simulation of solidification process for DNAN-based melt-cast explosives",
        "abstract": "In order to simulate the pouring and solidification process of DNAN based melt-cast explosives, flow and thermal fields were calculated using structured mesh, and stress field was calculated using unstructured mesh. This numerical scheme can obtain an accurate interface between solid and liquid, reasonable shrinkage and stress data. By comparison research, on the condition of certain mould and charge size, the optimized scheme for DNAN-based melt-cast explosives is that thermal insulation on upper mould surface for an hour with 30\u00b0C water on lower mould surface, in order to decrease shrinkage, thermal stress value and solidification time by overall consideration.",
        "keywords": [
            "Charge defect",
            "Melt-cast explosive",
            "Ordnance science and technology",
            "Rheology",
            "Structured and unstructured mesh"
        ],
        "venue": "Binggong Xuebao/Acta Armamentarii",
        "year": 2013,
        "id": "IfhxXddV"
    },
    "HRO8y9kN": {
        "authors": [
            {
                "name": "Jinyou Shen",
                "org": "Jiangsu Key Laboratory of Chemical Pollution Control and Resources Reuse"
            },
            {
                "name": "Changjin Ou",
                "org": "Jiangsu Key Laboratory of Chemical Pollution Control and Resources Reuse"
            },
            {
                "name": "Zongyuan Zhou",
                "org": "Jiangsu Key Laboratory of Chemical Pollution Control and Resources Reuse"
            },
            {
                "name": "Jun Chen",
                "org": "Hubei Dongfang Chemical Co. Ltd."
            },
            {
                "name": "Kexiong Fang",
                "org": "Hubei Dongfang Chemical Co. Ltd."
            },
            {
                "name": "Xiuyun Sun",
                "org": "Jiangsu Key Laboratory of Chemical Pollution Control and Resources Reuse"
            },
            {
                "name": "Jiansheng Li",
                "org": "Jiangsu Key Laboratory of Chemical Pollution Control and Resources Reuse"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Mechatronical Engineering"
            },
            {
                "name": "Lianjun Wang",
                "org": "Jiangsu Key Laboratory of Chemical Pollution Control and Resources Reuse"
            }
        ],
        "title": "Pretreatment of 2,4-dinitroanisole (DNAN) producing wastewater using a combined zero-valent iron (ZVI) reduction and Fenton oxidation process",
        "abstract": "A combined zero-valent iron (ZVI) reduction and Fenton oxidation process was tested for the pretreatment of 2,4-dinitroanisole (DNAN) producing wastewater. Operating conditions were optimized and overall performance of the combined process was evaluated. For ZVI process, almost complete reduction of nitroaromatic compounds was observed at empty bed contact time (EBCT) of 8h. For Fenton process, the optimal pH, H",
        "keywords": [
            "2,4-Dinitroanisole (DNAN)",
            "Fenton process",
            "Oxidation",
            "Reduction",
            "Zero-valent iron (ZVI)"
        ],
        "venue": "Journal of Hazardous Materials",
        "year": 2013,
        "id": "HRO8y9kN"
    },
    "R6zwPqDe": {
        "authors": [
            {
                "name": "Yuanyuan Ju",
                "org": "State Key Laboratory of Explosion Science and Technology"
            },
            {
                "name": "Qingming Zhang",
                "org": "State Key Laboratory of Explosion Science and Technology"
            },
            {
                "name": "Zizheng Gong",
                "org": "National Key Laboratory of Science and Technology on Reliability and Environment Engineering"
            },
            {
                "name": "Guangfu Ji",
                "org": "Laboratory for Shock Wave and Detonation Physics Research"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Explosion Science and Technology"
            }
        ],
        "title": "Molecular dynamics simulation of shock melting of aluminum single crystal",
        "abstract": "Molecular dynamics method in conjunction with multi-scale shock technique is employed to study the melting characteristics of aluminum single crystal under dynamic conditions. The simulated results show that a linear relationship exists between the shock wave velocity and particle velocity, in good agreement with the experimental data. Comparing the Lindemann melting curve with the two Hugoniot curves for the solid and liquid phases, the Hugoniot melting is found to begin at 93.6 GPa and end at 140 GPa, which is consistent with the theoretical calculations. The impact of crystal defects on the melting characteristics of aluminum single crystal is also studied, and the results indicate that the pressure and temperature increase slightly for the system experiencing the same dynamic loading due to the crystal defects. \u00a9 2013 AIP Publishing LLC.",
        "keywords": [
            ""
        ],
        "venue": "Journal of Applied Physics",
        "year": 2013,
        "id": "R6zwPqDe"
    },
    "cLJlBjQp": {
        "authors": [
            {
                "name": "Xian Grong Zhang",
                "org": "State Key Laboratory of Explosion Science and Technology"
            },
            {
                "name": "Xu Dan",
                "org": "State Key Laboratory of Explosion Science and Technology"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Explosion Science and Technology"
            }
        ],
        "title": "Numerical simulation of thermal sensitivity for explosives",
        "abstract": "In order to compare the thermal sensitivity of several typical explosives, this article solved numerically one-dimensional transient heat conduction equation including thermal decomposition for explosives with finite difference method. The explicit difference equations under different boundary conditions were established, and the corresponding stability criterion was derived. The ignition times for typical explosives were calculated, which was used to evaluate thermal sensitivity of explosives. \u00a9 (2013) Trans Tech Publications, Switzerland.",
        "keywords": [
            "Explosives",
            "Finite difference method",
            "Ignition time",
            "Thermal sensitivity"
        ],
        "venue": "Advanced Materials Research",
        "year": 2013,
        "id": "cLJlBjQp"
    },
    "sbSwHoOT": {
        "authors": [
            {
                "name": "Xiang Rong Zhang",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            }
        ],
        "title": "Effect of breakage on the bipolarly charged particles",
        "abstract": "The population balance equation (PBE) was solved numerically by using the sectional method to investigate the effect of breakage on the agglomeration between bipolarly charged particles. Calculations showed that breakage results in the increase of small particles and the decrease of large particles bipolarly charged, compared to the case with only agglomeration effect. The breakage effects are important when simulating the agglomeration dynamics. \u00a9 (2013) Trans Tech Publications, Switzerland.",
        "keywords": [
            "Bipolarly charged particles",
            "Breakage and agglomeration",
            "Population balance equation",
            "Sectional method"
        ],
        "venue": "Advanced Materials Research",
        "year": 2013,
        "id": "sbSwHoOT"
    },
    "iSEzlDj5": {
        "authors": [
            {
                "name": "Zhong-Yuan Xie",
                "org": "Xi'an Modern Chemistry Research Institute"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Explosion Science and Technology, Beijing Institute of Technology"
            },
            {
                "name": "Hao Wang",
                "org": "Xi'an Modern Chemistry Research Institute"
            },
            {
                "name": "Kai Zhao",
                "org": "Xi'an Modern Chemistry Research Institute"
            },
            {
                "name": "Yi-Ming Luo",
                "org": "Xi'an Modern Chemistry Research Institute"
            },
            {
                "name": "Hong-Liang Zhang",
                "org": "China Research and Development Academy of Machinery Equipment"
            }
        ],
        "title": "Combustion performance of boron coated with AP",
        "abstract": "In order to study the combustion performance of boron (B) coated with AP, the AP/B composite particles are prepared by solvent evaporation method. SEM is used to observe the surface morphology of coating layers. The CO",
        "keywords": [
            "AP coating layer",
            "AP/B composite particle",
            "Boron-containing explosive",
            "Combustion performance",
            "Explosion heat",
            "Ordnance science and technology"
        ],
        "venue": "Binggong Xuebao/Acta Armamentarii",
        "year": 2014,
        "id": "iSEzlDj5"
    },
    "FAPAoLTy": {
        "authors": [
            {
                "name": "Haoming Song",
                "org": "Department of Cardiology, Tongji Hospital, Tongji University School of Medicine"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Cardiology, Tongji Hospital, Tongji University School of Medicine"
            },
            {
                "name": "Wei Lv",
                "org": "Department of Cardiology, Tongji Hospital, Tongji University School of Medicine"
            },
            {
                "name": "Zhu Gong",
                "org": "Department of Cardiology, Tongji Hospital, Tongji University School of Medicine"
            },
            {
                "name": "Yuqin Shen",
                "org": "Department of Cardiology, Tongji Hospital, Tongji University School of Medicine"
            },
            {
                "name": "Lemin Wang",
                "org": "Department of Cardiology, Tongji Hospital, Tongji University School of Medicine"
            }
        ],
        "title": "Analysis of t cell immune function of 16 patients with chronic thromboembolic pulmonary hypertension",
        "abstract": "Aims: The aim of this study is to observe the T cell immune function in patients with chronic thromboembolic pulmonary hypertension (CTEPH). Materials and methods: Expressions of T cell surface antigens including CD3+, CD4+, CD8+ and CD4+/CD8+ ratio were examined in 16 patients with CTEPH, with a follow-up of 1 year. Follow-up data were acquired from 9 patients (56%). mRNA expression of T cell immunity related genes was measured by whole human genome microarray in peripheral blood mononuclear cells (PBMCs) of some patients and 20 controls. Results: Of 16 patients, 7 (44%) had abnormal CD3+ expression (2 were increased, 5 were decreased), 5 (31%) had increased CD4+ expression, 8 (50%) had decreased CD8+ expression, and 10 had abnormal CD4+/CD8+ ratio (8 were increased, 2 were decreased). Of 9 patients followed up, 7 (78%) had decreased CD3+ expression, 5 (55%) had abnormal CD4+ expression (1 was increased, 4 were decreased), 6 (67%) had decreased CD8+ expression, and 6 had increased CD4+/CD8+ ratio. When compared with controls, the mRNA expressions of CD3D, CD3G, GZMA, GZMB and ZAP70 were markedly down-regulated in 10 CTEPH patients (P<0.05). Conclusion: The T cell functions of antigen recognition, signal transduction and killing pathogens in patients with CTEPH were reduced, and T cell immune dysfunction may play an important role in the occurrence and development of CTEPH.",
        "keywords": [
            "Chronic thromboembolic pulmonary hypertension",
            "Pulmonary embolism",
            "RNA messenger",
            "T cell immune function"
        ],
        "venue": "Acta Medica Mediterranea",
        "year": 2015,
        "id": "FAPAoLTy"
    },
    "sZu9ngHS": {
        "authors": [
            {
                "name": "Zhong-Yuan Xie",
                "org": "Xi'an Modern Chemistry Research Institute"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Explosion Science and Echnology, Beijing Institute of Technology"
            },
            {
                "name": "Hao Wang",
                "org": "Xi'an Modern Chemistry Research Institute"
            },
            {
                "name": "Shou-Dian Li",
                "org": "Norincogroup Planning and Research Institute"
            }
        ],
        "title": "Application of genetic algorithm in calculation of combustion equilibrium composition",
        "abstract": "Genetic algorithm for the calculation of combustion equilibrium composition was proposed based on the principles of chemical equilibrium and the method of minimum free energy. By determining the independent variables and its range, the fitness function was confirmed. To validate the accuracy of the genetic algorithm, the calculation results were compared with the data from references experiment. Results show that the calculation values agree well with the reference data with error less than 1% and 1.5% for combustion equilibrium composition and combustion temperature of negative-oxygen compounds, and less than 7.7% and 5% for that of oxygen-enriched compounds. And the theoretic calculations are well coincident with those obtained by tests of hydroxyl-terminated polybutadiene solid Propellants. The maximum error between them is 4.27%, which demonstrates that the genetic algorithm can be used in compound design, performance prediction and combustion products confirming.",
        "keywords": [
            "Combustion",
            "Equilibrium composition",
            "Genetic algorithm",
            "Minimum free energy"
        ],
        "venue": "Hanneng Cailiao/Chinese Journal of Energetic Materials",
        "year": 2015,
        "id": "sZu9ngHS"
    },
    "38PRZcuA": {
        "authors": [
            {
                "name": "Fuyuan Peng",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Xuguang Yan",
                "org": ""
            },
            {
                "name": "Yanjun Chang",
                "org": ""
            }
        ],
        "title": "A novel underwater 3-D laser imaging system",
        "abstract": "A new system for underwater 3-D laser imaging is proposed in this paper, which utilizes gated-range technique to generate multi-distance images of underwater objects or seafloor landform. For reducing the influences on image of forward-scattering, we simulate the forward-scattering component by Monte Carlo method and analyse its temporal and frequency properties. The outcome is constructive significance to enhancing resolution and signal-to-noise ratio of the imaging system. In the reconstruction of real-time 3-D landform, an algorithm of sectional-cross interpolation which based on the random interation function system (IFS) is presented, which needs only a few points in two contours, and decreases greatly the quantities of information and computation required in the 3-D reconstruction, furthermore, contours generated by interpolation obtain fractal properties, the entire underwater 3-D laser imaging system is of real-time properties and practicable.",
        "keywords": [
            "Forward-scattering",
            "Laser technique",
            "Sectional-cross interpolation",
            "Underwater 3D imaging"
        ],
        "venue": "Progress in Environmental and Engineering Geophysics: Proceedings of the International Conference on Environmental and Engineering Geophysics, ICEEG 2004",
        "year": 2004,
        "id": "38PRZcuA"
    },
    "XNpzV15z": {
        "authors": [
            {
                "name": "Xiao Xiao",
                "org": ""
            },
            {
                "name": "Guangxi Zhu",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Yejun He",
                "org": ""
            }
        ],
        "title": "Study on multi-user diversity of V-BLAST/OFDM systems",
        "abstract": "In order to improve the performance of V-BLAST/OFDM systems. This paper proposed the dynamic subcarrier allocation rules. The rules can effectively use multi-user diversity to improve V-BLAST/OFDM systems' performance greatly. The performance gain was analyzed quantitatively with order statistics and random matrix theories, and the analysis was validated by the simulation results. Moreover, compared with spatial diversity system, the dynamic subcarrier allocation combined with V-BLAST/OFDM system is showed to improve the system performance.",
        "keywords": [
            "Multi-user diversity",
            "OFDM",
            "Spatial multiplexing",
            "Subcarrier allocation"
        ],
        "venue": "Gaojishu Tongxin/Chinese High Technology Letters",
        "year": 2007,
        "id": "XNpzV15z"
    },
    "pSc4ral8": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Bao-Ming Bai",
                "org": ""
            },
            {
                "name": "Jing Wang",
                "org": ""
            }
        ],
        "title": "Adaptive coded-modulation schemes based on CT-TCM",
        "abstract": "An ACM system based on concatenated two-state trellis-coded modulation (CT-TCM), which can achieve improved spectral efficiency at a given target bit-error-rate (BER) was proposed. A fixed-power variable-rate CT-TCM scheme was developed with an adaptive algorithm; moreover, a kind of LMS algorithm for channel estimation was presented based on the MAP decoding of CT-TCM. Simulation results show that, when R",
        "keywords": [
            "Adaptive coded modulation (ACM)",
            "Gallager mapping",
            "Least mean square algorithm",
            "Turbo trellis-coded modulation"
        ],
        "venue": "Tongxin Xuebao/Journal on Communications",
        "year": 2008,
        "id": "pSc4ral8"
    },
    "b3r2RJ1A": {
        "authors": [
            {
                "name": "Xiao Xiao",
                "org": ""
            },
            {
                "name": "Guangxi Zhu",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Desheng Wang",
                "org": ""
            },
            {
                "name": "Li Li",
                "org": ""
            }
        ],
        "title": "Analysis of maximal-ratio of transmitting/receiving antenna selection with perfect and partial channel information",
        "abstract": "To improve system performance and reduce the complexity and cost of receiver hardware, we investigated a new multiple-input multiple-output (MIMO) scheme combining maximal-ratio transmitting and receiver antenna selection (MRT/RAS). In this scheme, a single receiving antenna, which maximizes the signalto-noise ratio (SNR) at the receiver, is selected for demodulation. The closed-form outage probability and the bit error rate (BER) of the MRT/RAS system are both presented. The simulation demonstrates that the MRT/RAS scheme can achieve a full diversity order as if all the receiving antennas were used. It is shown that the MRT/RAS scheme outperforms some more complex space-time codes of the same spectral efficiency. The analytical results are verified by simulation. In the end, we also analyze the MRT/RAS system based on partial channel information. \u00a9 2008 Higher Education Press and Springer-Verlag GmbH.",
        "keywords": [
            "Antenna selection",
            "Diversity",
            "Maximal-ratio transmitting",
            "Multi-input multi-output (MIMO)"
        ],
        "venue": "Frontiers of Electrical and Electronic Engineering in China",
        "year": 2008,
        "id": "b3r2RJ1A"
    },
    "Rss14pcx": {
        "authors": [
            {
                "name": "Jun-Hu Shao",
                "org": "State Key Lab of Integrated Service Networks"
            },
            {
                "name": "Bao-Ming Bai",
                "org": "State Key Lab of Integrated Service Networks"
            },
            {
                "name": "Wei Lin",
                "org": "State Key Lab of Integrated Service Networks"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Lab of Integrated Service Networks"
            }
        ],
        "title": "Jointly-check iterative decoding algorithm for quantum sparse graph codes",
        "abstract": "For quantum sparse graph codes with stabilizer formalism, the unavoidable girth-four cycles in their Tanner graphs greatly degrade the iterative decoding performance with a standard belief-propagation (BP) algorithm. In this paper, we present a jointly-check iterative algorithm suitable for decoding quantum sparse graph codes efficiently. Numerical simulations show that this modified method outperforms the standard BP algorithm with an obvious performance improvement. \u00a9 2010 Chinese Physical Society and IOP Publishing Ltd.",
        "keywords": [
            "Belief-propagation algorithm",
            "Iterative decoding",
            "Quantum error correction",
            "Sparse graph code"
        ],
        "venue": "Chinese Physics B",
        "year": 2010,
        "id": "Rss14pcx"
    },
    "n53yEzcX": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Baoming Bai",
                "org": ""
            },
            {
                "name": "Ming Xu",
                "org": ""
            }
        ],
        "title": "Design of nonbinary rate-compatible LDPC codes utilizing bit-wise shortening method",
        "abstract": "Based on the algebraic properties of binary images corresponding to the nonbinary elements, we propose a construction of nonbinary rate-compatible low-density parity-check (RC-LDPC) codes at short block length by using bit-wise shortening method. Different from the traditional information-shortening methods, the shortened information bits in the proposed method are carefully chosen according to the degree distributions of their binary images. Simulations show that the performance of proposed method is close to that of uniform bit-wise shortening, and considerable gains can be attained over conventional symbol-wise shortening, random bit-wise shortening and their corresponding binary RC-LDPC codes. \u00a9 2006 IEEE.",
        "keywords": [
            "binary image",
            "bit-wise shortening",
            "Nonbinary low-density parity-check (LDPC) codes",
            "rate-adaptive",
            "rate-compatible (RC)"
        ],
        "venue": "IEEE Communications Letters",
        "year": 2010,
        "id": "n53yEzcX"
    },
    "YR6pjIGv": {
        "authors": [
            {
                "name": "Jun-Hu Shao",
                "org": "State Key Lab. of Integrated Service Networks"
            },
            {
                "name": "Bao-Ming Bai",
                "org": "State Key Lab. of Integrated Service Networks"
            },
            {
                "name": "Wei Lin",
                "org": "State Key Lab. of Integrated Service Networks"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Lab. of Integrated Service Networks"
            }
        ],
        "title": "Construction and decoding of nonbinary quantum LDPC codes",
        "abstract": "Nonbinary quantum codes are more suitable for error-correction in multi-level quantum systems. Based on stabilizer formalism over the finite field, a class of nonbinary quantum LDPC codes is presented in this paper. And the BP iterative decoding algorithm for these codes is described under the quantum depolarizing channel with the Monte Carlo simulation method. For example, a class of CSS structure 4-ary quantum LDPC codes is given with code rates 1/2 and 1/4. Compared with the present binary quantum LDPC codes of equivalent codelength, the channel threshold with 10-5FER is improved from 0.016 to 0.025.",
        "keywords": [
            "BP algorithm",
            "LDPC code",
            "Quantum information",
            "Quantum LDPC code"
        ],
        "venue": "Xi'an Dianzi Keji Daxue Xuebao/Journal of Xidian University",
        "year": 2010,
        "id": "YR6pjIGv"
    },
    "TVBhTCLR": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Baoming Bai",
                "org": ""
            },
            {
                "name": "Junhu Shao",
                "org": ""
            },
            {
                "name": "Wei Lin",
                "org": ""
            }
        ],
        "title": "On nonbinary rate-compatible LDPC codes",
        "abstract": "Two design methods for nonbinary rate-compatible LDPC (RC-LDPC) codes are proposed. And a novel irregular bit-wise shortening algorithm based on the algebraic properties of their binary images is proposed, with which we can obtain improved performance and extra flexibility; a symbol-wise puncturing algorithm for binary LDPC codes is extended to nonbinary LDPC codes. With these two algorithms, we obtain a family of nonbinary RC-LDPC codes with the code-rate range from 1/10 to 5/6. Simulation results demonstrate that gains of 0.1~1.1dB are obtained by proposed methods.",
        "keywords": [
            "Nonbinary LDPC codes",
            "Puncture",
            "Rate-compatible",
            "Shorten"
        ],
        "venue": "Xi'an Dianzi Keji Daxue Xuebao/Journal of Xidian University",
        "year": 2011,
        "id": "TVBhTCLR"
    },
    "GcBIEmJt": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Kan-Kan Wu",
                "org": ""
            },
            {
                "name": "Rui Zhao",
                "org": ""
            },
            {
                "name": "Can-Hui Cai",
                "org": ""
            },
            {
                "name": "Lin Wang",
                "org": ""
            }
        ],
        "title": "Design of shortened turbo product codes and their improved decoding",
        "abstract": "In this paper, a general matrix structure for shortened turbo product codes (TPC) and an improved decoding algorithm based on Chase decoder are presented. In the proposed algorithm, the decoding complexity is decreased by reducing the number of candidate codewords and, an efficient method to estimate the extrinsic information without competing codeword is designed, too. Compared with the conventional algorithm, simulation results show that considerable coding gains can be obtained by the proposed decoding algorithm with decreasing decoding complexity. \u00a9 2011 Published by Elsevier Ltd.",
        "keywords": [
            "Chase algorithm",
            "Iterative decoding",
            "Shortened turbo product codes"
        ],
        "venue": "Procedia Engineering",
        "year": 2011,
        "id": "GcBIEmJt"
    },
    "obG3hbSJ": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Lei Yu",
                "org": ""
            }
        ],
        "title": "Frequency-utilization based power-aware schedule policy for real-time multi-core system",
        "abstract": "With the global energy crisis, nowadays, high performance is no longer our only pursuit, Green Computing becomes another tendency in data center research. In this paper, we present a Frequency-Utilization based Power-Aware (FUPA) model for single CPU, then multi-cores system. A theoretical power optimized frequency for certain workload is deduced, and the optimized cores number is found. We realize the model in the GridSim simulator which proves the good performance and the power-saving capability of this approach. \u00a9 2013 IEEE.",
        "keywords": [
            "Distributed system",
            "Dynamic Voltage Scaling (DVS)",
            "Energy optimization",
            "Green computing",
            "Multi-cores",
            "Power-aware scheduling",
            "Soft real-time"
        ],
        "venue": "Proceedings - 2013 IEEE International Conference on Green Computing and Communications and IEEE Internet of Things and IEEE Cyber, Physical and Social Computing, GreenCom-iThings-CPSCom 2013",
        "year": 2013,
        "id": "obG3hbSJ"
    },
    "eF1f5hLi": {
        "authors": [
            {
                "name": "Shuai Yuan",
                "org": "National Numerical Control System Engineering Research Center"
            },
            {
                "name": "Fangyu Peng",
                "org": "National Numerical Control System Engineering Research Center"
            },
            {
                "name": "Lin Zhou",
                "org": "National Numerical Control System Engineering Research Center"
            },
            {
                "name": "Peifeng Yao",
                "org": "National Numerical Control System Engineering Research Center"
            }
        ],
        "title": "Analysis and modeling of the thermal errors of carriage system of a precision machine tool driven by linear motor",
        "abstract": "The drive system with linear motor of precision machine tools can generate a lot of heat and part of it is conducted to machine tools structures. Therefore, it can lead to the thermal deformation of the structures and hence seriously influences the processing accuracy. In this paper, the finite element model (FEM) considering convection of the planes, the pipelines of the cooler system and thermal resistance is adopted to investigate the thermal distribution and thermal deformation of the carriage system of precision machine tools driven by linear motor. In addition, position-independent thermal errors models of the carriage system are proposed for the main heat source, the primary part of the linear motor, of the carriage system travels with the worktable; the feature genetic algorithm is used to procure the thermal key points of the carriage due to the great number of candidate points. At last, the experiment is conducted on the Y-axis carriage system of precision three-axis machine tool, which demonstrates the two geometric errors \u03b4x and \u03b5z caused by the thermal deformation are significantly tiny. The mathematical models of three thermal errors are obtained through the temperatures of the key thermal points because the interferometer cannot measure the roll error \u03b5y. Also, the comparison between the measurements and the thermal errors models indicates that the position-independent thermal models are capable of satisfactorily predicting the magnitude of the other three geometric errors of the carriage system caused by the thermal deformation and also being used in further study of compensation system.",
        "keywords": [
            "Genetic algorithm",
            "Linear motor",
            "Thermal key points",
            "Thermal model"
        ],
        "venue": "Key Engineering Materials",
        "year": 2014,
        "id": "eF1f5hLi"
    },
    "Pyr81XDo": {
        "authors": [
            {
                "name": "Qi Li",
                "org": "State Key Laboratory of Integrated Services Networks, Xidian University"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Information Science and Engineering, Huaqiao University"
            },
            {
                "name": "Bo Zhang",
                "org": "No.96401 Troop"
            },
            {
                "name": "Bao-Ming Bai",
                "org": "Science and Technology on Information Transmission and Dissemination in Communication Networks Laboratory"
            }
        ],
        "title": "Simple constellation shaping for BICM-ID",
        "abstract": "A novel method of constellation mapping is presented for bit-interleaved coded modulation (BICM) by combining geometry shaping with probabilistic shaping. The transmitted signal points of a practical signal constellation approach the optimal input distribution by exploiting a many-to-one mapping with some signal points unused. With this method, shaping gain can be achieved conveniently with the help of iterative decoding between demodulation and decoder. The optimizations of signal constellation and the mapping from symbols to signal points are performed by the analysis of capacity and the extrinsic information transfer chart. Simulation results show that the proposed constellation mapping outperforms the traditional Gray mapping for BICM with iterative decoding in both AWGN and Rayleigh channels. And the shaping gain achieved can be improved with the increase of the constellation size.",
        "keywords": [
            "Bit-interleaved coded modulation",
            "Constellation mapping",
            "Extrinsic information transfer chart",
            "Iterative decoding",
            "Shaping gain"
        ],
        "venue": "Tongxin Xuebao/Journal on Communications",
        "year": 2015,
        "id": "Pyr81XDo"
    },
    "yL1vhcUb": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Lab. for Superhard Mat."
            },
            {
                "name": "Hongan Ma",
                "org": "Lab. for Superhard Mat."
            },
            {
                "name": "Yantao Li",
                "org": "Lab. for Superhard Mat."
            },
            {
                "name": "Qiang Hu",
                "org": "Lab. for Superhard Mat."
            },
            {
                "name": "Guozhong Ren",
                "org": "Lab. for Superhard Mat."
            },
            {
                "name": "Chuanyi Zang",
                "org": "Henan Univ. of Technol."
            },
            {
                "name": "Xiaopeng Jia",
                "org": "Henan Univ. of Technol."
            }
        ],
        "title": "Synthesis of diamond using powder catalyst with sulphur additive",
        "abstract": "In this paper, high quality diamond crystals were synthesized respectively using Fe-Ni catalyst and Sulfur-added Fe-Ni catalyst in cubic anvil high-pressure apparatus. The synthesized diamond crystals are observed to be with integrated cubo-octahedral shape under optical microscope. Some etch pits were observed on {100} face of the most diamond crystals which are synthesized with sulfur-added Fe-Ni, while no etch pit in the diamond synthesized without sulfur additive. We also observed the etch pits under scanning electron microscope (SEM). In addition, we noticed that the content of inclusion in the diamond crystals synthesized with sulfur-added Fe-Ni is obviously lower than that in the diamond synthesized without additive.",
        "keywords": [
            "Etch pits",
            "Fe-Ni catalyst",
            "Inclusion",
            "Sulfur"
        ],
        "venue": "Jingangshi yu Moliao Moju Gongcheng/Diamond and Abrasives Engineering",
        "year": 2005,
        "id": "yL1vhcUb"
    },
    "b9mqVrK6": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Lab. of Superhard Materials"
            },
            {
                "name": "Ying Li",
                "org": "Henan University of Technology"
            },
            {
                "name": "Hongan Ma",
                "org": "Lab. of Superhard Materials"
            },
            {
                "name": "Yantao Li",
                "org": "Lab. of Superhard Materials"
            },
            {
                "name": "Chuanyi Zang",
                "org": "Henan University of Technology"
            },
            {
                "name": "Guozhong Ren",
                "org": "Lab. of Superhard Materials"
            },
            {
                "name": "Xiaopeng Jia",
                "org": "Henan University of Technology"
            }
        ],
        "title": "Analysis on synthesis of sulfur-doped diamond and impurity inclusions",
        "abstract": "Single-crystal diamonds were synthesized using respectively Ni",
        "keywords": [
            "Diamond",
            "Etch pits",
            "Inclusions",
            "Sulfur"
        ],
        "venue": "Jingangshi yu Moliao Moju Gongcheng/Diamond and Abrasives Engineering",
        "year": 2005,
        "id": "b9mqVrK6"
    },
    "BZytOsx6": {
        "authors": [
            {
                "name": "Yantao Li",
                "org": "Henan University of Technology"
            },
            {
                "name": "Xiaopeng Jia",
                "org": "Laboratory for Superhard Materials"
            },
            {
                "name": "Hongan Ma",
                "org": "Laboratory for Superhard Materials"
            },
            {
                "name": "Lin Zhou",
                "org": "Laboratory for Superhard Materials"
            }
        ],
        "title": "Effect of additive sulfur on diamond synthesized with catalyst powder Ni-Mn-Co by HPHT",
        "abstract": "The effect of sulfur on the diamond synthesized with catalyst powder Ni-Mn-Co under high temperature/high pressure was studied, and the mechanical performance of diamond was investigated. The result shows the nucleation of diamonds is disturbed obviously with a small amount of sulfur added into the capsules, which were pre-pressed by the mixture of catalyst powder Ni",
        "keywords": [
            "Additive sulfur",
            "Diamond",
            "HPHT",
            "Morphology",
            "Nucleation",
            "TI",
            "TTI"
        ],
        "venue": "Jingangshi yu Moliao Moju Gongcheng/Diamond and Abrasives Engineering",
        "year": 2005,
        "id": "BZytOsx6"
    },
    "OXZDbn2W": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Xiaopeng Jia",
                "org": ""
            },
            {
                "name": "Hongan Ma",
                "org": ""
            },
            {
                "name": "Lixue Chen",
                "org": ""
            },
            {
                "name": "Weili Guo",
                "org": ""
            },
            {
                "name": "Yantao Li",
                "org": ""
            }
        ],
        "title": "Influences of additive sulfur on the synthesis of industrial diamonds, using Ni70Mn25Co5 alloy powder as catalyst",
        "abstract": "Sulfur was introduced to the synthesis of industrial diamonds using Ni",
        "keywords": [
            "Additive sulfur",
            "Diamond",
            "MnS",
            "Ni70Mn25Co5 alloy powder"
        ],
        "venue": "Diamond and Related Materials",
        "year": 2006,
        "id": "OXZDbn2W"
    },
    "tTkicCLH": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Hefei University of Technology"
            },
            {
                "name": "Kemin Xue",
                "org": "Hefei University of Technology"
            },
            {
                "name": "Ping Li",
                "org": "Hefei University of Technology"
            }
        ],
        "title": "Study on hydroforming process of automobile front transom based on FEM",
        "abstract": "To achieve weight reduction, strength increase and stiffness improvement, tube hydro-forming is widely used in auto industry. The hydroforming process of automobile front transom was simulated by FEM, which is based on elastic-plastic finite element method and BT shell element theory. The effect of forming process parameters, such as internal pressure loading path and initial tube size, were simulated and discussed. The simulation results indicated that suitable initial tube size and loading path can obviously improve the distribution of the thickness and forming limit of the tube. And for the front transom, tube size \u03c655 mm and bilinear loading path are the best process parameters.",
        "keywords": [
            "Forming process",
            "Hydroforming",
            "Numerical simulation",
            "Tube"
        ],
        "venue": "Zhongguo Jixie Gongcheng/China Mechanical Engineering",
        "year": 2006,
        "id": "tTkicCLH"
    },
    "acQKJy1f": {
        "authors": [
            {
                "name": "Youjin Zheng",
                "org": "Mudanjiang Teachers' College"
            },
            {
                "name": "Hongan Ma",
                "org": "National Lab. of Superhard Materials"
            },
            {
                "name": "Lin Zhou",
                "org": "National Lab. of Superhard Materials"
            },
            {
                "name": "Jieming Qin",
                "org": "National Lab. of Superhard Materials"
            },
            {
                "name": "Chuanyi Zang",
                "org": "National Lab. of Superhard Materials"
            },
            {
                "name": "Xiaopeng Jia",
                "org": "Henan Polytechnic University"
            }
        ],
        "title": "Nucleation properties of diamond in FeNi-Si-C system",
        "abstract": "In this article, diamond single crystal synthetic experiments were carried out in cubic press using Silicon-contained FeNi powder as catalyst. The nucleation properties of diamond in FeNi-Si-C system under HPHT were researched. The result indicates that, the minimum growth conditions, pressure and temperature, for diamond formation have not changed with the content of silicon. However, the amount of nucleation has a tendency to increase with the increasing of silicon content. Using optical microscope, we find that the color and morphology of the synthetic diamond crystal from FeNi-Si-C system have greater differences to that from FeNi-C system. The phenomenon of Polarization has appeared. That is to say, some crystals are of high quality, while the rest are of poor quality, they are light black and incomplete. And the rate of poor quality crystal tends to increase with the increase of Si content in synthesis system. X-ray diffractions of the synthesis bars, which were obtained under different conditions, show that FeSi and Fe",
        "keywords": [
            "Diamond",
            "Heteromorphy nuclear",
            "Powder catalyst",
            "Silicon",
            "The amount of nucleation"
        ],
        "venue": "Jingangshi yu Moliao Moju Gongcheng/Diamond and Abrasives Engineering",
        "year": 2006,
        "id": "acQKJy1f"
    },
    "86cajfdK": {
        "authors": [
            {
                "name": "Ke-Min Xue",
                "org": "School of Materials Science and Engineering"
            },
            {
                "name": "Jie Jin",
                "org": "School of Materials Science and Engineering"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Materials Science and Engineering"
            },
            {
                "name": "Wan-Bin Wu",
                "org": "38th Research Institute"
            }
        ],
        "title": "Optimization of H-bend wave-guide blank based on numerical simulation",
        "abstract": "The numerical simulation is used in the optimize process of H-bend wave-guide blank, the influence of FLD, the distribution of thickness, the thinning rate and spring back which is worked in the deep drawing process of different kinds of blanks is researched. The numerical simulation results of the deep drawing process of the blank which is gotten by the Blank Size Engineering (BSE) and the one which is gotten by the expansion of die off-set are contrasted and analyzed, and then the modification project is put forward to get the more reasonable blank. The results shows that: The shaped effect is influenced by the shape of blank very much. The fifth blank which has a 90 angle is the best one, because its extent of spring back and cracking is least. Then a drawing experiment is done to approve the result of simulation. A general good agreement is found between them throughout the study, and simulation can be used to instruct productions.",
        "keywords": [
            "Deep drawing",
            "Numerical simulation",
            "Springback",
            "The optimization of blank"
        ],
        "venue": "Suxing Gongcheng Xuebao/Journal of Plasticity Engineering",
        "year": 2007,
        "id": "86cajfdK"
    },
    "Fc6VP3aT": {
        "authors": [
            {
                "name": "Qigang Han",
                "org": "National Laboratory of Superhard Materials"
            },
            {
                "name": "Hongan Ma",
                "org": "National Laboratory of Superhard Materials"
            },
            {
                "name": "Rui Li",
                "org": "National Laboratory of Superhard Materials"
            },
            {
                "name": "Lin Zhou",
                "org": "National Laboratory of Superhard Materials"
            },
            {
                "name": "Yu Tian",
                "org": "National Laboratory of Superhard Materials"
            },
            {
                "name": "Zhongzhu Liang",
                "org": "National Laboratory of Superhard Materials"
            },
            {
                "name": "Xiaopeng Jia",
                "org": "National Laboratory of Superhard Materials"
            }
        ],
        "title": "Finite element analysis of high-pressure anvils according to the principle of lateral support",
        "keywords": [
            ""
        ],
        "venue": "Journal of Applied Physics",
        "year": 2007,
        "id": "Fc6VP3aT"
    },
    "Mqu990YR": {
        "authors": [
            {
                "name": "Qigang Han",
                "org": "National Laboratory of Superhard Materials"
            },
            {
                "name": "Hongan Ma",
                "org": "National Laboratory of Superhard Materials"
            },
            {
                "name": "Lin Zhou",
                "org": "National Laboratory of Superhard Materials"
            },
            {
                "name": "Cong Zhang",
                "org": "National Laboratory of Superhard Materials"
            },
            {
                "name": "Yu Tian",
                "org": "National Laboratory of Superhard Materials"
            },
            {
                "name": "Xiaopeng Jia",
                "org": "National Laboratory of Superhard Materials"
            },
            {
                "name": "Rui Li",
                "org": "School of Materials Science and Engineering"
            }
        ],
        "title": "Finite element design of double bevel anvils of large volume cubic high pressure apparatus",
        "keywords": [
            ""
        ],
        "venue": "Review of Scientific Instruments",
        "year": 2007,
        "id": "Mqu990YR"
    },
    "s4uRapQp": {
        "authors": [
            {
                "name": "Tai-Chao Su",
                "org": "National Lab. of Superhard Materials"
            },
            {
                "name": "Hong-An Ma",
                "org": "National Lab. of Superhard Materials"
            },
            {
                "name": "Pin-Wen Zhu",
                "org": "National Lab. of Superhard Materials"
            },
            {
                "name": "Lin Zhou",
                "org": "National Lab. of Superhard Materials"
            },
            {
                "name": "Jian-Gang Guo",
                "org": "National Lab. of Superhard Materials"
            },
            {
                "name": "Xiao-Peng Jia",
                "org": "Institute of Materials Science and Technology"
            }
        ],
        "title": "Study of the thermoelectric properties of PbTe doped with Bi2Te3 at high-pressure and high-temperature",
        "abstract": "N-type lead telluride compounds (PbTe) doped with Bi",
        "keywords": [
            "Bi2Te3",
            "Doping",
            "High energy physics",
            "High-pressure and high-temperature",
            "PbTe",
            "Thermoelectric materials"
        ],
        "venue": "Jilin Daxue Xuebao (Gongxueban)/Journal of Jilin University (Engineering and Technology Edition)",
        "year": 2008,
        "id": "s4uRapQp"
    },
    "7wUPofuN": {
        "authors": [
            {
                "name": "Taichao Su",
                "org": ""
            },
            {
                "name": "Xiaopeng Jia",
                "org": ""
            },
            {
                "name": "Hongan Ma",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Jiangang Guo",
                "org": ""
            },
            {
                "name": "Nan Dong",
                "org": ""
            }
        ],
        "title": "Enhanced power factor of Ag0.208Sb0.275Te0.517 prepared by HPHT",
        "abstract": "In this Letter, p-type thermoelectric materials Ag",
        "keywords": [
            "Ag0.208Sb0.275Te0.517",
            "HPHT",
            "Power factor"
        ],
        "venue": "Physics Letters, Section A: General, Atomic and Solid State Physics",
        "year": 2008,
        "id": "7wUPofuN"
    },
    "boAvqTt1": {
        "authors": [
            {
                "name": "You-Jin Zheng",
                "org": ""
            },
            {
                "name": "Hong-An Ma",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Jie-Ming Qin",
                "org": ""
            },
            {
                "name": "Xiao-Peng Jia",
                "org": ""
            }
        ],
        "title": "Study on inclusion in diamond synthesized using FeNi as catalyst",
        "abstract": "Diamond single crystals with cubic, cubo-octahedral and octahedral shape were synthesized from FeNi-C system. The crystals were integrated and there were little inclusions in them. It is found that the inclusions in cubic and octahedral diamonds radiated from crystal core to tip areas. However, the phenomenon didnt appear on cubo-octahedral diamond. This could attribute to the difference of growth rates along different crystal orientation of diamond. When a higher growth rate was get on certain crystal orientation of diamond, some impurity elements can not be absolutely expelled in time. During the quenching process, inclusions come into being. The results of M\u00f6ssbauer spectrum indicated that there were Fe",
        "keywords": [
            "Diamond",
            "Growth rate",
            "Inclusions",
            "Radiating"
        ],
        "venue": "Rengong Jingti Xuebao/Journal of Synthetic Crystals",
        "year": 2008,
        "id": "boAvqTt1"
    },
    "ZKY7OEKl": {
        "authors": [
            {
                "name": "Yafei Zhang",
                "org": "National Lab of Superhard Materials"
            },
            {
                "name": "Chuanyi Zang",
                "org": "Henan Polytechnic University"
            },
            {
                "name": "Hongan Ma",
                "org": "National Lab of Superhard Materials"
            },
            {
                "name": "Zhongzhu Liang",
                "org": "State Key Laboratory of Applied Optics"
            },
            {
                "name": "Lin Zhou",
                "org": "National Lab of Superhard Materials"
            },
            {
                "name": "Shangsheng Li",
                "org": "National Lab of Superhard Materials"
            },
            {
                "name": "Xiaopeng Jia",
                "org": "Henan Polytechnic University"
            }
        ],
        "title": "HPHT synthesis of large single crystal diamond doped with high nitrogen concentration",
        "abstract": "Large green single crystal diamond with high nitrogen concentration is firstly synthesized by temperature gradient method under high pressure and high temperature (HPHT). Sodium azide (NaN",
        "keywords": [
            "High nitrogen concentration",
            "HPHT",
            "Single crystal diamond",
            "Synthesis"
        ],
        "venue": "Diamond and Related Materials",
        "year": 2008,
        "id": "ZKY7OEKl"
    },
    "qFcJhxby": {
        "authors": [
            {
                "name": "Taichao Su",
                "org": ""
            },
            {
                "name": "Xiaopeng Jia",
                "org": ""
            },
            {
                "name": "Hongan Ma",
                "org": ""
            },
            {
                "name": "Chuanyi Zang",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Jiangang Guo",
                "org": ""
            },
            {
                "name": "Nan Dong",
                "org": ""
            }
        ],
        "title": "HPHT synthesis and electrical properties of AgSbTe2-Ag2Te thermoelectric alloys",
        "abstract": "In this letter, p-type pseudo-binary AgSbTe",
        "keywords": [
            "Ag2Te",
            "AgSbTe2",
            "Electrical properties",
            "HPHT",
            "X-ray techniques"
        ],
        "venue": "Materials Letters",
        "year": 2008,
        "id": "qFcJhxby"
    },
    "wfeA2oMD": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "School of Mechanical Engineering"
            },
            {
                "name": "Xiao-Min Cheng",
                "org": "School of Mechanical Engineering"
            },
            {
                "name": "Ke-Min Xue",
                "org": "School of Materials Science and Engineering"
            },
            {
                "name": "Ping Li",
                "org": "School of Materials Science and Engineering"
            },
            {
                "name": "Wen-Jiang Yang",
                "org": "Institute of Automobile Technology"
            },
            {
                "name": "Li-Chun Cui",
                "org": "Institute of Automobile Technology"
            }
        ],
        "title": "Investigation of forming stress limit in tube hydroforming of automobile framework",
        "abstract": "The forming limit stress diagram (FLSD) which established with limit stress is independent on the strain paths and it is practical to use as the criterion of forming limit under complex strain paths. The forming limit of 3A21 Aluminum alloy sheet was tested and the forming limit diagram (FLD) was determined. Then the FLSD of 3A21 was constituted by transformation formulas between limit strain and limit stress. This FLSD was used in conjunction with LS-DYNA finite element simulation to predict the onset of fracture and limit forming pressure in tube hydroforming. The simulation result compares well with the experimental result. The FLSD is able to predict the forming limit of tube hydroforming with remarkable accuracy.",
        "keywords": [
            "Forming limit stress diagram",
            "Fracture",
            "Hydroforming",
            "Numerical simulation"
        ],
        "venue": "Suxing Gongcheng Xuebao/Journal of Plasticity Engineering",
        "year": 2008,
        "id": "wfeA2oMD"
    },
    "LXWkb1R3": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Department of Physics"
            },
            {
                "name": "Xiao-Peng Jia",
                "org": "Henan Polytechnic University"
            },
            {
                "name": "Hong-An Ma",
                "org": "Henan Polytechnic University"
            },
            {
                "name": "You-Jin Zheng",
                "org": "National Laboratory of Superhard Materials"
            },
            {
                "name": "Yan-Tao Li",
                "org": "National Laboratory of Superhard Materials"
            }
        ],
        "title": "Synthesis of industrial diamonds using FeNi alloy powder as catalyst",
        "abstract": "Synthesis of diamond single crystals in Fe",
        "keywords": [
            "Diamond",
            "Fe80Ni20",
            "Inclusion",
            "Morphology"
        ],
        "venue": "Chinese Physics B",
        "year": 2008,
        "id": "LXWkb1R3"
    },
    "kkNOprjC": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Physics Department"
            },
            {
                "name": "Xiao-Peng Jia",
                "org": "Henan Polytechnic University"
            },
            {
                "name": "Hong-An Ma",
                "org": "Henan Polytechnic University"
            },
            {
                "name": "You-Jin Zheng",
                "org": "National Laboratory of Superhard Materials"
            },
            {
                "name": "Yan-Tao Li",
                "org": "National Laboratory of Superhard Materials"
            }
        ],
        "title": "Industrial diamonds grown in Ni70Mn25Co 5-graphite-sulfur system under HPHT",
        "abstract": "This paper reports that diamond single crystals were synthesized from sulfur-added Ni",
        "keywords": [
            "Diamond",
            "MnS",
            "Morphology",
            "Sulfur"
        ],
        "venue": "Chinese Physics B",
        "year": 2009,
        "id": "kkNOprjC"
    },
    "aolesWu7": {
        "authors": [
            {
                "name": "Yong Tang",
                "org": "School of Materials Science and Engineering"
            },
            {
                "name": "Ke-Min Xue",
                "org": "School of Materials Science and Engineering"
            },
            {
                "name": "Ping Li",
                "org": "School of Materials Science and Engineering"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Materials Science and Engineering"
            },
            {
                "name": "Hua Du",
                "org": "School of Materials Science and Engineering"
            }
        ],
        "title": "A simulation study on the multi-step hydroforming process for automotive front transom",
        "abstract": "Taking an automobile front transom as a typical example, a rotary bending and a die bending multi-step numerical simulation of hydroforming were investigated, by using a dynamic explicit FEM code, eta/DYNAFORM. The forming limit diagrams of the hydroformed automobile front transom of each procedure were presented and the forming qualities were analyzed. On basis of this, experiments of tube rotary bending and hydroforming were carried out. The thickness distribution of typical section was measured and compared with the simulation result. It shows that the simulation result agrees well with the experimental result. The thickness distribution of bending influences that of hydroforming. Multi-step numerical simulation can enhance simulation precision of hydroforming. The thickness distribution of tube die bending which can help improve hydroforming quality of automobile front transom is better than the result of tube rotary bending.",
        "keywords": [
            "FEM",
            "Hydroforming",
            "Numerical simulation",
            "Pre-forming",
            "Tube bending"
        ],
        "venue": "Suxing Gongcheng Xuebao/Journal of Plasticity Engineering",
        "year": 2009,
        "id": "aolesWu7"
    },
    "pM35ip0Y": {
        "authors": [
            {
                "name": "Kemin Xue",
                "org": "School of Materials Science and Engineering"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Materials Science and Engineering"
            },
            {
                "name": "Ping Li",
                "org": "School of Materials Science and Engineering"
            }
        ],
        "title": "Prediction of defects in tube hydroforming based on forming stress limit",
        "abstract": "Transformation relation between limit strain and limit stress is derived on the basis of the plastic theory and Hill79 yield criterion. Then, the conventional strain-based forming limit diagram (FLD) of 2008T4 Aluminum alloy sheet is converted into stress-based forming limit stress diagram (FLSD). This FLSD is used in conjunction with LS-DYNA finite element simulation to predict the onset of necking and the limit pressure in T-shaped tube hydroforming. The prediction results using FLSD and FLD are also compared. The research indicates that two predicted forming limits are obviously different. Although the necking occurs at the same location in both prediction results, the limit pressures make a great difference. And the limit pressure predicted by FLSD compares well with the experimental result. In view of the strong path-dependence of the FLD, it will be more convenient and reliable to use FLSD criterion in tube hydroforming analysis.",
        "keywords": [
            "Forming limit diagram",
            "Forming limit stress diagram",
            "Hydroforming",
            "Numerical simulation"
        ],
        "venue": "Jixie Gongcheng Xuebao/Journal of Mechanical Engineering",
        "year": 2009,
        "id": "pM35ip0Y"
    },
    "LfI8EARB": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "School of Mechanica Engineering"
            },
            {
                "name": "Xiaomin Cheng",
                "org": "School of Mechanica Engineering"
            }
        ],
        "title": "Loading path design for tube hydroforming based on fuzzy logical control and CAE method",
        "abstract": "In order to overcome the disadvantages of conventional optimization methods, a real-time feedback optimization method combined with fuzzy logical control and adaptive numerical simulation was proposed. Using fuzzy logical controller and defect control rules, development trend of forming defect was discovered and fed back to simulation software program in real time during the numerical simulation process, then the process parameters were adjusted to avoid occurrence of forming defect, the optimized forming loading path was obtained ultimately. Study results indicated that the hydroforming quality of T-shaped tube was improved under fuzzy logical control optimized loading path, fuzzy logical controlled optimization achieved prospective objective, and the optimization process can lead to better forming quality. \u00a92009 IEEE.",
        "keywords": [
            "Fuzzy logical control",
            "Loading path",
            "Optimization",
            "Tube hydroforming"
        ],
        "venue": "Proceeding 2009 IEEE 10th International Conference on Computer-Aided Industrial Design and Conceptual Design: E-Business, Creative Design, Manufacturing - CAID and CD'2009",
        "year": 2009,
        "id": "LfI8EARB"
    },
    "dSchPslT": {
        "authors": [
            {
                "name": "Xiaomin Cheng",
                "org": "School of Mechanical Engineering, Ningbo University of Technology"
            },
            {
                "name": "Ye Xu",
                "org": "School of Mechanical Engineering, Ningbo University of Technology"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Mechanical Engineering, Ningbo University of Technology"
            },
            {
                "name": "Guoliang Zhang",
                "org": "School of Mechanical Engineering, Ningbo University of Technology"
            },
            {
                "name": "Naiyu Shen",
                "org": "School of Mechanical Engineering, Ningbo University of Technology"
            }
        ],
        "title": "RETRACTED ARTICLE: Water tweezers for pariticles gagging",
        "abstract": "In recent years, the microfabrication has grown rapidly, and one of the key technique and important basis is paritiele trapping and manipulation. Now, it develops mostly on light, electricity and plasma to make it. The text raises a fire-new concept of \"water tweezers\": when fistulous micro water-jet acts on the face of paritiele, the block of viscosity that causes a change of flow velocity and pressure distribution of fluid microaggregate in boundary layer, will make an abruption on the face of fluid microaggregate and paritiele somewhere, then reverse flow following it, ultimately forms symmetrical karman vortex. The face tension of liquid level, the support force of karman vortex and circumferential flow lift act together on paritiele and give birth to gagging to it, that forming \"water tweezers\" finally. Based on the theory analysis to \"water tweezers\", by adopting singularity method, the establishment of stream function and velocity potential model of water-jet provides basis for the trapping to partiriele by using \"water tweezers\". \u00a9 2010 IEEE.",
        "keywords": [
            "Pariticle",
            "Trapping",
            "Water tweezers"
        ],
        "venue": "ICCASM 2010 - 2010 International Conference on Computer Application and System Modeling, Proceedings",
        "year": 2010,
        "id": "dSchPslT"
    },
    "m5Q4PC6f": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "School of Mechanical Engineering"
            },
            {
                "name": "Xiaomin Cheng",
                "org": "School of Mechanical Engineering"
            }
        ],
        "title": "Study on product design and process simulation of hydroformed automobile framework",
        "abstract": "To achieve smaller weight, stronger strength and higher stiffness, tube hydroforming is widely used in the industry. The front beam is analysed the front beam part is redesigned based on the technics, and automotive structural lightweight and integration are achieved under the precondition of ensuring vehicle performance and security. Then, the hydroforming process of front beam is analyzed by numerical simulation based upon the elastic-plastic finite element method, Belytschko-Tsay shell element theory and dynamic explicit solution, the internal pressure loading path as the main hydroforming process parameters is discussed in detail. The present analysis provide basis for its applications. \u00a9 (2010) Trans Tech Publications.",
        "keywords": [
            "Forming process",
            "Hydroforming",
            "Numerical simulation",
            "Product design"
        ],
        "venue": "Advanced Materials Research",
        "year": 2010,
        "id": "m5Q4PC6f"
    },
    "0x6QTt6c": {
        "authors": [
            {
                "name": "XiaoMin Cheng",
                "org": "School of Mechanical Engineering"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Mechanical Engineering"
            },
            {
                "name": "Rufu Hu",
                "org": "School of Mechanical Engineering"
            },
            {
                "name": "Zaohui Cheng",
                "org": "School of Mechanical Engineering"
            },
            {
                "name": "Yueding Wu",
                "org": "Ningbo Yuli Machinery Manufacturing Co., Ltd."
            }
        ],
        "title": "Simulation for water jet incremental sheet metal forming",
        "abstract": "Water jet incremental sheet metal forming is a new method of sheet metal forming. Based on the feature of forming, simulation model is established, mesh generation is carved up, boundary condition and constraint are set, deformation degree is calculated, and after deformation degree and stress analysis an experiment of water jet incremental sheet metal forming is done. By giving a test to forming result, it can be known that the error between simulation result and experiment result is on the small side. It shows that the choice of model, initial parameters, boundary condition, constraint, and so on, in the simulation is basically reasonable, so a reference to that will be usefully for other parts simulation before processing. \u00a9 2010 IEEE.",
        "keywords": [
            "Incremental forming",
            "Sheet metal",
            "Simulation",
            "Water jet"
        ],
        "venue": "ICCMS 2010 - 2010 International Conference on Computer Modeling and Simulation",
        "year": 2010,
        "id": "0x6QTt6c"
    },
    "bIJ9DXmr": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "School of Physical Science and Technology"
            },
            {
                "name": "Hong-An Ma",
                "org": "State Key Laboratory of Superhard Materials"
            },
            {
                "name": "Pu-Nan Sun",
                "org": "School of Physical Science and Technology"
            },
            {
                "name": "Xiao-Peng Jia",
                "org": "State Key Laboratory of Superhard Materials"
            }
        ],
        "title": "Study on sulfur-doped diamond single crystal in NiMnCo-C-S system",
        "abstract": "Diamond single crystals were synthesized in Ni",
        "keywords": [
            "Adjunct crystal",
            "Composition stoichiometry",
            "Diamond",
            "Sulfur doped"
        ],
        "venue": "Rengong Jingti Xuebao/Journal of Synthetic Crystals",
        "year": 2011,
        "id": "bIJ9DXmr"
    },
    "r0Ik4MhA": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Xiao Min Cheng",
                "org": ""
            }
        ],
        "title": "Artificial intelligence optimization and experimental study of auto panel stamping process",
        "abstract": "Auto panel stamping is a complicated plastic deformation process with geometry nonlinear, material nonlinearity and numerous process parameters. The stamping process of a typical auto panel wheel wrap was studied by artificial intelligent optimization and physical experiment. The prediction model of object function was established using artificial neural network. In object function, blank-holder force, drawbead height and fillet radius were selected as the optimized variables and prevention of rupture was considered as the optimization objective. Process parameters optimization was performed with genetic algorithm. The optimized process parameters were used to guide die design and testing, and the result of wheel wrap stamping showed that the forming quality was obviously improved. So the process optimization based on artificial neural network and genetic algorithm is feasible and efficient for auto panel stamping. \u00a9 (2011) Trans Tech Publications.",
        "keywords": [
            "Artificial intelligence",
            "Auto panel",
            "Process optimization",
            "Stamping"
        ],
        "venue": "Applied Mechanics and Materials",
        "year": 2011,
        "id": "r0Ik4MhA"
    },
    "Pk0OQ1bV": {
        "authors": [
            {
                "name": "Xiaomin Cheng",
                "org": "Ningbo University of Technology"
            },
            {
                "name": "Lin Zhou",
                "org": "Ningbo University of Technology"
            },
            {
                "name": "Liang Wang",
                "org": "Ningbo University of Technology"
            },
            {
                "name": "Gen Zhou",
                "org": "Ningbo University of Technology"
            }
        ],
        "title": "The experiment study of water jet incremental sheet metal forming",
        "abstract": "For the manufacture of panel parts, incremental sheet metal forming is significant in reality. This study put forward a method of incremental sheet metal forming: High-handed water jet with constant pressure and speed that caused by high pressure system acts on sheet metal and makes it out of shape, following transmutation superposition the requisite parts can be made. Based on this theory, a system of incremental sheet metal forming by using water jet is designed. At the same time, a forming experiment device is developed which is used to test the influence of water jet pressure, sheet metal thick, target distance to forming result. Finally, the optimized technological parameters of forming will be obtained. Within the work range, the higher pressure of water jet is, the more obvious forming result will be, and a great target distance will make forming result worse, besides sheet metal thick can make a difference of it. If sheet metal thick is invariable, there is interaction among pressure, target distance and feed velocity, so they influence forming result together. \u00a9 2011 Trans Tech Publications, Switzerland.",
        "keywords": [
            "Forming experiment",
            "Incremental forming",
            "Sheet metal forming",
            "Water jet"
        ],
        "venue": "Advanced Materials Research",
        "year": 2011,
        "id": "Pk0OQ1bV"
    },
    "JwdPlSYS": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "School of Mechanical Engineering"
            },
            {
                "name": "Xiaomin Cheng",
                "org": "School of Mechanical Engineering"
            }
        ],
        "title": "Prediction of T-shaped tube hydroforming stress limit",
        "abstract": "Tube hydroforming has been widely used in auto industry due to its remarkable advantages compared with conventional manufacturing via stamping and welding. The forming limit stress diagram (FLSD) which is independent of strain paths is of great significance to tube hydroforming. The FLSD of 2008T4 tube blank was established to predict fracture defect in T-shaped tube hydroforming simulation. By numerical simulation method, the stress limit and strain limit were analyzed and fracture defects were predicted. Two prediction results of the fracture defects location were the same yet the limit pressure values corresponding to fracture were different. The FLSD prediction result was close to the experiment result, so the accuracy of FLSD as tube hydroforming limit criterion was proved. \u00a9 (2011) Trans Tech Publications, Switzerland.",
        "keywords": [
            "Forming stress limit",
            "Fracture",
            "Hydroforming",
            "T-shaped tube"
        ],
        "venue": "Key Engineering Materials",
        "year": 2011,
        "id": "JwdPlSYS"
    },
    "SKHLhdw0": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Department of Physics"
            },
            {
                "name": "Punan Sun",
                "org": "Department of Physics"
            },
            {
                "name": "Hongan Ma",
                "org": "National Laboratory of Superhard Materials"
            },
            {
                "name": "Xiaopeng Jia",
                "org": "National Laboratory of Superhard Materials"
            }
        ],
        "title": "Synthesis of diamond skigle crystals in Fe-C-S systen by high temperature and high pressure",
        "abstract": "By adding sulfur as additive in Fe-C system, diamond single crystals was synthesized under high temperature and high pressure(HTHP) condition. It was indicated that the sulfur had reacted with iron under HTHP. This influenced the catalytic performance of iron and then inhibited the spontaneous nucleation of diamond to a certain degree. The Introduction of sulfur could widen the growth temperature range of cubo-octahedral diamond crystal and increase its production controliability. Observation under optical microscope revealed that diamonds synthesized with Fe-O-S had dark yellow surface appearance, quite perfect shape and with little inclusions. SEM results showed that the plane(111) of cubo-octahedral diamond was smooth, while the plane(100), covered with a lot of \"small hilbcks\" and usualy having a larger concave in them mildle, was quite rough. \u00a9 1994-2011 China Academic Journal Electronic Publishing House. All rights reserved.",
        "keywords": [
            "Diamond",
            "High temperature and high pressure method",
            "Sulfur additive"
        ],
        "venue": "Jingangshi yu Moliao Moju Gongcheng/Diamond and Abrasives Engineering",
        "year": 2011,
        "id": "SKHLhdw0"
    },
    "VATAhZby": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "School of Mechanical Engineering"
            },
            {
                "name": "Jinfu Xu",
                "org": "Institute of Materials Engineering"
            },
            {
                "name": "Xuebo Xu",
                "org": "Institute of Materials Engineering"
            }
        ],
        "title": "Construction of scientific evaluation system for energy saving and emission reduction oriented to product full life-cycle",
        "abstract": "The widely used single assessment index such as energy consumption and main pollutants total emissions index can't comprehensively evaluation energy conservation and emission reduction. In this paper, a scientific comprehensive evaluation method of energy consumption based on the product life-cycle was proposed. This method fully consider industry characteristics at the same time, comprehensively use stratified fuzzy evaluation method. And the multi-objective colligation evaluation model and scientific evaluation system for energy saving and emission reduction oriented to industry characteristics was constructed. Finally, the empirical research was carried out take the heat treatment industry in Ningbo city as an example, and the result shows that this evaluation system is scientific and reasonable. \u00a9 (2013) Trans Tech Publications, Switzerland.",
        "keywords": [
            "Energy saving and emission reduction",
            "Heat treatment industry",
            "Product full life-cycle"
        ],
        "venue": "Applied Mechanics and Materials",
        "year": 2013,
        "id": "VATAhZby"
    },
    "Kz1dqdFj": {
        "authors": [
            {
                "name": "Jingwan Kang",
                "org": "Department of Chemistry"
            },
            {
                "name": "Haixia Wu",
                "org": "Department of Chemistry"
            },
            {
                "name": "Xiaoquan Lu",
                "org": "Department of Chemistry"
            },
            {
                "name": "Yongsheng Wang",
                "org": "Department of Chemistry"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Chemistry"
            }
        ],
        "title": "Study on the interaction of new water-soluble porphyrin with DNA",
        "abstract": "A porphyrin meso-tetrakis{[4-(1-pyridyl)propoxy]phenyl}porphyrin (TPyPP) and its Ni complex (TPyPP(Ni)) have been synthesized and characterized by ",
        "keywords": [
            "DNA",
            "Out-binding",
            "Water-soluble porphyrin"
        ],
        "venue": "Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy",
        "year": 2005,
        "id": "Kz1dqdFj"
    },
    "fN88wO58": {
        "authors": [
            {
                "name": "Xiao-Feng Zhu",
                "org": "State Key Laboratory of Modern Acoustics"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Modern Acoustics"
            },
            {
                "name": "Dong Zhang",
                "org": "State Key Laboratory of Modern Acoustics"
            },
            {
                "name": "Xiu-Fen Gong",
                "org": "State Key Laboratory of Modern Acoustics"
            }
        ],
        "title": "Nonlinear propagation of focused ultrasound in layered biological tissues based on angular spectrum approach",
        "abstract": "Nonlinear propagation of focused ultrasound in layered biological tissues is theoretically studied by using the angular spectrum approach (ASA), in which an acoustic wave is decomposed into its angular spectrum and the distribution of nonlinear acoustic fields is calculated in arbitrary planes normal to the acoustic axis. Several biological tissues are used as specimens inserted into the focusing region illuminated by a focused piston source. The second harmonic components within or beyond the biological specimens are numerically calculated. Validity of the theoretical model is examined by measurements. This approach employing the fast Fourier transformation gives a clear visualization of the focused ultrasound, which is helpful for nonlinear ultrasonic imaging. \u00a9 2005 Chin. Phys. Soc. and IOP Publishing Ltd.",
        "keywords": [
            "Angular spectrum approach",
            "Focused ultrasound",
            "Second harmonic imaging"
        ],
        "venue": "Chinese Physics",
        "year": 2005,
        "id": "fN88wO58"
    },
    "lG7xyaPo": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Xiao-Qiang Yu",
                "org": ""
            },
            {
                "name": "Yong-Yuan Zhu",
                "org": ""
            }
        ],
        "title": "Propagation and dual-localization of surface plasmon polaritons in a quasiperiodic metal heterowaveguide",
        "abstract": "Based on the transfer matrix method and the finite-difference time-domain analysis, we investigate the propagation and scattering of surface plasmon polaritons (SPPs) in a quasiperiodic metal heterowaveguide. By selecting appropriate thickness of the defect layer, the two SPP modes can be adjusted to localize at around 1310 and 1550 nm simultaneously. The numerical results reveal that the realization of miniaturized photonic devices is feasible at the two important telecommunicate wavelengths. The structure can be applied to the double-band plasmon Bragg reflector, double-channel light emitters and filters. \u00a9 2006 American Institute of Physics.",
        "keywords": [
            ""
        ],
        "venue": "Applied Physics Letters",
        "year": 2006,
        "id": "lG7xyaPo"
    },
    "r42SUVan": {
        "authors": [
            {
                "name": "Dong Zhang",
                "org": "Institute of Acoustics"
            },
            {
                "name": "Lin Zhou",
                "org": "Institute of Acoustics"
            },
            {
                "name": "Li-Sheng Si",
                "org": "Institute of Acoustics"
            },
            {
                "name": "Xiu-Fen Gong",
                "org": "Institute of Acoustics"
            }
        ],
        "title": "A simple model for nonlinear confocal ultrasonic beams",
        "abstract": "A confocally and coaxially arranged pair of focused transmitter and receiver represents one of the best geometries for medical ultrasonic imaging and non-invasive detection. We develop a simple theoretical model for describing the nonlinear propagation of a confocal ultrasonic beam in biological tissues. On the basis of the parabolic approximation and quasi-linear approximation, the nonlinear Khokhlov-Zabolotskaya-Kuznetsov (KZK) equation is solved by using the angular spectrum approach. Gaussian superposition technique is applied to simplify the solution, and an analytical solution for the second harmonics in the confocal ultrasonic beam is presented. Measurements are performed to examine the validity of the theoretical model. This model provides a preliminary model for acoustic nonlinear microscopy. \u00a92007 Chinese Physical Soceity and IOP Publishing Ltd.",
        "keywords": [
            ""
        ],
        "venue": "Chinese Physics Letters",
        "year": 2007,
        "id": "r42SUVan"
    },
    "AvuxJbNv": {
        "authors": [
            {
                "name": "Xiao-Qiang Yu",
                "org": "National Laboratory of Solid State Microstructures"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Physics"
            },
            {
                "name": "Yong-Yuan Zhu",
                "org": "National Laboratory of Solid State Microstructures"
            },
            {
                "name": "Shi-Ning Zhu",
                "org": "National Laboratory of Solid State Microstructures"
            }
        ],
        "title": "Plasmon-assisted phase-matched second- and third-harmonic generation in single-negative heterostructures",
        "abstract": "Dispersion relations of surface plasmon polaritons (SPPs) in sandwiched optical systems are studied. The system is actually a kind of SPP waveguides, with two kinds of single negative material (SNG) as core and cladding layers, respectively. Since both TM and TE polarized SPPs can be excited in the structure, the dispersion of SPPs becomes more abundant and leads to colorful nonlinear optical properties. The authors demonstrate the effective phase-matched second and third-harmonic generation (SHG, THG) assisted by the coupled SPPs. A cascaded second-order nonlinear process can also be achieved in the structure when the thickness of the core layer is properly selected, leading to the simultaneous SHG and THG. Further investigations show that much easier phase-matching can be fulfilled in the SNG waveguide array. Our results would be of potential use for surface-enhanced frequency conversion device such as light emitters or lasers. \u00a9 2008 Chinese Physical Society and IOP Publishing Ltd.",
        "keywords": [
            ""
        ],
        "venue": "Chinese Physics Letters",
        "year": 2008,
        "id": "AvuxJbNv"
    },
    "4qMWm2Rl": {
        "authors": [
            {
                "name": "Tao Yin",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Min Zhi Rong",
                "org": ""
            },
            {
                "name": "Ming Qiu Zhang",
                "org": ""
            }
        ],
        "title": "Self-healing woven glass fabric/epoxy composites with the healant consisting of micro-encapsulated epoxy and latent curing agent",
        "abstract": "This paper reports a study of self-healing woven glass fabric reinforced epoxy composites. The healing agent was a two-component one synthesized in the authors' laboratory, which consisted of epoxy-loaded urea-formaldehyde microcapsules as the polymerizable binder and CuBr",
        "keywords": [
            ""
        ],
        "venue": "Smart Materials and Structures",
        "year": 2008,
        "id": "4qMWm2Rl"
    },
    "Me3n42u5": {
        "authors": [
            {
                "name": "Jiahong Zhou",
                "org": "Jiangsu Engineering Research Center for Bio-medial Function Materials"
            },
            {
                "name": "Lin Zhou",
                "org": "Jiangsu Engineering Research Center for Bio-medial Function Materials"
            },
            {
                "name": "Chao Dong",
                "org": "Jiangsu Engineering Research Center for Bio-medial Function Materials"
            },
            {
                "name": "Yuying Feng",
                "org": "Jiangsu Engineering Research Center for Bio-medial Function Materials"
            },
            {
                "name": "Shaohua Wei",
                "org": "Jiangsu Engineering Research Center for Bio-medial Function Materials"
            },
            {
                "name": "Jian Shen",
                "org": "Jiangsu Engineering Research Center for Bio-medial Function Materials"
            },
            {
                "name": "Xuesong Wang",
                "org": "Technocal Institute of Physics and Chemistry"
            }
        ],
        "title": "Preparation and photodynamic properties of water-soluble hypocrellin A-silica nanospheres",
        "abstract": "Water-soluble photosensitizing pharmaceutical of hypocrellin A (HA), prepared by embedding HA into porous hollow silica nanospheres, exhibited high singlet oxygen generation yield, good light stability and good thermal stability. Further, the in-vitro experiments indicated that such silica nanospheres containing HA can be efficiently taken up by HeLa cells, and light irradiation of such impregnated cells might result in significant cell death. Especially, HA cannot be released from silica nanospheres, which is beneficial to minimizing phototoxic side effects. Thus, these properties of HA-silica nanospheres could possibly make it especially promising to be used in clinical photodynamic therapy. \u00a9 2008 Elsevier B.V. All rights reserved.",
        "keywords": [
            "Hypocrellin A",
            "No-release",
            "Photodynamic therapy",
            "Silica nanospheres",
            "Sol-gel preparation"
        ],
        "venue": "Materials Letters",
        "year": 2008,
        "id": "Me3n42u5"
    },
    "lyXqJsyM": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Department of Physics"
            },
            {
                "name": "Yongyuan Zhu",
                "org": "National Laboratory of Solid State Microstructures"
            }
        ],
        "title": "Propagation characteristics of surface plasmon polaritons in a metal heterowaveguide array",
        "abstract": "A new scheme of one-dimensional metal heterowaveguide array is proposed that the core layer of the metal waveguide is periodically modulated. Numerical results reveal that, periodic modulation of the core layer of metal waveguide induces the periodic modulation of the effective refraction index of the surface plasmon polaritons (SPP) in the waveguide, which opens up an SPP band gap around a certain waveband, such as waveband around 1550 nm. Further numerical results reveal that, the SPP mode resonance with high quality for example Q=556 can be obtained at some wavelength by introducing a proper defect waveguide layer. The results can be applied to the subwavelength Bragg reflectors, light emitters and filters, and could be also available for the future integrated optics.",
        "keywords": [
            "Effective refraction index",
            "Finite-difference time-domain method",
            "Metal waveguide",
            "Surface plasmon polaritons"
        ],
        "venue": "Guangxue Xuebao/Acta Optica Sinica",
        "year": 2008,
        "id": "lyXqJsyM"
    },
    "56lWF1nY": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Yongyuan Zhu",
                "org": ""
            }
        ],
        "title": "Coupling effect of surface plasmon polaritons in single-negative lamellar heterostructure",
        "abstract": "Propagation characteristics of surface plasmon polaritons (SPP",
        "keywords": [
            ""
        ],
        "venue": "Chinese Optics Letters",
        "year": 2008,
        "id": "56lWF1nY"
    },
    "4LcTKFwP": {
        "authors": [
            {
                "name": "Jiahong Zhou",
                "org": "Analysis and Testing Center"
            },
            {
                "name": "Xiaohong Wu",
                "org": "Analysis and Testing Center"
            },
            {
                "name": "Xiaotian Gu",
                "org": "Analysis and Testing Center"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Life Science"
            },
            {
                "name": "Kaixi Song",
                "org": "Analysis and Testing Center"
            },
            {
                "name": "Shaohua Wei",
                "org": "Analysis and Testing Center"
            },
            {
                "name": "Yuying Feng",
                "org": "Analysis and Testing Center"
            },
            {
                "name": "Jian Shen",
                "org": "Analysis and Testing Center"
            }
        ],
        "title": "Spectroscopic studies on the interaction of hypocrellin A and hemoglobin",
        "abstract": "The spectrophotometric and spectrofluorimetric studies revealed that hemoglobin (Hb) could interact with hypocrellin A, a photosensitizing drug used in photodynamic therapy. It was found that this kind of interaction can induce the conformational changes in Hb. In addition, based on fluorescence quenching titration and electron paramagnetic resonance spectroscopy results, the binding parameters, thermodynamic parameters are obtained. The quenching mechanism is also proposed. Crown Copyright \u00a9 2008.",
        "keywords": [
            "Electron paramagnetic resonance spectroscopy",
            "Fluorescence spectroscopy",
            "Hemoglobin",
            "Hypocrellin A",
            "UV-vis absorption spectroscopy"
        ],
        "venue": "Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy",
        "year": 2009,
        "id": "4LcTKFwP"
    },
    "cVv0V2fy": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Jia-Hong Zhou",
                "org": ""
            },
            {
                "name": "Chao Dong",
                "org": ""
            },
            {
                "name": "Fei Ma",
                "org": ""
            },
            {
                "name": "Shao-Hua Wei",
                "org": ""
            },
            {
                "name": "Jian Shen",
                "org": ""
            }
        ],
        "title": "Water-soluble hypocrellin A nanoparticles as a photodynamic therapy delivery system",
        "abstract": "A novel delivery system for the hydrophobic photosensitizer, hypocrellin A, has been developed that uses hypocrellin A nanoparticles prepared by a reprecipitation method. In comparison to the unmodified photosensitizer, the hypocrellin A nanoparticles not only possess superior water solubility, higher water and light stability but also display high singlet oxygen production and DNA photocleavage capability. \u00a9 2008 Elsevier Ltd. All rights reserved.",
        "keywords": [
            "Hypocrellin A",
            "Nanoparticle",
            "Photodynamic therapy",
            "Singlet oxygen quantum yield",
            "Stability",
            "Water-soluble"
        ],
        "venue": "Dyes and Pigments",
        "year": 2009,
        "id": "cVv0V2fy"
    },
    "bdwUu7Ro": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Department of Complex Presection"
            },
            {
                "name": "Chao Dong",
                "org": "Analysis and Testing Center"
            },
            {
                "name": "Shao Hua Wei",
                "org": "Analysis and Testing Center"
            },
            {
                "name": "Yu Ying Feng",
                "org": "Analysis and Testing Center"
            },
            {
                "name": "Jia Hong Zhou",
                "org": "Analysis and Testing Center"
            },
            {
                "name": "Ji Hua Liu",
                "org": "Department of Complex Presection"
            }
        ],
        "title": "Water-soluble soft nano-colloid for drug delivery",
        "abstract": "Photodynamic therapy (PDT) has been proved to be highly effective in the treatment of different types of cancer. A novel nano-colloid based drug carrier for PDT of elsinochrome A (EA), a hydrophobic photosensitizer, was prepared using single 3-aminopropyltriethoxysilane (APTES) which is traditionally only used as surface modification reagent. The resulting nano-colloid immobilized photosensitizers provide good water solubility and photostability. In addition, EANC preserve the key step of photogeneration of singlet oxygen, necessary for photodynamic action. Moreover, significant damage to calf thymus DNA was observed upon irradiation with light. Thus, the potential of using nano-colloid as drug carriers for photodynamic therapy has been demonstrated. \u00a9 2009 Elsevier B.V. All rights reserved.",
        "keywords": [
            "Elsinochrome A",
            "Nanomaterials",
            "Photodynamic efficacy",
            "Photostability",
            "Sol-gel preparation",
            "Water solubility"
        ],
        "venue": "Materials Letters",
        "year": 2009,
        "id": "bdwUu7Ro"
    },
    "rwE0O5NT": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Ji Hua Liu",
                "org": ""
            },
            {
                "name": "Shao Hua Wei",
                "org": ""
            },
            {
                "name": "Yu Ying Feng",
                "org": ""
            },
            {
                "name": "Ji Hong Zhou",
                "org": ""
            },
            {
                "name": "Bo Yang Yu",
                "org": ""
            }
        ],
        "title": "DNA combining and photocleaving properties of photosensitizer-encapsulated silica nanoparticles",
        "abstract": "Based on theoretical predictions, water-soluble silica nanoparticle encapsulated hypocrellin A (HA) was prepared, and its photosensitization activity was evaluated. The encapsulated HA showed not only very good water solubility, but also much stronger singlet oxygen generation ability than free HA. Investigations on binding interactions with DNA showed promising results as well. These findings suggest that HA carrier can exert photodynamic action via photosensitization. \u00a9 2009 Springer-Verlag.",
        "keywords": [
            "Hypocrellin A",
            "Nanostructures",
            "Photochemistry",
            "Silicon compounds",
            "Singlet oxygen"
        ],
        "venue": "Monatshefte fur Chemie",
        "year": 2009,
        "id": "rwE0O5NT"
    },
    "abts6woY": {
        "authors": [
            {
                "name": "Shan Wu",
                "org": "National Laboratory of Solid State Microstructures"
            },
            {
                "name": "Guodong Wang",
                "org": "National Laboratory of Solid State Microstructures"
            },
            {
                "name": "Qianjin Wang",
                "org": "National Laboratory of Solid State Microstructures"
            },
            {
                "name": "Lin Zhou",
                "org": "National Laboratory of Solid State Microstructures"
            },
            {
                "name": "Junwei Zhao",
                "org": "National Laboratory of Solid State Microstructures"
            },
            {
                "name": "Chengping Huang",
                "org": "National Laboratory of Solid State Microstructures"
            },
            {
                "name": "Yongyuan Zhu",
                "org": "National Laboratory of Solid State Microstructures"
            }
        ],
        "title": "Novel optical transmission property of metal-dielectric multilayered structure",
        "abstract": "A kind of planar metal-dielectric multilayered plasmonic structure has been proposed and its optical properties have been studied. Numerical calculations show that both the electric resonance (surface-plasmon polariton resonance) and the magnetic resonance (localized magnetic-plasmon resonance) can enhance the optical transmission. Moreover, by modulating the dimensions of the proposed structure, a large resonance quality factor and a continuum resonance can be achieved. These controllable optical properties might be useful for various practical implementations. \u00a9 2009 IOP Publishing Ltd.",
        "keywords": [
            ""
        ],
        "venue": "Journal of Physics D: Applied Physics",
        "year": 2009,
        "id": "abts6woY"
    },
    "Sn7Ia5xi": {
        "authors": [
            {
                "name": "Xiqi Zhang",
                "org": "PCFM Lab"
            },
            {
                "name": "Zhenguo Chi",
                "org": "DSAPM Lab"
            },
            {
                "name": "Zhiyong Yang",
                "org": "PCFM Lab"
            },
            {
                "name": "Meina Chen",
                "org": "PCFM Lab"
            },
            {
                "name": "Bingjia Xu",
                "org": "PCFM Lab"
            },
            {
                "name": "Lin Zhou",
                "org": "PCFM Lab"
            },
            {
                "name": "Chengcheng Wang",
                "org": "PCFM Lab"
            },
            {
                "name": "Yi Zhang",
                "org": "DSAPM Lab"
            },
            {
                "name": "Siwei Liu",
                "org": "DSAPM Lab"
            },
            {
                "name": "Jiarui Xu",
                "org": "DSAPM Lab"
            }
        ],
        "title": "Synthesis of carbazole derivatives with high quantum yield and high glass transition temperature",
        "abstract": "A series of fluorescent compounds derived from carbazole were synthesized via the Wittig-Horner reaction. The compounds had high glass transition temperatures (T",
        "keywords": [
            "Carbazole derivatives",
            "High glass transition temperature",
            "High quantum yield"
        ],
        "venue": "Optical Materials",
        "year": 2009,
        "id": "Sn7Ia5xi"
    },
    "BatKozPF": {
        "authors": [
            {
                "name": "Zhiyong Yang",
                "org": "PCFM Lab"
            },
            {
                "name": "Zhenguo Chi",
                "org": "DSAPM Lab"
            },
            {
                "name": "Lin Zhou",
                "org": "PCFM Lab"
            },
            {
                "name": "Xiqi Zhang",
                "org": "PCFM Lab"
            },
            {
                "name": "Meina Chen",
                "org": "PCFM Lab"
            },
            {
                "name": "Bingjia Xu",
                "org": "PCFM Lab"
            },
            {
                "name": "Chengcheng Wang",
                "org": "PCFM Lab"
            },
            {
                "name": "Yi Zhang",
                "org": "DSAPM Lab"
            },
            {
                "name": "Jiarui Xu",
                "org": "DSAPM Lab"
            }
        ],
        "title": "Blue-light-emitting carbazole derivates with high thermal stability",
        "abstract": "A new series of fluorescent compounds containing tricarbazolyl groups have been synthesized. The compounds have very high glass transition temperatures in the range 243-266 \u00b0C, high decomposition temperatures of 506-527 \u00b0C, and exhibit strong blue fluorescence with maximum emission wavelengths at 445-457 nm. The compounds have good solubility in common solvents even though they contain rather rigid wholly aromatic structures. The thermal stability of these compounds exhibits a marked odd-even effect corresponding to the number of phenylene bridges in the compound. In the solid, the maximum photoluminescence emission wavelength with n odd have a slight bathochromic shift in comparison to those with n even. \u00a9 2009 Elsevier B.V. All rights reserved.",
        "keywords": [
            "Blue light emission",
            "High glass transition temperature",
            "Optical materials and properties",
            "Thermal properties",
            "Tricarbazolyl derivatives"
        ],
        "venue": "Optical Materials",
        "year": 2009,
        "id": "BatKozPF"
    },
    "zBCDG6Jp": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Ji-Hua Liu",
                "org": ""
            },
            {
                "name": "Jian Zhang",
                "org": ""
            },
            {
                "name": "Shao-Hua Wei",
                "org": ""
            },
            {
                "name": "Yu-Ying Feng",
                "org": ""
            },
            {
                "name": "Jia-Hong Zhou",
                "org": ""
            },
            {
                "name": "Bo-Yang Yu",
                "org": ""
            },
            {
                "name": "Jian Shen",
                "org": ""
            }
        ],
        "title": "A new sol-gel silica nanovehicle preparation for photodynamic therapy in vitro",
        "abstract": "We report a facile silica nanovehicle preparation procedure for hydrophobic drug delivery, which is carried out in water without adding any surfactant and additional catalyst. This strategy includes hydrophobic drug nanopaticle preparation by reprecipitation method and in situ hydrolyzation and polymerization to encapsulate this naoparticle using only N-(\u03b2-amimoethyl)-\u03b3-aminopropyltyiethoxysilane (AETPS). To demonstrate this technique hypocrellin A (HA), a hydrophobic photosensitizing anticancer drug, is embedded into silica nanovehicle using this simple method. The resulting HA encapsulated nanovehicles (HANV) are monodisperse and stable in aqueous solution. Comparative studies with free HA and entrapped HA have demonstrated that the encapsulation effect on the embedded photosensitizer nanoparticle significantly enhances the efficacy of singlet oxygen generation and, thereby, the in vitro photodynamic efficacy. \u00a9 2009 Elsevier B.V. All rights reserved.",
        "keywords": [
            "Drug delivery system",
            "Hypocrellin A",
            "Photodynamic therapy",
            "Silica nanovehicle"
        ],
        "venue": "International Journal of Pharmaceutics",
        "year": 2010,
        "id": "zBCDG6Jp"
    },
    "xs0ZYuOp": {
        "authors": [
            {
                "name": "Shan Wu",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Yu-Min Wang",
                "org": ""
            },
            {
                "name": "Guo-Dong Wang",
                "org": ""
            },
            {
                "name": "Qian-Jin Wang",
                "org": ""
            },
            {
                "name": "Cheng-Ping Huang",
                "org": ""
            },
            {
                "name": "Yong-Yuan Zhu",
                "org": ""
            }
        ],
        "title": "Optical properties of a metal film perforated with coaxial elliptical hole arrays",
        "abstract": "The optical properties of a metal film perforated with coaxial elliptical hole arrays have been investigated experimentally and a simple analysis model that qualitatively explains the experimental results has been presented. In our structure, two localized excitations, i.e., the short- and long-axis localized surface-plasmon modes of the elliptical nanoparticles or nanoholes can be excited, which couples, respectively, with the surface-plasmon polariton modes and causes different optical response. As a consequence, the transmission features can be manipulated by the polarization state of the incident light. \u00a9 2010 The American Physical Society.",
        "keywords": [
            ""
        ],
        "venue": "Physical Review E - Statistical, Nonlinear, and Soft Matter Physics",
        "year": 2010,
        "id": "xs0ZYuOp"
    },
    "7qOQ3aR4": {
        "authors": [
            {
                "name": "Shan Wu",
                "org": "National Laboratory of Solid State Microstructures"
            },
            {
                "name": "Lin Zhou",
                "org": "National Laboratory of Solid State Microstructures"
            },
            {
                "name": "Yu-Min Wang",
                "org": "National Laboratory of Solid State Microstructures"
            },
            {
                "name": "Cheng-Ping Huang",
                "org": "Department of Applied Physics"
            },
            {
                "name": "Qian-Jin Wang",
                "org": "National Laboratory of Solid State Microstructures"
            },
            {
                "name": "Guo-Dong Wang",
                "org": "National Laboratory of Solid State Microstructures"
            },
            {
                "name": "Yong-Yuan Zhu",
                "org": "National Laboratory of Solid State Microstructures"
            }
        ],
        "title": "Phaselike resonance behavior in optical transmission of sandwich coaxial square ring arrays",
        "abstract": "We studied the optical transmission through sandwich coaxial square ring arrays experimentally and theoretically. The hybridized mode of the localized surface-plasmons and surface-plasmon polaritons has been observed. This hybridized mode resembles the phase resonance mode in a compound grating structure and can be named as phaselike resonance mode. For the 0-phase resonance mode, energy can tunnel through the sample due to coherent constructive interference, forming a peak in the transmission spectrum. For the \u03c0 -phase resonance mode, a dip appears instead. When the incident angle is increased, the \u03c0 -phase resonance mode is split into two branches, one is redshifted while the other blueshifted. \u00a9 2010 American Institute of Physics.",
        "keywords": [
            ""
        ],
        "venue": "Applied Physics Letters",
        "year": 2010,
        "id": "7qOQ3aR4"
    },
    "W8BsYdcz": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "National Laboratory of Solid State Microstructures"
            },
            {
                "name": "Cheng-Ping Huang",
                "org": "Department of Applied Physics"
            },
            {
                "name": "Shan Wu",
                "org": "National Laboratory of Solid State Microstructures"
            },
            {
                "name": "Xiao-Gang Yin",
                "org": "National Laboratory of Solid State Microstructures"
            },
            {
                "name": "Yu-Min Wang",
                "org": "National Laboratory of Solid State Microstructures"
            },
            {
                "name": "Qian-Jin Wang",
                "org": "National Laboratory of Solid State Microstructures"
            },
            {
                "name": "Yong-Yuan Zhu",
                "org": "National Laboratory of Solid State Microstructures"
            }
        ],
        "title": "Enhanced optical transmission through metal-dielectric multilayer gratings",
        "abstract": "The optical transmission properties of metal-dielectric multilayer gratings have been investigated both experimentally and numerically. A remarkable transmission resonance, which makes a significant difference from that of traditional single/triple-layer analogs, has been reported. To understand its physical origin, a field-interference mechanism of dipole arrays induced by the lateral and vertical plasmon coupling has been suggested. \u00a9 2010 American Institute of Physics.",
        "keywords": [
            ""
        ],
        "venue": "Applied Physics Letters",
        "year": 2010,
        "id": "W8BsYdcz"
    },
    "bcBjnEhR": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Department of Complex Prescription of TCM"
            },
            {
                "name": "Yu-Wei Ning",
                "org": "Xuchang Vocational Technical College"
            },
            {
                "name": "Shao-Hua Wei",
                "org": "Jiangsu Key Laboratory Biofunctional Materials, Analysis and Testing Center"
            },
            {
                "name": "Yu-Ying Feng",
                "org": "Jiangsu Key Laboratory Biofunctional Materials, Analysis and Testing Center"
            },
            {
                "name": "Jia-Hong Zhou",
                "org": "Jiangsu Key Laboratory Biofunctional Materials, Analysis and Testing Center"
            },
            {
                "name": "Bo-Yang Yu",
                "org": "Department of Complex Prescription of TCM"
            },
            {
                "name": "Jian Shen",
                "org": "Jiangsu Key Laboratory Biofunctional Materials, Analysis and Testing Center"
            }
        ],
        "title": "A nanoencapsulated hypocrellin A prepared by an improved microemulsion method for photodynamic treatment",
        "abstract": "A new hypocrellin A (HA) encapsulated silica nanoparticles was prepared by an improved microemulsion method based on the unique character of cetyl trimethyl ammonium bromide (CTAB). Stable aqueous dispersions of the HA-loaded nanoparticles, with the diameter about 50 nm, owned superior photo-stability and singlet oxygen generation ability to free HA. In vitro studies demonstrated the active uptake of HA-doped nanoparticles into the cytosol of HeLa (human cervix epithelioid carcinoma) cells. Significant morphology change and phototoxicity to such impregnated tumor cells was observed upon irradiation with light. Thus, the potential of using this method to prepare silica nanoparticles as drug carriers for photodynamic therapy has been demonstrated. \u00a9 2010 Springer Science+Business Media, LLC.",
        "keywords": [
            ""
        ],
        "venue": "Journal of Materials Science: Materials in Medicine",
        "year": 2010,
        "id": "bcBjnEhR"
    },
    "3LCzCAjw": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Analysis and Testing Center"
            },
            {
                "name": "Ji-Hua Liu",
                "org": "Department of Complex Prescription of TCM"
            },
            {
                "name": "Fei Ma",
                "org": "Analysis and Testing Center"
            },
            {
                "name": "Shao-Hua Wei",
                "org": "Analysis and Testing Center"
            },
            {
                "name": "Yu-Ying Feng",
                "org": "Analysis and Testing Center"
            },
            {
                "name": "Jia-Hong Zhou",
                "org": "Analysis and Testing Center"
            },
            {
                "name": "Bo-Yang Yu",
                "org": "Department of Complex Prescription of TCM"
            },
            {
                "name": "Jian Shen",
                "org": "Analysis and Testing Center"
            }
        ],
        "title": "Mitochondria-targeting photosensitizer-encapsulated amorphous nanocage as a bimodal reagent for drug delivery and biodiagnose in vitro",
        "abstract": "The use of ceramic nano-carriers containing anticancer drugs for targeted delivery that span both fundamental and applied research has attracted the interest of the scientific community. In this paper, a hydrophobic photodynamic therapy drug, hypocrellin A (HA), was successfully encapsulated in water-soluble amorphous silica nanocage (HANC) by an improved sol-gel method. These nanocages are of ultrasmall size, highly monodispersed, stable in aqueous suspension, and retain the optical properties of HA. Moreover, these nanocages can be effectively delivered, subsequently taken up by cancer cells and finally targeted to mitochondria. In addition, incubation time dependent photodynamic efficacy difference between HANC and HA was investigated for the first time. Especially, the nanocages, owning extremely high stable fluorescence comparing with free HA, also have potentials as efficient probes for optical biodiagnose in vitro. All these properties of HANC could possibly make it especially promising to be used as a bimodal reagent for photodynamic therapy and biodiagnose. \u00a9 Springer Science+Business Media, LLC 2010.",
        "keywords": [
            "Amorphous silica-nanocage time-dependent efficacy",
            "Biodiagnose",
            "Drug delivery",
            "Mitochondria-targeting",
            "Photodynamic"
        ],
        "venue": "Biomedical Microdevices",
        "year": 2010,
        "id": "3LCzCAjw"
    },
    "YsfIxiUL": {
        "authors": [
            {
                "name": "Fang Wang",
                "org": "Jiangsu Testing Service Center for Biomedicinal Materials"
            },
            {
                "name": "Lin Zhou",
                "org": "Complex Presection of CMM"
            },
            {
                "name": "Jiahong Zhou",
                "org": "Jiangsu Testing Service Center for Biomedicinal Materials"
            },
            {
                "name": "Xiaotian Gu",
                "org": "Jiangsu Testing Service Center for Biomedicinal Materials"
            },
            {
                "name": "Yuying Feng",
                "org": "Jiangsu Testing Service Center for Biomedicinal Materials"
            }
        ],
        "title": "Characterization of anticancer hypocrellin A encapsulated with silica nanoparticles Thermal analysis",
        "abstract": "Hypocrellins, natural photosensitizers including hypocrellin A (HA) and hypocrellin B (HB), have been used as a traditional Chinese herbal medicine to cure various skin diseases. Hypocrellins have excellent antiviral activity, which can inhibit the growth of human immunodeficiency virus. They also exhibit significant light-induced antitumor property. In this article, thermal analysis technologies (e.g., differential scanning calorimetry and thermogravimetry) are employed to characterize whether the photosensitive hypocrellin A could be encapsulated with silica nanoparticle (SN) material or not, and evaluate the stability of inclusion complex. The results show that the inclusion complex exhibits improved performance in both stability and hydrophilicity than natural hypocrellin A. Fluorescence spectrophotometry studies have also been performed to verify the thermal analysis results. The results suggest that the thermal analysis technology could be used as an effective and rapid tool to characterize the encapsulation properties of the novel anticancer HA-SN complex. \u00a9 2010 Akad\u00e9miai Kiad\u00f3, Budapest, Hungary.",
        "keywords": [
            "Differential scanning calorimetry",
            "Hypocrellin",
            "Silica nanoparticle",
            "Thermogravimetry"
        ],
        "venue": "Journal of Thermal Analysis and Calorimetry",
        "year": 2010,
        "id": "YsfIxiUL"
    },
    "KhvwsbJK": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Department of Complex Prescription of TCM"
            },
            {
                "name": "Wei Wang",
                "org": "Analysis and Testing Center"
            },
            {
                "name": "Yuying Feng",
                "org": "Analysis and Testing Center"
            },
            {
                "name": "Shaohua Wei",
                "org": "Analysis and Testing Center"
            },
            {
                "name": "Jiahong Zhou",
                "org": "Analysis and Testing Center"
            },
            {
                "name": "Boyang Yu",
                "org": "Department of Complex Prescription of TCM"
            },
            {
                "name": "Jian Shen",
                "org": "Analysis and Testing Center"
            }
        ],
        "title": "Delivering a hydrophobic anticancer drug for photodynamic therapy by amorphous formulation",
        "abstract": "An amorphous formulation of hypocrellin A for photodynamic therapy is reported which can provide stable aqueous dispersion of such hydrophobic photosensitizers. In vitro studies have demonstrated the active uptake of amorphous formulation of hypocrellin A into the mitochondria of tumor cells. Compared with Tween-80 micelle embedded hypocrellin A, low dark-toxicity but similar light-toxicity of the amorphous one to drug impregnated tumor cells was observed. Thus, the potential of using amorphous formulation of hypocrellin A as drug delivery system for photodynamic therapy has been demonstrated. \u00a9 2010 Elsevier Ltd. All rights reserved.",
        "keywords": [
            "Amorphous formulation",
            "Drug delivery system",
            "Hypocrellin A",
            "Photodynamic therapy"
        ],
        "venue": "Bioorganic and Medicinal Chemistry Letters",
        "year": 2010,
        "id": "KhvwsbJK"
    },
    "nkjenqvX": {
        "authors": [
            {
                "name": "Zhenguo Chi",
                "org": "State Key Laboratory of Optoelectronic Materials and Technologies"
            },
            {
                "name": "Xiaofang Li",
                "org": "State Key Laboratory of Optoelectronic Materials and Technologies"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Optoelectronic Materials and Technologies"
            },
            {
                "name": "Haiyin Li",
                "org": "State Key Laboratory of Optoelectronic Materials and Technologies"
            },
            {
                "name": "Bingjia Xu",
                "org": "State Key Laboratory of Optoelectronic Materials and Technologies"
            },
            {
                "name": "Wei Zhou",
                "org": "State Key Laboratory of Optoelectronic Materials and Technologies"
            },
            {
                "name": "Yi Zhang",
                "org": "State Key Laboratory of Optoelectronic Materials and Technologies"
            },
            {
                "name": "Jiarui Xu",
                "org": "State Key Laboratory of Optoelectronic Materials and Technologies"
            }
        ],
        "title": "Synthesis and properties of tert-butylphenyl carbazole derivatives with high thermal stabilities and high fluorescent quantum yields",
        "abstract": "The novel tert-butylphenyl carbazole derivatives were synthesized by Wittig-Horner reactions. The chemical structures of the derivatives were determined by ",
        "keywords": [
            "High fluorescent quantum yields",
            "High thermal stabilities",
            "Organic luminescent materials",
            "Tert-butylphenyl carbazole derivatives"
        ],
        "venue": "Zhongshan Daxue Xuebao/Acta Scientiarum Natralium Universitatis Sunyatseni",
        "year": 2010,
        "id": "nkjenqvX"
    },
    "oOQWerQb": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Department of Physics, Nanjing Xiaozhuang University"
            },
            {
                "name": "Qian-Jin Wang",
                "org": "National Laboratory of Solid State Microstructures, Nanjing University"
            },
            {
                "name": "Shan Wu",
                "org": "National Laboratory of Solid State Microstructures, Nanjing University"
            },
            {
                "name": "Wan-Xia Huang",
                "org": "National Laboratory of Solid State Microstructures, Nanjing University"
            },
            {
                "name": "Cheng-Ping Huang",
                "org": "Department of Applied Physics, Nanjing University of Technology"
            },
            {
                "name": "Yong-Yuan Zhu",
                "org": "National Laboratory of Solid State Microstructures, Nanjing University"
            }
        ],
        "title": "Hybrid of surface plasmon polaritons and waveguide resonances through double-layer metallic gratings",
        "abstract": "The optical properties of double-layer close-packed metallic gratings have been systematically studied. Apart from the optical transmission enhancement, we report the double-mode oscillation as the metal layer thickness increases beyond a critical value, which is related to the hybrid between two types of surface plasmon polariton and different orders of waveguide resonance inside the air cavity. To further improve our understanding of the physical mechanism involved, a field-interference mechanism of dipole array, induced by both lateral and vertical plasmon coupling, has been employed. \u00a9 2011 Optical Society of America.",
        "keywords": [
            ""
        ],
        "venue": "Journal of the Optical Society of America B: Optical Physics",
        "year": 2011,
        "id": "oOQWerQb"
    },
    "HUMLZkMw": {
        "authors": [
            {
                "name": "Xiao-Gang Yin",
                "org": "National Laboratory of Solid State Microstructures, Nanjing University"
            },
            {
                "name": "Cheng-Ping Huang",
                "org": "Department of Applied Physics, Nanjing University of Technology"
            },
            {
                "name": "Qian-Jin Wang",
                "org": "National Laboratory of Solid State Microstructures, Nanjing University"
            },
            {
                "name": "Wan-Xia Huang",
                "org": "National Laboratory of Solid State Microstructures, Nanjing University"
            },
            {
                "name": "Lin Zhou",
                "org": "National Laboratory of Solid State Microstructures, Nanjing University"
            },
            {
                "name": "Chao Zhang",
                "org": "National Laboratory of Solid State Microstructures, Nanjing University"
            },
            {
                "name": "Yong-Yuan Zhu",
                "org": "National Laboratory of Solid State Microstructures, Nanjing University"
            }
        ],
        "title": "Fanolike resonance due to plasmon excitation in linear chains of metal bumps",
        "keywords": [
            ""
        ],
        "venue": "Optics Express",
        "year": 2011,
        "id": "HUMLZkMw"
    },
    "o40UAWRR": {
        "authors": [
            {
                "name": "Fei Ma",
                "org": "Key Lab. of Biofunction Materials of Jiangsu"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Lab. of Biofunction Materials of Jiangsu"
            },
            {
                "name": "Wei Wang",
                "org": "Key Lab. of Biofunction Materials of Jiangsu"
            },
            {
                "name": "Yu-Ying Feng",
                "org": "Key Lab. of Biofunction Materials of Jiangsu"
            },
            {
                "name": "Jia-Hong Zhou",
                "org": "Key Lab. of Biofunction Materials of Jiangsu"
            },
            {
                "name": "Xing-He Wang",
                "org": "Department of Physical Science and Technology"
            },
            {
                "name": "Jian Shen",
                "org": "Key Lab. of Biofunction Materials of Jiangsu"
            }
        ],
        "title": "Spectroscopic studies on the interaction of Elsinochrome A with myoglobin",
        "abstract": "The interaction between Elsinochrome A (EA) and myoglobin (Mb) was investigated using UV-Vis and fluorescence spectroscopy. The results suggested that there was a strong interaction between EA and Mb. In the dark, the interaction occurred on the surfaces amidic acid of Mb, but when illuminated, the interactions happened both on amidic acid and the interior structure of hemachrome of Mb. According to the values of the quenching constant, the thermodynamics parameters, the binding constants and the binding sites, it was showed that the binding interaction of EA and Mb was mainly hydrophobic in nature and the quenching mechanism was static quenching procedure. The change in the micro-circumstance of aminos of myoglobin was studied by synchronous fluorescence spectroscopy.",
        "keywords": [
            "Elsinochrome A",
            "Fluorescence spectroscopy",
            "Myoglobin",
            "UV-Vis spectroscopy"
        ],
        "venue": "Guang Pu Xue Yu Guang Pu Fen Xi/Spectroscopy and Spectral Analysis",
        "year": 2011,
        "id": "o40UAWRR"
    },
    "cf4wjmZg": {
        "authors": [
            {
                "name": "Jian-Qiang Liu",
                "org": ""
            },
            {
                "name": "Meng-Dong He",
                "org": ""
            },
            {
                "name": "San Chen",
                "org": ""
            },
            {
                "name": "Cheng-Ping Huang",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Yong-Yuan Zhu",
                "org": ""
            }
        ],
        "title": "Electromagnetic interaction in stacked split ring resonator arrays",
        "abstract": "We theoretically demonstrate the coupling between the unit cells and the interaction between constituents within each cell in metamaterials consisting of stacked split ring resonator arrays which are embedded in a homogeneous dielectric. It is found that the resonant frequency due to plasmon hybridization depends on the symmetry of resonance modes. Both for the first and third order plasmon resonances, we show that the resonances at lower frequency are not sensitive to the variation of lattice density, while the resonances at higher frequency rely on the coupling between cells due to the symmetric distribution of current. The underlying physics is qualitatively interpreted according to the quasistatic electric and magnetic dipole coupling model combined by the calculated field distributions. \u00a9 2011 IOP Publishing Ltd.",
        "keywords": [
            ""
        ],
        "venue": "Journal of Physics Condensed Matter",
        "year": 2011,
        "id": "cf4wjmZg"
    },
    "5CbVArKR": {
        "authors": [
            {
                "name": "Wan-Xia Huang",
                "org": "National Laboratory of Solid State Microstructures"
            },
            {
                "name": "Yi Zhang",
                "org": "National Laboratory of Solid State Microstructures"
            },
            {
                "name": "Xia-Mei Tang",
                "org": "National Laboratory of Solid State Microstructures"
            },
            {
                "name": "Li-Sha Cai",
                "org": "National Laboratory of Solid State Microstructures"
            },
            {
                "name": "Jun-Wei Zhao",
                "org": "National Laboratory of Solid State Microstructures"
            },
            {
                "name": "Lin Zhou",
                "org": "National Laboratory of Solid State Microstructures"
            },
            {
                "name": "Qian-Jin Wang",
                "org": "National Laboratory of Solid State Microstructures"
            },
            {
                "name": "Cheng-Ping Huang",
                "org": "Department of Applied Physics"
            },
            {
                "name": "Yong-Yuan Zhu",
                "org": "National Laboratory of Solid State Microstructures"
            }
        ],
        "title": "Optical properties of a planar metamaterial with chiral symmetry breaking",
        "abstract": "The optical properties of a planar metamaterial with gammadion-shaped chiral symmetry breaking holes array have been investigated both theoretically and experimentally. The results indicate that the introduction of the chiral symmetry breaking causes the split of the transmission peak and exerts large influence on the optical rotation and circular dichroism. Our metamaterials might have potential applications in future design of plasmonic devices. \u00a9 2011 Optical Society of America.",
        "keywords": [
            ""
        ],
        "venue": "Optics Letters",
        "year": 2011,
        "id": "5CbVArKR"
    },
    "bmafQOJ8": {
        "authors": [
            {
                "name": "Shan Wu",
                "org": "Department of Physics"
            },
            {
                "name": "Jianqiang Liu",
                "org": "National Laboratory of Solid State Microstructures"
            },
            {
                "name": "Lin Zhou",
                "org": "National Laboratory of Solid State Microstructures"
            },
            {
                "name": "Qianjin Wang",
                "org": "National Laboratory of Solid State Microstructures"
            },
            {
                "name": "Yi Zhang",
                "org": "National Laboratory of Solid State Microstructures"
            },
            {
                "name": "Guodong Wang",
                "org": "National Laboratory of Solid State Microstructures"
            },
            {
                "name": "Yongyuan Zhu",
                "org": "National Laboratory of Solid State Microstructures"
            }
        ],
        "title": "Electric quadrupole excitation in surface plasmon resonance of metallic composite nanohole arrays",
        "abstract": "We present an experimental and theoretical study on the composite nanostructures composed of the LT-shaped metallic nanohole arrays. Multiple resonance transmission peaks are observed in the optical transmission spectra. By analyzing their electric field distributions on the interface, we infer the electric dipole and the electric quadrupole plasmonic resonances contribute to these transmission peaks. The electric quadrupole is a subradiant mode, which cannot be directly excited by the incident light. Here, we demonstrate that the surface plasmon polaritons can excite the electric quadrupole plasmonic resonance mode through the near-field interaction. \u00a9 2011 American Institute of Physics.",
        "keywords": [
            ""
        ],
        "venue": "Applied Physics Letters",
        "year": 2011,
        "id": "bmafQOJ8"
    },
    "YWDVCFml": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Analysis and Testing Center"
            },
            {
                "name": "Wei Wang",
                "org": "Analysis and Testing Center"
            },
            {
                "name": "Jing Tang",
                "org": "Analysis and Testing Center"
            },
            {
                "name": "Jia-Hong Zhou",
                "org": "Analysis and Testing Center"
            },
            {
                "name": "Hui-Jun Jiang",
                "org": "School of Pharmacy"
            },
            {
                "name": "Jian Shen",
                "org": "Analysis and Testing Center"
            }
        ],
        "title": "Graphene oxide noncovalent photosensitizer and its anticancer activity in vitro",
        "abstract": "Graphene oxide (GO) was investigated as a potential drug-delivery system due to its special properties and biocompatibility. Thus far, little has been done to use GO as a photosensitive drug-delivery system and to explore its anticancer activity in vitro in photodynamic therapy applications. Here, a novel GO-hypocrellin A (GO-HA) hybrid was prepared by a simple noncovalent method and its photodynamic activity was studied for the first time. The results showed that an efficient loading amount of HA on GO was as high as 1.0 mg mg ",
        "keywords": [
            "antitumor agents",
            "drug delivery",
            "graphene",
            "photodynamic therapy",
            "photosensitizers"
        ],
        "venue": "Chemistry - A European Journal",
        "year": 2011,
        "id": "YWDVCFml"
    },
    "Qag7VnEv": {
        "authors": [
            {
                "name": "Xiaoqiang Yu",
                "org": "Physics Department"
            },
            {
                "name": "Yanfeng Bai",
                "org": "Physics Department"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Physics and Electrical Engineering"
            }
        ],
        "title": "Multi-resonant plasmonic transmission in a dual-periodically arranged metal-insulator-metal waveguide",
        "abstract": "A metallic heterowaveguide array, which is alternatively stacked by two kinds of metal-insulatormetal waveguides in a dual-periodic arrangement, has been investigated numerically. Based on the transfer matrix method and the principle of plasmon Bragg reflector, multi-resonant surface plasmon modes with high quality factors have been predicted in the structure. The number of the resonant modes, the corresponding center wavelengths as well as the mode intervals can be controlled flexibly by adjusting the structure parameters. Numerical simulations performed by the finite element method show good agreement with the predication of the transfer matrix method. Our results could be applied for the future surface-plasmon based wavelength division multiplexers at the telecommunication band, multi-channel filters, and multi-wavelength light-emitting diodes. Copyright \u00a9 2011 American Scientific Publishers All rights reserved.",
        "keywords": [
            "Dual-periodic multi-resonance",
            "Metal-insulator-metal waveguide"
        ],
        "venue": "Journal of Nanoscience and Nanotechnology",
        "year": 2011,
        "id": "Qag7VnEv"
    },
    "DIk2QxZa": {
        "authors": [
            {
                "name": "Fei Ma",
                "org": "Jiangsu Key Laboratory Biofunctional Materials"
            },
            {
                "name": "Jing Tang",
                "org": "Jiangsu Key Laboratory Biofunctional Materials"
            },
            {
                "name": "Chao Yang",
                "org": "Jiangsu Key Laboratory Biofunctional Materials"
            },
            {
                "name": "Yu-Ying Feng",
                "org": "Jiangsu Key Laboratory Biofunctional Materials"
            },
            {
                "name": "Shao-Hua Wei",
                "org": "Jiangsu Key Laboratory Biofunctional Materials"
            },
            {
                "name": "Jian Shen",
                "org": "Jiangsu Key Laboratory Biofunctional Materials"
            },
            {
                "name": "Jia-Hong Zhou",
                "org": "Jiangsu Key Laboratory Biofunctional Materials"
            },
            {
                "name": "Lin Zhou",
                "org": "Jiangsu Key Laboratory Biofunctional Materials"
            }
        ],
        "title": "DNA binding and photo-induced DNA cleavage activity of Elsinochrome A in visible light",
        "abstract": "The interaction of Elsinochrome A (EA) with calf thymus DNA (CT-DNA) has been investigated by UV-vis spectra and fluorescence spectra. The results show that EA can bind with CT-DNA and binding sites are destroyed after irradiation by visible light, which indicates that EA is a promising candidate for photodynamic therapy. In addition, the binding mechanism is studied using fluorescence quenching test and ethidium bromide (EB) replace assay experiments. The results suggest that EA and CT-DNA are binding with a strong force and the major binding mode of EA with DNA could be the electrostatic binding. \u00a9 2011 - IOS Press and the authors. All rights reserved.",
        "keywords": [
            "Elsinochrome A",
            "fluorescence quenching",
            "photodamage",
            "thermodynamics parameter"
        ],
        "venue": "Spectroscopy",
        "year": 2011,
        "id": "DIk2QxZa"
    },
    "B97o1bVF": {
        "authors": [
            {
                "name": "Rui Lin",
                "org": "Jiangsu Key Laboratory Biofunctional Materials"
            },
            {
                "name": "Lin Zhou",
                "org": "Jiangsu Key Laboratory Biofunctional Materials"
            },
            {
                "name": "Yun Lin",
                "org": "Jiangsu Key Laboratory Biofunctional Materials"
            },
            {
                "name": "Ao Wang",
                "org": "Jiangsu Key Laboratory Biofunctional Materials"
            },
            {
                "name": "Jia Hong Zhou",
                "org": "Analysis Testing Center"
            },
            {
                "name": "Shao Hua Wei",
                "org": "Jiangsu Key Laboratory Biofunctional Materials"
            }
        ],
        "title": "Property study of a new silica nanoparticle delivery system of hydrophobic phthalocyanine using spectroscopic method",
        "abstract": "Tetra-tert-butyl zinc(II) phthalocyanine has attracted great attention as an effective photosensitizer in the field of photodynamic therapy. However, tetra-tert-butyl zinc(II) phthalocyanine is hydrophobic and trends to aggregate to form the inactive congeries in aqueous solution, which dramatically reduce its photodynamic activity. To solve this problem, tetra-tert-butyl zinc(II) phthalocyanine was encapsulated into silica nanoparticles using microemulsion method and its properties were studied using spectroscopic methods. After embedded inside the silica nanoparticles, the water-solubility, stability and monomer percent of phthalocyanine in water were greatly improved comparing with the free phthalocyanines, and therefore, its photo-induced singlet oxygen generation efficacy of drug-doped silica nanoparticles was improved. The results indicated that encapsulation hydrophobic phthalocyanine into silica nanoparticles was an effective way to solve their problems and promote their clinical application. \u00a9 2011-IOS Press and the authors. All rights reserved.",
        "keywords": [
            "ceramics",
            "nanocomposites",
            "photodynamic therapy",
            "Phthalocyanine"
        ],
        "venue": "Spectroscopy",
        "year": 2011,
        "id": "B97o1bVF"
    },
    "VU5Lh4wG": {
        "authors": [
            {
                "name": "Jing Tang",
                "org": "College of Chemistry and Materials Science"
            },
            {
                "name": "Lin Zhou",
                "org": "College of Chemistry and Materials Science"
            },
            {
                "name": "Fei Ma",
                "org": "College of Chemistry and Materials Science"
            },
            {
                "name": "Chao Yang",
                "org": "College of Chemistry and Materials Science"
            },
            {
                "name": "Jia-Hong Zhou",
                "org": "Analysis and Testing Center"
            }
        ],
        "title": "Synthesis and luminescence properties of nanoparticles embedded with Europium (III)/coumarin complexes",
        "abstract": "A complex of europium (III)/coumarin was synthesized and the complexation reaction was studied by UV-vis, fluorescence, FTIR, ",
        "keywords": [
            "Encapsulation",
            "Europium (III)/coumarin complex",
            "Optical signal",
            "Synthesis"
        ],
        "venue": "Journal of Optoelectronics and Advanced Materials",
        "year": 2012,
        "id": "VU5Lh4wG"
    },
    "xqtBz79G": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Xia-Mei Tang",
                "org": ""
            },
            {
                "name": "Cheng-Ping Huang",
                "org": ""
            },
            {
                "name": "Yi Zhang",
                "org": ""
            },
            {
                "name": "Yong-Yuan Zhu",
                "org": ""
            }
        ],
        "title": "Polarization-tunable polariton excitation in a compound plasmonic crystal",
        "abstract": "Propagation of an electromagnetic (EM) wave through a compound plasmonic crystal composed of perpendicularly arranged gold nanorod pairs has been studied. Because of the strong coupling between the EM wave and vibrations of free electrons inside nanorod pairs, the polarization-tunable polariton stop band as well as pronounced polarization conversion can be achieved in the compound plasmonic crystal. A theory based on Huang-Kun-like equations is presented to reveal the mechanism, which agrees well with the simulations. Our results may shed light on the structure design and physical understandings on the anisotropic metamaterials. \u00a9 2012 American Institute of Physics.",
        "keywords": [
            ""
        ],
        "venue": "Applied Physics Letters",
        "year": 2012,
        "id": "xqtBz79G"
    },
    "P78D6zIl": {
        "authors": [
            {
                "name": "Jing Tang",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials"
            },
            {
                "name": "Lin Zhou",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials"
            },
            {
                "name": "Wei Wang",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials"
            },
            {
                "name": "Chao Yang",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials"
            },
            {
                "name": "Jia Hong Zhou",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials"
            },
            {
                "name": "Yan Huai Zhou",
                "org": "School of Physics and Technology"
            }
        ],
        "title": "A new dual fluorescent probe preparation and its biodiagnose function in vitro",
        "abstract": "A new dual fluorescent probe was prepared by encapsulating the complex of cerium (III) and quinizarin into silica nanoparticles. Cerium (III) and quinizarin can form a stable dual fluorescent complex in ethanol, but this complex would dissociate in the aqueous medium, which limited its application in biosystem. So, such complex was encapsulated inside the silica nanoparticles to solve this problem. The results indicated that the stability and water solubility of the complex were greatly improved after been encapsulated into the silica nanoparticles. In addition, its dual fluorescent probe function was studied in vitro. \u00a9 2012 Elsevier B.V.",
        "keywords": [
            "Cerium (III)/quinizarin complex",
            "Dually fluorescent probes",
            "Fluorescence lifetime",
            "Quantum yields"
        ],
        "venue": "Journal of Luminescence",
        "year": 2012,
        "id": "P78D6zIl"
    },
    "moYUqtRP": {
        "authors": [
            {
                "name": "Rui Qiao",
                "org": "Department of Chemistry"
            },
            {
                "name": "Lin Zhou",
                "org": "Jiangsu Key Laboratory Biofunctional Materials"
            },
            {
                "name": "Jiahong Zhou",
                "org": "Jiangsu Key Laboratory Biofunctional Materials"
            },
            {
                "name": "Shaohua Wei",
                "org": "Jiangsu Key Laboratory Biofunctional Materials"
            },
            {
                "name": "Jian Shen",
                "org": "Jiangsu Key Laboratory Biofunctional Materials"
            },
            {
                "name": "Baowen Zhang",
                "org": "Key Laboratory of Photochemical Conversion and Optoelectronic Materials"
            },
            {
                "name": "Xuesong Wang",
                "org": "Key Laboratory of Photochemical Conversion and Optoelectronic Materials"
            }
        ],
        "title": "The synthesis and characterization of ethylenediamine-modified Elsinochrome A",
        "abstract": "To overcome the lack of appreciable absorption in the phototherapeutic window (600-900 nm) of the naturally occurring perylenequinonoid pigment, Elsinochrome A, which limits its clinical application, an ethylenediamine- modified elsinochrome A, possessing long wavelength absorption (708 nm) was synthesized. Electron paramagnetic resonance and chemiluminescence assays indicated that ethylenediamine-modified Elsinochrome A possessed photosensitizing activity and its photodamage efficacy is greater than that of unmodified Elsinochrome A. \u00a9 2011 Elsevier Ltd. All rights reserved.",
        "keywords": [
            "Elsinochrome A",
            "Ethylenediamine-modified",
            "Longer wavelength absorption",
            "Photodamage efficacy",
            "Photodynamic therapy",
            "Photosensitizing activity"
        ],
        "venue": "Dyes and Pigments",
        "year": 2012,
        "id": "moYUqtRP"
    },
    "gWGWiArf": {
        "authors": [
            {
                "name": "Rui Lin",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials"
            },
            {
                "name": "Lin Zhou",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials"
            },
            {
                "name": "Ke-Long Fang",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials"
            },
            {
                "name": "Yun Lin",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials"
            },
            {
                "name": "Ao Wang",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials"
            },
            {
                "name": "Jia-Hong Zhou",
                "org": "Analysis Testing Center"
            },
            {
                "name": "Shao-Hua Wei",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials"
            }
        ],
        "title": "Characterization and photodynamic activity of a new phthalocyanine nanoparticles",
        "abstract": "Nanoparticles of a hydrophobic photosensitizer, tetrakis (3-trifluoromethylphenoxy) zinc phthalocyanine (FPcZn) have been synthesized by using a simple reprecipitation technique. The resulting drug nanoparticles (FPcZn-NP) were spherical, highly monodispersed and stable in aqueous system, without an additional stabilizer. Comparative studies with FPcZn-NP and FPcZn indicated that after the formation of nanoparticles, FPcZn-NP maintained the efficiency of ",
        "keywords": [
            ""
        ],
        "venue": "Journal of Materials Science: Materials in Medicine",
        "year": 2012,
        "id": "gWGWiArf"
    },
    "GOEZu8B4": {
        "authors": [
            {
                "name": "Bin Huang",
                "org": "Key Laboratory of Organic Synthesis of Jiangsu Province"
            },
            {
                "name": "Yeting Chen",
                "org": "College of Life Science"
            },
            {
                "name": "Qinshu Zhu",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials"
            },
            {
                "name": "Zuhong Lu",
                "org": "School of Biological Science and Medical Engineering"
            },
            {
                "name": "Lin Zhou",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials"
            },
            {
                "name": "Chun Mao",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials"
            },
            {
                "name": "Jian Shen",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials"
            }
        ],
        "title": "Blood compatibility of rambutan-like hybrid nanospheres of Au-F127",
        "abstract": "A study of blood compatibility of rambutan-like hybrid nanospheres of Au-F127 was presented. The rambutan-like hybrid nanospheres of Au-F127 were obtained via self-assembly technique. The blood compatibility of rambutanlike hybrid nanospheres of Au-F127 was characterized in vitro for coagulation tests, plasma recalcification time, complement activation, platelet activation, hemolysis assay and cytotoxicity experiments. The results showed that rambutan-like hybrid nanospheres of Au-F127 exhibited good blood compatibility that strongly depended on the blood compatibility of F127 micells that self-assemblied with the gold nanoparticles. The rambutan-like hybrid nanospheres of Au-F127 provide a promising platform of blood circulation system for early illness diagnosis and therapy with the help of the intriguing aspects of Au nanoparticles including surface plasmon resonance properties, photothermal effect, and the drug-loaded capacity of F127 micelles. \u00a9 2012 American Scientific Publishers. All rights reserved.",
        "keywords": [
            "Au",
            "Blood compatibility",
            "Hybrid nanosphere",
            "Triblock copolymer"
        ],
        "venue": "Advanced Science Letters",
        "year": 2012,
        "id": "GOEZu8B4"
    },
    "bTJaE8LZ": {
        "authors": [
            {
                "name": "Chao Yang",
                "org": "College of Chemistry and Materials Science"
            },
            {
                "name": "Fei Ma",
                "org": "School of Geograph Science"
            },
            {
                "name": "Jing Tang",
                "org": "College of Chemistry and Materials Science"
            },
            {
                "name": "Lina Han",
                "org": "College of Chemistry and Materials Science"
            },
            {
                "name": "Shaohua Wei",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials"
            },
            {
                "name": "Lin Zhou",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials"
            },
            {
                "name": "Jiahong Zhou",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials"
            },
            {
                "name": "Jian Shen",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials"
            },
            {
                "name": "Fang Wang",
                "org": "Analysis and Testing Center"
            }
        ],
        "title": "Synthesis of vanadyl-hypocrellin A complex and its photodynamic properties research",
        "abstract": "Hypocrellin A is an efficient photodynamic agent against many tumor cells and viruses. However, it was found that the preparation of injectable formula for HA was highly hampered by the poor water solubility of these compounds. So, here, a new water-soluble vanadyl-hypocrellin A complex was first synthesized and the complex forming process was studied using spectral and thermal dynamics methods. The results indicated that VO",
        "keywords": [
            "Cytotoxicity",
            "Hypocrellin A",
            "Photodamage",
            "VO2+-HA complex",
            "Water solubility"
        ],
        "venue": "Bioorganic and Medicinal Chemistry Letters",
        "year": 2012,
        "id": "bTJaE8LZ"
    },
    "VAarFgxl": {
        "authors": [
            {
                "name": "Fei Ma",
                "org": "Analysis and Testing Center"
            },
            {
                "name": "Lin Zhou",
                "org": "Analysis and Testing Center"
            },
            {
                "name": "Jing Tang",
                "org": "Analysis and Testing Center"
            },
            {
                "name": "Shaohua Wei",
                "org": "Analysis and Testing Center"
            },
            {
                "name": "Yanhuai Zhou",
                "org": "School of Physics and Technology"
            },
            {
                "name": "Jiahong Zhou",
                "org": "Analysis and Testing Center"
            },
            {
                "name": "Fengbin Wang",
                "org": "Key Laboratory of Analytical Chemistry for Life Science"
            },
            {
                "name": "Jian Shen",
                "org": "Analysis and Testing Center"
            }
        ],
        "title": "A facile method for hemoglobin encapsulation in silica nanoparticles and application in biosensors",
        "abstract": "A facile approach for hemoglobin (Hb) encapsulation in silica nanoparticles (HbSNs) is reported. The results display that the HbSN keeps its structures. The stability of the encapsulated HbSN is significantly increased compared to that of free one at 4 \u00b0C in a buffer of pH 7.4. Moreover, the experiments of HbSN catalytic reduction of H",
        "keywords": [
            "Bioactivity",
            "Electrochemistry",
            "Encapsulation",
            "Hemoglobin-silica nanoparticles (HbSNs)"
        ],
        "venue": "Microporous and Mesoporous Materials",
        "year": 2012,
        "id": "VAarFgxl"
    },
    "lMP7ZCyV": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Jiangsu Key Laboratory Biofunctional Materials, College of Chemistry and Materials Science, Nanjing Normal University"
            },
            {
                "name": "Shaohua Wei",
                "org": "Jiangsu Key Laboratory Biofunctional Materials, College of Chemistry and Materials Science, Nanjing Normal University"
            },
            {
                "name": "Xuefeng Ge",
                "org": "Jiangsu Key Laboratory Biofunctional Materials, College of Chemistry and Materials Science, Nanjing Normal University"
            },
            {
                "name": "Jiahong Zhou",
                "org": "Jiangsu Key Laboratory Biofunctional Materials, College of Chemistry and Materials Science, Nanjing Normal University"
            },
            {
                "name": "Boyang Yu",
                "org": "Department of Complex Prescription of TCM, China Pharmaceutical University"
            },
            {
                "name": "Jian Shen",
                "org": "Jiangsu Key Laboratory Biofunctional Materials, College of Chemistry and Materials Science, Nanjing Normal University"
            }
        ],
        "title": "External heavy-atomic construction of photosensitizer nanoparticles for enhanced in vitro photodynamic therapy of cancer",
        "abstract": "Introduction of heavy atoms around photosensitizers (PSs) generally facilitates intersystem crossing (ISC) and improves their quantum yield of singlet oxygen (",
        "keywords": [
            ""
        ],
        "venue": "Journal of Physical Chemistry B",
        "year": 2012,
        "id": "lMP7ZCyV"
    },
    "2ckznOHo": {
        "authors": [
            {
                "name": "Jing Tang",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials"
            },
            {
                "name": "Chao Yang",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials"
            },
            {
                "name": "Lin Zhou",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials"
            },
            {
                "name": "Fei Ma",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials"
            },
            {
                "name": "Shuchao Liu",
                "org": "College of Life Science"
            },
            {
                "name": "Shaohua Wei",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials"
            },
            {
                "name": "Jiahong Zhou",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials"
            },
            {
                "name": "Yanhuai Zhou",
                "org": "School of Physics and Technology"
            }
        ],
        "title": "Studies on the binding behavior of prodigiosin with bovine hemoglobin by multi-spectroscopic techniques",
        "abstract": "In this article, the interaction mechanism of prodigiosin (PG) with bovine hemoglobin (BHb) is studied in detail using various spectroscopic technologies. UV-vis absorption and fluorescence spectra demonstrate the interaction process. The Stern-Volmer plot and the time-resolved fluorescence study suggest the quenching mechanism of fluorescence of BHb by PG is a static quenching procedure, and the hydrophobic interactions play a major role in binding of PG to BHb. Furthermore, synchronous fluorescence studies, Fourier transform infrared (FTIR) and circular dichroism (CD) spectra reveal that the conformation of BHb is changed after conjugation with PG. \u00a9 2012 Elsevier B.V. All rights reserved.",
        "keywords": [
            "Bovine hemoglobin",
            "Conformational changes",
            "Interaction",
            "Prodigiosin"
        ],
        "venue": "Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy",
        "year": 2012,
        "id": "2ckznOHo"
    },
    "pETpd7op": {
        "authors": [
            {
                "name": "Fei Ma",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials"
            },
            {
                "name": "He-Yong Huang",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials"
            },
            {
                "name": "Lin Zhou",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials"
            },
            {
                "name": "Chao Yang",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials"
            },
            {
                "name": "Jia-Hong Zhou",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials"
            },
            {
                "name": "Zheng-Ming Liu",
                "org": "Testing Center"
            }
        ],
        "title": "Study on the conformation changes of Lysozyme induced by Hypocrellin A: The mechanism investigation",
        "abstract": "The interactions between Lysozyme and Hypocrellin A are investigated in details using time-resolved fluorescence, fourier transform infrared spectroscopy (FTIR), circular dichroism spectroscopy (CD), three-dimensional fluorescence spectra, and thermal gravimetric analysis (TGA) techniques. The results of time-resolved fluorescence suggest that the quenching mechanism is static quenching. FTIR and CD spectroscopy provide evidences of the reducing of \u03b1-helix after interaction. Hypocrellin A could change the micro-environmental of Lysozyme according to hydrophobic interaction between the aromatic ring and the hydrophobic amino acid residues, and the altered polypeptide backbone structures induce the reduction of \u03b1-helical structures. Moreover, TGA study further demonstrates the structure changes of Lysozyme on the effect of Hypocrellin A. This study could provide some important information for the derivatives of HA in pharmacy, pharmacology and biochemistry. \u00a9 2012 Elsevier B.V. All rights reserved.",
        "keywords": [
            "Fourier transform infrared spectroscopy",
            "Hypocrellin A",
            "Lysozyme",
            "Thermal gravimetric analysis",
            "Three-dimensional fluorescence spectra",
            "Time-resolved fluorescence"
        ],
        "venue": "Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy",
        "year": 2012,
        "id": "pETpd7op"
    },
    "K4UgrBXz": {
        "authors": [
            {
                "name": "Ao Wang",
                "org": "College of Chemistry and Materials Science"
            },
            {
                "name": "Li Zhou",
                "org": "College of Chemistry and Materials Science"
            },
            {
                "name": "Kelong Fang",
                "org": "College of Chemistry and Materials Science"
            },
            {
                "name": "Lin Zhou",
                "org": "College of Chemistry and Materials Science"
            },
            {
                "name": "Yun Lin",
                "org": "College of Chemistry and Materials Science"
            },
            {
                "name": "Jiahong Zhou",
                "org": "College of Chemistry and Materials Science"
            },
            {
                "name": "Shaohua Wei",
                "org": "College of Chemistry and Materials Science"
            }
        ],
        "title": "Synthesis of novel octa-cationic and non-ionic 1,2-ethanediamine substituted zinc (II) phthalocyanines and their in vitro anti-cancer activity comparison",
        "keywords": [
            "Photodynamic therapy",
            "Photosensitizer",
            "Phthalocyanine",
            "Singlet oxygen"
        ],
        "venue": "European Journal of Medicinal Chemistry",
        "year": 2012,
        "id": "K4UgrBXz"
    },
    "B0GMvmZa": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "College of Chemistry and Materials Science"
            },
            {
                "name": "Huijun Jiang",
                "org": "School of Pharmacy"
            },
            {
                "name": "Shaohua Wei",
                "org": "College of Chemistry and Materials Science"
            },
            {
                "name": "Xuefeng Ge",
                "org": "College of Chemistry and Materials Science"
            },
            {
                "name": "Jiahong Zhou",
                "org": "College of Chemistry and Materials Science"
            },
            {
                "name": "Jian Shen",
                "org": "College of Chemistry and Materials Science"
            }
        ],
        "title": "High-efficiency loading of hypocrellin B on graphene oxide for photodynamic therapy",
        "abstract": "A novel hybrid of graphene oxide (GO) and hypocrellin B (HB) was prepared using a simple noncovalent method. An efficient loading of HB on GO as high as 2 mg/mg was obtained. Mechanism analysis indicated that the \u03c0-\u03c0 stacking interaction is the dominant driving force in the noncovalent interaction between HB and GO. Irradiation of HB and GO hybrid (HB-GO) results in efficient generation of singlet oxygen ( ",
        "keywords": [
            ""
        ],
        "venue": "Carbon",
        "year": 2012,
        "id": "B0GMvmZa"
    },
    "OSbwTLU1": {
        "authors": [
            {
                "name": "Shan Wu",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Qianjin Wang",
                "org": ""
            },
            {
                "name": "Xuejin Zhang",
                "org": ""
            },
            {
                "name": "Yongyuan Zhu",
                "org": ""
            }
        ],
        "title": "Hybridized effects of plasmonic quadrupolar and dipolar resonances on the perforated planar metallic film",
        "abstract": "We have designed a detuned double-L-shaped nanohole arrays in the metallic film, on which the hybridized plasmonic quadrupolar and dipolar resonance modes can be excited by the incident light, respectively. Compared with the conventional plasmonic resonance modes, the antibonding quadrupolar resonance mode has a higher quality factor due to its lower radiative loss. A quality factor of 38 (theoretical prediction exceeding 100) is obtained in the experiment. \u00a9 2013 IOP Publishing Ltd.",
        "keywords": [
            ""
        ],
        "venue": "Journal of Physics D: Applied Physics",
        "year": 2013,
        "id": "OSbwTLU1"
    },
    "BbU27KwR": {
        "authors": [
            {
                "name": "Chao Yang",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials"
            },
            {
                "name": "Fei Ma",
                "org": "School of Geograph Science"
            },
            {
                "name": "Jing Tang",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials"
            },
            {
                "name": "Lina Han",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials"
            },
            {
                "name": "Shaohua Wei",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials"
            },
            {
                "name": "Lin Zhou",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials"
            },
            {
                "name": "Jiahong Zhou",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials"
            },
            {
                "name": "Jian Shen",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials"
            },
            {
                "name": "Xuefeng Ge",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials"
            }
        ],
        "title": "Comparing the interaction of vanadyl-hypocrellin A complex and hypocrellin A with CT DNA",
        "abstract": "Interaction studies of the vanadyl-hypocrellin A (VO",
        "keywords": [
            "CT DNA",
            "Fluorescence spectroscopy",
            "HA",
            "UV-spectroscopy",
            "VO2+-HA complex",
            "Zeta potential"
        ],
        "venue": "Journal of Molecular Structure",
        "year": 2013,
        "id": "BbU27KwR"
    },
    "gyoOw9Gy": {
        "authors": [
            {
                "name": "Fei Ma",
                "org": "Analysis and Testing Center"
            },
            {
                "name": "Heyong Huang",
                "org": "Analysis and Testing Center"
            },
            {
                "name": "Xuefeng Ge",
                "org": "Analysis and Testing Center"
            },
            {
                "name": "Xiaodi Yang",
                "org": "Analysis and Testing Center"
            },
            {
                "name": "Chao Yang",
                "org": "Analysis and Testing Center"
            },
            {
                "name": "Lina Han",
                "org": "Analysis and Testing Center"
            },
            {
                "name": "Jiahong Zhou",
                "org": "Analysis and Testing Center"
            },
            {
                "name": "Lin Zhou",
                "org": "Analysis and Testing Center"
            }
        ],
        "title": "Complexation of Hypocrellin A with Al3+ in water solution and the photodynamic therapy study",
        "abstract": "The complex of Hypocrellin A with Al",
        "keywords": [
            "Al3+-Hypocrellin A complex",
            "Cytotoxicity",
            "Hypocrellin A",
            "Photodynamic property"
        ],
        "venue": "Bioorganic and Medicinal Chemistry Letters",
        "year": 2013,
        "id": "gyoOw9Gy"
    },
    "VqD3PRQ1": {
        "authors": [
            {
                "name": "Pan Li",
                "org": ""
            },
            {
                "name": "Yu Ding",
                "org": ""
            },
            {
                "name": "Ao Wang",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Shaohua Wei",
                "org": ""
            },
            {
                "name": "Yiming Zhou",
                "org": ""
            },
            {
                "name": "Yawen Tang",
                "org": ""
            },
            {
                "name": "Yu Chen",
                "org": ""
            },
            {
                "name": "Chenxin Cai",
                "org": ""
            },
            {
                "name": "Tianhong Lu",
                "org": ""
            }
        ],
        "title": "Self-assembly of tetrakis (3-trifluoromethylphenoxy) phthalocyaninato cobalt(II) on multiwalled carbon nanotubes and their amperometric sensing application for nitrite",
        "abstract": "In this work, the soluble cobalt phthalocyanine functionalized multiwalled carbon nanotubes (MWCNTs) are synthesized by \u03c0-\u03c0 stacking interaction between tetrakis (3-trifluoromethylphenoxy) phthalocyaninato cobalt(II) (CoPcF) complex and MWCNTs. The physical properties of CoPcF-MWCNTs hybrids are evaluated using spectroscopy (UV-vis, XPS, and Raman) and electron microscopy (TEM and SEM). Subsequently, an amperometric nitrite electrochemical sensor is designed by immobilizing CoPcF-MWCNTs hybrids on the glassy carbon electrode. The immobilized CoPcF complex shows the fast electron transfer rate and excellent electrocatalytic activity for the oxidation of nitrite. Under optimum experimental conditions, the proposed nitrite electrochemical sensor shows the fast response (less than 2 s), wide linear range (9.6 \u00d7 10",
        "keywords": [
            "carbon nanotubes",
            "cobalt phthalocyanine",
            "electrocatalysis",
            "nitrite",
            "sensor"
        ],
        "venue": "ACS Applied Materials and Interfaces",
        "year": 2013,
        "id": "VqD3PRQ1"
    },
    "iIj5hSBY": {
        "authors": [
            {
                "name": "Shan Wu",
                "org": "Department of Physics"
            },
            {
                "name": "Zhao Zhang",
                "org": "National Laboratory of Solid State Microstructures"
            },
            {
                "name": "Yi Zhang",
                "org": "National Laboratory of Solid State Microstructures"
            },
            {
                "name": "Kaiyin Zhang",
                "org": "Department of Physics"
            },
            {
                "name": "Lin Zhou",
                "org": "National Laboratory of Solid State Microstructures"
            },
            {
                "name": "Xuejin Zhang",
                "org": "National Laboratory of Solid State Microstructures"
            },
            {
                "name": "Yongyuan Zhu",
                "org": "National Laboratory of Solid State Microstructures"
            }
        ],
        "title": "Enhanced rotation of the polarization of a light beam transmitted through a silver film with an array of perforated s-shaped holes",
        "abstract": "In this Letter, we realized an enhanced optical rotation of the zero-order transmitted light through a silver film with an array of perforated S-shaped holes. Different from the previous studies, this effect results from the contribution of both the localized surface plasmons and surface plasmon polaritons (SPPs). The rotation angle can be modulated with the thickness due to the phase retardation of the SPPs when tunneling to the emitted surface. With a sample thickness 245 nm, a near-complete cross-polarization conversion (90 optical rotation) can be achieved, representing a major advance in performance compared to the previously reported planar chiral structures. \u00a9 2013 American Physical Society.",
        "keywords": [
            ""
        ],
        "venue": "Physical Review Letters",
        "year": 2013,
        "id": "iIj5hSBY"
    },
    "0QnJaqoO": {
        "authors": [
            {
                "name": "Ao Wang",
                "org": "College of Chemistry and Materials Science"
            },
            {
                "name": "Yanjie Ma",
                "org": "College of Chemistry and Materials Science"
            },
            {
                "name": "Lin Zhou",
                "org": "College of Chemistry and Materials Science"
            },
            {
                "name": "Shan Lu",
                "org": "College of Chemistry and Materials Science"
            },
            {
                "name": "Yun Lin",
                "org": "College of Chemistry and Materials Science"
            },
            {
                "name": "Jiahong Zhou",
                "org": "College of Chemistry and Materials Science"
            },
            {
                "name": "Shaohua Wei",
                "org": "College of Chemistry and Materials Science"
            }
        ],
        "title": "Comparison of two strategies for conferring water solubility to a zinc phthalocyanine substituted with 1,2-diethylamino",
        "abstract": "Polyamines are naturally occurring compounds that play important roles in multiple cell processes. In most cases, phthalocyanine-polyamine (Pc-polyamine) conjugates have good anticancer activity. However, low solubility in water limits their application in photodynamic therapy (PDT). The common method to solve this problem is quaternizing the nitrogen atoms to obtain cationic derivatives. An alternative strategy by preparing hydrochloride is easily neglected. In this paper, a Pc-polyamine conjugate substituted with 1,2-diethylamino (ZnPc1) was conferred water solubility by two different strategies, which are preparing hydrochloride (ZnPc2) and quaternizing the nitrogen atoms (ZnPc3). The synthetic methods and properties of the two derivatives were compared and discussed. Results indicated that both ZnPc2 and ZnPc3 possessed good solubility in water. However, strategy of preparing hydrochloride is much easier than quaternization process and the singlet oxygen generation ability, the photostability and anticancer activity of ZnPc2 in vitro were also superior to the ZnPc3. \u00a9 2013 Elsevier B.V. All rights reserved.",
        "keywords": [
            "Hydrochloride",
            "Photodynamic therapy",
            "Phthalocyanine",
            "Polyamine",
            "Quaternizing",
            "Water solubility"
        ],
        "venue": "Dyes and Pigments",
        "year": 2013,
        "id": "0QnJaqoO"
    },
    "NeTXzGOF": {
        "authors": [
            {
                "name": "Ying-Ying Zhang",
                "org": "School of Physics and Electronic Engineering"
            },
            {
                "name": "Shu-Long Gu",
                "org": "School of Physics and Electronic Engineering"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Physics and Electronic Engineering"
            }
        ],
        "title": "The influence of beam polarization degree on SPR phase sensor",
        "abstract": "The influence of incident beam's polarization degree on the SPR phase sensor is theoretically and experimentally studied in this paper. The results indicate that the decrease of the polarization degree will lead to the phase difference curve's jump decrease near the resonance angle for the ellipsometry method. Besides, the lower the polarization degree, the smaller the jump, which can also lead to reduced sensitivity of the SPR phase sensor. For example, the sensitivity with the polarization degree of 0.9 is 90% that of the polarization degree of 1. \u00a9 (2013) Trans Tech Publications, Switzerland.",
        "keywords": [
            "Polarization degree",
            "SPR sensor",
            "Surface Plasmon resonance"
        ],
        "venue": "Advanced Materials Research",
        "year": 2013,
        "id": "NeTXzGOF"
    },
    "LbrcXH3T": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Jiangsu Key Laboratory Biofunctional Materials"
            },
            {
                "name": "Jihua Liu",
                "org": "Department of Complex Prescription of TCM"
            },
            {
                "name": "Shaohua Wei",
                "org": "Jiangsu Key Laboratory Biofunctional Materials"
            },
            {
                "name": "Xuefeng Ge",
                "org": "Jiangsu Key Laboratory Biofunctional Materials"
            },
            {
                "name": "Jiahong Zhou",
                "org": "Jiangsu Key Laboratory Biofunctional Materials"
            },
            {
                "name": "Boyang Yu",
                "org": "Department of Complex Prescription of TCM"
            },
            {
                "name": "Jian Shen",
                "org": "Jiangsu Key Laboratory Biofunctional Materials"
            }
        ],
        "title": "A facile drug delivery system preparation through the interaction between drug and iron ion of transferrin",
        "abstract": "Many anticancer drugs have the capability to form stable complex with metal ions. Based on such property, a simple method to combine these drugs with transferrin, through the interaction between drug and Fe ion of transferrin, to improve their anticancer activity, is proposed. To demonstrate this technique, the complex of photosensitive anticancer drug hypocrellin A and transferrin was prepared by such facile method. The results indicated that the complex of hypocrellin A and transferrin can stabilize in aqueous solution. In vitro studies have demonstrated the superior cancer cell uptake ability of hypocrellin A-transferrin complex to the free hypocrellin A. Significant damage to such drug-impregnated tumor cells was observed upon irradiation and the cancer cells killing ability of hypocrellin A-transferrin was stronger than the free hypocrellin A within a certain range of concentrations. The above results demonstrated the validity and potential of our proposed strategy to prepare the drug delivery system of this type of anti-cancer drugs and transferrin. \u00a9 2013 Springer Science+Business Media.",
        "keywords": [
            "Cancer",
            "Drug delivery",
            "Hypocrellin A",
            "Iron",
            "Transferrin"
        ],
        "venue": "Journal of Nanoparticle Research",
        "year": 2013,
        "id": "LbrcXH3T"
    },
    "aYaLdrd0": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Jiangsu Key Laboratory Biofunctional Materials"
            },
            {
                "name": "Xuefeng Ge",
                "org": "Jiangsu Key Laboratory Biofunctional Materials"
            },
            {
                "name": "Jihua Liu",
                "org": "State Key Laboratory of Natural Medicines"
            },
            {
                "name": "Jiahong Zhou",
                "org": "Jiangsu Key Laboratory Biofunctional Materials"
            },
            {
                "name": "Shaohua Wei",
                "org": "Jiangsu Key Laboratory Biofunctional Materials"
            },
            {
                "name": "Fuyou Li",
                "org": "Department of Chemistry"
            },
            {
                "name": "Jian Shen",
                "org": "Jiangsu Key Laboratory Biofunctional Materials"
            }
        ],
        "title": "Internal heavy atom effect of Au(III) and Pt(IV) on hypocrellin A for enhanced in vitro photodynamic therapy of cancer",
        "abstract": "Hypocrellin A (HA), an a natural perylene quinine photosensitizers (PSs), can chelate with heavy metal ions, including Au(III) and Pt(IV), to form a 1:2 complex, which exhibits enhanced ",
        "keywords": [
            "Anticancer activity",
            "Complex",
            "Hypocrellin A",
            "Internal heavy atom effect",
            "Intersystem crossing"
        ],
        "venue": "Bioorganic and Medicinal Chemistry Letters",
        "year": 2013,
        "id": "aYaLdrd0"
    },
    "hHZcDS3L": {
        "authors": [
            {
                "name": "Tianhui Wang",
                "org": "College of Chemistry and Materials Science"
            },
            {
                "name": "Ao Wang",
                "org": "College of Chemistry and Materials Science"
            },
            {
                "name": "Lin Zhou",
                "org": "College of Chemistry and Materials Science"
            },
            {
                "name": "Shan Lu",
                "org": "College of Chemistry and Materials Science"
            },
            {
                "name": "Weiwei Jiang",
                "org": "College of Chemistry and Materials Science"
            },
            {
                "name": "Yun Lin",
                "org": "College of Chemistry and Materials Science"
            },
            {
                "name": "Jiahong Zhou",
                "org": "College of Chemistry and Materials Science"
            },
            {
                "name": "Shaohua Wei",
                "org": "College of Chemistry and Materials Science"
            }
        ],
        "title": "Synthesis of a novel water-soluble zinc phthalocyanine and its CT DNA-damaging studies",
        "abstract": "A novel 3-(4-methoxybenzylamino) propanoic acid substituted water-soluble zinc phthalocyanine (CNPcZn) was synthesized. The interaction between CNPcZn with calf thymus DNA (CT DNA) was studied using spectroscopic methods. The studies indicated that CNPcZn has strong affinity to CT DNA, and furthermore, CNZnPc showed excellent photodamaging activity to CT DNA. Above results indicated that such CNPcZn has great potential to be used as an effective photosensitizer in the field of photodynamic therapy. \u00a9 2013 Elsevier B.V. All rights reserved.",
        "keywords": [
            "CT DNA",
            "Photodynamic therapy",
            "Phthalocyanine",
            "Singlet oxygen",
            "Water-soluble"
        ],
        "venue": "Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy",
        "year": 2013,
        "id": "hHZcDS3L"
    },
    "yI1619tW": {
        "authors": [
            {
                "name": "Ao Wang",
                "org": "Jiangsu Key Laboratory of Biomedical Materials, School of Chemistry and Materials Science, Nanjing Normal University"
            },
            {
                "name": "Yanjie Ma",
                "org": "Jiangsu Key Laboratory of Biomedical Materials, School of Chemistry and Materials Science, Nanjing Normal University"
            },
            {
                "name": "Yi Wang",
                "org": "Jiangsu Key Laboratory of Biomedical Materials, School of Chemistry and Materials Science, Nanjing Normal University"
            },
            {
                "name": "Shan Lu",
                "org": "Jiangsu Key Laboratory of Biomedical Materials, School of Chemistry and Materials Science, Nanjing Normal University"
            },
            {
                "name": "Yun Lin",
                "org": "Jiangsu Key Laboratory of Biomedical Materials, School of Chemistry and Materials Science, Nanjing Normal University"
            },
            {
                "name": "Jiahong Zhou",
                "org": "Jiangsu Key Laboratory of Biomedical Materials, School of Chemistry and Materials Science, Nanjing Normal University"
            },
            {
                "name": "Lin Zhou",
                "org": "Jiangsu Key Laboratory of Biomedical Materials, School of Chemistry and Materials Science, Nanjing Normal University"
            },
            {
                "name": "Shaohua Wei",
                "org": "Jiangsu Key Laboratory of Biomedical Materials, School of Chemistry and Materials Science, Nanjing Normal University"
            }
        ],
        "title": "Effects of protonation degree on photodynamic activity of zinc phthalocyanine substituted with 1,2-diethylamino",
        "abstract": "This work reports on the effects of protonation degree on the photodynamic activity of zinc phthalocyanine substituted with 1,2-diethylamino (ZnPc1). Photophysical properties, singlet oxygen generation ability and photodynamic anticancer activity of derivatives of ZnPc1 with different protonation degree were studied and compared. Results indicated that the protonation degree can greatly influence the photophysical and photochemical properties of ZnPc1, thereby affecting its photodynamic activity. When the mole ratio of ZnPc1 and hydrochloric acid (HCl) was 1:8, the derivative of ZnPc1 showed the best photodynamic activity.",
        "keywords": [
            "Photodynamic activity",
            "Photosensitizer",
            "Phthalocyanine",
            "Protonation degree",
            "Singlet oxygen"
        ],
        "venue": "Inorganic Chemistry Communications",
        "year": 2014,
        "id": "yI1619tW"
    },
    "4cULt2r2": {
        "authors": [
            {
                "name": "Wenli Xie",
                "org": "College of Chemistry and Materials Science, Jiangsu Key Laboratory Biofunctional Materials, Nanjing Normal University"
            },
            {
                "name": "Shaohua Wei",
                "org": "College of Chemistry and Materials Science, Jiangsu Key Laboratory Biofunctional Materials, Nanjing Normal University"
            },
            {
                "name": "Jihua Liu",
                "org": "State Key Laboratory of Natural Medicines, Department of Complex Prescription of TCM, China Pharmaceutical University"
            },
            {
                "name": "Xuefeng Ge",
                "org": "College of Chemistry and Materials Science, Jiangsu Key Laboratory Biofunctional Materials, Nanjing Normal University"
            },
            {
                "name": "Lin Zhou",
                "org": "College of Chemistry and Materials Science, Jiangsu Key Laboratory Biofunctional Materials, Nanjing Normal University"
            },
            {
                "name": "Jiahong Zhou",
                "org": "College of Chemistry and Materials Science, Jiangsu Key Laboratory Biofunctional Materials, Nanjing Normal University"
            },
            {
                "name": "Jian Shen",
                "org": "College of Chemistry and Materials Science, Jiangsu Key Laboratory Biofunctional Materials, Nanjing Normal University"
            }
        ],
        "title": "Spectroscopic studies on the interaction of Ga3+-hypocrellin A with myoglobin",
        "abstract": "In this article, the interaction mechanism of Ga",
        "keywords": [
            "Circular dichroism spectroscopy",
            "Myoglobin",
            "Steady state fluorescence spectroscopy",
            "Time-resolved fluorescence spectroscopy",
            "UV-vis absorption spectroscopy"
        ],
        "venue": "Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy",
        "year": 2014,
        "id": "4cULt2r2"
    },
    "RGA1ki45": {
        "authors": [
            {
                "name": "Wenli Xie",
                "org": "College of Chemistry and Materials Science"
            },
            {
                "name": "Shaohua Wei",
                "org": "College of Chemistry and Materials Science"
            },
            {
                "name": "Jihua Liu",
                "org": "State Key Laboratory of Natural Medicines"
            },
            {
                "name": "Xuefeng Ge",
                "org": "College of Chemistry and Materials Science"
            },
            {
                "name": "Lin Zhou",
                "org": "College of Chemistry and Materials Science"
            },
            {
                "name": "Jiahong Zhou",
                "org": "College of Chemistry and Materials Science"
            },
            {
                "name": "Jian Shen",
                "org": "College of Chemistry and Materials Science"
            }
        ],
        "title": "Combination anticancer therapy activity studies for the complex of hypocrellin A and gallium ion",
        "abstract": "Combining different treatment modalities is widely employed in oncology to improve the therapeutic response. In this work, we develop a multifunctional complex for co-delivery of the anticancer drug Ga(NO",
        "keywords": [
            "Anticancer",
            "Combination therapy",
            "Complex",
            "Gallium ion",
            "Hypocrellin A",
            "Photodynamic therapy"
        ],
        "venue": "Dyes and Pigments",
        "year": 2014,
        "id": "RGA1ki45"
    },
    "aNMxqwMV": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "School of Physics and Electronic Engineering"
            },
            {
                "name": "Xiaoqiang Yu",
                "org": "Department of Physics"
            },
            {
                "name": "Jia Zhu",
                "org": "College of Engineering and Applied Sciences"
            }
        ],
        "title": "Metal-core/semiconductor-shell nanocones for broadband solar absorption enhancement",
        "abstract": "Nanostructure-based photovoltaic devices have exhibited several advantages, such as reduced reflection, extraordinary light trapping, and so forth. In particular, semiconductor nanostructures provide optical modes that have strong dependence on the size and geometry. Metallic nanostructures also attract a lot of attention because of the appealing plasmonic effect on the near-field enhancement. In this study, we propose a novel design, the metal-core/ semiconductor-shell nanocones with the core radius varying in a linearly gradient style. With a thin layer of semiconductor absorber coated on a metallic cone, such a design can lead to significant and broadband absorption enhancement across the entire visible and near-infrared solar spectrum. As an example of demonstration, a layer of 16 nm thick crystalline silicon (c-Si) coated on a silver nanocone can absorb 27% of standard solar radiation across a broad spectral range of 300-1100 nm, which is equivalent to a 700 nm thick flat c-Si film. Therefore, the absorption enhancement factor approaching the Yablonovitch limit is achieved with this design. The significant absorption enhancement can be ascribed to three types of optical modes, that is, Fabry-Perot modes, plasmonic modes, and hybrid modes that combine the features of the previous two. In addition, the unique nanocone geometry enables the linearly gradient radius of the semiconductor shell, which can support multiple optical resonances, critical for the broadband absorption. Our design may find general usage as elements for the low cost, high efficiency solar conversion and water-splitting devices. \u00a9 2014 American Chemical Society.",
        "keywords": [
            "broadband absorption",
            "core-shell",
            "nanocone",
            "plasmonic",
            "Si",
            "Solar cell"
        ],
        "venue": "Nano Letters",
        "year": 2014,
        "id": "aNMxqwMV"
    },
    "kNlNwmQh": {
        "authors": [
            {
                "name": "Lina Han",
                "org": "Jiangsu Collaborative Innovation Center of Biomedical Functional Materials"
            },
            {
                "name": "Yanhuai Zhou",
                "org": "Department of Physical Science and Technology"
            },
            {
                "name": "Xiaoqin Huang",
                "org": "Department of Physical Science and Technology"
            },
            {
                "name": "Mengsi Xiao",
                "org": "Jiangsu Collaborative Innovation Center of Biomedical Functional Materials"
            },
            {
                "name": "Lin Zhou",
                "org": "Jiangsu Collaborative Innovation Center of Biomedical Functional Materials"
            },
            {
                "name": "Jiahong Zhou",
                "org": "Jiangsu Collaborative Innovation Center of Biomedical Functional Materials"
            },
            {
                "name": "Aihong Wang",
                "org": "Nursing College of Nanjing University of Chinese Medicine"
            },
            {
                "name": "Jian Shen",
                "org": "Jiangsu Collaborative Innovation Center of Biomedical Functional Materials"
            }
        ],
        "title": "A multi-spectroscopic approach to investigate the interaction of prodigiosin with ct-DNA",
        "abstract": "The interaction between prodigiosin (PG) and calf thymus DNA (ct-DNA) was investigated firstly by using UV-Visible (UV-Vis), fluorescence, Fourier transform infrared (FT-IR), circular dichroism (CD) spectroscopies and viscosity measurement in Tris-HCl buffer solution (pH 6.8). The experimental results indicated that PG intercalated into the DNA helix. Upon addition of ct-DNA, PG showed hypochromic effect and slight redshift in the absorption spectra, and the melting temperature of ct-DNA was increased by from 58 to 64 C. Furthermore, FT-IR spectrum and CD spectra also suggested that the partial bases of ct-DNA react with prodigiosin. The fluorescence quenching mechanism was studied using ethidium bromide as a DNA probe, The binding constants of PG with ct-DNA in the presence of EB are 4.46 \u00d7 10",
        "keywords": [
            "Ct-DNA",
            "Ethidium bromide (EB)",
            "Fluorescence quenching",
            "Intercalation",
            "Prodigiosin"
        ],
        "venue": "Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy",
        "year": 2014,
        "id": "kNlNwmQh"
    },
    "XIR9PT8T": {
        "authors": [
            {
                "name": "Mengsi Xiao",
                "org": "Jiangsu Key Laboratory of Biomedical Materials"
            },
            {
                "name": "Lina Han",
                "org": "Jiangsu Key Laboratory of Biomedical Materials"
            },
            {
                "name": "Lin Zhou",
                "org": "Jiangsu Key Laboratory of Biomedical Materials"
            },
            {
                "name": "Yanhuai Zhou",
                "org": "Department of Physical Science and Technology"
            },
            {
                "name": "Xiaoqin Huang",
                "org": "Department of Physical Science and Technology"
            },
            {
                "name": "Xuefeng Ge",
                "org": "Jiangsu Key Laboratory of Biomedical Materials"
            },
            {
                "name": "Shaohua Wei",
                "org": "Jiangsu Key Laboratory of Biomedical Materials"
            },
            {
                "name": "Jiahong Zhou",
                "org": "Jiangsu Key Laboratory of Biomedical Materials"
            },
            {
                "name": "Heming Wu",
                "org": "Institute of Stomatology"
            },
            {
                "name": "Jian Shen",
                "org": "Jiangsu Key Laboratory of Biomedical Materials"
            }
        ],
        "title": "Comparison and investigation of bovine hemoglobin binding to dihydroartemisinin and 9-hydroxy-dihydroartemisinin: Spectroscopic characterization",
        "abstract": "The UV-vis absorption, steady state/time resolved fluorescence spectroscopy and synchronous fluorescence, circular dichroism (CD) spectroscopy are used to investigate the interaction mechanisms of dihydroartemisinin (DHA) and 9-hydroxy-dihydroartemisinin (9-OH DHA), respectively. The UV-vis studies present that DHA and 9-OH DHA can disturb the structure of bovine hemoglobin (BHb). Steady state/time resolved and synchronous fluorescence spectroscopy reveal that the binding constant of DHA with BHb is bigger than 9-OH DHA. CD spectra indicate DHA and 9-OH DHA can change the conformation of BHb. The comparison results suggest that the binding of BHb with DHA is more stable and stronger than 9-OH DHA. \u00a9 2014 Published by Elsevier B.V.",
        "keywords": [
            "9-OH DHA",
            "Bovine hemoglobin",
            "Comparison",
            "DHA",
            "Spectroscopic characterization"
        ],
        "venue": "Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy",
        "year": 2014,
        "id": "XIR9PT8T"
    },
    "cKgXSiYW": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "College of Chemistry and Materials Science, Jiangsu Key Laboratory Biofunctional Materials, Nanjing Normal University"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Chemistry and Chemical Engineering, Jiangsu University"
            },
            {
                "name": "Shaohua Wei",
                "org": "College of Chemistry and Materials Science, Jiangsu Key Laboratory Biofunctional Materials, Nanjing Normal University"
            },
            {
                "name": "Xuefeng Ge",
                "org": "College of Chemistry and Materials Science, Jiangsu Key Laboratory Biofunctional Materials, Nanjing Normal University"
            },
            {
                "name": "Jiahong Zhou",
                "org": "College of Chemistry and Materials Science, Jiangsu Key Laboratory Biofunctional Materials, Nanjing Normal University"
            },
            {
                "name": "Huijun Jiang",
                "org": "School of Pharmacy, Nanjing Medical University"
            },
            {
                "name": "Fuyou Li",
                "org": "Department of Chemistry, State Key Laboratory of Molecular Engineering of Polymers, Institutes Fudan University"
            },
            {
                "name": "Jian Shen",
                "org": "College of Chemistry and Materials Science, Jiangsu Key Laboratory Biofunctional Materials, Nanjing Normal University"
            }
        ],
        "title": "Combination of chemotherapy and photodynamic therapy using graphene oxide as drug delivery system",
        "abstract": "Previous research indicated that graphene oxide (GO) can be used to deliver photosensitive anticancer drug, Hypocrellin A (HA), in photodynamic therapy (PDT). However, the anticancer activity of HA was obviously decreased after been loaded on GO. To solve this problem, a chemotherapy drug, 7-ethyl-10- hydroxycamptothecin (SN-38), was co-loaded on the HA loaded GO (HA/SN-38/GO) as a multimodal carrier for the synergistic combination of PDT and chemotherapy for cancer. In vitro results showed that the combination therapy exhibited a synergistic antiproliferative effect compared with PDT and chemotherapy alone. Therefore, HA/SN-38/GO delivery system has the potential to offer dual therapies for the synergistic combination of PDT and chemotherapy for the treatment of cancer. \u00a9 2014 Elsevier B.V. All rights reserved.",
        "keywords": [
            "7-Ethyl-10-hydroxycamptothecin",
            "Combination therapy",
            "Graphene oxide",
            "Hypocrellin A"
        ],
        "venue": "Journal of Photochemistry and Photobiology B: Biology",
        "year": 2014,
        "id": "cKgXSiYW"
    },
    "8j9LSszI": {
        "authors": [
            {
                "name": "Chao Yang",
                "org": ""
            },
            {
                "name": "Lina Han",
                "org": ""
            },
            {
                "name": "Fei Ma",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Jiahong Zhou",
                "org": ""
            },
            {
                "name": "Shaohua Wei",
                "org": ""
            },
            {
                "name": "Guiqin Huang",
                "org": ""
            },
            {
                "name": "Jian Shen",
                "org": ""
            },
            {
                "name": "Fuyou Li",
                "org": ""
            }
        ],
        "title": "Synthesis of calcium phosphate nanoparticle-based docetaxel delivery system and its in vitro anticancer activity",
        "abstract": "A new docetaxel (DTX) delivery system has been prepared based on calcium phosphate nanoparticles (CaP NPs) and obtained DTX-adsorbed CaP NPs. The DTX-adsorbed CaP NPs were nearly spherical with mean diameter about 200 nm and a negative zeta potential of -18.8 \u00b1 0.5 mV. They can be well dispersed and stable in water for a long time. In addition, the DTX-adsorbed CaP NPs showed higher cytotoxicity in human nonsmall-cell lung cancer (NSCLC) cell lines than that of DTX at the same experimental conditions. Thus, it could be concluded that CaP NPs can be a promising DTX delivery vehicle in NSCLC chemotherapy.",
        "keywords": [
            ""
        ],
        "venue": "International Journal of Applied Ceramic Technology",
        "year": 2015,
        "id": "8j9LSszI"
    },
    "4EDRyphd": {
        "authors": [
            {
                "name": "Liu Zhang",
                "org": "School of Chemistry and Materials Science, Key Laboratory of Applied Photochemistry, Nanjing Normal University"
            },
            {
                "name": "Ao Wang",
                "org": "School of Chemistry and Materials Science, Key Laboratory of Applied Photochemistry, Nanjing Normal University"
            },
            {
                "name": "Shan Lu",
                "org": "School of Chemistry and Materials Science, Key Laboratory of Applied Photochemistry, Nanjing Normal University"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Chemistry and Materials Science, Key Laboratory of Applied Photochemistry, Nanjing Normal University"
            },
            {
                "name": "Jiahong Zhou",
                "org": "School of Chemistry and Materials Science, Key Laboratory of Applied Photochemistry, Nanjing Normal University"
            },
            {
                "name": "Yun Lin",
                "org": "School of Chemistry and Materials Science, Key Laboratory of Applied Photochemistry, Nanjing Normal University"
            },
            {
                "name": "Shaohua Wei",
                "org": "School of Chemistry and Materials Science, Key Laboratory of Applied Photochemistry, Nanjing Normal University"
            }
        ],
        "title": "The influences of the number of the ammonium groups and their arrangement manner on the photophysical properties of the quaternized zinc phthalocyanines",
        "abstract": "The influences of the number of the ammonium groups and their arrangement manner on the photophysical properties of the quaternized zinc phthalocyanines were studied. The aggregation tendency, singlet oxygen generation ability and the fluorescence intensity properties of the quaternized zinc phthalocyanines were studied and compared. Results indicated that more quaternized ammonium groups and the straight chain arrangement manner for the quaternized zinc phthalocyanines can decrease aggregation degree and increase singlet oxygen generation and fluorescence intensity.",
        "keywords": [
            "Fluorescence intensity",
            "Molecular configuration",
            "Photodynamic therapy",
            "Phthalocyanine",
            "Quaternized nitrogen number",
            "Singlet oxygen generation"
        ],
        "venue": "Inorganic Chemistry Communications",
        "year": 2015,
        "id": "4EDRyphd"
    },
    "PE7dINA1": {
        "authors": [
            {
                "name": "Mengsi Xiao",
                "org": "Jiangsu Key Laboratory of Biomedical Materials, College of Chemistry and Materials Science, Nanjing Normal University"
            },
            {
                "name": "Xiuxue Yuan",
                "org": "Jiangsu Key Laboratory of Biomedical Materials, College of Chemistry and Materials Science, Nanjing Normal University"
            },
            {
                "name": "Wenli Xie",
                "org": "Jiangsu Key Laboratory of Biomedical Materials, College of Chemistry and Materials Science, Nanjing Normal University"
            },
            {
                "name": "Xuefeng Ge",
                "org": "Jiangsu Key Laboratory of Biomedical Materials, College of Chemistry and Materials Science, Nanjing Normal University"
            },
            {
                "name": "Yanhuai Zhou",
                "org": "Department of Physical Science and Technology, Nanjing Normal University"
            },
            {
                "name": "Lin Zhou",
                "org": "Jiangsu Key Laboratory of Biomedical Materials, College of Chemistry and Materials Science, Nanjing Normal University"
            },
            {
                "name": "Jiahong Zhou",
                "org": "Jiangsu Key Laboratory of Biomedical Materials, College of Chemistry and Materials Science, Nanjing Normal University"
            },
            {
                "name": "Jian Shen",
                "org": "Jiangsu Key Laboratory of Biomedical Materials, College of Chemistry and Materials Science, Nanjing Normal University"
            }
        ],
        "title": "Comparison of 9-hydroxy-artemisinin with artemisinin: Interaction with bovine hemoglobin",
        "abstract": "In this article, the UV-vis absorption, steady state/time resolved fluorescence spectroscopy and synchronous fluorescence, circular dichrosim (CD) spectroscopy are used to investigate the interaction of artemisinin (QHS) and 9-hydroxy-artemisinin (9-OH QHS) with BHb, respectively. The UV-vis studies present that QHS and 9-OH QHS can disturb the structure of bovine hemoglobin (BHb). Fluorescence data presents that the binding constant of QHS and 9-OH QHS with BHb complex at 298 K is 4.32\u00d710",
        "keywords": [
            "9-hydroxy-artemisinin",
            "Artemisinin",
            "Bovine hemoglobin",
            "CD spectroscopy",
            "Fluorescence spectroscopy",
            "UV-vis"
        ],
        "venue": "Journal of Luminescence",
        "year": 2015,
        "id": "PE7dINA1"
    },
    "JHwiYzVj": {
        "authors": [
            {
                "name": "Xiuxue Yuan",
                "org": "College of Chemistry and Materials Science, Key Laboratory of Applied Photochemistry, Nanjing Normal University"
            },
            {
                "name": "Wenchao Gu",
                "org": "College of Chemistry and Materials Science, Key Laboratory of Applied Photochemistry, Nanjing Normal University"
            },
            {
                "name": "Mengsi Xiao",
                "org": "College of Chemistry and Materials Science, Key Laboratory of Applied Photochemistry, Nanjing Normal University"
            },
            {
                "name": "Wenli Xie",
                "org": "College of Chemistry and Materials Science, Key Laboratory of Applied Photochemistry, Nanjing Normal University"
            },
            {
                "name": "Shaohua Wei",
                "org": "College of Chemistry and Materials Science, Key Laboratory of Applied Photochemistry, Nanjing Normal University"
            },
            {
                "name": "Lin Zhou",
                "org": "College of Chemistry and Materials Science, Key Laboratory of Applied Photochemistry, Nanjing Normal University"
            },
            {
                "name": "Jiahong Zhou",
                "org": "College of Chemistry and Materials Science, Key Laboratory of Applied Photochemistry, Nanjing Normal University"
            },
            {
                "name": "Jian Shen",
                "org": "College of Chemistry and Materials Science, Key Laboratory of Applied Photochemistry, Nanjing Normal University"
            }
        ],
        "title": "Interactions of CT DNA with hexagonal NaYF",
        "abstract": "The interaction of UCPs with CT DNA are studied in detail by zeta potential, Energy dispersive spectrometer (EDS) spectroscopy, Thermogravimetric (TGA) analysis, DNA melting determination and various spectroscopic techniques including Ultraviolet-Visible (UV-Vis) absorption, fluorescence, circular dichroism (CD), Fourier transform infrared (FTIR) and Raman spectroscopy. The results indicate that CT DNA can assemble on the surface of UCPs mainly by relative stronger hydrophobic force and electrostatic binding, and the predominant interaction site is the deoxyribosyl phosphate backbone of CT DNA. Moreover, after interacting with UCPs, the double helix structure of DNA is undamaged.",
        "keywords": [
            "Complex",
            "CT DNA",
            "Deoxyribosyl phosphate backbone",
            "Electrostatic binding",
            "Hydrophobic force",
            "UCPs"
        ],
        "venue": "Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy",
        "year": 2015,
        "id": "JHwiYzVj"
    },
    "P1Qu5VWw": {
        "authors": [
            {
                "name": "Enyi Chen",
                "org": "College of Chemistry and Materials Science, Key Laboratory of Applied Photochemistry, Nanjing Normal University"
            },
            {
                "name": "Xiaoli Mo",
                "org": "College of Life Science, Nanjing Normal University"
            },
            {
                "name": "Xuefeng Ge",
                "org": "College of Chemistry and Materials Science, Key Laboratory of Applied Photochemistry, Nanjing Normal University"
            },
            {
                "name": "Ao Wang",
                "org": "College of Chemistry and Materials Science, Key Laboratory of Applied Photochemistry, Nanjing Normal University"
            },
            {
                "name": "Shaohua Wei",
                "org": "College of Chemistry and Materials Science, Key Laboratory of Applied Photochemistry, Nanjing Normal University"
            },
            {
                "name": "Lin Zhou",
                "org": "College of Chemistry and Materials Science, Key Laboratory of Applied Photochemistry, Nanjing Normal University"
            },
            {
                "name": "Jiahong Zhou",
                "org": "College of Chemistry and Materials Science, Key Laboratory of Applied Photochemistry, Nanjing Normal University"
            },
            {
                "name": "Jian Shen",
                "org": "College of Chemistry and Materials Science, Key Laboratory of Applied Photochemistry, Nanjing Normal University"
            }
        ],
        "title": "Preparation and in vitro anticancer activity comparison of photosensitive nanoparticles with different self-assemble degree",
        "abstract": "Abstract Self-assembled organic photosensitive nanoparticles have been widely used in diagnosis and therapeutic of cancer. In this manuscript, a simple but effective method to regulate the self-assemble degree of small charge photosensitive drug was demonstrated. Studies indicated that the ordered self-assembled nanostructures with proper assemble degree can significantly enhances the reactive oxygen species generation efficiency and, thereby, improve the in vitro photodynamic efficacy comparing with the corresponding monomers.",
        "keywords": [
            "Anticancer",
            "Hypocrellin A",
            "Ion strength",
            "Photodynamic therapy",
            "Reactive oxygen species",
            "Self-assemble degree"
        ],
        "venue": "Dyes and Pigments",
        "year": 2015,
        "id": "P1Qu5VWw"
    },
    "U89K7XIQ": {
        "authors": [
            {
                "name": "Dongmei Lin",
                "org": "College of Chemistry and Materials Science, Jiangsu Key Laboratory of Biofunctional Materials, Nanjing Normal University"
            },
            {
                "name": "Yue Wang",
                "org": "College of Chemistry and Materials Science, Jiangsu Key Laboratory of Biofunctional Materials, Nanjing Normal University"
            },
            {
                "name": "Quanquan Zhang",
                "org": "College of Chemistry and Materials Science, Jiangsu Key Laboratory of Biofunctional Materials, Nanjing Normal University"
            },
            {
                "name": "Jiahong Zhou",
                "org": "College of Chemistry and Materials Science, Jiangsu Key Laboratory of Biofunctional Materials, Nanjing Normal University"
            },
            {
                "name": "Lin Zhou",
                "org": "College of Chemistry and Materials Science, Jiangsu Key Laboratory of Biofunctional Materials, Nanjing Normal University"
            },
            {
                "name": "Shaohua Wei",
                "org": "College of Chemistry and Materials Science, Jiangsu Key Laboratory of Biofunctional Materials, Nanjing Normal University"
            }
        ],
        "title": "The substituted amino group type dependent sensitivity enhancing of cationic phthalocyanine derivatives for photodynamic activity",
        "abstract": "Many reports indicated that the cellular uptaken and photodynamic anti-cancer activity of amino group modified phthalocyanine (Pc) could be greatly improved in the acid environment around cancer cells because such Pc could transfer to their hydrochloride protonated form and inhibit the intramolecular photoinduced electron transfer (PET) effect. However, no more researches are carried out to indicate whether this law has the extensive applicability in all kinds of amino modified Phthalocyanines (Pcs). So, here, four amino groups modified Pcs and their hydrochloride or quaternized cationic derivatives, with two kinds of amino groups (phenylamine and benzylamine) substituted were synthesized. Their solubility in aqueous system, cancer cell uptaken ability and photodynamic activities were also systematically compared. Our research results indicated that above law had the extensive applicability in benzylamine amino groups modified Pcs. But for phenylamine amino groups modified ones, the cancer cell uptaken ability and anti-cancer activity of hydrochloride derivatives were obviously decreased comparing with the unmodified Pc because its nitrogen atom was closer to the Pc ring, which would induce its nitrogen atom and the ring to form p-\u03c0 conjugation system, furthermore, the relatively free state of lone pair electrons of surrounding nitrogen atom leaded to PET strengthening.",
        "keywords": [
            "Benzylamine",
            "Hydrochloride",
            "Phenylamine",
            "Photodynamic therapy",
            "Phthalocyanine",
            "Quaternization"
        ],
        "venue": "Journal of Photochemistry and Photobiology A: Chemistry",
        "year": 2016,
        "id": "U89K7XIQ"
    },
    "6zqcEbpS": {
        "authors": [
            {
                "name": "Wei Li",
                "org": "Key Laboratory of Photo-electronics Thin Film Devices and Technique of Tianjin"
            },
            {
                "name": "Yun Sun",
                "org": "Institute of Photo-electronics Thin Film Devices and Technique"
            },
            {
                "name": "Wei Liu",
                "org": "Institute of Photo-electronics Thin Film Devices and Technique"
            },
            {
                "name": "Feng-Yan Li",
                "org": "Institute of Photo-electronics Thin Film Devices and Technique"
            },
            {
                "name": "Lin Zhou",
                "org": "Institute of Photo-electronics Thin Film Devices and Technique"
            }
        ],
        "title": "Effects of proportion and distribution of gallium on quantum efficiency of CIGS thin film solar cell",
        "abstract": "The CIGS thin films were deposited by the two-step growth process using sputtering and selenization system on Mo-coated soda lime glass substrates. The solid selenium was used as Se source instead of H",
        "keywords": [
            "CIGS solar cell",
            "Gallium grading",
            "Quantum efficiency",
            "Selenization"
        ],
        "venue": "Rengong Jingti Xuebao/Journal of Synthetic Crystals",
        "year": 2006,
        "id": "6zqcEbpS"
    },
    "7luO4oA5": {
        "authors": [
            {
                "name": "Wei Li",
                "org": ""
            },
            {
                "name": "Yun Sun",
                "org": ""
            },
            {
                "name": "Wei Liu",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            }
        ],
        "title": "Fabrication of Cu(In,Ga)Se",
        "abstract": "CIGS films were prepared on Mo-coated glass by sputtering and selenization processes. The metallic precursors were selenized under higher pressure in selenium vapor instead of H",
        "keywords": [
            "CIGS solar cell",
            "Selenization",
            "Solid Se source"
        ],
        "venue": "Solar Energy",
        "year": 2006,
        "id": "7luO4oA5"
    },
    "kuItcKQB": {
        "authors": [
            {
                "name": "Wei Li",
                "org": "Institute of Photoelectron"
            },
            {
                "name": "Yun Sun",
                "org": "Institute of Photoelectron"
            },
            {
                "name": "Wei Liu",
                "org": "Institute of Photoelectron"
            },
            {
                "name": "Feng-Yan Li",
                "org": "Institute of Photoelectron"
            },
            {
                "name": "Lin Zhou",
                "org": "Institute of Photoelectron"
            }
        ],
        "title": "Improvement in efficiency of solar cell by removing Cu",
        "abstract": "CIGS thin films are deposited by sputtering and selenization. The synthesis of semiconducting polycrystalline thin films and characteristics of devices based on the CIGS absorbing layers are investigated. Their microstructures are characterized by x-ray diffraction and Raman spectroscopy. The results reveal that there exist metallic Cu",
        "keywords": [
            "CIGS thin films",
            "Cu2-xSe",
            "Optimization of temperature profile"
        ],
        "venue": "Chinese Physics",
        "year": 2006,
        "id": "kuItcKQB"
    },
    "ZaLBCNYv": {
        "authors": [
            {
                "name": "Chuan-Ming Xu",
                "org": "Institute of Photoelectronics"
            },
            {
                "name": "Yun Sun",
                "org": "Institute of Photoelectronics"
            },
            {
                "name": "Lin Zhou",
                "org": "Institute of Photoelectronics"
            },
            {
                "name": "Feng-Yan Li",
                "org": "Institute of Photoelectronics"
            },
            {
                "name": "Li Zhang",
                "org": "Institute of Photoelectronics"
            },
            {
                "name": "Yu-Ming Xue",
                "org": "Institute of Photoelectronics"
            },
            {
                "name": "Zhi-Qiang Zhou",
                "org": "Institute of Photoelectronics"
            },
            {
                "name": "Qing He",
                "org": "Institute of Photoelectronics"
            }
        ],
        "title": "Preparation of Cu(In,Ga)Se 2 thin film solar cells by selenization of metallic precursors in an Ar atmosphere",
        "abstract": "Cu(In,Ga)Se ",
        "keywords": [
            ""
        ],
        "venue": "Chinese Physics Letters",
        "year": 2006,
        "id": "ZaLBCNYv"
    },
    "v7rgvzgI": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Medicinal Chemical Biology"
            },
            {
                "name": "Mao Chen",
                "org": "State Key Laboratory of Medicinal Chemical Biology"
            },
            {
                "name": "Lili Tian",
                "org": "State Key Laboratory of Medicinal Chemical Biology"
            },
            {
                "name": "Ying Guan",
                "org": "State Key Laboratory of Medicinal Chemical Biology"
            },
            {
                "name": "Yongjun Zhang",
                "org": "State Key Laboratory of Medicinal Chemical Biology"
            }
        ],
        "title": "Release of polyphenolic drugs from dynamically bonded layer-by-layer films",
        "abstract": "Layer-by-layer (LbL) assembled films have been exploited for surface-mediated drug delivery. The drugs loaded in the films were usually released via diffusion or the degradation of one of the film components. Here we demonstrate that drug release can also be achieved by exploiting the dynamic nature of hydrogen-bonded LbL films. The films were fabricated from tannic acid (TA), a model polyphenolic drug, and poly(vinyl pyrrolidone) (PVPON). The driving force for the film buildup is the hydrogen bonding between the two components, which was confirmed by Fourier transform infrared (FTIR) spectra. The film growth is linear, and the growth rate of the film decreases with increasing assembly temperature. Because of the reversible/dynamic nature of hydrogen bonding, when soaked in aqueous solutions, the PVPON/TA films disassemble gradually and thus release TA to the media. The release rate of TA increases with increasing pH and temperature but decreases with increasing ionic strength. Scanning electron microscopy (SEM) studies on the surface morphology of the film during TA release reveal that the film surface becomes smoother and then rougher again because of the dewetting of the film. The released TA can scavenge ABTS",
        "keywords": [
            "antioxidant acitivity",
            "drug release",
            "dynamic bonds",
            "hydrogen bonds",
            "layer-by-layer assembly",
            "polyphenolic drug"
        ],
        "venue": "ACS Applied Materials and Interfaces",
        "year": 2013,
        "id": "v7rgvzgI"
    },
    "lkHkMSo6": {
        "authors": [
            {
                "name": "Mao Chen",
                "org": "State Key Laboratory of Medicinal Chemical Biology"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Medicinal Chemical Biology"
            },
            {
                "name": "Ying Guan",
                "org": "State Key Laboratory of Medicinal Chemical Biology"
            },
            {
                "name": "Yongjun Zhang",
                "org": "State Key Laboratory of Medicinal Chemical Biology"
            }
        ],
        "title": "Polymerized microgel colloidal crystals: Photonic hydrogels with tunable band gaps and fast response rates",
        "abstract": "Into and out of the blue: The highly ordered structure of a PNIPAM microgel colloidal crystal (MCC) is stabilized by photopolymerization of its surface-bound vinyl groups. The resulting polymerized MCCs can respond reversibly and quickly to external stimuli, including temperature and ionic strength of the surrounding media, allowing the color (see picture) and band gap to be finely tuned in the whole visible range. \u00a9 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.",
        "keywords": [
            "colloidal crystals",
            "hydrogels",
            "microgels",
            "self-assembly",
            "stimuli-responsive"
        ],
        "venue": "Angewandte Chemie - International Edition",
        "year": 2013,
        "id": "lkHkMSo6"
    },
    "DzEWvGbp": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Institute of Chemical Materials, China Academy of Engineering Physics"
            },
            {
                "name": "Mao Chen",
                "org": "Institute of Chemical Materials, China Academy of Engineering Physics"
            },
            {
                "name": "Ying Guan",
                "org": "State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Functional Polymer Materials, Institute of Polymer Chemistry, College of Chemistry, Nankai University, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin)"
            },
            {
                "name": "Yongjun Zhang",
                "org": "State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Functional Polymer Materials, Institute of Polymer Chemistry, College of Chemistry, Nankai University, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin)"
            }
        ],
        "title": "Dynamic layer-by-layer films linked with Schiff base bond for sustained drug release",
        "abstract": "Dynamic layer-by-layer films were fabricated from a dextran-doxorubicin conjugate, PO-Dex-DOX, and glycol chitosan (GC), via the in situ Schiff base reaction between the aldehyde groups on PO-Dex-DOX and the amino groups on GC. Because of the reversible, dynamic nature of Schiff base bonds in the films, the films disintegrate gradually when soaked in aqueous solutions, and thus release DOX into the media. The release mechanism is different from ordinary drug carriers, in which the drug is usually released via diffusion or polymer degradation. The drug release rate decreases with increasing molecular weight of dextran. More importantly, because of the stimuli-responsivity of Schiff base bonds, the drug release rate can be tuned via external stimuli. Faster hydrolysis of Schiff base bonds at a lower pH and/or a higher temperature results in accelerated film disintegration and thus faster drug release. In vitro cytotoxicity test suggests that the released DOX retains its antitumor activity.",
        "keywords": [
            ""
        ],
        "venue": "RSC Advances",
        "year": 2015,
        "id": "DzEWvGbp"
    },
    "7JvImjr8": {
        "authors": [
            {
                "name": "Mao Chen",
                "org": "Key Laboratory of Functional Polymer Materials, State Key Laboratory of Medicinal Chemical Biology, Co-Innovation Center of Chemistry and Chemical Engineering of Tianjin, Institute of Polymer Chemistry, College of Chemistry, Nankai University"
            },
            {
                "name": "Yapeng Zhang",
                "org": "Key Laboratory of Functional Polymer Materials, State Key Laboratory of Medicinal Chemical Biology, Co-Innovation Center of Chemistry and Chemical Engineering of Tianjin, Institute of Polymer Chemistry, College of Chemistry, Nankai University"
            },
            {
                "name": "Siyu Jia",
                "org": "Key Laboratory of Functional Polymer Materials, State Key Laboratory of Medicinal Chemical Biology, Co-Innovation Center of Chemistry and Chemical Engineering of Tianjin, Institute of Polymer Chemistry, College of Chemistry, Nankai University"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Functional Polymer Materials, State Key Laboratory of Medicinal Chemical Biology, Co-Innovation Center of Chemistry and Chemical Engineering of Tianjin, Institute of Polymer Chemistry, College of Chemistry, Nankai University"
            },
            {
                "name": "Ying Guan",
                "org": "Key Laboratory of Functional Polymer Materials, State Key Laboratory of Medicinal Chemical Biology, Co-Innovation Center of Chemistry and Chemical Engineering of Tianjin, Institute of Polymer Chemistry, College of Chemistry, Nankai University"
            },
            {
                "name": "Yongjun Zhang",
                "org": "Key Laboratory of Functional Polymer Materials, State Key Laboratory of Medicinal Chemical Biology, Co-Innovation Center of Chemistry and Chemical Engineering of Tianjin, Institute of Polymer Chemistry, College of Chemistry, Nankai University"
            }
        ],
        "title": "Photonic Crystals with a Reversibly Inducible and Erasable Defect State Using External Stimuli",
        "abstract": "The controlled introduction of artificial extrinsic defects is critical to achieve the functions of photonic crystals. Smart defects capable of responding to external stimuli lead to more advanced applications. Here we report a microgel colloidal crystal with a defect state which could be induced and erased reversibly by external stimuli. The crystal was assembled from PNIPAM microgel and P(NIPAM-AAc) microgel of the same size. The resulting doped crystal does not exhibit a defect state in its stop band because of the similar optical properties of the dopant and the host. By increasing the pH value, however, the dopant P(NIPAM-AAc) spheres swell to a larger size and turn into real defects in the crystal, resulting in the appearance of defect state. Adjusting the pH value back restores the size of the dopant spheres, and thus erases the defect state. Temperature, a second external stimulus, could also be used to induce and erase defect states of the crystal. Artificial defects: Doped microgel colloidal crystals were facilely assembled from two microgels with the same size. A defect state in the crystals could be reversibly induced and erased by external stimuli (see picture).",
        "keywords": [
            "artificial defects",
            "colloidal crystals",
            "defect states",
            "microgels",
            "stimuli-responsive materials"
        ],
        "venue": "Angewandte Chemie - International Edition",
        "year": 2015,
        "id": "7JvImjr8"
    },
    "tQNjdXTu": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Wenzhong Wang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Shengwei Liu",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Lisha Zhang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Haolan Xu",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Wei Zhu",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            }
        ],
        "title": "A sonochemical route to visible-light-driven high-activity BiVO4 photocatalyst",
        "abstract": "Visible-light-induced BiVO",
        "keywords": [
            "BiVO4 nanocrystals",
            "Photocatalysis",
            "Photodegradation",
            "Sonochemical synthesis",
            "Visible light"
        ],
        "venue": "Journal of Molecular Catalysis A: Chemical",
        "year": 2006,
        "id": "tQNjdXTu"
    },
    "6kmFLbFt": {
        "authors": [
            {
                "name": "Lisha Zhang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Wenzhong Wang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Jiong Yang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Zhigang Chen",
                "org": "Laboratory of Advanced Materials"
            },
            {
                "name": "Wenqing Zhang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Shengwei Liu",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            }
        ],
        "title": "Sonochemical synthesis of nanocrystallite Bi",
        "abstract": "The synthesis of Bi",
        "keywords": [
            "Nanocrystallite Bi2O3",
            "Photocatalytic",
            "Sonochemical synthesis",
            "Visible light"
        ],
        "venue": "Applied Catalysis A: General",
        "year": 2006,
        "id": "6kmFLbFt"
    },
    "nYyzViXB": {
        "authors": [
            {
                "name": "Shengwei Liu",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Wenzhong Wang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Lisha Zhang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            }
        ],
        "title": "Silver vanadium oxides nanobelts and their chemical reduction to silver nanobelts",
        "abstract": "Uniform \u03b2-AgVO",
        "keywords": [
            "A1. Crystal morphology",
            "A2. Hydrothermal crystal growth",
            "B1. \u03b2-AgVO3",
            "B1. Nanomaterials"
        ],
        "venue": "Journal of Crystal Growth",
        "year": 2006,
        "id": "nYyzViXB"
    },
    "m6s6L1fr": {
        "authors": [
            {
                "name": "Haolan Xu",
                "org": "Graduate School"
            },
            {
                "name": "Wenzhong Wang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Wei Zhu",
                "org": "Graduate School"
            },
            {
                "name": "Lin Zhou",
                "org": "Graduate School"
            }
        ],
        "title": "Synthesis of octahedral CuS nanocages via a solid-liquid reaction",
        "abstract": "Octahedral CuS nanocages were synthesized by a solid-liquid reaction between solid Cu",
        "keywords": [
            ""
        ],
        "venue": "Nanotechnology",
        "year": 2006,
        "id": "m6s6L1fr"
    },
    "seXfdunL": {
        "authors": [
            {
                "name": "Wei Zhu",
                "org": "Graduate School"
            },
            {
                "name": "Wenzhong Wang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Haolan Xu",
                "org": "Graduate School"
            },
            {
                "name": "Lin Zhou",
                "org": "Graduate School"
            },
            {
                "name": "Lisha Zhang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Jianlin Shi",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            }
        ],
        "title": "Ultrasonic-induced growth of crystalline tellurium nanorods and related branched structures",
        "abstract": "An ultrasonic route for the preparation of tellurium nanorods in aqueous solution is established at room temperature. The as-obtained nanorods are characterized to be single crystalline with [0 0 1] growth orientation, and have 30-60 nm in diameter and 200-300 nm in length. Some branched architectures, consisting of several nanorods, are also found in the products. In the synthesis, tellurium nitrate powder is utilized as the tellurium source. UV-vis spectra are recorded at ordinal stages accompanying with the prolongation of the sonochemical reaction. Based on the anisotropic growth determined by the intrinsic linear crystallographic structure of trigonal tellurium, the shaping mechanism of the nanorods is investigated. And the formation of the branched structures is suggested to be the result of multi-nuclei growth in monomer colloid. \u00a9 2006 Elsevier B.V. All rights reserved.",
        "keywords": [
            "A1. Crystal morphology",
            "A1. Nanostructures",
            "A2. Growth from solutions",
            "A2. Single crystal growth"
        ],
        "venue": "Journal of Crystal Growth",
        "year": 2006,
        "id": "seXfdunL"
    },
    "BU7V8v5P": {
        "authors": [
            {
                "name": "Wei Zhu",
                "org": "Graduate School of the Chinese Academy of Sciences"
            },
            {
                "name": "Wenzhong Wang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Haolan Xu",
                "org": "Graduate School of the Chinese Academy of Sciences"
            },
            {
                "name": "Lin Zhou",
                "org": "Graduate School of the Chinese Academy of Sciences"
            },
            {
                "name": "Lisha Zhang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Jianlin Shi",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            }
        ],
        "title": "Controllable, surfactant-free growth of 2D, scroll-like tellurium nanocrystals via a modified polyol process",
        "abstract": "In this study, we demonstrate that single crystalline tellurium with a 2D, scroll-like structure that deviates from the intrinsic linear crystallographic nature can be controllably synthesized via a modified polyol process by the reduction of tellurium nitrate (Te-N-O) in refluxing ethylene glycol, where no growth modifier such as surfactants or templates is involved. In the preparation, the kinetic control of the 2D growth is primarily manipulated by modulating the Te-N-O concentration in the solution. The morphology depends on the how the reactant is added. Stepwise addition of the reactant Te-N-O is crucial for the formation of the scroll-like morphology. It is demonstrated that ID tubular products with sharp tips rather than 2D structures are achieved when Te-N-O with equal quantity is injected in one step. Lowering the reaction temperature is favorable to the shape perfection of the nanotubes. On the basis of the characterizations, we propose the formation mechanism of this unique 2D structure to be an asymmetric growth process and subsequent epitaxial evolution. As the first report about 2D tellurium nanostructure, this strategy is attractive for enhancing the comprehension about the growth behavior of tellurium nanocrystals in solution system, which is helpful for the following property investigation and potential applications in nanotechnology. \u00a9 2006 American Chemical Society.",
        "keywords": [
            ""
        ],
        "venue": "Crystal Growth and Design",
        "year": 2006,
        "id": "BU7V8v5P"
    },
    "wWVVrlSg": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "School of Chemical Engineering and Technology"
            },
            {
                "name": "Xin Tan",
                "org": "School of Environment Science and Technology"
            },
            {
                "name": "Lin Zhao",
                "org": "School of Environment Science and Technology"
            },
            {
                "name": "Ming Sun",
                "org": "School of Environment Science and Technology"
            }
        ],
        "title": "Photocatalytic degradation of NOx over platinum and nitrogen codoped titanium dioxide under visible light irradiation",
        "abstract": "In order to utilize visible light and enhance the catalytic efficiency in photocatalytic conversion of NO",
        "keywords": [
            "Environment",
            "Heterogeneous catalysis",
            "Nitrogen and platinum codoped titania",
            "Nitrogen oxides",
            "Photocatalysis",
            "Photochemistry",
            "Visible light induced"
        ],
        "venue": "Collection of Czechoslovak Chemical Communications",
        "year": 2007,
        "id": "wWVVrlSg"
    },
    "P412BZci": {
        "authors": [
            {
                "name": "X. Ni",
                "org": "Department of Physics"
            },
            {
                "name": "\u00dc. \u00d6zg\u00fcr",
                "org": ""
            },
            {
                "name": "A.A. Baski",
                "org": ""
            },
            {
                "name": "H. Morko\u0327",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Electrical and Computer Engineering"
            },
            {
                "name": "David J. Smith",
                "org": "Department of Electrical and Computer Engineering"
            },
            {
                "name": "C.A. Tran",
                "org": "SemiLEDs"
            }
        ],
        "title": "Epitaxial lateral overgrowth of (11 2- 2) semipolar GaN on (1 1- 00) m -plane sapphire by metalorganic chemical vapor deposition",
        "abstract": "The authors report the growth of semipolar (11 2- 2) GaN films on nominally on-axis (10 1- 0) m -plane sapphire substrates using metal organic chemical vapor deposition. High-resolution x-ray diffraction (XRD) results indicate a preferred (11 2- 2) GaN orientation. Moreover, epitaxial lateral overgrowth (ELO) of GaN was carried out on the (11 2- 2) oriented GaN templates. When the ELO stripes were aligned along [11 2- 0]sapphire, the Ga-polar wings were inclined by 32\u00b0 with respect to the substrate plane with smooth extended nonpolar a -plane GaN surfaces and polar c -plane GaN growth fronts. When compared with the template, the on-axis and off-axis XRD rocking curves indicated significant improvement in the crystalline quality by ELO for this mask orientation (on-axis 1700 arc sec for the template, 380 arc sec for the ELO sample, when rocked toward the GaN m axis), as verified by transmission electron microscopy (TEM). For growth mask stripes aligned along [0001]sapphire with GaN m -plane as growth fronts, the surface was composed of two 10 1- 1 planes making a 26\u00b0 angle with the substrate plane. For this mask orientation XRD and TEM showed no improvement in the crystalline quality by ELO when compared to the non-ELO template. \u00a9 2007 American Institute of Physics.",
        "keywords": [
            ""
        ],
        "venue": "Applied Physics Letters",
        "year": 2007,
        "id": "P412BZci"
    },
    "VxQOu9Rm": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Wenzhong Wang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Lisha Zhang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            }
        ],
        "title": "Ultrasonic-assisted synthesis of visible-light-induced Bi2MO6 (M = W, Mo) photocatalysts",
        "abstract": "Visible-light-induced photocatalysts Bi",
        "keywords": [
            "Bi2MO6 (M = W, Mo)",
            "Photocatalysis",
            "RhB",
            "Ultrasonic",
            "Visible light"
        ],
        "venue": "Journal of Molecular Catalysis A: Chemical",
        "year": 2007,
        "id": "VxQOu9Rm"
    },
    "N5I8asjO": {
        "authors": [
            {
                "name": "Lisha Zhang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Wenzhong Wang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Zhigang Chen",
                "org": "Laboratory of Advanced Materials"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Haolan Xu",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Wei Zhu",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            }
        ],
        "title": "Fabrication of flower-like Bi",
        "abstract": "A novel flower-like Bi",
        "keywords": [
            ""
        ],
        "venue": "Journal of Materials Chemistry",
        "year": 2007,
        "id": "N5I8asjO"
    },
    "Q4zNnxyy": {
        "authors": [
            {
                "name": "Xin Tan",
                "org": "School of Environmental Science and Technology"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Chemical Engineering and Technology"
            },
            {
                "name": "Tao Yu",
                "org": "School of Environmental Science and Technology"
            },
            {
                "name": "Ruidong Yang",
                "org": "School of Chemical Engineering and Technology"
            },
            {
                "name": "Lin Zhao",
                "org": "School of Environmental Science and Technology"
            }
        ],
        "title": "Photocatalytic degradation of NOx under visible light irradiation using Fe-doped titanium dioxide",
        "abstract": "In order to utilize visible light in photocatalytic conversion of NO",
        "keywords": [
            "Fe-doped titania",
            "Nitrogen oxides",
            "Photocatalysis",
            "Visible light induced"
        ],
        "venue": "Transactions of Tianjin University",
        "year": 2007,
        "id": "Q4zNnxyy"
    },
    "rPBB33qD": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Wenzhong Wang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Lisha Zhang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Haolan Xu",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Wei Zhu",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            }
        ],
        "title": "Single-crystalline BiVO4 microtubes with square cross-sections: Microstructure, growth mechanism, and photocatalytic property",
        "abstract": "Single-crystalline bismuth vanadate (BiVO",
        "keywords": [
            ""
        ],
        "venue": "Journal of Physical Chemistry C",
        "year": 2007,
        "id": "rPBB33qD"
    },
    "OHn0MSV9": {
        "authors": [
            {
                "name": "Lisha Zhang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructures"
            },
            {
                "name": "Wenzhong Wang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructures"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructures"
            },
            {
                "name": "Haolan Xu",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructures"
            }
        ],
        "title": "Bi2WO6 Nano- And microstructures: Shape control and associated visible-light-driven photocatalytic activities",
        "abstract": "The shape-controlled synthesis of nano- and microstructured materials has opened up new possibilities to improve their physical and chemical properties. In this work, new types of Bi",
        "keywords": [
            "Microstructures",
            "Nanostructures",
            "Optical properties",
            "Photocatatysis"
        ],
        "venue": "Small",
        "year": 2007,
        "id": "OHn0MSV9"
    },
    "WxsJ1u07": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Xin Tan",
                "org": ""
            },
            {
                "name": "Lin Zhao",
                "org": ""
            },
            {
                "name": "Ming Sun",
                "org": ""
            }
        ],
        "title": "Photocatalytic oxidation of NO x over visible-light-responsive nitrogen-doped TiO2 ",
        "abstract": "In order to utilize visible-light in photocatalytic conversion of NO ",
        "keywords": [
            "Environment",
            "Nitrogen doped titania",
            "Nitrogen oxides",
            "Photocatalysis",
            "Visible-light induced"
        ],
        "venue": "Korean Journal of Chemical Engineering",
        "year": 2007,
        "id": "WxsJ1u07"
    },
    "7WMZd6oM": {
        "authors": [
            {
                "name": "Haolan Xu",
                "org": "Graduate School"
            },
            {
                "name": "Wenzhong Wang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Wei Zhu",
                "org": "Graduate School"
            },
            {
                "name": "Lin Zhou",
                "org": "Graduate School"
            },
            {
                "name": "Meilin Ruan",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            }
        ],
        "title": "Hierarchical-oriented attachment: From one-dimensional Cu(OH)2 nanowires to two-dimensional CuO nanoleaves",
        "abstract": "One-dimensional (ID) Cu(OH)",
        "keywords": [
            ""
        ],
        "venue": "Crystal Growth and Design",
        "year": 2007,
        "id": "7WMZd6oM"
    },
    "INHO1srh": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Wenzhong Wang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Haolan Xu",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            }
        ],
        "title": "Controllable synthesis of three-dimensional well-defined BiVO 4 mesocrystals via a facile additive-free aqueous strategy",
        "abstract": "The controllable synthesis of two novel types of BiVO ",
        "keywords": [
            ""
        ],
        "venue": "Crystal Growth and Design",
        "year": 2008,
        "id": "INHO1srh"
    },
    "f0FCrMIo": {
        "authors": [
            {
                "name": "Meng Shang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Wenzhong Wang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Songmei Sun",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Ling Zhang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            }
        ],
        "title": "Bi2WO6 nanocrystals with high photocatalytic activities under visible light",
        "abstract": "Visible-light-induced photocatalyst Bi",
        "keywords": [
            ""
        ],
        "venue": "Journal of Physical Chemistry C",
        "year": 2008,
        "id": "f0FCrMIo"
    },
    "Ued9uJOV": {
        "authors": [
            {
                "name": "Haolan Xu",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Wenzhong Wang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            }
        ],
        "title": "A growth model of single crystalline hollow spheres: Oriented attachment of Cu2O nanoparticles to the single crystalline shell wall",
        "abstract": "A growth mechanism for single crystalline hollow spheres was proposed based on the study of the formation process of single crystalline Cu",
        "keywords": [
            ""
        ],
        "venue": "Crystal Growth and Design",
        "year": 2008,
        "id": "Ued9uJOV"
    },
    "491gpg3q": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Wenzhong Wang",
                "org": ""
            },
            {
                "name": "Haolan Xu",
                "org": ""
            },
            {
                "name": "Songmei Sun",
                "org": ""
            }
        ],
        "title": "Template-free fabrication of CdMoO4 hollow spheres and their morphology-dependent photocatalytic property",
        "abstract": "The controllable synthesis of CdMoO",
        "keywords": [
            ""
        ],
        "venue": "Crystal Growth and Design",
        "year": 2008,
        "id": "491gpg3q"
    },
    "pTRGivQT": {
        "authors": [
            {
                "name": "Songmei Sun",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Wenzhong Wang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Haolan Xu",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Meng Shang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Ling Zhang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            }
        ],
        "title": "Bi5FeTi3O15 hierarchical microflowers: Hydrothermal synthesis, growth mechanism, and associated visible-light-driven photocatalysis",
        "abstract": "Nanostructured Bi",
        "keywords": [
            ""
        ],
        "venue": "Journal of Physical Chemistry C",
        "year": 2008,
        "id": "pTRGivQT"
    },
    "OwUvBvLp": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructures"
            },
            {
                "name": "Wenzhong Wang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructures"
            },
            {
                "name": "Haolan Xu",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructures"
            },
            {
                "name": "Songmei Sun",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructures"
            },
            {
                "name": "Meng Shang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructures"
            }
        ],
        "title": "Bi2O3 hierarchical nanostructures: Controllable synthesis, growth mechanism, and their application in photocatalysis",
        "abstract": "By introducing VO",
        "keywords": [
            "Bismuth oxide",
            "Crystal growth",
            "Nanostructures, photochemistry"
        ],
        "venue": "Chemistry - A European Journal",
        "year": 2009,
        "id": "OwUvBvLp"
    },
    "qERCumRx": {
        "authors": [
            {
                "name": "Songmei Sun",
                "org": ""
            },
            {
                "name": "Wenzhong Wang",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Haolan Xu",
                "org": ""
            }
        ],
        "title": "Efficient methylene blue removal over hydrothermally synthesized starlike BiVO4 ",
        "abstract": "Nanoplate-stacked starlike BiVO",
        "keywords": [
            ""
        ],
        "venue": "Industrial and Engineering Chemistry Research",
        "year": 2009,
        "id": "qERCumRx"
    },
    "KVSGkREp": {
        "authors": [
            {
                "name": "Songmei Sun",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Wenzhong Wang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Ling Zhang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Wenzong Yin",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Meng Shang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            }
        ],
        "title": "Visible light-induced efficient contaminant removal by Bi5O 7I",
        "abstract": "A new visible light-driven photocatalyst, Bi",
        "keywords": [
            ""
        ],
        "venue": "Environmental Science and Technology",
        "year": 2009,
        "id": "KVSGkREp"
    },
    "K0LUBS2K": {
        "authors": [
            {
                "name": "Ling Zhang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructures"
            },
            {
                "name": "Wenzhong Wang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructures"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructures"
            },
            {
                "name": "Meng Shang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructures"
            },
            {
                "name": "Songmei Sun",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructures"
            }
        ],
        "title": "Fe3O4 coupled BiOCl: A highly efficient magnetic photocatalyst",
        "abstract": "The magnetic photocatalyst, Fe",
        "keywords": [
            "BiOCl",
            "Coupled structure",
            "Magnetic nanoparticles",
            "Photocatalyst"
        ],
        "venue": "Applied Catalysis B: Environmental",
        "year": 2009,
        "id": "K0LUBS2K"
    },
    "BbwV6aXX": {
        "authors": [
            {
                "name": "Meng Shang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Wenzhong Wang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Ling Zhang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Songmei Sun",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Lu Wang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            }
        ],
        "title": "3D Bi2WO6/TiO2 hierarchical heterostructure: Controllable synthesis and enhanced visible photocatalytic degradation performances",
        "abstract": "A three-dimensional (3D) multicomponent oxide, Bi",
        "keywords": [
            ""
        ],
        "venue": "Journal of Physical Chemistry C",
        "year": 2009,
        "id": "BbwV6aXX"
    },
    "9EDgCxyF": {
        "authors": [
            {
                "name": "Wenzong Yin",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Wenzhong Wang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Meng Shang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Songmei Sun",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Lu Wang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            }
        ],
        "title": "BiVO4 hollow nanospheres: Anchoring synthesis, growth mechanism, and their application in photocatalysis",
        "abstract": "An anchoring method was developed to synthesize monoclinic BiVO",
        "keywords": [
            "Bismuth",
            "Nanostructures",
            "Photochemistry",
            "Template synthesis",
            "Vanadates"
        ],
        "venue": "European Journal of Inorganic Chemistry",
        "year": 2009,
        "id": "9EDgCxyF"
    },
    "1CRxtubz": {
        "authors": [
            {
                "name": "Meng Shang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructures"
            },
            {
                "name": "Wenzhong Wang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructures"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructures"
            },
            {
                "name": "Songmei Sun",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructures"
            },
            {
                "name": "Wenzong Yin",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructures"
            }
        ],
        "title": "Nanosized BiVO4 with high visible-light-induced photocatalytic activity: Ultrasonic-assisted synthesis and protective effect of surfactant",
        "abstract": "Nanosized BiVO",
        "keywords": [
            "BiVO4",
            "Nanosize",
            "PEG",
            "Ultrasonic",
            "Visible-light photocatalysis"
        ],
        "venue": "Journal of Hazardous Materials",
        "year": 2009,
        "id": "1CRxtubz"
    },
    "6DUDrOAs": {
        "authors": [
            {
                "name": "Meng Shang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Wenzhong Wang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Songmei Sun",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Jia Ren",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Ling Zhang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            }
        ],
        "title": "Efficient visible light-induced photocatalytic degradation of contaminant by spindle-like PANI/BiVO4 ",
        "abstract": "Photocatalytic active spindle-like BiVO",
        "keywords": [
            ""
        ],
        "venue": "Journal of Physical Chemistry C",
        "year": 2009,
        "id": "6DUDrOAs"
    },
    "MC7WSET5": {
        "authors": [
            {
                "name": "Wenzong Yin",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Wenzhong Wang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Songmei Sun",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Ling Zhang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            }
        ],
        "title": "CTAB-assisted synthesis of monoclinic BiVO4 photocatalyst and its highly efficient degradation of organic dye under visible-light irradiation",
        "abstract": "A highly efficient monoclinic BiVO",
        "keywords": [
            "Conjugated chromophore structure",
            "CTAB",
            "De-ethylation",
            "Monoclinic BiVO4",
            "Photocatalyst"
        ],
        "venue": "Journal of Hazardous Materials",
        "year": 2010,
        "id": "MC7WSET5"
    },
    "1SPdjmvo": {
        "authors": [
            {
                "name": "Bo Li",
                "org": "Center for Nanochemistry"
            },
            {
                "name": "Lin Zhou",
                "org": "Center for Nanochemistry"
            },
            {
                "name": "Di Wu",
                "org": "Center for Nanochemistry"
            },
            {
                "name": "Hailin Peng",
                "org": "Center for Nanochemistry"
            },
            {
                "name": "Kai Yan",
                "org": "Center for Nanochemistry"
            },
            {
                "name": "Yu Zhou",
                "org": "Center for Nanochemistry"
            },
            {
                "name": "Zhongfan Liu",
                "org": "Center for Nanochemistry"
            }
        ],
        "title": "Photochemical chlorination of graphene",
        "abstract": "We report the covalent functionalization of graphene by photochemical chlorination. The gas-phase photochlorination of graphene, followed by the structural transformation of the C-C bonds from sp",
        "keywords": [
            "band gap opening",
            "covalent functionalization",
            "graphene",
            "photochemical chlorination"
        ],
        "venue": "ACS Nano",
        "year": 2011,
        "id": "1SPdjmvo"
    },
    "cP5LWnli": {
        "authors": [
            {
                "name": "Di Wu",
                "org": ""
            },
            {
                "name": "Bo Li",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Hailin Peng",
                "org": ""
            },
            {
                "name": "Kai Yan",
                "org": ""
            },
            {
                "name": "Yu Zhou",
                "org": ""
            },
            {
                "name": "Zhongfan Liu",
                "org": ""
            }
        ],
        "title": "Properties of photochlorinated graphene",
        "abstract": "We report the synthesis and electronic properties of chlorinated graphene, a totally new graphene derivative. The gas-phase photochlorination of graphene, followed by the structural transformation of the C-C bonds from sp ",
        "keywords": [
            ""
        ],
        "venue": "2011 IEEE Nanotechnology Materials and Devices Conference, NMDC 2011",
        "year": 2011,
        "id": "cP5LWnli"
    },
    "e5G9uBvY": {
        "authors": [
            {
                "name": "Wen-Zhong Wang",
                "org": "Shanghai Institute of Ceramics"
            },
            {
                "name": "Meng Shang",
                "org": "Shanghai Institute of Ceramics"
            },
            {
                "name": "Wen-Zong Yin",
                "org": "Shanghai Institute of Ceramics"
            },
            {
                "name": "Jia Ren",
                "org": "Shanghai Institute of Ceramics"
            },
            {
                "name": "Lin Zhou",
                "org": "Shanghai Institute of Ceramics"
            }
        ],
        "title": "Recent progress on the bismuth containing complex oxide photocatalysts",
        "abstract": "Photocatalysts could utilize solar energy to remedy environmental pollutions thus attract world wide attention. Some bismuth-containing complex oxides could be activated by visible light and mineralize organic pollutants. In this paper we reviewed recent progresses on the development of Bi ",
        "keywords": [
            "Bismuth containing complex oxides",
            "Environmental remediation",
            "Photocatalyst",
            "Review",
            "Visible light"
        ],
        "venue": "Wuji Cailiao Xuebao/Journal of Inorganic Materials",
        "year": 2012,
        "id": "e5G9uBvY"
    },
    "UQNALi1q": {
        "authors": [
            {
                "name": "Mingmei Yang",
                "org": "Center for Nanochemistry"
            },
            {
                "name": "Lin Zhou",
                "org": "Center for Nanochemistry"
            },
            {
                "name": "Jinying Wang",
                "org": "Center for Nanochemistry"
            },
            {
                "name": "Zhongfan Liu",
                "org": "Center for Nanochemistry"
            },
            {
                "name": "Zhirong Liu",
                "org": "Center for Nanochemistry"
            }
        ],
        "title": "Evolutionary chlorination of graphene: From charge-transfer complex to covalent bonding and nonbonding",
        "abstract": "Density functional theory (DFT) studies were performed to investigate the chlorination of graphene. Unlike hydrogenation and fluorination, where the adsorption of H and F is always by covalent C-H/C-F bonding, Cl atoms generate various states when single-sided graphene exposed. In the initial reaction stage, it forms Cl-graphene charge-transfer complex, where the C orbitals keep sp ",
        "keywords": [
            ""
        ],
        "venue": "Journal of Physical Chemistry C",
        "year": 2012,
        "id": "UQNALi1q"
    },
    "nZMmnKFN": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Beijing National Laboratory for Molecular Sciences"
            },
            {
                "name": "Lushan Zhou",
                "org": "Beijing National Laboratory for Molecular Sciences"
            },
            {
                "name": "Mingmei Yang",
                "org": "Beijing National Laboratory for Molecular Sciences"
            },
            {
                "name": "Di Wu",
                "org": "Beijing National Laboratory for Molecular Sciences"
            },
            {
                "name": "Lei Liao",
                "org": "Beijing National Laboratory for Molecular Sciences"
            },
            {
                "name": "Kai Yan",
                "org": "Beijing National Laboratory for Molecular Sciences"
            },
            {
                "name": "Qin Xie",
                "org": "Beijing National Laboratory for Molecular Sciences"
            },
            {
                "name": "Zhirong Liu",
                "org": "Beijing National Laboratory for Molecular Sciences"
            },
            {
                "name": "Hailin Peng",
                "org": "Beijing National Laboratory for Molecular Sciences"
            },
            {
                "name": "Zhongfan Liu",
                "org": "Beijing National Laboratory for Molecular Sciences"
            }
        ],
        "title": "Free radical reactions in two dimensions: A case study on photochlorination of graphene",
        "abstract": "Graphene, a two-dimensional giant-molecule of sp",
        "keywords": [
            "chemical modification",
            "doping",
            "free radical reactions",
            "graphene",
            "photochlorination"
        ],
        "venue": "Small",
        "year": 2013,
        "id": "nZMmnKFN"
    },
    "B4Edz9xw": {
        "authors": [
            {
                "name": "Liming Zhang",
                "org": "Beijing National Laboratory for Molecular Sciences"
            },
            {
                "name": "Lin Zhou",
                "org": "Beijing National Laboratory for Molecular Sciences"
            },
            {
                "name": "Mingmei Yang",
                "org": "Beijing National Laboratory for Molecular Sciences"
            },
            {
                "name": "Zhirong Liu",
                "org": "Beijing National Laboratory for Molecular Sciences"
            },
            {
                "name": "Qin Xie",
                "org": "Beijing National Laboratory for Molecular Sciences"
            },
            {
                "name": "Hailin Peng",
                "org": "Beijing National Laboratory for Molecular Sciences"
            },
            {
                "name": "Zhongfan Liu",
                "org": "Beijing National Laboratory for Molecular Sciences"
            }
        ],
        "title": "Photo-induced free radical modification of graphene",
        "abstract": "Graphene has stimulated enormous interest due to its intriguing structure and fascinating properties. The extremely high carrier mobility, mechanical flexibility, and optical transparency as well as the versatility for band structure engineering make graphene a promising candidate for next-generation carbon-based electronic devices. Graphene chemistry, the covalent functionalization of graphene as a 2D giant molecule, offers a promising direction to controllably tailor its properties through the introduction of various chemical decorations. One of the great challenges for graphene functionalization originates from its strong chemical stability, thus highly reactive chemical species are needed as the reactants. In recent years, novel photochemical approaches have been developed to achieve efficient graphene modification and bandgap modulation, following a general concept of \"Photochemical Bandgap Engineering of Graphene\". In this article, such kinds of photochemical graphene engineering are demonstrated, together with a brief discussion on the future directions, challenges, and opportunities in this fascinating research area. Free radicals (X\u00b7) are photogenerated under illumination from neutral X",
        "keywords": [
            "graphene",
            "janus graphene",
            "photocatalytic techniques",
            "photochemistry",
            "photochlorination"
        ],
        "venue": "Small",
        "year": 2013,
        "id": "B4Edz9xw"
    },
    "jgwJko7S": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "University of the Chinese Academy of Sciences"
            },
            {
                "name": "Shilie Pan",
                "org": "Xinjiang Key Laboratory of Electronic Information Materials and Devices, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences"
            },
            {
                "name": "Xiaoyu Dong",
                "org": "University of the Chinese Academy of Sciences"
            },
            {
                "name": "Hongwei Yu",
                "org": "University of the Chinese Academy of Sciences"
            },
            {
                "name": "Hongping Wu",
                "org": "Xinjiang Key Laboratory of Electronic Information Materials and Devices, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences"
            },
            {
                "name": "Fangfang Zhang",
                "org": "Xinjiang Key Laboratory of Electronic Information Materials and Devices, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences"
            },
            {
                "name": "Zhongxiang Zhou",
                "org": "Xinjiang Key Laboratory of Electronic Information Materials and Devices, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences"
            }
        ],
        "title": "Na<inf>2</inf>Cd<inf>7</inf>B<inf>8</inf>O<inf>20</inf>: A new noncentrosymmetric compound with special [B<inf>3</inf>O<inf>7</inf>] units",
        "abstract": "A new noncentrosymmetric compound, Na<inf>2</inf>Cd<inf>7</inf>B <inf>8</inf>O<inf>20</inf>, has been synthesized by solid-state reaction for the first time. The crystal structure has been determined from single crystal X-ray diffraction data. The compound crystallizes in the orthorhombic space group Fdd2 with a = 51.5597(7) \u00c5, b = 58.6920(8) \u00c5 and c = 3.381 \u00c5. The crystal structure is composed of CdO<inf>n</inf> (n = 6, 7), Na-CdO <inf>n</inf> (n = 5, 6) NaO<inf>n</inf> (n = 4, 6) polyhedra, [B <inf>3</inf>O<inf>7</inf>] and [BO<inf>3</inf>] units. The [B<inf>3</inf>O <inf>7</inf>] unit is built up of three [BO<inf>3</inf>] groups via corner-sharing, rarely found in borate compounds. The IR spectrum, the optical diffuse reflectance spectrum and nonlinear optical properties of Na <inf>2</inf>Cd<inf>7</inf>B<inf>8</inf>O<inf>20</inf> are reported. \u00a9 2013 This journal isThe Royal Society of Chemistry.",
        "keywords": [
            ""
        ],
        "venue": "CrystEngComm",
        "year": 2013,
        "id": "jgwJko7S"
    },
    "RPRW3ASs": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "University of the Chinese Academy of Sciences"
            },
            {
                "name": "Shilie Pan",
                "org": "Xinjiang Technical Institute of Physics and Chemistry"
            },
            {
                "name": "Xin Su",
                "org": "Xinjiang Technical Institute of Physics and Chemistry"
            },
            {
                "name": "Hongwei Yu",
                "org": "University of the Chinese Academy of Sciences"
            },
            {
                "name": "Zhihua Yang",
                "org": "Xinjiang Technical Institute of Physics and Chemistry"
            },
            {
                "name": "Fangfang Zhang",
                "org": "Xinjiang Technical Institute of Physics and Chemistry"
            },
            {
                "name": "Zhongxiang Zhou",
                "org": "Xinjiang Technical Institute of Physics and Chemistry"
            },
            {
                "name": "Shujuan Han",
                "org": "Xinjiang Technical Institute of Physics and Chemistry"
            }
        ],
        "title": "Synthesis, crystal structure and optical properties of a new lithium dilead pentaborate, LiPb",
        "abstract": "A novel lithium dilead pentaborate compound, LiPb",
        "keywords": [
            "LiPb2B5O10 Borate Synthesis Crystal structure"
        ],
        "venue": "Journal of Molecular Structure",
        "year": 2013,
        "id": "RPRW3ASs"
    },
    "3frrhgAn": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "University of Chinese Academy of Sciences"
            },
            {
                "name": "Shilie Pan",
                "org": "Xinjiang Technical Institute of Physics and Chemistry"
            },
            {
                "name": "Xin Su",
                "org": "Xinjiang Technical Institute of Physics and Chemistry"
            },
            {
                "name": "Zhihua Yang",
                "org": "Xinjiang Technical Institute of Physics and Chemistry"
            },
            {
                "name": "Hongping Wu",
                "org": "Xinjiang Technical Institute of Physics and Chemistry"
            },
            {
                "name": "Hongwei Yu",
                "org": "University of Chinese Academy of Sciences"
            },
            {
                "name": "Fangfang Zhang",
                "org": "Xinjiang Technical Institute of Physics and Chemistry"
            },
            {
                "name": "Sifang Cui",
                "org": "School of Optical and Electronic Information"
            },
            {
                "name": "Zhongxiang Zhou",
                "org": "Xinjiang Technical Institute of Physics and Chemistry"
            }
        ],
        "title": "Synthesis, crystal structure, optical properties and theoretical calculations of a new potassium lead pentaborate, KPbB",
        "abstract": "A new potassium lead pentaborate compound, KPbB",
        "keywords": [
            "Crystal structure",
            "KPbB5O9",
            "Synthesis",
            "Theoretical calculations"
        ],
        "venue": "Journal of Molecular Structure",
        "year": 2013,
        "id": "3frrhgAn"
    },
    "n5PDkGMf": {
        "authors": [
            {
                "name": "Bao-Zhu Lin",
                "org": "Quantum-Functional Semiconductor Research Center, Dongguk University"
            },
            {
                "name": "Lin Zhou",
                "org": "Quantum-Functional Semiconductor Research Center, Dongguk University"
            },
            {
                "name": "Sh.U. Yuldashev",
                "org": "Quantum-Functional Semiconductor Research Center, Dongguk University"
            },
            {
                "name": "De-Jun Fu",
                "org": "Wuhan University, Dept Phys"
            },
            {
                "name": "Tae-Won Kang",
                "org": "Quantum-Functional Semiconductor Research Center, Dongguk University"
            }
        ],
        "title": "Optical and ferromagnetic properties of Cr doped ZnO nanorods",
        "abstract": "ZnO nanorods doped with 1-2 wt% Cr were grown on Si substrates by hydrothermal method. Scanning electron spectroscopy and X-ray diffraction show the hexagonal structure of the nanorods with ZnO oriented along (1 0 0), (0 0 2), (1 0 1) and (1 0 2) and CrO",
        "keywords": [
            "Magnetism",
            "Photoluminescence",
            "Semiconductors",
            "ZnO"
        ],
        "venue": "Applied Surface Science",
        "year": 2014,
        "id": "n5PDkGMf"
    },
    "qQjKlPie": {
        "authors": [
            {
                "name": "Wang Ping Duan",
                "org": ""
            },
            {
                "name": "Qing Wang",
                "org": ""
            },
            {
                "name": "Fang Li",
                "org": ""
            },
            {
                "name": "Chuan Xiang",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Jia Ke Xu",
                "org": ""
            },
            {
                "name": "Hao Tian Feng",
                "org": ""
            },
            {
                "name": "Xiao Chun Wei",
                "org": ""
            }
        ],
        "title": "Anti-catabolic effect of caffeic acid phenethyl ester, an active component of honeybee propolis on bone loss in ovariectomized mice: A micro-computed tomography study and histological analysis",
        "keywords": [
            "Bone loss",
            "Caffeic acid phenethyl ester",
            "Micro-computed tomography",
            "Osteoporosis"
        ],
        "venue": "Chinese Medical Journal",
        "year": 2014,
        "id": "qQjKlPie"
    },
    "rkOKkvcm": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application, College of Chemistry, Chemical Engineering and Materials Science, Soochow University"
            },
            {
                "name": "Han Zhang",
                "org": "Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application, College of Chemistry, Chemical Engineering and Materials Science, Soochow University"
            },
            {
                "name": "Yanping Luan",
                "org": "Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application, College of Chemistry, Chemical Engineering and Materials Science, Soochow University"
            },
            {
                "name": "Si Cheng",
                "org": "Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application, College of Chemistry, Chemical Engineering and Materials Science, Soochow University"
            },
            {
                "name": "Li-Juan Fan",
                "org": "Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application, College of Chemistry, Chemical Engineering and Materials Science, Soochow University"
            }
        ],
        "title": "Amplified detection of iron ion based on plasmon enhanced fluorescence and subsequently fluorescence quenching",
        "abstract": "A facile and rapid approach for detecting low concentration of iron ion (Fe",
        "keywords": [
            "Fluorescence quenching",
            "Gold\u2013silver alloy",
            "Iron ion",
            "Plasmon enhanced fluorescence"
        ],
        "venue": "Nano-Micro Letters",
        "year": 2014,
        "id": "rkOKkvcm"
    },
    "wiK35hHR": {
        "authors": [
            {
                "name": "Ruiying Miao",
                "org": "National Engineering Research Center for Rare Earth Materials, General Research Institute for Nonferrous Metals, Grirem Advanced Materials Co. Ltd."
            },
            {
                "name": "Xiaowei Zhang",
                "org": "National Engineering Research Center for Rare Earth Materials, General Research Institute for Nonferrous Metals, Grirem Advanced Materials Co. Ltd."
            },
            {
                "name": "Qiong Zhu",
                "org": "National Engineering Research Center for Rare Earth Materials, General Research Institute for Nonferrous Metals, Grirem Advanced Materials Co. Ltd."
            },
            {
                "name": "Zhiqi Zhang",
                "org": "National Engineering Research Center for Rare Earth Materials, General Research Institute for Nonferrous Metals, Grirem Advanced Materials Co. Ltd."
            },
            {
                "name": "Zhiqiang Wang",
                "org": "National Engineering Research Center for Rare Earth Materials, General Research Institute for Nonferrous Metals, Grirem Advanced Materials Co. Ltd."
            },
            {
                "name": "Shihong Yan",
                "org": "National Engineering Research Center for Rare Earth Materials, General Research Institute for Nonferrous Metals, Grirem Advanced Materials Co. Ltd."
            },
            {
                "name": "Dehong Chen",
                "org": "National Engineering Research Center for Rare Earth Materials, General Research Institute for Nonferrous Metals, Grirem Advanced Materials Co. Ltd."
            },
            {
                "name": "Lin Zhou",
                "org": "National Engineering Research Center for Rare Earth Materials, General Research Institute for Nonferrous Metals, Grirem Advanced Materials Co. Ltd."
            },
            {
                "name": "Zong'An Li",
                "org": "National Engineering Research Center for Rare Earth Materials, General Research Institute for Nonferrous Metals, Grirem Advanced Materials Co. Ltd."
            }
        ],
        "title": "Impurities especially titanium in the rare earth metal gadolinium - Before and after solid state electrotransport",
        "abstract": "Gadolinium was prepared by conventional procedures of fluorination, reduction, distillation and solid state electrotransport (SSE). The electronegativities of the metals were found to have an important influence on the electrotransport process and result of the impurity element. Meanwhile, titanium particles in the distilled gadolinium as major metallic impurities were studied by high resolution transmission electron microscopy (HRTEM) before and after solid state electrotransport. The results showed that impurities especially titanium transported from anode to cathode during SSE. In the metal before SSE, there were impurities of titanium in strip shape or embedded round shape. After SSE processing, titanium particles in the metal smaller than 50 nm in the cathode, but existed 6 to 10 times bigger in the anode.",
        "keywords": [
            "gadolinium",
            "impurities",
            "rare earth metal",
            "solid state electrotransport",
            "titanium"
        ],
        "venue": "Journal of Rare Earths",
        "year": 2014,
        "id": "wiK35hHR"
    },
    "rA0epqQm": {
        "authors": [
            {
                "name": "Jin Cai",
                "org": ""
            },
            {
                "name": "Gengze Wu",
                "org": ""
            },
            {
                "name": "Xiaorong Tan",
                "org": ""
            },
            {
                "name": "Yu Han",
                "org": ""
            },
            {
                "name": "Caiyu Chen",
                "org": ""
            },
            {
                "name": "Chuanwei Li",
                "org": ""
            },
            {
                "name": "Na Wang",
                "org": ""
            },
            {
                "name": "Xue Zou",
                "org": ""
            },
            {
                "name": "Xinjian Chen",
                "org": ""
            },
            {
                "name": "Faying Zhou",
                "org": ""
            },
            {
                "name": "Duofen He",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Pedro A. Jose",
                "org": ""
            },
            {
                "name": "Chunyu Zeng",
                "org": ""
            }
        ],
        "title": "Transferred BCR/ABL DNA from K562 extracellular vesicles causes chronic myeloid leukemia in immunodeficient mice",
        "abstract": "Our previous study showed that besides mRNAs and microRNAs, there are DNA fragments within extracellular vesicles (EVs). The BCR/ABL hybrid gene, involved in the pathogenesis of chronic myeloid leukemia (CML), could be transferred from K562 EVs to neutrophils and decrease their phagocytic activity in vitro. Our present study provides evidence that BCR/ABL DNAs transferred from EVs have pathophysiological significance in vivo. Two months after injection of K562 EVs into the tail vein of Sprague-Dawley (SD) rats, they showed some characteristics of CML, e.g., feeble, febrile, and thin, with splenomegaly and neutrophilia but with reduced neutrophil phagocytic activity. These findings were also observed in immunodeficient NOD/SCID mice treated with K562 EVs; BCR/ABL mRNA and protein were found in their neutrophils. The administration of actinomycin D, an inhibitor of de novo mRNA synthesis, prevented the abnormalities caused by K562 EVs in NOD/SCID mice related to CML, including neutrophilia and bone marrow hyperplasia. As a specific inhibitor of tyrosine kinases, imatinib blocked the activity of tyrosine kinases and the expression of phospho-Crkl, induced by the de novo BCR/ABL protein caused by K562 EVs bearing BCR/ABL DNA. Our current study shows the pathophysiological significance of transferred tumor gene from EVs in vivo, which may represent an important mechanism for tumorigenesis, tumor progression, and metastasis. \u00a9 2014 Cai et al.",
        "keywords": [
            ""
        ],
        "venue": "PLoS ONE",
        "year": 2014,
        "id": "rA0epqQm"
    },
    "Y8wkd0q3": {
        "authors": [
            {
                "name": "Nai-Liang Tian",
                "org": "Department of Cardiology"
            },
            {
                "name": "Shao-Liang Chen",
                "org": "Department of Cardiology"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Cardiology"
            },
            {
                "name": "Zhi-Zhong Liu",
                "org": "Department of Cardiology"
            },
            {
                "name": "Fei Ye",
                "org": "Department of Cardiology"
            },
            {
                "name": "Bao-Xiang Duan",
                "org": "Department of Cardiology"
            }
        ],
        "title": "Characteristics of patients with acute inferior wall myocardial infarction spring from different occulded arteries",
        "abstract": "Objective: To study the clinical characteristics of patients with acute inferior wall myocardial infarction spring from different occulded arteries. Method: patients with acute inferior wall myocardial infarction were divided into 2 groups according to coronary angiograms. Group A included 76 patients with right coronary artery occlusion and 24 patients with left circumflex artery occlusion in group B. Their clinical features were studied. Results: On the eectrocardiogram (ECG) the number of ST segment elevation ST",
        "keywords": [
            "Acute inferior wall myocardial infarction",
            "Related infarct coronary artery",
            "ST segment"
        ],
        "venue": "Chinese Journal of Emergency Medicine",
        "year": 2007,
        "id": "Y8wkd0q3"
    },
    "NFBykMzW": {
        "authors": [
            {
                "name": "Minyue Ma",
                "org": "State Key laboratory of Reproductive Biology"
            },
            {
                "name": "Lin Zhou",
                "org": "Laboratory of Reproductive Medicine"
            },
            {
                "name": "Xuejiang Guo",
                "org": "Laboratory of Reproductive Medicine"
            },
            {
                "name": "Zhuo Lv",
                "org": "State Key laboratory of Reproductive Biology"
            },
            {
                "name": "Yang Yu",
                "org": "State Key laboratory of Reproductive Biology"
            },
            {
                "name": "Chenhui Ding",
                "org": "State Key laboratory of Reproductive Biology"
            },
            {
                "name": "Ping Zhang",
                "org": "Laboratory of Reproductive Medicine"
            },
            {
                "name": "Ye Bi",
                "org": "Laboratory of Reproductive Medicine"
            },
            {
                "name": "Jin Xie",
                "org": "Laboratory of Reproductive Medicine"
            },
            {
                "name": "Liu Wang",
                "org": "State Key laboratory of Reproductive Biology"
            },
            {
                "name": "Min Lin",
                "org": "Laboratory of Reproductive Medicine"
            },
            {
                "name": "Zuomin Zhou",
                "org": "Laboratory of Reproductive Medicine"
            },
            {
                "name": "Ran Huo",
                "org": "Laboratory of Reproductive Medicine"
            },
            {
                "name": "Jiahao Sha",
                "org": "Laboratory of Reproductive Medicine"
            },
            {
                "name": "Qi Zhou",
                "org": "State Key laboratory of Reproductive Biology"
            }
        ],
        "title": "Decreased cofilin1 expression is important for compaction during early mouse embryo development",
        "abstract": "Compaction, occurring at the eight-cell stage of mouse development, is the process of cell flattening and polarization by which cellular asymmetry is first established. During this process many molecules and organelles undergo polarized distribution, but the cytoskeletal basis for these distribution specifications remains to be explored. The present study focused on cofilin1, an actin-binding protein that depolymerizes actin filaments. We showed that cofilin1 expression decreased at the compaction stage, and that down-regulation of cofilin1 expression by siRNA microinjection accelerated compaction. Continuous observation using time-lapse video miscroscopy confirmed these findings. That is, the embryonic cells microinjected with anti-cofilin1 antibody exhibit earlier adherence properties compared to uninjected cells. Pronuclear microinjection of a site-directed mutated cofilin1 plasmid, in which cofilin1 is sustained in its active form produced embryos with blastomeres that did not adhere, suggesting that inactivation of cofilin1 is critical for cell flattening and adherence. Fluorescein-phalloidin staining indicated that decreased cofilin1 expression promoted the formation of the apical pole, which is a marker for polarity. Scanning electron microscopy results demonstrated the appearance of microvilli on the outer face of blastomeres in cofilin1 knockdown embryos. Our results suggest that cofilin1 plays an important role in cortical cytoplasmic organization during embryo compaction. \u00a9 2009 Elsevier B.V. All rights reserved.",
        "keywords": [
            "Cofilin1",
            "Compaction",
            "Early development",
            "Embryo",
            "Polarization"
        ],
        "venue": "Biochimica et Biophysica Acta - Molecular Cell Research",
        "year": 2009,
        "id": "NFBykMzW"
    },
    "iw7CM0Gb": {
        "authors": [
            {
                "name": "Cheng Yuan",
                "org": "Department of Respiratory Medicine"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Respiratory Medicine"
            },
            {
                "name": "Jiyun Cheng",
                "org": "Department of Respiratory Medicine"
            },
            {
                "name": "Jingying Zhang",
                "org": "Department of Respiratory Medicine"
            },
            {
                "name": "Yue Teng",
                "org": "Department of Respiratory Medicine"
            },
            {
                "name": "Mao Huang",
                "org": "Department of Respiratory Medicine"
            },
            {
                "name": "Ian M. Adcock",
                "org": "Airway Disease Section"
            },
            {
                "name": "Peter J. Barnes",
                "org": "Airway Disease Section"
            },
            {
                "name": "Xin Yao",
                "org": "Department of Respiratory Medicine"
            }
        ],
        "title": "Statins as potential therapeutic drug for asthma?",
        "abstract": "Background: Statins are lipid-lowering agents that also exhibit pleiotropic effects in decreasing oxidative stress and inflammation. There have been several published studies reporting the use of statins in the treatment of asthma patients, but their results are not consistent. The aim of this study is to determine whether statins are beneficial for asthma administration, and explore the potential covariables that may affect their clinical effectiveness.Methods: A systematic literature search was performed in PubMed, Embase and Cochrane Center Register of Controlled Trials from inception to September 2012. Randomized controlled trials (RCT), retrospective studies and controlled clinical trials which reported the use of statins in the treatment of asthma patients were eligible. Quality evaluation was conducted for RCT using Jadad criteria.Results: A total of 18 articles were included. In our study, we found no conclusive evidence to demonstrate that statins could enhance the lung function in asthmatics, although, they may reduce airway inflammation. Additionally, the results were not consistent across studies with respect to symptoms, quality of life, maintenance medication, asthma hospitalization/emergency department (ED) visits.Conclusions: Statins may reduce airway inflammation in asthmatics, without having a significant effect on lung function. Further large sample and multicenter clinical trials are needed to confirm this and to see if there are more responsive phenotypes of asthma. \u00a9 2012 Yuan et al.; licensee BioMed Central Ltd.",
        "keywords": [
            "Anti-inflammatory",
            "Asthma",
            "Lung function",
            "Statins"
        ],
        "venue": "Respiratory Research",
        "year": 2012,
        "id": "iw7CM0Gb"
    },
    "ljE3LBy6": {
        "authors": [
            {
                "name": "Shao-Liang Chen",
                "org": ""
            },
            {
                "name": "Yao-Jun Zhang",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Du-Jiang Xie",
                "org": ""
            },
            {
                "name": "Feng-Fu Zhang",
                "org": ""
            },
            {
                "name": "Hai-Bo Jia",
                "org": ""
            },
            {
                "name": "Sally S. Wong",
                "org": ""
            },
            {
                "name": "Tak W. Kwan",
                "org": ""
            }
        ],
        "title": "Percutaneous pulmonary artery denervation completely abolishes experimental pulmonary arterial hypertension in vivo",
        "abstract": "Aims: The study sought to assess the effect of percutaneous pulmonary artery denervation (PADN) on bal-loon- occlusion-induced acute pulmonary arterial hypertension (PAH) in vivo. The PADN is a minimally invasive and endovascular catheter-based interventional therapy using radiofrequency ablation to abolish the pulmonary arterial baroreceptors to pressure response. Methods and results: To examine the efficacy of balloon-occlusion-induced PAH, twenty Mongolian dogs were randomly assigned to one of two groups: group 1 (left distal pulmonary basal trunk occlusion) and group 2 (left pulmonary interlobar artery occlusion). Afterwards, PADN treatment at the main pulmonary artery bifurcation level with left pulmonary interlobar artery occlusion in all 20 dogs was conducted. Haemodynamic parameters were measured at baseline and during balloon occlusion as well as the PADN treatment at different time points: one, two, three, five, and ten minutes. Before the PADN treatment, most haemodynamic parameters of the pulmonary artery remained unchanged in group 1 with distal pulmonary basal trunk occlusion. However, in group 2 with the occlusion of the left pulmonary interlobar artery, mean pulmonary arterial pressure, mean right ventricular pressure, and pulmonary vessel resistance gradually increased, and mean absolute difference reached peak at five minutes (\u039416.6 mmHg, \u039414.1 mmHg and \u03941,144 dye/s/cm",
        "keywords": [
            "Denervation",
            "Pulmonary artery",
            "Pulmonary hypertension"
        ],
        "venue": "EuroIntervention",
        "year": 2013,
        "id": "ljE3LBy6"
    },
    "3AqEpTUt": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Reproductive Medicine"
            },
            {
                "name": "Ye Yang",
                "org": "State Key Laboratory of Reproductive Medicine"
            },
            {
                "name": "Juanjuan Zhang",
                "org": "State Key Laboratory of Reproductive Medicine"
            },
            {
                "name": "Xuejiang Guo",
                "org": "State Key Laboratory of Reproductive Medicine"
            },
            {
                "name": "Ye Bi",
                "org": "State Key Laboratory of Reproductive Medicine"
            },
            {
                "name": "Xin Li",
                "org": "State Key Laboratory of Reproductive Medicine"
            },
            {
                "name": "Ping Zhang",
                "org": "State Key Laboratory of Reproductive Medicine"
            },
            {
                "name": "Junqiang Zhang",
                "org": "State Key Laboratory of Reproductive Medicine"
            },
            {
                "name": "Min Lin",
                "org": "State Key Laboratory of Reproductive Medicine"
            },
            {
                "name": "Zuomin Zhou",
                "org": "State Key Laboratory of Reproductive Medicine"
            },
            {
                "name": "Rong Shen",
                "org": "State Key Laboratory of Reproductive Medicine"
            },
            {
                "name": "Xirong Guo",
                "org": "State Key Laboratory of Reproductive Medicine"
            },
            {
                "name": "Ran Huo",
                "org": "State Key Laboratory of Reproductive Medicine"
            },
            {
                "name": "Xiufeng Ling",
                "org": "State Key Laboratory of Reproductive Medicine"
            },
            {
                "name": "Jiahao Sha",
                "org": "State Key Laboratory of Reproductive Medicine"
            }
        ],
        "title": "The Role of RING Box Protein 1 in Mouse Oocyte Meiotic Maturation",
        "abstract": "RING box protein-1 (RBX1) is an essential component of Skp1-cullin-F-box protein (SCF) E3 ubiquitin ligase and participates in diverse cellular processes by targeting various substrates for degradation. However, the physiological function of RBX1 in mouse oocyte maturation remains unknown. Here, we examined the expression, localization and function of RBX1 during mouse oocyte meiotic maturation. Immunofluorescence analysis showed that RBX1 displayed dynamic distribution during the maturation process: it localized around and migrated along with the spindle and condensed chromosomes. Rbx1 knockdown with the appropriate siRNAs led to a decreased rate of first polar body extrusion and most oocytes were arrested at metaphase I. Moreover, downregulation of Rbx1 caused accumulation of Emi1, an inhibitor of the anaphase-promoting complex/cyclosome (APC/C), which is required for mouse meiotic maturation. In addition, we found apparently increased expression of the homologue disjunction-associated protein securin and cyclin B1, which are substrates of APC/C E3 ligase and need to be degraded for meiotic progression. These results indicate the essential role of the SCF",
        "keywords": [
            ""
        ],
        "venue": "PLoS ONE",
        "year": 2013,
        "id": "3AqEpTUt"
    },
    "GLjzjWIT": {
        "authors": [
            {
                "name": "Shanlin Dai",
                "org": ""
            },
            {
                "name": "Kaisheng Yin",
                "org": ""
            },
            {
                "name": "Xin Yao",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            }
        ],
        "title": "Inhibition of interleukin-13 gene expression by triptolide in activated T lymphocytes",
        "abstract": "Background and objective Triptolide, a type of diterpenoid, is the active compound of Tripterygium wilfordii; it plays roles in anti-inflammatory and immune response regulation. Our objective was to investigate the mechanism of the inhibitory effect of triptolide on interleukin-13 (IL-13) gene expression in activated T lymphocytes. Understanding the molecular mechanism by which triptolide exerts a therapeutic function may be useful in developing a pharmaceutical treatment for asthma. Methods Peripheral blood mononuclear cells (PBMC) and Hut-78 cells were stimulated with anti-CD3/CD28 with or without co-incubation with triptolide. The alteration of IL-13 messenger RNA (mRNA), expression and protein level were analysed using real-time reverse transcription polymerase chain reaction (PCR) and enzyme-linked immunosorbent assay, respectively. The intracellular distribution profile of transcription factor GATA3 and nuclear factor of activated T cells (NFAT1) were analysed by Western blotting. The binding rates of GATA3 and NFAT1 to the promoter sequence of IL-13 were analysed by chromatin immunoprecipitation (ChIP) PCR. Results In PBMC, the release of IL-13 was dependent on anti-CD3/CD28 stimulation. Its release could be inhibited by triptolide at the concentration of 500 nmol. In Hut-78 cells, IL-13 mRNA and protein expression were increased with anti-CD3/CD28 stimulation and significantly inhibited by incubation with 28 nmol triptolide. This concentration of triptolide also significantly inhibited the nuclear translocation of GATA3 and NFAT1 reducing the binding rate to the IL-13 gene promoter. Conclusions Triptolide inhibits IL-13 gene transcription and protein expression by inhibiting GATA3 and NFAT1 nuclear translocation and their binding rates to the IL-13 gene promoter region. This study demonstrated that triptolide, an anti-asthma drug from traditional Chinese medicine, could inhibit IL-13 gene transcription and protein expression in activated T cells by inhibiting the nuclear translocation of GATA3 and NFAT1, and decreasing the association of IL-13 gene promoter region with GATA3 or NFAT1. \u00a9 2013 The Authors. Respirology \u00a9 2013 Asian Pacific Society of Respirology.",
        "keywords": [
            "GATA3",
            "interleukin-13",
            "nuclear factor of activated T cells",
            "nuclear translocation",
            "triptolide"
        ],
        "venue": "Respirology",
        "year": 2013,
        "id": "GLjzjWIT"
    },
    "OjJZ8FYA": {
        "authors": [
            {
                "name": "Pei Wang",
                "org": "Department of Reproduction, Nanjing Maternity and Child Health Care Hospital, Nanjing Medical University"
            },
            {
                "name": "Ji Cui",
                "org": "Department of Reproduction, Nanjing Maternity and Child Health Care Hospital, Nanjing Medical University"
            },
            {
                "name": "Chun Zhao",
                "org": "Department of Reproduction, Nanjing Maternity and Child Health Care Hospital, Nanjing Medical University"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Reproduction, Nanjing Maternity and Child Health Care Hospital, Nanjing Medical University"
            },
            {
                "name": "Xirong Guo",
                "org": "Department of Reproduction, Nanjing Maternity and Child Health Care Hospital, Nanjing Medical University"
            },
            {
                "name": "Rong Shen",
                "org": "Department of Reproduction, Nanjing Maternity and Child Health Care Hospital, Nanjing Medical University"
            },
            {
                "name": "Junqiang Zhang",
                "org": "Department of Reproduction, Nanjing Maternity and Child Health Care Hospital, Nanjing Medical University"
            },
            {
                "name": "Xiufeng Ling",
                "org": "Department of Reproduction, Nanjing Maternity and Child Health Care Hospital, Nanjing Medical University"
            }
        ],
        "title": "Differential expression of microRNAs in 2-cell and 4-cell mouse embryos",
        "abstract": "In vitro fertilized (IVF) human embryos have a high incidence of developmental arrest before the blastocyst stage, therefore characterization of the molecular mechanisms that regulate embryo development is urgently required. Post-transcriptional control by microRNAs (miRNAs) is one of the most investigated RNA control mechanisms, and is hypothesized to be involved actively in developmental arrest in preimplantation embryos. In this study, we extracted total RNA from mouse 2-cell and 4-cell embryos. Using a miRNA microarray, 192 miRNAs were found to be differentially expressed in 4-cell embryos and 2-cell embryos; 122 miRNAs were upregulated and 70 were downregulated in 4-cell embryos. The microarray results were confirmed by real-time quantitative RT-PCR for six miRNAs (mmu-miR-467h, mmu-miR-466d-3p, mmu-miR-292-5p, mmu-miR-154, mmu-miR-2145, and mmu-miR-706). Cdca4 and Tcf12 were identified as miR-154 target genes by target prediction analysis. This study provides a developmental map for a large number of miRNAs in 2-cell and 4-cell embryos. The function of these miRNAs and the mechanisms by which they modulate embryonic developmental arrest require further study. The results of this study have potential applications in the field of reproductive medicine.",
        "keywords": [
            "2-cell embryo",
            "4-cell embryo",
            "Developmental arrest",
            "miRNA"
        ],
        "venue": "Zygote",
        "year": 2014,
        "id": "OjJZ8FYA"
    },
    "NJUZ53vq": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Cheng Yuan",
                "org": ""
            },
            {
                "name": "Jingying Zhang",
                "org": ""
            },
            {
                "name": "Rongbin Yu",
                "org": ""
            },
            {
                "name": "Mao Huang",
                "org": ""
            },
            {
                "name": "Ian M. Adcock",
                "org": ""
            },
            {
                "name": "Xin Yao",
                "org": ""
            }
        ],
        "title": "Circulating leptin concentrations in patients with chronic obstructive pulmonary disease: A systematic review and meta-analysis",
        "abstract": "Background: Weight loss is a clinically important risk factor indicating a poor prognosis in chronic obstructive pulmonary disease (COPD). Leptin is an important regulator of food intake and energy expenditure. Objectives: To conduct a meta-analysis to determine whether the level of leptin is related to the disease status of COPD. Methods: Studies published before December 2012 were identified by searching PubMed, Embase and the Cochrane Database. Observational studies comparing circulating leptin levels between COPD patients and healthy controls were included. Data were independently extracted by two investigators and analyzed using Stata 12.0 software. Results: Ten articles were included in the meta-analysis. Circulating leptin levels were correlated with the body mass index (BMI) as well as percent fat mass in stable COPD patients. The correlation coefficient tended to be weaker during exacerbation. A positive correlation between leptin and tumor necrosis factor (TNF)-\u03b1 levels was found in COPD exacerbations, while it disappeared in patients with stable disease. Most studies indicated that circulating leptin levels in stable COPD patients were not significantly different from those in healthy controls when adjusted for gender and BMI, whilst leptin levels tended to elevate in exacerbation groups. Conclusions: The normal regulatory mechanism of leptin is maintained in stable COPD patients despite weight loss. The additional correlation between leptin and TNF-\u03b1 during exacerbations may support the closer association of leptin with changes in nutritional parameters and suggests its valuable role in the evaluation of systemic inflammatory responses in COPD patients during exacerbation, which merits further study. \u00a9 2013 S. Karger AG, Basel.",
        "keywords": [
            "Acute exacerbations",
            "Chronic obstructive pulmonary disease",
            "Circulation",
            "Leptin",
            "Weight loss"
        ],
        "venue": "Respiration",
        "year": 2014,
        "id": "NJUZ53vq"
    },
    "YqenLqP1": {
        "authors": [
            {
                "name": "Xiaojiao Chen",
                "org": "State Key Laboratory of Reproductive Medicine, Department of Reproduction, Nanjing Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University"
            },
            {
                "name": "Junqiang Zhang",
                "org": "Jiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Sciences, Nanjing Normal University"
            },
            {
                "name": "Xun Wu",
                "org": "State Key Laboratory of Reproductive Medicine, Department of Reproduction, Nanjing Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University"
            },
            {
                "name": "Shanren Cao",
                "org": "State Key Laboratory of Reproductive Medicine, Department of Reproduction, Nanjing Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Reproductive Medicine, Department of Reproduction, Nanjing Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University"
            },
            {
                "name": "Ying Wang",
                "org": "State Key Laboratory of Reproductive Medicine, Department of Reproduction, Nanjing Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University"
            },
            {
                "name": "Xin Chen",
                "org": "State Key Laboratory of Reproductive Medicine, Department of Reproduction, Nanjing Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University"
            },
            {
                "name": "Jin Lu",
                "org": "State Key Laboratory of Reproductive Medicine, Department of Reproduction, Nanjing Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University"
            },
            {
                "name": "Chun Zhao",
                "org": "State Key Laboratory of Reproductive Medicine, Department of Reproduction, Nanjing Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University"
            },
            {
                "name": "Minjian Chen",
                "org": "Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University"
            },
            {
                "name": "Xiufeng Ling",
                "org": "State Key Laboratory of Reproductive Medicine, Department of Reproduction, Nanjing Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University"
            }
        ],
        "title": "Trophectoderm morphology predicts outcomes of pregnancy in vitrified-warmed single-blastocyst transfer cycle in a Chinese population",
        "abstract": "Purpose: In this study, we estimated the effect of blastocoele expansion, ICM and TE quality after warming and culture on the rates of clinical pregnancy, live birth and miscarriage in vitrified-warmed single-blastocyst transfer cycle in a Chinese population.",
        "keywords": [
            "Blastocyst grading",
            "Clinical pregnancy",
            "Live birth",
            "Trophectoderm",
            "Vitrified-warmed single-blastocyst transfer"
        ],
        "venue": "Journal of Assisted Reproduction and Genetics",
        "year": 2014,
        "id": "YqenLqP1"
    },
    "mHxSCA1r": {
        "authors": [
            {
                "name": "Ting Lei",
                "org": "Yunnan Metallurgical General Company"
            },
            {
                "name": "Lin Zhou",
                "org": "Research and Development Center"
            },
            {
                "name": "Shuming Fang",
                "org": "Research and Development Center"
            }
        ],
        "title": "Development of a low Ni-Zn white brass",
        "abstract": "The chemical composition of low Ni-Pb-Zn white brass BZn9-39-1 alloy was determined according to the alloying principle of Zn white brass. The property measurement show that the BZn9-39-1 alloy has bi-phase structure and light yellow, exhibiting excellent cold-hot working performance and mechanical properties as well as desirable corrosion resistance and turning ability, which can be suitable for the production of conventional glass frame.",
        "keywords": [
            "Low Ni-Pb-Zn white brass",
            "Properties",
            "Technique"
        ],
        "venue": "Tezhong Zhuzao Ji Youse Hejin/Special Casting and Nonferrous Alloys",
        "year": 2007,
        "id": "mHxSCA1r"
    },
    "PHg6ScqB": {
        "authors": [
            {
                "name": "Fengxia Han",
                "org": ""
            },
            {
                "name": "Ting Lei",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Shihong Huang",
                "org": ""
            },
            {
                "name": "Gaigai L\u00fc",
                "org": ""
            }
        ],
        "title": "Ratio of anthracite to ilmenite of titanium slag smelted by 30 MVA DC arc furnace",
        "abstract": "The adequate carbon should be fed as reductant in order to achieve qualified titanium slag, and deoxidized the highoxide to lowoxide. The domestic first 30 MVA DC arc furnace of a company in Yunnan province obtained the favorable slag by controlling the ratio of anthracite to ilmenite (AIR), in the case of certain energy input and stable component of ilmenite. The ilmenite and anthracite were put into DC furnace through hollow graphite electrode, meanwhile it was needed to control temperature between 1973 K and 2023 K, 15 MVA of input power, 0.1~0.33 mm of partical size of ilmenite, the ratio of anthracite partical size range of 5~25 mm were more than 85%. Theoretically, deoxidizing 1t ilmenite would produce 526 kg titanium slag and 368 kg iron, and Output/Input rate was about 89.4%, the theory AIR was about 7.895%. Calculated on mass balance, the mean AIR during the smelting period was 12.228%, and output/input rate was 81.317%. With the short of anthracite, the oxygen of FeO in ilmenite would be easy to dissociate and combine with carbon; in this case, the reduction reaction of FeO would be prior to TiO ",
        "keywords": [
            "Carbon reduction",
            "Direct current electric arc furnace",
            "Ilmenite",
            "Ratio of anthracite to ilmenite",
            "Titanium slag"
        ],
        "venue": "Xiyou Jinshu/Chinese Journal of Rare Metals",
        "year": 2012,
        "id": "PHg6ScqB"
    },
    "jfMTUDDY": {
        "authors": [
            {
                "name": "Fengxia Han",
                "org": ""
            },
            {
                "name": "Ting Lei",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            }
        ],
        "title": "Energy balance and offgas utilization of ilmenite smelting in a 30 MVA direct current electric arc furnace",
        "abstract": "Energy balance and offgas utilization of ilmenite smelting in 30 MVA direct current electric arc furnace (DC furnace) of a Yunnan company were investigated to make sure safety production, and to save energy and reduce pollution. The total input energy in the DC furnace was 2,000 kWh per ton of ilmenite, in which 1,003.31 kWh per ton of ilmenite was used to carbothermic reduction and other energy was consumed as heatloss. Based on energy conservation, the whole system heatloss in physical production should be controlled at 1,000 kWh per ton of ilmenite. With high combustion heat, the offgas discharged from furnace after treatment could be used to ilmenite drying, anthracite drying, titanium slag drying, and casting ladle baking. The offgas design flow ranged from 5,000 to 8,000 Nm ",
        "keywords": [
            "Direct current electric arc furnace",
            "Energy balance",
            "Ilmenite",
            "Offgas",
            "Titanium slag"
        ],
        "venue": "Advanced Materials Research",
        "year": 2012,
        "id": "jfMTUDDY"
    },
    "kGveZnIv": {
        "authors": [
            {
                "name": "Shihong Huang",
                "org": "Faculty of Metallurgical and Energy Engineering, Kunming University of Science and Technology"
            },
            {
                "name": "Ting Lei",
                "org": "Kunming Metallurgy College"
            },
            {
                "name": "Fengxia Han",
                "org": "Quality Development Institute, Kunming University of Science and Technology"
            },
            {
                "name": "Lin Zhou",
                "org": "Technology Center, Yunnan Metallurgy Group Co. Ltd."
            }
        ],
        "title": "Element distribution of titanium slag smelted by DC arc furnace",
        "abstract": "Based on chemical equilibrium calculation method in multi-phase, multi-component system, the distribution behavior of titanium, carbon and associated elements during the smelting process was studied. The calculated results agreed well with the experimental results. The effect of AIR (anthracite to ilmenite ratio) on the distribution of Ti, C, Ca, Mg, Si and Al in slag and metal was analyzed. The results showed that AIR was a significant factor. With the increase of AIR, the mass fraction of TiO",
        "keywords": [
            "Element distribution",
            "Ilmenite",
            "Smelting reduction process",
            "Titanium slag"
        ],
        "venue": "Xiyou Jinshu/Chinese Journal of Rare Metals",
        "year": 2014,
        "id": "kGveZnIv"
    },
    "0ENTFUaq": {
        "authors": [
            {
                "name": "Shihong Huang",
                "org": ""
            },
            {
                "name": "Ting Lei",
                "org": ""
            },
            {
                "name": "Fengxia Han",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            }
        ],
        "title": "Effect of ilmenite component and AIR on element distribution of titanium slag smelted by DC arc furnace",
        "abstract": "Based on chemical equilibrium calculation method in multi-phase, multi-component system, the effects of ilmenite component (TiO",
        "keywords": [
            "Element distribution",
            "Smelting reduction process",
            "Titanium slag"
        ],
        "venue": "Xiyou Jinshu Cailiao Yu Gongcheng/Rare Metal Materials and Engineering",
        "year": 2014,
        "id": "0ENTFUaq"
    },
    "COqkPUIx": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Department of Landscape Architecture"
            },
            {
                "name": "Peiyi Jia",
                "org": "Department of Landscape Architecture"
            },
            {
                "name": "Wenwen Guo",
                "org": "Department of Landscape Architecture"
            },
            {
                "name": "Lianying Wang",
                "org": "Department of Landscape Architecture"
            },
            {
                "name": "Li Dong",
                "org": "Department of Landscape Architecture"
            }
        ],
        "title": "Effect of different storage temperatures on postharvest quality of cut flowers of tree peony 'Luo Yang Hong'",
        "abstract": "Tree peony (Paeonia suffruticosa) cut flowers are well known in China and have high potential market value. A large production base of tree peony grown for cut flowers has been built in China, but many postharvest handling problems exist, and optimum conditions for long term storage and transportation have yet to be determined. In order to identify the most suitable storage conditions and to better understand the mechanism of postharvest senescence of tree peony cut flowers, the effects of different storage temperatures on postharvest quality and physiological changes in cut flowers of tree peony 'Luo Yang Hong' were investigated. Branches with flowers at the bud stage were dry-stored at two temperatures of T1 (2\u00b12\u00b0C) and T2 (6\u00b12\u00b0C) for 49 d. During storage, flowers were removed at 7-day intervals to measure vase life, flower opening index, fresh weight loss, electrical conductivity (EC) and malondialdehyde (MDA) content. Flowers stored at T1 or T2 for 7 d maintained a post-storage vase life of more than 5 d, which was similar to that of non-stored (control) cut flowers, while those stored at T1 or T2 for periods of 14 or more days suffered significant loss in vase life. Flowers stored at T1 from 21-days had a longer vase life, and were able to open normally even after 49-days storage, than flowers stored at T2 that were unable to open normally after 35-days storage. The better postharvest quality achieved at lower storage temperature was associated with less fresh weight loss and lower EC and MDA content in cut flower petals.",
        "keywords": [
            "Cut flower",
            "EC",
            "MDA",
            "Paeonia suffruticosa",
            "Storage temperature"
        ],
        "venue": "Acta Horticulturae",
        "year": 2008,
        "id": "COqkPUIx"
    },
    "pJ8gcKFj": {
        "authors": [
            {
                "name": "Peiyi Jia",
                "org": "Department of Landscape Architecture"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Landscape Architecture"
            },
            {
                "name": "Wenwen Guo",
                "org": "Department of Landscape Architecture"
            },
            {
                "name": "Lianying Wang",
                "org": "Department of Landscape Architecture"
            },
            {
                "name": "Li Dong",
                "org": "Department of Landscape Architecture"
            }
        ],
        "title": "Postharvest behavior and endogenous ethylene pattern of Paeonia suffruticosa cut flowers",
        "abstract": "Thirteen cultivars of tree-peony were chosen as material to investigate changes of postharvest behavior and endogenous ethylene concentrations during opening and senescence of flowers. The flower opening index, diameter, senescence characters, ethylene production during opening, and senescence during vase life of cut flowers were investigated to elucidate the basic behavior and the postharvest pattern of endogenous ethylene production of t tree peony cut flowers. There were significant differences in ethylene production between the different cultivars and the 13 cultivars could be classified into 3 groups: (1) For 'Luo Yang Hong', 'Ru Hua Si Yu', 'Bai Hua Cong Xia', 'Ceng Zhong Xiao', 'Chun Hong Jiao Yan', and 'Yu Mian Tao Hua', ethylene production increased gradually during opening and reached a peak at the full open phase, then decreased. This pattern was similar to that in climacteric cut flowers and fruits. (2) For 'Tai Ping', 'Xue Ying Tao Hua', 'Rou Fu Rong', and 'Shi Ba Hao', ethylene production decreased or remained at a relatively stable level from opening to senescence. This pattern was similar to that in nonclimacteric cut flowers. (3) Ethylene production of 'Xue Lian' and 'Ying Ri Hong' cut flowers increased during opening and reached a peak at senescence. This pattern was similar to the ethylene increase during later stages cut flowers and fruits. Similar patterns were also found in flowers that opened naturally; however, for 'Luo Yang Hong', 'Bai Hua Cong Xia', and 'Yu Mian Tao Hua' were assorted to totally different types in the different opening conditions.",
        "keywords": [
            "Ethylene metabolism",
            "Opening and senescence",
            "Tree-peony cut flowers"
        ],
        "venue": "Acta Horticulturae",
        "year": 2008,
        "id": "pJ8gcKFj"
    },
    "P0dcWvOE": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Department of Landscape Architecture"
            },
            {
                "name": "Peiyi Jia",
                "org": "Department of Landscape Architecture"
            },
            {
                "name": "Wenwen Guo",
                "org": "Department of Landscape Architecture"
            },
            {
                "name": "Lianying Wang",
                "org": "Department of Landscape Architecture"
            },
            {
                "name": "Dong Li",
                "org": "Department of Landscape Architecture"
            }
        ],
        "title": "Influence of ethylene on postharvest behavior of 'luo yang hong' tree peony cut flower",
        "abstract": "'Luo Yang Hong' tree peony is a suitable cultivar for exploitation as a cut flower and a former study has indicated that its flower opening and senescence process is associated with endogenous ethylene production. Tree peony (Paeonia suffruticosa) 'Luo Yang Hong' cut branches with flowers at the bud stage were treated with exogenous ethylene and the ethylene action inhibitor, silver thiosulphate (STS) respectively, to examine the influence of ethylene on their postharvest behavior. In contrast with control flowers, the opening process of both types of treated flowers were significantly accelerated, however their vase life was not affected. Control cut flowers produced ethylene in a climacteric-like pattern. Ethylene and STS treatment restrained the peak value of ethylene production, however, no apparent difference of the trend of ethylene production between the treated and control flowers was shown. These results suggest that the responses of postharvest behavior of tree peony cut flowers to ethylene do not show the representative characteristics of climacteric flowers, and are worthy for further study.",
        "keywords": [
            "Cut flower",
            "Ethylene",
            "Ethylene production",
            "Flower opening and senescence",
            "Paeonia suffruticosa",
            "Silver thiosulphate"
        ],
        "venue": "Acta Horticulturae",
        "year": 2008,
        "id": "P0dcWvOE"
    },
    "S7p0z6ft": {
        "authors": [
            {
                "name": "Lei Sun",
                "org": "Department of Ornamental Horticulture"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Ornamental Horticulture"
            },
            {
                "name": "Miao Lu",
                "org": "Department of Ornamental Horticulture"
            },
            {
                "name": "Ming CAI",
                "org": "Department of Ornamental Horticulture"
            },
            {
                "name": "Xi-Wang Jiang",
                "org": "Department of Ornamental Horticulture"
            },
            {
                "name": "Qi-Xiang Zhang",
                "org": "Department of Ornamental Horticulture"
            }
        ],
        "title": "Marker-Free Transgenic Chrysanthemum obtained by Agrobacterium-mediated transformation with twin T-DNA binary Vectors",
        "abstract": "In this study, a superbinary vector was constructed to evaluate the potential of a twin T-DNA system for generating selectable marker-free transgenic chrysanthemum plants. The first T-DNA of the pCAMBIA 1300 vector contained the hygromycin phosphotransferase (hpt) selectable marker gene, while the second T-DNA carried the \u03b2-glucuronidase gene (uidA) and featuring the gene of interest. The two T-DNA regions were placed adjacent to each other with no intervening region. This vector was then used to transform transversal thin cell layers (1-2 mm thick) of internodal stem segments of chrysanthemum via Agrobacterium-mediated transfer. Putative transgenic plants were obtained and analyzed for presence and integration of the transgene using polymerase chain reaction amplification and Southern blotting. The primary cotransformation frequency was calculated at 38.4%. A total of 17 hpt-resistant/gus-positive T0 plants were evaluated for segregation in the next generation (T1), and among those approximately 15.7% carried the transgene. Overall, the two T-DNA system appeared to be a useful approach to generate marker-free transgenic chrysanthemum plants, thereby eliminating public concerns regarding proliferation of antibiotic and herbicide resistance genes into the environment. \u00a9 Springer-Verlag 2008.",
        "keywords": [
            "Cotransformation",
            "Gene modified plants",
            "Nonselective marker"
        ],
        "venue": "Plant Molecular Biology Reporter",
        "year": 2009,
        "id": "S7p0z6ft"
    },
    "BH94phyI": {
        "authors": [
            {
                "name": "Peiyi Jia",
                "org": "Department of Landscape Architecture"
            },
            {
                "name": "Li Dong",
                "org": "Department of Landscape Architecture"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Landscape Architecture"
            }
        ],
        "title": "Responses of tree-peony cultivars to exogenous ethylene and 1-MCP",
        "abstract": "Different types of cultivars including 'Luo Yang Hong' which presents an ethylene burst and 'Xue Ying Tao Hua' which keeps a relatively low and stable ethylene production during postharvest opening and senescence were chosen to investigate the responses of their postharvest behavior and ethylene related enzymes activity to continuous exposure to the exogenous ethylene and its action inhibitor, 1-MCP. The effects of 12, 24, 36, 48, 60 and 72 h treatment with 10 \u03bcl L",
        "keywords": [
            "Ethylene biosynthesis related enzyme",
            "Opening and senescence",
            "Tree-peony cut flowers"
        ],
        "venue": "Acta Horticulturae",
        "year": 2009,
        "id": "BH94phyI"
    },
    "3mpns354": {
        "authors": [
            {
                "name": "Chun-Yan Lv",
                "org": "Research Institute of Forestry"
            },
            {
                "name": "Yan Wang",
                "org": "Research Institute of Forestry"
            },
            {
                "name": "Xiang-Tao Zhu",
                "org": "Research Institute of Forestry"
            },
            {
                "name": "Lin Zhou",
                "org": "Research Institute of Forestry"
            },
            {
                "name": "Bao-Qiang Zheng",
                "org": "Research Institute of Forestry"
            }
        ],
        "title": "Comparison of methods about Paeonia lutea' s pollen viability determination",
        "abstract": "The fresh pollen of Paeonia lutea was employed as experimental material to study the pollen viability. The effects of different concentration of sucrose, boron, calcium, magnesium and potassium on the germination of P. lutea' a pollen were compared through simple factorial experiment. Based on these, the orthogonal design was used to compare the effects of sucrose, boron and calcium on the germination of P. lutea ' s pollen. Carmine acetate staining, I ",
        "keywords": [
            "Determination method",
            "Paeonia lutea",
            "Pollen",
            "Viability"
        ],
        "venue": "Forest Research",
        "year": 2010,
        "id": "3mpns354"
    },
    "RsbEjpRf": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Tree Breeding and Cultivation"
            },
            {
                "name": "Li Dong",
                "org": "Department of Landscape Architecture"
            },
            {
                "name": "Pei-Yi Jia",
                "org": "Department of Landscape Architecture"
            },
            {
                "name": "Wei-Ran Wang",
                "org": "Department of Landscape Architecture"
            },
            {
                "name": "Lian-Ying Wang",
                "org": "Department of Landscape Architecture"
            }
        ],
        "title": "Expression of ethylene receptor and transcription factor genes, and ethylene response during flower opening in tree peony (Paeonia suffruticosa)",
        "abstract": "Tree peony (Paeonia suffruticosa) is a well known traditional ornamental plant in China and cut flowers of tree peony have potential market value. To understand the involvement of ethylene in the cut flowers opening at the transcription level of ethylene signaling, we isolated two partial cDNAs encoding ethylene receptor Ps-ETR1-1 (GenBank accession no. EU526838) and transcription factor Ps-EIN3-1 (GenBank accession no. EU526839) from tree peony flower petals, and studied the effects of exogenous ethylene and 1-methylcyclopropene (1-MCP), an ethylene action inhibitor, on the expression of Ps-ETR1-1 and Ps-EIN3-1 during vase life. Northern blot analysis revealed that Ps-ETR1-1 and Ps-EIN3-1 exhibited constitutive levels during untreated flower opening, and they responded significantly to ethylene and 1-MCP treatments. In contrast with the control, the levels of Ps-ETR1-1 mRNA in petals were substantially inhibited by both ethylene and 1-MCP, and remained at nearly unchangeable level throughout flower development. Expression of Ps-EIN3-1 was strongly inhibited by ethylene and slightly induced by 1-MCP during flower opening and senescence. These results suggest that the Ps-ETR1-1 and Ps-EIN3-1 genes and their resultant protein may be involved in the ethylene sensitivity and responses of tree peony cut flowers. \u00a9 2010 Springer Science+Business Media B.V.",
        "keywords": [
            "Ethylene receptor",
            "Flower opening",
            "Gene expression",
            "Transcription factor",
            "Tree peony (Paeonia suffruticosa)"
        ],
        "venue": "Plant Growth Regulation",
        "year": 2010,
        "id": "RsbEjpRf"
    },
    "Nk8CeGfW": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Tree Breeding and Cultivation"
            },
            {
                "name": "Yan Wang",
                "org": "Key Laboratory of Tree Breeding and Cultivation"
            },
            {
                "name": "Zhenhua Peng",
                "org": "Key Laboratory of Tree Breeding and Cultivation"
            }
        ],
        "title": "Molecular characterization and expression analysis of chalcone synthase gene during flower development in tree peony (paeonia suffruticosa)",
        "abstract": "Chalcone synthase (CHS, EC: 2.3.1.74) is a key enzyme in the flavonoid and anthocyanin biosynthesis pathway. In order to investigate the role of CHS in tree peony flower coloration mechanism, we isolated and characterized the CHS gene from Paeonia suffruticosa cv. Yu Ji Yan Zhuang and analyzed its spatial and temporal expression patterns during floral development. The cDNA sequence of the CHS gene in P. suffruticosa (Ps-CHS1, genbank accession no. GQ483511) was 1475 bp in full length containing an opening reading frame (ORF) of 1185 bp that encoded a 394 amino acid polypeptide. Bioinformatic analysis showed that, Ps-CHS1 possessed all the conserved active sites for the CHS function as well as the family signature. Sequence alignment and phylogenetic analysis revealed that Ps-CHS1 shared high homology with CHS from plants in Salicaceae, Malvaceae and Rosaceae. The homology-based structural modeling showed that Ps-CHS1 had the typical structure of CHS. Southern blot analysis indicated that CHS was encoded by a small multigene family in the genome of tree peony. Anthocyanidin content in full-opening flower petals accumulated to the highest level. Real-time polymerase chain reaction amplification (PCR) analysis indicated that, Ps-CHS1 showed the highest transcript abundance in petals, moderate levels in sepals, low levels in leaves and stamens, and the lowest levels in carpels. Ps-CHS1 was actively expressed during flower development and increased gradually until reached maximal expression when flower fully opened. These results indicated that Ps- CHS1 was involved in the flower pigmentation of tree peony. \u00a9 2011 Academic Journals.",
        "keywords": [
            "Anthocyanin",
            "Chalcone synthase",
            "Expression",
            "Tree peony (paeonia suffruticosa)"
        ],
        "venue": "African Journal of Biotechnology",
        "year": 2011,
        "id": "Nk8CeGfW"
    },
    "CHZ94Esp": {
        "authors": [
            {
                "name": "Qian-Qian Shi",
                "org": "State Key Laboratory of Forest Genetics and Tree Breeding"
            },
            {
                "name": "Yan Wang",
                "org": "State Key Laboratory of Forest Genetics and Tree Breeding"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Forest Genetics and Tree Breeding"
            },
            {
                "name": "Guo-Wei Huang",
                "org": "State Key Laboratory of Forest Genetics and Tree Breeding"
            }
        ],
        "title": "Karyotypes and chromosomal differentiation in cultivars of tree peony (Paeonia suffruticosa)",
        "abstract": "30 traditional cultivars of Paeonia suffruticosa with 10 different colors were selected as materials, and the squash method was used to analyze the features of chromosome. According to Stebbins theory of karyotypic evolution as well as using the method of coding of cladistics, 4 significant characters were analyzed. The results suggested that all the materials were diploid, 2n=10; the karyotypes mostly were 2A, and most was primitive type; the karyotype formulas mostly were 2n=6m+2sm+2st. The chromosomal differentiation of 'Yin Fen Jin Lin', 'Luo Yang Hong' and 'Ying Luo Bao Zhu' was high, and that of 'Gong Yang Zhuang', 'Yi Pin Zhu Yi' and 'Chi Long Huan Cai' was low. The importance of karyotype parameters was A. A. R>A.sk%>Lt/St>P.C.A%. The karyotypes were similar among different flower colors. The cultivars of the same color system had similar evolution levels, and the darker colors were more evolutional than the lighter ones. This research could provide some references for the study on evolution of traditional cultivars of P. suffruticosa.",
        "keywords": [
            "Color",
            "Evolution",
            "Karyotype",
            "Paeonia suffruticosa"
        ],
        "venue": "Forest Research",
        "year": 2012,
        "id": "CHZ94Esp"
    },
    "X6cm2w8c": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Tree Genetics and Breeding, Research Institute of Forestry"
            },
            {
                "name": "Chao Zhang",
                "org": "Department of Landscape Architecture"
            },
            {
                "name": "Jianxin Fu",
                "org": "Department of Landscape Architecture"
            },
            {
                "name": "Miao Liu",
                "org": "Department of Landscape Architecture"
            },
            {
                "name": "Yuhuan Zhang",
                "org": "Department of Landscape Architecture"
            },
            {
                "name": "Yanjie Wang",
                "org": "Department of Landscape Architecture"
            },
            {
                "name": "Li Dong",
                "org": "Department of Landscape Architecture"
            }
        ],
        "title": "Molecular Characterization and Expression of Ethylene Biosynthetic Genes During Cut Flower Development in Tree Peony (Paeonia suffruticosa) in Response to Ethylene and Functional Analysis of PsACS1 in Arabidopsis thaliana",
        "keywords": [
            "Ethylene biosynthetic genes",
            "Expression",
            "Flower opening and senescence",
            "Transgenic Arabidopsis",
            "Tree peony"
        ],
        "venue": "Journal of Plant Growth Regulation",
        "year": 2013,
        "id": "X6cm2w8c"
    },
    "ljM46if6": {
        "authors": [
            {
                "name": "Kui Li",
                "org": "State Key Laboratory of Tree Genetics and Breeding"
            },
            {
                "name": "Bao Qiang Zheng",
                "org": "State Key Laboratory of Tree Genetics and Breeding"
            },
            {
                "name": "Yan Wang",
                "org": "State Key Laboratory of Tree Genetics and Breeding"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Tree Genetics and Breeding"
            }
        ],
        "title": "Breeding system and pollination biology of Paeonia delavayi (Peaoniaceae), an endangered plant in the Southwest of China",
        "abstract": "Breeding system and pollination biology of Paeonia delavayi (Peaoniaceae) from Shangri-La, Yunnan Province, southwest of China were studied. Flowering phenologies and flower visitors were observed or collected from 2008 to 2011. The pollen viability, stigma receptivity and pollination efficiency of different visitors were detected and tested. The florescence lasted for 6- 9d in a single flower from mid-May to late June. A high percentage of flower damage promoted early anther dehiscence. Flowers started disseminating pollen at 1-2 d after flowering, and lasted for 5-6 d. Pollen viability could be preserved for more than 10 d at normal temperature. High seed rate from the stigma was observed at 1 d before flowering to 3d after flowering, and the dissemination hysteresis was defined as protogyny. The P/O ratios were 6,124 to 9,713:1, suggesting that the larger quantity of pollen to increased the seed setting rate. Three species of bees, eight species of beetles, seven species of syrphid flies, four species of ants, and three species of butterflies were observed on the flowers. P. delavayi rewarded to the visitors by releasing fragrance, providing pollen and nectar. On the bodies of the visitors under stereomicroscope and scanning electron microscope (SEM), much pollen from the plants of similar flowering period inner community were found which indicated that these incompatible visitors were not species-specific pollinators. The bagging experiments showed that P. delavayi was selfincompatible and no apomixes. Anemophily only played a minor role in the fertilization. A few seeds with poor plumpness can be produced by geitonogamy. Seed setting rate of artificial xenogamy was higher than natural pollination. Artificial control of the visitors\u2019 species showed bees being the most important pollinators. Beetles and ants participated in pollination to some extent and were unstable. Syrphid flies and butterflies were very unreliable with low pollination efficiency. Reproductive success depended largely on cross-pollination assisted by pollinator activities, especially the bees.",
        "keywords": [
            "Ants",
            "Bees",
            "Beetles",
            "Breeding system",
            "Endangered plant",
            "Flowering time",
            "P/O ratio",
            "Paeonia delavayi",
            "Pollination biology",
            "Stigma receptivity"
        ],
        "venue": "Pakistan Journal of Botany",
        "year": 2014,
        "id": "ljM46if6"
    },
    "ktviI4rt": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Yan Wang",
                "org": ""
            },
            {
                "name": "Lei Ren",
                "org": ""
            },
            {
                "name": "Qianqian Shi",
                "org": ""
            },
            {
                "name": "Baoqiang Zheng",
                "org": ""
            },
            {
                "name": "Kun Miao",
                "org": ""
            },
            {
                "name": "Xin Guo",
                "org": ""
            }
        ],
        "title": "Overexpression of Ps-CHI1, a homologue of the chalcone isomerase gene from tree peony (Paeonia suffruticosa), reduces the intensity of flower pigmentation in transgenic tobacco",
        "abstract": "Chalcone isomerase (CHI) is one of the key enzymes in the flavonoid and anthocyanin biosynthesis pathway catalyzing the stereospecific isomerization of chalcones into their corresponding (2S)-flavanones. In this study, to investigate the role of CHI in tree peony flower coloration mechanism, a CHI gene was isolated from Paeonia suffruticosa cv. Guan Shi Mo Yu, and designated as Ps-CHI1. The cDNA sequence of Ps-CHI1 was 924 bp in full length containing an opening reading frame of 654 bp that encoded a peptide of 217 amino acids with a predicted molecular mass of 23.3 kDa and a pI of 5.0. Sequence alignment and phylogenetic analysis revealed that Ps-CHI1 shared high homology with other type I higher plant CHI proteins. Quantitative real-time PCR analysis indicated that Ps-CHI1 showed the highest transcript abundance in petals, moderate levels in sepals, low levels in leaves and carpels and the lowest levels in stamens. Ps-CHI1 was expressed at the highest level in early stage of uncolored flowers and underwent moderate decreases in expression until there was little transcription could be detected when flowers fully opened and deeply pigmented. By inserting Ps-CHI1 into tobacco (Nicotiana tabacum L.) via Agrobacterium-mediated transformation, T",
        "keywords": [
            "Chalcone isomerase",
            "Gene expression",
            "Molecular cloning",
            "Transgenic tobacco",
            "Tree peony (Paeonia suffruticosa)"
        ],
        "venue": "Plant Cell, Tissue and Organ Culture",
        "year": 2014,
        "id": "ktviI4rt"
    },
    "QShgv21T": {
        "authors": [
            {
                "name": "Qian-Qian Shi",
                "org": "Key Laboratory of Tree Breeding and Cultivation, Research Institute of Forestry, Chinese Academy of Forestry"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Tree Breeding and Cultivation, Research Institute of Forestry, Chinese Academy of Forestry"
            },
            {
                "name": "Kui Li",
                "org": "Key Laboratory of Tree Breeding and Cultivation, Research Institute of Forestry, Chinese Academy of Forestry"
            },
            {
                "name": "Yan Wang",
                "org": "Key Laboratory of Tree Breeding and Cultivation, Research Institute of Forestry, Chinese Academy of Forestry"
            }
        ],
        "title": "Transcriptional regulation involved in anthocyanin biosynthesis in plants",
        "abstract": "Anthocyanin is a kind of secondary products during the process of flavonoid metabolizing and determine the colors of flowers, fruits and seeds. With the research on flavonoids biosynthesis, many structural genes synthesized anthocyanins of various plants have been cloned, and the previous studies showed that the structural genes were activated by transcription factors (MYB, bHLH and WD40) with complex interaction patterns. In this paper, MYB transcription factors, bHLH transcription factors and WD40 repeat protein involved in anthocyanin biosynthesis and their roles in the regulation of structural gene expression and anthocyanin synthesis are reviewed.",
        "keywords": [
            "Anthocyanin",
            "BHLH",
            "MYB",
            "Transcription factor",
            "WD40"
        ],
        "venue": "Forest Research",
        "year": 2015,
        "id": "QShgv21T"
    },
    "TNrydhjs": {
        "authors": [
            {
                "name": "Shi-Ming Cheng",
                "org": ""
            },
            {
                "name": "Yu-Ji Lai",
                "org": ""
            },
            {
                "name": "Er-Yong Liu",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Xue-Jing Wang",
                "org": ""
            },
            {
                "name": "Qiu-Lan Chen",
                "org": ""
            },
            {
                "name": "Dong-Ming Li",
                "org": ""
            },
            {
                "name": "Ning Wang",
                "org": ""
            }
        ],
        "title": "Study on factors affecting TB/HIV co-infection in four counties of China",
        "abstract": "The factors affecting case detection of tuberculosis (TB)/human immunodeficiency virus (HIV) co-infection cases were explored in order to provide evidence-based formulation of a TB/HIV co-infection control strategy in China. Four counties with different modes of HIV transmission and varying cooperation mechanisms between TB and HIV institutions were selected. HIV test among TB patients and TB examination among people living with HIV/acquired immunodeficiency syndrome (AIDS) were conducted. Patients also completed questionnaires on potential factors affecting TB/HIV co-infection. The results showed that 19 (1.7%) were HIV-positive among 1089 cases of people living with active TB who received HIV testing. Conversely, there were 126 (10%) cases of active TB among 1255 cases of people living with HIV/AIDS. Among the newly discovered 145 cases of TB/HIV co-infection, AIDS institutions found 86.9% of these co-infections and 14.1% came from TB institutes. In different registration categories, there were 31 (21.4%) cases of smear positive TB, 104 (71.7%) cases of smear negative TB, and extrapulmonary cases accounted for 10 (6.9%). Gender, occupation, marital status, ethnic group, education, HIV transmission route, CD4 level, and type of TB susceptible symptoms had significant effects on whether HIV/AIDS patients were co-infected with TB disease (P < 0.01). Sex, age, ethnic group, occupation, and type of tuberculosis had no significant influence on whether TB patients had HIV infection. AIDS institutions could find more TB/HIV co-infection patients in comparison with TB institutions, particularly in patients with smear negative pulmonary tuberculosis and extrapulmonary tuberculosis. Therefore, a cooperation mechanism should be built up between TB and HIV control systems, and routine TB checks should be conducted for HIV/AIDS patients. In areas where sex or drug use is the major transmission mode of HIV infection, antiretroviral therapy should be expanded, treatment adherence should be improved and patients' immunity level should be increased in order to decrease TB incidence. Cough and expectoration of more than two weeks, bloody sputum, and recurrent fevers could be revealing symptoms in TB screening of HIV/AIDS patients. \u00a9 2010 Higher Education Press and Springer-Verlag Berlin Heidelberg.",
        "keywords": [
            "Case detection",
            "Dual infection",
            "Impact factors",
            "Prevention and control",
            "Tuberculosis/acquired immunodeficiency syndrome"
        ],
        "venue": "Frontiers of Medicine in China",
        "year": 2010,
        "id": "TNrydhjs"
    },
    "CJ6HO6j1": {
        "authors": [
            {
                "name": "Yin Yin Xia",
                "org": "Department of Epidemiology and Biostatistics"
            },
            {
                "name": "Dai Yu Hu",
                "org": "Center for Disease Control and Prevention in Chongqing Municipality"
            },
            {
                "name": "Fei Ying Liu",
                "org": "Center for Disease Control and Prevention in Guangxi Zhuang Autonomous Region"
            },
            {
                "name": "Xiao Meng Wang",
                "org": "Center for Disease Control and Prevention in Zhejiang Province"
            },
            {
                "name": "Yan Li Yuan",
                "org": "Center for Disease Control and Prevention in Jilin Province"
            },
            {
                "name": "De Hua Tu",
                "org": "Beijing Institute for Tuberculosis Control"
            },
            {
                "name": "Yi Xin Chen",
                "org": "Center for Drug Reassessment"
            },
            {
                "name": "Lin Zhou",
                "org": "Center for Tuberculosis Control and Prevention"
            },
            {
                "name": "Li Zhen Zhu",
                "org": "Beijing Tuberculosis and Thoracic Tumor Research Institute"
            },
            {
                "name": "Wei Wei Gao",
                "org": "Beijing Tuberculosis and Thoracic Tumor Research Institute"
            },
            {
                "name": "Hong Yuan Wang",
                "org": "Department of Epidemiology and Biostatistics"
            },
            {
                "name": "Da Fang Chen",
                "org": "Department of Epidemiology and Biostatistics"
            },
            {
                "name": "Li Yang",
                "org": "Department of Health Policy and Management"
            },
            {
                "name": "Ping Ping He",
                "org": "Department of Epidemiology and Biostatistics"
            },
            {
                "name": "Xiao Ting Li",
                "org": "Department of Epidemiology and Biostatistics"
            },
            {
                "name": "Ying Jian He",
                "org": "Department of Epidemiology and Biostatistics"
            },
            {
                "name": "Feng Sun",
                "org": "Department of Epidemiology and Biostatistics"
            },
            {
                "name": "Si Yan Zhan",
                "org": "Department of Epidemiology and Biostatistics"
            }
        ],
        "title": "Design of the anti-tuberculosis drugs induced adverse reactions in China national tuberculosis prevention and control scheme study (ADACS)",
        "abstract": "Background. More than 1 million tuberculosis (TB) patients are receiving the standard anti-TB treatment provided by China National Tuberculosis Prevention and Control Scheme (CNTS) in China every year. Adverse reactions (ADRs) induced by anti-TB drugs could both do harm to patients and lead to anti-TB treatment failure. The ADACS aimed to explore ADRs' incidences, prognoses, economical and public health impacts for TB patients and TB control, and build a DNA bank of TB patients. Methods/Design. Multiple study designs were adopted. Firstly, a prospective cohort with 4488 sputum smears positive pulmonary tuberculosis patients was established. Patients were followed up for 6-9 months in 52 counties of four regions. Those suspected ADRs should be checked and confirmed by Chinese State Food and Drug Administration (SFDA). Secondly, if the suspected ADR was anti-TB drug induced liver injury (ATLI), a nested case-control study would be performed which comprised choosing a matched control and doing a plus questionnaire inquiry. Thirdly, health economical data of ADRs would be collected to analyze financial burdens brought by ADRs and cost-effectiveness of ADRs' treatments. Fourthly, a drop of intravenous blood for each patient was taken and saved in FTA card for DNA banking and genotyping. Finally, the demographic, clinical, environmental, administrative and genetic data would be merged for the comprehensive analysis. Discussion. ADACS will give an overview of anti-TB drugs induced ADRs' incidences, risk factors, treatments, prognoses, and clinical, economical and public health impacts for TB patients applying CNTS regimen in China, and provide suggestions for individualized health care and TB control policy. \u00a9 2010 Xia et al; licensee BioMed Central Ltd.",
        "keywords": [
            ""
        ],
        "venue": "BMC Public Health",
        "year": 2010,
        "id": "CJ6HO6j1"
    },
    "K2xf77ng": {
        "authors": [
            {
                "name": "Penghui Shang",
                "org": ""
            },
            {
                "name": "Yinyin Xia",
                "org": ""
            },
            {
                "name": "Feiying Liu",
                "org": ""
            },
            {
                "name": "Xiaomeng Wang",
                "org": ""
            },
            {
                "name": "Yanli Yuan",
                "org": ""
            },
            {
                "name": "Daiyu Hu",
                "org": ""
            },
            {
                "name": "Dehua Tu",
                "org": ""
            },
            {
                "name": "Yixin Chen",
                "org": ""
            },
            {
                "name": "Peiyuan Deng",
                "org": ""
            },
            {
                "name": "Shiming Cheng",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Yu Ma",
                "org": ""
            },
            {
                "name": "Lizhen Zhu",
                "org": ""
            },
            {
                "name": "Weiwei Gao",
                "org": ""
            },
            {
                "name": "Hongyuan Wang",
                "org": ""
            },
            {
                "name": "Dafang Chen",
                "org": ""
            },
            {
                "name": "Li Yang",
                "org": ""
            },
            {
                "name": "Pingping He",
                "org": ""
            },
            {
                "name": "Shanshan Wu",
                "org": ""
            },
            {
                "name": "Shaowen Tang",
                "org": ""
            },
            {
                "name": "Xiaozhen Lv",
                "org": ""
            },
            {
                "name": "Zheng Shu",
                "org": ""
            },
            {
                "name": "Yuan Zhang",
                "org": ""
            },
            {
                "name": "Zhirong Yang",
                "org": ""
            },
            {
                "name": "Yan Chen",
                "org": ""
            },
            {
                "name": "Na Li",
                "org": ""
            },
            {
                "name": "Feng Sun",
                "org": ""
            },
            {
                "name": "Xiaoting Li",
                "org": ""
            },
            {
                "name": "Yingjian He",
                "org": ""
            },
            {
                "name": "Paul Garner",
                "org": ""
            },
            {
                "name": "Siyan Zhan",
                "org": ""
            }
        ],
        "title": "Incidence, clinical features and impact on anti-tuberculosis treatment of anti-tuberculosis drug induced liver injury (ATLI) in China",
        "keywords": [
            ""
        ],
        "venue": "PLoS ONE",
        "year": 2011,
        "id": "K2xf77ng"
    },
    "ab9aizIe": {
        "authors": [
            {
                "name": "Xiao-Xu Han",
                "org": "Key Laboratory of AIDS Immunology of Ministry of Health"
            },
            {
                "name": "Ming-Hui An",
                "org": "Key Laboratory of AIDS Immunology of Ministry of Health"
            },
            {
                "name": "Jun-Jie Xu",
                "org": "Key Laboratory of AIDS Immunology of Ministry of Health"
            },
            {
                "name": "Shi-Ming Cheng",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Yu-Ji Lai",
                "org": ""
            },
            {
                "name": "Fei-Ying Liu",
                "org": ""
            },
            {
                "name": "Hui Zhang",
                "org": "Key Laboratory of AIDS Immunology of Ministry of Health"
            },
            {
                "name": "Bin Zhao",
                "org": "Key Laboratory of AIDS Immunology of Ministry of Health"
            },
            {
                "name": "Zhi-Jun Yang",
                "org": "Key Laboratory of AIDS Immunology of Ministry of Health"
            },
            {
                "name": "Hong Shang",
                "org": "Key Laboratory of AIDS Immunology of Ministry of Health"
            }
        ],
        "title": "The influence of Mycobacterium tuberculosis co-infection and other factors on HIV-1 replication in Guangxi, China",
        "abstract": "Objective: To investigate the influence of Mycobacterium tuberculosis (MTB) co-infection and other factors on the HIV replication level in antiretroviral treatment na\u00efve patients. Methods: Six hundred TB patients and 465 HIV infectors were recruited between April 2010 and September 2010. TB co-infections were diagnosed in HIV infected cases with chest X-ray, checking TB in sputum with anti-acid staining and culture of the sputum, histopatholo diagnosis and clinical diagnosis. HIV infections were screened in TB patients with the 3rd generation ELISA antibody test. Sixty-one antiretroviral treatment na\u00efve HIV/TB co-infectors and 34 HIV infectors with CD4 T cell count below 350 cells/\u03bcl were included in this study. Information about the demography, epidemiology and results of clinical diagnostic tests of HIV and TB was collected through pathography and questionnaires from all participants. HIV viral load were detected with CO-BAS AmpliPrep/COBAS TaqMan ",
        "keywords": [
            "Human immunodeficiency virus type 1",
            "Mycobacterium tuberculosis",
            "Viral load"
        ],
        "venue": "Chinese Journal of Microbiology and Immunology (China)",
        "year": 2011,
        "id": "ab9aizIe"
    },
    "mR6VonKX": {
        "authors": [
            {
                "name": "Jian Xu",
                "org": "Department of Pharmacology"
            },
            {
                "name": "Haixia Jin",
                "org": "Department of Pharmacology"
            },
            {
                "name": "Hui Zhu",
                "org": "Department of Pharmacology"
            },
            {
                "name": "Meiqin Zheng",
                "org": "Department of Pharmacology"
            },
            {
                "name": "Bin Wang",
                "org": "Department of Pharmacology"
            },
            {
                "name": "Chengcheng Liu",
                "org": "Department of Pharmacology"
            },
            {
                "name": "Mingting Chen",
                "org": "National Center for Tuberculosis Control and Prevention"
            },
            {
                "name": "Lin Zhou",
                "org": "National Center for Tuberculosis Control and Prevention"
            },
            {
                "name": "Weijie Zhao",
                "org": "Department of Pharmacology"
            },
            {
                "name": "Lei Fu",
                "org": "Department of Pharmacology"
            },
            {
                "name": "Yu Lu",
                "org": "Department of Pharmacology"
            }
        ],
        "title": "Oral Bioavailability of Rifampicin, Isoniazid, Ethambutol, and Pyrazinamide in a 4-Drug Fixed-Dose Combination Compared With the Separate Formulations in Healthy Chinese Male Volunteers",
        "abstract": "Background: Fixed-dose combination (FDC) formulations for the treatment of tuberculosis are now being recommended by the World Health Organization and used worldwide for reducing the risk of emerging drug resistance. China also plans that theFDCcoverage will be achieved 100% in 2015 in every county in the country. However, the quality of FDCs with respect to variable bioavailability is a major issue. Objectives: This study was conducted in healthy Chinese subjects to compare the bioavailability of rifampicin, isoniazid, ethambutol, and pyrazinamide from a 4-drug FDC formulation versus that of the separate formulations. Methods: The study was designed as randomized, single- dose, 2-treatment, 2-period crossover trial with a washout period of 1 week. Blood samples were collected at 0 (baseline), 10, 20, and 40 minutes and at 1, 1.5, 2, 3, 4, 6, 9, 12, and 24 hours postdose. Plasma concentrations of the 4 drugs were measured by using a rapid chromatography- tandem mass spectrometry method. Pharmacokinetic parameters were calculated by using noncompartmental methods. Bioequivalence was determined if the 90% CIs of the log-transformed test/reference ratios AUC0-24, AUC0-\u221e, and Cmax were within the predetermined range of 80% to 125%. Tolerability was assessed by using clinical parameters and subject reports. Results: A total of 18 male subjects (mean [SD] age, 36.4 [10.6] years) were enrolled and completed the study. In the case of rifampicin, the 90% CIs for the log-transformed ratios of Cmax, AUC0-24, and AUC0-\u221e were 81.8 to 100.9, 89.5 to 100.2, and 87.1 to 98.0, respectively. For ethambutol, these values were 84.7 to 105.7, 93.5 to 105.1, and 92.1 to 105.4. For pyrazinamide, these values were 83.3 to 93.9, 95.8 to 101.4, and 97.0 to 104.1. For isoniazid, the 90% CIs for the log-transformed ratios of AUC0-24, and AUC0\u221e were 83.5 to 94.6 and 83.4 to 94.4. However, the point estimates for Cmax (62.2-86.7) were outside the limit for bioequivalence. No adverse events were observed during the study. Conclusions: The findings from this single-dose study in healthy Chinese male volunteers suggest that the combined formulation was bioequivalent to separate formulations of rifampicin, ethambutol, and pyrazinamide at the same dose levels. However, isoniazid was not bioequivalent based on Cmax values. Both formulations were well tolerated. \u00a9 2013 Elsevier HS Journals, Inc.",
        "keywords": [
            "Bioavailability",
            "Bioequivalence",
            "Combination",
            "Fixeddose",
            "Pharmacokinetics",
            "Tuberculosis"
        ],
        "venue": "Clinical Therapeutics",
        "year": 2013,
        "id": "mR6VonKX"
    },
    "k2Z3kly3": {
        "authors": [
            {
                "name": "Li Bai",
                "org": "State Key Laboratory for Infectious Diseases Prevention and Control"
            },
            {
                "name": "Cirendunzhu",
                "org": "Tibet Center for Disease Control and Prevention"
            },
            {
                "name": "Pengcuociren",
                "org": "Tibet Center for Disease Control and Prevention"
            },
            {
                "name": "Dawa",
                "org": "Tibet Center for Disease Control and Prevention"
            },
            {
                "name": "Alistair Woodward",
                "org": "School of Population Health"
            },
            {
                "name": "Xiaobo Liu",
                "org": "State Key Laboratory for Infectious Diseases Prevention and Control"
            },
            {
                "name": "Baimaciwang",
                "org": "Tibet Center for Disease Control and Prevention"
            },
            {
                "name": "Dazhen",
                "org": "Tibet Center for Disease Control and Prevention"
            },
            {
                "name": "Shaowei Sang",
                "org": "State Key Laboratory for Infectious Diseases Prevention and Control"
            },
            {
                "name": "Fangjun Wan",
                "org": "State Key Laboratory for Infectious Diseases Prevention and Control"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory for Infectious Diseases Prevention and Control"
            },
            {
                "name": "Junfang Xu",
                "org": "Center for Health Management and Policy"
            },
            {
                "name": "Xiaolu Li",
                "org": "Center for Health Management and Policy"
            },
            {
                "name": "Haixia Wu",
                "org": "State Key Laboratory for Infectious Diseases Prevention and Control"
            },
            {
                "name": "Baorong Yu",
                "org": "Center for Health Management and Policy"
            },
            {
                "name": "Xiraoruodeng",
                "org": "Tibet Center for Disease Control and Prevention"
            },
            {
                "name": "Qiyong Liu",
                "org": "Climate Change and Health Center"
            }
        ],
        "title": "Rapid warming in Tibet, China: Public perception, response and coping resources in urban Lhasa",
        "abstract": "Background: Tibet, average altitude more than 4,000 meters, is warming faster than anywhere else in China. The increase in temperatures may aggravate existing health problems and lead to the emergence of new risks. However, there are no actions being taken at present to protect population health due to limited understanding about the range and magnitude of health effects of climate change. Methods. The study was a cross-sectional survey of 619 respondents from urban Lhasa, Tibet in August 2012 with the aim to investigate public perceptions of risk, heat experiences, and coping resources. Results: Respondents are aware of the warming that has occurred in Lhasa in recent years. Over 78% reported that rising temperature is either a \"very\" or \"somewhat\" serious threat to their own health, and nearly 40% reported they had experienced heat-related symptoms. Sex, age, education and income influenced perceived risks, health status, and heat experience. The vast majority of respondents reported that they had altered their behaviour on hot summer days. Bakuo, a sub-district at the city center, is considered especially vulnerable to heat because of sparse vegetation, high population density, poor dwelling conditions and a high proportion of low-income population. However, neighborhood social ties were stronger in Bakuo than other study locations. Conclusions: The study suggests that actions are needed now to minimize downside effects of rapid warming in Tibet, because of increasing human exposure to high temperatures and uneven distribution of the resources needed to cope. \u00a9 2013 Bai et al.; licensee BioMed Central Ltd.",
        "keywords": [
            "Climate change",
            "Global warming",
            "Human health",
            "Perceptions",
            "Tibet",
            "Vulnerability"
        ],
        "venue": "Environmental Health: A Global Access Science Source",
        "year": 2013,
        "id": "k2Z3kly3"
    },
    "Lpv8ZKXR": {
        "authors": [
            {
                "name": "Wen Shu",
                "org": "Department of Public Health"
            },
            {
                "name": "Wei Chen",
                "org": "National Center for Tuberculosis Control and Prevention"
            },
            {
                "name": "Shiyu Zhu",
                "org": "Department of Epidemiology and Biostatistics"
            },
            {
                "name": "Yongchun Hou",
                "org": "Department of Epidemiology and Biostatistics"
            },
            {
                "name": "Jian Mei",
                "org": "Shanghai Municipal Center for Disease Control and Prevention"
            },
            {
                "name": "Liqiong Bai",
                "org": "TB Institute for Tuberculosis Control and Prevention of Hunan Province"
            },
            {
                "name": "Weiguo Xu",
                "org": "Jiangsu Provincial Center for Disease Control and Prevention"
            },
            {
                "name": "Lin Zhou",
                "org": "TB Institute for Tuberculosis Control and Prevention of Guangdong Province"
            },
            {
                "name": "Shaofa Nie",
                "org": "Department of Epidemiology and Biostatistics"
            },
            {
                "name": "Shiming Cheng",
                "org": "National Center for Tuberculosis Control and Prevention"
            },
            {
                "name": "Yihua Xu",
                "org": "Department of Epidemiology and Biostatistics"
            }
        ],
        "title": "Factors causing delay of access to tuberculosis diagnosis among new, active tuberculosis patients: A prospective cohort study",
        "abstract": "Few studies have examined, in a prospective cohort study, factors causing delay of access to tuberculosis (TB) diagnosis among new, active TB patients. A prospective cohort study (2009-2011) was carried out among 408 889 Chinese. Data on known/potential influencing factors were obtained from baseline questionnaires. We used stepwise logistic regression models to analyze the association between several known/potential influencing factors and diagnosis delay, assessed the current situation, and explored determinants of diagnosis delay. During follow-up and final visits, 202 new, active TB patients were found. Median patient delay was 5.4 (quartile 2.7-26) weeks, health system delay was 0 (quartile 0-1.6) weeks, and diagnosis delay was 9.9 (quartile 3.1-28.1) weeks. The influencing factors on patient delay were age and duration of symptoms. Smoking and sputum smear status were influencing factors for health system delay, and duration of symptoms was one of the factors for diagnosis delay. These findings provide information on the current situation of diagnosis delay and evidence for specific strategy development for TB control in China. \u00a9 2013 APJPH.",
        "keywords": [
            "diagnosis delay",
            "influencing factors",
            "pulmonary tuberculosis"
        ],
        "venue": "Asia-Pacific Journal of Public Health",
        "year": 2014,
        "id": "Lpv8ZKXR"
    },
    "2uxKmCDN": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "School of Public Health"
            },
            {
                "name": "Zheng Xin",
                "org": "Jinan Municipal Center for Disease Control and Prevention"
            },
            {
                "name": "Li Bai",
                "org": "State Key Laboratory for Infectious Disease Prevention and Control"
            },
            {
                "name": "Fangjun Wan",
                "org": "State Key Laboratory for Infectious Disease Prevention and Control"
            },
            {
                "name": "Yongming Wang",
                "org": "Jinan Municipal Center for Disease Control and Prevention"
            },
            {
                "name": "Shaowei Sang",
                "org": "State Key Laboratory for Infectious Disease Prevention and Control"
            },
            {
                "name": "Shouqin Liu",
                "org": "Jinan Municipal Center for Disease Control and Prevention"
            },
            {
                "name": "Ji Zhang",
                "org": "Jinan Municipal Center for Disease Control and Prevention"
            },
            {
                "name": "Qiyong Liu",
                "org": "Shandong University Climate Change and Health Center"
            }
        ],
        "title": "Perceptions of heat risk to health:A qualitative study of professional bus drivers and their managers in Jinan, China",
        "keywords": [
            "Heat",
            "Occupational driver",
            "Public health",
            "Risk perception"
        ],
        "venue": "International Journal of Environmental Research and Public Health",
        "year": 2014,
        "id": "2uxKmCDN"
    },
    "SVLNBmto": {
        "authors": [
            {
                "name": "Junjie Xu",
                "org": "Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases"
            },
            {
                "name": "Weiming Tang",
                "org": "Department of Epidemiology, Fielding School of Public Health, University of California"
            },
            {
                "name": "Shiming Cheng",
                "org": "Center for Tuberculosis Control and Prevention, National Center for Disease Control and Prevention (CDC)"
            },
            {
                "name": "Tanmay Mahapatra",
                "org": "Department of Epidemiology, Fielding School of Public Health, University of California"
            },
            {
                "name": "Lin Zhou",
                "org": "Center for Tuberculosis Control and Prevention, National Center for Disease Control and Prevention (CDC)"
            },
            {
                "name": "Yuji Lai",
                "org": "Center for Tuberculosis Control and Prevention, National Center for Disease Control and Prevention (CDC)"
            },
            {
                "name": "Yongjun Jiang",
                "org": "Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases"
            },
            {
                "name": "Feiying Liu",
                "org": "Center for Tuberculosis Control and Prevention, Guangxi Autonomous Region CDC"
            },
            {
                "name": "Xinan Zhen",
                "org": "Center for Tuberculosis Control and Prevention, HenanProvincialCDC"
            },
            {
                "name": "Jinge He",
                "org": "Center for Tuberculosis Control and Prevention, SichuanProvincialCDC"
            },
            {
                "name": "Jing Zhang",
                "org": "Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases"
            },
            {
                "name": "Jinxin Lu",
                "org": "Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases"
            },
            {
                "name": "Sanchita Mahapatra",
                "org": "Department of Epidemiology, Fielding School of Public Health, University of California"
            },
            {
                "name": "Hong Shang",
                "org": "Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases"
            }
        ],
        "title": "Prevalence and predictors of HIV among Chinese tuberculosis patients by provider-initiated HIV testing and counselling (PITC): A multisite study in south central of China",
        "abstract": "Background: Tuberculosis (TB) and HIV are two worldwide public health concerns. Co-infection of these two diseases has been considered to be a major obstacle for the global efforts in reaching the goals for the prevention of HIV and TB. Method: A comprehensive cross-sectional study was conducted to recruit TB patients in three provinces (Guangxi, Henan and Sichuan) of China between April 1 and September 30, 2010. Results: A total of 1,032 consenting TB patients attended this survey during the study period. Among the participants, 3.30% were HIV positive; about one quarter had opportunistic infections. Nearly half of the participants were 50 years or older, the majority were male and about one third were from minority ethnic groups. After adjusting for site, gender and areas of residence (using the partial/selective Model 1), former commercial plasma donors (adjusted OR [aOR] = 33.71) and injecting drug users(aOR = 15.86) were found to have significantly higher risk of being HIV-positivity. In addition, having extramarital sexual relationship (aOR = 307.16), being engaged in commercial sex (aOR = 252.37), suffering from opportunistic infections in the past six months (aOR = 2.79), losing 10% or more of the body weight in the past six months (aOR = 5.90) and having abnormal chest X-ray findings (aOR = 20.40) were all significantly associated with HIV seropositivity (each p<0.05). Conclusions: HIV prevalence among TB patients was high in the study areas of China. To control the dual epidemic, intervention strategies targeting socio-demographic and behavioral factors associated with higher risk of TB-HIV co-infection are urgently called for. \u00a9 2014 Xu et al.",
        "keywords": [
            ""
        ],
        "venue": "PLoS ONE",
        "year": 2014,
        "id": "SVLNBmto"
    },
    "8GI9rcUj": {
        "authors": [
            {
                "name": "Xiaobo Liu",
                "org": ""
            },
            {
                "name": "Fangjun Wan",
                "org": ""
            },
            {
                "name": "Cirendunzhu",
                "org": ""
            },
            {
                "name": "Cirenwangla",
                "org": ""
            },
            {
                "name": "Li Bai",
                "org": ""
            },
            {
                "name": "Pengcuociren",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Baimaciwang",
                "org": ""
            },
            {
                "name": "Yuhong Guo",
                "org": ""
            },
            {
                "name": "Dazhen",
                "org": ""
            },
            {
                "name": "Junfang Xu",
                "org": ""
            },
            {
                "name": "Shaowei Sang",
                "org": ""
            },
            {
                "name": "Xiaolu Li",
                "org": ""
            },
            {
                "name": "Shaohua Gu",
                "org": ""
            },
            {
                "name": "Haixia Wu",
                "org": ""
            },
            {
                "name": "Jun Wang",
                "org": ""
            },
            {
                "name": "Dawa",
                "org": ""
            },
            {
                "name": "Xiraoruodeng",
                "org": ""
            },
            {
                "name": "Qiyong Liu",
                "org": ""
            }
        ],
        "title": "Community knowledge and experience of mosquitoes and personal prevention and control practices in Lhasa, Tibet",
        "abstract": "Since 2009, great public attention has been paid in Lhasa City (Tibet, China) to mosquito bites and accompanying inflammatory complications. However, the potential contribution of knowledge levels, experiences, disease control and preventive practices (KEP) towards mosquitoes has not received much attention. To investigate community KEP concerning mosquitoes in Lhasa, a cross-sectional survey was undertaken in four sub-districts of urban Lhasa in 2012. Questionnaires were designed to collect information regarding socio-demographics and KEP concerning the harmful effects of mosquitoes on participants. The scoring for KEP was developed after consultation of literature. A total of 591 eligible questionnaires were examined. The majority of respondents were female (61.8%) with a mean age of 46 years. Nearly all of the respondents were of Tibetan nationality (97.4%) and living in registered native households (92.7%), who have less than primary school education. The averages of overall score, knowledge score, experience score, and practice score were 9.23, 4.53, 1.80, 2.90, respectively. The registered household with the highest overall score, knowledge score and practice score was non-native. Female subjects with monthly incomes between 1000 and 3000 RMB had higher experience scores. The correlation analysis revealed that significant positive linear correlations existed between knowledge and experience, knowledge and practices, and experience and practices towards mosquitoes. Past experiences with mosquitoes can result in a better knowledge of effective mosquito control practices in the present and the future. Though the average of overall scores related to mosquitoes is high among the participants in Lhasa, however, the knowledge about the ecological habits of mosquitoes should be strengthened. The findings in this study may help to develop strategies and measures of mosquito and mosquito-borne diseases in the future, not only in Lhasa, but also in similar altitude, latitude and longitude regions worldwide.",
        "keywords": [
            "Experience",
            "Knowledge",
            "Mosquito",
            "Prevention and control practice",
            "Public health",
            "Tibet"
        ],
        "venue": "International Journal of Environmental Research and Public Health",
        "year": 2014,
        "id": "8GI9rcUj"
    },
    "vourc6EL": {
        "authors": [
            {
                "name": "Yu Ji Lai",
                "org": "Center for Tuberculosis Control and Prevention, Chinese Center for Disease Control and Prevention"
            },
            {
                "name": "Er Yong Liu",
                "org": "Center for Tuberculosis Control and Prevention, Chinese Center for Disease Control and Prevention"
            },
            {
                "name": "Li Ming Wang",
                "org": "Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention"
            },
            {
                "name": "Jamie P Morano",
                "org": "Division of Infectious Diseases and International Medicine, Morsani College of Medicine, University of South Florida"
            },
            {
                "name": "Ning Wang",
                "org": "Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention"
            },
            {
                "name": "Kaveh Khoshnood",
                "org": "Yale University School of Public Health"
            },
            {
                "name": "Lin Zhou",
                "org": "Center for Tuberculosis Control and Prevention, Chinese Center for Disease Control and Prevention"
            },
            {
                "name": "Shi Ming Cheng",
                "org": "Center for Tuberculosis Control and Prevention, Chinese Center for Disease Control and Prevention"
            }
        ],
        "title": "Human Immunodeficiency Virus Infection-Associated Mortality during Pulmonary Tuberculosis Treatment in Six Provinces of China",
        "abstract": "Objective To investigate the risk factors attributable to tuberculosis-related deaths in areas with human immunodeficiency virus (HIV) infection epidemics. Methods A prospective cohort study of newly registered patients in tuberculosis (TB) dispensaries in six representative Chinese provinces was conducted from September 1, 2009 to August 31, 2011. Risk factors for TB-associated death were identified through logistic regression analysis. Results Of 19,103 newly registered pulmonary TB patients, 925 (4.8%) were found to be HIV-positive. Miliary TB and acid-fast bacillus smear-negative TB were more common among these patients. Out of a total of 322 (1.7%) deaths that occurred during TB treatment, 85 (26%) of the patients were co-infected with HIV. Multivariate analysis revealed that HIV infection was the strongest predictor of death [adjusted odds ratio (aOR) 7.86]. Other significant mortality risk factors included presentation with miliary TB (aOR 4.10; 95% confidence interval: 2.14-7.88), \u226535 years of age (aOR 3.04), non-Han ethnicity (aOR 1.67), and farming as an occupation (aOR 1.59). For patients with TB/HIV co-infection, miliary TB was the strongest risk factor for death (aOR 5.48). A low CD4 count (\u2264 200 cells/\u03bcL) (aOR 3.27) at the time of TB treatment initiation and a lack of antiretroviral therapy (ART) administration (aOR 3.78) were also correlated with an increased risk of death. Conclusion Infection with HIV was independently associated with increased mortality during TB treatment. Offering HIV testing at the time of diagnosis with TB, early TB diagnosis among HIV/acquired immunodeficiency syndrome patients, and the timely provision of ART were identified as the key approaches that could reduce the number of HIV-associated TB deaths.",
        "keywords": [
            "Acquired immunodeficiency syndrome",
            "Human immunodeficiency virus",
            "Mortality",
            "Tuberculosis"
        ],
        "venue": "Biomedical and Environmental Sciences",
        "year": 2015,
        "id": "vourc6EL"
    },
    "54v0nKBc": {
        "authors": [
            {
                "name": "Jizhao Liang",
                "org": "School of Mechanical and Automotive Engineering"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Mechanical and Automotive Engineering"
            },
            {
                "name": "Liu He",
                "org": "School of Mechanical and Automotive Engineering"
            }
        ],
        "title": "Melt flow properties of PDLLA/nano-CaCO3 composites",
        "abstract": "Poly(DL-lactic acid)/nano-calcium carbonate(PDLLA/nano-CaCO",
        "keywords": [
            "Composite",
            "Melt density",
            "Melt volume flow rate",
            "Nano-CaCO3",
            "Poly(DL-lactic acid)"
        ],
        "venue": "Hecheng Shuzhi Ji Suliao/China Synthetic Resin and Plastics",
        "year": 2011,
        "id": "54v0nKBc"
    },
    "HxBvXkBA": {
        "authors": [
            {
                "name": "Ji-Zhao Liang",
                "org": "School of Mechanical and Automotive Engineering"
            },
            {
                "name": "Chak-Yin Tang",
                "org": "Department of Industrial and Systems Engineering"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Mechanical and Automotive Engineering"
            },
            {
                "name": "Liu He",
                "org": "School of Mechanical and Automotive Engineering"
            },
            {
                "name": "Chi-Pong Tsui",
                "org": "Department of Industrial and Systems Engineering"
            }
        ],
        "title": "Melt density and flow property of PDLLA/nano-CaCO3 bio-composites",
        "abstract": "The nanometer calcium carbonate (nano-CaCO",
        "keywords": [
            "A. Polymer-matrix composites",
            "B. Rheological properties",
            "E. Extrusion",
            "E. Resin flow"
        ],
        "venue": "Composites Part B: Engineering",
        "year": 2011,
        "id": "HxBvXkBA"
    },
    "Mcs2wbzZ": {
        "authors": [
            {
                "name": "Ji-Zhao Liang",
                "org": "School of Mechanical and Automotive Engineering"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Mechanical and Automotive Engineering"
            },
            {
                "name": "Chak-Yin Tang",
                "org": "Department of Industrial and Systems Engineering"
            },
            {
                "name": "Chi-Pong Tsui",
                "org": "Department of Industrial and Systems Engineering"
            },
            {
                "name": "Feng-Jiao Li",
                "org": "School of Mechanical and Automotive Engineering"
            }
        ],
        "title": "Melt flow behavior in capillary extrusion of nanometer calcium carbonate filled PCL bio-composites",
        "abstract": "Nanosized calcium carbonate (nano-CaCO ",
        "keywords": [
            "Bio-composites",
            "Flow property",
            "Melt extrusion",
            "Nano-CaCO 3",
            "PCL"
        ],
        "venue": "Polymer Testing",
        "year": 2012,
        "id": "Mcs2wbzZ"
    },
    "lcW0Hal5": {
        "authors": [
            {
                "name": "Ji-Zhao Liang",
                "org": "Research Division of Green Function Materials and Equipment"
            },
            {
                "name": "Chak-Yin Tang",
                "org": "Department of Industrial and Systems Engineering"
            },
            {
                "name": "Lin Zhou",
                "org": "Research Division of Green Function Materials and Equipment"
            },
            {
                "name": "Chi-Pong Tsui",
                "org": "Department of Industrial and Systems Engineering"
            },
            {
                "name": "Feng-Jiao Li",
                "org": "Research Division of Green Function Materials and Equipment"
            }
        ],
        "title": "Melt flow behavior in capillary extrusion of nanosized calcium carbonate-filled poly(L -lactic acid) biocomposites",
        "abstract": "Nanosized calcium carbonate (nano-CaCO ",
        "keywords": [
            ""
        ],
        "venue": "Polymer Engineering and Science",
        "year": 2012,
        "id": "lcW0Hal5"
    },
    "BQdzNOOB": {
        "authors": [
            {
                "name": "Fengjiao Li",
                "org": "School of Mechanical and Automotive Engineering"
            },
            {
                "name": "Jia Yang",
                "org": "School of Mechanical and Automotive Engineering"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Mechanical and Automotive Engineering"
            },
            {
                "name": "Yukun Zhang",
                "org": "School of Mechanical and Automotive Engineering"
            },
            {
                "name": "Jizhao Liang",
                "org": "School of Mechanical and Automotive Engineering"
            }
        ],
        "title": "Flow properties and extrudate swell during extrusion of polycaprolactone melt",
        "abstract": "The influences of temperature, apparent shear rate(\u03b3",
        "keywords": [
            "Extrudate swell",
            "Flow properties",
            "Melt extrusion",
            "Polycaprolactone"
        ],
        "venue": "Hecheng Shuzhi Ji Suliao/China Synthetic Resin and Plastics",
        "year": 2012,
        "id": "BQdzNOOB"
    },
    "JZRtTKqR": {
        "authors": [
            {
                "name": "Ji-Zhao Liang",
                "org": "Research Division of Green Function Materials and Equipment"
            },
            {
                "name": "Lin Zhou",
                "org": "Research Division of Green Function Materials and Equipment"
            },
            {
                "name": "Chak-Yin Tang",
                "org": "Department of Industrial and Systems Engineering"
            },
            {
                "name": "Chi-Pong Tsui",
                "org": "Department of Industrial and Systems Engineering"
            }
        ],
        "title": "Crystalline properties of poly(L-lactic acid) composites filled with nanometer calcium carbonate",
        "abstract": "The poly(L-lactic acid) (PLLA) filled with nanometer calcium carbonate (nano-CaCO",
        "keywords": [
            "A. Polymer-matrix composites",
            "B. Physical properties",
            "D. Thermal analysis"
        ],
        "venue": "Composites Part B: Engineering",
        "year": 2013,
        "id": "JZRtTKqR"
    },
    "R9L38bU6": {
        "authors": [
            {
                "name": "Ji-Zhao Liang",
                "org": "Research Division of Green Function Materials and Equipment"
            },
            {
                "name": "Lin Zhou",
                "org": "Research Division of Green Function Materials and Equipment"
            },
            {
                "name": "Chak-Yin Tang",
                "org": "Department of Industrial and Systems Engineering"
            },
            {
                "name": "Chi-Pong Tsui",
                "org": "Department of Industrial and Systems Engineering"
            }
        ],
        "title": "Crystallization properties of polycaprolactone composites filled with nanometer calcium carbonate",
        "abstract": "Polycaprolactone (PCL) composites filled with nanometer calcium carbonate (nano-CaCO",
        "keywords": [
            "composites",
            "crystallization",
            "differential scanning calorimetry (DSC)",
            "nanostructured polymers"
        ],
        "venue": "Journal of Applied Polymer Science",
        "year": 2013,
        "id": "R9L38bU6"
    },
    "10UjUElw": {
        "authors": [
            {
                "name": "Ji-Zhao Liang",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Chak-Yin Tang",
                "org": ""
            },
            {
                "name": "Chi-Pong Tsui",
                "org": ""
            }
        ],
        "title": "Melt Flow Behavior in Capillary Extrusion of Nanosized Calcium Carbonate Filled PLLA/PCL Bio-Composites",
        "abstract": "Nanosized calcium carbonate (nano-CaCO",
        "keywords": [
            "Bio-composites",
            "Flow property",
            "Melt extrusion",
            "Nano-CaCO3",
            "PCL",
            "PLLA"
        ],
        "venue": "Journal of Polymers and the Environment",
        "year": 2013,
        "id": "10UjUElw"
    },
    "NvP6Upek": {
        "authors": [
            {
                "name": "Jiake Xu",
                "org": ""
            },
            {
                "name": "Qian Liu",
                "org": ""
            },
            {
                "name": "Huafei Wu",
                "org": ""
            },
            {
                "name": "Shek Man Chim",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Jinmin Zhao",
                "org": ""
            },
            {
                "name": "Haotian Feng",
                "org": ""
            },
            {
                "name": "Qingli Wei",
                "org": ""
            },
            {
                "name": "Qing Wang",
                "org": ""
            },
            {
                "name": "Ming H. Zheng",
                "org": ""
            },
            {
                "name": "Ren Xiang Tan",
                "org": ""
            },
            {
                "name": "Qiong Gu",
                "org": ""
            },
            {
                "name": "Jun Xu",
                "org": ""
            },
            {
                "name": "Nathan Pavlos",
                "org": ""
            },
            {
                "name": "Jennifer Tickner",
                "org": ""
            }
        ],
        "title": "SC-514, a selective inhibitor of IKK\u03b2 attenuates RANKL-induced osteoclastogenesis and NF-\u03baB activation",
        "keywords": [
            "Bone marrow cells",
            "NF-\u03baB",
            "Osteoclastogenesis",
            "RANKL",
            "SC-514"
        ],
        "venue": "Biochemical Pharmacology",
        "year": 2013,
        "id": "NvP6Upek"
    },
    "DI58i4Yo": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "An-Zhong Peng",
                "org": ""
            },
            {
                "name": "Shen-Gui Ju",
                "org": ""
            }
        ],
        "title": "Adsorption of thiophenic sulfur in transition metal ion modified Na-13X zeolites",
        "abstract": "Cu",
        "keywords": [
            "Desulfurization",
            "Thiophenic sulfur",
            "Transition metal ions",
            "\u03c0-complexation"
        ],
        "venue": "Gao Xiao Hua Xue Gong Cheng Xue Bao/Journal of Chemical Engineering of Chinese Universities",
        "year": 2015,
        "id": "DI58i4Yo"
    },
    "mhfbYpOm": {
        "authors": [
            {
                "name": "Jianbin Huang",
                "org": "Orthopaedic Department, Memorial Hospital of Sun Yat-sen University"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Pathology and Laboratory Medicine, The University of Western Australia"
            },
            {
                "name": "Huafei Wu",
                "org": "Research Centre for Regenerative Medicine, Department of Orthopaedic Surgery, The First Affiliated Hospital of Guangxi Medical University"
            },
            {
                "name": "Nathan Pavlos",
                "org": "Centre for Orthopaedic Research, School of Surgery, The University of Western Australia"
            },
            {
                "name": "Shek Man Chim",
                "org": "School of Pathology and Laboratory Medicine, The University of Western Australia"
            },
            {
                "name": "Qian Liu",
                "org": "Research Centre for Regenerative Medicine, Department of Orthopaedic Surgery, The First Affiliated Hospital of Guangxi Medical University"
            },
            {
                "name": "Jinmin Zhao",
                "org": "Research Centre for Regenerative Medicine, Department of Orthopaedic Surgery, The First Affiliated Hospital of Guangxi Medical University"
            },
            {
                "name": "Wei Xue",
                "org": "Key Laboratory of Biomaterials of Guangdong Higher Education Institutes, Department of Biomedical Engineering, Jinan University"
            },
            {
                "name": "Ren Xiang Tan",
                "org": "Institute of Functional Biomolecules, Medical School, Nanjing University"
            },
            {
                "name": "Jiming Ye",
                "org": "Health Innovations Research Institute and School of Health Sciences, RMIT University"
            },
            {
                "name": "Jun Xu",
                "org": "Research Center for Drug Discovery (RCDD), School of Pharmaceutical Sciences, Sun Yat-Sen University"
            },
            {
                "name": "Estabelle S. Ang",
                "org": "School of Dentistry, University of Western Australia"
            },
            {
                "name": "Haotian Feng",
                "org": "Program of Nutrition and Bone and oJoint Health, Nestl\u00e9 R and D (China) Ltd. Building 5"
            },
            {
                "name": "Jennifer Tickner",
                "org": "School of Pathology and Laboratory Medicine, The University of Western Australia"
            },
            {
                "name": "Jiake Xu",
                "org": "School of Pathology and Laboratory Medicine, The University of Western Australia"
            },
            {
                "name": "Yue Ding",
                "org": "Orthopaedic Department, Memorial Hospital of Sun Yat-sen University"
            }
        ],
        "title": "Triptolide inhibits osteoclast formation, bone resorption, RANKL-mediated NF-[U+049B]B activation and titanium particle-induced osteolysis in a mouse model",
        "keywords": [
            "NF-\u03baB",
            "Osteoclastogenesis",
            "Osteolysis",
            "RANKL",
            "Titanium particle",
            "Triptolide"
        ],
        "venue": "Molecular and Cellular Endocrinology",
        "year": 2015,
        "id": "mhfbYpOm"
    },
    "0O23xF3S": {
        "authors": [
            {
                "name": "Shengnan Qin",
                "org": "Guangzhou Institute of Traumatic Surgery"
            },
            {
                "name": "Estabelle Ang",
                "org": "School of Dentistry"
            },
            {
                "name": "Libing Dai",
                "org": "Guangzhou Institute of Traumatic Surgery"
            },
            {
                "name": "Xiaohong Yang",
                "org": "Guangzhou Institute of Traumatic Surgery"
            },
            {
                "name": "Dongping Ye",
                "org": "School of Pathology and Laboratory Medicine"
            },
            {
                "name": "Honghui Chen",
                "org": "Guangzhou Institute of Traumatic Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Pathology and Laboratory Medicine"
            },
            {
                "name": "Mingli Yang",
                "org": "School of Pathology and Laboratory Medicine"
            },
            {
                "name": "Dian Teguh",
                "org": "School of Pathology and Laboratory Medicine"
            },
            {
                "name": "Renxiang Tan",
                "org": "Institute of Functional Biomolecules"
            },
            {
                "name": "Jun Xu",
                "org": "Research Center for Drug Discovery (RCDD)"
            },
            {
                "name": "Jennifer Tickner",
                "org": "School of Pathology and Laboratory Medicine"
            },
            {
                "name": "Nathan J. Pavlos",
                "org": "Centre for Orthopaedic Research"
            },
            {
                "name": "Jiake Xu",
                "org": "School of Pathology and Laboratory Medicine"
            }
        ],
        "title": "Natural germacrane sesquiterpenes inhibit osteoclast formation, bone resorption, RANKL-induced NF-\u03baB activation, and I\u03baB\u03b1 degradation",
        "abstract": "Osteolytic bone diseases are commonly presented with enhanced osteoclast formation and bone resorption. Sesquiterpene lactone natural compounds have been found to possess anti-inflammatory and immune-modulation effects. Here, we identified three germacrane sesquiterpenes using computer-based virtual screening for the structural similarity with sesquiterpene lactone, parthenolide. We showed that natural germacrane sesquiterpene compounds A, B, and C inhibit osteoclast formation and bone resorption in a dose-dependent manner, with relative potency compound A > compound C > compound B based on their equimolar concentrations. Mechanistic studies by Luciferase reporter gene assay and Western blot analysis showed that germacrane sesquiterpene compound A inhibits RANKL-induced activation of NF-\u03baB and I\u03baB\u03b1 degradation. This study reveals that natural germacrane sesquiterpene compounds are inhibitors for osteoclast formation and bone resorption, and provides evidence that naturally-occurring compounds might be beneficial as alternative medicine for the prevention and treatment of osteolysis.",
        "keywords": [
            "Bone resorption",
            "Germacrane sesquiterpenes",
            "I\u03baB\u03b1",
            "NF-\u03baB",
            "Osteoclastogenesis",
            "RANKL"
        ],
        "venue": "International Journal of Molecular Sciences",
        "year": 2015,
        "id": "0O23xF3S"
    },
    "6RVP4h0M": {
        "authors": [
            {
                "name": "Tao Wang",
                "org": "Guangxi Key Laboratory of Regenerative Medicine"
            },
            {
                "name": "Qian Liu",
                "org": "Department of Orthopedics Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Pathology and Laboratory Medicine"
            },
            {
                "name": "Jin Bo Yuan",
                "org": "School of Pathology and Laboratory Medicine"
            },
            {
                "name": "Xixi Lin",
                "org": "Department of Orthopedics Surgery"
            },
            {
                "name": "Rong Zeng",
                "org": "Department of Orthopedics Surgery"
            },
            {
                "name": "Xiaonan Liang",
                "org": "Department of Orthopedics Surgery"
            },
            {
                "name": "Jinmin Zhao",
                "org": "Guangxi Key Laboratory of Regenerative Medicine"
            },
            {
                "name": "Jiake Xu",
                "org": "School of Pathology and Laboratory Medicine"
            }
        ],
        "title": "Andrographolide inhibits ovariectomy-induced bone loss via the suppression of RANKL signaling pathways",
        "keywords": [
            "Andrographolide",
            "Bone loss",
            "Osteoclastogenesis",
            "OVX",
            "RANKL"
        ],
        "venue": "International Journal of Molecular Sciences",
        "year": 2015,
        "id": "6RVP4h0M"
    },
    "Ktzu0oS2": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "School of Pathology and Laboratory Medicine"
            },
            {
                "name": "Fangming Song",
                "org": "Pharmaceutical college"
            },
            {
                "name": "Qian Liu",
                "org": "Department of Orthopaedic Surgery"
            },
            {
                "name": "Mingli Yang",
                "org": "School of Pathology and Laboratory Medicine"
            },
            {
                "name": "Jinmin Zhao",
                "org": "Department of Orthopaedic Surgery"
            },
            {
                "name": "Renxiang Tan",
                "org": "Institute of Functional Biomolecules"
            },
            {
                "name": "Jun Xu",
                "org": "Research Center for Drug Discovery (RCDD)"
            },
            {
                "name": "Ge Zhang",
                "org": "Institute for Advancing Translational Medicine in Bone and Joint Diseases"
            },
            {
                "name": "Julian M. W. Quinn",
                "org": "The Garvan Institute of Medical Research"
            },
            {
                "name": "Jennifer Tickner",
                "org": "School of Pathology and Laboratory Medicine"
            },
            {
                "name": "Jiake Xu",
                "org": "Research Centre for Regenerative Medicine"
            }
        ],
        "title": "Berberine sulfate attenuates osteoclast differentiation through RANKL induced NF-\u03baB and NFAT pathways",
        "keywords": [
            "Berberine sulfate",
            "NF-\u03baB and NFAT pathway",
            "Osteoclast",
            "RANKL"
        ],
        "venue": "International Journal of Molecular Sciences",
        "year": 2015,
        "id": "Ktzu0oS2"
    },
    "3WF2Aqzt": {
        "authors": [
            {
                "name": "Guoju Yin",
                "org": "Hu'nan Key Laboratory of Ultra-precision Machining Technology"
            },
            {
                "name": "Shengyi Li",
                "org": "Hu'nan Key Laboratory of Ultra-precision Machining Technology"
            },
            {
                "name": "Xuhui Xie",
                "org": "Hu'nan Key Laboratory of Ultra-precision Machining Technology"
            },
            {
                "name": "Lin Zhou",
                "org": "Hu'nan Key Laboratory of Ultra-precision Machining Technology"
            }
        ],
        "title": "Ultra-precision process of CaF<inf>2</inf> single crystal",
        "abstract": "This paper proposes a new chemical mechanical polishing (CMP) process method for CaF<inf>2</inf> single crystal to get ultraprecision surface. The CMP processes are improving polishing pad and using alkaline SiO<inf>2</inf> polishing slurry with PH=8, PH=11 two phases to polish, respectively, and the roughness can be 0.181nm Rq (10\u03bcm\u00d710\u03bcm). The CMP process can't get high surface figure, so we use ion beam figuring (IBF) technology to obtain high surface figure. However, IBF is difficult to improve the CaF<inf>2</inf> surface roughness. We optimize IBF process to improve surface figure and keep good surface roughness too. Different IBF incident ion energy from 400ev to 800ev does not affect on the surface roughness obviously but the depth of material removal is reverse. CaF<inf>2</inf> single crystal can get high precision surface figure (RMS=2.251nm) and still keep ultra-smooth surface (Rq=0.207nm) by IBF when removal depth is less than 200nm. The researches above provide important information for CaF<inf>2</inf> single crystal to realize ultra-precision manufacture.",
        "keywords": [
            "CaF<inf>2</inf> single crystal",
            "chemical mechanical polishing",
            "Deposition layer",
            "Ion beam figuring",
            "Ultra-precision"
        ],
        "venue": "Proceedings of SPIE - The International Society for Optical Engineering",
        "year": 2014,
        "id": "3WF2Aqzt"
    },
    "DYummFTw": {
        "authors": [
            {
                "name": "Wenlin Liao",
                "org": "Hu'nan Key Laboratory of Ultra-Precision Machining Technology"
            },
            {
                "name": "Yifan Dai",
                "org": "Hu'nan Key Laboratory of Ultra-Precision Machining Technology"
            },
            {
                "name": "Xuhui Xie",
                "org": "Hu'nan Key Laboratory of Ultra-Precision Machining Technology"
            },
            {
                "name": "Lin Zhou",
                "org": "Hu'nan Key Laboratory of Ultra-Precision Machining Technology"
            }
        ],
        "title": "Mathematical modeling and application of removal functions during deterministic ion beam figuring of optical surfaces. Part 1: Mathematical modeling",
        "abstract": "Ion beam figuring (IBF) is established for the final precision figuring of high-performance optical components, where the figuring accuracy is guaranteed by the stability of the removal function and the solution accuracy of the dwell time. In this deterministic method, the figuring process can be represented by a two-dimensional (2D) convolution operation of a constant removal function and the dwell time. However, we have found that the current 2D convolution operation cannot factually describe the IBF process of curved surfaces, which neglects the influences of the projection distortion and the work-piece geometry on the removal function. Consequently, the current 2D convolution algorithm would influence the solution accuracy for the dwell time and reduce the convergence of the figuring process. In this part, based on the material removal characteristics of IBF, a mathematical model of the removal function is developed theoretically and verified experimentally. Research results show that the removal function during IBFof a curved surface is actually a dynamic function in the 2D convolution algorithm. The mathematical modeling of the dynamic removal function provides theoretical foundations for our proposed new algorithm in the next part, and final verification experiments indicate that this algorithm can effectively improve the accuracy of the dwell time solution for the IBFof curved surfaces.",
        "keywords": [
            ""
        ],
        "venue": "Applied Optics",
        "year": 2014,
        "id": "DYummFTw"
    },
    "BYf4chAe": {
        "authors": [
            {
                "name": "Wenlin Liao",
                "org": ""
            },
            {
                "name": "Yifan Dai",
                "org": ""
            },
            {
                "name": "Xuhui Xie",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            }
        ],
        "title": "Mathematical modeling and application of removal functions during deterministic ion beam figuring of optical surfaces. Part 2: Application",
        "abstract": "Ion beam figuring (IBF) is established for the final precision figuring of optical components. In this deterministic method, the figuring process is represented by a two-dimensional (2D) convolution operation of a constant removal function and the dwell time, where the figuring precision is guaranteed by the stability of the removal function as well as the solution accuracy of the dwell time. However, the current 2D convolution equation cannot factually reflect the IBF process of curved surfaces, which neglects the influence of the projection distortion and the workpiece geometry. Consequently, the current convolution algorithm for the IBF process would influence the solution accuracy for the dwell time and reduce the convergence of the figuring process. In this part, we propose an improved algorithm based on the mathematical modeling of the dynamic removal function in Part A, which provides a more accurate dwell time for IBF of a curved surface. Additionally, simulation analysis and figuring experiments are carried out to verify the feasibility of our proposed algorithm. The final experimental results indicate that the figuring precision and efficiency can be simultaneously improved by this method.",
        "keywords": [
            ""
        ],
        "venue": "Applied Optics",
        "year": 2014,
        "id": "BYf4chAe"
    },
    "AEfwQInN": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Hu'Nan Key Laboratory of Ultra-precision Machining Technology"
            },
            {
                "name": "Yifan Dai",
                "org": "Hu'Nan Key Laboratory of Ultra-precision Machining Technology"
            },
            {
                "name": "Xuhui Xie",
                "org": "Hu'Nan Key Laboratory of Ultra-precision Machining Technology"
            },
            {
                "name": "Wenlin Liao",
                "org": "Hu'Nan Key Laboratory of Ultra-precision Machining Technology"
            },
            {
                "name": "Shengyi Li",
                "org": "Hu'Nan Key Laboratory of Ultra-precision Machining Technology"
            }
        ],
        "title": "Translation-reduced ion beam figuring",
        "abstract": "A translation-reduced ion beam figuring (TRIBF) technique for five-axis ion beam figuring (IBF) plants is proposed to process large size components which cannot be processed in the traditional way. This novel technique enhances the capability of five-axis IBF plants by taking advantage of their rotation axes. The IBF kinematic model is described and the TRIBF processing technique is established by solving the motion parameters. Verification experiments are conducted on a 150 mm diameter planar mirror. This mirror was processed by TRIBF technique with only a 100 mm translation stage. The surface error was reduced from initial 10.7nm rms to 1.3nm rms within 97 minute processing time. The result indicates that the TRIBF processing technique is feasible and effective.",
        "keywords": [
            ""
        ],
        "venue": "Optics Express",
        "year": 2015,
        "id": "AEfwQInN"
    },
    "orG0q4bB": {
        "authors": [
            {
                "name": "Hong-Fei Deng",
                "org": "College of Mechatronics and Automation"
            },
            {
                "name": "Zheng Yuan",
                "org": "Chongqing Communication Institute"
            },
            {
                "name": "Xu-Hui Xie",
                "org": "College of Mechatronics and Automation"
            },
            {
                "name": "Lin Zhou",
                "org": "College of Mechatronics and Automation"
            },
            {
                "name": "Hao Hu",
                "org": "College of Mechatronics and Automation"
            }
        ],
        "title": "Simulation research on temperature field of KDP crystal and technical parameters optimization in ion beam figuring",
        "abstract": "To solve the problem of the thermal effect of IBF processing, the surface temperature and its distribution should be known, to decrease the temperature of optical component in the process of ion beam figuring. This paper established the model of the temperature field under ion beam bombardment, and simulated the process of ion beam figuring KDP crystal, and evolvements of temperature field going with technical parameters were simulated and investigated, based on ANSYS Parameter Design Language (APDL). The influence of technical parameters on the temperature of KDP crystal was analyzed, and optimized the technical parameters by orthogonal analysis. The optimization results show that, from the impact of the extent of the temperature of component, incidence angle \u03b8 > ion energy \u03b5 > peak beam current density J > coefficient of distance between scan paths \u03bc > parameter of beam radius \u03c3; To decrease temperature increment of component, ion beam figuring with lower ion energy and peak beam current density, larger beam radius, incidence angle and coefficient of distance between scan paths are advantage to decrease temperature of optics without prolonging machining time.",
        "keywords": [
            "Ion beam figuring (IBF)",
            "KDP crystal",
            "Parameters optimization",
            "Temperature field"
        ],
        "venue": "Rengong Jingti Xuebao/Journal of Synthetic Crystals",
        "year": 2015,
        "id": "orG0q4bB"
    },
    "NNVMwK9C": {
        "authors": [
            {
                "name": "Mourad Idir",
                "org": "NSLS-II"
            },
            {
                "name": "Lei Huang",
                "org": "NSLS-II"
            },
            {
                "name": "Nathalie Bouet",
                "org": "NSLS-II"
            },
            {
                "name": "Konstantine Kaznatcheev",
                "org": "NSLS-II"
            },
            {
                "name": "Matthew Vescovi",
                "org": "NSLS-II"
            },
            {
                "name": "Ken Lauer",
                "org": "NSLS-II"
            },
            {
                "name": "Ray Conley",
                "org": "Advanced Photon Source"
            },
            {
                "name": "Kent Rennie",
                "org": "Kaufman and Robinson Inc."
            },
            {
                "name": "Jim Kahn",
                "org": "Kaufman and Robinson Inc."
            },
            {
                "name": "Richard Nethery",
                "org": "Kaufman and Robinson Inc."
            },
            {
                "name": "Lin Zhou",
                "org": "Hu'nan Key Laboratory of Ultra-precision Machining Technology"
            }
        ],
        "title": "A one-dimensional ion beam figuring system for x-ray mirror fabrication",
        "abstract": "We report on the development of a one-dimensional Ion Beam Figuring (IBF) system for x-ray mirror polishing. Ion beam figuring provides a highly deterministic method for the final precision figuring of optical components with advantages over conventional methods. The system is based on a state of the art sputtering deposition system outfitted with a gridded radio frequency inductive coupled plasma ion beam source equipped with ion optics and dedicated slit developed specifically for this application. The production of an IBF system able to produce an elongated removal function rather than circular is presented in this paper, where we describe in detail the technical aspect and present the first obtained results.",
        "keywords": [
            ""
        ],
        "venue": "Review of Scientific Instruments",
        "year": 2015,
        "id": "NNVMwK9C"
    },
    "TivoQvNz": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Hu'nan Key Laboratory of Ultra-precision Machining Technology"
            },
            {
                "name": "Yifan Dai",
                "org": "Hu'nan Key Laboratory of Ultra-precision Machining Technology"
            },
            {
                "name": "Xuhui Xie",
                "org": "Hu'nan Key Laboratory of Ultra-precision Machining Technology"
            },
            {
                "name": "Shengyi Li",
                "org": "Hu'nan Key Laboratory of Ultra-precision Machining Technology"
            }
        ],
        "title": "Obliquely incident ion beam figuring",
        "abstract": "A new ion beam figuring (IBF) technique, obliquely incident IBF (OI-IBF), is proposed. In OI-IBF, the ion beam bombards the optical surface obliquely with an invariable incident angle instead of perpendicularly as in the normal IBF. Due to the higher removal rate in oblique incidence, the process time in OI-IBF can be significantly shortened. The removal rates at different incident angles were first tested, and then a test mirror was processed by OI-IBF. Comparison shows that in the OI-IBF technique with a 30 deg incident angle, the process time was reduced by 56.8%, while keeping the same figure correcting ability. The experimental results indicate that the OI-IBF technique is feasible and effective to improve the surface correction process efficiency.",
        "keywords": [
            "ion beam figuring",
            "optical fabrication",
            "polishing"
        ],
        "venue": "Optical Engineering",
        "year": 2015,
        "id": "TivoQvNz"
    },
    "B9hmekZV": {
        "authors": [
            {
                "name": "Qian Zhang",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology, Chongqing University"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology, Chongqing University"
            },
            {
                "name": "Luowei Zhou",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology, Chongqing University"
            },
            {
                "name": "Chao Liu",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology, Chongqing University"
            },
            {
                "name": "Lefeng Shi",
                "org": "State Grid Chongqing Electric Power Co. Electric Power Research Institute"
            }
        ],
        "title": "Load frequency control considering charging and discharging static frequency characteristics of electric vehicles",
        "abstract": "Currently, researches on electric vehicles for frequency regulation in power system, mainly regard them as distributed generation, while relatively few take them as controllable load. However, electric vehicles are equally important either as distributed generation or as controllable load in frequency regulation. Therefore, a model with charging and discharging static frequency characteristics of electric vehicles is developed first. Then, a charging and discharging coordinated control strategy for electric vehicles is proposed to realize their role conversion between distributed generation and controllable load. Finally, considering charging and discharging of electric vehicles, a load frequency control model each for single and two-area power systems is developed. A simulation study is carried out to demonstrate that electric vehicles for frequency regulation as distributed generation and controllable load, can not only effectively improve power system responsiveness and reduce frequency deviation, but also remarkably decrease the reserve capacity of traditional frequency regulation units.",
        "keywords": [
            "Controllable load",
            "Distributed generator",
            "Electric vehicle",
            "Load frequency control",
            "Power system frequency regulation",
            "Vehicle-to-grid (V2G)"
        ],
        "venue": "Dianli Xitong Zidonghua/Automation of Electric Power Systems",
        "year": 2014,
        "id": "B9hmekZV"
    },
    "zsL62PRT": {
        "authors": [
            {
                "name": "Qian Zhang",
                "org": "State Key Laboratory of Power Transmission Equipment & System Security and New Technology, Chongqing University"
            },
            {
                "name": "Chao Liu",
                "org": "State Key Laboratory of Power Transmission Equipment & System Security and New Technology, Chongqing University"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Power Transmission Equipment & System Security and New Technology, Chongqing University"
            },
            {
                "name": "Chunyan Li",
                "org": "State Key Laboratory of Power Transmission Equipment & System Security and New Technology, Chongqing University"
            },
            {
                "name": "Xi Gan",
                "org": "State Grid Pixian Power Supply Co. Ltd."
            }
        ],
        "title": "A bi-level economy dispatch model considering temporal and spatial optimal distribution of electric vehicles",
        "abstract": "To study the influence of large-scale plug-in electric vehicles (EVs) on the power grid, a bi-level economy dispatch optimization model based on vehicle-to-grid (V2G) is presented. Based on the traditional security constrained unit commitment, the spatial and temporal distribution characteristics of electric vehicles are also taken into account. The model is then separated into two sub-models, i.e. the unit commitment model and the EV charging and discharging scheduling model. The model can be solved by the particle swarm optimization algorithm and the linear programming algorithm based on the Newton-Raphson power flow algorithm, Results show that the next-day unit commitment scheme and electric vehicle best charging and discharging schemes of each time interval are obtained through the model proposed. Furthermore, this model can realize real-time optimal control during 24 hours and allot the V2G dispatch plan to each access node spatially, which is instructive for the layout of the charging station. It can reduce network loss and the peak-to-valley load difference at minimal generation cost.",
        "keywords": [
            "Charging and discharging scheduling",
            "Electric vehicle",
            "Optimal dispatching",
            "Temporal and spatial distribution",
            "Unit commitment"
        ],
        "venue": "Dianli Xitong Zidonghua/Automation of Electric Power Systems",
        "year": 2014,
        "id": "zsL62PRT"
    },
    "UdDRubG8": {
        "authors": [
            {
                "name": "Zhi-Guo Zhang",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology, Chongqing University"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology, Chongqing University"
            },
            {
                "name": "Ming Yang",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology, Chongqing University"
            },
            {
                "name": "Ke Guo",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology, Chongqing University"
            }
        ],
        "title": "Isolated switching circuit based on DCM for high-voltage power supply applications",
        "abstract": "A switching circuit with a high conversion ratio is proposed in this paper, due to the fact that it is difficult for the basic line frequency voltage-multiplying rectifier to keep its output voltage constant when the load varies, and its windings and volume of the set-up transformer are large. The proposed circuit operated in discontinuous conduction mode, and its operation was divided into three subintervals. The steady-state gain function for output voltage verse input voltage was derivate by virtual capacitor method and average modeling. The switching circuit combined merits of the voltage-multiplier with flyback converters. It was very suitable for low-power high-voltage power applications where small size and high conversion ratio were needed. The operations and prominent characteristics of the converter were described. A laboratory prototype was built based on the analysis. The effectiveness of proposed approach is verified by experimental results.",
        "keywords": [
            "Discontinuous conduction mode synchronous",
            "Flyback converters",
            "High-voltage power supply",
            "Voltage-multiplier rectifiering"
        ],
        "venue": "Dianji yu Kongzhi Xuebao/Electric Machines and Control",
        "year": 2014,
        "id": "UdDRubG8"
    },
    "ym07qhzp": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology, Chongqing University"
            },
            {
                "name": "Mi Zhang",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology, Chongqing University"
            }
        ],
        "title": "Analysis of resonance phenomenon in large-scale photovoltaic power plant",
        "abstract": "The Norton equivalent model of large-scale photovoltaic power plant is established, the expression formulas are deduced for the inverter output current and the voltage at grid-connection point, and the influences of grid impedance composed of the reactive power compensation device, Boost transformer leakage inductance and transmission line impedance on the power quality and the resonance phenomenon in the parallel system of three-phase photovoltaic inverter are analyzed. A simulation model of power system is built for validating the theoretical analysis and results show that, there is resonance phenomenon in the system, which is induced by the grid impedance and causes the decrease of its power quality. Compared with the increase of transmission distance, the increase of photovoltaic capacity does more likely reduce the power quality of system, while compared with the inverter output current, the voltage at grid-connection point has much higher THD and its harmonic component does more likely exceed the standard.",
        "keywords": [
            "Electric inverters",
            "Electric power plants",
            "Grid impedance",
            "Models",
            "Norton equivalent model",
            "Photovoltaic",
            "Power quality",
            "Resonance"
        ],
        "venue": "Dianli Zidonghua Shebei/Electric Power Automation Equipment",
        "year": 2014,
        "id": "ym07qhzp"
    },
    "fojUC5n7": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Power Transmission Equipment & System Security and New Technology"
            },
            {
                "name": "Wei Ren",
                "org": "State Key Laboratory of Power Transmission Equipment & System Security and New Technology"
            },
            {
                "name": "Bo Liao",
                "org": "Sichuan Electric Power Design & Consulting Co."
            },
            {
                "name": "Yang Chao",
                "org": "State Key Laboratory of Power Transmission Equipment & System Security and New Technology"
            },
            {
                "name": "Nianbin Shao",
                "org": "State Key Laboratory of Power Transmission Equipment & System Security and New Technology"
            },
            {
                "name": "Xiao Du",
                "org": "State Key Laboratory of Power Transmission Equipment & System Security and New Technology"
            }
        ],
        "title": "Reactive power and voltage control for grid-connected PV power plants",
        "abstract": "Grid-connected PV plants should have independent control of reactive power to support the grid. The equivalent aggregation model of large-scale photovoltaic (PV) plants is established firstly. With the existence of the line and transformer impedance, the grid voltage stability is reduced caused without the reactive power compensation device in PV plants and reactive power of the inverter. The three-level reactive power control strategy is proposed based on the cooperated control between the reactive power compensation device and the inverter. The strategy coordinates the reactive power output among the reactive power compensation devices, PV generation unit and inverters, which regulates the voltage very effectively. Then the grid active and reactive power losses can be minimized while maintaining the voltage in the required range. In order to ensure the stable operation of the grid, the PV array carries out lower power operation strategy when the reactive power output of PV plants is fixed. Moreover, the validity and the effectiveness of the method are validated by means of simulation results.",
        "keywords": [
            "Grid-connected inverter",
            "PV plants",
            "Reactive power compensation",
            "Sensitivity",
            "Voltage control"
        ],
        "venue": "Diangong Jishu Xuebao/Transactions of China Electrotechnical Society",
        "year": 2015,
        "id": "fojUC5n7"
    },
    "zkFNlAGN": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology, Chongqing University"
            },
            {
                "name": "Mi Zhang",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology, Chongqing University"
            },
            {
                "name": "Ming Yang",
                "org": "State Key Laboratory of Power Transmission Equipment and System Security and New Technology, Chongqing University"
            },
            {
                "name": "Guoqing He",
                "org": "China Electric Power Research Institute"
            }
        ],
        "title": "Controller design of three-phase inverter with lcl filter considering the grid impedance",
        "abstract": "The stability of the three-phase PV inverter with LCL filter and corresponding control strategy were researched considering the grid impedance. First, the grid-connected PV inverter stability was analyzed of grid impedance. Then the inverter control strategy was proposed based on state feedback to achieve the system poles assignment thereby inhibiting the effect on the system power quality and stability considering the grid impedance. Finally the study was validated through simulation. Studies have shown that: the grid impedance can decrease the LCL filter resonance frequency and the PV system with PR+HC controller becomes unstable, severely reducing the power quality; the proposed pole-assignment control strategy can effectively inhibit the grid impedance impact on system stability.",
        "keywords": [
            "Grid impedance",
            "LCL filter",
            "Pole assignment",
            "PV inverter",
            "Stability"
        ],
        "venue": "Taiyangneng Xuebao/Acta Energiae Solaris Sinica",
        "year": 2015,
        "id": "zkFNlAGN"
    },
    "etSThnPi": {
        "authors": [
            {
                "name": "Xu Cheng",
                "org": "School of Information Science and Engineering, Southeast University"
            },
            {
                "name": "Ni-Jun Li",
                "org": "School of Information Science and Engineering, Southeast University"
            },
            {
                "name": "Tong-Chi Zhou",
                "org": "School of Information Science and Engineering, Southeast University"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Information Science and Engineering, Southeast University"
            },
            {
                "name": "Zhen-Yang Wu",
                "org": "School of Information Science and Engineering, Southeast University"
            }
        ],
        "title": "Online tracking via superpixel and sparse representation",
        "abstract": "Handling appearance variations is a very challenging issue for visual tracking. In this paper, an effective superpixel based L1 tracking method (SuperPixel-L1 tracker, SPL1) is proposed to deal with the above problem in a particle filter framework. First, the mid-level visual cue with structural information is exploited to construct the dictionary and model the object appearance. Then each candidate state defined by a particle is solved via L1 minimization. The candidate with the smallest reconstruction error is selected as the tracking result. Finally, the online dictionary updating strategy is further improved. The dictionary needs to be updated regardless of whether the object is occluded or not. The initial frame information is retained during the updating process to reduce the possibility of the object drift. Simulation results show that SPL1 tracker can still stably track the object under the circumstance of long-term occlusion, large scale and illumination changes.",
        "keywords": [
            "Appearance changes",
            "Online learning",
            "Sparse representation",
            "Superpixel",
            "Visual tracking"
        ],
        "venue": "Dianzi Yu Xinxi Xuebao/Journal of Electronics and Information Technology",
        "year": 2014,
        "id": "etSThnPi"
    },
    "L2wy23Pu": {
        "authors": [
            {
                "name": "Xu Cheng",
                "org": ""
            },
            {
                "name": "Haiyan Guo",
                "org": ""
            },
            {
                "name": "Nijun Li",
                "org": ""
            },
            {
                "name": "Tongchi Zhou",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Zhenyang Wu",
                "org": ""
            }
        ],
        "title": "Local discriminative tracking algorithm based on superpixel",
        "abstract": "To solve the drifting problem of objects caused by external disturbances under complex circumstances, a local discriminative tracking method based on superpixel is proposed. First, the objects from the first ten frames of a video are segmented into superpixels, which are clustered by the k-means algorithm to construct the initial dictionary. Secondly, a linear classifier is trained by the training sample set. Then, to reduce the possibility of the object drifting, the likelihood function is defined as a linear weighted combination of the initial classifier and the updated classifier. Finally, under the particle filter framework, the particle with the highest likelihood confidence is considered as the tracking result. The dictionary and the parameters of the classifier are updated once every U frames to capture the variation of the object appearance. The simulation results show that the proposed algorithm can track the object under the complex circumstance with object occlusion and illumination change.",
        "keywords": [
            "Appearance updating",
            "Object tracking",
            "Sparse representation",
            "Superpixel",
            "Video surveillance"
        ],
        "venue": "Dongnan Daxue Xuebao (Ziran Kexue Ban)/Journal of Southeast University (Natural Science Edition)",
        "year": 2014,
        "id": "L2wy23Pu"
    },
    "FrcyJ9vx": {
        "authors": [
            {
                "name": "Haiyan Guo",
                "org": "College of Engineering, Nanjing Agricultural University"
            },
            {
                "name": "Xiaoxiong Li",
                "org": "School of Information Science and Engineering, Southeast University"
            },
            {
                "name": "Nijun Li",
                "org": "School of Information Science and Engineering, Southeast University"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Information Science and Engineering, Southeast University"
            },
            {
                "name": "Zhenyang Wu",
                "org": "School of Information Science and Engineering, Southeast University"
            }
        ],
        "title": "Single-channel speech separation based on pitch state and interframe correlation",
        "abstract": "A single-channel speech separation algorithm based on pitch state and interframe correlation is proposed. First, the pitch of two simultaneously active speakers is tracked from mixture over time and encoded by pitch states. On this basis, adaptive source-individual dictionaries are generated to distinguish source frames in pitch. Secondly, a frequent pattern mining method is utilized to find the frequent 1-itemset as atoms to reduce the sizes of the dictionaries generated for the sources whose pitch states are 1. Thirdly, based on the separated sources achieved by the orthogonal matching pursuit (OMP) algorithm, mixed frames with poor separation performance are detected. Each is added with the shifted separated source frame which is the most correlated one among all the shifted waveforms of adjacent separated sources, and the soft mask method is adopted to perform the second separation. The experimental results show that the proposed algorithm outperforms two classical separation methods in terms of signal-to-noise ratio (SNR). Besides, the frequent pattern mining method can greatly reduce the computation cost of the separation algorithm.",
        "keywords": [
            "Data mining",
            "Orthogonal matching pursuit (OMP)",
            "Pitch frequency",
            "Sparse decomposition",
            "Speech separation"
        ],
        "venue": "Dongnan Daxue Xuebao (Ziran Kexue Ban)/Journal of Southeast University (Natural Science Edition)",
        "year": 2014,
        "id": "FrcyJ9vx"
    },
    "JFT85d5G": {
        "authors": [
            {
                "name": "Xiaoyan Zhao",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Zhenyang Wu",
                "org": ""
            }
        ],
        "title": "Compressed sensing-based sound source localization algorithm for microphone array",
        "abstract": "To improve the sound source localization performance of microphone arrays under the conditions with high reverberation and low signal-to-noise ratio (SNR), a compressed sensing-based sound source localization algorithm is proposed. In the proposed algorithm, the problem of sound source localization is converted to the reconstruction problem of sparse signal, and the room impulse responses at different locations are treated as the features used to construct the dictionary. First, the received signals of the microphone array are transformed to the frequency domain, and a set of extended source signal vectors in the frequency domain, which contain the location information of the sound source, are calculated from the frequency components with higher power. Then, the extended source signal vectors are integrated in the frequency domain to enhance the location information of the sound source, and the spatial location corresponding to the maximum element of the integrated vector is the location estimation of the sound source. The simulation results show that compared with the steered response power-phase transform (SRP-PHAT) localization algorithm, the proposed algorithm has a higher localization rate, and is more robust against reverberation and more suitable for location estimation under the conditions with high reverberation and low SNR.",
        "keywords": [
            "Compressed sensing",
            "Microphone array",
            "Sound source localization"
        ],
        "venue": "Dongnan Daxue Xuebao (Ziran Kexue Ban)/Journal of Southeast University (Natural Science Edition)",
        "year": 2015,
        "id": "JFT85d5G"
    },
    "GRA8hOOj": {
        "authors": [
            {
                "name": "Xu Cheng",
                "org": "School of Information Science and Engineering, Southeast University"
            },
            {
                "name": "Nijun Li",
                "org": "School of Information Science and Engineering, Southeast University"
            },
            {
                "name": "Tongchi Zhou",
                "org": "School of Information Science and Engineering, Southeast University"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Information Science and Engineering, Southeast University"
            },
            {
                "name": "Zhenyang Wu",
                "org": "School of Information Science and Engineering, Southeast University"
            }
        ],
        "title": "Robust superpixel tracking with weighted multiple-instance learning",
        "abstract": "This paper proposes a robust superpixel-based tracker via multiple-instance learning, which exploits the importance of instances and mid-level features captured by superpixels for object tracking. We first present a superpixels-based appearance model, which is able to compute the confidences of the object and background. Most importantly, we introduce the sample importance into multiple-instance learning (MIL) procedure to improve the performance of tracking. The importance for each instance in the positive bag is defined by accumulating the confidence of all the pixels within the corresponding instance. Furthermore, our tracker can help recover the object from the drifting scene using the appearance model based on superpixels when the drift occurs. We retain the first (k-1) frames' information during the updating process to alleviate drift to some extent. To evaluate the effectiveness of the proposed tracker, six video sequences of different challenging situations are tested. The comparison results demonstrate that the proposed tracker has more robust and accurate performance than six ones representing the state-of-the-art.",
        "keywords": [
            "Appearance model",
            "Multiple instance learning",
            "Superpixel",
            "Visual tracking"
        ],
        "venue": "IEICE Transactions on Information and Systems",
        "year": 2015,
        "id": "GRA8hOOj"
    },
    "ckb2wZuq": {
        "authors": [
            {
                "name": "Tongchi Zhou",
                "org": ""
            },
            {
                "name": "Xu Cheng",
                "org": ""
            },
            {
                "name": "Nijun Li",
                "org": ""
            },
            {
                "name": "Qinjun Xu",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Zhenyang Wu",
                "org": ""
            }
        ],
        "title": "Action recognition using a hierarchy of feature groups",
        "abstract": "To improve the recognition performance of video human actions, an approach that models the video actions in a hierarchical way is proposed. This hierarchical model summarizes the action contents with different spatio-temporal domains according to the properties of human body movement. First, the temporal gradient combined with the constraint of coherent motion pattern is utilized to extract stable and dense motion features that are viewed as point features, then the mean-shift clustering algorithm with the adaptive scale kernel is used to label these features. After pooling the features with the same label to generate part-based representation, the visual word responses within one large scale volume are collected as video object representation. On the benchmark KTH(Kungliga Tekniska H\u00f6gskolan) and UCF(University of Central Florida)-sports action datasets, the experimental results show that the proposed method enhances the representative and discriminative power of action features, and improves recognition rates. Compared with other related literature, the proposed method obtains superior performance.",
        "keywords": [
            "Action recognition",
            "Coherent motion pattern",
            "Feature groups",
            "Part-based representation"
        ],
        "venue": "Journal of Southeast University (English Edition)",
        "year": 2015,
        "id": "ckb2wZuq"
    },
    "av62Q8i8": {
        "authors": [
            {
                "name": "Xu Cheng",
                "org": "School of Information Science and Engineering, Southeast University"
            },
            {
                "name": "Nijun Li",
                "org": "School of Information Science and Engineering, Southeast University"
            },
            {
                "name": "Tongchi Zhou",
                "org": "School of Information Science and Engineering, Southeast University"
            },
            {
                "name": "Zhenyang Wu",
                "org": "School of Information Science and Engineering, Southeast University"
            },
            {
                "name": "Lin Zhou",
                "org": "School of Information Science and Engineering, Southeast University"
            }
        ],
        "title": "Multi-task object tracking with feature selection",
        "abstract": "In this paper, we propose an efficient tracking method that is formulated as a multi-task reverse sparse representation problem. The proposed method learns the representation of all tasks jointly using a customized APG method within several iterations. In order to reduce the computational complexity, the proposed tracking algorithm starts from a feature selection scheme that chooses suitable number of features from the object and background in the dynamic environment. Based on the selected feature, multiple templates are constructed with a few candidates. The candidate that corresponds to the highest similarity to the object templates is considered as the final tracking result. In addition, we present a template update scheme to capture the appearance changes of the object. At the same time, we keep several earlier templates in the positive template set unchanged to alleviate the drifting problem. Both qualitative and quantitative evaluations demonstrate that the proposed tracking algorithm performs favorably against the state-of-the-art methods.",
        "keywords": [
            "Feature selection",
            "Multi-task learning",
            "Sparse representation",
            "Visual tracking"
        ],
        "venue": "IEICE Transactions on Fundamentals of Electronics, Communications and Computer Sciences",
        "year": 2015,
        "id": "av62Q8i8"
    },
    "agWqVbHT": {
        "authors": [
            {
                "name": "Ao Wang",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials, School of Chemistry and Materials Science, Nanjing Normal University"
            },
            {
                "name": "Yejing Li",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials, School of Chemistry and Materials Science, Nanjing Normal University"
            },
            {
                "name": "Lin Zhou",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials, School of Chemistry and Materials Science, Nanjing Normal University"
            },
            {
                "name": "Linxin Yuan",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials, School of Chemistry and Materials Science, Nanjing Normal University"
            },
            {
                "name": "Shan Lu",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials, School of Chemistry and Materials Science, Nanjing Normal University"
            },
            {
                "name": "Yun Lin",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials, School of Chemistry and Materials Science, Nanjing Normal University"
            },
            {
                "name": "Jiahong Zhou",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials, School of Chemistry and Materials Science, Nanjing Normal University"
            },
            {
                "name": "Shaohua Wei",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials, School of Chemistry and Materials Science, Nanjing Normal University"
            }
        ],
        "title": "Charge dependent photodynamic activity of alanine based zinc phthalocyanines",
        "abstract": "In this paper, to minimize the effects of different structure, three alanine-based zinc phthalocyanines (Pcs) of differing charges were engineered and synthesized with the same basic structure. On this premise, the relationship between nature of charge and photodynamic activity was studied. Besides, further verification and explanation of some inconsistent results were also carried out. The results showed that charge can influence the aggregation state, singlet oxygen generation ability and cellular uptake of Pcs, thereby affecting their photodynamic activity. In addition, the biomolecules inside cells may interact with Pcs of differing charges, which can also influence the aggregation state and singlet oxygen generation of the Pcs, and then influence the relationship between nature of charge and photodynamic activity.",
        "keywords": [
            "Aggregation state",
            "Alanine based zinc phthalocyanine",
            "Charge",
            "Photodynamic activity",
            "Photosensitizer",
            "Singlet oxygen"
        ],
        "venue": "Journal of Photochemistry and Photobiology B: Biology",
        "year": 2014,
        "id": "agWqVbHT"
    },
    "xjbJILFf": {
        "authors": [
            {
                "name": "Ao Wang",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials, School of Chemistry and Materials Science, Nanjing Normal University"
            },
            {
                "name": "Xianglan Chen",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials, School of Chemistry and Materials Science, Nanjing Normal University"
            },
            {
                "name": "Liu Zhang",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials, School of Chemistry and Materials Science, Nanjing Normal University"
            },
            {
                "name": "Guangyi Zhang",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials, School of Chemistry and Materials Science, Nanjing Normal University"
            },
            {
                "name": "Lin Zhou",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials, School of Chemistry and Materials Science, Nanjing Normal University"
            },
            {
                "name": "Shan Lu",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials, School of Chemistry and Materials Science, Nanjing Normal University"
            },
            {
                "name": "Jiahong Zhou",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials, School of Chemistry and Materials Science, Nanjing Normal University"
            },
            {
                "name": "Shaohua Wei",
                "org": "Jiangsu Key Laboratory of Biofunctional Materials, School of Chemistry and Materials Science, Nanjing Normal University"
            }
        ],
        "title": "Effects of pH on aggregation and photodynamic activities of cationic zinc phthalocyanines substituted with amides",
        "abstract": "This work reports on the effects of pH (especially base addition) on the properties of two cationic phthalocyanines substituted with amide groups. The absorption spectra, photo-stability, singlet oxygen generation ability and photodegradation of CT DNA of the two cationic phthalocyanines in different pH were studied and compared. Results indicated that the base additive can promote a shift in the amide/imidohydrine balance toward imidohydrine, which resulted in the reduction of aggregate and enhancement of photodynamic activities. This base induced tautomeric transformation could be a novel way to generate low aggregated and high photodynamic efficiency cationic Pcs. \u00a9 2014 Elsevier B.V.",
        "keywords": [
            "Aggregate",
            "Amide",
            "Cationic phthalocyanines",
            "pH",
            "Photodynamic activity",
            "Tautomeric transformation"
        ],
        "venue": "Journal of Photochemistry and Photobiology A: Chemistry",
        "year": 2014,
        "id": "xjbJILFf"
    },
    "VrX9qn0u": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "College of Chemistry and Materials Science, Jiangsu Key Laboratory of Biofunctional Materials, Nanjing Normal University"
            },
            {
                "name": "Xuefeng Ge",
                "org": "College of Chemistry and Materials Science, Jiangsu Key Laboratory of Biofunctional Materials, Nanjing Normal University"
            },
            {
                "name": "Jiahong Zhou",
                "org": "College of Chemistry and Materials Science, Jiangsu Key Laboratory of Biofunctional Materials, Nanjing Normal University"
            },
            {
                "name": "Shaohua Wei",
                "org": "College of Chemistry and Materials Science, Jiangsu Key Laboratory of Biofunctional Materials, Nanjing Normal University"
            },
            {
                "name": "Jian Shen",
                "org": "College of Chemistry and Materials Science, Jiangsu Key Laboratory of Biofunctional Materials, Nanjing Normal University"
            }
        ],
        "title": "Modulating the photo-exciting process of photosensitizer to improve in vitro phototoxicity by preparing its self-assembly nanostructures",
        "abstract": "A series of hypocrellin A (HA) self-assembled nanostructures were prepared by controlling the charge properties of drugs and the ion strength of the environment. Comparative studies with nanostructures and HA have demonstrated that the self-assembled effect on the HA molecule significantly enhances its water dispersion ability, ",
        "keywords": [
            ""
        ],
        "venue": "RSC Advances",
        "year": 2015,
        "id": "VrX9qn0u"
    },
    "CGJpe3xy": {
        "authors": [
            {
                "name": "Xianglan Chen",
                "org": ""
            },
            {
                "name": "Yejing Li",
                "org": ""
            },
            {
                "name": "Ao Wang",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Shan Lu",
                "org": ""
            },
            {
                "name": "Jiahong Zhou",
                "org": ""
            },
            {
                "name": "Yun Lin",
                "org": ""
            },
            {
                "name": "Shaohua Wei",
                "org": ""
            }
        ],
        "title": "Protonation salt derivative with heavy-atom effect on phthalocyanine for enhanced in vitro photodynamic therapy",
        "abstract": "In order to improve water-solubility and photodynamic activity of 2(3), 9(10), 16(17), 23(24)-tetra-((amino)methyl)phenoxy)phthalocyaninato-zinc (ZnPc) simultaneously, here, we present the first attempt to introduce heavy atoms (Br and I) to ZnPc though a simple method by synthesizing the hydrobromide and hydriodate protonation salt derivatives of ZnPc. Researches indicated that these protonation salt derivatives of ZnPc can stably disperse in aqueous system for a long time. Furthermore, the internal heavy atom effect from hydriodate in the ZnPc molecules enhances the intersystem crossing (ISC) efficiency of ZnPc during its photo-exciting process. Therefore, the generation of reactive oxygen species (ROSs), especially singlet oxygen (",
        "keywords": [
            "Anticancer activity",
            "Heavy atom heavy",
            "Photodynamic therapy",
            "Phthalocyanine",
            "Polyamine",
            "Water solubility"
        ],
        "venue": "Dyes and Pigments",
        "year": 2015,
        "id": "CGJpe3xy"
    },
    "yxTDZAv4": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Xuefeng Ge",
                "org": ""
            },
            {
                "name": "Jiahong Zhou",
                "org": ""
            },
            {
                "name": "Shaohua Wei",
                "org": ""
            },
            {
                "name": "Jian Shen",
                "org": ""
            }
        ],
        "title": "Multicolor imaging and the anticancer effect of a bifunctional silica nanosystem based on the complex of graphene quantum dots and hypocrellin A",
        "abstract": "An effective theranostic platform based on porous silica nanoparticles encapsulated with the complex of a photodynamic anticancer drug and graphene quantum dots (GQDs), with the bifunction of multicolor imaging and satisfactory photo-induced anticancer activity, was successfully designed and prepared for in vitro photodynamic therapy (PDT) of superficial cancer. This journal is",
        "keywords": [
            ""
        ],
        "venue": "Chemical Communications",
        "year": 2015,
        "id": "yxTDZAv4"
    },
    "EykbJt2x": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Department of Cardiology, Tongji Hospital, Tongji University School of Medicine"
            },
            {
                "name": "Haoming Song",
                "org": "Department of Cardiology, Tongji Hospital, Tongji University School of Medicine"
            },
            {
                "name": "Wenjun Xu",
                "org": "Department of Cardiology, Tongji Hospital, Tongji University School of Medicine"
            },
            {
                "name": "Jiahong Xu",
                "org": "Department of Cardiology, Tongji Hospital, Tongji University School of Medicine"
            },
            {
                "name": "Jinfa Jiang",
                "org": "Department of Cardiology, Tongji Hospital, Tongji University School of Medicine"
            },
            {
                "name": "Zhu Gong",
                "org": "Department of Cardiology, Tongji Hospital, Tongji University School of Medicine"
            },
            {
                "name": "Yang Liu",
                "org": "Department of Cardiology, Tongji Hospital, Tongji University School of Medicine"
            },
            {
                "name": "Wenwen Yan",
                "org": "Department of Cardiology, Tongji Hospital, Tongji University School of Medicine"
            },
            {
                "name": "Lemin Wang",
                "org": "Department of Cardiology, Tongji Hospital, Tongji University School of Medicine"
            }
        ],
        "title": "Immune function of peripheral T cells in patients with venous thromboembolism or coronary artery atherosclerosis",
        "abstract": "Introduction and Objectives: Recent studies have shown that the major risk factors for arterial thrombotic diseases are closely associated with venous thromboembolism (VTE). This study aimed to investigate the expression of CD3, CD4 and CD8 in T lymphocytes, the CD4/CD8 ratio and high-sensitivity C-reactive protein (hs-CRP) levels in patients with VTE, coronary artery atherosclerosis (CAA) and healthy subjects. Methods: A total of 82 healthy subjects, 51 VTE patients and 114 CAA patients were recruited, and the expression of CD3, CD4 and CD8 in T lymphocytes and the CD4/CD8 ratio were determined. Serum hs-CRP was also measured. Results: Compared to healthy subjects, VTE patients had significantly reduced CD3 expression (p=0.019), comparable CD4 expression (p=0.868), significantly reduced CD8 expression (p<0.001) and increased CD4/CD8 ratio (p=0.044). However, VTE patients had comparable expression of CD3, CD4 and CD8 and CD4/CD8 ratio to CAA patients. In addition, among patients with VTE or CAA, the proportion of patients with reduced CD3+ and CD8+ T lymphocytes or increased CD4/CD8 ratio was significantly higher than in healthy subjects. In addition, hs-CRP in both VTE and CAA groups was significantly higher than in healthy subjects. Conclusions: The antigen recognition and signal transduction activation of T cells is significantly reduced in patients with VTE or CAA, and the killing effect of T cells on pathogens, including viruses, is also significantly compromised. In addition, inflammatory and immune mechanisms are involved in the occurrence and development of venous and arterial thrombosis. \u00a9 2013 Sociedade Portuguesa de Cardiologia.",
        "keywords": [
            "Coronary atherosclerosis",
            "Immune function",
            "T cell",
            "Venous thromboembolism"
        ],
        "venue": "Revista Portuguesa de Cardiologia",
        "year": 2014,
        "id": "EykbJt2x"
    },
    "aFVFYANY": {
        "authors": [
            {
                "name": "Yu Mao",
                "org": "Division of Cardiology, Tongji Hospital, Tongji University School of Medicine"
            },
            {
                "name": "Xiaolong Qi",
                "org": "Institute of Digestive Disease, Tongji Hospital, Tongji University School of Medicine"
            },
            {
                "name": "Lin Zhou",
                "org": "Division of Cardiology, Tongji Hospital, Tongji University School of Medicine"
            }
        ],
        "title": "Letter by Mao et al Regarding Article, \"noninvasive fractional flow reserve derived from computed tomography angiography for coronary lesions of intermediate stenosis severity: Results from the DeFACTO study\"",
        "abstract": "",
        "keywords": [
            ""
        ],
        "venue": "Circulation: Cardiovascular Imaging",
        "year": 2014,
        "id": "aFVFYANY"
    },
    "Hp8tYVJ8": {
        "authors": [
            {
                "name": "Xiaolong Qi",
                "org": ""
            },
            {
                "name": "Mingxin Xu",
                "org": ""
            },
            {
                "name": "Haitao Yang",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Yu Mao",
                "org": ""
            },
            {
                "name": "Haoming Song",
                "org": ""
            },
            {
                "name": "Quan Li",
                "org": ""
            },
            {
                "name": "Changqing Yang",
                "org": ""
            }
        ],
        "title": "Comparing mortality and myocardial infarction between coronary artery bypass grafting and drugeluting stenting in patients with diabetes mellitus and multivessel coronary artery disease: A meta-analysis",
        "abstract": "Introduction: We aim to compare the midterm outcomes between coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) in diabetic patients who had multivessel coronary artery diseases (CAD). Material and methods: A comprehensive literature search was conducted to identify the related clinical studies with a follow-up for 1 year at least. The endpoints were death, myocardial infarction, and major adverse cardiac and cerebrovascular events (MACCE). Results: Finally, the analysis of ten studies involving 5,264 patients showed that patients with CABG had worse baseline characteristics, a higher rate of stable angina pectoris, a higher percentage of triple-vessel disease, higher incidence of chronic total occlusion and a higher SYNTAX score. However, there was no significant difference in mortality between the two groups. Additionally, the rates of myocardial infarction and MACCE were markedly decreased in the CABG group. Conclusions: The strategy of CABG is better than PCI for diabetic patients with multivessel CAD. The CABG can significantly reduce the rates of myocardial infarction and MACCE and is comparable in mortality despite the worse baseline characteristics. \u00a9 2014 Termedia & Banach.",
        "keywords": [
            "Coronary artery bypass grafting",
            "Coronary artery diseases",
            "Percutaneous coronary intervention"
        ],
        "venue": "Archives of Medical Science",
        "year": 2014,
        "id": "Hp8tYVJ8"
    },
    "sTf5kUJE": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Division of Cardiology, Tongji Hospital, Tongji University School of Medicine"
            },
            {
                "name": "Xiao-Long Qi",
                "org": "Division of Gastroenterology and Hepatology, Tongji Hospital, Tongji University School of Medicine"
            },
            {
                "name": "Ming-Xin Xu",
                "org": "Division of Gastroenterology and Hepatology, Tongji Hospital, Tongji University School of Medicine"
            },
            {
                "name": "Yu Mao",
                "org": "Division of Cardiology, Tongji Hospital, Tongji University School of Medicine"
            },
            {
                "name": "Ming-Lin Liu",
                "org": "Section of Endocrinology, Diabetes and Metabolism, Temple University School of Medicine"
            },
            {
                "name": "Hao-Ming Song",
                "org": "Division of Cardiology, Tongji Hospital, Tongji University School of Medicine"
            }
        ],
        "title": "Microparticles: New light shed on the understanding of venous thromboembolism",
        "abstract": "Microparticles are small membrane fragments shed primarily from blood and endothelial cells during either activation or apoptosis. There is mounting evidence suggesting that microparticles perform a large array of biological functions and contribute to various diseases. Of these disease processes, a significant link has been established between microparticles and venous thromboembolism. Advances in research on the role of microparticles in thrombosis have yielded crucial insights into possible mechanisms, diagnoses and therapeutic targets of venous thromboembolism. In this review, we discuss the definition and properties of microparticles and venous thromboembolism, provide a synopsis of the evidence detailing the contributions of microparticles to venous thromboembolism, and propose potential mechanisms, by which venous thromboembolism occurs. Moreover, we illustrate a possible role of microparticles in cancer-related venous thromboembolism.",
        "keywords": [
            ""
        ],
        "venue": "Acta Pharmacologica Sinica",
        "year": 2014,
        "id": "sTf5kUJE"
    },
    "NayxFxMp": {
        "authors": [
            {
                "name": "Shengfang Chen",
                "org": "Department of Clinical Nutrition, Tongji Hospital of Tongji University"
            },
            {
                "name": "Ping Wu",
                "org": "Department of Clinical Nutrition, Tongji Hospital of Tongji University"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Cardiology, Tongji Hospital of Tongji University"
            },
            {
                "name": "Yuqin Shen",
                "org": "Department of Cardiology, Tongji Hospital of Tongji University"
            },
            {
                "name": "Yunjie Li",
                "org": "Department of Clinical Nutrition, Tongji Hospital of Tongji University"
            },
            {
                "name": "Haoming Song",
                "org": "Department of Cardiology, Tongji Hospital of Tongji University"
            }
        ],
        "title": "Relationship between increase of serum homocysteine caused by smoking and oxidative damage in elderly patients with cardiovascular disease",
        "abstract": "Background: To investigate the mechanism of smoking on cardiovascular diseases. Material and methods: 576 elderly patients with cardiovascular diseases in stable condition were consecutive recruited, asked about the living habits and smoking history in a way of face to face. Results: Of all the enrolled patients, current smoking rate was 34.8% for males and 3.4% for females. Average smoking quantity was 17 cigarettes per day and incidence of hyperhomocysteinemia was 38.0%. The homocysteine level in current smokers was significantly higher than that in never smokers (P = 0.004); while the serum folic acid and serum superoxide dismutase (SOD) level were significantly lower those in never smokers (P = 0.012; P = 0.004). The daily smoking consumption and the pack-years of smoking were significantly positively correlated with total homocysteine (tHcy) level (P = 0.020; P = 0.003). The reduced serum SOD level might be associated with increased risk of hypertension (P = 0.023), coronary heart disease (P = 0.018), and stroke (P = 0.035). However, the elevated serum tHcy level was not correlated with increased risk of hypertension and coronary heart disease, while may increase the risk of ischemic stroke (P = 0.075). Conclusions: Smoking status is still prevalent among Chinese elderly patients with cardiovascular diseases, which causes the increase of serum tHcy and the decrease of serum folate as well as SOD; smoking consumption per day and pack-years of smoking have indirect effects on tHcy. And decrease of serum SOD is a risk factor for cardiovascular diseases, increase of serum tHcy may be associated with changes of metabolism caused by oxidative damage.",
        "keywords": [
            "Cardiovascular disease",
            "Cigarette smoking",
            "Homocysteine",
            "Superoxide dismutase"
        ],
        "venue": "International Journal of Clinical and Experimental Medicine",
        "year": 2015,
        "id": "NayxFxMp"
    },
    "rXgTYiHs": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Department of Cardiology, Tongji Hospital of Tongji University"
            },
            {
                "name": "Yu Mao",
                "org": "Department of Cardiology, Tongji Hospital of Tongji University"
            },
            {
                "name": "Lemin Wang",
                "org": "Department of Cardiology, Tongji Hospital of Tongji University"
            },
            {
                "name": "Jinfa Jiang",
                "org": "Department of Cardiology, Tongji Hospital of Tongji University"
            },
            {
                "name": "Wenjun Xu",
                "org": "Department of Cardiology, Tongji Hospital of Tongji University"
            },
            {
                "name": "Jiahong Xu",
                "org": "Department of Cardiology, Tongji Hospital of Tongji University"
            },
            {
                "name": "Haoming Song",
                "org": "Department of Cardiology, Tongji Hospital of Tongji University"
            }
        ],
        "title": "Comparison of peripheral blood T lymphocyte immune function among venous thromboembolism patients with and without infection and patients with simple infection",
        "abstract": "Objective: To investigate the differences of T lymphocyte subgroups and high-sensitivity C reactive protein (HsCRP) levels among patients with venous thromboembolism (VTE), VTE patients with infection, simple infection patients and the normal controls. Method: 289 patients were enrolled in this study and divided into control group, VTE group, VTE with infection group and simple infection group. Result: Compared with the control group, the serum levels of CD3<sup>+</sup>, CD4<sup>+</sup>, CD8<sup>+</sup>T lymphocytes significantly decreased and CD4<sup>+</sup>/CD8<sup>+</sup>ratio significantly increased in simple infection group (P < 0.05); CD3<sup>+</sup>and CD8<sup>+</sup>T lymphocytes significantly decreased and CD4<sup>+</sup>/CD8<sup>+</sup>ratio significantly increased in VTE and VTE with infection group (P < 0.05); the proportion of declined CD3<sup>+</sup>and CD8<sup>+</sup>T lymphocytes increased, and the proportion of increased CD4<sup>+</sup>/CD8<sup>+</sup>ratio statistically elevated in three disease groups. As an important inflammatory factor, all HsCRP levels in three disease groups significantly increased when compared with the control group. Conclusion: Immune dysfunction exists in both of VTE and infection patients, while VTE patients tend to be accompanied with infections. The changes of T lymphocyte subgroups in VTE patients, who were independent from infection, could cause T lymphocyte immune dysfunction, suggesting that there were abnormalities of T lymphocyte immune function in VTE itself. The overall T lymphocyte functions of recognizing antigens and transducing activation signals decline in VTE patients. Besides, the function of T lymphocyte of directly killing virus microbes declines significantly and the inflammatory mechanisms are involved in the occurrence and development of venous thrombosis.",
        "keywords": [
            "Immune function",
            "T lymphocyte",
            "Venous thromboembolism"
        ],
        "venue": "International Journal of Clinical and Experimental Medicine",
        "year": 2015,
        "id": "rXgTYiHs"
    },
    "JJEB9qGD": {
        "authors": [
            {
                "name": "Wenwen Yan",
                "org": ""
            },
            {
                "name": "Lemin Wang",
                "org": ""
            },
            {
                "name": "Jinfa Jiang",
                "org": ""
            },
            {
                "name": "Wenjun Xu",
                "org": ""
            },
            {
                "name": "Zhu Gong",
                "org": ""
            },
            {
                "name": "Qianglin Duan",
                "org": ""
            },
            {
                "name": "Chuanrong Li",
                "org": ""
            },
            {
                "name": "Haoming Song",
                "org": ""
            },
            {
                "name": "Lin Che",
                "org": ""
            },
            {
                "name": "Yuqin Shen",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            }
        ],
        "title": "Differential expression of T cell-related genes in AMI and SA stages of coronary artery disease",
        "abstract": "Objective: To identify differentially expressed T cells-related genes in peripheral blood mononuclear cells and compare their differences in T cell activation and subset functions in different stages of coronary atherosclerosis disease (CAD). Methods: 20 patients with acute myocardial infarction patients (AMI), 20 patients with stable angina pectoris (SA) and 20 healthy volunteers were recruited into the study. Whole human genome microarray analysis was used to detect the expression of T cell related genes among three groups. Results: mRNA expression of 68 genes involved in T cell was detected. 1) Antigen recognition: in the AMI patients 12 genes were down-regulated and 9 were significantly down-regulated among all 13 genes, compared with those of the SA and the control group, respectively. 2) Co-stimulators and regulators of T cell activation: among 16 genes in the AMI patients, 15 genes were lower and 8 were significantly lower than the other two groups. 3) T cell subsets, CTL: all 11 genes in the AMI patients were down-regulated, particularly GZMM and CASP8 were significantly down-regulated compared with the SA patients and controls. Th1/Th2: in the AMI patients, gene expressions including IL1 and IL18 were significantly higher, whereas GATA3 mRNA was significantly lower than those in other two groups. Th17/Treg: in the AMI group, RORC and CCR6 mRNAs were significantly down-regulated compared with the control group, while CD25 and CD127 expressions were significantly lower than SA group. There was no difference in T cell related genes between the SA patients and the controls. Conclusions: In the AMI patients, the mRNA expression of T cell antigen recognition, activation and subset functions was imbalanced or decreased, indicating the dysfunction of cellular immunity in patients with AMI. Then improving T cell mediated cellular immunity may be considered as a potential target for medical interventions in the patients with AMI.",
        "keywords": [
            "Cellular immunity",
            "Gene expression",
            "Myocardial infarction",
            "Stable angina pectoris",
            "T cell"
        ],
        "venue": "International Journal of Clinical and Experimental Medicine",
        "year": 2015,
        "id": "JJEB9qGD"
    },
    "nNvAy76t": {
        "authors": [
            {
                "name": "Yong Ma",
                "org": "Department of Urology, Zhongshan Hospital, Fudan University"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Urology, Zhongshan Hospital, Fudan University"
            },
            {
                "name": "Jian-Ming Guo",
                "org": "Department of Urology, Zhongshan Hospital, Fudan University"
            },
            {
                "name": "Guo-Min Wang",
                "org": "Department of Urology, Zhongshan Hospital, Fudan University"
            },
            {
                "name": "Juan Liu",
                "org": "Department of Nephrology, Medical Center of Boston University"
            },
            {
                "name": "Wei-Ning Lu",
                "org": "Department of Nephrology, Medical Center of Boston University"
            },
            {
                "name": "Hang Wang",
                "org": "Department of Urology, Zhongshan Hospital, Fudan University"
            }
        ],
        "title": "Noninvasively detection for newborn mouse suffered congenital hydronephrosis by using ultrasound biomicroscopy",
        "keywords": [
            "Congenital disease",
            "Hydronepheosis",
            "Newborn mice",
            "Ultrasound biomicroscopy"
        ],
        "venue": "Fudan University Journal of Medical Sciences",
        "year": 2014,
        "id": "nNvAy76t"
    },
    "flCl90Dl": {
        "authors": [
            {
                "name": "Hang Wang",
                "org": "Department of Urology, Zhongshan Hospital, Fudan University"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Urology, Zhongshan Hospital, Fudan University"
            },
            {
                "name": "Jianming Guo",
                "org": "Department of Urology, Zhongshan Hospital, Fudan University"
            },
            {
                "name": "Li'an Sun",
                "org": "Department of Urology, Zhongshan Hospital, Fudan University"
            },
            {
                "name": "Qilai Long",
                "org": "Department of Urology, Zhongshan Hospital, Fudan University"
            },
            {
                "name": "Yong Ma",
                "org": "Department of Urology, Zhongshan Hospital, Fudan University"
            },
            {
                "name": "Li Zhang",
                "org": "Department of Urology, Zhongshan Hospital, Fudan University"
            },
            {
                "name": "Zongming Lin",
                "org": "Department of Urology, Zhongshan Hospital, Fudan University"
            },
            {
                "name": "Tongyu Zhu",
                "org": "Department of Urology, Zhongshan Hospital, Fudan University"
            },
            {
                "name": "Guomin Wang",
                "org": "Department of Urology, Zhongshan Hospital, Fudan University"
            }
        ],
        "title": "Mini-flank supra-12th rib incision for open partial nephrectomy compared with laparoscopic partial nephrectomy and traditional open partial nephrectomy",
        "abstract": "Purpose: The purpose of this study was to report our approach of partial nephrectomy (PN) using a supra-12th rib mini-flank incision. We compared mini-incision open partial nephrectomy (MI-OPN) with open partial nephrectomy (OPN) and laparoscopic partial nephrectomy (LPN) to verify whether MI-OPN can be an alternative to OPN and LPN. Methods: This was a retrospective single-center study including 194 patients who underwent partial nephrectomy (PN) between February 2005 and December 2010. Demographic, perioperative, and complication data were compared among the MI-OPN group, OPN group and LPN group. Results: No statistical differences were reported in either group for age, sex, BMI, tumour side (right or left kidney), RENAL nephrometry scores, PADUA score and preoperative eGFR. The operative time was longer in LPN group when compared with MI-OPN and OPN group (all P<0.001). The warm ischemia time of LPN group was longer than MI-OPN group (P = 0.032) and OPN group (P = 0.005). The length of stay of LPN group was shorter than OPN group (P = 0.018), but was similar to MIOPN group (P = 0.094). The incidence of renal artery clamping was lower in OPN group when compared with MI-OPN and LPN group (all P<0.001). More estimated blood loss was found in OPN group when compared with MI-OPN group (p = 0.003) and LPN group (P = 0.014). The overall incidence of postoperative complications was similar. Conclusions: The approach of MI-OPN can couple the benefits of both minimally invasive and open partial nephrectomy techniques with less estimated blood loss, shorter operative time, shorter length of stay, less postoperative complications, and a smaller incision. MI-OPN may be an effective alternative to laparoscopic or traditional open approaches, which maybe more suitable for the tumors with high RENAL nephrometry score or PADUA score. \u00a9 2014 Wang et al.",
        "keywords": [
            ""
        ],
        "venue": "PLoS ONE",
        "year": 2014,
        "id": "flCl90Dl"
    },
    "SEUZr36h": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Department of Urology, Zhongshan Hospital, Fudan University"
            },
            {
                "name": "Jianming Guo",
                "org": "Department of Urology, Zhongshan Hospital, Fudan University"
            },
            {
                "name": "Hang Wang",
                "org": "Department of Urology, Zhongshan Hospital, Fudan University"
            },
            {
                "name": "Guomin Wang",
                "org": "Department of Urology, Zhongshan Hospital, Fudan University"
            }
        ],
        "title": "The Zhongshan score: A novel and simple anatomic classification system to predict perioperative outcomes of nephron-sparing surgery",
        "abstract": "ABSTRACT: In the zero ischemia era of nephron-sparing surgery (NSS), a new anatomic classification system (ACS) is needed to adjust to these new surgical techniques. We devised a novel and simple ACS, and compared it with the RENAL and PADUA scores to predict the risk of NSS outcomes.We retrospectively evaluated 789 patients who underwent NSS with available imaging between January 2007 and July 2014. Demographic and clinical data were assessed. The Zhongshan (ZS) score consisted of three parameters.RENAL, PADUA, and ZS scores are divided into three groups, that is, high, moderate, and low scores. For operative time (OT), significant differences were seen between any two groups of ZS score and PADUA score (all P<0.05). For ZS score, patients with moderate and high scores had longer warm ischemia time (WIT) and greater increase in SCr compared with low score (all Pa<0.05). What is more, the differences between moderate and high scores classified by ZS score were borderline but trending toward significance in WIT (P=0.064) and increase in SCr (P=0.052). Interestingly, RENAL showed no significant difference between moderate and high complexity in OT, WIT, estimated blood loss, and increase in SCr. Compared with patients with a low score of ZS, those with a high or moderate score had 8.1-fold or 3.3-fold higher risk of surgical complications, respectively (all P<0.05). As for RENAL score, patients with a high or moderate score had 5.7-fold or 1.9-fold higher risk of surgical complications, respectively (all P<0.05). Patients with a high or moderate score of PADUA had 2.3-fold or 2.8-fold higher risk of surgical complications, respectively (all P<0.05). In the ROC curve analysis, ZS score had the greatest AUC for surgical complications (AUC=0.632) and the conversion to radical nephrectomy (AUC=0.845) (all P<0.05).In conclusion, the ability of ZS score to predict the surgical complexity and surgical complications of NSS is better than RENAL and PADUA scores. ZS score could be used to reflect the surgical complexity and predict the risk of surgical complications in patients undergoing NSS.",
        "keywords": [
            ""
        ],
        "venue": "Medicine (United States)",
        "year": 2015,
        "id": "SEUZr36h"
    },
    "iyM9IsTN": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Department of Urology, Zhongshan Hospital, Fudan University"
            },
            {
                "name": "Yingli Cao",
                "org": "Department of Radiology, Zhongshan Hospital, Fudan University"
            },
            {
                "name": "Tingchang Bian",
                "org": "Department of Urology, Zhongshan Hospital, Fudan University"
            },
            {
                "name": "Zhuoyi Xiang",
                "org": "Department of Urology, Zhongshan Hospital, Fudan University"
            },
            {
                "name": "Yaohui Li",
                "org": "Department of Urology, Zhongshan Hospital, Fudan University"
            },
            {
                "name": "Jianming Guo",
                "org": "Department of Urology, Zhongshan Hospital, Fudan University"
            },
            {
                "name": "Zongming Lin",
                "org": "Department of Urology, Zhongshan Hospital, Fudan University"
            },
            {
                "name": "Guomin Wang",
                "org": "Department of Urology, Zhongshan Hospital, Fudan University"
            },
            {
                "name": "Hang Wang",
                "org": "Department of Urology, Zhongshan Hospital, Fudan University"
            }
        ],
        "title": "Number of Renal Columns Invaded by Tumor: A Novel Parameter for Predicting Complexity and Outcomes of Off-Clamp Open Partial Nephrectomy",
        "abstract": "Background The number of renal columns invaded by tumor (NRC) can determine the tumor complexity and perioperative outcomes of off-clamp open partial nephrectomy (OPN). We aimed to propose a novel and simple scoring system and examine the relationship between NRC and perioperative outcomes after off-clamp OPN. Study Design We retrospectively evaluated 202 patients with contrast-enhanced CT imaging who underwent off-clamp OPN between January 2008 and November 2014. The number of renal columns invaded by tumor was correlated to baseline demographics and perioperative outcomes as a categorical variable using multivariable logistic regression analysis. Results The mean tumor size was 2.5 cm (\u00b11.3 cm). The number of renal columns invaded by tumor had the highest correlation coefficients with estimated blood loss (coefficient = 0.485; p < 0.001), operative time (coefficient = 0.310; p < 0.001), postoperative drainage (coefficient = 0.307; p < 0.001), and hospital length of stay (coefficient = 0.144; p = 0.041). Multivariable logistic regression demonstrated NRC to be an independent predictor of estimated blood loss \u2265500 mL, postoperative renal function, operative time, and surgical complications. This predictive ability of NRC was superior to the R.E.N.A.L. (radius exophyic/endophytic nearness anterior/posterior location) score and PADUA (preoperative aspects and dimensions used for an anatomical) score. Spearman correlation coefficient of NRC calculations between the 2 observers was 0.941 (p < 0.001). Conclusions The number of renal columns invaded by tumor is a novel, intuitive, and practical parameter that could be used to quantify renal tumor complexity and predict the risk of perioperative outcomes after off-clamp OPN. Specifically, NRC correlates with estimated blood loss, operative time, surgical complications, renal function, and conversion to on-clamp. In the future, NRC can be integrated with other parameters, such as tumor location, to assemble a new scoring system.",
        "keywords": [
            ""
        ],
        "venue": "Journal of the American College of Surgeons",
        "year": 2015,
        "id": "iyM9IsTN"
    },
    "tRmwGGpw": {
        "authors": [
            {
                "name": "Hang Wang",
                "org": "Department of Urology, Zhongshan Hospital, Fudan University"
            },
            {
                "name": "Li-An Sun",
                "org": "Department of Urology, Zhongshan Hospital, Fudan University"
            },
            {
                "name": "Yiwei Wang",
                "org": "Department of Urology, Zhongshan Hospital, Fudan University"
            },
            {
                "name": "Zhuoyi Xiang",
                "org": "Department of Urology, Zhongshan Hospital, Fudan University"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Urology, Zhongshan Hospital, Fudan University"
            },
            {
                "name": "Jianming Guo",
                "org": "Department of Urology, Zhongshan Hospital, Fudan University"
            },
            {
                "name": "Guomin Wang",
                "org": "Department of Urology, Zhongshan Hospital, Fudan University"
            }
        ],
        "title": "Mini-flank supra-12th rib incision for open partial nephrectomy for renal tumor with RENAL nephrometry score\u226510",
        "abstract": "The skill of supra-12th rib mini-flank approach for open partial nephrectomy (MI-OPN) provides an advanced operative method for renal tumor. Compared with laparoscopic and robotic surgery, it may be a feasible selection for the complex renal tumors. We describe our techniques and results of MI-OPN in complex renal tumors with high RENAL nephrometry score (RENAL nephrometry score\u226510). Fifty-five patients diagnosed with renal tumors between January 2009 and July 2013 were included in this study. Eligibility criteria comprised of patients with complex renal tumor (RENAL score\u226510) being candidates for partial nephrectomy (PN). All patients received MI-OPN and all surgeries were performed by a single urologist. The preoperative workup comprised of medical history, physical examination, and routine laboratory tests. Serum creatinine was recorded preoperatively and 2 to 3 months after operation. Operative time, ischemia time, blood loss, operative and postoperative complications, renal function, and pathology parameters were recorded. MI-OPN was successfully performed in all cases. Mean tumor size was 4.7cm (range: 2.5-8.1). Mean warm ischemia time was 28.1 minutes (range: 21-39), mean operative time was 105minutes (range: 70-150) and mean estimated blood loss was 68mL (range: 10-400). Mean postoperative hospital stay was 6.5 days (range: 5-12). Postoperative complications were found in 3 patients (5.5%). The mean pre-and postoperative serum creatinine levels were 76.2\u03bcmol/L (range: 47-132) and 87.1\u03bcmol/L (range: 61-189) with significant difference (P=0.004). The mean pre-and postoperative estimated glomerular filtration rate (eGFR) were 91.5 (range: 34-133) and 82.5 (range: 22-126.5), respectively with significant difference (P=0.024). In an average follow-up of 19.9 months (range: 8-50), no local recurrence or systemic progression occurred. In conclusion, MI-OPN can combine the benefits of both minimal invasive and traditional open partial nephrectomy (OPN) techniques with a smaller incision. It is an innovation of traditional OPN and suitable for the complex renal tumors with high RENAL nephrometry score safely and effectively.",
        "keywords": [
            ""
        ],
        "venue": "Medicine (United States)",
        "year": 2015,
        "id": "tRmwGGpw"
    },
    "izo2RhI6": {
        "authors": [
            {
                "name": "Yuan Chang",
                "org": "Department of Urology, Zhongshan Hospital, Fudan University"
            },
            {
                "name": "Qiang Fu",
                "org": "Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University"
            },
            {
                "name": "Le Xu",
                "org": "Department of Urology, Ruijin Hospital, School of Medicine, Shanghai Jiaotong University"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Urology, Zhongshan Hospital, Fudan University"
            },
            {
                "name": "Zheng Liu",
                "org": "Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University"
            },
            {
                "name": "Yuanfeng Yang",
                "org": "Department of Urology, Zhongshan Hospital, Fudan University"
            },
            {
                "name": "Zongming Lin",
                "org": "Department of Urology, Zhongshan Hospital, Fudan University"
            },
            {
                "name": "Jiejie Xu",
                "org": "Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University"
            }
        ],
        "title": "Prognostic value of preoperative lymphocyte to monocyte ratio in patients with nonmetastatic clear cell renal cell carcinoma",
        "abstract": "Growing evidence indicates that systemic inflammation involves in cancer development and progression. Preoperative lymphocyte to monocyte ratio (LMR) has been estimated as an independent prognostic factor of various cancers. We investigated the prognostic value of LMR in nonmetastatic clear cell renal cell carcinoma (ccRCC) patients after surgery. We retrospectively recruited 430 consecutive patients with nonmetastatic ccRCC (T1-3N0M0) who underwent curative nephrectomy between 2008 and 2009 at a single center in China. Lymphocyte and monocyte counts were obtained at hospitalization before surgery. Preoperative LMR as a continuous variable and as a dichotomized variable at a level of 3.25, which was the 25th percentile value, were analyzed in unvariable and multivariable Cox regression models, respectively. Concordance index (C-index) was calculated to assess predictive accuracy. Kaplan-Meier method was applied to compare survival curves. As both of the continuous and dichotomized variable, decreased preoperative LMR was proven to be independent prognostic factors of recurrence-free survival (P = 0.039 and P = 0.003, respectively) and overall survival (P = 0.002 and P < 0.001, respectively). Further examination revealed that the dichotomized LMR could enhance the predictive accuracy of each of the existing prognostic models among intermediate-risk to high-risk patients. The preoperative LMR is an independent prognostic factor of recurrence-free survival and overall survival for nonmetastatic ccRCC patients after surgery, and it can be used in tandem with established prognostic systems to further enhance outcome prediction in intermediate-risk to high-risk patients.",
        "keywords": [
            "Biomarker",
            "Inflammation",
            "Overall survival",
            "Recurrence-free survival",
            "Renal cell carcinoma"
        ],
        "venue": "Tumor Biology",
        "year": 2015,
        "id": "izo2RhI6"
    },
    "GnEVxCYn": {
        "authors": [
            {
                "name": "Wencui Peng",
                "org": "University of Chinese Academy of Sciences"
            },
            {
                "name": "Lin Zhou",
                "org": "Center for Cold Atom Physics, Chinese Academy of Sciences"
            },
            {
                "name": "Shitong Long",
                "org": "University of Chinese Academy of Sciences"
            },
            {
                "name": "Jin Wang",
                "org": "Center for Cold Atom Physics, Chinese Academy of Sciences"
            },
            {
                "name": "Mingsheng Zhan",
                "org": "Center for Cold Atom Physics, Chinese Academy of Sciences"
            }
        ],
        "title": "Locking laser frequency of up to 40 GHz offset to a reference with a 10 GHz electro-optic modulator",
        "abstract": "We demonstrate a method to lock a laser frequency of up to 40 GHz offset to a reference using a 10 GHz waveguidetype electro-optic modulator (EOM). Offsetting is provided by the EOM sidebands, and first- to fourth-order sidebands are generated by changing the power of the EOM's driving radio frequency. By scanning the driving frequency across the 10 GHz bandwidth, the output laser frequency can be set at any point in an 80 GHz range (from ?40 to 40 GHz) by locking a sideband to the reference. This method provides simple, stable, and low-cost generation of phase-coherent laser pairs separated by tens of GHz. \u00a9 2014 Optical Society of America.",
        "keywords": [
            ""
        ],
        "venue": "Optics Letters",
        "year": 2014,
        "id": "GnEVxCYn"
    },
    "k8ESzg5O": {
        "authors": [
            {
                "name": "Wei Yang",
                "org": "University of Chinese Academy of Sciences"
            },
            {
                "name": "Da-Li Sun",
                "org": "University of Chinese Academy of Sciences"
            },
            {
                "name": "Lin Zhou",
                "org": "Center for Cold Atom Physics, Chinese Academy of Sciences"
            },
            {
                "name": "Jin Wang",
                "org": "Center for Cold Atom Physics, Chinese Academy of Sciences"
            },
            {
                "name": "Ming-Sheng Zhan",
                "org": "Center for Cold Atom Physics, Chinese Academy of Sciences"
            }
        ],
        "title": "Zeeman slowing and magneto-optically trapping of lithium atoms in atomic interferometry experiments",
        "abstract": "To prepare cold lithium atoms for atomic interferometry experiments, we have carried out experimental researches on Zeeman deceleration and magneto-optical trap (MOT) of lithium atoms. We have also designed and implemented a compact adjustable Zeeman slower with an inner water cooling chamber, to decelerate the velocity of the ",
        "keywords": [
            "Atom interferometer",
            "Laser cooling and trapping",
            "Magneto-optical trap",
            "Zeeman slower"
        ],
        "venue": "Wuli Xuebao/Acta Physica Sinica",
        "year": 2014,
        "id": "k8ESzg5O"
    },
    "2NDQqbT9": {
        "authors": [
            {
                "name": "Biao Tang",
                "org": "University of Chinese Academy of Sciences"
            },
            {
                "name": "Lin Zhou",
                "org": "Center for Cold Atom Physics, Chinese Academy of Sciences"
            },
            {
                "name": "Zongyuan Xiong",
                "org": "Center for Cold Atom Physics, Chinese Academy of Sciences"
            },
            {
                "name": "Jin Wang",
                "org": "Center for Cold Atom Physics, Chinese Academy of Sciences"
            },
            {
                "name": "Mingsheng Zhan",
                "org": "Center for Cold Atom Physics, Chinese Academy of Sciences"
            }
        ],
        "title": "A programmable broadband low frequency active vibration isolation system for atom interferometry",
        "abstract": "Vibration isolation at low frequency is important for some precision measurement experiments that use atom interferometry. To decrease the vibrational noise caused by the reflecting mirror of Raman beams in atom interferometry, we designed and demonstrated a compact stable active low frequency vibration isolation system. In this system, a digital control subsystem is used to process and feedback the vibration measured by a seismometer. A voice coil actuator is used to control and cancel the motion of a commercial passive vibration isolation platform. With the help of field programmable gate array-based control subsystem, the vibration isolation system performed flexibly and accurately. When the feedback is on, the intrinsic resonance frequency of the system will change from 0.8 Hz to about 0.015 Hz. The vertical vibration (0.01-10 Hz) measured by the in-loop seismometer is reduced by an additional factor of up to 500 on the basis of a passive vibration isolation platform, and we have proved the performance by adding an additional seismometer as well as applying it in the atom interferometry experiment.",
        "keywords": [
            ""
        ],
        "venue": "Review of Scientific Instruments",
        "year": 2014,
        "id": "2NDQqbT9"
    },
    "zcc9np09": {
        "authors": [
            {
                "name": "Wei Yang",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Shitong Long",
                "org": ""
            },
            {
                "name": "Wencui Peng",
                "org": ""
            },
            {
                "name": "Jin Wang",
                "org": ""
            },
            {
                "name": "Mingsheng Zhan",
                "org": ""
            }
        ],
        "title": "Time-division-multiplexing laser seededamplification in a tapered amplifier",
        "abstract": "We demonstrate time-division-multiplexing (TDM) laser seeded optical amplification in a diode laser amplifier. With an acousto-optic modulator we combine two seeding beams of different frequencies and inject them alternately in the time domain into the tapered amplifier (TA) chip at a switching speed of 200 ns. The output high-power dual frequency components from the TA are time separated. The TDM seeded TA works safely and efficiently, which is useful for compact precision measurement instruments such as optical clocks and atom interferometers.",
        "keywords": [
            ""
        ],
        "venue": "Chinese Optics Letters",
        "year": 2015,
        "id": "zcc9np09"
    },
    "nhDC5wei": {
        "authors": [
            {
                "name": "Biao Tang",
                "org": ""
            },
            {
                "name": "Bao-Cheng Zhang",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Jin Wang",
                "org": ""
            },
            {
                "name": "Ming-Sheng Zhan",
                "org": ""
            }
        ],
        "title": "Sensitivity function analysis of gravitational wave detection with single-laser and large-momentum-transfer atomic sensors",
        "abstract": "Recently, a configuration using atomic interferometers (AIs) had been suggested for the detection of gravitational waves. A new AI with some additional laser pulses for implementing large momentum transfer was also put forward, in order to reduce the effect of shot noise and laser frequency noise. We use a sensitivity function to analyze all possible configurations of the new AI and to distinguish how many momenta are transferred in a specific configuration. By analyzing the new configuration, we further explore a detection scheme for gravitational waves, in particular, that ameliorates laser frequency noise. We find that the amelioration occurs in such a scheme, but novelly, in some cases, the frequency noise can be canceled completely by using a proper data processing method.",
        "keywords": [
            "Atomic interferometer",
            "Gravitational wave detection",
            "Laser frequency noise"
        ],
        "venue": "Research in Astronomy and Astrophysics",
        "year": 2015,
        "id": "nhDC5wei"
    },
    "pGn4jRSX": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Center for Cold Atom Physics, Chinese Academy of Sciences"
            },
            {
                "name": "Shitong Long",
                "org": "University of Chinese Academy of Sciences"
            },
            {
                "name": "Biao Tang",
                "org": "Center for Cold Atom Physics, Chinese Academy of Sciences"
            },
            {
                "name": "Xi Chen",
                "org": "Center for Cold Atom Physics, Chinese Academy of Sciences"
            },
            {
                "name": "Fen Gao",
                "org": "Center for Cold Atom Physics, Chinese Academy of Sciences"
            },
            {
                "name": "Wencui Peng",
                "org": "Center for Cold Atom Physics, Chinese Academy of Sciences"
            },
            {
                "name": "Weitao Duan",
                "org": "University of Chinese Academy of Sciences"
            },
            {
                "name": "Jiaqi Zhong",
                "org": "Center for Cold Atom Physics, Chinese Academy of Sciences"
            },
            {
                "name": "Zongyuan Xiong",
                "org": "Center for Cold Atom Physics, Chinese Academy of Sciences"
            },
            {
                "name": "Jin Wang",
                "org": "Center for Cold Atom Physics, Chinese Academy of Sciences"
            },
            {
                "name": "Yuanzhong Zhang",
                "org": "Institute of Theoretical Physics, Chinese Academy of Sciences"
            },
            {
                "name": "Mingsheng Zhan",
                "org": "Center for Cold Atom Physics, Chinese Academy of Sciences"
            }
        ],
        "title": "Test of Equivalence Principle at 10-8 Level by a Dual-Species Double-Diffraction Raman Atom Interferometer",
        "keywords": [
            ""
        ],
        "venue": "Physical Review Letters",
        "year": 2015,
        "id": "pGn4jRSX"
    },
    "IFi13NXO": {
        "authors": [
            {
                "name": "Biao Tang",
                "org": "State Key Laboratory of Magnetic Resonances and Atomic and Molecular Physics, Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences"
            },
            {
                "name": "Baocheng Zhang",
                "org": "School of Mathematics and Physics, China University of Geosciences"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Magnetic Resonances and Atomic and Molecular Physics, Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences"
            },
            {
                "name": "Jin Wang",
                "org": "State Key Laboratory of Magnetic Resonances and Atomic and Molecular Physics, Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences"
            },
            {
                "name": "Mingsheng Zhan",
                "org": "State Key Laboratory of Magnetic Resonances and Atomic and Molecular Physics, Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences"
            }
        ],
        "title": "Influence of separating distance between atomic sensors for gravitational wave detection",
        "abstract": "We consider a recent scheme of gravitational wave detection using atomic interferometers as inertial sensors, and reinvestigate its configuration using the concept of sensitivity functions. We show that such configuration can suppress noise without influencing the gravitational wave signal. But the suppression is insufficient for the direct observation of gravitational wave signals, so we analyse the behaviour of the different noises influencing the detection scheme. As a novel method, we study the relations between the measurement sensitivity and the distance between two interferometers, and find that the results derived from vibration noise and laser frequency noise are in stark contrast to that derived from the shot noise, which is significant for the configuration design of gravitational wave detectors using atomic interferometers. Graphical abstract: [Figure not available: see fulltext.]",
        "keywords": [
            "Atomic Physics"
        ],
        "venue": "European Physical Journal D",
        "year": 2015,
        "id": "IFi13NXO"
    },
    "TbcBwr2s": {
        "authors": [
            {
                "name": "Tao Chen",
                "org": ""
            },
            {
                "name": "Liang Chen",
                "org": ""
            },
            {
                "name": "Haicheng Li",
                "org": ""
            },
            {
                "name": "Yuhui Chen",
                "org": ""
            },
            {
                "name": "Huixin Guo",
                "org": ""
            },
            {
                "name": "Yang Shu",
                "org": ""
            },
            {
                "name": "Zhiyu Chen",
                "org": ""
            },
            {
                "name": "Changhui Cai",
                "org": ""
            },
            {
                "name": "Lina Guo",
                "org": ""
            },
            {
                "name": "Xianen Zhang",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Qiu Zhong",
                "org": ""
            }
        ],
        "title": "Design and in vitro evaluation of a novel poly(methacrylic acid)/metronidazole antibacterial nanogel as an oral dosage form",
        "abstract": "To overcome the undesirable side-effects of metronidazole (MTZ), ethylene glycol dimethacrylate is used as the cross-linker, and a series of poly(methacrylic acid) (PMAA) nanogels were prepared to load the MTZ. We investigated the morphology, size, in vitro release property in the simulated gastrointestinal medium, long-term antibacterial performance against Bacteroides fragilis, cytotoxicity, stability and activity of this novel MTZ/PMAA nanogel. The results indicate that the MTZ/PMAA nanogel sustained the release of MTZ in long-term antibacterial activity in the simulated gastrointestinal medium. This MTZ/PMAA nanogel exhibits less cytotoxicity than MTZ alone, suggesting that MTZ/PMAA nanogel is a more useful dosage form than MTZ for mild-to-moderate Clostridium difficile infections. The novel aspects of this study include the synthesis of a nanogel and the three-phase study of the release profile, which might be useful for other researchers in this field. \u00a9 2014 .",
        "keywords": [
            "Cytotoxicity",
            "Long-term activity",
            "Metronidazole",
            "Nanogel",
            "Poly(methacrylic acid)",
            "Sustained release"
        ],
        "venue": "Colloids and Surfaces B: Biointerfaces",
        "year": 2014,
        "id": "TbcBwr2s"
    },
    "X8SiXYty": {
        "authors": [
            {
                "name": "Tao Liu",
                "org": ""
            },
            {
                "name": "Hongxi Liu",
                "org": ""
            },
            {
                "name": "Zhimin Wu",
                "org": ""
            },
            {
                "name": "Tao Chen",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Yuanyuan Liang",
                "org": ""
            },
            {
                "name": "Bo Ke",
                "org": ""
            },
            {
                "name": "Hongxing Huang",
                "org": ""
            },
            {
                "name": "Zhenyou Jiang",
                "org": ""
            },
            {
                "name": "Mingqiang Xie",
                "org": ""
            },
            {
                "name": "Ting Wu",
                "org": ""
            }
        ],
        "title": "The use of poly(methacrylic acid) nanogel to control the release of amoxycillin with lower cytotoxicity",
        "abstract": "In order to control the release of amoxycillin (AM) with lower cytotoxicity and higher activity, ethylene glycol dimethacrylate was used as the cross-linker, and a series of poly(methacrylic acid) (PMAA) nanogels were prepared to load the AM. Then, the morphology, size, in vitro release property, long-term antibacterial performance, cytotoxicity, stability and activity of this novel AM/PMAA nanogel were investigated. The results showed that the AM/PMAA nanogel sustainably released AM with long-term antibacterial activity. Moreover, the AM/PMAA nanogel could improve the stability of AM. More importantly, this AM/PMAA nanogel showed slighter cytotoxicity than AM alone, suggesting that the AM/PMAA nanogel was a more useful dosage form than AM for infectious diseases. \u00a9 2014 Elsevier B.V. All rights reserved.",
        "keywords": [
            "Amoxicillin",
            "Cytotoxicity",
            "Long-term activity",
            "Nanogel",
            "Poly(methacrylic acid)",
            "Sustained release"
        ],
        "venue": "Materials Science and Engineering C",
        "year": 2014,
        "id": "X8SiXYty"
    },
    "Uixf93QH": {
        "authors": [
            {
                "name": "Wei Wang",
                "org": "Department of Clinical Laboratory and Disease Control"
            },
            {
                "name": "Tao Chen",
                "org": "Department of Provincial Reference Laboratory and Disease Control"
            },
            {
                "name": "Haicheng Li",
                "org": "Department of Provincial Reference Laboratory and Disease Control"
            },
            {
                "name": "Yuhui Chen",
                "org": "Department of Provincial Reference Laboratory and Disease Control"
            },
            {
                "name": "Zhilong Wu",
                "org": "Department of Clinical Laboratory and Disease Control"
            },
            {
                "name": "Tongming Feng",
                "org": "Department of Clinical Laboratory and Disease Control"
            },
            {
                "name": "Xilin Zhang",
                "org": "Department of Clinical Laboratory and Disease Control"
            },
            {
                "name": "Qiu Zhong",
                "org": "Department of Provincial Reference Laboratory and Disease Control"
            },
            {
                "name": "Qianhong Zhong",
                "org": "Department of Clinical Laboratory and Disease Control"
            },
            {
                "name": "Guozhou Li",
                "org": "Department of Clinical Laboratory"
            },
            {
                "name": "Lina Guo",
                "org": "Department of Nutrition"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Provincial Reference Laboratory and Disease Control"
            },
            {
                "name": "Jie Zhou",
                "org": "Department of Clinical Laboratory and Disease Control"
            }
        ],
        "title": "Screening a novel FGF3 antagonist peptide with anti-tumor effects on breast cancer from a phage display library",
        "abstract": "Accumulating evidence has suggested that fibroblast growth factor 3 (FGF3) is expressed in breast cancer and correlates with the stage and grade of the disease. In the present study, a specific FGF3-binding peptide (VLWLKNR, termed FP16) was isolated from a phage display heptapeptide library with FGF3. The peptide FP16 contained four identical (WLKN) amino acids and demonstrated high homology to the peptides of the 188-194 (TMRWLKN) site of the high-affinity FGF3 receptor fibroblast growth factor receptor 2. Functional analyses indicated that FP16 mediated significant inhibition of FGF3-induced cell proliferation, arrested the cell cycle at the G0/G1 phase by increasing proliferation-associated protein 2G4, suppressing cyclin D1 and proliferating cell nuclear antigen, and inhibited the FGF3-induced activation of extracellular signal-regulated kinase 1/2 and Akt kinase. Taken together, these results demonstrated that the peptide FP16, acting as an FGF3 antagonist, is a promising therapeutic agent for the treatment of breast cancer.",
        "keywords": [
            "Breast cancer",
            "Cell cycle",
            "Fibroblast growth factor 3",
            "Phage display",
            "Proliferation"
        ],
        "venue": "Molecular Medicine Reports",
        "year": 2015,
        "id": "Uixf93QH"
    },
    "pUJWQxRI": {
        "authors": [
            {
                "name": "Tao Chen",
                "org": "Key Laboratory of Translational Medicine of Guangdong"
            },
            {
                "name": "Qiang Li",
                "org": "Department of General Surgery of the First Affiliated Hospital of Jinan University"
            },
            {
                "name": "Lina Guo",
                "org": "Guangdong Provincial Hospital of Chinese Medicine"
            },
            {
                "name": "Li Yu",
                "org": "Light Industry and Food Science, South China University of Technology"
            },
            {
                "name": "Zhenyan Li",
                "org": "Department of Microbiology and Immunology, Medical College of Jinan University"
            },
            {
                "name": "Huixin Guo",
                "org": "Key Laboratory of Translational Medicine of Guangdong"
            },
            {
                "name": "Haicheng Li",
                "org": "Key Laboratory of Translational Medicine of Guangdong"
            },
            {
                "name": "Meigui Zhao",
                "org": "Bao'an Chronic Diseases Prevention and Cure Hospital"
            },
            {
                "name": "Liang Chen",
                "org": "Key Laboratory of Translational Medicine of Guangdong"
            },
            {
                "name": "Xunxun Chen",
                "org": "Key Laboratory of Translational Medicine of Guangdong"
            },
            {
                "name": "Qiu Zhong",
                "org": "Key Laboratory of Translational Medicine of Guangdong"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Translational Medicine of Guangdong"
            },
            {
                "name": "Ting Wu",
                "org": "Department of Light Chemical Engineering, Guangdong Polytechnic"
            }
        ],
        "title": "Lower cytotoxicity, high stability, and long-term antibacterial activity of a poly(methacrylic acid)/isoniazid/rifampin nanogel against multidrug-resistant intestinal Mycobacterium tuberculosis",
        "abstract": "To overcome the undesirable side effects and reduce the cytotoxicity of isoniazid (INH) and rifampin (RMP) in the digestive tract, a poly(methacrylic acid) (PMAA) nanogel was developed as a carrier of INH and RMP. This PMAA/INH/RMP nanogel was prepared as a treatment for intestinal tuberculosis caused by multidrug-resistant Mycobacterium tuberculosis (MTB). The morphology, size, and in vitro release properties were evaluated in a simulated gastrointestinal medium, and long-term antibacterial performance, cytotoxicity, stability, and activity of this novel PMAA/INH/RMP nanogel against multidrug-resistant MTB in the intestine were investigated. Our results indicate that the PMAA/INH/RMP nanogel exhibited extended antibacterial activity by virtue of its long-term release of INH and RMP in the simulated gastrointestinal medium. Further, this PMAA/INH/RMP nanogel exhibited lower cytotoxicity than did INH or RMP alone, suggesting that this PMAA/INH/RMP nanogel could be a more useful dosage form than separate doses of INH and RMP for intestinal MTB. The novel aspects of this study include the cytotoxicity study and the three-phase release profile study, which might be useful for other researchers in this field.",
        "keywords": [
            "Cytotoxicity",
            "Intestinal tuberculosis",
            "Long-term activity",
            "Multidrug-resistant Mycobacterium tuberculosis",
            "Nanogel"
        ],
        "venue": "Materials Science and Engineering C",
        "year": 2016,
        "id": "pUJWQxRI"
    },
    "hrm27D4a": {
        "authors": [
            {
                "name": "Ding-Lun Ai",
                "org": "Department of Interventional Radiology"
            },
            {
                "name": "Bo-Tao Li",
                "org": "Department of Hematopoietic Stem Cell Transplantation"
            },
            {
                "name": "Xiao-Ming Peng",
                "org": "Department of Interventional Radiology"
            },
            {
                "name": "Lin-Zhi Zhang",
                "org": "Department of Interventional Radiology"
            },
            {
                "name": "Jing-Yan Wang",
                "org": "Department of Interventional Radiology"
            },
            {
                "name": "Yun Zhao",
                "org": "Department of Interventional Radiology"
            },
            {
                "name": "Bin Yang",
                "org": "Department of Interventional Radiology"
            },
            {
                "name": "Qiang Yu",
                "org": "Department of Interventional Radiology"
            },
            {
                "name": "Chun-Zi Liu",
                "org": "Department of Interventional Radiology"
            },
            {
                "name": "Ning Yang",
                "org": "Department of Clinical Laboratory"
            },
            {
                "name": "Hua-Ming Wang",
                "org": "Department of Interventional Radiology"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Interventional Radiology"
            }
        ],
        "title": "Acquired amegakaryocytic thrombocytopenic purpura induced by percutaneous ethanol injection during treatment of hepatocellular carcinoma: A case report",
        "abstract": "Percutaneous ethanol injection is an important localized treatment method for patients presenting with hepatocellular carcinoma (HCC). Among the advantages of percutaneous ethanol injection are its minimal invasiveness, simplicity, low cost and low risk of complications. However, the increasing popularity of percutaneous ethanol injection has resulted in serious adverse effects attributed to individual variations. The present study describes the case of a patient who exhibited acquired amegakaryocytic thrombocytopenic purpura, caused by percutaneous ethanol injection treatment for HCC. This complication was promptly identified, and platelet transfusion and injection of recombinant human interleukin-11 resulted in a rapid recovery of the patient's platelet count. Attention should be given to this rare complication in patients administered percutaneous ethanol injection treatment for HCC.",
        "keywords": [
            "Acquired amegakaryocytic thrombocytopenic purpura",
            "Complication",
            "Hepatocellular carcinoma",
            "Percutaneous ethanol injection"
        ],
        "venue": "Oncology Letters",
        "year": 2016,
        "id": "hrm27D4a"
    },
    "0i9dKlBC": {
        "authors": [
            {
                "name": "Hangxiang Wang",
                "org": "First Affiliated Hospital, School of Medicine, Zhejiang University"
            },
            {
                "name": "Wei Chen",
                "org": "Zhejiang University, School of Medicine"
            },
            {
                "name": "Haiyang Xie",
                "org": "First Affiliated Hospital, School of Medicine, Zhejiang University"
            },
            {
                "name": "Xuyong Wei",
                "org": "First Affiliated Hospital, School of Medicine, Zhejiang University"
            },
            {
                "name": "Shengyong Yin",
                "org": "First Affiliated Hospital, School of Medicine, Zhejiang University"
            },
            {
                "name": "Lin Zhou",
                "org": "First Affiliated Hospital, School of Medicine, Zhejiang University"
            },
            {
                "name": "Xiao Xu",
                "org": "First Affiliated Hospital, School of Medicine, Zhejiang University"
            },
            {
                "name": "Shusen Zheng",
                "org": "First Affiliated Hospital, School of Medicine, Zhejiang University"
            }
        ],
        "title": "Biocompatible, chimeric peptide-condensed supramolecular nanoparticles for tumor cell-specific siRNA delivery and gene silencing",
        "abstract": "Chimeric peptides composed of arginine-rich RNA-binding and tumor cell-targeting motifs have been employed to condense siRNA to form supramolecular nanoparticles via electrostatic associations and deliver siRNA agents in a tumor cell-specific manner. This journal is \u00a9 the Partner Organisations 2014.",
        "keywords": [
            ""
        ],
        "venue": "Chemical Communications",
        "year": 2014,
        "id": "0i9dKlBC"
    },
    "6TIQP06j": {
        "authors": [
            {
                "name": "Sheng Yan",
                "org": "Key Laboratory of Organ Transplantation Zhejiang Province, The First Affiliated Hospital, School of Medicine, Zhejiang University"
            },
            {
                "name": "Yuan Ding",
                "org": "Key Laboratory of Organ Transplantation Zhejiang Province, The First Affiliated Hospital, School of Medicine, Zhejiang University"
            },
            {
                "name": "Yang Tian",
                "org": "Key Laboratory of Organ Transplantation Zhejiang Province, The First Affiliated Hospital, School of Medicine, Zhejiang University"
            },
            {
                "name": "Zhongjie Lu",
                "org": "Key Laboratory of Organ Transplantation Zhejiang Province, The First Affiliated Hospital, School of Medicine, Zhejiang University"
            },
            {
                "name": "Yan Wang",
                "org": "Key Laboratory of Organ Transplantation Zhejiang Province, The First Affiliated Hospital, School of Medicine, Zhejiang University"
            },
            {
                "name": "Qiyi Zhang",
                "org": "Key Laboratory of Organ Transplantation Zhejiang Province, The First Affiliated Hospital, School of Medicine, Zhejiang University"
            },
            {
                "name": "Yufu Ye",
                "org": "Key Laboratory of Organ Transplantation Zhejiang Province, The First Affiliated Hospital, School of Medicine, Zhejiang University"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Organ Transplantation Zhejiang Province, The First Affiliated Hospital, School of Medicine, Zhejiang University"
            },
            {
                "name": "Haiyang Xie",
                "org": "Key Laboratory of Organ Transplantation Zhejiang Province, The First Affiliated Hospital, School of Medicine, Zhejiang University"
            },
            {
                "name": "Hui Chen",
                "org": "Key Laboratory of Organ Transplantation Zhejiang Province, The First Affiliated Hospital, School of Medicine, Zhejiang University"
            },
            {
                "name": "Minghao Zheng",
                "org": "Centre for Orthopaedic Research, School of Surgery, University of Western Australia"
            },
            {
                "name": "Shusen Zheng",
                "org": "Key Laboratory of Organ Transplantation Zhejiang Province, The First Affiliated Hospital, School of Medicine, Zhejiang University"
            }
        ],
        "title": "MHC-mismatched mice liver transplantation promotes tumor growth in liver graft",
        "abstract": "Liver transplantation is a final therapeutic option for treatment of hepatic malignancies, but local recurrence remains high after surgery. However, the underlying mechanisms of local tumor recurrence are still unknown. We speculated that immunological status of transplanted liver may contribute to the progress of tumor development. CT-26 tumor cells are injected into graft after allogeneic or syngeneic liver transplantation. The growth pattern of tumor and the co-relationship of regulatory T cell and effector T cells in liver graft were observed and investigated at 3d, 6d, 9d and 15d post-transplantation. The Hepatic Replacement Area of tumor in allogeneic grafts was significantly larger than that in syngeneic grafts. The activation of tumor growth in allografts was due to the dysfunction of effector T cells mediated by regulatory T cells in liver graft. Using nude mice model, we further confirmed that regulatory T cells from allograft significantly weaken the function of effector T cells in vivo. Our data has showed that MHC-mismatched mice liver transplantation can promote tumor growth in liver graft. For the first time, we demonstrated that susceptibility to tumor development in liver graft is due to the down-regulation of effector T cells' function mediated by the regulatory T cells. \u00a9 2014 Elsevier Ireland Ltd.",
        "keywords": [
            "Allogeneic",
            "Graft",
            "Immune-environment",
            "Liver transplantation",
            "Mouse"
        ],
        "venue": "Cancer Letters",
        "year": 2014,
        "id": "6TIQP06j"
    },
    "IxuBNrhR": {
        "authors": [
            {
                "name": "Chengjun Jiang",
                "org": "Department of Chemical and Biological Engineering, Zhejiang University of Science and Technology"
            },
            {
                "name": "Hangxiang Wang",
                "org": "First Affiliated Hospital, School of Medicine, Zhejiang University"
            },
            {
                "name": "Xiaomin Zhang",
                "org": "Hangzhou PushiKang Biotechnology Co., Ltd."
            },
            {
                "name": "Zhibin Sun",
                "org": "Hangzhou PushiKang Biotechnology Co., Ltd."
            },
            {
                "name": "Feng Wang",
                "org": "College of Life and Environmental Science, Shanghai Normal University"
            },
            {
                "name": "Jun Cheng",
                "org": "First Affiliated Hospital, School of Medicine, Zhejiang University"
            },
            {
                "name": "Haiyang Xie",
                "org": "First Affiliated Hospital, School of Medicine, Zhejiang University"
            },
            {
                "name": "Bo Yu",
                "org": "Hangzhou PushiKang Biotechnology Co., Ltd."
            },
            {
                "name": "Lin Zhou",
                "org": "First Affiliated Hospital, School of Medicine, Zhejiang University"
            }
        ],
        "title": "Deoxycholic acid-modified chitooligosaccharide/mPEG-PDLLA mixed micelles loaded with paclitaxel for enhanced antitumor efficacy",
        "abstract": "Poly(ethylene glycol) (PEG) as a block in polymeric micelles can prolong circulation life and reduce systemic clearance but decrease the cellular uptake. To overcome this limitation, a mixed micelle composed of deoxycholic acid-modified chitooligosaccharide (COS-DOCA) and methoxy poly(ethylene glycol)-polylactide copolymer (mPEG-PDLLA) was designed to load paclitaxel (PTX). The PTX-loaded mixed micelles was prepared by nanoprecipitation method with high drug-loading efficiency of 8.03% and encapsulation efficiency of 97.09% as well as small size (\u223c40 nm) and narrow size distribution. COS-DOCA/mPEG-PDLLA mixed micelles exhibited the sustained release property. Due to the positive charge and bioadhesive property of COS-DOCA, the cellular uptake of PTX in mixed micelles was higher in cancer cells but lower in macrophage cells compared to the mPEG-PDLLA micelles. The systemic toxicity of PTX in mixed micelles was much lower than Taxol using zebrafish as a toxicological model. Furthermore, the PTX-loaded COS-DOCA/mPEG-PDLLA mixed micelles can prolong the blood circulation time of PTX and enhance the antitumor efficacy in A549 lung xenograft model. Our findings indicate that COS-DOCA/mPEG-PDLLA mixed micelles could be a potential vehicle for enhanced delivery of anticancer drugs. \u00a9 2014 Elsevier B.V.",
        "keywords": [
            "Chitooligosaccharide",
            "Mixed micelles",
            "Paclitaxel",
            "PEG-PDLLA",
            "Polymeric micelles"
        ],
        "venue": "International Journal of Pharmaceutics",
        "year": 2014,
        "id": "IxuBNrhR"
    },
    "54SpRuYL": {
        "authors": [
            {
                "name": "Xihao Zhang",
                "org": "Department of Electronic Engineering, Shanghai Jiao Tong University"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Electronic Engineering, Shanghai Jiao Tong University"
            },
            {
                "name": "Tao Zhang",
                "org": "Department of Automation, Shanghai Jiao Tong University"
            },
            {
                "name": "Jie Yang",
                "org": "Department of Automation, Shanghai Jiao Tong University"
            }
        ],
        "title": "A novel efficient method for abnormal face detection in ATM",
        "keywords": [
            ""
        ],
        "venue": "ICALIP 2014 - 2014 International Conference on Audio, Language and Image Processing, Proceedings",
        "year": 2015,
        "id": "54SpRuYL"
    },
    "vWfZ8yoY": {
        "authors": [
            {
                "name": "Yuqin Shen",
                "org": "Departments of Cardiology, Tongji Hospital Affiliated to Tongji University"
            },
            {
                "name": "Xiaoyu Zhang",
                "org": "Departments of Rheumatology, Tongji Hospital Affiliated to Tongji University"
            },
            {
                "name": "Wenlin Ma",
                "org": "Departments of Cardiology, Tongji Hospital Affiliated to Tongji University"
            },
            {
                "name": "Haoming Song",
                "org": "Departments of Cardiology, Tongji Hospital Affiliated to Tongji University"
            },
            {
                "name": "Zhu Gong",
                "org": "Departments of Cardiology, Tongji Hospital Affiliated to Tongji University"
            },
            {
                "name": "Qiang Wang",
                "org": "Departments of Cardiology, Tongji Hospital Affiliated to Tongji University"
            },
            {
                "name": "Lin Che",
                "org": "Departments of Cardiology, Tongji Hospital Affiliated to Tongji University"
            },
            {
                "name": "Wenjun Xu",
                "org": "Departments of Cardiology, Tongji Hospital Affiliated to Tongji University"
            },
            {
                "name": "Jinfa Jiang",
                "org": "Departments of Cardiology, Tongji Hospital Affiliated to Tongji University"
            },
            {
                "name": "Jiahong Xu",
                "org": "Departments of Cardiology, Tongji Hospital Affiliated to Tongji University"
            },
            {
                "name": "Wenwen Yan",
                "org": "Departments of Cardiology, Tongji Hospital Affiliated to Tongji University"
            },
            {
                "name": "Lin Zhou",
                "org": "Departments of Cardiology, Tongji Hospital Affiliated to Tongji University"
            },
            {
                "name": "Yi Ni",
                "org": "Departments of Cardiology, Tongji Hospital Affiliated to Tongji University"
            },
            {
                "name": "Guanghe Li",
                "org": "Departments of Cardiology, Tongji Hospital Affiliated to Tongji University"
            },
            {
                "name": "Qiping Zhang",
                "org": "Departments of Cardiology, Tongji Hospital Affiliated to Tongji University"
            },
            {
                "name": "Lemin Wang",
                "org": "Departments of Cardiology, Tongji Hospital Affiliated to Tongji University"
            }
        ],
        "title": "VE/VCO2 slope and its prognostic value in patients with chronic heart failure",
        "abstract": "The minute ventilation/carbon dioxide production (VE/VCO",
        "keywords": [
            "Cardiopulmonary exercise test",
            "Heart failure",
            "Ventilatory expired gas"
        ],
        "venue": "Experimental and Therapeutic Medicine",
        "year": 2015,
        "id": "vWfZ8yoY"
    },
    "rZ8Mfhvf": {
        "authors": [
            {
                "name": "Jun Yao",
                "org": ""
            },
            {
                "name": "Jia Li",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Jianwen Cheng",
                "org": ""
            },
            {
                "name": "Shek Man Chim",
                "org": ""
            },
            {
                "name": "Ge Zhang",
                "org": ""
            },
            {
                "name": "Julian M.W. Quinn",
                "org": ""
            },
            {
                "name": "Jennifer Tickner",
                "org": ""
            },
            {
                "name": "Jinmin Zhao",
                "org": ""
            },
            {
                "name": "Jiake Xu",
                "org": ""
            }
        ],
        "title": "Protein Kinase C Inhibitor, GF109203X Attenuates Osteoclastogenesis, Bone Resorption and RANKL-Induced NF-\u03baB and NFAT Activity",
        "abstract": "Osteolytic bone diseases are characterized by excessive osteoclast formation and activation. Protein kinase C (PKC)-dependent pathways regulate cell growth, differentiation and apoptosis in many cellular systems, and have been implicated in cancer development and osteoclast formation. A number of PKC inhibitors with anti-cancer properties have been developed, but whether they might also influence osteolysis (a common complication of bone invading cancers) is unclear. We studied the effects of the PKC inhibitor compound, GF109203X on osteoclast formation and activity, processes driven by receptor activator of NF\u03baB ligand (RANKL). We found that GF109203X strongly and dose dependently suppresses osteoclastogenesis and osteoclast activity in RANKL-treated primary mouse bone marrow cells. Consistent with this GF109203X reduced expression of key osteoclastic genes, including cathepsin K, calcitonin receptor, tartrate resistant acid phosphatase (TRAP) and the proton pump subunit V-ATPase-d2 in RANKL-treated primary mouse bone marrow cells. Expression of these proteins is dependent upon RANKL-induced NF-\u03baB and NFAT transcription factor actions; both were reduced in osteoclast progenitor populations by GF109203X treatment, notably NFATc1 levels. Furthermore, we showed that GF109203X inhibits RANKL-induced calcium oscillation. Together, this study shows GF109203X may block osteoclast functions, suggesting that pharmacological blockade of PKC-dependent pathways has therapeutic potential in osteolytic diseases. J. Cell. Physiol. 230: 1235-1242, 2015.",
        "keywords": [
            ""
        ],
        "venue": "Journal of Cellular Physiology",
        "year": 2015,
        "id": "rZ8Mfhvf"
    },
    "RrrtKOtp": {
        "authors": [
            {
                "name": "Zhiyun Zheng",
                "org": ""
            },
            {
                "name": "Bingyi Lin",
                "org": ""
            },
            {
                "name": "Jing Zhang",
                "org": ""
            },
            {
                "name": "Zhe Yang",
                "org": ""
            },
            {
                "name": "Haiyang Xie",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Min Zhang",
                "org": ""
            },
            {
                "name": "Shusen Zheng",
                "org": ""
            }
        ],
        "title": "Absolute lymphocyte count recovery at 1 month after transplantation predicts favorable outcomes of patients with hepatocellular carcinoma",
        "abstract": "Background and Aims: Absolute lymphocyte count (ALC) and the recovery of ALC after treatment have been identified as a prognostic biomarker for several malignancies. In this study, we aimed to investigate the prognostic role of peritransplant ALC and ALC recovery after liver transplantation (LT) in hepatocellular carcinoma (HCC) patients. Methods: A total of 269 HCC patients undergoing LT were enrolled in our study. Clinicopathological data were retrospectively collected and reviewed. Peritransplant ALC and the change of ALC (2 weeks, 1 month, 3 months post-LT) were carefully monitored. All potential risk factors were analyzed by univariate and multivariate cox regression analysis. Results: Over a mean follow-up of 35.9 months, 120 recurrences and 89 deaths were recorded. In the multivariate analysis, HCC with ALC no recovery at 1 month after LT (P<0.001), high pretransplant alpha fetoprotein (P=0.010), total tumor size >8cm (P=0.003), and beyond Milan criteria (P<0.001) were four independent risk factors for HCC recurrence. For overall survival (OS) after LT, ALC no recovery at 1 month after LT (P=0.003), total tumor size >8cm (P=0.011), pretransplant albumin <2.8g/dL (P=0.049), model of end-stage liver disease score >15 (P=0.017), and beyond Milan criteria (P=0.001) were significantly related to poor OS. When subgroup analyses were performed according to the Milan criteria, the results showed that the recovery of ALC at 1 month after LT still indicated longer recurrence-free survival (RFS) (P<0.001) and OS (P=0.005) beyond Milan criteria as well as RFS (P<0.001) within Milan criteria, but not OS (P=0.157) within Milan criteria. Conclusions: ALC recovery at 1 month after LT indicated favorable outcomes of HCC patients.",
        "keywords": [
            "Absolute lymphocyte count recovery",
            "Hepatocellular carcinoma",
            "Liver transplantation",
            "Prognosis"
        ],
        "venue": "Journal of Gastroenterology and Hepatology (Australia)",
        "year": 2015,
        "id": "RrrtKOtp"
    },
    "wRl3J3Vo": {
        "authors": [
            {
                "name": "Chaofeng Ding",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Zhe Yang",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University"
            },
            {
                "name": "Zhen Lv",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Chengli Du",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Heng Xiao",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Chuanhui Peng",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University"
            },
            {
                "name": "Shaobing Cheng",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Haiyang Xie",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Jian Wu",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Shusen Zheng",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation, Ministry of Public Health"
            }
        ],
        "title": "Long non-coding RNA PVT1 is associated with tumor progression and predicts recurrence in hepatocellular carcinoma patients",
        "keywords": [
            "Hepatocellular carcinoma",
            "Long non-coding RNA",
            "Progression",
            "PVT1",
            "Recurrence"
        ],
        "venue": "Oncology Letters",
        "year": 2015,
        "id": "wRl3J3Vo"
    },
    "TUxHucCj": {
        "authors": [
            {
                "name": "Bin Liu",
                "org": ""
            },
            {
                "name": "Huifen Xu",
                "org": ""
            },
            {
                "name": "Jiangfang Miao",
                "org": ""
            },
            {
                "name": "Andy Zhang",
                "org": ""
            },
            {
                "name": "Xiaojin Kou",
                "org": ""
            },
            {
                "name": "Wen Li",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Hong-Guang Xie",
                "org": ""
            },
            {
                "name": "Pierre Sirois",
                "org": ""
            },
            {
                "name": "Kai Li",
                "org": ""
            }
        ],
        "title": "CRISPR/Cas: A faster and more efficient gene editing system",
        "abstract": "Gene editing technology has been at its mature stage with the successful development of TALENs and CRISPR/Cas enzymes. The genetically modified endonucleases of ZFNs, TALENs, and CRISPR/Cas are widely used in the development of genetically modified cells or organisms. Among the enzymes that possess gene editing ability, CRISPR/Cas is the latest member with high efficiency in gene editing and simplicity in cloning. This review discusses the discovery of CRISPR, the development of the CRISPR/Cas system, and its applications as a new gene editing system.",
        "keywords": [
            "CRISPR/Cas",
            "Endonuclease",
            "Gene editing"
        ],
        "venue": "Journal of Nanoscience and Nanotechnology",
        "year": 2015,
        "id": "TUxHucCj"
    },
    "jSHiSrqx": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Department of Ophthalmology, Central Hospital of Enshi Autonomous Prefecture, Enshi Clinical College of Wuhan University"
            },
            {
                "name": "Tuo Li",
                "org": "Department of Ophthalmology, Central Hospital of Enshi Autonomous Prefecture, Enshi Clinical College of Wuhan University"
            },
            {
                "name": "Xiusheng Song",
                "org": "Department of Ophthalmology, Central Hospital of Enshi Autonomous Prefecture, Enshi Clinical College of Wuhan University"
            },
            {
                "name": "Yin Li",
                "org": "Department of Ophthalmology, Central Hospital of Enshi Autonomous Prefecture, Enshi Clinical College of Wuhan University"
            },
            {
                "name": "Hongyan Li",
                "org": "Department of Ophthalmology, Central Hospital of Enshi Autonomous Prefecture, Enshi Clinical College of Wuhan University"
            },
            {
                "name": "Handong Dan",
                "org": "Department of Ophthalmology, Central Hospital of Enshi Autonomous Prefecture, Enshi Clinical College of Wuhan University"
            }
        ],
        "title": "NYX mutations in four families with high myopia with or without CSNB1",
        "abstract": "Purpose: Mutations in the NYX gene are known to cause complete congenital stationary night blindness (CSNB1), which is always accompanied by high myopia. In this study, we aimed to investigate the association between NYX mutations and high myopia with or without CSNB1. Methods: Four Chinese families having high myopia with or without CSNB1 and 96 normal controls were recruited. We searched for mutations in the NYX gene using Sanger sequencing. Further analyses of the detected variations in the available family members were performed, and the frequencies of the detected variations in 96 normal controls were determined to verify our deduction. The effect of each variation on the nyctalopin protein was predicted using online tools. Results: Four potential pathogenic variations in the NYX gene were found in four families with high myopia with or without CSNB1. Three of the four variants were novel (c.626G>C; c.121delG; c.335T>C). The previously identified variant, c.529_530delGCinsAT, was found in an isolated highly myopic patient and an affected brother, but the other affected brother did not carry the same variation. Further linkage analyses of this family showed a coinheritance of markers at MYP1. These four mutations were not identified in the 96 normal controls. Conclusions: Our study expands the mutation spectrum of NYX for cases of high myopia with CSNB1; however, more evidence is needed to elucidate the pathogenic effects of NYX on isolated high myopia.",
        "keywords": [
            ""
        ],
        "venue": "Molecular Vision",
        "year": 2015,
        "id": "jSHiSrqx"
    },
    "UhNUwKTA": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "Department of Material Science and Engineering, China Jiliang University"
            },
            {
                "name": "Xiaoling Peng",
                "org": "Department of Material Science and Engineering, China Jiliang University"
            },
            {
                "name": "Xinqing Wang",
                "org": "Department of Material Science and Engineering, China Jiliang University"
            },
            {
                "name": "Dingfeng Jin",
                "org": "Department of Material Science and Engineering, China Jiliang University"
            },
            {
                "name": "Hongxiao Jin",
                "org": "Department of Material Science and Engineering, China Jiliang University"
            },
            {
                "name": "Hongliang Ge",
                "org": "Department of Material Science and Engineering, China Jiliang University"
            }
        ],
        "title": "Preparation and characterization of graphene/Fe3O4 composites by solvothermal method",
        "abstract": "In the present study, graphene/Fe",
        "keywords": [
            "Graphene/Fe3O4 nanocomposites",
            "Magnetic properties",
            "Microstructures",
            "Morphologies",
            "Sovolthermal method"
        ],
        "venue": "Journal of Nanoscience and Nanotechnology",
        "year": 2015,
        "id": "UhNUwKTA"
    },
    "JgIT0DBh": {
        "authors": [
            {
                "name": "Xuyong Wei",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Jie Li",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Haiyang Xie",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Qi Ling",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, Zhejiang University School of Medicine"
            },
            {
                "name": "Jianguo Wang",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Di Lu",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Xiao Xu",
                "org": "Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases"
            },
            {
                "name": "Shusen Zheng",
                "org": "Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases"
            }
        ],
        "title": "Proteomics-based identification of the tumor suppressor role of aminoacylase 1 in hepatocellular carcinoma",
        "abstract": "The present work aimed to investigate the expression and role of aminoacylase 1 (ACY1) in hepatocellular carcinoma (HCC) based on a proteomic study. The study results revealed that the expression of ACY1 was much lower in HCC tissues. ACY1 expression significantly correlated with the serum alpha fetoprotein level and tumor invasiveness. The knockdown of ACY1 in SMMC7721 cells promoted cell viability and invasiveness. In contrast, the restoration of ACY1 in BEL7402 cells inhibited cell viability and invasiveness. Further studies indicated that the knockdown of ACY1 increased the protein expression of transforming growth factor beta 1 and extracellular signal-regulated kinase 1 expression. The study's results indicated that ACY1 acts as a tumor suppressor in HCC. \u00a9 2014 Elsevier Ireland Ltd.",
        "keywords": [
            "Aminoacylase 1",
            "Hepatocellular carcinoma",
            "Proteomic",
            "Tumor suppressor"
        ],
        "venue": "Cancer Letters",
        "year": 2014,
        "id": "JgIT0DBh"
    },
    "JdSNYkEH": {
        "authors": [
            {
                "name": "Heng Xiao",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Rongliang Tong",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Chaofeng Ding",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Zhen Lv",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Chengli Du",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Chuanhui Peng",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Shaobing Cheng",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Haiyang Xie",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Jian Wu",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Shusen Zheng",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            }
        ],
        "title": "\u03b3-H2AX promotes hepatocellular carcinoma angiogenesis via EGFR/HIF-1\u03b1/VEGF pathways under hypoxic condition",
        "keywords": [
            "Epidermal growth factor receptor(EGFR)",
            "Hepatocellular carcinoma (HCC)",
            "Hypoxia inducible factor 1a (HIF-1\u03b1)",
            "Vascular endothelial growth factor (VEGF)",
            "\u03b3-H2AX",
            "angiogenesis"
        ],
        "venue": "Oncotarget",
        "year": 2015,
        "id": "JdSNYkEH"
    },
    "phu9o9jE": {
        "authors": [
            {
                "name": "Zheng-Tao Liu",
                "org": "Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases"
            },
            {
                "name": "Tian-Chi Chen",
                "org": "Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases"
            },
            {
                "name": "Xiao-Xiao Lu",
                "org": "Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases"
            },
            {
                "name": "Jun Cheng",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, School of Medicine, Zhejiang University"
            },
            {
                "name": "Hai-Yang Xie",
                "org": "Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases"
            },
            {
                "name": "Lin Zhou",
                "org": "Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, School of Medicine, Zhejiang University"
            }
        ],
        "title": "PNPLA3 I148M variant affects non-alcoholic fatty liver disease in liver transplant recipients",
        "abstract": "De novo non-alcoholic fatty liver disease (NAFLD) is a common late complication for long-term survivors after liver transplantation. Genomic studies confirmed that PNPLA3 I148M and TM6SF2 E167K polymorphisms affected NAFLD susceptibility in the general population. However, this association was not validated in survivors after liver transplantation (LT). We performed a crosssectional survey to investigate this relationship. A comprehensive survey, including anthropometric measurements, fasting venous blood sampling, ultrasound, and questionnaires was performed in the shortterm. The clinical indications and patient's steatosis status before LT were collected from inpatient medical records. Sixty-five long-term recipients with a survival exceeding 10 years were enrolled in the final analysis. De novo NAFLD was more frequent in PNPLA3 GG carriers (0.33 vs 0.10 for GG vs CC + CG carriers, P = 0.018), while the genetic impact on NAFLD susceptibility was insignificant when categorized by the TM6SF2 polymorphism (0.19 in CC vs 0.14 in CT + TT carriers, P = 0.883). Multi-covariate analysis revealed that PNPLA3 exerted a significant genetic effect on de novo NAFLD following a recessive model (GG vs CC + CG, OR = 14.2, 95%CI: 1.78-113, P = 0.012). Compared to recipients with only the PNPLA3 GG allele or obesity (defined as body mass index > 25 kg/m2), steatosis was highly prevalent (71.4%) in PNPLA3 GG carriers with obesity. In conclusion, PNPLA3 I148M, but not TM6SF2 E167K, affects de novo NAFLD occurrence with a prominent interaction with obesity. Weight control might be a meaningful method to reduce the genetic susceptibility to NAFLD exerted by PNPLA3 variants.",
        "keywords": [
            "Liver transplantation",
            "Non-alcoholic fatty liver disease",
            "PNPLA3",
            "Recipient",
            "TM6SF2"
        ],
        "venue": "World Journal of Gastroenterology",
        "year": 2015,
        "id": "phu9o9jE"
    },
    "KEEGMWP1": {
        "authors": [
            {
                "name": "Jun-Jun Jia",
                "org": ""
            },
            {
                "name": "Jing Zhang",
                "org": ""
            },
            {
                "name": "Jian-Hui Li",
                "org": ""
            },
            {
                "name": "Xu-Dong Chen",
                "org": ""
            },
            {
                "name": "Li Jiang",
                "org": ""
            },
            {
                "name": "Yan-Fei Zhou",
                "org": ""
            },
            {
                "name": "Ning He",
                "org": ""
            },
            {
                "name": "Hai-Yang Xie",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "S.-S.Z. Shu-Sen Zheng",
                "org": ""
            }
        ],
        "title": "Influence of perfusate on liver viability during hypothermic machine perfusion",
        "abstract": "AIM: To optimize the perfusates used for hypothermic METHODS: Sprague-Dawley rats were assigned randomly to three groups (n = 12 per group) that received either saline, University of Wisconsin coldstorage solution (UW) or histidine-tryptophanketoglutarate solution (HTK) as the perfusate. Each group was divided into two subgroups: static cold storage (SCS) and HMP (n = 6 per subgroup). The liver graft was retrieved according to the method described by Kamada. For the SCS group, the graft was directly placed into cold perfusate (0-4 ?) for 6 h after liver isolation while the portal vein of the graft was connected to the perfusion machine for the HMP group. Then the perfusates were collected at different time points for analysis of aspartate aminotransferase (AST), alanine transaminase (ALT) and lactate dehydrogenase (LDH) levels. Liver tissues were obtained for evaluation of histology, dry/wet weight (D/W) ratio, and malondialdehyde (MDA) and adenosine-triphosphate (ATP) levels. The portal vein pressure and velocity were monitored in real time in all HMP subgroups. RESULTS: Comparison of HMP and SCS: Regardless of the perfusate, HMP improved the architecture of donor graft in reducing the congestion around sinusoids and central vein and maintaining sinusoid lining in morphology; HMP improved liver function in terms of ALT, AST and LDH, especially during the 3-6 h period (SCS vs HMP using saline: ALT3, 225.00 \u00b1 105.62 vs 49.50 \u00b1 18.50, P = 0.047; LDH3, 1362.17 \u00b1 563.30 vs 325.75 \u00b1 147.43, P = 0.041; UW: LDH6, 2880.14 \u00b1 948.46 vs 2135.00 \u00b1 174.27, P = 0.049; HTK, AST6, 307.50 \u00b1 52.95 vs 185.20 \u00b1 20.46, P = 0.041); HMP decreased MDA level (saline, 2.79 \u00b1 0.30 vs 1.09 \u00b1 0.09, P = 0.008; UW, 3.01 \u00b1 0.77 vs 1.23 \u00b1 0.68, P = 0.005; HTK, 3.30 \u00b1 0.52 vs 1.56 \u00b1 0.22, P = 0.006). Comparison among HMP subgroups: HTK showed less portal vein resistance than UW and saline (vs saline, 3.41 \u00b1 0.49 vs 5.00 \u00b1 0.38, P< 0.001; vs UW, 3.41 \u00b1 0.49 vs 4.52 \u00b1 0.63, P = 0.007); UW reduced edema most efficiently (vs saline, 0.68 \u00b1 0.02 vs 0.79 \u00b1 0.05, P = 0.013), while HTK maintained ATP levels best (vs saline, 622.60 \u00b1 29.11 vs 327.43 \u00b1 44.66, P < 0.001; vs UW, 622.60 \u00b1 29.11 vs 301.80 \u00b1 37.68, P < 0.001). CONCLUSION: HMP is superior to SCS in maintaining both architecture and function of liver grafts. Further, HTK was found to be the optimal perfusate for HMP.",
        "keywords": [
            "Histidine-tryptophan-ketoglutarate solution",
            "Hypothermic machine perfusion",
            "Liver viability",
            "Static cold storage",
            "Wisconsin cold-storage solution"
        ],
        "venue": "World Journal of Gastroenterology",
        "year": 2015,
        "id": "KEEGMWP1"
    },
    "pXOBwRGk": {
        "authors": [
            {
                "name": "Weilin Wang",
                "org": ""
            },
            {
                "name": "Pengfei Huang",
                "org": ""
            },
            {
                "name": "Panyisha Wu",
                "org": ""
            },
            {
                "name": "Rong Kong",
                "org": ""
            },
            {
                "name": "Jiang Xu",
                "org": ""
            },
            {
                "name": "Lufei Zhang",
                "org": ""
            },
            {
                "name": "Qifan Yang",
                "org": ""
            },
            {
                "name": "Qingsong Xie",
                "org": ""
            },
            {
                "name": "Linshi Zhang",
                "org": ""
            },
            {
                "name": "Xiaohu Zhou",
                "org": ""
            },
            {
                "name": "Linghui Chen",
                "org": ""
            },
            {
                "name": "Haiyang Xie",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Shusen Zheng",
                "org": ""
            }
        ],
        "title": "BCL6B expression in hepatocellular carcinoma and its efficacy in the inhibition of liver damage and fibrogenesis",
        "abstract": "B cell CLL/lymphoma 6 member B (BCL6B) is expressed in many normal tissues but expressed at very low levels in cancer tissues. It was reported that BCL6B inhibits hepatocellular carcinoma (HCC) metastases, but the exact role of BCL6B in HCC remains to be investigated. BCL6B expression was significantly decreased in HCC tissues compared with paired non-cancer tissues. Low BCL6B expression in tumors was correlated with shorter overall survival in patients, and multivariate Cox regression analysis revealed that BCL6B expression was an independent prognostic factor for human HCC patients. Moreover, a positive correlation between BCL6B expression and hepatic cirrhosis was found in an analysis of HCC clinicopathological characteristics. BCL6B expression was increased in rat fibrotic liver samples in response to liver injury. BCL6B transgenic rats were less susceptible to hepatocellular damage, inflammation and fibrosis. In vitro studies demonstrated that BCL6B inhibited the activation of hepatic stellate cells though upregulation of hepatocyte growth factor. In addition, transcriptomic microarray analysis was performed to explore the mechanisms in which BCL6B confers protection from tumorigenesis. In conclusion, BCL6B plays a pivotal role as a prognostic biomarker for HCC, and the restoration of BCL6B may be a novel strategy as an anti-fibrogenic therapy for human HCC.",
        "keywords": [
            "BCL6B",
            "Hepatocellular carcinoma",
            "Liver fibrosis",
            "Prognostic biomarker"
        ],
        "venue": "Oncotarget",
        "year": 2015,
        "id": "pXOBwRGk"
    },
    "U4aQ7T8r": {
        "authors": [
            {
                "name": "Xuyong Wei",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Jie Li",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Haiyang Xie",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Hangxiang Wang",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Jianguo Wang",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Xuanyu Zhang",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Runzhou Zhuang",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Di Lu",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Qi Ling",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, Zhejiang University School of Medicine"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Xiao Xu",
                "org": "Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases"
            },
            {
                "name": "Shusen Zheng",
                "org": "Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases"
            }
        ],
        "title": "Chloride intracellular channel 1 participates in migration and invasion of hepatocellular carcinoma by targeting maspin",
        "abstract": "Background and Aim: Our previous proteomic research found that chloride intracellular channel 1 (CLIC1) was upregulated in hepatocellular carcinoma (HCC) tissues with portal vein tumor thrombus. The present study aimed to determine the role of CLIC1 in HCC invasion. Methods: Immunohistochemistry was used to explore protein expression of CLIC1 in 15 cirrhotic tissues and 69 pairs of HCC and paracarcinoma tissues. Small interfering RNA (siRNA) and plasmids were transfected into HepG2 and SMMC7721 cells, and the in vitro function of CLIC1 in these cells were assessed with cell counting kit-8 assays, cell apoptosis assays, scratch assays, and transwell assays. Microarray analysis was also performed to further explore the candidate genes related to CLIC1. Results: Our results confirmed that upregulated CLIC1 expression was significantly correlated with vascular invasion (P=0.034) in HCC tissues. Knockdown of CLIC1 decreased cell viability and the invasive potency of HepG2 cells, whereas CLIC1 overexpression resulted in an opposite effect in SMMC7721 cells. Microarray analysis identified 618 genes that were differentially expressed (fold change \u22652, P<0.05) between HepG2 cells transfected with CLIC1 siRNA and the negative control. Further studies indicate that knockdown of CLIC1 increased maspin expression and reduced vascular endothelial growth factor (VEGF), matrixmetalloproteinase-2 (MMP2), MMP9, MMP11, and MMP12 expression. In contrast, overexpression of CLIC1 decreased maspin expression and increased VEGF, MMP2, MMP12, and MMP13 expression. Conclusions: CLIC1 protein expression is significantly correlated with vascular invasion, and the present study suggests a previously unknown mechanism of CLIC1-mediated control of HCC invasiveness by targeting maspin.",
        "keywords": [
            "Chloride intracellular channel 1",
            "Hepatocellular carcinoma",
            "Invasiveness",
            "Maspin"
        ],
        "venue": "Journal of Gastroenterology and Hepatology (Australia)",
        "year": 2015,
        "id": "U4aQ7T8r"
    },
    "b9tsOxUA": {
        "authors": [
            {
                "name": "Weilin Wang",
                "org": "Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases"
            },
            {
                "name": "Qingsong Xie",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Xiaohu Zhou",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Jingzi Yao",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Xiaoxiang Zhu",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Pengfei Huang",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Lufei Zhang",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Jianfeng Wei",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, Zhejiang University School of Medicine"
            },
            {
                "name": "Haiyang Xie",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Lab of Combined Multi-Organ Transplantation, Ministry of Public Health"
            },
            {
                "name": "Shusen Zheng",
                "org": "Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases"
            }
        ],
        "title": "Mitofusin-2 triggers mitochondria Ca",
        "abstract": "In previous studies, we confirmed that mitofusin-2 (Mfn2) induced apoptosis in hepatocellular carcinoma (HCC) cells. However, the exact molecular mechanism remained unclear. Mfn2 expressed lower in tumour tissues, compared with adjacent non-cancer tissues. Furthermore, Mfn2 immunostaining was very weak in HCC tissue (P < 0.05) and was significantly associated with tumour size and TNM stage (P = 0.038 and 0.040, respectively), and patients with HCC with lower Mfn2 expression had a poorer prognosis. Overexpression of Mfn2 induced HepG2 cells apoptosis, reduced the mitochondrial membrane potential (\u03b4\u03a8m) and endoplasmic reticulum (ER) calcium ion (Ca",
        "keywords": [
            "Heparin",
            "InsP3R",
            "Mitochondrial Ca2+ uniporter",
            "Mitochondrial calcium uptake 2",
            "Mitochondrial calcium uptake1",
            "RU360"
        ],
        "venue": "Cancer Letters",
        "year": 2015,
        "id": "b9tsOxUA"
    },
    "nDDIv7Ep": {
        "authors": [
            {
                "name": "Chengli Du",
                "org": "Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, First Affiliated Hospital, Zhejiang University"
            },
            {
                "name": "Xiaoyu Weng",
                "org": "Department of Hepatobiliary Surgery, First Affiliated Hospital, Zhejiang University"
            },
            {
                "name": "Wendi Hu",
                "org": "Department of Hepatobiliary Surgery, First Affiliated Hospital, Zhejiang University"
            },
            {
                "name": "Zhen Lv",
                "org": "Department of Hepatobiliary Surgery, First Affiliated Hospital, Zhejiang University"
            },
            {
                "name": "Heng Xiao",
                "org": "Department of Hepatobiliary Surgery, First Affiliated Hospital, Zhejiang University"
            },
            {
                "name": "Chaofeng Ding",
                "org": "Department of Hepatobiliary Surgery, First Affiliated Hospital, Zhejiang University"
            },
            {
                "name": "Owusu-Anash K. Gyabaah",
                "org": "Department of Hepatobiliary Surgery, First Affiliated Hospital, Zhejiang University"
            },
            {
                "name": "Haiyang Xie",
                "org": "Department of Hepatobiliary Surgery, First Affiliated Hospital, Zhejiang University"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Hepatobiliary Surgery, First Affiliated Hospital, Zhejiang University"
            },
            {
                "name": "Jian Wu",
                "org": "Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, First Affiliated Hospital, Zhejiang University"
            },
            {
                "name": "Shusen Zheng",
                "org": "Department of Hepatobiliary Surgery, First Affiliated Hospital, Zhejiang University"
            }
        ],
        "title": "Hypoxia-inducible MiR-182 promotes angiogenesis by targeting RASA1 in hepatocellular carcinoma",
        "keywords": [
            "Angiogenesis",
            "HCC",
            "Hypoxia",
            "miR-182",
            "RASA1"
        ],
        "venue": "Journal of Experimental and Clinical Cancer Research",
        "year": 2015,
        "id": "nDDIv7Ep"
    },
    "A2rpYxzQ": {
        "authors": [
            {
                "name": "Hui-Ting Wang",
                "org": "College of Chemistry and Chemical Engineering, Southeast University"
            },
            {
                "name": "Lin Zhou",
                "org": "College of Chemistry and Chemical Engineering, Southeast University"
            }
        ],
        "title": "A one-dimensional Cd<sup>II</sup> coordination polymer constructed from 4-(dimethylamino)pyridinium-1-acetate ligands and thiocyanate coordination bridges",
        "abstract": "A new cadmium-thiocyanate complex, namely catena-poly[1-carboxymethyl-4-(dimethylamino)pyridinium [cadmium(II)-tri-\u03bc-thiocyanato-\u03ba<sup>4</sup> N:S;\u03ba<sup>2</sup> S:N] [[[4-(dimethylamino)pyridinium-1-acetate-\u03ba<sup>2</sup> O,O\u2032]cadmium(II)]-di-\u03bc-thiocyanato-\u03ba<sup>2</sup> N:S;\u03ba<sup>2</sup> S:N]], {(C<inf>9</inf>H<inf>13</inf>N<inf>2</inf>O<inf>2</inf>)[Cd(NCS)<inf>3</inf>][Cd(NCS)<inf>2</inf>(C<inf>9</inf>H<inf>12</inf>N<inf>2</inf>O<inf>2</inf>)]}<inf>n</inf> , was synthesized by the reaction of 4-(dimethylamino)pyridinium-1-acetate, cadmium nitrate tetrahydrate and potassium thiocyanide in aqueous solution. In the crystal structure, two types of Cd<sup>II</sup> atoms are observed in distorted octahedral coordination environments. One type of Cd<sup>II</sup> atom is coordinated by two O atoms from the carboxylate group of the 4-(dimethylamino)pyridinium-1-acetate ligand and by two N atoms and two S atoms from four different thiocyanate ligands, while the second type of Cd<sup>II</sup> atom is coordinated by three N atoms and three S atoms from six different thiocyanate ligands. Neighbouring Cd<sup>II</sup> atoms are linked by thiocyanate bridges to form a one-dimensional zigzag chain and a one-dimensional coordination polymer. Hydrogen-bond interactions are involved in the formation of the supramolecular network.",
        "keywords": [
            "cadmium(II) complex",
            "crystal structure",
            "hydrogen bonding",
            "one-dimensional coordination polymer",
            "One-dimensional zigzag chain"
        ],
        "venue": "Acta Crystallographica Section C: Structural Chemistry",
        "year": 2015,
        "id": "A2rpYxzQ"
    },
    "ZxrJAw1T": {
        "authors": [
            {
                "name": "Qiang Li",
                "org": "Ordered Matter Science Research Center, Southeast University"
            },
            {
                "name": "Hui-Ting Wang",
                "org": "Ordered Matter Science Research Center, Southeast University"
            },
            {
                "name": "Lin Zhou",
                "org": "Ordered Matter Science Research Center, Southeast University"
            }
        ],
        "title": "A new three-dimensional CdII supramolecular framework constructed from the 1-[(1H-tetrazol-5-yl)methyl]-1,4-diazoniabicyclo[2.2.2]octane ligand",
        "abstract": "A new tetrazole-metal supramolecular compound, di-\u03bc-chlorido-bis(trichlorido{1-[(1H-tetrazol-5-yl-\u03baN",
        "keywords": [
            "crystal structure",
            "dinuclear cadmium complex",
            "hydrogen bonding",
            "supramolecular structure",
            "tetrazole ligand"
        ],
        "venue": "Acta Crystallographica Section C: Structural Chemistry",
        "year": 2015,
        "id": "ZxrJAw1T"
    },
    "Hzt3leky": {
        "authors": [
            {
                "name": "Hui-Ting Wang",
                "org": "Ordered Matter Science Research Center, College of Chemistry and Chemical Engineering, Southeast University"
            },
            {
                "name": "Qiang Li",
                "org": "Ordered Matter Science Research Center, College of Chemistry and Chemical Engineering, Southeast University"
            },
            {
                "name": "Lin Zhou",
                "org": "Ordered Matter Science Research Center, College of Chemistry and Chemical Engineering, Southeast University"
            }
        ],
        "title": "A two-dimensional cadmium(II) coordination polymer based on 1-cyanomethyl-4-aza-1-azoniabicyclo[2.2.2]octane and thiocyanate ligands",
        "abstract": "A cadmium-thiocyanate complex, poly[(1-cyanomethyl-4-aza-1-azoniabicyclo[2.2.2]octane-\u03ba<sup>4</sup> N)octakis-\u03bc2-thiocyanato-\u03ba<sup>8</sup> N:S;\u03ba<sup>8</sup> S:N-tricadmium(II)], [Cd3(C8H<inf>14</inf>N<inf>3</inf>)<inf>2</inf>(NCS)8] n , was synthesized by the reaction of 1-cyanomethyl-4-aza-1-azoniabicyclo[2.2.2]octane chloride, cadmium nitrate tetrahydrate and potassium thiocyanide in aqueous solution. In the crystal structure, there are two independent types of Cd<sup>II</sup> cation (one on a centre of inversion and one in a general position) and both are in distorted octahedral coordination environments, coordinated by N and S atoms from different ligands. Neighbouring Cd<sup>II</sup> cations are linked together by thiocyanate bridges to form a two-dimensional network. Hydrogen-bonding interactions are involved in the formation of a three-dimensional supramolecular network.",
        "keywords": [
            "cadmium-thiocyanate complex",
            "crystal structure",
            "hydrogen bonding",
            "two-dimensional coordination polymer"
        ],
        "venue": "Acta Crystallographica Section C: Structural Chemistry",
        "year": 2015,
        "id": "Hzt3leky"
    },
    "tBzo9meK": {
        "authors": [
            {
                "name": "Lin Zhou",
                "org": "College of Chemistry and Chemical Engineering, Southeast University"
            },
            {
                "name": "Hui-Ting Wang",
                "org": "College of Chemistry and Chemical Engineering, Southeast University"
            }
        ],
        "title": "A two-dimensional cadmium(II) polymer based on nicotinic acid and thiocyanate ligands",
        "abstract": "A cadmium-thiocyanate complex, poly[[bis(nicotinic acid-\u03baN)di-\u03bc-thiocyanato-\u03ba<sup>2</sup> N:S;\u03ba<sup>2</sup> S:N-cadmium(II)] monohydrate], {[Cd(NCS)<inf>2</inf>(C<inf>6</inf>H5NO2)<inf>2</inf>] H<inf>2</inf>O} n , was synthesized by the reaction of nicotinic acid, cadmium nitrate tetrahydrate and potassium thiocyanide in aqueous solution. In the crystal structure, each Cd<sup>II</sup> cation is in a distorted octahedral coordination environment, coordinated by the N and S atoms of nicotinic acid and thiocyanate ligands. Neighbouring Cd<sup>II</sup> cations are linked together by thiocyanate bridges to form a two-dimensional network. Hydrogen-bond interactions between the uncoordinated solvent water molecules and the organic ligands result in the formation of the three-dimensional supramolecular network.",
        "keywords": [
            "cadmium(II)",
            "crystal structure",
            "hydrogen bonding",
            "nicotinic acid",
            "thiocyanate",
            "two-dimensional coordination polymer"
        ],
        "venue": "Acta Crystallographica Section C: Structural Chemistry",
        "year": 2015,
        "id": "tBzo9meK"
    },
    "sM6ciaoN": {
        "authors": [
            {
                "name": "Hui-Ting Wang",
                "org": "Ordered Matter Science Research Center"
            },
            {
                "name": "Qiang Li",
                "org": "Ordered Matter Science Research Center"
            },
            {
                "name": "Ping-Ping Shi",
                "org": "Ordered Matter Science Research Center"
            },
            {
                "name": "Lin Zhou",
                "org": "Ordered Matter Science Research Center"
            },
            {
                "name": "Yi Zhang",
                "org": "Ordered Matter Science Research Center"
            },
            {
                "name": "Qiong Ye",
                "org": "Ordered Matter Science Research Center"
            },
            {
                "name": "Da-Wei Fu",
                "org": "Ordered Matter Science Research Center"
            }
        ],
        "title": "The structures and dielectric properties of high temperature phase transition compounds with 4-(dimethylamino)pyridinium",
        "abstract": "The reactions of 4-(dimethylamino)pyridine (DMAP) and metal chloride in dilute hydrochloric acid yield two four-coordinate complexes, 1 (DMAP",
        "keywords": [
            "Dielectric",
            "Differential scanning calorimetry",
            "Order-disorder",
            "Orientational changes",
            "Phase transition",
            "Variable-temperature X-ray"
        ],
        "venue": "Inorganic Chemistry Communications",
        "year": 2015,
        "id": "sM6ciaoN"
    },
    "LK3yYs7R": {
        "authors": [
            {
                "name": "Xing-Rong Peng",
                "org": "Graduate University of the Chinese Academy of Sciences"
            },
            {
                "name": "Xia Wang",
                "org": "Graduate University of the Chinese Academy of Sciences"
            },
            {
                "name": "Lin Zhou",
                "org": "Graduate University of the Chinese Academy of Sciences"
            },
            {
                "name": "Bo Hou",
                "org": "Graduate University of the Chinese Academy of Sciences"
            },
            {
                "name": "Zhi-Li Zuo",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Ming-Hua Qiu",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            }
        ],
        "title": "Ganocochlearic acid A, a rearranged hexanorlanostane triterpenoid, and cytotoxic triterpenoids from the fruiting bodies of Ganoderma cochlear",
        "abstract": "Ganocochlearic acid A (1), a rearranged hexanorlanostane triterpenoid featuring a \u03b3-lactone ring and a five-membered carbon ring, and eleven new lanostane triterpenoids (2-12), along with six known analogues (13-18) were isolated from the fruiting bodies of Ganoderma cochlear. Their structures, including absolute configurations, were established on the basis of the MS, NMR, X-ray crystallographic, and ECD analysis. A plausible biosynthetic pathway for 1 was proposed. Compounds 7-9, 11-13 showed moderate cytotoxic activities against five human tumor cell lines (HL-60, SMMC-7721, A-549, MCF-7 and SW480) with IC",
        "keywords": [
            ""
        ],
        "venue": "RSC Advances",
        "year": 2015,
        "id": "LK3yYs7R"
    },
    "hFsdLdUh": {
        "authors": [
            {
                "name": "Jian-Chao Chen",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences"
            },
            {
                "name": "Clara Bik-San Lau",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China (CUHK)"
            },
            {
                "name": "Judy Yuet-Wa Chan",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China (CUHK)"
            },
            {
                "name": "Kwok-Pui Fung",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China (CUHK)"
            },
            {
                "name": "Ping-Chung Leung",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China (CUHK)"
            },
            {
                "name": "Jie-Qing Liu",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences"
            },
            {
                "name": "Ming-Jin Xie",
                "org": "School of Chemical Science and Technology, Yunnan University"
            },
            {
                "name": "Ming-Hua Qiu",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences"
            }
        ],
        "title": "The antigluconeogenic activity of cucurbitacins from Momordica charantia",
        "abstract": "Five new cucurbitacins, kuguacins II-VI (1-5), along with five known analogues (6-10), were obtained from the fruit of Momordica charantia. Structures of the new compounds were elucidated as 5\u03b2,19-epoxycucurbit-23-en-7-on-3\u03b2,25-diol (1), 5\u03b2,19-epoxycucurbit-7,23-dion-3\u03b2,25-diol (2), 5\u03b2,19-epoxycucurbit-6-en-19,23-dion-3\u03b2,25-diol (3), 5\u03b2,19-epoxy-23,24,25,26,27-pentanorcucurbit-6-en-7,19-dion-3\u03b2,22-diol (4), and cucurbit-5-en-7,23-dion-3\u03b2,19,25-triol (5) by extensive spectroscopic and single-crystal X-ray diffraction analyses. Some cucurbitane compounds from this species were screened for their potential antidiabetic properties in terms of antigluconeogenic activity. As a result, compounds 1, 10, 11, and 12 (at 25-100 \u03bcM) showed concentration-dependent inhibition on glucose production from liver cells. In addition, compounds 11 and 12 (at 100 \u03bcM) showed around 20-30% inhibition on PEPCK activity.",
        "keywords": [
            "antigluconeogenic activity",
            "Cucurbitaceae",
            "cucurbitacin",
            "kuguacins II-VI",
            "Momordica charantia",
            "PEPCK activity"
        ],
        "venue": "Planta Medica",
        "year": 2015,
        "id": "hFsdLdUh"
    },
    "r8rPRTAc": {
        "authors": [
            {
                "name": "Xingrong Peng",
                "org": "Graduate University, Chinese Academy of Sciences"
            },
            {
                "name": "Jieqing Liu",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences"
            },
            {
                "name": "Cuifang Wang",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences"
            },
            {
                "name": "Zhonghui Han",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences"
            },
            {
                "name": "Yi Shu",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences"
            },
            {
                "name": "Xuyang Li",
                "org": "Graduate University, Chinese Academy of Sciences"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences"
            },
            {
                "name": "Minghua Qiu",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences"
            }
        ],
        "title": "Unusual prenylated phenols with antioxidant activities from Ganoderma cochlear",
        "abstract": "Seven new prenylated phenols, five novel phenols (1-5) with polycyclic skeleton and two new phenols (6 and 7) with a carbon chain, along with one known compound (8) were isolated from the fruiting bodies of Ganoderma cochlear. The structures of new compounds were elucidated by the spectroscopic technologies, X-ray crystallography analysis and chiral HPLC chromatography. All compounds showed antioxidant effect in radical scavenging assays and a plausible biosynthetic pathway for 1-8 was proposed.",
        "keywords": [
            "Antioxidant activity",
            "Chiral HPLC chromatography",
            "Ganoderma cochlear",
            "Prenylated phenols",
            "X-ray crystallography analysis"
        ],
        "venue": "Food Chemistry",
        "year": 2015,
        "id": "r8rPRTAc"
    },
    "oJXDWRmu": {
        "authors": [
            {
                "name": "Yu-Xin Yan",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Jie-Qing Liu",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Hong-Wei Wang",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Jin-Xiong Chen",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Jian-Chao Chen",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Li Chen",
                "org": "Institute of Zoology"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            },
            {
                "name": "Ming-Hua Qiu",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China"
            }
        ],
        "title": "Identification and Antifeedant Activities of Limonoids from Azadirachta indica",
        "abstract": "Four new limonoids, azadiraindins A-D (1-4, resp.), together with seven known analogs, were isolated from the MeOH extract of Azadirachta indica. The structures of 1-4 were elucidated by NMR and MS spectroscopic analyses, and the relative configuration of 1 was determined by single-crystal X-ray crystallography. The compounds isolated in comparatively large amount were evaluated for their antifeedant activities against Plutella xylostella; the antifeedant rate of 10 was 90.6% and the corrected mortality of 8 was 79.2%.",
        "keywords": [
            "Antifeedants",
            "Azadirachta indica",
            "Azadiraindins A - D",
            "Limonoids"
        ],
        "venue": "Chemistry and Biodiversity",
        "year": 2015,
        "id": "oJXDWRmu"
    },
    "Z2aNSjpS": {
        "authors": [
            {
                "name": "JieQing Liu",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Science"
            },
            {
                "name": "YuanFeng Yang",
                "org": "Graduate University, Chinese Academy of Science"
            },
            {
                "name": "JianJun Xia",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Science"
            },
            {
                "name": "XuYang Li",
                "org": "Graduate University, Chinese Academy of Science"
            },
            {
                "name": "ZhongRong Li",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Science"
            },
            {
                "name": "Lin Zhou",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Science"
            },
            {
                "name": "MingHua Qiu",
                "org": "State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Science"
            }
        ],
        "title": "Cytotoxic diterpenoids from Jatropha curcas cv. nigroviensrugosus CY Yang Roots",
        "abstract": "Abstract An investigation of phytochemicals from the roots of Jatropha curcas cv. nigroviensrugosus resulted in the isolation of twenty diterpenoids, including lathyranlactone, an unusual diterpenoid lactone possessing a 5/13/3 tricyclic skeleton, jatrocurcasenones A-E and jatrophodiones B-E, as well as 10 known analogues. All isolates were evaluated for cytotoxicity against the HL-60, SMMC-772, A-549, MCF-7 and SW480 human tumor cell lines using the MTS viability assay. Four of the known analogues showed cytotoxic activity in these cell lines, with IC<inf>50</inf> values ranging from 2.0 to 23.0 \u03bcM. Moreover, the assessment of their cytotoxic structure-activity relationships showed the epoxy ring between C-5 and C-6 and the hydroxyl group at C-2 were the key functionalities for cytotoxicity.",
        "keywords": [
            "Cytotoxic activity",
            "Diterpenoids",
            "Euphorbiaceae",
            "Jatropha curcas"
        ],
        "venue": "Phytochemistry",
        "year": 2015,
        "id": "Z2aNSjpS"
    },
    "H79qYqGH": {
        "authors": [
            {
                "name": "Zhen-Jie Li",
                "org": ""
            },
            {
                "name": "Jian-Chao Chen",
                "org": ""
            },
            {
                "name": "Yuan-Yuan Deng",
                "org": ""
            },
            {
                "name": "Na-Li Song",
                "org": ""
            },
            {
                "name": "Mu-Yuan Yu",
                "org": ""
            },
            {
                "name": "Lin Zhou",
                "org": ""
            },
            {
                "name": "Ming-Hua Qiu",
                "org": ""
            }
        ],
        "title": "Two New Cucurbitane Triterpenoids from Immature Fruits of Momordica charantia",
        "abstract": "Two new cucurbitane triterpenoids, kuguacin X (1) and kuguaglycoside I (2), together with three known analogs, were isolated from immature fruits of Momordica charantia. By detailed analysis of IR, NMR, and MS data, acid hydrolysis, and comparison with spectroscopic data of known compounds, the new compounds were determined to be (23E)-5\u03b2,19-epoxycucurbita-6,23-diene-3\u03b2,22\u03be,25-triol (1) and (23E)-5\u03b2,19-epoxycucurbita-6,23-dien-19-on-3\u03b2,25-diol 3-O-\u03b2-D-allopyranoside (2).",
        "keywords": [
            "Cucurbitane triterpenoids",
            "Kuguacin X",
            "Kuguaglycoside I",
            "Momordica charantia"
        ],
        "venue": "Helvetica Chimica Acta",
        "year": 2015,
        "id": "H79qYqGH"
    },
    "ZHbnOEmC": {
        "authors": [
            {
                "name": "Jun-Jun Jia",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Jian-Hui Li",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Li Jiang",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Bin-Yi Lin",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Li Wang",
                "org": "Key Laboratory of Combined Multi-organ Transplantation"
            },
            {
                "name": "Rong Su",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Lin Zhou",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Department of Hepatobiliary and Pancreatic Surgery"
            }
        ],
        "title": "Liver protection strategies in liver transplantation",
        "abstract": "Background Liver transplantation is the therapy of choice for patients with end-stage liver diseases. However, the gap between the low availability of organs and high demand is continuously increasing. Innovative strategies for organ protection are necessary to expand donor pool and to achieve better outcomes for liver transplantation. The present review analyzed and compared various strategies of liver protection. Data sources Databases such as PubMed, Embase and Ovid were searched for the literature related to donor liver protection strategies using following key words: \"ischemia reperfusion injury\", \"graft preservation\", \"liver transplantation\", \"machine perfusion\" and \"conditioning\". Of the 146 studies identified, only those with cutting edge strategies were analyzed. Results A variety of therapeutic approaches were proposed to alleviate graft ischemia/reperfusion injury, which included static cold storage, machine perfusion (hypothermic, normothermic and subnormothermic), manual conditioning (pre, post and remote), and pharmacological conditioning. Evidences from animal experiments and clinical trials suggested that all these strategies could potentially protect liver graft; however, their clinical applications are limited partially due to their own disadvantages. Conclusions There are a plenty of methods suggested to decrease the degree of donor liver transplantation-related injury. However, none of these approaches is perfect in clinical practice. More translational researches (molecular and clinical studies) are needed to improve the techniques in liver graft protection.",
        "keywords": [
            "conditioning",
            "ischemia reperfusion injury",
            "liver transplantation",
            "organ protection"
        ],
        "venue": "Hepatobiliary and Pancreatic Diseases International",
        "year": 2015,
        "id": "ZHbnOEmC"
    },
    "XegibzcX": {
        "authors": [
            {
                "name": "Bing-Yi Lin",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation, Ministry of Public Health, Zhejiang University"
            },
            {
                "name": "Lin Zhou",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Zhejiang University"
            },
            {
                "name": "Lei Geng",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Zhejiang University"
            },
            {
                "name": "Zhi-Yun Zheng",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation, Ministry of Public Health, Zhejiang University"
            },
            {
                "name": "Jun-Jun Jia",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation, Ministry of Public Health, Zhejiang University"
            },
            {
                "name": "Jing Zhang",
                "org": "Key Laboratory of Combined Multi-Organ Transplantation, Ministry of Public Health, Zhejiang University"
            },
            {
                "name": "Jia Yao",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Zhejiang University"
            },
            {
                "name": "Shu-Sen Zheng",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Zhejiang University"
            }
        ],
        "title": "High neutrophil-lymphocyte ratio indicates poor prognosis for acute-on-chronic liver failure after liver transplantation",
        "abstract": "AIM: To investigate the significance of pre-transplant neutrophil-lymphocyte ratio (NLR) in determining the prognosis of liver transplant (LT) recipients with acuteonchronic liver failure (ACLF). METHODS: Data were collected from the liver transplantation data bank. The NLR values and other conventional inflammatory markers were evaluated for their ability to predict the prognosis of 153 patients with ACLF after LT. The NLR cut-off value was based on a receiver operating characteristic curve analysis. A Kaplan-Meier curve analysis and univariate and multivariate Cox regression models were used to define the independent risk factors for poor outcomes. RESULTS: The optimal NLR cut-off value was 4.6. Out of 153 patients, 83 (54.2%) had an NLR \u2265 4.6. The 1-, 3-, and 5-year overall survival rates were 94.3%, 92.5% and 92.5%, respectively, in the normal NLR group and 74.7%, 71.8% and 69.8%, respectively, in patients with high NLRs (P < 0.001). Furthermore, there was a significant difference in infectious complications after LT between the high and normal NLR groups. There were no significant differences for other complications. In the multivariate Cox regression model, a high NLR was defined as a significant predictor of poor outcomes for LT. CONCLUSION: A high NLR is a convenient and available predictor for prognosis of LT patients and can potentially optimize the current criteria for LT in ACLF.",
        "keywords": [
            "Acute liver failure",
            "Acute-on-chronic liver failure",
            "Inflammation",
            "Liver transplantation",
            "Neutrophil-lymphocyte ratio"
        ],
        "venue": "World Journal of Gastroenterology",
        "year": 2015,
        "id": "XegibzcX"
    },
    "NBAdvo0b": {
        "authors": [
            {
                "name": "Zhenhua Hu",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Qijun Zhang",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Jie Zhou",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Zhiwei Li",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Jie Xiang",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Lin Zhou",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Jian Wu",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Min Zhang",
                "org": "Key Laboratory of Organ Transplantation"
            },
            {
                "name": "Shusen Zheng",
                "org": "Key Laboratory of Organ Transplantation"
            }
        ],
        "title": "Impact of multiple liver resections prior to salvage liver transplantation on survival in patients with recurrent HCC",
        "keywords": [
            ""
        ],
        "venue": "BMJ Open",
        "year": 2015,
        "id": "NBAdvo0b"
    },
    "Z0yRx3cN": {
        "authors": [
            {
                "name": "Zhengtao Liu",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, School of Medicine, Zhejiang University"
            },
            {
                "name": "Shuping Que",
                "org": "Department of Pediatrics, Women and Children's Hospital of Guangxi"
            },
            {
                "name": "Lin Zhou",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, School of Medicine, Zhejiang University"
            },
            {
                "name": "Shusen Zheng",
                "org": "Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, School of Medicine, Zhejiang University"
            }
        ],
        "title": "Dose-response Relationship of Serum Uric Acid with Metabolic Syndrome and Non-alcoholic Fatty Liver Disease Incidence: A Meta-analysis of Prospective Studies",
        "abstract": "Emerging evidence has shown that serum uric acid (SUA) elevation might cause metabolic derangements, including metabolic syndrome (MetS) and non-alcoholic fatty liver disease (NAFLD); however, magnitude of the risk has not been quantified. We searched PubMed, EMBASE, and ISI databases for relevant studies through 10 May 2015. Prospective studies reporting the risk of SUA elevation on the incidence of MetS/NAFLD were enrolled. Pooled HR of MetS was 1.55 (95%CI: 1.40-1.70) for the highest versus lowest SUA categories, and 1.05 (95%CI: 1.04-1.07) per incremental increased in SUA of 1 \u20ac\u2030mg/dl. The pooled HR of MetS in younger women was higher than age-matched men and older women (1.17 vs. 1.05 and 1.04, respectively, P \u20ac\u2030< \u20ac\u20300.05). Individuals in the highest SUA category had a 40% greater risk of disease NAFLD occurrence. Dose-response increment of NAFLD events was 1.03 (95%CI: 1.02-1.05). A positive relationship with a linear trend for SUA elevation with MetS and NAFLD in different genders was examined by a dose-response meta-analysis (P \u20ac\u2030< \u20ac\u20300.001).SUA assay is useful in screening metabolic disorders for linear trend between its elevation and MetS/NAFLD incidence. SUA-lowering therapy is a potential strategy for preventing systemic/hepatic metabolic abnormalities.",
        "keywords": [
            ""
        ],
        "venue": "Scientific Reports",
        "year": 2015,
        "id": "Z0yRx3cN"
    },
    "K0RLR9R8": {
        "authors": [
            {
                "name": "Xinhua Chen",
                "org": "Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases"
            },
            {
                "name": "Zhigang Ren",
                "org": "Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases"
            },
            {
                "name": "Tongyin Zhu",
                "org": "Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases"
            },
            {
                "name": "Xiongxin Zhang",
                "org": "Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases"
            },
            {
                "name": "Zhiyi Peng",
                "org": "Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases"
            },
            {
                "name": "Haiyang Xie",
                "org": "Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases"
            },
            {
                "name": "Lin Zhou",
                "org": "Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases"
            },
            {
                "name": "Shengyong Yin",
                "org": "Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases"
            },
            {
                "name": "Junhui Sun",
                "org": "Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases"
            },
            {
                "name": "Shusen Zheng",
                "org": "Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases"
            }
        ],
        "title": "Electric Ablation with Irreversible Electroporation (IRE) in Vital Hepatic Structures and Follow-up Investigation",
        "abstract": "Irreversible electroporation (IRE) with microsecond-pulsed electric fields (\u03bcsPEFs) can effectively ablate hepatocellular carcinomas in animal models. This preclinical study evaluates the feasibility and safety of IRE on porcine livers. Altogether, 10 pigs were included. Computed tomography (CT) was used to guide two-needle electrodes that were inserted near the hilus hepatis and gall bladder. Animals were followed-up at 2 hours and at 2, 7 and 14 days post-treatment. During and after \u03bcsPEF ablation, electrocardiographs found no cardiovascular events, and contrast CT found no portal vein thrombosis. There was necrosis in the ablation zone. Mild cystic oedema around the gall bladder was found 2 hours post-treatment. Pathological studies showed extensive cell death. There was no large vessel damage, but there was mild endothelial damage in some small vessels. Follow-up liver function tests and routine blood tests showed immediate liver function damage and recovery from the damage, which correlated to the pathological changes. These results indicate that \u03bcsPEF ablation affects liver tissue and is less effective in vessels, which enable \u03bcsPEFs to ablate central tumour lesions close to the hilus hepatis and near large vessels and bile ducts, removing some of the limitations and contraindications of conventional thermal ablation.",
        "keywords": [
            ""
        ],
        "venue": "Scientific Reports",
        "year": 2015,
        "id": "K0RLR9R8"
    },
    "17kWEuQy": {
        "id": "17kWEuQy",
        "title": "Three-dimensional pin power reconstruction for the axially heterogeneous region in BWR",
        "abstract": "A three-dimensional pin power reconstruction method was proposed and verified by applying to the axially heterogeneous region problem of the BWR core calculation. Because the production assembly calculation has been carried out by two-dimensional deterministic calculation methods like current coupling collision probability or the method of characteristics, it has been difficult to predict the detailed three-dimensional heterogeneous pin power distribution of the axially heterogeneous region. Consequently, only radial intranodal homogeneous power distributions have been considered, and axial intranodal homogeneous power distributions have not been considered in the estimation of linear-heat-generation-ratio at common BWR core calculations. For an axially heterogeneous region in which two different nodes are combined, the Monte Carlo calculation method can execute three-dimensional heterogeneous assembly calculation directly. By taking advantage of this point, we proposed a three-dimensional pin power reconstruction method. The present three-dimensional pin power reconstruction method was applied to the control-rod-tip (CRT) region problem in BWR. The validity of this method was verified from the result obtained, in which the relative bundle-averaged three-dimensional pin power distribution was improved about 5% of RMS over without three-dimensional pin power reconstruction method.",
        "keywords": [
            "method of characteristics",
            "three dimensional",
            "monte carlo"
        ],
        "authors": [
            {
                "name": "Masayuki Tohjoh",
                "org": ""
            },
            {
                "name": "Masato Watanabe",
                "org": "Chubu Electric Power Co., Inc., 20-1 Kitasekiyama, Odaka-cho, Midori-ku, Nagoya, 459-8522, Japan"
            },
            {
                "name": "Akio Yamamoto",
                "org": "Department of Material Physics and Energy Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan"
            }
        ],
        "venue": "Annals of Nuclear Energy",
        "year": 2006
    },
    "P3sSYOLN": {
        "id": "P3sSYOLN",
        "title": "Validation of neutron current formulations for the response matrix method based on the SP3 theory",
        "abstract": "The pin-by-pin fine mesh BWR core analysis code SUBARU has been developed as a next-generation BWR core analysis code. SUBARU is based on the SP3 theory and the response matrix method is used for flux calculations. The SP3 theory consists of the 0th and 2nd order neutron fluxes. Therefore, the relations among the 0th and 2nd order partial neutron currents and the fluxes are required to apply the response matrix method. SUBARU is approximated the relations among the partial neutron currents and the fluxes are similar to that the diffusion theory. Our previous study revealed that the prediction accuracy of SUBARU is much higher than that of conventional core analysis codes. However, validity of the above approximation is not directly investigated so far. Therefore, relations among the partial neutron currents and the fluxes are theoretically derived and calculation results with the rigorous and the conventional formulations are compared. The calculation results indicate that the approximation of the conventional formulation is appropriate for the BWR core analysis.",
        "keywords": [],
        "authors": [
            {
                "name": "Kenichi Tada",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": "Department of Materials, Physics and Energy Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan"
            },
            {
                "name": "Yoshihiro Yamane",
                "org": "Department of Materials, Physics and Energy Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan"
            },
            {
                "name": "Shinya Kosaka",
                "org": "TEPCOSYSTEMS CORPORATION, 2-37-28, Eitai, Koto-ku, Tokyo 135-0034, Japan"
            },
            {
                "name": "Gou Hirano",
                "org": "TEPCOSYSTEMS CORPORATION, 2-37-28, Eitai, Koto-ku, Tokyo 135-0034, Japan"
            }
        ],
        "venue": "Annals of Nuclear Energy",
        "year": 2010
    },
    "xSBHDclZ": {
        "id": "xSBHDclZ",
        "title": "Measuring the Ratio of 242Cm to 244Cm in Operating BWR Cores Using Start-Up Range Neutron Monitors",
        "abstract": "",
        "keywords": [
            "prediction error",
            "least square method",
            "time series",
            "neutron source"
        ],
        "authors": [
            {
                "name": "Masato WATANABE",
                "org": ""
            },
            {
                "name": "Akio YAMAMOTO",
                "org": ""
            },
            {
                "name": "Yoshihiro YAMANE",
                "org": ""
            }
        ],
        "venue": "Journal of Nuclear Science and Technology",
        "year": 2008
    },
    "wdKqqfJR": {
        "id": "wdKqqfJR",
        "title": "Development of deterministic code based on the discrete ordinates method for the third-order neutron correlation technique",
        "abstract": "The third-order neutron correlation technique is one of the subcriticality measurement techniques. The significant feature of this technique is that an absolute value of subcriticality can be evaluated from the measured neutron correlation factors, namely Y \u221e and X \u221e . In order to extend the applicability of the third-order neutron correlation technique to actual complicated subcritical systems, we previously derived the spatial and neutron energy dependent theoretical formulas of Y \u221e and X \u221e by using the first-, second-, and third-order importance functions. These theoretical formulas depend on the locations of both an external neutron source and a neutron detector. The numerical solutions of these formulas are very useful to design the arrangements of the external neutron source and the neutron detector and to investigate the contamination of the spatial effect in the measured neutron correlation factors, Y \u221e and X \u221e . Therefore, we developed a novel deterministic code that can calculate both Y \u221e and X \u221e based on the S N method. In this paper, we focus on the description of the numerical procedure of this code and its verification by comparing it with the results of Monte Carlo simulations.",
        "keywords": [
            "monte carlo simulation"
        ],
        "authors": [
            {
                "name": "Tomohiro Endo",
                "org": "Department of Materials, Physics and Energy Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan"
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Yoshihiro Yamane",
                "org": "Department of Materials, Physics and Energy Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan"
            }
        ],
        "venue": "Annals of Nuclear Energy",
        "year": 2008
    },
    "lJ3EIhrA": {
        "id": "lJ3EIhrA",
        "title": "Application of Nodal Method to Lambda Mode Higher Harmonics Code.",
        "abstract": "",
        "keywords": [
            "finite difference method",
            "eigenvalues",
            "finite element method"
        ],
        "authors": [
            {
                "name": "Tsuyoshi MISAWA",
                "org": ""
            },
            {
                "name": "Akio YAMAMOTO",
                "org": ""
            },
            {
                "name": "Yoshihiro YAMANE",
                "org": ""
            }
        ],
        "venue": "Journal of Nuclear Science and Technology",
        "year": 1996
    },
    "DjpAO8f2": {
        "id": "DjpAO8f2",
        "title": "Treatment of Staggered Mesh for BWR Pin-by-Pin Core Analysis",
        "abstract": "",
        "keywords": [
            "method of characteristics"
        ],
        "authors": [
            {
                "name": "Kenichi TADA",
                "org": ""
            },
            {
                "name": "Akio YAMAMOTO",
                "org": ""
            },
            {
                "name": "Yoshihiro YAMANE",
                "org": ""
            }
        ],
        "venue": "Journal of Nuclear Science and Technology",
        "year": 2009
    },
    "XT1QJTYk": {
        "id": "XT1QJTYk",
        "title": "Detected-neutron multiplication factor measured by neutron source multiplication method",
        "abstract": "An alternative definition of neutron multiplication factor measured by the neutron source multiplication (NSM) method is newly proposed. This newly defined neutron multiplication factor, k det , is derived on the basis of neutron detection process in a subcritical system with an external neutron source. The definition of k det is expressed as a ratio of total number of detected fission-neutrons to total number of detected all neutrons . In this paper, a heuristic derivation of k det is presented, and another interpretation of k det is explained by using the detector importance function. Based on the idea of k det , the measurement principle of NSM method is reinterpreted, and the correction factors in the NSM method are clarified. In order to verify our proposed NSM method, numerical analysis of the NSM method is carried out. The numerical results suggest that target neutron multiplication factors of the NSM method can be well estimated even without any corrections by putting a neutron detector where the effective neutron multiplication factor k eff is well approximated by k det .",
        "keywords": [
            "subcriticality",
            "detected-neutron multiplication factor",
            "neutron source multiplication method",
            "effective neutron multiplication factor",
            "detector importance",
            "numerical analysis"
        ],
        "authors": [
            {
                "name": "Tomohiro Endo",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": "Department of Materials, Physics and Energy Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan"
            },
            {
                "name": "Yoshihiro Yamane",
                "org": "Department of Materials, Physics and Energy Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan"
            }
        ],
        "venue": "Annals of Nuclear Energy",
        "year": 2011
    },
    "oJqdni8J": {
        "id": "oJqdni8J",
        "title": "Measuring the Photoneutrons Originating from D(\u03b3, n)H Reaction after the Shutdown of an Operational BWR",
        "abstract": "",
        "keywords": [
            "cm",
            "neutron source",
            "least square method",
            "gamma ray",
            "fission product"
        ],
        "authors": [
            {
                "name": "Masato WATANABE",
                "org": ""
            },
            {
                "name": "Akio YAMAMOTO",
                "org": ""
            },
            {
                "name": "Yoshihiro YAMANE",
                "org": ""
            }
        ],
        "venue": "Journal of Nuclear Science and Technology",
        "year": 2009
    },
    "6GFYozCi": {
        "id": "6GFYozCi",
        "title": "Cell homogenization methods for pin-by-pin core calculations tested in slab geometry",
        "abstract": "In this paper, performances of spatial homogenization methods for fuel or non-fuel cells are compared in slab geometry in order to facilitate pin-by-pin core calculations. Since the spatial homogenization methods were mainly developed for fuel assemblies, systematic study of their performance for the cell-level homogenization has not been carried out. Importance of cell-level homogenization is recently increasing since the pin-by-pin mesh core calculation in actual three-dimensional geometry, which is less approximate approach than current advanced nodal method, is getting feasible. Four homogenization methods were investigated in this paper; the flux-volume weighting, the generalized equivalence theory, the superhomogenization (SPH) method and the nonlinear iteration method. The last one, the nonlinear iteration method, was tested as the homogenization method for the first time. The calculations were carried out in simplified colorset assembly configurations of PWR, which are simulated by slab geometries, and homogenization performances were evaluated through comparison with the reference cell-heterogeneous calculations. The calculation results revealed that the generalized equivalence theory showed best performance. Though the nonlinear iteration method can significantly reduce homogenization error, its performance was not as good as that of the generalized equivalence theory. Through comparison of the results obtained by the generalized equivalence theory and the superhomogenization method, important byproduct was obtained; deficiency of the current superhomogenization method, which could be improved by incorporating the \u201ccell-level discontinuity factor between assemblies\u201d, was clarified.",
        "keywords": [
            "three dimensional",
            "iteration method"
        ],
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Yasunori Kitamura",
                "org": "Department of Nuclear Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Japan, 464-8603"
            },
            {
                "name": "Yoshihiro Yamane",
                "org": "Department of Nuclear Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Japan, 464-8603"
            }
        ],
        "venue": "Annals of Nuclear Energy",
        "year": 2004
    },
    "9uF0DzUj": {
        "id": "9uF0DzUj",
        "title": "Development of New Solid Angle Quadrature Sets to Satisfy Even- and Odd-Moment Conditions",
        "abstract": "",
        "keywords": [
            "solid angle",
            "satisfiability",
            "numerical integration",
            "sn",
            "octant"
        ],
        "authors": [
            {
                "name": "Tomohiro ENDO",
                "org": ""
            },
            {
                "name": "Akio YAMAMOTO",
                "org": ""
            }
        ],
        "venue": "Journal of Nuclear Science and Technology",
        "year": 2007
    },
    "waZJ02Ac": {
        "id": "waZJ02Ac",
        "title": "Simplified Treatments of Anisotropic Scattering in LWR Core Calculations",
        "abstract": "",
        "keywords": [
            "cross section",
            "scattering matrix",
            "higher order"
        ],
        "authors": [
            {
                "name": "Akio YAMAMOTO",
                "org": ""
            },
            {
                "name": "Yasunori KITAMURA",
                "org": ""
            },
            {
                "name": "Yoshihiro YAMANE",
                "org": ""
            }
        ],
        "venue": "Journal of Nuclear Science and Technology",
        "year": 2008
    },
    "WlBrZMCE": {
        "id": "WlBrZMCE",
        "title": "Application of variance-to-mean technique to subcriticality monitoring for accelerator-driven subcritical reactor",
        "abstract": "",
        "keywords": [
            "nuclear energy",
            "nuclear science",
            "nuclear technology",
            "nuclear power"
        ],
        "authors": [
            {
                "name": "Yasunori Kitamura",
                "org": ""
            },
            {
                "name": "Koshi Taguchi",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Yoshihiro Yamane",
                "org": ""
            },
            {
                "name": "Tsuyoshi Misawa",
                "org": ""
            },
            {
                "name": "Chihiro Ichihara",
                "org": ""
            },
            {
                "name": "Hiroshi Nakamura",
                "org": ""
            },
            {
                "name": "Hiroyuki Oigawa",
                "org": ""
            }
        ],
        "venue": "International Journal of Nuclear Energy Science and Technology",
        "year": 2006
    },
    "XCqG3ldz": {
        "id": "XCqG3ldz",
        "title": "Effect of error propagation of nuclide number densities on Monte Carlo burn-up calculations",
        "abstract": "As a result of improvements in computer technology, the continuous energy Monte Carlo burn-up calculation has received attention as a good candidate for an assembly calculation method. However, the results of Monte Carlo calculations contain the statistical errors. The results of Monte Carlo burn-up calculations, in particular, include propagated statistical errors through the variance of the nuclide number densities. Therefore, if statistical error alone is evaluated, the errors in Monte Carlo burn-up calculations may be underestimated. To make clear this effect of error propagation on Monte Carlo burn-up calculations, we here proposed an equation that can predict the variance of nuclide number densities after burn-up calculations, and we verified this equation using enormous numbers of the Monte Carlo burn-up calculations by changing only the initial random numbers. We also verified the effect of the number of burn-up calculation points on Monte Carlo burn-up calculations. From these verifications, we estimated the errors in Monte Carlo burn-up calculations including both statistical and propagated errors. Finally, we made clear the effects of error propagation on Monte Carlo burn-up calculations by comparing statistical errors alone versus both statistical and propagated errors. The results revealed that the effects of error propagation on the Monte Carlo burn-up calculations of 8 \u00d7 8 BWR fuel assembly are low up to 60 GWd/t. 1 Introduction The current methods commonly used in commercial BWR core analysis consist of two separate stages: the assembly calculation by a lattice physics code at a first stage, and the core analyses by a three-dimensional neutronic-thermal hydraulic core calculation code using the assembly constants from the first stage. Recently, deterministic theories such as the current coupling collision probability method (e.g., LANCER ( Ikehara et al., 2001 )) or characteristics method (e.g., CASMO ( Edenius et al., 1991 )) have been used to perform assembly calculations. These deterministic lattice codes have enabled high accurate assembly calculation. However, they involve approximations such as space and energy discretizations, and their calculation geometries are limited to two dimensions. On the other hand, a continuous energy Monte Carlo calculation method involves less approximation of energy and geometries. It can treat three-dimensional heterogeneous regions directly. However, the continuous energy Monte Carlo calculation requires an enormous calculation time to obtain highly accurate assembly calculations. Therefore, Monte Carlo calculation methods have been used as reference codes of assembly calculation in the BWR production calculation field. High burn-up fuel assemblies have been developed to reduce the fuel cycle cost. Therefore, recent fuel assembly designs have been further complicated by high 235 U enrichment, high Gd content, and complex shapes in geometry. In these circumstances, coupled with recent advancement in computer performance, the continuous energy Monte Carlo calculation method has garnered attention ( Tohjoh et al., 2005 ) because of its less reliance on approximation. However, Monte Carlo calculation results contain statistical errors. In the case of single-step Monte Carlo calculation, these statistical errors can be estimated from the number of neutron histories. However, the results of Monte Carlo burn-up calculations include propagated statistical errors may arise from the variance of nuclide number densities. Therefore, the errors in Monte Carlo burn-up calculations evaluated solely on the basis of statistical errors may be underestimated. Such propagation errors on the nuclide number densities have been reported ( Takeda et al., 1999 ). In that study, these errors were evaluated by using a burn-up matrix. And in the case of fast reactors, Takeda et al. proposed that these errors are relatively smaller than errors of the cross-section libraries. However, quantitative analysis of propagations of statistical errors on the nuclide number densities has not been carried out in their study. Furthermore, the effects of these propagation errors on the Monte Carlo burn-up calculations have not been studied. To make clear this effect of error propagation on the Monte Carlo burn-up calculations, we here proposed an equation that can predict the variance of the nuclide number densities after burn-up calculations, and we verified this equation from the results of enormous times in Monte Carlo burn-up calculations. To do this, we executed Monte Carlo burn-up calculations 400 times by changing only initial random numbers. We also verified the effect of the number of burn-up calculation points on variance of nuclide number densities. From these verifications, we estimated the errors of the Monte Carlo burn-up calculations, including both statistical and propagated errors, under several different neutron history numbers. Finally, we made clear the effects of error propagation on Monte Carlo burn-up calculations by comparing statistical errors alone versus both statistical and propagated errors. The results showed that the effects of error propagation on Monte Carlo burn-up calculations of an 8 \u00d7 8 BWR fuel assembly are low up to 60 GWd/t. Section 2 describes three case studies on the propagation of errors examined in this paper. Each case has a different object. Section 3 proposes the equations that predict these propagated errors, and we verify these equations by using the results of large numbers of Monte Carlo burn-up calculations with different initial random numbers. Section 4 discusses the effects of the number of burn-up calculations points on the nuclide number densities of the Monte Carlo burn-up calculations. This section also verifies this effect through a comparison of the results of large numbers of burn up calculations between 20 and 40 burn-up calculation points. Section 5 examines the propagated errors of nuclide number densities in the Monte Carlo burn-up calculations of a BWR fuel assembly. It also quantitatively shows the effects of these propagated errors on the results of the Monte Carlo burn-up calculations, which are including the k -infinity, the corner-rod peaking (CRP), and the neutron flux. The concluding remarks are given in Section 6 . 2 Calculation cases and conditions This section describes our approach to this study and the calculation conditions used. We have executed three cases of calculations: Case 1: Burn-up calculations were performed 400 times under the same calculation conditions except for changes in the initial random numbers. There were 20 burn-up calculation points and 20,000 neutron histories per burn-up calculation point. Case 2: Burn-up calculations were performed 400 times under the same calculation conditions except for changes in the initial random numbers. There were 40 burn-up calculation points and 20,000 neutron histories per burn-up calculation point. The only difference between Cases 1 and 2 is the number of burn-up calculation points. Case 3: Burn-up calculations were performed 10 times under the same calculation conditions except for changes in the initial random numbers. There were 20 burn-up calculation points, and the numbers of neutron histories per burn-up calculation point were 20,000, 200,000, and 2,000,000. (The burn-up calculations were totally carried out 30 times in Case 3.) From Case 1, we discuss the mechanism underlying the propagations of errors of nuclides number densities in Section 3 . The reaction rate of Monte Carlo calculation has a normal distribution. These deviations of in reaction rate reflect the number densities through the burn-up calculation with exponential functions. Therefore, the number densities of Monte Carlo burn-up calculations have a \u201clog-normal\u201d distribution after burn-up calculation. From the comparison of the deviation of the nuclide number density between Cases 1 and 2, we will describe the effect of the number of burn-up calculation points on the variance of the nuclide number densities. We will predict that the deviation of nuclide number density with relation to the number of burn-up calculation points. From Case 3, we will discuss the effects of the deviation in nuclide number densities on the results of Monte Carlo burn-up calculations. We will extend the calculation conditions in order to generalize on the effect of deviation in nuclide number densities on the results of the Monte Carlo burn-up calculations verified above from Cases 1 and 2. In Cases 1 and 2, the numbers of neutron histories are very low, only 20,000. In Case 3, we executed three conditions of neutron histories per burn-up calculation point: 20,000, 200,000 and 2,000,000 histories. We verify that the quantitative effects of the propagated error of the nuclide number densities depend on the neutron histories. We used the continuous energy Monte Carlo burn-up calculation code MVP-BURN ( Nakagawa et al., 1990; Mori et al., 1999; Okumura et al., 2000; Nagaya et al., 2005 ). This Monte Carlo burn-up calculation code can execute branch calculations from a base case. Therefore, we have already reported the application of this Monte Carlo burn-up calculation code as a cross-section generator of BWR ( Tohjoh et al., 2005 ). We used JENDL-3.3 ( Shibata et al., 2002 ) as the evaluated nuclear data file. The calculation target is the hot condition of the 8 \u00d7 8 with a wide-water-rod fuel assembly for BWR5. The volume-averaged temperature of the fuel is 610 \u00b0C and the structure of fuel assembly is 286 \u00b0C. The in-channel void fraction is 40%, and a uniform water density distribution was assumed. The burn-up spatial discretized regions of Gd 2 O 3 rods are annularly divided into 8, and the UO 2 rods are not annularly divided. The spatial discretization of burn-up calculation regions is shown in Fig. 1 . The calculation conditions of this study are summarized in Table 1 . The next section describes the mechanism underlying error propagation of the nuclide number densities. 3 Error propagation in the number densities of Monte Carlo burn-up calculation (from Case 1) The number density of nuclides after the burn-up calculation is described as follows when variation of these nuclides were dominated by absorption reactions: (1) N i = N i - 1 exp ( RR i \u0394 t i ) where N i is the number density of nuclides at step i of the burn-up calculation, N i \u2212 1 is that at the previous step, RR i is the absorption reaction rate of the nuclide, and \u0394 t i is the burn-up period of step i . The number density of the previous step can be described as follows: (2) N i = N 0 exp ( RR 1 \u0394 t 1 ) exp ( RR 2 \u0394 t 2 ) \u22ef exp ( RR i - 1 \u0394 t i - 1 ) exp ( RR i \u0394 t i ) (3) N i = N 0 exp ( RR 1 \u0394 t 1 + RR 2 \u0394 t 2 + \u22ef + RR i - 1 \u0394 t i - 1 + RR i \u0394 t i ) (4) ln N i N 0 = \u2211 i ( RR i \u0394 t i ) where N 0 is the initial number density of the nuclide. We assume that there is a standard deviation s i at the reaction rate of the burn-up calculation step i . Eqs. (1)\u2013(4) can be written as follows: (5) N i \u2032 = N i - 1 \u2032 exp { ( RR i \u00b1 s i ) \u0394 t i } (6) N i \u2032 = N 0 exp { ( RR 1 \u00b1 s 1 ) \u0394 t 1 + ( RR 2 \u00b1 s 2 ) \u0394 t 2 + \u22ef + ( RR i - 1 \u00b1 s i - 1 ) \u0394 t i - 1 + ( RR i \u00b1 s i ) \u0394 t i } (7) N i \u2032 = N 0 exp \u2211 i ( RR i \u0394 t i ) \u00b1 \u2211 i ( s i 2 \u0394 t i 2 ) (8) ln N i \u2032 N 0 = \u2211 i ( RR i \u0394 t i ) \u00b1 \u2211 i ( s i 2 \u0394 t i 2 ) . Substituting Eq. (4) into Eq. (8) , the logarithm of the ratio of the final number density to initial number density, ln N i \u2032 N 0 , can be obtained as follows: (9) ln N i \u2032 N 0 = ln N i N 0 \u00b1 \u2211 i ( s i 2 \u0394 t i 2 ) . Namely, when there is a standard deviation s i at the reaction rate RR i , the logarithm of the ratio of the number density to initial number density, ln N i \u2032 N 0 , has a standard deviation \u2211 i ( s i 2 \u0394 t i 2 ) . In general, a distribution like that shown above, whose logarithm has a standard distribution is called a log-normal distribution. The log-normal distribution has been used in the field of finance. It lacks a symmetrical shape. In the case of decreasing nuclide number densities, the rate of the increase \u2211 i ( RR i \u0394 t i ) is negative; the mode of this log-normal distribution is on the right side. As we mentioned in Section 2 , in Case 1 the distribution of 238 U\u2019s number density at 20 GWd/t is shown in Fig. 2 . Generally, the variance of the log\u2013normal distribution, VAR ( X ), can be written as follows: (10) VAR ( X ) = E ( X 2 ) - { E ( X ) } 2 = exp ( 2 \u03bc + 2 S 2 ) - exp ( 2 \u03bc + S 2 ) = exp ( 2 \u03bc + S 2 ) { exp ( S 2 ) - 1 } where \u03bc is the mean value of the normal distribution after the logarithm transformation of this log\u2013normal distribution and S is the standard deviation of the normal distribution after the transformation. In the case of the normal distribution, we can use a notational system such as A \u00b1 a , where A is the mean value and a is the standard deviation. In this paper, we use the same notations for the log-normal distribution. From Eqs. (9) and (10) , the standard deviation of the rate of the increase (or decrease) of the nuclide number density, N i \u2032 N 0 , after i times of burn-up calculation can be written as (11) N i \u2032 N 0 = N i N 0 \u00b1 VAR = N i N 0 \u00b1 exp 2 \u2211 i ( RR i \u0394 t i ) + \u2211 i ( s i 2 \u0394 t i 2 ) 2 exp \u2211 i ( s i 2 \u0394 t i 2 ) 2 - 1 (12) N i \u2032 N 0 = N i N 0 \u00b1 exp 2 \u2211 i ( RR i \u0394 t i ) + \u2211 i ( s i 2 \u0394 t i 2 ) exp \u2211 i ( s i 2 \u0394 t i 2 ) - 1 (13) N i \u2032 = N i \u00b1 N 0 exp 2 \u2211 i ( RR i \u0394 t i ) + \u2211 i ( s i 2 \u0394 t i 2 ) exp \u2211 i ( s i 2 \u0394 t i 2 ) - 1 Consequently, after i times burn-up calculations, the nuclide number density has the standard deviation N 0 exp 2 \u2211 i ( RR i \u0394 t i ) + \u2211 i ( s i 2 \u0394 t i 2 ) exp \u2211 i ( s i 2 \u0394 t i 2 ) - 1 . This equation can be applied only to the nuclides those decreasing can be written as the absorption reaction of a single nuclide. This would place one log\u2013normal distribution on the other log-normal distributions, if there were several contributions to the generation of the nuclide concerned. However, if there are several components to the reactions of generating concerned nuclide, we cannot grasp the practical errors of these reaction rates separately, especially under the case of the fixed value of burn-up exposures. In the case of fixed value of burn-up exposure, the deviations in the number densities of the fissile nuclides are not in good agreement with Eq. (13) , when analyst input the value of burn-up exposure. This is because the number of fission reactions is controlled by the value of burn-up exposure. For example, when fission rate obtained in Monte Carlo calculation is smaller than mean value due to statistical deviation, exposure time is increased to adjust thermal output (i.e. number of fissions) of current burn-up step; power normalization is carried out in burn-up calculation. The errors in the reaction rates of 235 U and 238 U with 400 burn-up calculations, Case 1, are shown in Fig. 3 . The errors in reaction rate (A), which is statistically evaluated in Monte Carlo calculations, and those in reaction rate (B), calculated from the logarithm of the ratio of number densities, ln N i \u2032 N i - 1 \u2032 , are plotted in Fig. 3 . From this figure, we can observe that the errors of fissile nuclide 235 U, (A) and (B), are not in good agreement. The error of the reaction rate (B) is controlled because the number of the fission reactions is normalized as described above. Therefore, the actual error (B) is lower than the statistical error (A). On the other hand, the errors of 238 U\u2019s (A) and (B) are in good agreement with each other. The results of the relative standard deviations of number density 235 U and 238 U are shown in Fig. 4 . In this figure there are the observed relative standard deviations and the predicted relative standard deviations, which are calculated by the errors of reaction rates (A) and (B). In the case of 238 U of Fig. 4 , the prediction of the relative standard deviation of the number density is in good agreement with the observed for both (A) and (B). On the other hand, in the case of 235 U in Fig. 4 , the predicted relative standard deviation using error (A) is overestimated compared with the observed relative standard deviation because of the normalized number of the fission reactions. This overestimation is large at BOL because of the large contribution of 235 U to the number of fission reactions. The overestimation at BOL is about 10-fold. This is in good agreement with the error in reaction rate shown in Fig. 3 . The predicted relative standard deviation using error (B) is in good agreement with observed relative standard deviations. From Figs. 3 and 4 , we can verify that Eq. (13) is appropriate for the prediction of the relative standard deviation of nuclide number densities, which follow simple burn-up chain like Eq. (1) . 4 Effect of the number of burn-up calculation points on the number densities of Monte Carlo burn-up calculations (from Case 2) In the Monte Carlo burn-up calculations, the errors of reaction rate are transformed into the nuclide number densities through the exponential functions, and these errors are propagated through the burn-up calculations, as we mentioned in Section 3 . In these circumstances, there is a possibility that the errors of the number densities are affected by changes in the number of burn-up calculation points. Generally speaking, the spectrum of neutron energy changes continuously during burn-up calculations. However, we have to execute the burn-up calculation by the discretized calculation point. Therefore, the results of the burn-up calculation would be affected by the choice of burn-up calculation points this is true both for Monte Carlo and deterministic calculations. However, this change in results, i.e. discretization effect of neutron spectrum, is not within the scope of this paper. The question we have to ask here concerns the statistical error of the number densities of the Monte Carlo burn-up calculation. To consider these circumstances, we describe the following problem, called the symmetric random walk model. For example, consider starting the n times random walking from \u201c0\u201d in one dimension. In one random walking, the point can walk + \u03b4 distance with 50% likelihood and it can walk \u2212 \u03b4 distance with 50% likelihood. This problem is called the random walk model; and, because + \u03b4 and \u2212 \u03b4 are equal, the problem is especially called the symmetric random walk model. The range of existence of the point is from \u2212 n\u03b4 to + n\u03b4 after n times random walking. The mean value \u03bc ( n ) and the variance \u03c3 2 ( n ) can be written as follows: (14) \u03bc ( n ) = 0 (15) \u03c3 2 ( n ) = n \u03b4 2 . We will consider that the number of random walkings was changed from n to kn and that the distance was changed from \u03b4 to \u03b4 k . After kn times random walking, the range of existence of the point is unchanged, from \u2212 n\u03b4 to + n\u03b4 , and the mean value is also unchanged, \u03bc ( kn ) = 0. The variance can be written as follows: (16) \u03c3 2 ( kn ) = kn \u03b4 k 2 = 1 k n \u03b4 2 . From Eq. (16) , if the number of burn-up calculation points was multiplied by k , the deviation in nuclide number density would be divided by k . This symmetric random walking model can be applied to the number density of Monte Carlo burn-up calculations. We will verify this effect using results of Case 2. As mentioned in Section 3 , the nuclide number density distribution is, strictly speaking, a log\u2013normal distribution. However, in this section we will demonstrate about the relation of the number of burn-up calculation points and deviation in nuclide number density, using the approximation that the deviation of nuclide number density is in agreement to a normal distribution. The symmetric random walking model can be applied to the distribution of the number density. To verify this point, we execute 400 Monte Carlo burn-up calculations using different initial random numbers; this is called Case 2, as mentioned in Section 2 . In Case 2, the number of burn-up calculation points is 40, twice that in Case 1. The distributions of the 238 U and 244 Cm number densities in Cases 1 and 2 are shown in Figs. 5 and 6 , respectively. From these figures, we can verify that increasing the number of burn-up calculation points broadens the span of the number density distributions. From Fig. 5 , we can also confirm that the mode of the 238 U number density is shifted. It is caused by the fact that the discretized calculation method of burn-up calculation under the spectrum is continuously changing, as we mentioned before. However, this shift is not our target in this paper as described above. The targets of this paper are the deviations of the nuclide number densities. The standard deviations of the 238 U and 244 Cm number densities in Cases 1 and 2 are shown in Figs. 7 and 8 , respectively. The predicted standard deviations from Eq. (16) are shown in these figures. From these figures, we can confirm that the symmetric random-walk model is applicable. The deviation in the number density would be divided by 2 when the number of burn-up calculation points was doubled. In actual Monte Carlo burn-up calculations, the total number of neutron histories dominates the calculation cost. Therefore, we cannot increase the number of burn-up calculation points endlessly; we have to limit the calculation time reasonably. Then, the increase in the number of burn-up calculation points causes a reduction in the neutron number histories of each step in the Monte Carlo calculations. When the neutron histories were multiplied by k , the deviation in k -infinity would be divided by k . On the other hand, when the neutron histories were multiplied by 1/ k , the deviation in the number density would also be multiplied by k . However, the sensitivity of the number densities to k -infinity is lower than that of the number of neutron histories, as described in Section 5 . Therefore, a larger number of neutron histories (a smaller number of burn-up calculation points) is desirable for the analyses, which demand highly accurate results of k -infinity. On the other hand, a smaller number of neutron histories (a larger number of burn-up calculation points) is desirable for the PIE analyses, which demand highly accurate results of the nuclide number densities. 5 Accuracy of the Monte Carlo burn-up calculations including propagated errors of the nuclide number densities (from Case 3) 5.1 Verification of the equations for propagation errors In Section 3 we verified the mechanism underlying the error propagation of nuclide number densities, and in Section 4 we verified the effect of the number of burn-up calculation points on the nuclide number densities. However, the neutron histories of those verifications were very low \u2013 only 20,000 \u2013 because of the large number (400) of executions of burn-up calculations using different initial random numbers. This section verifies that mechanisms and those effects described in previous sections are generally applicable to Monte Carlo burn-up calculations with various number of neutron histories. Furthermore, we will obtain the accuracy of Monte Carlo burn-up calculations on a BWR fuel assembly, including the propagated errors of the nuclide number densities. We executed three sets of calculations, each including 10 burn-up calculations using different initial random numbers. The only different point among three sets is the number of neutron histories: 20,000, 200,000 and 2,000,000. This was Case 3 in Section 2 . In this section, we call the errors of k -infinity, the corner-rod peaking (CRP), and neutron flux, \u201cObserved (Statistical + Propagated)\u201d, which obtained from the statistical analysis of these 10 burn-up calculations. The Observed (Statistical + Propagated) errors include not only statistical errors at particular burn-up point but also those of propagated errors during burn-up calculations. To the contrary, the errors of k -infinity, CRP, and neutron flux evaluated from statistical analysis of Monte Carlo calculations are defined as \u201cCalculated (Statistical)\u201d. The Calculated (Statistical) errors include statistical errors only at particular burn-up point, and they are listed in the output of MVP-BURN. We call the error of nuclides number densities \u201cObserved (Propagated)\u201d, which obtained from the statistical analysis of these 10 burn-up calculations. To the contrary, we call the error of nuclides number densities \u201cPredicted (Propagated)\u201d, which is obtained from Eq. (13) . It is inferred from Sections 3 and 4 that the Observed (Propagated) errors and the Predicted (Propagated) errors of number density are in good agreement. The Observed (Statistical + Propagated) relative standard deviations of k -infinity, corner-rod peaking (CRP), and neutron flux and are shown in Fig. 9 . This figure also shows that the Observed (Propagated) relative standard deviations of the nuclide number densities. The Observed (Propagated) errors of the nuclide number densities depend not only on neutron histories but also on burn-up exposure. On the other hand, the Observed (Statistical + Propagated) errors of k -infinity, CRP, and flux became larger depending only on the neutron histories. Strictly speaking, these Observed (Statistical + Propagated) errors would be large with relation to the burn-up exposure due to the propagation error of number density. However, they do not depend clearly on the burn-up exposures due to the lower effect of the propagation errors than statistical errors. The relative standard deviations of those parameters at the EOL are roughly in agreement with the BOL. This indicates that the errors in those parameters ( k -infinity, peaking factors, and flux) can be predicted in the rough from statistical errors alone due to the low effect of the propagations on these parameters. The errors in the Observed (Statistical + Propagated), Calculated (Statistical) and O/C (Observed (Statistical + Propagated)/Calculated (Statistical)) for k -infinity, flux, and CRP are shown in Fig. 10 . From this figure, we can understand that O/C (Observed (Statistical + Propagated)/Calculated (Statistical)) is roughly 1.0 from BOL to EOL. Nevertheless the propagated errors of nuclide number densities increase as the burn-up exposure increases. The reason why these Observed (Statistical + Propagated) errors do not dependent on burn-up exposure, is that the effect of the propagated errors of nuclides number densities to k -infinity is much lower than the effects of the neutron histories as we mentioned below. Next, we again verify Eq. (13) described in Section 3 . The Observed (Propagated) and the Predicted (Propagated) errors from Eq. (13) of the 235 U and 238 U are shown in Figs. 11 and 12 , respectively. In these figures, the reaction rates were calculated from the logarithm of the ratio of number densities, ln N i \u2032 N i - 1 \u2032 , which were called (B) in Section 3 . From these figures, the errors of the Predicted (Propagated) and Observed (Propagated) are in good agreement. We can consider Eq. (13) reasonable for these nuclides. 5.2 Verification of the effects of propagation errors on Monte Carlo burn-up calculations through sensitivity analyses In this section, we verify the sensitivity of the statistical and propagated errors of the nuclide number density to the results of the Monte Carlo burn-up calculations. As mentioned above, Eq. (13) can predict the errors in the nuclide number densities after burn-up calculations. However, this equation is applicable to the nuclide number densities whose reactions consist of single absorption reactions. In case of the multiple reactions are included in the absorption reactions, and under the fixed burn-up exposure calculations, these errors in number densities are overestimated as in Fig. 4 . Therefore, we use the fitting equations to predict the statistical and propagated errors of the fissile nuclide number densities. The dominant nuclides in the results of k -infinity are major absorption nuclide 238 U and major fissile nuclides 235 U, 239 Pu, and 241 Pu. However, as shown in Fig. 12 , the errors of the number density of 238 U are very low because of its large initial number density. Therefore, we use equations that fit from the total number densities of 235 U, 239 Pu, and 241 Pu. The (Propagated) errors are shown in Fig. 13 . In this figure, we show the equations of the fissile number density fit depend to the burn-up exposures, and several neutron histories. We also show the sensitivity of these fissile nuclides in Fig. 14 . This figures compares the results of the sensitivity analyses of the total number densities of 235 U, 239 Pu, and 241 Pu to the results of k -infinity in the deterministic assembly calculation. The calculation code of this sensitivity analysis is NEUPHYS-C. NEUPHYS-C calculates the effective macroscopic cross sections depending on the collision probability method, and execute the lattice calculation depend on the diffusion theory. The accuracy of this assembly calculation code is verified through the in-core management of the HAMAOKA-2 and 3. From Fig. 14 , we can observe that the sensitivity of the fissile number density to k -infinity is small. The effect of a 0.1% change in fissile number density (e.g., for the 3 wt% UO 2 fuels, this means not 3.3 wt% but 3.003 wt%.) on k -infinity is only about 0.05% \u0394 k . Section 4 showed the effects of the number of burn-up calculation points on nuclide number densities. The deviation in the nuclide number densities would be divided by k if the number of burn-up calculation points was multiplied by k . On the other hand, the number of neutron histories also affects the results for k -infinity. The deviation in k -infinity would be divided by k if the number of neutron histories was multiplied by k . There is a trade-off between the number of the calculation points and the number of neutron histories per burn-up step. However, the sensitivity of the fissile number densities is half that of the neutron histories, as we shown in Fig. 14 . From this figure, we can understand that a larger number of neutron histories (a smaller number of burn-up calculation points) is desirable for the analyses, which demand highly accurate results of k -infinity, as we mentioned in Section 4 . From the errors of the fissile number densities shown in Fig. 13 and the sensitivity of these fissile number densities shown in Fig. 14 , we can predict the dependence of the total statistical and propagated errors on the burn-up exposures. The dependencies of the Statistical + Propagated, Statistical, and (Statistical + Propagated)/(Statistical) errors on the neutron histories are shown in Table 2 and Fig. 15 . From Fig. 10 , we could not observe clearly the effects of the propagations due to the lower effect of the propagations than statistical errors. Actually, Fig. 15 demonstrates that the effect of the Statistical + Propagated errors on the 8 \u00d7 8 BWR assembly is only about 7% that of the MOL (30 GWd/t), due to the quantitative analysis of propagations and statistical errors. This means that the effect of the statistical error propagation of Monte Carlo burn-up calculations is not important to the present BWR fuel assemblies, because the reactivity of the core is dominated by the young fuel bundles like fresh or once-burned fuels. However, for the future high burn-up fuels, such as those exceeding 100 GWd/t, the Monte Carlo burn-up calculation needs to take into consideration the propagated errors through the nuclide number densities. From Figs. 9\u201315 , we can see that the results of k -infinity, CRP, and flux do not depend on the propagation errors. We have also found that the errors of the nuclide number densities depend on the burn-up exposure. To define these errors, the dependence of the accuracy of these parameters on the neutron histories is shown in Fig. 16 . In this figure, the accuracy of each parameter is at 20 GWd/t. The figure shows that we can find the reasonable neutron histories depending on the necessary calculation accuracy without over cost of the Monte Carlo burn-up calculations. 6 Conclusions and recommendations To make clear the effects of error propagations on Monte Carlo burn-up calculations, we studied the mechanism underlying such propagations and we verified this effect quantitatively. First, we proposed an equation that can predict the variance in the nuclide number densities after burn-up calculations, and we verified this equation by performing huge numbers of Monte Carlo burn-up calculations using different initial random numbers. The nuclide number densities of the Monte Carlo burn-up calculations have a log-normal distribution, which is widely used in the field of finance. The proposed equations are applicable to general Monte Carlo burn-up calculations. We also verified the effect of the number of burn-up calculation points on the nuclide number densities. The deviation in the nuclide number densities would be divided by k if the number of calculation points is multiplied by k . This sensitivity is equal to the effect of the neutron histories on k -infinity. However, the sensitivity of the nuclide number density to the results of k -infinity is only half as great as the sensitivity of the neutron histories. Therefore, it is desirable to reduce the number of burn-up calculation points for analyses that require highly accurate estimation of k -infinity. On the other hand, it is desirable to reduce the number of neutron histories for the analyses that require highly accurate of nuclide number densities, like PIE analyses. This effect of the number of calculation points is applicable to the general Monte Carlo burn-up calculations. Finally, based on these verifications, we have estimated the Monte Carlo burn-up calculation errors, including both statistical and propagated errors, by comparing statistical errors alone versus both statistical and propagated errors. These comparisons revealed that the effects of error propagation on the Monte Carlo burn-up calculations of the 8 \u00d7 8 BWR fuel assembly are low up to 60 GWd/t. However, for future high burn-up fuels, such as those exceeding 100 GWd/t, Monte Carlo burn-up calculations must take propagated errors into consideration. Acknowledgements The authors thank T. Yamamoto of Osaka University for his helpful comments on propagation error of number densities. The authors also thank S. Kato, Y. Ito, and H. Yamauchi of Chuden CTI Co., Ltd., for their helpful suggestions on the manuscript. References Edenius et al., 1991 Edenius, M. et al., 1991. The physics model of CASMO-4. In: Proceedings of the International Topical Mtg. Advances in Mathematics, Computations, and Reactor Physics, Pittsburgh, April 28\u2013May 2. Ikehara et al., 2001 Ikehara, T. et al., 2001. Development of BWR fuel assembly nuclear design code LANCER. In: Proceedings of the 2001 Fall Mtg. of the AESJ, I69\u2013I71, in Japanese. Mori et al., 1999 Mori, T., Okumura, K., Nagaya, Y., Nakagawa, M. 1999. Application of continuous energy monte carlo code MVP to burn-up and whole core calculations using cross sections at arbitrary temperatures. In: International Conference on Mathematics and Computer, Reactor Physics and Environmental Analysis in Nuclear Applications (M&C\u201999), Madrid, Spain, September 27\u201330. Nagaya et al., 2005 Nagaya, Y., Mori, T., Okumura, K., Nakagawa, M., 2005. MVP/GMVP II: general purpose Monte Carlo codes for neutron and photon transport calculations based on continuous energy and multigroup methods, JAERI 1348. Nakagawa et al., 1990 Nakagawa, M. et al., 1990. Development of Monte Carlo code for particle transport calculation on vector processor. In: The First International Conference On Supercomputing in Nuclear Applications (SNA\u201990), Mito, Japan, March 12\u201316, Proceeding, 160. Okumura et al., 2000 K. Okumura Validation of a continuous-energy Monte Carlo burn-up code MVP-BURN and its application to analysis of post irradiation experiment J. Nucl. Sci. Technol. 37 2000 128 Shibata et al., 2002 K. Shibata Japanese evaluated nuclear data library version 3 revision-3: JENDL-3.3 J. Nucl. Sci. Technol. 39 2002 1125 Tohjoh et al., 2005 M. Tohjoh M. Watanabe A. Yamamoto Application of continuous-energy Monte Carlo code as a cross-section generator of BWR core calculations Ann. Nucl. Energy 32 8 2005 857 875 Takeda et al., 1999 T. Takeda Estimation of error propagation in Monte Carlo burnup calculations J. Nucl. Sci. Technol. 36 1999 738",
        "keywords": [
            "error propagation",
            "monte carlo"
        ],
        "authors": [
            {
                "name": "Masayuki Tohjoh",
                "org": ""
            },
            {
                "name": "Tomohiro Endo",
                "org": "Department of Material Science and Energy Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan"
            },
            {
                "name": "Masato Watanabe",
                "org": "Chubu Electric Power Co., Inc., 20-1 Kitasekiyama, Odaka-cho, Midori-ku, Nagoya 459-8522, Japan"
            },
            {
                "name": "Akio Yamamoto",
                "org": "Department of Material Science and Energy Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan"
            }
        ],
        "venue": "Annals of Nuclear Energy",
        "year": 2006
    },
    "pk2Kc3Qh": {
        "id": "pk2Kc3Qh",
        "title": "Improvement of the SPH Method for Pin-by-Pin Core Calculations",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Akio YAMAMOTO",
                "org": ""
            },
            {
                "name": "Masahiro TATSUMI",
                "org": ""
            },
            {
                "name": "Yasunori KITAMURA",
                "org": ""
            },
            {
                "name": "Yoshihiro YAMANE",
                "org": ""
            }
        ],
        "venue": "Journal of Nuclear Science and Technology",
        "year": 2004
    },
    "uUHYNVIl": {
        "id": "uUHYNVIl",
        "title": "Approximate Treatment of Thermal Expansion Effect in Lattice Transport Calculations",
        "abstract": "",
        "keywords": [
            "ray tracing",
            "thermal expansion",
            "cross section"
        ],
        "authors": [
            {
                "name": "Akio YAMAMOTO",
                "org": ""
            },
            {
                "name": "Yasunori KITAMURA",
                "org": ""
            },
            {
                "name": "Yoshihiro YAMANE",
                "org": ""
            }
        ],
        "venue": "Journal of Nuclear Science and Technology",
        "year": 2004
    },
    "d2NcjlkK": {
        "id": "d2NcjlkK",
        "title": "Derivation of theoretical formula for the third order neutron correlation technique by using importance function",
        "abstract": "The third order neutron correlation technique is one of the subcriticality measurement techniques. This technique was originally proposed by Furuhashi and utilizes the second and third order neutron correlation factors Y ( T ) and X ( T ), which are evaluated from the variance and third order central moment of neutron counts detected during a counting gate width T , respectively. We can obtain the absolute value of subcriticality from the Y \u221e and X \u221e , which are saturation values of Y ( T ) and X ( T ) when T goes to infinity. In the previous paper, we derived the generalized theoretical formulas of Y \u221e and X \u221e that took account of both the spatial and neutron energy effects. Its derivation was based on a heuristic method in which we consider the branching process of neutron family, and we utilized the \u03b1 -eigenfunction expansion technique. Then, the previous formulas are expressed by multiple sums involving both the \u03b1 -eigenfunctions and their adjoint functions. In this paper, we derive the new compact expressions of Y \u221e and X \u221e by using the importance functions related to the neutron detection process. Present derivation is based on the stochastic equation of neutron transport. New expressions have two advantages. We can clarify the physical meanings of Y \u221e and X \u221e . And, without \u03b1 -eigenfunction expansion, we can calculate Y \u221e and X \u221e directly by calculating the importance functions which satisfy the adjoint neutron transport equations. Moreover, we prove that new expressions of Y \u221e and X \u221e are identical with the previous ones, so that we can conclude that our previous derivation based on a heuristic method is correct.",
        "keywords": [
            "branching process",
            "transport equation",
            "satisfiability"
        ],
        "authors": [
            {
                "name": "Tomohiro Endo",
                "org": ""
            },
            {
                "name": "Yoshihiro Yamane",
                "org": "Department of Materials, Physics and Energy Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan"
            },
            {
                "name": "Akio Yamamoto",
                "org": "Department of Materials, Physics and Energy Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan"
            }
        ],
        "venue": "Annals of Nuclear Energy",
        "year": 2006
    },
    "XioDNFFB": {
        "id": "XioDNFFB",
        "title": "Space and energy dependent theoretical formula for the third order neutron correlation technique",
        "abstract": "We have studied measurement techniques of subcriticality by using the neutron correlation techniques. Among various techniques, we have paid attention to the third order neutron correlation technique, which was proposed by Furuhashi originally and utilizes the third order fluctuations of neutron counts. By using this technique, we can obtain the absolute value of subcriticality with the aid of factorial moments of fission neutron \u03bd and external source neutron q , without prior knowledge of the prompt neutron decay constant at a reference state. However, in order to apply the third order neutron correlation technique to actual experiments, we must consider the spatial and neutron energy effects in this technique. For this purpose, we derived more generalized theoretical formulas of the third order neutron correlation technique that took account of the spatial and neutron energy effects by virtue of the \u03b1 -eigenfunction expansion. Making use of the newly derived formulas, we propose the practical formulas and the experimental procedures based on the fundamental mode approximation.",
        "keywords": [],
        "authors": [
            {
                "name": "Tomohiro Endo",
                "org": ""
            },
            {
                "name": "Yoshihiro Yamane",
                "org": "Department of Materials, Physics and Energy Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan"
            },
            {
                "name": "Akio Yamamoto",
                "org": "Department of Materials, Physics and Energy Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan"
            }
        ],
        "venue": "Annals of Nuclear Energy",
        "year": 2006
    },
    "F2qPtA2h": {
        "id": "F2qPtA2h",
        "title": "An Improved Inverse Analysis Model for Fuel Loading Pattern Optimization",
        "abstract": "",
        "keywords": [
            "diffusion equation",
            "satisfiability",
            "stable matching",
            "higher order"
        ],
        "authors": [
            {
                "name": "Hoai Nam TRAN",
                "org": ""
            },
            {
                "name": "Akio YAMAMOTO",
                "org": ""
            },
            {
                "name": "Yoshihiro YAMANE",
                "org": ""
            }
        ],
        "venue": "Journal of Nuclear Science and Technology",
        "year": 2009
    },
    "JDdFYtcB": {
        "id": "JDdFYtcB",
        "title": "Study of the spatial discretization and temperature distribution approximation effects on BWR assembly calculations",
        "abstract": "The effects of the spatial discretization and temperature distribution approximation on the BWR assembly calculation were studied using the continuous energy Monte Carlo burn-up calculation under several conditions. The radial-division, temperature-distribution, and azimuthal-division effects of a fuel pellet for BWR fuel (8 \u00d7 8, wide-water-rod) were investigated. The calculation results indicate that the effect of the temperature distribution approximation on the assembly calculation is negligible, even if a pin-averaged temperature was assigned to all fuel pins. The effect of the spatial discretization of fuel pellets in the azimuthal direction brings about a 0.15%dk/k prediction error in k -infinity. This effect is caused by the change of the burn-up characteristics in the Gd-rods. Therefore, the azimuthal-division of Gd-rods is desirable to reduce the spatial discretization effect for BWR assembly with higher Gd fuel rods.",
        "keywords": [
            "monte carlo",
            "prediction error"
        ],
        "authors": [
            {
                "name": "Masayuki Tohjoh",
                "org": ""
            },
            {
                "name": "Masato Watanabe",
                "org": "Chubu Electric Power Co., Inc., 20-1 Kitasekiyama, Odaka-cho, Midori-ku, Nagoya, 459-8522, Japan"
            },
            {
                "name": "Akio Yamamoto",
                "org": "Department of Material Science and Energy Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8603, Japan"
            }
        ],
        "venue": "Annals of Nuclear Energy",
        "year": 2006
    },
    "sXCE4GVD": {
        "id": "sXCE4GVD",
        "title": "Application of continuous-energy Monte Carlo code as a cross-section generator of BWR core calculations",
        "abstract": "A continuous-energy Monte Carlo code is newly applied for the assembly calculations of actual BWR core analysis. Few-groups cross-sections and related constants (kinetic parameters) were generated by the continuous-energy Monte Carlo code MVP-BURN, and were tabulated for a core simulator. The commercial BWR, HAMAOKA-3 (1100MWe:BWR-5), was analyzed by a coupled neutronic-thermalhydraulic core simulator based on modified one-group diffusion theory using these assembly constants. The calculated core parameters showed good agreement with the results of the on-line core monitoring system of HAMAOKA-3. Consequently, it was confirmed that the present method is applicable to BWR core production calculations. The present method is a particularly attractive candidate for the analysis of advanced BWR fuel assemblies with exotic geometry and high Gd content, due to the features of the continuous-energy Monte Carlo code, i.e., high accuracy and generalized geometry treatment.",
        "keywords": [
            "monte carlo",
            "cross section"
        ],
        "authors": [
            {
                "name": "Masayuki Tohjoh",
                "org": ""
            },
            {
                "name": "Masato Watanabe",
                "org": "Chubu Electric Power Co., Inc., 20-1 Kitasekiyama, Odaka-cho, Midori-ku, Nagoya 459-8522, Japan"
            },
            {
                "name": "Akio Yamamoto",
                "org": "Department of Material Science and Energy Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan"
            }
        ],
        "venue": "Annals of Nuclear Energy",
        "year": 2005
    },
    "YMQv6iie": {
        "id": "YMQv6iie",
        "title": "Computational efficiencies of approximated exponential functions for transport calculations of the characteristics method",
        "abstract": "In this paper, various approximations of the exponential function are tested from the viewpoint of computational efficiency, i.e. accuracy and computation time. Since considerable part of computation time is devoted to the evaluation of the exponential function in transport calculations using the characteristics method, reduction of its computation time is important. Evaluations of the approximations are carried out on a Linux operating system using two different processors, i.e. Xeon 2.8GHz with 2MB L3 cache and Pentium-III 800 MHz with 512 KB L2 cache. In order to grasp the impact of approximation error of the exponential function on transport calculation results, some sensitivity calculations are executed using the characteristics method. The evaluation results indicate that the table lookup method with linear interpolation or second-order interpolation is computationally efficient for practical calculations.",
        "keywords": [
            "operating system",
            "approximation error",
            "second order",
            "exponential function",
            "linear interpolation"
        ],
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Yasunori Kitamura",
                "org": "Department of Nuclear Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8603, Japan"
            },
            {
                "name": "Yoshihiro Yamane",
                "org": "Department of Nuclear Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8603, Japan"
            }
        ],
        "venue": "Annals of Nuclear Energy",
        "year": 2004
    },
    "6KnPpZDE": {
        "id": "6KnPpZDE",
        "title": "A conceptual design study of proliferation-resistant PWR fuel using reprocessed uranium",
        "abstract": "A conceptual design study was carried out to enhance proliferation-resistant nature of current light water reactor fuels. Main features of the proliferation-resistant fuel design are adoption of alloy instead of oxide and utilization of enriched reprocessed uranium (\u223c10 wt% 235 U). Major dimensions of the fuel assembly were not changed because of thermal-hydraulic considerations and back-fittability to current PWRs. Its smaller 238 U inventory reduces generation of plutonium and 236 U in the reprocessed uranium promotes generation of 238 Pu that has large decay heat. The assembly calculation results of the fuel indicated that the fuel has good proliferation-resistant nature in the viewpoint of decreased plutonium generation, worse plutonium composition and increased decay heat. Neutronic analyses of an equilibrium core loaded with the proliferation-resistant fuels were carried out and calculation results indicate that variations of major core safety parameters are not very large. Therefore, basic feasibility of the proliferation-resistant fuel design using reprocessed uranium was confirmed in the course of this study.",
        "keywords": [
            "conceptual design"
        ],
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Yasuhiro Katagiri",
                "org": ""
            },
            {
                "name": "Yoshihiro Yamane",
                "org": "Department of Nuclear Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan"
            }
        ],
        "venue": "Nuclear Engineering and Design",
        "year": 2005
    },
    "eORDurZj": {
        "id": "eORDurZj",
        "title": "Applicability of the Diffusion and Simplified P3 Theories for Pin-by-Pin Geometry of BWR",
        "abstract": "",
        "keywords": [
            "cross section",
            "method of characteristics"
        ],
        "authors": [
            {
                "name": "Kenichi TADA",
                "org": ""
            },
            {
                "name": "Akio YAMAMOTO",
                "org": ""
            },
            {
                "name": "Yoshihiro YAMANE",
                "org": ""
            },
            {
                "name": "Yasunori KITAMURA",
                "org": ""
            }
        ],
        "venue": "Journal of Nuclear Science and Technology",
        "year": 2008
    },
    "IybWSmq5": {
        "id": "IybWSmq5",
        "title": "Simultaneous Loading Patterns Optimization for Two Successive Cycles of Pressurized Water Reactors",
        "abstract": "",
        "keywords": [
            "objective function",
            "simulated annealing",
            "optimization"
        ],
        "authors": [
            {
                "name": "Akio YAMAMOTO",
                "org": ""
            },
            {
                "name": "Erina SUGIMURA",
                "org": ""
            },
            {
                "name": "Yasunori KITAMURA",
                "org": ""
            },
            {
                "name": "Yoshihiro YAMANE",
                "org": ""
            }
        ],
        "venue": "Journal of Nuclear Science and Technology",
        "year": 2004
    },
    "pP2uwdsU": {
        "id": "pP2uwdsU",
        "title": "Reduction in Workload of BWR In-Core Fuel Shuffling by New Optimization Methods",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Masayuki Toujou",
                "org": ""
            },
            {
                "name": "Kentarou Komori",
                "org": ""
            },
            {
                "name": "Yasunori Kitamura",
                "org": ""
            },
            {
                "name": "Yoshihiro Yamane",
                "org": ""
            }
        ],
        "venue": "Nuclear Technology",
        "year": 2006
    },
    "iWoTLrk7": {
        "id": "iWoTLrk7",
        "title": "Verification of real-time subcriticality measurement based on rossi-alpha method using detection-time acquisition system",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Shinobu Tsubota",
                "org": ""
            },
            {
                "name": "Yoshihiro Yamane",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Yasunori Kitamura",
                "org": ""
            }
        ],
        "venue": "Transactions of the american nuclear society",
        "year": 2007
    },
    "JCK7O4sD": {
        "id": "JCK7O4sD",
        "title": "Fast Computation of the Neutron Transport Calculation with a Graphic Processing Unit (GPU)",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Yasuhiro Kodama",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Yoshihiro Yamane",
                "org": ""
            },
            {
                "name": "Yasunori Ohoka",
                "org": ""
            },
            {
                "name": "Masahiro Tatsumi",
                "org": ""
            }
        ],
        "venue": "Transactions of the american nuclear society",
        "year": 2008
    },
    "HrSdOY1H": {
        "id": "HrSdOY1H",
        "title": "A New Framework of Resonance Calculation Method Based on the Sub-group Method (1); Theory",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Hiroki Koike",
                "org": ""
            },
            {
                "name": "Yoshihiro Yamane",
                "org": ""
            }
        ],
        "venue": "Transactions of the american nuclear society",
        "year": 2009
    },
    "lw0kXRyM": {
        "id": "lw0kXRyM",
        "title": "A new optimization algorithm for in-core fuel shuffling sequence of BWR",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Masayuki Toujou",
                "org": ""
            },
            {
                "name": "Kentarou Komori",
                "org": ""
            },
            {
                "name": "Yasunori Kitamura",
                "org": ""
            },
            {
                "name": "Yoshihiro Yamane",
                "org": ""
            }
        ],
        "venue": "Transactions of the american nuclear society",
        "year": 2005
    },
    "x01sn2gd": {
        "id": "x01sn2gd",
        "title": "Comparison of subcriticality monitoring methods for accelerator-driven system",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Koshi Taguchi",
                "org": ""
            },
            {
                "name": "Yoshihiro Yamane",
                "org": ""
            },
            {
                "name": "Yasunori Kitamura",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "Transactions of the american nuclear society",
        "year": 2004
    },
    "gQzRJlVT": {
        "id": "gQzRJlVT",
        "title": "A New Framework of Resonance Calculation Method Based on the Sub-group Method (2); Calculation",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Hiroki Koike",
                "org": ""
            },
            {
                "name": "Yoshihiro Yamane",
                "org": ""
            }
        ],
        "venue": "Transactions of the american nuclear society",
        "year": 2009
    },
    "2zPvb6Wz": {
        "id": "2zPvb6Wz",
        "title": "Development of a Resonance Calculation Method based on Discrete Treatment of Energy Ranges",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Hiroki Koike",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Yoshihiro Yamane",
                "org": ""
            }
        ],
        "venue": "Transactions of the american nuclear society",
        "year": 2008
    },
    "K3rVMqD3": {
        "id": "K3rVMqD3",
        "title": "An Improved Inverse Analysis Model for Core Calculation of Fuel Loading Pattern Optimization in LWRs",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Hoai Nam Tran",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Yoshihiro Yamane",
                "org": ""
            }
        ],
        "venue": "Transactions of the american nuclear society",
        "year": 2009
    },
    "cR858AWN": {
        "id": "cR858AWN",
        "title": "Subcriticality Estimation of Large FBR by Detectable Multiplication Factor kdet",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Kei Sugawara",
                "org": ""
            },
            {
                "name": "Yoshihiro Yamane",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Shigeaki Okajima",
                "org": ""
            }
        ],
        "venue": "Transactions of the american nuclear society",
        "year": 2009
    },
    "UcRPSRZk": {
        "id": "UcRPSRZk",
        "title": "Optimization of Batch Power Sharing to Improve Discharge Burnup for Multicycle",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Tomoki Iwata",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Yoshihiro Yamane",
                "org": ""
            }
        ],
        "venue": "Transactions of the american nuclear society",
        "year": 2008
    },
    "OJrZozVR": {
        "id": "OJrZozVR",
        "title": "Applicability of the SP3 nodal method for BWR pin-by-pin core analysis with staggered mesh",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Kenichi Tada",
                "org": ""
            },
            {
                "name": "Yasunori Kitamura",
                "org": ""
            },
            {
                "name": "Yoshihiro Yamane",
                "org": ""
            }
        ],
        "venue": "Transactions of the american nuclear society",
        "year": 2007
    },
    "qJuTzGNy": {
        "id": "qJuTzGNy",
        "title": "Application of a game console for fast reactor physics computation",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Yasuhiro Kodama",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Yoshihiro Yamane",
                "org": ""
            }
        ],
        "venue": "Transactions of the american nuclear society",
        "year": 2008
    },
    "6q5VuO0I": {
        "id": "6q5VuO0I",
        "title": "Measurements of Reactivity Worth of Rare-Earth Elements at Kyoto University Critical Assembly",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Hidemasa Okochi",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Yoshihiro Yamane",
                "org": ""
            },
            {
                "name": "Takanori Kitada",
                "org": ""
            },
            {
                "name": "Hironobu Unesaki",
                "org": ""
            }
        ],
        "venue": "Transactions of the american nuclear society",
        "year": 2009
    },
    "HHxaC1nO": {
        "id": "HHxaC1nO",
        "title": "Cost evaluation of power uprate due to reduction of in-core power peaking factor",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Masafumi Adachi",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Yoshihiro Yamane",
                "org": ""
            },
            {
                "name": "Yasunori Kitamura",
                "org": ""
            }
        ],
        "venue": "Transactions of the american nuclear society",
        "year": 2005
    },
    "l0wLLHL3": {
        "id": "l0wLLHL3",
        "title": "Treatment of staggered mesh in BWR pin-by-pin fine mesh core analysis",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Kenichi Tada",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Masato Watanabe",
                "org": ""
            },
            {
                "name": "Hiroshi Noda",
                "org": ""
            },
            {
                "name": "Yasunori Kitamura",
                "org": ""
            },
            {
                "name": "Yoshihiro Yamane",
                "org": ""
            }
        ],
        "venue": "Transactions of the american nuclear society",
        "year": 2007
    },
    "LfsLdaRC": {
        "id": "LfsLdaRC",
        "title": "Simultaneous in-core optimization of PWR tandem cycles",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Erina Sugimura",
                "org": ""
            },
            {
                "name": "Yasunori Kitamura",
                "org": ""
            },
            {
                "name": "Yoshihiro Yamane",
                "org": ""
            }
        ],
        "venue": "Transactions of the american nuclear society",
        "year": 2004
    },
    "ExLWhdNL": {
        "id": "ExLWhdNL",
        "title": "Development of Er-SHB fuel : Critical experiments and analyses of homogeneously erbia-loaded cores in KUCA",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Yoichi Goto",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Hironobu Unesaki",
                "org": ""
            },
            {
                "name": "Toshikazu Takeda",
                "org": ""
            },
            {
                "name": "Masaaki Mori",
                "org": ""
            },
            {
                "name": "Masatoshi Yamasaki",
                "org": ""
            }
        ],
        "venue": "Transactions of the american nuclear society",
        "year": 2007
    },
    "ARGerCMQ": {
        "id": "ARGerCMQ",
        "title": "The Resonance Treatment in the AEGIS code",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Naoki Sugimura",
                "org": ""
            },
            {
                "name": "Masato Tabuchi",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Masahiro Tatsumi",
                "org": ""
            }
        ],
        "venue": "Transactions of the american nuclear society",
        "year": 2009
    },
    "cG4lMIvQ": {
        "id": "cG4lMIvQ",
        "title": "Calculation models of AEGIS, an advanced neutronics solver of next generation",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Naoki Sugimura",
                "org": ""
            },
            {
                "name": "Tadashi Ushio",
                "org": ""
            }
        ],
        "venue": "Transactions of the american nuclear society",
        "year": 2005
    },
    "HHETQDkn": {
        "id": "HHETQDkn",
        "title": "The Experiment and Analysis on Erbia Credit Super-High-Burnup Fuel",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Masatoshi Yamasaki",
                "org": ""
            },
            {
                "name": "Hironobu Unesaki",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "Transactions of the american nuclear society",
        "year": 2009
    },
    "fr8Qxmri": {
        "id": "fr8Qxmri",
        "title": "Effect of anisotropic scattering in PWR/APWR radial-reflector calculations",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Naoki Sugimura",
                "org": ""
            },
            {
                "name": "Tadashi Ushio",
                "org": ""
            }
        ],
        "venue": "Transactions of the american nuclear society",
        "year": 2005
    },
    "lbh4LcV9": {
        "id": "lbh4LcV9",
        "title": "Comparison of 2-group/9-group nodal-transport calculations in 3-D pin-by-pin geometry",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Masahiro Tatsumi",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "Transactions of the american nuclear society",
        "year": 2004
    },
    "yOOgweoY": {
        "id": "yOOgweoY",
        "title": "Investigation of Theoretical Approach to Establish Energy Group Structure for BWR Pin-by-Pin Core Analysis",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Tatsuya Fujita",
                "org": ""
            },
            {
                "name": "Kazumasa Otsuka",
                "org": ""
            },
            {
                "name": "Kenichi Tada",
                "org": ""
            },
            {
                "name": "Tomohiro Endo",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Shinya Kosaka",
                "org": ""
            },
            {
                "name": "Go Hirano",
                "org": ""
            }
        ],
        "venue": "Transactions of the american nuclear society",
        "year": 2010
    },
    "22yZIdh7": {
        "id": "22yZIdh7",
        "title": "The Study on Erbia Credit Super-High-Burnup Fuel with Isotopically Modified Erbia",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Masatoshi Yamasaki",
                "org": ""
            },
            {
                "name": "Hironobu Unesaki",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "Transactions of the american nuclear society",
        "year": 2010
    },
    "jyvr5QRY": {
        "id": "jyvr5QRY",
        "title": "Application of Discontinuity Factor for Integro-differential Transport Equation",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "Transactions of the american nuclear society",
        "year": 2009
    },
    "Mgk2pA7D": {
        "id": "Mgk2pA7D",
        "title": "AEGIS/SCOPE2, a next-generation In-core fuel management system (1) lattice physics code, AEGIS",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Naoki Sugimura",
                "org": ""
            },
            {
                "name": "Tadashi Ushio",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Masahiro Tatsumi",
                "org": ""
            }
        ],
        "venue": "Transactions of the american nuclear society",
        "year": 2007
    },
    "b0tiMGoy": {
        "id": "b0tiMGoy",
        "title": "RECENT PROGRESS AND APPLICATIONS OF RESONANCE CALCULATION METHOD",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "Transactions of the american nuclear society",
        "year": 2009
    },
    "yMeY4Hs4": {
        "id": "yMeY4Hs4",
        "title": "Improvement of the flat source approximation in the method of characteristics",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "Transactions of the american nuclear society",
        "year": 2006
    },
    "qJZCY0RI": {
        "id": "qJZCY0RI",
        "title": "Accuracy of a rapid cell-heterogeneous calculation method for LWR core analysis",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "Transactions of the american nuclear society",
        "year": 2007
    },
    "ko6IAfm2": {
        "id": "ko6IAfm2",
        "title": "Incorporation of Two-Term Rational Approximation in Tone Method for Resonance Calculation",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Tomohiro Endo",
                "org": ""
            },
            {
                "name": "Go Chiba",
                "org": ""
            }
        ],
        "venue": "Transactions of the american nuclear society",
        "year": 2010
    },
    "OYRVxZyW": {
        "id": "OYRVxZyW",
        "title": "Yet another optimum polar angle quadrature set for the method of characteristics",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Masato Tabuchi",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Tomohiro Endo",
                "org": ""
            },
            {
                "name": "Naoki Sugimura",
                "org": ""
            },
            {
                "name": "Tadashi Ushio",
                "org": ""
            },
            {
                "name": "Masaaki Mori",
                "org": ""
            }
        ],
        "venue": "Transactions of the american nuclear society",
        "year": 2005
    },
    "Ho0AmBHN": {
        "id": "Ho0AmBHN",
        "title": "Application of the krylov subspace method to burnup calculation for lattice physics code",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Masahiro Tatsumi",
                "org": ""
            },
            {
                "name": "Naoki Sugimura",
                "org": ""
            }
        ],
        "venue": "Transactions of the american nuclear society",
        "year": 2006
    },
    "lIJuwX6y": {
        "id": "lIJuwX6y",
        "title": "Approximate treatments of anisotropic scattering in LWR analyses",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "Transactions of the american nuclear society",
        "year": 2007
    },
    "EFMtl2hh": {
        "id": "EFMtl2hh",
        "title": "Verification calculations of AEGIS, an advanced neutronics solver of next generation",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Naoki Sugimura",
                "org": ""
            },
            {
                "name": "Tadashi Ushio",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "Transactions of the american nuclear society",
        "year": 2005
    },
    "UoOhJwEN": {
        "id": "UoOhJwEN",
        "title": "Effect of Uncertainty of Planned Cycle Length in Multicycle Fuel Optimization",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Kazuma Ohori",
                "org": ""
            },
            {
                "name": "Tomohiro Endo",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "Transactions of the american nuclear society",
        "year": 2010
    },
    "0mziRsE5": {
        "id": "0mziRsE5",
        "title": "AEGIS/SCOPE2, a next-generation in-core fuel management system (2) core calculation code, SCOPE2",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Masahiro Tatsumi",
                "org": ""
            },
            {
                "name": "Hideaki Hyoudou",
                "org": ""
            },
            {
                "name": "Naoki Sugimura",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "Transactions of the american nuclear society",
        "year": 2007
    },
    "9mYCHqFo": {
        "id": "9mYCHqFo",
        "title": "Reduction of MOC discretization errors through a minimization of source ratio variances",
        "abstract": "ABSTRACTA new technique to reduce discretization errors for ray tracing in the method of characteristics (MOC) is proposed focusing on depletion calculations of single and multi-assembly geometries. In order to efficiently carry out depletion calculations, a calculation scheme using the superhomogenization (SPH) method can be used. However, the discretization errors are caused by changes of neutron sources and total cross sections according to a depletion. This fact means that improvement of accuracy cannot be expected by the calculation scheme with the SPH method when changes of the above parameters are significant. In order to mitigate this problem, a new approach is developed. In the new approach, the discretization errors are reduced by minimizing a variance of a certain parameter which is composed of a ratio of neutron source to total cross section. The verification results suggest that accuracy is degraded by the SPH method as expected especially in a geometry where neutron sources and total cross s...",
        "keywords": "",
        "authors": [
            {
                "name": "Masato Tabuchi",
                "org": "Department of Material Physics and Energy Engineering, Graduate School of Engineering, Nagoya University, Furo-cho, Chikusa-ku, Japan; Nuclear Engineering Ltd., Nishi-ku, Japan"
            },
            {
                "name": "Akio Yamamoto",
                "org": "Department of Material Physics and Energy Engineering, Graduate School of Engineering, Nagoya University, Furo-cho, Chikusa-ku, Japan"
            },
            {
                "name": "Tomohiro Endo",
                "org": "Department of Material Physics and Energy Engineering, Graduate School of Engineering, Nagoya University, Furo-cho, Chikusa-ku, Japan"
            },
            {
                "name": "Masahiro Tatsumi",
                "org": "Nuclear Engineering Ltd., Nishi-ku, Japan"
            }
        ],
        "venue": "Journal of Nuclear Science and Technology",
        "year": 2016
    },
    "5jLVIBQT": {
        "id": "5jLVIBQT",
        "title": "Discontinuity Factors for Simplified P3 Theory",
        "abstract": "AbstractNew discontinuity factors (DFs), i.e., individual and common DFs, for the simplified P3 (SP3) theory are proposed. In the individual DFs, two DFs are used for zeroth- and second-order angular moments in order to preserve first- and third-order angular moments of SP3 at a surface of the homogenized region. Contrarily, the same value of DF is used for zeroth- and second-order angular moments, and the first-order angular moment is preserved in the common DF. Theoretical derivation for these DFs are described, and then, actual numerical calculation procedures for these DFs are explained. Verification results in color-set geometries loaded with UO2 and mixed oxide fuel assemblies indicate the validity of the present method for cell-homogenized pin-by-pin SP3 calculations. Homogenization errors on keff and pin-power distribution are significantly reduced by the present DFs. The proposed DFs can be used for practical pin-by-pin core analyses using the SP3 theory.",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": "Nagoya University, Graduate School of Engineering, Furo-cho, Chikusa-ku, Nagoya, Japan 464-8603"
            },
            {
                "name": "Tatsuya Sakamoto",
                "org": "Nagoya University, Graduate School of Engineering, Furo-cho, Chikusa-ku, Nagoya, Japan 464-8603"
            },
            {
                "name": "Tomohiro Endo",
                "org": "Nagoya University, Graduate School of Engineering, Furo-cho, Chikusa-ku, Nagoya, Japan 464-8603"
            }
        ],
        "venue": "Nuclear Science and Engineering",
        "year": 2016
    },
    "WF0jsZWi": {
        "id": "WF0jsZWi",
        "title": "Bias factor method using random sampling technique",
        "abstract": "ABSTRACTToward the practical use of the bias factor method for actual light water reactor core analyses, the bias factor method using the random sampling technique is newly proposed. The bias factor method is one of the correction methods using information of E/C values in existing measurable systems, to reduce biases and uncertainties of predicted core characteristics parameters. By the aid of the random sampling technique, our proposed bias factor method can be carried out using only forward calculations without any adjoint calculations, and can easily take into account burnup and thermal-hydraulic feedback effects, which are difficult points in the practical application to actual core analyses. Although the statistical error due to the random sampling technique is inevitable in the proposed method, the statistical error can be simply quantified by the resampling technique such as the bootstrap method. As one of the feasibility studies, effectiveness of the proposed method is verified through a numerica...",
        "keywords": "",
        "authors": [
            {
                "name": "Tomohiro Endo",
                "org": "Graduate School of Engineering, Nagoya University, Furo-cho, Chikusa-ku, Aichi 464-8603, Japan"
            },
            {
                "name": "Akio Yamamoto",
                "org": "Graduate School of Engineering, Nagoya University, Furo-cho, Chikusa-ku, Aichi 464-8603, Japan"
            },
            {
                "name": "Tomoaki Watanabe",
                "org": "Graduate School of Engineering, Nagoya University, Furo-cho, Chikusa-ku, Aichi 464-8603, Japan"
            }
        ],
        "venue": "Journal of Nuclear Science and Technology",
        "year": 2016
    },
    "n3sATHsG": {
        "id": "n3sATHsG",
        "title": "An efficient execution of Monte Carlo simulation based on delta-tracking method using GPUs",
        "abstract": "ABSTRACTAn efficient execution method for Monte Carlo simulation using graphic processing unit (GPU) is proposed. The delta-tracking method is used since the delta-tracking method can reduce conditional branches and complexity of code implementation, which degrade computational performance on GPUs. In order to improve parallel efficiency in the eigenvalue calculation, generated fission neutrons are recorded using the atomic operation which avoids the data race in GPUs. We also propose a method to efficiently tally neutron flux in a region. The present method is based on the atomic operation and use of fixed-point type number instead of common floating-point type number. The verification calculations using the C5G7 benchmark problem show effectiveness of the proposed numerical algorithms on GPUs through comparison with calculations using central processing units.",
        "keywords": "",
        "authors": [
            {
                "name": "Takuya Okubo",
                "org": "Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Japan"
            },
            {
                "name": "Tomohiro Endo",
                "org": "Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Japan"
            },
            {
                "name": "Akio Yamamoto",
                "org": "Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Japan"
            }
        ],
        "venue": "Journal of Nuclear Science and Technology",
        "year": 2017
    },
    "8pau7jWg": {
        "id": "8pau7jWg",
        "title": "A CMFD Acceleration Method for SP3 Advanced Nodal Method",
        "abstract": "AbstractFlux-level-fixup (FF) coarse-mesh finite difference (CMFD) (FF-CMFD), which increases numerical stability during nonlinear iterations for the SP3 advanced nodal method, is proposed as an improved CMFD implementation. In contrast to the scalar flux that appeared in the advanced nodal method with diffusion theory, the second flux moment \u03d52 in the SP3 method could take a very small value since it can take both positive and negative values in a node. This is a root cause of inefficiency of the SP3 advanced nodal method when conventional CMFD acceleration is directly applied. In the proposed FF-CMFD method, a constant value is added to the second flux moment \u03d52 to fix up its value to a sufficiently large positive value for stable numerical calculations. The efficiency of the FF-CMFD method is verified through benchmark calculations.",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": "Nagoya University, Engineering Building No. 5, Furo-cho, Chikusa-ku, Nagoya, Japan, 464-8603"
            },
            {
                "name": "Tatsuya Sakamoto",
                "org": "Nagoya University, Engineering Building No. 5, Furo-cho, Chikusa-ku, Nagoya, Japan, 464-8603"
            },
            {
                "name": "Tomohiro Endo",
                "org": "Nagoya University, Engineering Building No. 5, Furo-cho, Chikusa-ku, Nagoya, Japan, 464-8603"
            }
        ],
        "venue": "Nuclear Science and Engineering",
        "year": 2016
    },
    "F5qhfdkG": {
        "id": "F5qhfdkG",
        "title": "Estimation of modeling approximation errors using data assimilation with the minimum variance approach",
        "abstract": "ABSTRACTIn this paper, we estimate prediction errors owing to approximations in calculation models (modeling approximation error) using the data assimilation method. Correlations between the modeling approximation error and neutronics parameters obtained through calculations are evaluated in test configurations and then the evaluated correlations are used to predict the modeling approximation errors in design configuration. Formulae to estimate the modeling approximation error using the correlations are derived based on the minimum variance approach and the physical interpretation of the formulae is discussed through simple cases. The proposed method is applied in 2 \u00d7 2 and 3 \u00d7 3 fuel assembly geometries using specifications of the KAIST benchmark problem. The correlation between the modeling approximation error and parameters (neutron leakage in each fuel assembly) is estimated in 2 \u00d7 2 fuel assemblies and then the modeling approximation error in 3 \u00d7 3 fuel assemblies is predicted using the correlation. ...",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": "Graduate School of Engineering, Department of Material, Physics, and Energy Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Japan"
            },
            {
                "name": "Kuniharu Kinoshita",
                "org": "Graduate School of Engineering, Department of Material, Physics, and Energy Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Japan"
            },
            {
                "name": "Tomohiro Endo",
                "org": "Graduate School of Engineering, Department of Material, Physics, and Energy Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Japan"
            }
        ],
        "venue": "Journal of Nuclear Science and Technology",
        "year": 2017
    },
    "5ma58HLJ": {
        "id": "5ma58HLJ",
        "title": "Estimation of sensitivity coefficients of core characteristics based on reduced-order modeling using sensitivity matrix of assembly characteristics",
        "abstract": "ABSTRACTWe propose an estimation method of sensitivity coefficients of core neutronics parameters based on a multi-level reduced-order modeling approach. The idea is to use lower-level models to identify the dominant input parameter variations, constrained to the so-called active subspace, which are employed to determine the sensitivity coefficients of the core neutronic parameters. In our implementation, the lower-level model is represented by two-dimensional assembly calculations, which are employed in the preparation of the few-group cross-sections for core-wide calculations. The active subspace basis is estimated using the singular value decomposition of sensitivity matrices of assembly neutronics parameters. In numerical verification calculation, sensitivity coefficients of core characteristics for a typical three-loop PWR equilibrium-cycle are estimated using the proposed method and the direct method. Comparison of these two results shows that the proposed method well reproduces the results obtained...",
        "keywords": "",
        "authors": [
            {
                "name": "Ryota Katano",
                "org": "Department of Material Physics and Energy Engineering, Graduate School of Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Japan"
            },
            {
                "name": "Tomohiro Endo",
                "org": "Department of Material Physics and Energy Engineering, Graduate School of Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Japan"
            },
            {
                "name": "Akio Yamamoto",
                "org": "Department of Material Physics and Energy Engineering, Graduate School of Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Japan"
            },
            {
                "name": "Mohammad Abdo",
                "org": "Department of Nuclear Engineering, North Carolina State University, Raleigh, NC, USA"
            },
            {
                "name": "Hany S. Abdel-Khalik",
                "org": ""
            }
        ],
        "venue": "Journal of Nuclear Science and Technology",
        "year": 2017
    },
    "60r7DLfr": {
        "id": "60r7DLfr",
        "title": "Automated generation of burnup chain for reactor analysis applications",
        "abstract": "Abstract This paper presents the development of an automated generation of burnup chain for reactor analysis applications. Algorithms are proposed to reevaluate decay modes, branching ratios and effective fission product (FP) cumulative yields of a given list of important FPs taking into account intermediate reactions. A new burnup chain is generated using the updated data sources taken from the JENDL FP decay data file 2011 and Fission yields data file 2011. The new burnup chain is output according to the format for the SRAC code system. Verification has been performed to evaluate the accuracy of the new burnup chain. The results show that the new burnup chain reproduces well the results of a reference one with 193 fission products used in SRAC. Burnup calculations using the new burnup chain have also been performed based on UO2 and MOX fuel pin cells and compared with a reference chain th2cm6fp193bp6T.",
        "keywords": "",
        "authors": [
            {
                "name": "V.-P. Tran",
                "org": ""
            },
            {
                "name": "Hoai Nam Tran",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Tomohiro Endo",
                "org": ""
            }
        ],
        "venue": "Kerntechnik",
        "year": 2017
    },
    "XsIe5sHm": {
        "id": "XsIe5sHm",
        "title": "GENESIS: A Three-Dimensional Heterogeneous Transport Solver Based on the Legendre Polynomial Expansion of Angular Flux Method",
        "abstract": "AbstractA heterogeneous transport solver in three-dimensional (3-D) geometry, GENESIS, is developed incorporating recent developments in the method of characteristics (MOC) in 3-D geometry. The Legendre Polynomial Expansion of Angular Flux (LEAF) method is implemented in the GENESIS code, in which neutron transport is calculated in two-dimensional (2-D) characteristics planes rather than in one-dimensional characteristics lines adopted in the conventional approach of 3-D MOC. Unlike the planar MOC method that combines 2-D MOC calculations through axial leakages, the GENESIS code explicitly considers angular and spatial dependence of outgoing and incoming angular fluxes between axial planes. Thus, the GENESIS code eliminates a crucial approximation used in the planar MOC method: No approximation is used for axial leakage treatment. The GENESIS code can handle flexible shapes of objects in rectangular or hexagonal geometry. A two-level, multigroup generalized coarse mesh rebalance acceleration method is ado...",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": "Nagoya University, Graduate School of Engineering, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan"
            },
            {
                "name": "Akinori Giho",
                "org": "Nagoya University, Graduate School of Engineering, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan"
            },
            {
                "name": "Yuki Kato",
                "org": "DENSO Corporation, Kariya, Aichi Prefecture, Japan"
            },
            {
                "name": "Tomohiro Endo",
                "org": "Nagoya University, Graduate School of Engineering, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan"
            }
        ],
        "venue": "Nuclear Science and Engineering",
        "year": 2017
    },
    "hwyi3bD2": {
        "id": "hwyi3bD2",
        "title": "Recent developments in the GENESIS code based on the Legendre polynomial expansion of angular flux method",
        "abstract": "Abstract   This paper describes recent development activities of the GENESIS code, which is a transport code for heterogeneous three-dimensional geometry, focusing on applications to reactor core analysis. For the treatment of anisotropic scattering, the concept of the simplified Pn method is introduced in order to reduce storage of flux moments. The accuracy of the present method is verified through a benchmark problem. Next, the iteration stability of the GENESIS code for the highly voided condition, which would appear in a severe accident (e.g., design extension) conditions, is discussed. The efficiencies of the coarse mesh finite difference and generalized coarse mesh rebalance acceleration methods are verified with various stabilization techniques. Use of the effective diffusion coefficient and the artificial grid diffusion coefficients are found to be effective to stabilize the acceleration calculation in highly voided conditions.",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": "Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan"
            },
            {
                "name": "Akinori Giho",
                "org": "Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan"
            },
            {
                "name": "Tomohiro Endo",
                "org": "Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan"
            }
        ],
        "venue": "Nuclear Engineering and Technology",
        "year": 2017
    },
    "HNnBCKH8": {
        "id": "HNnBCKH8",
        "title": "Estimation of sensitivity coefficient based on lasso-type penalized linear regression",
        "abstract": "ABSTRACTWe proposed the penalized regression \u2018adaptive smooth-lasso\u2019 for the estimation of sensitivity coefficients of the neutronics parameters. The proposed method utilizes the variation of the microscopic cross-sections and the neutronics parameters obtained by random sampling. The weighted penalty term of the proposed method is more appropriate for the estimation of the sensitivity of neutronics parameters to the microscopic cross-section than that of the conventional methods. In a numerical verification calculation, sensitivity coefficients of keff of an accelerator-driven system are estimated using the proposed method, the conventional penalized regression, and the direct method. Comparison of these results indicates that the proposed method is superior to the conventional penalized linear regression from the viewpoint of reproduction of the reference sensitivity coefficients obtained by the direct method. Through the verification calculations, the proposed method can be a candidate for a practical ...",
        "keywords": "",
        "authors": [
            {
                "name": "Ryota Katano",
                "org": " Nuclear Science and Engineering Center, Japan Atomic Energy Agency, Tokai-mura, Japan"
            },
            {
                "name": "Tomohiro Endo",
                "org": " Department of Applied Energy, Graduate School of Engineering, Nagoya University, Nagoya, Japan"
            },
            {
                "name": "Akio Yamamoto",
                "org": " Department of Applied Energy, Graduate School of Engineering, Nagoya University, Nagoya, Japan"
            },
            {
                "name": "Kazufumi Tsujimoto",
                "org": " Nuclear Science and Engineering Center, Japan Atomic Energy Agency, Tokai-mura, Japan"
            }
        ],
        "venue": "Journal of Nuclear Science and Technology",
        "year": 2018
    },
    "ZcLviTrH": {
        "id": "ZcLviTrH",
        "title": "Flux Region Assignment Method Using Ray Trace Information for the Method of Characteristics to Improve Cache Efficiency",
        "abstract": "AbstractA flux region assignment algorithm to increase cache efficiency for the method of characteristics (MOC) is proposed. In order to minimize the stride of memory access, flux region identifications are assigned based on the ray trace sequence during the MOC calculation. The present method is implemented in the three-dimensional transport code GENESIS and its performance is confirmed through verification calculations ranging from single pressurized water reactor (PWR) fuel assembly to PWR full-core benchmark problems. Quantitative comparison of cache efficiency is carried out and the present method shows improved cache efficiency, which results in a reduction in computation time. The present method can reduce computational time by improving cache efficiency while suppressing memory requirement.",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": "Nagoya University, Graduate School of Engineering, Furo-cho, Chikusa-ku, Nagoya, Japan, 464-8603"
            },
            {
                "name": "Akinori Giho",
                "org": "Nagoya University, Graduate School of Engineering, Furo-cho, Chikusa-ku, Nagoya, Japan, 464-8603"
            },
            {
                "name": "Tomohiro Endo",
                "org": "Nagoya University, Graduate School of Engineering, Furo-cho, Chikusa-ku, Nagoya, Japan, 464-8603"
            }
        ],
        "venue": "Nuclear Science and Engineering",
        "year": 2018
    },
    "CGL5lQAi": {
        "id": "CGL5lQAi",
        "title": "Underestimation of statistical uncertainty of local tallies in Monte Carlo eigenvalue calculation for simple and LWR lattice geometries",
        "abstract": "ABSTRACTA prediction method of the true variance of local tally in a Monte Carlo (MC) critical calculation is developed. In the MC calculation, the effective multiplication factor (keff) and the fission rate distribution are estimated by simulating fission chain reactions. The statistical uncertainty of calculation result is commonly estimated by the standard error based on the central limit theorem. However, the evaluated statistical uncertainty would be underestimated when the inter-cycle correlation is not appropriately taken into account. In this study, a theoretical formula of the underestimation ratio (UR) of the statistical uncertainty for a local tally is derived using the eigenfunction expansion and the Autoregressive model. Note that the UR is defined by the ratio of uncertainty estimated by a MC calculation to the true statistical uncertainty. The proposed method is applied to one-dimensional slab and multi-assembly geometries with reflective boundary conditions. In the one-dimensional slab geo...",
        "keywords": "",
        "authors": [
            {
                "name": "Koji Hayashi",
                "org": "Graduate School of Engineering, Nagoya University, Nagoya, Japan"
            },
            {
                "name": "Tomohiro Endo",
                "org": "Graduate School of Engineering, Nagoya University, Nagoya, Japan"
            },
            {
                "name": "Akio Yamamoto",
                "org": "Graduate School of Engineering, Nagoya University, Nagoya, Japan"
            }
        ],
        "venue": "Journal of Nuclear Science and Technology",
        "year": 2018
    },
    "K1QKFnaI": {
        "id": "K1QKFnaI",
        "title": "Statistical error estimation of the Feynman-\u03b1 method using the bootstrap method",
        "abstract": "ABSTRACTApplicability of the bootstrap method is investigated to estimate the statistical error of the Feynman-\u03b1 method, which is one of the subcritical measurement techniques on the basis of reactor noise analysis. In the Feynman-\u03b1 method, the statistical error can be simply estimated from multiple measurements of reactor noise, however it requires additional measurement time to repeat the multiple times of measurements. Using a resampling technique called \u201cbootstrap method,\u201d standard deviation and confidence interval of measurement results obtained by the Feynman-\u03b1 method can be estimated as the statistical error, using only a single measurement of reactor noise. In order to validate our proposed technique, we carried out a passive measurement of reactor noise without any external source, i.e. with only inherent neutron source by spontaneous fission and (\u03b1,n) reactions in nuclear fuels at the Kyoto University Criticality Assembly. Through the actual measurement, it is confirmed that the bootstrap method...",
        "keywords": "",
        "authors": [
            {
                "name": "Tomohiro Endo",
                "org": "Graduate School of Engineering, Nagoya University, Furo-cho, Chikusa-ku, Aichi, 464-8603, Japan"
            },
            {
                "name": "Akio Yamamoto",
                "org": "Graduate School of Engineering, Nagoya University, Furo-cho, Chikusa-ku, Aichi, 464-8603, Japan"
            },
            {
                "name": "Takahiro Yagi",
                "org": "Nuclear Safety Technology Center, Hakusan, Bunkyo-ku, Tokyo, 112-8604, Japan"
            },
            {
                "name": "Cheol Ho Pyeon",
                "org": "Research Reactor Institute, Kyoto University, Asashiro-nishi, Kumatori-cho, Sennan-gun, Osaka, 590-0494, Japan"
            }
        ],
        "venue": "Journal of Nuclear Science and Technology",
        "year": 2016
    },
    "Ow5SWmQ6": {
        "id": "Ow5SWmQ6",
        "title": "Comparison of theoretical formulae and bootstrap method for statistical error estimation of Feynman-\u03b1 method",
        "abstract": "Abstract   This paper discusses the statistical error of the variance-to-mean ratio, or the  Y  value in the Feynman-    \u03b1     method, from a single measurement of reactor noise. As a theoretical approach, two practical theoretical formulae are derived to estimate the statistical error of  Y : one is based on the propagation of uncertainty with unbiased estimators for the third- and fourth-order central moments; the other is a simplified formula that reuses the  Y  value under the fundamental mode approximation, where the subcriticality is approximately less than 10,000\u202fpcm. As a numerical approach, the bootstrap method is improved to efficiently estimate the correlations of  Y  between different counting gate widths, or covariance matrix      \u03a3  Y     , due to the bunching method. Through an actual reactor noise experiment at the Kyoto University Criticality Assembly, the statistical errors of  Y  using the theoretical formulae and the bootstrap method are validated by comparing the reference statistical errors that are estimated from the multiple experiments of reactor noise. Furthermore, the impact of      \u03a3  Y      on the statistical error of the prompt neutron decay constant     \u03b1     is numerically investigated. Consequently, in the case of this experimental analysis, it was confirmed that the bootstrap method with the correlations of  Y  seems to be slightly better from the viewpoint of the coverage probability of the estimated confidence intervals of     \u03b1    , although the fitting error method without the correlation of  Y  could be useful for the order estimation of the statistical error of     \u03b1    .",
        "keywords": "",
        "authors": [
            {
                "name": "Tomohiro Endo",
                "org": "Graduate School of Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan"
            },
            {
                "name": "Akio Yamamoto",
                "org": "Graduate School of Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan"
            }
        ],
        "venue": "Annals of Nuclear Energy",
        "year": 2019
    },
    "IQJAiHtE": {
        "id": "IQJAiHtE",
        "title": "Utilization of Regionwise Even-Parity Discontinuity Factor to Reduce Discretization Error of MOC",
        "abstract": "AbstractTo reduce angular and spatial discretization error of the method of characteristics with a coarse calculation condition, the regionwise even-parity discontinuity factor (EPDF) for transport calculations is evaluated through an iterative procedure using only the regionwise scalar flux, i.e., without the odd-parity angular flux, the partial current, or the net current at the region boundary. The regionwise EPDF is evaluated in a single-assembly geometry with the reflective boundary condition. The evaluated EPDF is applied to a 2\u00a0\u00d7\u00a02 colorset assembly and core configurations, and the performance is compared to that of the conventional superhomogenization (SPH) method. The calculation results indicate that (1) no convergence issue is observed during the iteration process to estimate the EPDF, (2) the performance of the regionwise EPDF is better than that of the conventional SPH method, and (3) the normalization of the EPDF is necessary to incorporate different surface scalar flux levels among differen...",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": "Nagoya University, Graduate School of Engineering, Furo-cho, Chikusa-ku, Nagoya, Japan, 464-8603"
            },
            {
                "name": "Akinori Giho",
                "org": "Nagoya University, Graduate School of Engineering, Furo-cho, Chikusa-ku, Nagoya, Japan, 464-8603"
            },
            {
                "name": "Tomohiro Endo",
                "org": "Nagoya University, Graduate School of Engineering, Furo-cho, Chikusa-ku, Nagoya, Japan, 464-8603"
            }
        ],
        "venue": "Nuclear Science and Engineering",
        "year": 2019
    },
    "FjjmCeAT": {
        "id": "FjjmCeAT",
        "title": "Experimental validation of unique combination numbers for third- and fourth-order neutron correlation factors of zero-power reactor noise",
        "abstract": "ABSTRACTZero-power reactor noise is useful for subcriticality measurements. Based on the nuclear reactor physics and the theory of neutron detection, this paper theoretically clarifies that the third- and fourth-order neutron correlation factors Y3 and Y4 can be expressed as functions of the second-order neutron correlation factor Y. In particular, if the neutron-counting gate width is sufficiently large, the saturation values Y3/Y2 and Y4/Y3 are almost equal to the unique combination numbers, \u20183\u2019 and \u201815,\u2019 for a source-driven subcritical system, where the subcriticality is less than 10,000\u00a0pcm. These unique combination numbers, \u20183\u2019 and \u201815,\u2019 for Y3/Y2 and Y4/Y3 were validated using actual zero-power reactor noise measurements carried out at the Kyoto University Criticality Assembly. In this study, the estimation of statistical errors and correlations between different gate widths owing to the bunching method was achieved by the moving block bootstrap method. For a sufficiently long measured reactor noise...",
        "keywords": "",
        "authors": [
            {
                "name": "Tomohiro Endo",
                "org": "Graduate School of Engineering, Nagoya University, Chikusa-ku, Nagoya, Japan"
            },
            {
                "name": "Akio Yamamoto",
                "org": "Graduate School of Engineering, Nagoya University, Chikusa-ku, Nagoya, Japan"
            },
            {
                "name": "Masao Yamanaka",
                "org": "Division of Nuclear Engineering Science, Institute for Integrated Radiation and Nuclear Science, Kyoto University, Osaka, Japan"
            },
            {
                "name": "Cheol Ho Pyeon",
                "org": "Division of Nuclear Engineering Science, Institute for Integrated Radiation and Nuclear Science, Kyoto University, Osaka, Japan"
            }
        ],
        "venue": "Journal of Nuclear Science and Technology",
        "year": 2019
    },
    "CBtoxNIM": {
        "id": "CBtoxNIM",
        "title": "A New Interpretation of Discontinuity Factor",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": "Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Japan 464-8603"
            },
            {
                "name": "Tomohiro Endo",
                "org": "Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Japan 464-8603"
            }
        ],
        "venue": "Nuclear Science and Engineering",
        "year": 2019
    },
    "13i1wxNS": {
        "id": "13i1wxNS",
        "title": "A simple treatment of increased gap due to fuel assembly bowing through correction of cross sections",
        "abstract": "ABSTRACTIncreased fuel assembly gap due to bowing in commercial light-water reactors (LWRs) has an impact on local pin-power distribution due to increased local moderation. In order to consider the effect of increased assembly gap without explicit consideration of increased gap width, a correction method of cross sections in the gap region is proposed. In this cross section correction method, the average chord length of gap region is preserved to capture the effect of increased gap width. The validity of the present method is confirmed by verification calculations in a single assembly and 5\u00a0\u00d7\u00a05 assembly geometries using the GENESIS code, which is a transport code based on the method of characteristics.",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": "Graduate School of Engineering, Nagoya Univeristy, Nagoya, Japan"
            },
            {
                "name": "Tomohiro Endo",
                "org": "Graduate School of Engineering, Nagoya Univeristy, Nagoya, Japan"
            },
            {
                "name": "Hiroaki Nagano",
                "org": "Fuel Engineering Department, Nuclear Fuel Industries, Ltd., Osaka, Japan"
            },
            {
                "name": "Yasunori Ohoka",
                "org": "Fuel Engineering Department, Nuclear Fuel Industries, Ltd., Osaka, Japan"
            },
            {
                "name": "Kento Yamamoto",
                "org": "Fuel Engineering Department, Nuclear Fuel Industries, Ltd., Osaka, Japan"
            }
        ],
        "venue": "Journal of Nuclear Science and Technology",
        "year": 2019
    },
    "wduLALW4": {
        "id": "wduLALW4",
        "title": "Transport consistent diffusion coefficient for CMFD acceleration and comparison of convergence properties",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": "Graduate School of Engineering, Nagoya Univeristy, Nagoya, Japan"
            },
            {
                "name": "Tomohiro Endo",
                "org": "Graduate School of Engineering, Nagoya Univeristy, Nagoya, Japan"
            },
            {
                "name": "Akinori Giho",
                "org": "Independent Scholar"
            }
        ],
        "venue": "Journal of Nuclear Science and Technology",
        "year": 2019
    },
    "cjgGynaY": {
        "id": "cjgGynaY",
        "title": "Uncertainty Quantification of LWR Core Characteristics Using Random Sampling Method",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "akio yamamoto",
                "org": ""
            },
            {
                "name": "kuniharu kinoshita",
                "org": ""
            },
            {
                "name": "tomoaki watanabe",
                "org": ""
            },
            {
                "name": "tomohiro endo",
                "org": ""
            },
            {
                "name": "yasuhiro kodama",
                "org": ""
            },
            {
                "name": "yasunori ohoka",
                "org": ""
            },
            {
                "name": "tadashi ushio",
                "org": ""
            },
            {
                "name": "hiroaki nagano",
                "org": ""
            }
        ],
        "venue": "Nuclear Science and Engineering",
        "year": 2015
    },
    "DFnMnyMf": {
        "id": "DFnMnyMf",
        "title": "Radially and azimuthally dependent resonance self-shielding treatment for general multi-region geometry based on a unified theory",
        "abstract": "ABSTRACTA unified resonance self-shielding method, which can treat general sub-divided fuel regions, is developed for lattice physics calculations in reactor physics field. In a past study, a hybrid resonance treatment has been developed by theoretically integrating equivalence theory and ultra-fine-group slowing-down calculation. It can be applied to a wide range of neutron spectrum conditions including low moderator density ranges in severe accident states, as long as each fuel region is not sub-divided. In order to extend the method for radially and azimuthally sub-divided multi-region geometry, a new resonance treatment is established by incorporating the essence of sub-group method. The present method is composed of two-step flux calculation, i.e. \u2018coarse geometry + fine energy\u2019 (first step) and \u2018fine geometry + coarse energy\u2019 (second step) calculations. The first step corresponds to a hybrid model of the equivalence theory and the ultra-fine-group calculation, and the second step corresponds to the ...",
        "keywords": "",
        "authors": [
            {
                "name": "Hiroki Koike",
                "org": "Reactor Core & Safety Engineering Department, Nuclear Energy System Division, Mitsubishi Heavy Industries, Ltd., Hyogo-ku, Kobe, Japan"
            },
            {
                "name": "Kazuki Kirimura",
                "org": "Reactor Core & Safety Engineering Department, Nuclear Energy System Division, Mitsubishi Heavy Industries, Ltd., Hyogo-ku, Kobe, Japan"
            },
            {
                "name": "Kazuya Yamaji",
                "org": "Reactor Core & Safety Engineering Department, Nuclear Energy System Division, Mitsubishi Heavy Industries, Ltd., Hyogo-ku, Kobe, Japan"
            },
            {
                "name": "Shinya Kosaka",
                "org": "Reactor Core & Safety Engineering Department, Nuclear Energy System Division, Mitsubishi Heavy Industries, Ltd., Hyogo-ku, Kobe, Japan"
            },
            {
                "name": "Akio Yamamoto",
                "org": "Department of Materials, Physics and Energy Engineering, Nagoya University, Chikusaku, Nagoya, Japan"
            }
        ],
        "venue": "Journal of Nuclear Science and Technology",
        "year": 2018
    },
    "eaHYFott": {
        "id": "eaHYFott",
        "title": "Cross-section adjustment methods based on minimum variance unbiased estimation",
        "abstract": "ABSTRACTOn the basis of the minimum variance approach, the unified formulation for three types of the cross-section adjustment methods has been derived in a straightforward way without assuming the normal distribution. These methods are intended to minimize the variances of the predicted target core parameters, the adjusted cross-section set, and the calculated integral experimental values. The first and the second methods are found to be slightly different from the extended and the conventional cross-section adjustment methods based on the Bayesian approach with the normal distribution assumption, respectively. However, they become equivalent in some cases and results. The third method is a new method, which is necessary from the viewpoint of the symmetry of the formulation. In addition, it is verified by numerical calculations that the derived formulation gives the minimized variances as intended. The derivation procedure proposed in the present paper is potentially applicable to developing more sophist...",
        "keywords": "",
        "authors": [
            {
                "name": "Kenji Yokoyama",
                "org": "Japan Atomic Energy Agency, Ibaraki, Japan"
            },
            {
                "name": "Akio Yamamoto",
                "org": "Graduate School of Engineering, Nagoya University, Aichi, Japan"
            }
        ],
        "venue": "Journal of Nuclear Science and Technology",
        "year": 2016
    },
    "VsiJmLyr": {
        "id": "VsiJmLyr",
        "title": "Dimension-reduced cross-section adjustment method based on minimum variance unbiased estimation",
        "abstract": "ABSTRACTA new formulation of the cross-section adjustment methodology with the dimensionality-reduction technique has been derived in the light of the fact that it is often used under the condition of ill-posed problem, where the number of integral experimental quantities is less than the number of adjusted nuclear data parameters. This new formulation is proposed as the dimension-reduced conventional cross-section adjustment method (DRCA). The derivation of DRCA is based on the minimum variance unbiased estimation (MVUE), and the assumption of normal distribution is not used. The result of DRCA depends on a user-defined matrix that determines the dimension-reduced feature subspace. We examined three variations of DRCA, namely, DRCA1, DRCA2, and DRCA3, which employ (1) the nuclear data covariance matrix as the user-defined matrix, (2) the sensitivity coefficient matrix postmultiplied by the nuclear data covariance matrix, and (3) the sensitivity coefficient matrix, respectively. Mathematical investigation...",
        "keywords": "",
        "authors": [
            {
                "name": "Kenji Yokoyama",
                "org": "Nuclear Science and Engineering Center, Japan Atomic Energy Agency, Ibaraki, Japan"
            },
            {
                "name": "Akio Yamamoto",
                "org": "Department of Applied Energy, Graduate School of Engineering, Nagoya University, Nagoya, Japan"
            },
            {
                "name": "Takanori Kitada",
                "org": "Division of Sustainable Energy and Environmental Engineering, Graduate School of Engineering, Osaka University, Osaka, Japan"
            }
        ],
        "venue": "Journal of Nuclear Science and Technology",
        "year": 2018
    },
    "QmTjNRtK": {
        "id": "QmTjNRtK",
        "title": "A coupling model for the two-stage core calculation method with subchannel analysis for boiling water reactors",
        "abstract": "Abstract   The two-stage core analysis method is widely used for BWR core analysis. The purpose of this study is to develop a core analysis model coupled with subchannel analysis within the two-stage calculation scheme using an assembly-based thermal-hydraulics calculation in the core analysis. The model changes the 2D lattice physics scheme, and couples with 3D subchannel analysis which evaluates the thermal-hydraulics characteristics within the coolant flow area divided as some subchannel regions. In order to couple with these two analyses, some BWR fuel assembly parameters are assumed and verified. The developed model is evaluated for the heterogeneous problem with and without a control rod. The present model is especially effective for the control rod inserted condition. The present model can incorporate the subchannel effect into the current two-stage core calculation method.",
        "keywords": "",
        "authors": [
            {
                "name": "Takeshi Mitsuyasu",
                "org": "Hitachi, Ltd., 7-1-1, Omika, Hitachi-shi, Ibaraki 319-1292, Japan"
            },
            {
                "name": "Takeshi Mitsuyasu",
                "org": "Hitachi, Ltd., 7-1-1, Omika, Hitachi-shi, Ibaraki 319-1292, Japan"
            },
            {
                "name": "Motoo Aoyama",
                "org": "Hitachi, Ltd., 7-1-1, Omika, Hitachi-shi, Ibaraki 319-1292, Japan"
            },
            {
                "name": "Akio Yamamoto",
                "org": "Department of Materials, Physics and Energy Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan"
            }
        ],
        "venue": "Annals of Nuclear Energy",
        "year": 2017
    },
    "Btt676E9": {
        "id": "Btt676E9",
        "title": "Neutron transport models of AEGIS : An advanced next-generation neutronics design system",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Naoki Sugimura",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Tadashi Ushio",
                "org": ""
            },
            {
                "name": "Masaaki Mori",
                "org": ""
            },
            {
                "name": "Masato Tabuchi",
                "org": ""
            },
            {
                "name": "Tomohiro Endo",
                "org": ""
            }
        ],
        "venue": "Nuclear Science and Engineering",
        "year": 2007
    },
    "g8z1jmoD": {
        "id": "g8z1jmoD",
        "title": "AEGIS: AN ADVANCED LATTICE PHYSICS CODE FOR LIGHT WATER REACTOR ANALYSES",
        "abstract": "",
        "keywords": [
            "method of characteristics",
            "verification and validation"
        ],
        "authors": [
            {
                "name": "akio yamamoto",
                "org": ""
            },
            {
                "name": "tomohiro endo",
                "org": ""
            },
            {
                "name": "masato tabuchi",
                "org": ""
            },
            {
                "name": "naoki sugimura",
                "org": ""
            },
            {
                "name": "tadashi ushio",
                "org": ""
            },
            {
                "name": "masaaki mori",
                "org": ""
            },
            {
                "name": "masahiro tatsumi",
                "org": ""
            },
            {
                "name": "yasunori ohoka",
                "org": ""
            }
        ],
        "venue": "Nuclear Engineering and Technology",
        "year": 2010
    },
    "It8norCB": {
        "id": "It8norCB",
        "title": "Risk factors for fatal subarachnoid hemorrhage: the Japan Collaborative Cohort Study.",
        "abstract": "The present study aimed to identify risk factors for mortality due to subarachnoid hemorrhage (SAH) using a comprehensive questionnaire from the Japan Collaborative Cohort (JACC) Study, a Japan-wide population-based prospective study.A total of 109,293 individuals (45,551 men and 63,742 women, aged 40 to 79 years) free of stroke at entry participated in the JACC Study between 1988 and 1990. Participants were followed up annually until they died or moved away from the surveyed community, or until the end of 1999. A diagnosis of death from SAH was based on the International Classification of Diseases, 10th revision (ICD-10). The age-adjusted univariate and multivariate hazard ratios (HR) and 95% confidence intervals (CI) of various factors were calculated in sex-stratified and sex-specific analyses using the Cox proportional hazards regression model.A total of 244 individuals (88 men and 156 women) died from SAH during the follow-up of 1 086 963 person-years. Our univariate analyses confirmed that preference for salty foods and history of blood transfusion, as well as hypertension, family history of stroke, cigarette smoking, heavy alcohol consumption, and low BMI, had statistically significant associations with mortality due to SAH. Multivariable analyses revealed that history of blood transfusion was an independent significant risk factor (HR=4.2 [95%CI, 2.1 to 8.5]) for men, while preference for salty foods or heavy drinking were not.History of blood transfusion was found to be an independent risk. The association between SAH and blood transfusion warranted further study.",
        "keywords": [
            "blood transfusion cohort studies risk factors subarachnoid hemorrhage",
            "hazard ratio",
            "prospective study",
            "family history",
            "cohort study",
            "regression model",
            "multivariate analyses",
            "confidence interval",
            "statistical significance",
            "risk factors"
        ],
        "authors": [
            {
                "name": "Yamada Shigeki",
                "org": "Dept of Health and Environmental Sciences, Graduate School of Medicine Kyoto University, Konoe-cho, Yoshida, Sakyo-ku, Kyoto, 606-8501, Japan."
            },
            {
                "name": "Koizumi Akio",
                "org": ""
            },
            {
                "name": "Iso Hiroyasu",
                "org": ""
            },
            {
                "name": "Wada Yasuhiko",
                "org": ""
            },
            {
                "name": "Watanabe Yoshiyuki",
                "org": ""
            },
            {
                "name": "Date Chigusa",
                "org": ""
            },
            {
                "name": "Yamamoto Akio",
                "org": ""
            },
            {
                "name": "Kikuchi Shogo",
                "org": ""
            },
            {
                "name": "Inaba Yutaka",
                "org": ""
            },
            {
                "name": "Toyoshima Hideaki",
                "org": ""
            },
            {
                "name": "Kondo Takaaki",
                "org": ""
            },
            {
                "name": "Tamakoshi Akiko",
                "org": ""
            },
            {
                "name": "null null",
                "org": ""
            }
        ],
        "venue": "Stroke; a journal of cerebral circulation",
        "year": 2003
    },
    "01mDYYgi": {
        "id": "01mDYYgi",
        "title": "Psychological attitudes and risk of breast cancer in Japan: a prospective study.",
        "abstract": "To examine the association between psychological factors and the risk of breast cancer prospectively in a non-Western population.Data from the Japan Collaborative Cohort (JACC) study were analyzed. From 1988 to 1990, 34,497 women aged 40-79 years completed a questionnaire on medical, lifestyle and psychosocial factors. The rate ratios (RRs) of their responses were computed by fitting to proportional hazards models.During the mean follow-up period of 7.5 years, 149 breast cancer cases were documented. Those individuals who possessed \"ikigai\" (Japanese term meaning something that made one's life worth living) showed a significantly lower risk of breast cancer (multivariate-adjusted RR=0.66; 95% confidence interval [CI]=0.47-0.94). Those who perceived themselves as able to make decisions quickly also had a lower risk of breast cancer (multivariate-adjusted RR=0.56; 95% CI=0.36-0.87). The other factors investigated, including ease of anger arousal and self-perceived stress of daily life were not associated with breast cancer risk.Although further studies will be necessary to verify these findings, our results suggest that having \"ikigai\" and being decisive decrease an individual's subsequent risk of breast cancer.",
        "keywords": [
            "Breast cancer",
            "Psychological factors",
            "Ikigai",
            "Decisiveness",
            "Prospective studies"
        ],
        "authors": [
            {
                "name": "Wakai Kenji",
                "org": "Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, 1-1 Kanokoden, Chikusa-ku, Nagoya, 464-8681, Japan. wakai@med.nagoya-u.ac.jp"
            },
            {
                "name": "Kojima Masayo",
                "org": ""
            },
            {
                "name": "Nishio Kazuko",
                "org": ""
            },
            {
                "name": "Suzuki Sadao",
                "org": ""
            },
            {
                "name": "Niwa Yoshimitsu",
                "org": ""
            },
            {
                "name": "Lin Yingsong",
                "org": ""
            },
            {
                "name": "Kondo Takaaki",
                "org": ""
            },
            {
                "name": "Yatsuya Hiroshi",
                "org": ""
            },
            {
                "name": "Tamakoshi Koji",
                "org": ""
            },
            {
                "name": "Yamamoto Akio",
                "org": ""
            },
            {
                "name": "Tokudome Shinkan",
                "org": ""
            },
            {
                "name": "Toyoshima Hideaki",
                "org": ""
            },
            {
                "name": "Tamakoshi Akiko",
                "org": ""
            },
            {
                "name": "null null",
                "org": ""
            }
        ],
        "venue": "Cancer causes & control : CCC",
        "year": 2007
    },
    "10rPU93x": {
        "id": "10rPU93x",
        "title": "and Stroke Walking and Sports Participation and Mortality From Coronary Heart Disease",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Shogo Kikuchi",
                "org": ""
            },
            {
                "name": "Akio Koizumi",
                "org": ""
            },
            {
                "name": "Takaaki Kondo",
                "org": ""
            },
            {
                "name": "Yoshiyuki Watanabe",
                "org": ""
            },
            {
                "name": "Yasuhiko Hiroyuki Noda",
                "org": ""
            },
            {
                "name": "Hiroyasu Iso",
                "org": ""
            },
            {
                "name": "Hideaki Toyoshima",
                "org": ""
            },
            {
                "name": "Chigusa Date",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2010
    },
    "BUbtHZC5": {
        "id": "BUbtHZC5",
        "title": "Fruit, vegetable and bean intake and mortality from cardiovascular disease among Japanese men and women: the JACC Study.",
        "abstract": "To examine the association of plant-based food intakes with CVD and total mortality among Japanese. In the Japan Collaborative Cohort Study for Evaluation of Cancer Risk, 25 206 men and 34 279 women aged 40-79 years, whose fruit, vegetable and bean intakes were assessed by questionnaire at baseline in 1988-90, were followed for 13 years. Deaths from total stroke, stroke subtypes, CHD and total CVD, according to the International Classification for Diseases 10th Revision, were registered. During 756 054 person-years of follow-up, there were 559 deaths from total stroke, 258 from CHD, 1207 from total CVD and 4514 from total mortality for men, and for women, 494, 194, 1036 and 3092, respectively. Fruit intake was inversely associated with mortality from total stroke (the multivariable hazard ratio (HR (95 % CI)) in the highest v. lowest quartiles = 0.67 (0.55, 0.81)), total CVD (HR = 0.75 (0.66, 0.85)) and total mortality (HR = 0.86 (0.80, 0.92)). Vegetable intake was inversely associated with total CVD (HR = 0.88 (0.78, 0.99)). Bean intake was inversely associated with other CVD (HR = 0.79 (0.64, 0.98)), total CVD (HR = 0.84 (0.74, 0.95)) and total mortality (HR = 0.90 (0.84, 0.96)). Further adjustment for other plant-based foods did not alter the association of fruit intake with mortality from total stroke, total CVD and total mortality, but attenuated the associations of vegetables and beans with mortality risk. In conclusion, intakes of plant-based foods, particularly fruit intake, were associated with reduced mortality from CVD and all causes among Japanese men and women.",
        "keywords": [
            "nutrition",
            "questionnaires",
            "evaluation",
            "cardiovascular system",
            "cvd",
            "classification"
        ],
        "authors": [
            {
                "name": "Nagura Junko",
                "org": "Department of Social Medicine &amp; Cultural Sciences, Research Institute for Neurological Diseases &amp; Geriatrics, Kyoto Prefectural University of Medicine, Kyoto, Japan."
            },
            {
                "name": "Iso Hiroyasu",
                "org": ""
            },
            {
                "name": "Watanabe Yoshiyuki",
                "org": ""
            },
            {
                "name": "Maruyama Koutatsu",
                "org": ""
            },
            {
                "name": "Date Chigusa",
                "org": ""
            },
            {
                "name": "Toyoshima Hideaki",
                "org": ""
            },
            {
                "name": "Yamamoto Akio",
                "org": ""
            },
            {
                "name": "Kikuchi Shogo",
                "org": ""
            },
            {
                "name": "Koizumi Akio",
                "org": ""
            },
            {
                "name": "Kondo Takaaki",
                "org": ""
            },
            {
                "name": "Wada Yasuhiko",
                "org": ""
            },
            {
                "name": "Inaba Yutaka",
                "org": ""
            },
            {
                "name": "Tamakoshi Akiko",
                "org": ""
            },
            {
                "name": "null null",
                "org": ""
            }
        ],
        "venue": "The British journal of nutrition",
        "year": 2009
    },
    "PnXR9brz": {
        "id": "PnXR9brz",
        "title": "Alcohol consumption and mortality from stroke and coronary heart disease among Japanese men and women: the Japan collaborative cohort study.",
        "abstract": "Previous studies have demonstrated the association between alcohol consumption and cardiovascular mortality. However, the sex-specific association between alcohol consumption and mortality from stroke and coronary heart disease remains unclear.Between 1988 and 1990, 34,776 men and 48 906 women aged 40 to 79 years completed a self-administered questionnaire including information about alcohol consumption. They were followed-up for a median duration of 14.2 years.Of the 83,682 respondents, 1628 died from stroke and 736 died from coronary heart disease. For men, heavy drinking (>or=46.0 g ethanol/day) was associated with increased mortality from total, hemorrhagic, and ischemic strokes, whereas light-to-moderate drinking was associated with reduced mortality from total cardiovascular disease, compared with not drinking. The respective multivariable hazard ratios (95% CI) were 1.48 (1.22 to 1.80) for total stoke, 1.67 (1.17 to 2.38) for hemorrhagic stroke, 1.35 (1.04 to 1.75) for ischemic stroke, and 0.88 (0.78 to 1.00) for total cardiovascular disease. Women who were heavy drinkers (>or=46.0 g ethanol/day) showed increased mortality from coronary heart disease, and there was reduced mortality from total cardiovascular disease for drinkers of 0.1 to 22.9 g ethanol per day compared with mortality for nondrinkers. The respective multivariable hazard ratios (95% CI) for the 2 categories of drinkers were 4.10 (1.63 to 10.3) and 0.75 (0.62 to 0.91).Heavy alcohol consumption is associated with increased mortality from total stroke, particularly hemorrhagic stroke, and total cardiovascular disease for men, and from coronary heart disease for women, whereas light-to-moderate drinking may be associated with reduced mortality from cardiovascular disease for both sexes.",
        "keywords": [
            "alcohol consumption coronary heart disease mortality stroke",
            "cohort study"
        ],
        "authors": [
            {
                "name": "Ikehara Satoyo",
                "org": "Public Health, Department of Social and Environmental Medicine, Osaka University, Graduate School of Medicine, Osaka, Japan."
            },
            {
                "name": "Iso Hiroyasu",
                "org": ""
            },
            {
                "name": "Toyoshima Hideaki",
                "org": ""
            },
            {
                "name": "Date Chigusa",
                "org": ""
            },
            {
                "name": "Yamamoto Akio",
                "org": ""
            },
            {
                "name": "Kikuchi Shogo",
                "org": ""
            },
            {
                "name": "Kondo Takaaki",
                "org": ""
            },
            {
                "name": "Watanabe Yoshiyuki",
                "org": ""
            },
            {
                "name": "Koizumi Akio",
                "org": ""
            },
            {
                "name": "Wada Yasuhiko",
                "org": ""
            },
            {
                "name": "Inaba Yutaka",
                "org": ""
            },
            {
                "name": "Tamakoshi Akiko",
                "org": ""
            },
            {
                "name": "null null",
                "org": ""
            }
        ],
        "venue": "Stroke; a journal of cerebral circulation",
        "year": 2008
    },
    "aTCDHT5C": {
        "id": "aTCDHT5C",
        "title": "Relationships of age at menarche and menopause, and reproductive year with mortality from cardiovascular disease in Japanese postmenopausal women: the JACC study.",
        "abstract": "Early menopause is associated with increased risk of coronary heart disease in Caucasian women. However, this association has not been examined in Asian women.We conducted a 10-year cohort study of 37,965 Japanese post-menopausal women aged 40-79 years in the Japan Collaborative Cohort (JACC) Study. Causes of death were determined based on the International Classification of Disease.There were 487 mortality of stroke and 178 mortality of coronary heart disease. Late menarche or early menopause, or shorter duration of reproductive period was not associated with risk of mortality from coronary heart disease. However, compared with women with age at menarche < or =13 years, those with age at menarche > or =17 years tended to have increased risk of mortality from stroke: the multivariable hazard ratio was 1.32 (95% confidence interval [CI]: 0.93-1.87, p = 0.10). Compared with women with age at menopause of > or =49 years, those with age at menopause of <49 years tended to have increased risk of coronary heart disease among women aged 40-64 years; the multivariable hazard ratio was 1.85 (95% CI: 0.92-3.73, p = 0.08).The possible association between early menopause and coronary heart disease among middle-aged women was consistent with the result of observational studies for Caucasian women, and can be explained by a protective effect of endogenous estrogen on the development of atherosclerosis.",
        "keywords": [],
        "authors": [
            {
                "name": "Cui Renzhe",
                "org": "Department of Public Health Medicine, Graduate School of Comprehensive Human Science and Institute of Community Medicine, University of Tsukuba."
            },
            {
                "name": "Iso Hiroyasu",
                "org": ""
            },
            {
                "name": "Toyoshima Hideaki",
                "org": ""
            },
            {
                "name": "Date Chigusa",
                "org": ""
            },
            {
                "name": "Yamamoto Akio",
                "org": ""
            },
            {
                "name": "Kikuchi Shogo",
                "org": ""
            },
            {
                "name": "Kondo Takaaki",
                "org": ""
            },
            {
                "name": "Watanabe Yoshiyuki",
                "org": ""
            },
            {
                "name": "Koizumi Akio",
                "org": ""
            },
            {
                "name": "Inaba Yutaka",
                "org": ""
            },
            {
                "name": "Tamakoshi Akiko",
                "org": ""
            },
            {
                "name": "null null",
                "org": ""
            }
        ],
        "venue": "Journal of epidemiology / Japan Epidemiological Association",
        "year": 2006
    },
    "S32tL6OA": {
        "id": "S32tL6OA",
        "title": "Cigarette smoking and the risk of ovarian cancer in the Japanese population: findings from the Japanese Collaborate Cohort study.",
        "abstract": "The many studies into the relation between cigarette smoking and the risk of ovarian cancer have produced inconsistent results. Here we investigated this relation using data from the Japan Collaborative Cohort Study for Evaluation of Cancer Risk, initiated in 1988.A self-administered questionnaire on smoking habits and other risk factors for cancer was completed by 34 639 Japanese women. After 7.6 years of follow up, 39 cases of ovarian cancer were available for analyses. Cox proportional-hazards models were used to compute relative risks (RR) and to adjust for confounders.Relative to those who had never smoked, the RR of ovarian cancer were 1.63 (95% confidence interval [CI] = 0.21-12.50) for former smokers and 2.27 (95% CI = 0.85-6.08) for current smokers. Among current smokers, the RR were 1.48 (95% CI = 0.20-10.92), 5.56 (95% CI = 1.68-19.06), and 1.86 (95% CI = 0.25-14.30) among women who smoked <10, 10-19, and at least 20 pack-years ([number of cigarettes smoked per day/20] x number of years subject has smoked), respectively, relative to those who had never smoked. A test for trend was statistically significant (P = 0.044).These data indicate that cigarette smoking increases the risk of developing ovarian cancer in the Japanese population.",
        "keywords": [
            "proportional hazards model",
            "cohort study",
            "japanese"
        ],
        "authors": [
            {
                "name": "Niwa Yoshimitsu",
                "org": "Department of Preventive Medicine/Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya, Japan. ytt-niwa@xg7.so-net.ne.jp"
            },
            {
                "name": "Wakai Kenji",
                "org": ""
            },
            {
                "name": "Suzuki Sadao",
                "org": ""
            },
            {
                "name": "Tamakoshi Koji",
                "org": ""
            },
            {
                "name": "Lin Yingsong",
                "org": ""
            },
            {
                "name": "Yatsuya Hiroshi",
                "org": ""
            },
            {
                "name": "Kondo Takaaki",
                "org": ""
            },
            {
                "name": "Nishio Kazuko",
                "org": ""
            },
            {
                "name": "Yamamoto Akio",
                "org": ""
            },
            {
                "name": "Tokudome Shinkan",
                "org": ""
            },
            {
                "name": "Hamajima Nobuyuki",
                "org": ""
            },
            {
                "name": "Toyoshima Hideaki",
                "org": ""
            },
            {
                "name": "Tamakoshi Akiko",
                "org": ""
            },
            {
                "name": "null null",
                "org": ""
            }
        ],
        "venue": "The journal of obstetrics and gynaecology research",
        "year": 2005
    },
    "LhyMGD3D": {
        "id": "LhyMGD3D",
        "title": "Relations between dietary sodium and potassium intakes and mortality from cardiovascular disease: the Japan Collaborative Cohort Study for Evaluation of Cancer Risks1-3",
        "abstract": "Background: Limited evidence is available about the relations be- tween sodium and potassium intakes and cardiovascular disease in the general population. Objective: The objective was to investigate relations between so- dium and potassium intakes and cardiovascular disease in Asian populations whose mean sodium intake is generally high. Design:Between1988and1990,atotalof58 730Japanesesubjects (n 23 119 men and 35 611 women) aged 40-79 y with no history of stroke, coronary heart disease, or cancer completed a lifestyle questionnaire including food intake frequency under the Japan Col- laborativeCohortStudyforEvaluationofCancerRisksponsoredby the Ministry of Education, Sports and Science. Results: After 745 161 person-years of follow-up, we documented 986 deaths from stroke (153 subarachnoid hemorrhages, 227 intra- parenchymal hemorrhages, and 510 ischemic strokes) and 424 deaths from coronary heart disease. Sodium intake was positively associatedwithmortalityfromtotalstroke,ischemicstroke,andtotal cardiovascular disease. The multivariable hazard ratio for the high- est versus the lowest quintiles of sodium intake after adjustment for age, sex, and cardiovascular disease risk factors was 1.55 (95% CI: 1.21, 2.00;Pfor trend0.001) for total stroke, 2.04 (95% CI: 1.41, 2.94; P for trend 0.001) for ischemic stroke, and 1.42 (95% CI: 1.20, 1.69; P for trend 0.001) for total cardiovascular disease. Potassium intake was inversely associated with mortality from cor- onary heart disease and total cardiovascular disease. The multivari- able hazard ratio for the highest versus the lowest quintiles of po- tassiumintakewas0.65(95%CI:0.39,1.06;Pfortrend0.083)for coronary heart disease and 0.73 (95% CI: 0.59, 0.92; P for trend 0.018) for total cardiovascular disease, and these associations were more evident for women than for men.",
        "keywords": [
            "88:195-202.",
            "conclusions:ahighsodiumintakeandalowpotassiumintakemay increasetheriskofmortalityfromcardiovasculardisease. amj clin nutr 2008"
        ],
        "authors": [
            {
                "name": "Mitsumasa Umesawa",
                "org": ""
            },
            {
                "name": "Hiroyasu Iso",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Hideaki Toyoshima",
                "org": ""
            },
            {
                "name": "Yoshiyuki Watanabe",
                "org": ""
            },
            {
                "name": "Shogo Kikuchi",
                "org": ""
            },
            {
                "name": "Akio Koizumi",
                "org": ""
            },
            {
                "name": "Takaaki Kondo",
                "org": ""
            },
            {
                "name": "Yutaka Inaba",
                "org": ""
            },
            {
                "name": "Naohito Tanabe",
                "org": ""
            },
            {
                "name": "Akiko Tamakoshi",
                "org": ""
            }
        ],
        "venue": "",
        "year": 0
    },
    "cgMITOJy": {
        "id": "cgMITOJy",
        "title": "Risk and protective factors related to mortality from pneumonia among middleaged and elderly community residents: the JACC Study.",
        "abstract": "There have been few systematic investigations into risk and protective factors for pneumonia related mortality for community residents. This study investigated these factors utilizing a large cohort study on Japanese community residents.Subjects, 110,792 individuals (aged 40-79 years) enrolled in 1988-1990, were followed until death, or when they moved away from the surveyed communities, or the end of 2003. Pneumonia death was defined following 480-486 (International Classification of Diseases, 9th Revision) or J12-J18 (10th Revision). Age-adjusted and multivariate hazard ratios were calculated along with 95% confidence intervals using the Cox proportional hazards model.With 1,112,747 person-years of the study, a total of 1,246 persons died of pneumonia. We found history of blood transfusion (multivariate hazard ratio=2.0 [95% confidence interval: 1.7-2.4]) was a potent novel risk factor. Walking 0.5-1 hour/day (0.8 [0.6-1.0]), 1+ hour/day (0.7 [0.6-0.8]), and/or a history of pregnancy (0.6 [0.4-0.9]) were found to reduce pneumonia mortality. A large body mass index (BMI) (25+kg/m(2)) was a protective factor (0.7 [0.5-0.8]), while low BMI (<18) was confirmed as a risk one (2.1 [1.7-2.6]). Smoking was an important preventable risk factor (1.6 [1.3-1.9], population attributable risk proportion=14%), and its cessation reduced risk (0.7 [0.5-1.0]) to levels comparable to neversmokers (0.7 [0.5-1.0]).The risk and protective factors ascertained here for pneumonia mortality among community residents, history of blood transfusion, large BMI, and walking habits, warrant further study. Smoking cessation may effectively reduce pneumonia mortality.",
        "keywords": [],
        "authors": [
            {
                "name": "Yusuke Inoue",
                "org": ""
            },
            {
                "name": "Akio Koizumi",
                "org": ""
            },
            {
                "name": "Yasuhiko Wada",
                "org": ""
            },
            {
                "name": "Hiroyasu Iso",
                "org": ""
            },
            {
                "name": "Yoshiyuki Watanabe",
                "org": ""
            },
            {
                "name": "Chigusa Date",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Shogo Kikuchi",
                "org": ""
            },
            {
                "name": "Yutaka Inaba",
                "org": ""
            },
            {
                "name": "Hideaki Toyoshima",
                "org": ""
            },
            {
                "name": "Akiko Tamakoshi",
                "org": ""
            }
        ],
        "venue": "Journal of epidemiology / Japan Epidemiological Association",
        "year": 2007
    },
    "gDPHJTpp": {
        "id": "gDPHJTpp",
        "title": "Prospective study of alcohol consumption and breast cancer risk in Japanese women.",
        "abstract": "Epidemiologic evidence is lacking for the association between alcohol consumption and the risk of breast cancer in Japanese women. We addressed this association in a prospective cohort study with an average follow-up of 7.6 years. At baseline (1988-1990), cohort participants completed a self-administered questionnaire that included alcohol use, reproductive history and hormone use. The women were followed up for breast cancer incidence through December 31, 1997. Cox proportional hazards models were used to calculate relative risks (RRs) and 95% confidence intervals (CIs) for breast cancer incidence and any association with alcohol consumption. During a follow-up of 271,412 person-years, we identified 151 women with breast cancer, of whom 45 were current drinkers and 11 drank > or =15 g of alcohol/day. After adjustment for age and other potential risk factors for breast cancer, the RR for current drinkers was 1.27 (95% CI 0.87-1.84) compared to nondrinkers. Average alcohol intake of <15 g/day did not significantly increase the risk for breast cancer. However, risk was significantly increased for women who consumed > or =15 g/day of alcohol (RR = 2.93, 95% CI 1.55-5.54). Age at starting drinking and frequency of consumption per week were not significantly associated with breast cancer risk. Our cohort study demonstrated that Japanese women who consume at least a moderate amount of alcohol have an increased risk of breast cancer.",
        "keywords": [
            "prospective study",
            "breast cancer",
            "cohort study"
        ],
        "authors": [
            {
                "name": "Yingsong Lin",
                "org": ""
            },
            {
                "name": "Shogo Kikuchi",
                "org": ""
            },
            {
                "name": "Koji Tamakoshi",
                "org": ""
            },
            {
                "name": "Kenji Wakai",
                "org": ""
            },
            {
                "name": "Takaaki Kondo",
                "org": ""
            },
            {
                "name": "Yoshimizu Niwa",
                "org": ""
            },
            {
                "name": "Hiroshi Yatsuya",
                "org": ""
            },
            {
                "name": "Kazuko Nishio",
                "org": ""
            },
            {
                "name": "Sadao Suzuki",
                "org": ""
            },
            {
                "name": "Shinkan Tokudome",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Hideaki Toyoshima",
                "org": ""
            },
            {
                "name": "Akiko Tamakoshi",
                "org": ""
            }
        ],
        "venue": "International journal of cancer. Journal international du cancer",
        "year": 2005
    },
    "ixcvUC4U": {
        "id": "ixcvUC4U",
        "title": "Dietary intake of calcium in relation to mortality from cardiovascular disease: the JACC Study.",
        "abstract": "No prospective studies have examined the association between calcium intake and the risk of cardiovascular disease in Japanese populations with a low mean calcium intake.Between 1988 and 1990, 110,792 Japanese subjects (46,465 men and 64,327 women) 40 to 79 years of age without a history of stroke, coronary heart disease, or cancer, completed a lifestyle questionnaire including food intake frequency under the Japan Collaborative Cohort (JACC) Study for Evaluation of Cancer Risk Sponsored by Monbusho. By the end of 1999, after 515,029 person years of follow-up, 566 deaths from stroke (101 subarachnoid hemorrhages, 140 intraparenchymal hemorrhages, and 273 ischemic strokes) and 234 deaths from coronary heart disease had been documented.The intake of total calcium tended to be inversely associated with mortality from total stroke but not from coronary heart disease or total cardiovascular disease for men and women. The inverse association with dairy calcium intake was apparent for total stroke, both hemorrhagic and ischemic. The multivariate relative risk for men with highest versus lowest quintiles of dairy calcium intake was 0.53 (95% CI, 0.34 to 0.81) for total stroke, 0.46 (0.23 to 0.91) for hemorrhagic stroke, and 0.53 (0.29 to 0.99) for ischemic stroke; corresponding relative risks for women were 0.57 (0.38 to 0.86), 0.51 (0.28 to 0.94), and 0.50 (0.27 to 0.95).Dietary calcium intake from dairy products was associated with reduced mortality from stroke for Japanese men and women.",
        "keywords": [
            "calcium follow-up studies mortality stroke"
        ],
        "authors": [
            {
                "name": "Mitsumasa Umesawa",
                "org": ""
            },
            {
                "name": "Hiroyasu Iso",
                "org": ""
            },
            {
                "name": "Chigusa Date",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Hideaki Toyoshima",
                "org": ""
            },
            {
                "name": "Yoshiyuki Watanabe",
                "org": ""
            },
            {
                "name": "Shogo Kikuchi",
                "org": ""
            },
            {
                "name": "Akio Koizumi",
                "org": ""
            },
            {
                "name": "Takaaki Kondo",
                "org": ""
            },
            {
                "name": "Yutaka Inaba",
                "org": ""
            },
            {
                "name": "Naohito Tanabe",
                "org": ""
            },
            {
                "name": "Akiko Tamakoshi",
                "org": ""
            }
        ],
        "venue": "Stroke; a journal of cerebral circulation",
        "year": 2006
    },
    "d3gZgZ93": {
        "id": "d3gZgZ93",
        "title": "Reproducibility and validity of a self-administered food frequency questionnaire used in the JACC study.",
        "abstract": "A self-administered questionnaire on dietary habits used in the JACC Study contained a 40-item food frequency questionnaire (FFQ). Although more than 110 thousand subjects enrolled in JACC Study and responded to the FFQ, no validation study has been conducted to date.Eighty-five volunteers among the cohort members completed 2 FFQs (FFQs 1&2) and 12-day weighed dietary records (WDR). The interval between the two FFQs was one year. During the one year, the subjects carried out a 3-consecutive-day WDR in each season. We tested the reproducibility by using two FFQs. Also, we tested the validity of the FFQ by using the 12-day WDR as a gold standard.The intake frequencies of the 2 FFQs often agreed, showing the Spearman correlation coefficients ranging from 0.42 (edible wild plants) to 0.86 (coffee). The Spearman correlation coefficients of the energy and nutrient intakes from FFQ2, and that of the 12-day WDR were 0.20(energy) to 0.46 (animal protein, potassium). After adjusting the energy intake, the correlation coefficients showed 0.21(fish fat) to 0.51(animal fat). When classifying the FFQ2 and WDR by quartiles and examining the degree of agreement between the two methods, we obtained its median 30%.The FFQ is suitable to deal with a large group of subjects. However, since the energy and the amount of nutrient intake from this FFQ can not show the overall dietary intake situation, the subjects' dietary intake should be assessed by categories.",
        "keywords": [],
        "authors": [
            {
                "name": "Date Chigusa",
                "org": "Department of Nutrition and Food Sciences, Faculty of Human Environmental Sciences, Mukogawa Women's University, Japan. chigusa@cc.nara-wu.ac.jp"
            },
            {
                "name": "Fukui Mitsuru",
                "org": ""
            },
            {
                "name": "Yamamoto Akio",
                "org": ""
            },
            {
                "name": "Wakai Kenji",
                "org": ""
            },
            {
                "name": "Ozeki Azusa",
                "org": ""
            },
            {
                "name": "Motohashi Yutaka",
                "org": ""
            },
            {
                "name": "Adachi Chieko",
                "org": ""
            },
            {
                "name": "Okamoto Naoyuki",
                "org": ""
            },
            {
                "name": "Kurosawa Michiko",
                "org": ""
            },
            {
                "name": "Tokudome Yuko",
                "org": ""
            },
            {
                "name": "Kurisu Yoko",
                "org": ""
            },
            {
                "name": "Watanabe Yoshiyuki",
                "org": ""
            },
            {
                "name": "Ozasa Kotaro",
                "org": ""
            },
            {
                "name": "Nakagawa Shuichi",
                "org": ""
            },
            {
                "name": "Tokui Noritaka",
                "org": ""
            },
            {
                "name": "Yoshimura Takesumi",
                "org": ""
            },
            {
                "name": "Tamakoshi Akiko",
                "org": ""
            },
            {
                "name": "null null",
                "org": ""
            }
        ],
        "venue": "Journal of epidemiology / Japan Epidemiological Association",
        "year": 2005
    },
    "XWUEGM4l": {
        "id": "XWUEGM4l",
        "title": "Smoking Cessation and Mortality from Cardiovascular Disease among Japanese Men and Women",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "hiroyasu iso",
                "org": ""
            },
            {
                "name": "chigusa date",
                "org": ""
            },
            {
                "name": "akio yamamoto",
                "org": ""
            },
            {
                "name": "hideaki toyoshima",
                "org": ""
            },
            {
                "name": "yoshiyuki watanabe",
                "org": ""
            },
            {
                "name": "shogo kikuchi",
                "org": ""
            },
            {
                "name": "akio koizumi",
                "org": ""
            },
            {
                "name": "yasuhiko wada",
                "org": ""
            },
            {
                "name": "takaaki kondo",
                "org": ""
            },
            {
                "name": "yutaka inaba",
                "org": ""
            },
            {
                "name": "hyogo prefectural",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2005
    },
    "CG91sXnG": {
        "id": "CG91sXnG",
        "title": "Dietary intakes of fat and fatty acids and risk of breast cancer: a prospective study in Japan.",
        "abstract": "To examine the possible association of dietary fat and fatty acids with breast cancer risk in a population with a low total fat intake and a high consumption of fish, we analyzed data from the Japan Collaborative Cohort (JACC) Study. From 1988 to 1990, 26 291 women aged 40-79 years completed a questionnaire on dietary and other factors. Intakes of fat or fatty acids were estimated by using a food frequency questionnaire. Rate ratios (RR) were computed by fitting proportional hazards models. During the mean follow-up of 7.6 years, 129 breast cancer cases were documented. We found no clear association of total fat intake with breast cancer risk; the multivariate-adjusted RR across quartiles were 1.00, 1.29, 0.95, and 0.80 (95% confidence interval [CI] 0.46-1.38). A significant decrease in the risk was detected for the highest quartile of intake compared with the lowest for fish fat and long-chain n-3 fatty acids; the RR were 0.56 (95% CI 0.33-0.94) and 0.50 (0.30-0.85), respectively. A decreasing trend in risk was also suggested with an increasing intake of saturated fatty acids (trend P = 0.066). Among postmenopausal women at baseline, the highest quartile of vegetable fat intake was associated with a 2.08-fold increase in risk (95% CI 1.05-4.13). This prospective study did not support any increase in the risk of breast cancer associated with total or saturated fat intake, but it suggested the protective effects of the long-chain n-3 fatty acids that are abundant in fish.",
        "keywords": [
            "breast cancer",
            "fatty acid",
            "prospective study"
        ],
        "authors": [
            {
                "name": "Wakai Kenji",
                "org": "Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, 1-1 Kanokoden, Nagoya 464-8681, Japan. wakai@aichi-cc.jp"
            },
            {
                "name": "Tamakoshi Koji",
                "org": ""
            },
            {
                "name": "Date Chigusa",
                "org": ""
            },
            {
                "name": "Fukui Mitsuru",
                "org": ""
            },
            {
                "name": "Suzuki Sadao",
                "org": ""
            },
            {
                "name": "Lin Yingsong",
                "org": ""
            },
            {
                "name": "Niwa Yoshimitsu",
                "org": ""
            },
            {
                "name": "Nishio Kazuko",
                "org": ""
            },
            {
                "name": "Yatsuya Hiroshi",
                "org": ""
            },
            {
                "name": "Kondo Takaaki",
                "org": ""
            },
            {
                "name": "Tokudome Shinkan",
                "org": ""
            },
            {
                "name": "Yamamoto Akio",
                "org": ""
            },
            {
                "name": "Toyoshima Hideaki",
                "org": ""
            },
            {
                "name": "Tamakoshi Akiko",
                "org": ""
            },
            {
                "name": "null null",
                "org": ""
            }
        ],
        "venue": "Cancer science",
        "year": 2005
    },
    "NIZOGjoS": {
        "id": "NIZOGjoS",
        "title": "Relationship between body mass index and the risk of ovarian cancer in the Japanese population: findings from the Japanese Collaborate Cohort (JACC) study.",
        "abstract": "The incidence of ovarian cancer in Japan has increased since the 1970s. The many studies that have assessed the relationship between body mass index (BMI) and the risk of ovarian cancer have produced contradictory results. Here we investigated this relation using data from the Japan Collaborative Cohort Study for the Evaluation of Cancer Risk, which was initiated in 1988.A self-administered questionnaire on dietary habits and other risk factors for cancer was completed by 36,456 Japanese women. After 7.6 years of follow up, 38 cases of ovarian cancer were available for analysis. Cox proportional-hazards models were used to compute relative risks and to adjust for confounders.Compared to women with BMI of 18.5-24.9 kg/m2, the relative risk of ovarian cancer was 2.24 (95% CI = 1.10-4.21) for BMI of 25.0-29.9 and 1.78 (95% CI = 0.24-13.34) for BMI of > or = 30 kg/m2. A test for trend revealed that this finding was statistically significant (P = 0.014).The results of this study suggest that being overweight is independently associated with a higher risk of developing ovarian cancer in the Japanese population.",
        "keywords": [
            "cohort study",
            "japanese"
        ],
        "authors": [
            {
                "name": "Niwa Yoshimitsu",
                "org": "Department of Preventive Medicine/Biostatistics and Medical Decision Making, Nagoya University Graduate School of Medicine, Nagoya, Japan. niwa@aichi-cc.jp"
            },
            {
                "name": "Yatsuya Hiroshi",
                "org": ""
            },
            {
                "name": "Tamakoshi Koji",
                "org": ""
            },
            {
                "name": "Nishio Kazuko",
                "org": ""
            },
            {
                "name": "Kondo Takaaki",
                "org": ""
            },
            {
                "name": "Lin Yingsong",
                "org": ""
            },
            {
                "name": "Suzuki Sadao",
                "org": ""
            },
            {
                "name": "Wakai Kenji",
                "org": ""
            },
            {
                "name": "Tokudome Shinkan",
                "org": ""
            },
            {
                "name": "Yamamoto Akio",
                "org": ""
            },
            {
                "name": "Hamajima Nobuyuki",
                "org": ""
            },
            {
                "name": "Toyoshima Hideaki",
                "org": ""
            },
            {
                "name": "Tamakoshi Akiko",
                "org": ""
            },
            {
                "name": "null null",
                "org": ""
            }
        ],
        "venue": "The journal of obstetrics and gynaecology research",
        "year": 2005
    },
    "wxyixXUx": {
        "id": "wxyixXUx",
        "title": "Consumption of soy foods and the risk of breast cancer: findings from the Japan Collaborative Cohort (JACC) Study.",
        "abstract": "The association between a lower incidence of breast cancer within the Asian population and the consumption of a diet high in soy has recently been the subject of much attention. To examine whether soy foods really have protective effects against breast cancer and how their influence on breast cancer is modified according to menopausal status, we conducted a population-based, prospective cohort study in Japan.We analyzed the data from the Japan Collaborative Cohort (JACC) Study. From 1988 to 1990, 30,454 women aged 40-79 years, completed a questionnaire on diet and other lifestyle features. Hazard ratios (HRs) were computed to examine the association between soy intake and the risk of breast cancer.During the mean follow-up of 7.6 years, 145 cases of breast cancer were documented. We found no significant association between the risk of breast cancer and consumption of tofu, boiled beans, and miso soup; the multivariate HRs (95% CI) in the highest category of consumption were 1.14 (0.74-1.77), 0.77 (0.47-1.27) and 1.01 (0.65-1.56), respectively. Only among postmenopausal women, we found no significant associations between soy foods and the risk of breast cancer.This prospective study suggests that consumption of soy food has no protective effects against breast cancer. Further large-scale investigations eliciting genetic factors may clarify different roles of various soybean-ingredient foods on the risk of breast cancer.",
        "keywords": [
            "Breast cancer",
            "Breast neoplasms",
            "Soy",
            "Soy foods",
            "Cohort study",
            "Cohort studies"
        ],
        "authors": [
            {
                "name": "Kazuko Nishio",
                "org": "Nagoya University Graduate School of Medicine Department of Preventive Medicine/Biostatistics and Medical Decision Making 65 Tsurumai-cho Showa-ku, Nagoya 466-8550 Japan"
            },
            {
                "name": "Yoshimitsu Niwa",
                "org": "Nagoya University Graduate School of Medicine Department of Preventive Medicine/Biostatistics and Medical Decision Making 65 Tsurumai-cho Showa-ku, Nagoya 466-8550 Japan"
            },
            {
                "name": "Hideaki Toyoshima",
                "org": "Nagoya University Graduate School of Medicine Department of Public Health/Health Information Dynamics, Field of Social Life Science, Program in Health and Community Medicine 65 Tsurumai-cho Showa-ku, Nagoya 466-8550 Japan"
            },
            {
                "name": "Koji Tamakoshi",
                "org": "Nagoya University Graduate School of Medicine Department of Public Health/Health Information Dynamics, Field of Social Life Science, Program in Health and Community Medicine 65 Tsurumai-cho Showa-ku, Nagoya 466-8550 Japan"
            },
            {
                "name": "Takaaki Kondo",
                "org": "Nagoya University Graduate School of Medicine Department of Public Health/Health Information Dynamics, Field of Social Life Science, Program in Health and Community Medicine 65 Tsurumai-cho Showa-ku, Nagoya 466-8550 Japan"
            },
            {
                "name": "Hiroshi Yatsuya",
                "org": "Nagoya University Graduate School of Medicine Department of Public Health/Health Information Dynamics, Field of Social Life Science, Program in Health and Community Medicine 65 Tsurumai-cho Showa-ku, Nagoya 466-8550 Japan"
            },
            {
                "name": "Akio Yamamoto",
                "org": "Hyogo Prefectural Institute of Public Health and Environmental Science Department of Epidemiology 2-1-29 Arata-cho Kobe 652-0032 Japan"
            },
            {
                "name": "Sadao Suzuki",
                "org": "Nagoya City University Graduate School of Medical Sciences Division of Health Promotion and Preventive Medicine 1 Kawasumi, Mizuho-cho Mizuho-ku, Nagoya 467-8601 Japan"
            },
            {
                "name": "Shinkan Tokudome",
                "org": "Nagoya City University Graduate School of Medical Sciences Division of Health Promotion and Preventive Medicine 1 Kawasumi, Mizuho-cho Mizuho-ku, Nagoya 467-8601 Japan"
            },
            {
                "name": "Yingsong Lin",
                "org": "Aichi Medical University Division of Public Health Nagakute 480-1195 Japan"
            },
            {
                "name": "Kenji Wakai",
                "org": "Aichi Cancer Center Research Institute Department of Epidemiology and Prevention 1-1 Kanokoden Chikusa-ku, Nagoya 464-8681 Japan"
            },
            {
                "name": "Nobuyuki Hamajima",
                "org": "Nagoya University Graduate School of Medicine Department of Preventive Medicine/Biostatistics and Medical Decision Making 65 Tsurumai-cho Showa-ku, Nagoya 466-8550 Japan"
            },
            {
                "name": "Akiko Tamakoshi",
                "org": "Nagoya University Graduate School of Medicine Department of Preventive Medicine/Biostatistics and Medical Decision Making 65 Tsurumai-cho Showa-ku, Nagoya 466-8550 Japan"
            }
        ],
        "venue": "Cancer causes & control : CCC",
        "year": 2007
    },
    "mQpucoe4": {
        "id": "mQpucoe4",
        "title": "History of blood transfusion before 1990 is a risk factor for stroke and cardiovascular diseases: the Japan collaborative cohort study (JACC study).",
        "abstract": "We have previously shown novel evidence that history of blood transfusion is a risk factor for mortality from subarachnoid hemorrhage. This study was conducted to assess history of transfusion as a risk factor for other hemorrhagic stroke or ischemic stroke and cardiovascular diseases.A total of 88,312 Japanese participants (36,823 men and 51,489 women), aged 40-79 years, without history of stroke, heart disease or cancer, completed a questionnaire including history of transfusion under the JACC Study from 1988 to 1990. Participants were followed up annually until deceased, or when they moved away from the surveyed community, or at the end of 1999. The underlying causes of death were determined according to the International Classification of Diseases, 10th revision (ICD-10).Total follow-up person-years were 871,437 (males 359,437, females 512,000). During this 10-year period, 309 died from intracerebral hemorrhage, 587 from ischemic stroke and 472 from coronary heart disease. The multivariate relative risks of a transfusion history were 2.16 (95% CI 1.42-3.27, p < 0.001) for intracerebral hemorrhage, 1.63 (95% CI 1.18-2.27, p = 0.004) for ischemic stroke and 1.66 (95% CI 1.17-2.36, p = 0.005) for coronary heart disease, after adjustment for conventional cardiovascular risk factors.A transfusion history was associated with increased mortality from stroke and coronary heart disease.",
        "keywords": [
            "stroke",
            "epidemiology",
            "risk factors",
            "study design",
            "relative risk",
            "cause of death",
            "cohort study"
        ],
        "authors": [
            {
                "name": "Yamada Shigeki",
                "org": "Department of Health and Environmental Sciences, Kyoto University Graduate School of Medicine, Konoe-cho, Yoshida, Sakyo-ku, Kyoto, Japan."
            },
            {
                "name": "Koizumi Akio",
                "org": ""
            },
            {
                "name": "Iso Hiroyasu",
                "org": ""
            },
            {
                "name": "Wada Yasuhiko",
                "org": ""
            },
            {
                "name": "Watanabe Yoshiyuki",
                "org": ""
            },
            {
                "name": "Date Chigusa",
                "org": ""
            },
            {
                "name": "Yamamoto Akio",
                "org": ""
            },
            {
                "name": "Kikuchi Shogo",
                "org": ""
            },
            {
                "name": "Inaba Yutaka",
                "org": ""
            },
            {
                "name": "Kondo Takaaki",
                "org": ""
            },
            {
                "name": "Toyoshima Hideaki",
                "org": ""
            },
            {
                "name": "Tamakoshi Akiko",
                "org": ""
            },
            {
                "name": "null null",
                "org": ""
            }
        ],
        "venue": "Cerebrovascular diseases (Basel, Switzerland)",
        "year": 2005
    },
    "I04bjxbs": {
        "id": "I04bjxbs",
        "title": "Active smoking, passive smoking, and breast cancer risk: findings from the Japan Collaborative Cohort Study for Evaluation of Cancer Risk.",
        "abstract": "Evidence is lacking regarding the relationship between cigarette smoking and breast cancer in Japanese women. We examined the association between breast cancer incidence and active and passive smoking in the Japan Collaborative Cohort Study for Evaluation of Cancer Risk.Our study comprised 34,401 women aged 40-79 years who had not been diagnosed previously with breast cancer and who provided information on smoking status at baseline (1988-1990). The subjects were followed from enrollment until December 31, 2001. Cox proportional-hazards models were used to estimate the hazard ratio (HR) and 95% confidence interval (CI) for the association between breast cancer incidence and tobacco smoke.During 271,412 person-years of follow-up, we identified 208 incident cases of breast cancer. Active smoking did not increase the risk of breast cancer, with a HR for current smokers of 0.67 (95% CI: 0.32-1.38). Furthermore, an increased risk of breast cancer was not observed in current smokers who smoked a greater number of cigarettes each day. Overall, passive smoking at home or in public spaces was also not associated with an increased risk of breast cancer among nonsmokers. Women who reported passive smoking during childhood had a statistically insignificant increase in risk (HR: 1.24; 95% CI: 0.84-1.85), compared with those who had not been exposed during this time.Smoking may not be associated with an increased risk of breast cancer in this cohort of Japanese women.",
        "keywords": [],
        "authors": [
            {
                "name": "Lin Yingsong",
                "org": "Department of Public Health, Aichi Medical University School of Medicine, Aichi, Japan."
            },
            {
                "name": "Kikuchi Shogo",
                "org": ""
            },
            {
                "name": "Tamakoshi Koji",
                "org": ""
            },
            {
                "name": "Wakai Kenji",
                "org": ""
            },
            {
                "name": "Kondo Takaaki",
                "org": ""
            },
            {
                "name": "Niwa Yoshimitsu",
                "org": ""
            },
            {
                "name": "Yatsuya Hiroshi",
                "org": ""
            },
            {
                "name": "Nishio Kazuko",
                "org": ""
            },
            {
                "name": "Suzuki Sadao",
                "org": ""
            },
            {
                "name": "Tokudome Shinkan",
                "org": ""
            },
            {
                "name": "Yamamoto Akio",
                "org": ""
            },
            {
                "name": "Toyoshima Hideaki",
                "org": ""
            },
            {
                "name": "Mori Mitsuru",
                "org": ""
            },
            {
                "name": "Tamakoshi Akiko",
                "org": ""
            },
            {
                "name": "null null",
                "org": ""
            }
        ],
        "venue": "Journal of epidemiology / Japan Epidemiological Association",
        "year": 2008
    },
    "TWxfqGhz": {
        "id": "TWxfqGhz",
        "title": "Perceived mental stress and mortality from cardiovascular disease among Japanese men and women: the Japan Collaborative Cohort Study for Evaluation of Cancer Risk Sponsored by Monbusho (JACC Study).",
        "abstract": "Perceived mental stress has been associated with risk of coronary heart disease (CHD) in white men, but no prospective data are available for other ethnic groups.From 1988 to 1990, a total of 73 424 Japanese (30 180 men and 43 244 women), aged 40 to 79 years, without a history of stroke, CHD, or cancer completed a lifestyle questionnaire including perception of mental stress under the Japan Collaborative Cohort Study for Evaluation of Cancer Risk Sponsored by Monbusho (JACC Study). Systematic surveillance was completed until the end of 1997, with a 580 378 person-year follow-up, and the underlying causes of death were determined according to the International Classification of Diseases, 10th revision. For women, there were 316 with total stroke, 113 with CHD, and 643 with total cardiovascular disease (CVD); for men, there were 341, 168, and 778, respectively. Women who reported high stress had a 2-fold higher age-adjusted risk of mortality from total stroke and CHD and 1.5-fold higher risk of total CVD compared with those who reported low stress. Further adjustment for known cardiovascular risk factors and selected psychological variables did not alter the associations materially. The multivariate relative risk for women who perceived high stress versus low stress was 2.24 (95% CI 1.52 to 3.31, P<0.001) for total stroke, 2.28 (95% CI 1.17 to 4.43, P=0.02) for CHD, and 1.64 (95% CI 1.25 to 2.16, P<0.001) for total CVD. For men, these relations were generally weaker but suggestive of myocardial infarction.Perceived mental stress was associated with increased mortality from stroke for women and with CHD for men and women.",
        "keywords": [
            "stress mortality stroke myocardial infarction follow-up studies",
            "cohort study",
            "myocardial infarct"
        ],
        "authors": [
            {
                "name": "Hiroyasu Iso",
                "org": ""
            },
            {
                "name": "Chigusa Date",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Hideaki Toyoshima",
                "org": ""
            },
            {
                "name": "Naohito Tanabe",
                "org": ""
            },
            {
                "name": "Shogo Kikuchi",
                "org": ""
            },
            {
                "name": "Takaaki Kondo",
                "org": ""
            },
            {
                "name": "Yoshiyuki Watanabe",
                "org": ""
            },
            {
                "name": "Yasuhiko Wada",
                "org": ""
            },
            {
                "name": "Teruo Ishibashi",
                "org": ""
            },
            {
                "name": "Hiroshi Suzuki",
                "org": ""
            },
            {
                "name": "Akio Koizumi",
                "org": ""
            },
            {
                "name": "Yutaka Inaba",
                "org": ""
            },
            {
                "name": "Akiko Tamakoshi",
                "org": ""
            },
            {
                "name": "Yoshiyuki Ohno",
                "org": ""
            }
        ],
        "venue": "Circulation",
        "year": 2002
    },
    "VlkYbVX0": {
        "id": "VlkYbVX0",
        "title": "Walking and sports participation and mortality from coronary heart disease and stroke.",
        "abstract": "We aimed to examine the impact of exercise on mortality from cardiovascular disease (CVD) in Asian populations.Few data have been available in Asian countries, where job-related physical activity is higher than that in Western countries.Between 1988 and 1990, 31,023 men and 42,242 women in Japan, ages 40 to 79 years with no history of stroke, coronary heart disease (CHD), or cancer, completed a self-administered questionnaire. Systematic mortality surveillance was performed through 1999, and 1,946 cardiovascular deaths were identified. We chose the second lowest categories of walking and sports participation as the reference to reduce a potential effect of ill health.Men and women who reported having physical activity in the highest category (i.e., walking > or =1 h/day or doing sports > or =5 h/week) had a 20% to 60% lower age-adjusted risk of mortality from CVD, compared with those in the second lowest physical activity category (i.e., walking 0.5 h/day, or sports participation for 1 to 2 h/week). Adjustment for known risk factors, exclusion of individuals who died within two years of baseline inquiry, or gender-specific analysis did not substantially alter these associations. The multivariate-adjusted hazard ratios (95% confidence interval) for the highest versus the second lowest categories of walking or sports participation were 0.71 (0.54 to 0.94) and 0.80 (0.48 to 1.31), respectively, for ischemic stroke (IS); 0.84 (0.64 to 1.09) and 0.51 (0.32 to 0.82), respectively, for CHD; and 0.84 (0.75 to 0.95) and 0.73 (0.60 to 0.90), respectively, for CVD.Physical activity through walking and sports participation might reduce the risk of mortality from IS and CHD.",
        "keywords": [
            "cvd",
            "subarachnid hemorrhage",
            "hr",
            "is",
            "hazard ratio",
            "confidence interval",
            "chd",
            "iph",
            "cardiovascular disease",
            "sah",
            "coronary heart disease",
            "intraparenchymal hemorrhage",
            "ci",
            "ischemic stroke"
        ],
        "authors": [
            {
                "name": "Noda Hiroyuki",
                "org": "Department of Public Health Medicine, Doctoral Program in Social and Environmental Medicine, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Ibaraki, Japan."
            },
            {
                "name": "Iso Hiroyasu",
                "org": ""
            },
            {
                "name": "Toyoshima Hideaki",
                "org": ""
            },
            {
                "name": "Date Chigusa",
                "org": ""
            },
            {
                "name": "Yamamoto Akio",
                "org": ""
            },
            {
                "name": "Kikuchi Shogo",
                "org": ""
            },
            {
                "name": "Koizumi Akio",
                "org": ""
            },
            {
                "name": "Kondo Takaaki",
                "org": ""
            },
            {
                "name": "Watanabe Yoshiyuki",
                "org": ""
            },
            {
                "name": "Wada Yasuhiko",
                "org": ""
            },
            {
                "name": "Inaba Yutaka",
                "org": ""
            },
            {
                "name": "Tamakoshi Akiko",
                "org": ""
            },
            {
                "name": "null null",
                "org": ""
            }
        ],
        "venue": "Journal of the American College of Cardiology",
        "year": 2005
    },
    "N9lkUrMG": {
        "id": "N9lkUrMG",
        "title": "Body mass index and mortality from cardiovascular disease among Japanese men and women: the JACC study.",
        "abstract": "Although overweight is an important risk factor for cardiovascular disease in Western countries, the impact of overweight has not been well elucidated in Japan, where its prevalence is low.A total of 104,928 Japanese (43,889 men and 61,039 women) aged 40 to 79 years, free of stroke, coronary heart disease, and cancer at entry participated in the Japan Collaborative Cohort Study for Evaluation of Cancer Risk Sponsored by Monbusho (JACC Study) between 1988 and 1990. Systematic surveillance was completed until the end of 1999, with 1,042,835 person years of follow-up, and the underlying causes of death were determined based on the International Classification of Diseases.There were 765 total strokes (191 intraparenchymal hemorrhages), 379 coronary heart diseases, and 1707 total cardiovascular diseases for men; and for women, there were 685 (145), 256, and 1432, respectively. Compared with persons with body mass index (BMI) 23.0 to 24.9, those with BMI > or =27.0 kg/m2 had a higher risk of coronary heart disease; for men and women, the respective multivariate relative risk (95% CI) was 2.05 (1.35 to 3.13) and 1.58 (0.95 to 2.62). Persons with BMI <18.5 kg/m2 had higher risk of total stroke and intraparenchymal hemorrhage, for men and women, the respective multivariate relative risk was 1.29 (1.01 to 1.49) and 1.92 (1.49 to 2.47) for total stroke and 1.96 (1.16 to 3.31) and 2.32 (1.36 to 3.97) for intraparenchymal hemorrhage. These excess risks did not alter materially when deaths within 5 years were excluded or when smoking status was taken into account.For Japanese men and women, high BMI was associated with increased risk of coronary heart disease, whereas low BMI was associated with intraparenchymal hemorrhage.",
        "keywords": [
            "body mass index coronary heart disease follow-up studies mortality stroke",
            "relative risk"
        ],
        "authors": [
            {
                "name": "Cui Renzhe",
                "org": "Department of Public Health Medicine, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tuskuba, Ibaraki 305-8575, Japan."
            },
            {
                "name": "Iso Hiroyasu",
                "org": ""
            },
            {
                "name": "Toyoshima Hideaki",
                "org": ""
            },
            {
                "name": "Date Chigusa",
                "org": ""
            },
            {
                "name": "Yamamoto Akio",
                "org": ""
            },
            {
                "name": "Kikuchi Shogo",
                "org": ""
            },
            {
                "name": "Kondo Takaaki",
                "org": ""
            },
            {
                "name": "Watanabe Yoshiyuki",
                "org": ""
            },
            {
                "name": "Koizumi Akio",
                "org": ""
            },
            {
                "name": "Wada Yasuhiko",
                "org": ""
            },
            {
                "name": "Inaba Yutaka",
                "org": ""
            },
            {
                "name": "Tamakoshi Akiko",
                "org": ""
            },
            {
                "name": "null null",
                "org": ""
            }
        ],
        "venue": "Stroke; a journal of cerebral circulation",
        "year": 2005
    },
    "f24yTCfi": {
        "id": "f24yTCfi",
        "title": "Design and Control of a Fish-like Robot Using an Electrostatic Motor",
        "abstract": "This paper presents a project that aims at constructing a biologically inspired fish-like robot. The robot is designed to be capable of propelling itself through oscillations of a flexible caudal fin, like a real underwater fish. In particular, the caudal fin is driven by a mechanism actuated by a unique actuator called electrostatic film motor. In this paper, the dynamics of the electrostatic film motor are briefly introduced so as to well understand its characteristics and behavior. Based on the theoretical analysis and several design considerations inspired by biological concepts, we realize the fish-like robot actuated by an electrostatic film motor and propose swimming control methods for it. Experiments are carried out to confirm the validity of the original design and control. The current robot achieves fish-like maneuvering and approximate velocity of 0.018 m/s in dielectric liquid.",
        "keywords": [
            "fish-like maneuvering",
            "motion control",
            "mobile robots",
            "fish-like robot",
            "flexible caudal fin",
            "swimming control",
            "electrostatic film motor",
            "electrostatic motors",
            "underwater vehicles",
            "biomimetics",
            "underwater fish",
            "oscillations",
            "synchronous motors",
            "robots",
            "propulsion"
        ],
        "authors": [
            {
                "name": "Zu Guang Zhang",
                "org": ""
            },
            {
                "name": "Masahiko Gondo",
                "org": ""
            },
            {
                "name": "Norio Yamashita",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Toshiro Higuchi",
                "org": ""
            }
        ],
        "venue": "ICRA",
        "year": 2007
    },
    "XZUvKBP7": {
        "id": "XZUvKBP7",
        "title": "Modeling of an electrostatic induction actuator for dielectric sheet conveying",
        "abstract": "This paper analyzes sheet transportation using the principle of electrostatic induction motors. This sheet transportation method has the capability of positioning and feeding dielectric sheets in processes and can be an interesting alternative to the existing mechanical conveyor. Although electrostatic sheet transportation was previously proposed based on a unique actuation model, it had limitations in surface resistivity of transported sheets. To break this limitation this paper utilizes another actuation principle namely electrostatic induction for conveying dielectric sheets. This study paper proposes an analytical model for actuation, in which the optimum driving frequency is analytically predicted, showing good agreement with the measured data.",
        "keywords": [
            "surface resistance",
            "modeling",
            "sheet conveying",
            "electrostatic actuator",
            "induction motor"
        ],
        "authors": [
            {
                "name": "Mehdi Modabberifar",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": "Department of Precision Engineering, The University of Tokyo, 7-3-1 Hongo Bunkyo-ku, Tokyo 113-8656, Japan"
            },
            {
                "name": "Toshiro Higuchi",
                "org": "Department of Precision Engineering, The University of Tokyo, 7-3-1 Hongo Bunkyo-ku, Tokyo 113-8656, Japan"
            }
        ],
        "venue": "Sensors & Actuators: A. Physical",
        "year": 2010
    },
    "rmS08Nl4": {
        "id": "rmS08Nl4",
        "title": "Basic Analysis of Stickiness Sensation for Tactile Displays",
        "abstract": "This paper analyzes fingertip behavior on sticky surfaces for synthesizing stickiness sensation. Changes of fingertip contact area were monitored during contacts to sticky surfaces, which were then analyzed with respect to contact force. The analysis revealed that stickiness surfaces cause large hysteresis on the relationship between contact force and area. Based on the analysis, the sticky sensation was simply synthesized by using vacuum pressure. The synthesized sensation elicited a similar feeling as sticky sensation caused by adhesive glue, although the sensation was weaker than the intended one.",
        "keywords": [
            "stickiness sensation",
            "large hysteresis",
            "fingertip behavior",
            "sticky sensation",
            "stickiness surface",
            "adhesive glue",
            "synthesizing stickiness sensation",
            "synthesized sensation",
            "sticky surface",
            "contact force",
            "fingertip contact area",
            "tactile displays",
            "basic analysis",
            "surface texture",
            "contact area"
        ],
        "authors": [
            {
                "name": "Masaaki Yamaoka",
                "org": "Department of Precision Engineering, University of Tokyo, Tokyo, Japan 113-8656"
            },
            {
                "name": "Akio Yamamoto",
                "org": "Department of Precision Engineering, University of Tokyo, Tokyo, Japan 113-8656"
            },
            {
                "name": "Toshiro Higuchi",
                "org": "Department of Precision Engineering, University of Tokyo, Tokyo, Japan 113-8656"
            }
        ],
        "venue": "EuroHaptics",
        "year": 2008
    },
    "8W3Bou0G": {
        "id": "8W3Bou0G",
        "title": "Prototyping of flexible capacitive encoder with un-tethered slider using electrostatic induction",
        "abstract": "Summary This paper describes a capacitive encoder that is characterized by its wireless sensor slider. The main components are made as flexible printed circuit films which thickness is only 0.2 mm. Hence, the sensor can be set up in thin interspaces or on curved surfaces. The sensor consists of a long receiver film and a short transmitter film, respectively containing four-phase and two-phase electrode. The transmitter is used as a slider and the receiver is used as a stator. To realize an un-tethered slider, the sensor employs a unique approach; electric power is supplied to the transmitting electrodes by electrostatic induction, thus removing electric wires from the slider. This un-tethered slider can facilitate the sensitive applications where mechanical disturbance caused by an electric wire can be a problem. The principle was verified by a prototype sensor, which showed a linearity error of +/- 4 micro meters. Motivation",
        "keywords": [
            "printed circuits",
            "electrostatics",
            "films",
            "electrodes",
            "electrostatic induction",
            "linearity",
            "capacitance",
            "electric power",
            "capacitive sensors"
        ],
        "authors": [
            {
                "name": "Fumitaka KIMURA",
                "org": ""
            },
            {
                "name": "Masahiko GONDO",
                "org": ""
            },
            {
                "name": "Norio YAMASHITA",
                "org": ""
            },
            {
                "name": "Akio YAMAMOTO",
                "org": ""
            },
            {
                "name": "Toshiro HIGUCHI",
                "org": ""
            }
        ],
        "venue": "Sensors",
        "year": 2008
    },
    "JvhCxExZ": {
        "id": "JvhCxExZ",
        "title": "Electrostatic tactile display with thin film slider and its application to tactile tele-presentation systems",
        "abstract": "A new electrostatic tactile display is proposed to realize compact tactile display devices that can be incorporated with virtual reality systems. The tactile display of this study consists of a thin conductive film slider with stator electrodes that excite electrostatic forces. Users of the device experience tactile texture sensations by moving the slider with their fingers. The display operates by applying two-phase cyclic voltage patterns to the electrodes. This paper reports on the application of the new tactile display in a tactile tele-presentation system. In the system, a PVDF tactile sensor and DSP controller automatically generate voltage patterns to present surface texture sensations through the tactile display. A sensor, in synchronization with finger motion on the tactile display, scans a texture sample and outputs information about the sample surface. The information is processed by a DSP and fed back to the tactile display in real time. The tactile tele-presentation system was evaluated in texture discrimination tests and demonstrated a 79% correct answer ratio. A transparent electrostatic tactile display is also reported in which the tactile display is combined with an LCD to realize a visual-tactile integrated display system.",
        "keywords": [
            "visual-tactile integrated display system",
            "new electrostatic tactile display",
            "thin film slider",
            "new tactile display",
            "tactile display",
            "transparent electrostatic tactile display",
            "surface texture sensation",
            "device experience tactile texture",
            "compact tactile display device",
            "tactile tele-presentation system",
            "pvdf tactile sensor",
            "real time",
            "thin film",
            "surface texture",
            "electrostatic force",
            "user interface",
            "tactile sensor",
            "virtual reality"
        ],
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": "University of Tokyo, Bunkyo, Tokyo, Japan"
            },
            {
                "name": "Shuichi Nagasawa",
                "org": "University of Tokyo, Bunkyo, Tokyo, Japan"
            },
            {
                "name": "Hiroaki Yamamoto",
                "org": "University of Tokyo, Bunkyo, Tokyo, Japan"
            },
            {
                "name": "Toshiro Higuchitokyo",
                "org": "University of Tokyo, Bunkyo, Tokyo, Japan"
            }
        ],
        "venue": "VRST",
        "year": 2004
    },
    "OBOBhXBN": {
        "id": "OBOBhXBN",
        "title": "Motion Generation in MR Environment Using Electrostatic Film Motor for Motion-Triggered Cine-MRI",
        "abstract": "",
        "keywords": [
            "visualization",
            "biomechanics",
            "capacitive sensors",
            "electrostatic motors",
            "mathematical model",
            "force sensor",
            "data visualisation",
            "electrostatic motor",
            "strain gauge"
        ],
        "authors": [
            {
                "name": "Mayoran Rajendra",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Toshiaki Oda",
                "org": ""
            },
            {
                "name": "Hiroyuki Kataoka",
                "org": ""
            },
            {
                "name": "Hideo Yokota",
                "org": ""
            },
            {
                "name": "Ryutaro Himeno",
                "org": ""
            },
            {
                "name": "Toshiro Higuchi",
                "org": ""
            }
        ],
        "venue": "IEEE-ASME Transactions on Mechatronics",
        "year": 2008
    },
    "D18K43hH": {
        "id": "D18K43hH",
        "title": "A high-power electrostatic motor using skewed electrodes",
        "abstract": "",
        "keywords": [
            "electrostatic motor",
            "linear motor"
        ],
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Toshiki Niino",
                "org": ""
            },
            {
                "name": "Takahisa Ban",
                "org": ""
            },
            {
                "name": "Toshiro Higuchi",
                "org": ""
            }
        ],
        "venue": "Electrical Engineering in Japan",
        "year": 1999
    },
    "X9WDGodY": {
        "id": "X9WDGodY",
        "title": "Effect of Force Feedback on Rubber Hand Illusion",
        "abstract": "Our previous study has proposed a novel approach with a robotic/haptic technology to tactile rubber hand illusion (TRHI) paradigm in order to open new discussions about the manipulation of human body-parts ownership. The results demonstrated that the use of master-slave system can cause the TRHI, enabling a unique condition-active self-touch. As an advanced approach, this study examines the effect of force feedback on the TRHI under the active self-touch. We hypothesize that appropriate force feedback plays an important role to determine our body-parts ownership, people would not experience the TRHI if the force feedback from a fake hand largely differs from the contact force on a real hand. This paper, in particular, discusses how the force feedback affects the TRHI under the active self-touch by variously changing force rendering on the master device.",
        "keywords": [
            "fake hand",
            "force rendering",
            "real hand",
            "rubber hand illusion",
            "force feedback",
            "appropriate force feedback",
            "contact force",
            "unique condition-active self-touch",
            "active self-touch",
            "advanced approach",
            "haptics",
            "human factors",
            "human computer interaction"
        ],
        "authors": [
            {
                "name": "Masayuki Hara",
                "org": ""
            },
            {
                "name": "Hiroyuki Nabae",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Toshiro Higuchi",
                "org": ""
            }
        ],
        "venue": "SMC",
        "year": 2013
    },
    "jWMMm7iM": {
        "id": "jWMMm7iM",
        "title": "Development of a robotic fish using electrostatic film motors: the Seidengyo II robot",
        "abstract": "",
        "keywords": [
            "power transmission",
            "high frequency",
            "high voltage",
            "flexible printed circuit",
            "real time control",
            "oscillations"
        ],
        "authors": [
            {
                "name": "Zu Guang Zhang",
                "org": ""
            },
            {
                "name": "Norio Yamashita",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Toshiro Higuchi",
                "org": ""
            }
        ],
        "venue": "Advanced Robotics",
        "year": 2007
    },
    "hVIV2pt8": {
        "id": "hVIV2pt8",
        "title": "Evaluation of an Electrostatic Film Motor Driven by Two-Four-Phase AC Voltage and Electrostatic Induction",
        "abstract": "",
        "keywords": [
            "induction motors",
            "electrodes",
            "voltage",
            "electric power",
            "electrostatic motors",
            "pneumatic actuators",
            "mechatronics",
            "ac motors",
            "electrostatic induction",
            "cables",
            "network analysis",
            "electromagnetic induction"
        ],
        "authors": [
            {
                "name": "Norio Yamashita",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Masahiko Gondo",
                "org": ""
            },
            {
                "name": "Toshiro Higuchi",
                "org": ""
            }
        ],
        "venue": "ICRA",
        "year": 2007
    },
    "GZcWLzS4": {
        "id": "GZcWLzS4",
        "title": "DC-Operated Electrostatic Impact Drive Actuator",
        "abstract": "",
        "keywords": [
            "linear motor",
            "oscillations",
            "high voltage",
            "electrical circuit"
        ],
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Hiroaki Katsurai",
                "org": ""
            },
            {
                "name": "Toshiro Higuchi",
                "org": ""
            }
        ],
        "venue": "Advanced Robotics",
        "year": 2010
    },
    "dwEjBbch": {
        "id": "dwEjBbch",
        "title": "Producing Softness Sensation on an Electrostatic Texture Display for Rendering Diverse Tactile Feelings",
        "abstract": "This paper investigates the possibility of producing two different tactile feelings on one device. A simple mechanism for softness presentation was integrated with an electrostatic tactile display that can generate surface texture sensations. The principle of softness presentation is contact-width control, where contact width between a fingertip and the display is controlled corresponding to contact force. In the prototype, the softness-producing mechanism deforms the slider film of the electrostatic display so as to control the contact width between the fingertip and the film. Experimental results showed that the prototype could successfully elicit softness sensations, although the perceived softness was slightly harder than the intended softness.",
        "keywords": [
            "elicit softness sensation",
            "electrostatic tactile display",
            "slider film",
            "rendering diverse tactile feelings",
            "softness presentation",
            "contact width",
            "different tactile feeling",
            "electrostatic display",
            "electrostatic texture display",
            "intended softness",
            "producing softness sensation",
            "simple mechanism",
            "contact-width control",
            "prototypes",
            "surface texture",
            "electrostatics",
            "electrodes",
            "display devices",
            "displays",
            "force feedback"
        ],
        "authors": [
            {
                "name": "Hideaki Yokota",
                "org": "University of Tokyo, Japan"
            },
            {
                "name": "Akio Yamamoto",
                "org": "University of Tokyo, Japan"
            },
            {
                "name": "Hiroaki Yamamoto",
                "org": "University of Tokyo, Japan"
            },
            {
                "name": "Toshiro Higuchi",
                "org": "University of Tokyo, Japan"
            }
        ],
        "venue": "WHC",
        "year": 2007
    },
    "8IC6TlSR": {
        "id": "8IC6TlSR",
        "title": "Development of a controller for a high-power electrostatic motor",
        "abstract": "",
        "keywords": [
            "transformer",
            "electrostatic motor",
            "controller",
            "resonance"
        ],
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Toshiki Niino",
                "org": ""
            },
            {
                "name": "Toshiro Higuchi",
                "org": ""
            }
        ],
        "venue": "Electrical Engineering in Japan",
        "year": 2000
    },
    "V9N7U26g": {
        "id": "V9N7U26g",
        "title": "Capacitive-Type Flexible Linear Encoder With Untethered Slider Using Electrostatic Induction",
        "abstract": "",
        "keywords": [
            "encoding",
            "power electronics",
            "capacitance",
            "electrostatic induction",
            "flexible electronics",
            "transmitters",
            "wireless communication",
            "capacitive sensors",
            "electrodes",
            "electric power",
            "linear encoder",
            "electromagnetic induction",
            "incremental encoder"
        ],
        "authors": [
            {
                "name": "Fumitaka Kimura",
                "org": ""
            },
            {
                "name": "Masahiko Gondo",
                "org": ""
            },
            {
                "name": "Norio Yamashita",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Toshiro Higuchi",
                "org": ""
            }
        ],
        "venue": "IEEE Sensors Journal",
        "year": 2010
    },
    "Ts3EKAca": {
        "id": "Ts3EKAca",
        "title": "Resolver compatible capacitive rotary position sensor",
        "abstract": "Abstract\u2014This paper,describes,a capacitive rotary,position sensor,that,is characterized,by,its high,compatibility,with commercial,resolvers. The main,components,are two,electrode plates. Both parts are composed,of simple circular or annular electrodes. The sensor is excited by two sinusoidal voltages, which are same,as the excitation voltages of resolvers. These excitation voltages are applied to the stator transmitting electrodes. Then, these voltages arise on rotor electrodes by capacitive couplings. The stator pick-up electrodes detect voltages on the rotor that are amplitude-modulated due to the capacitance,changes,depending on the rotor position. The specifications of these signals are same as those of resolvers. Therefore, the rotor position can be calculated by the same,way,as resolvers. Due to the similarities with resolvers (excitation signals, generated signals and the way of calculate positions), this sensor can easily replace a commercial resolver. In this paper, the principle is verified by a prototype sensor, which shows a non-linearity error of +/- 4 degrees.",
        "keywords": [
            "prototypes",
            "capacitive sensors",
            "electrodes",
            "capacitance"
        ],
        "authors": [
            {
                "name": "Fumitaka KIMURA",
                "org": ""
            },
            {
                "name": "Masahiko GONDO",
                "org": ""
            },
            {
                "name": "Akio YAMAMOTO",
                "org": ""
            },
            {
                "name": "Toshiro HIGUCHI",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2009
    },
    "J7id16La": {
        "id": "J7id16La",
        "title": "Development of a 2-DOF Robotic Arm Using Electrostatic Film Actuators",
        "abstract": "",
        "keywords": [
            "robot arm"
        ],
        "authors": [
            {
                "name": "Takashi NISHIJIMA",
                "org": ""
            },
            {
                "name": "Akio YAMAMOTO",
                "org": ""
            },
            {
                "name": "Toshiro HIGUCHI",
                "org": ""
            },
            {
                "name": "Akio INABA",
                "org": ""
            }
        ],
        "venue": "Journal of The Japan Society for Precision Engineering, Contributed Papers",
        "year": 2005
    },
    "yUNjR4qe": {
        "id": "yUNjR4qe",
        "title": "Voltage-induction type electrostatic film motor driven by two- to four-phase ac voltage and electrostatic induction",
        "abstract": "This paper describes a voltage-induction type electrostatic film motor that operates by feeding electric power to the slider by electrostatic induction. In the electrostatic motor, applying voltages to both of its stator and slider contributes to its fine positioning resolution and better controllability. However, in some cases such as relatively small motors, the electric wires connected to the slider could cause mechanical disturbances to the motor motion. In the new electrostatic motor, electric wires are connected only to the stator, thus the slider motion is not disturbed. The power to the slider is transferred by electrostatic induction between induction electrodes fabricated in both of the stator and the slider. The proposed motor has a two- to four-phase driving-electrode configuration, which consists of a two-phase driving electrode in the slider and a four-phase driving electrode in the stator. The paper first analyzes the thrust force characteristics of the driving-electrode configuration, and then analyzes the characteristics of voltage-induction configuration, both based on capacitance-network analysis. Experimental results showed good agreements with the analyses, confirming the feasibility of the voltage-induction type electrostatic motor.",
        "keywords": [
            "synchronous motor",
            "flexible printed circuit",
            "film actuator",
            "electrostatic induction",
            "electrostatic actuator",
            "electric power",
            "network analysis"
        ],
        "authors": [
            {
                "name": "Norio Yamashita",
                "org": ""
            },
            {
                "name": "Zu Guang Zhang",
                "org": "Department of Precision Engineering, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan"
            },
            {
                "name": "Akio Yamamoto",
                "org": "Department of Precision Engineering, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan"
            },
            {
                "name": "Masahiko Gondo",
                "org": "Department of Precision Engineering, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan"
            },
            {
                "name": "Toshiro Higuchi",
                "org": "Department of Precision Engineering, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan"
            }
        ],
        "venue": "Sensors & Actuators: A. Physical",
        "year": 2007
    },
    "X7WrBuwa": {
        "id": "X7WrBuwa",
        "title": "Tactile telepresence system using PVDF sensors and electrostatic stimulator.",
        "abstract": "",
        "keywords": [
            "tactile sensor",
            "tactile sensors",
            "control system",
            "surface roughness",
            "telerobotics",
            "linear motor",
            "surface texture",
            "virtual reality"
        ],
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Kyu Yong Kim",
                "org": ""
            },
            {
                "name": "Toshiro Higuchi",
                "org": ""
            }
        ],
        "venue": "IROS",
        "year": 2005
    },
    "Lx7c3kLq": {
        "id": "Lx7c3kLq",
        "title": "Development of a 2-DOF softness feeling display for tactile tele-presentation of deformable surfaces",
        "abstract": "",
        "keywords": [
            "force",
            "display devices",
            "degree of freedom",
            "displays",
            "control systems",
            "contact area",
            "automatic control",
            "dc motor",
            "tactile sensors",
            "dc motors"
        ],
        "authors": [
            {
                "name": "Fuminobu Kimura",
                "org": "university of tokyo"
            },
            {
                "name": "Akio Yamamoto",
                "org": "university of tokyo"
            },
            {
                "name": "Toshiro Higuchi",
                "org": "university of tokyo"
            }
        ],
        "venue": "ICRA",
        "year": 2010
    },
    "jdChfrgm": {
        "id": "jdChfrgm",
        "title": "Control of Thermal Tactile Display based on Prediction of Contact Temperature",
        "abstract": "",
        "keywords": [
            "display devices",
            "tactile sensors",
            "temperature measurement",
            "virtual environment"
        ],
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Benjamin Cros",
                "org": ""
            },
            {
                "name": "Hironori Hashimoto",
                "org": ""
            },
            {
                "name": "Toshiro Higuchi",
                "org": ""
            }
        ],
        "venue": "ICRA",
        "year": 2004
    },
    "XprX6rDK": {
        "id": "XprX6rDK",
        "title": "Development of a tactile camera for deformable surfaces",
        "abstract": "",
        "keywords": [
            "contact force",
            "haptic feedback",
            "tactile sensors",
            "virtual reality",
            "tactile sensor"
        ],
        "authors": [
            {
                "name": "kyu yong kim",
                "org": "university of tokyo"
            },
            {
                "name": "akio yamamoto",
                "org": "university of tokyo"
            },
            {
                "name": "toshiro higuchi",
                "org": "university of tokyo"
            }
        ],
        "venue": "Fertility and Sterility",
        "year": 2004
    },
    "r4ruSiJD": {
        "id": "r4ruSiJD",
        "title": "Modeling and identification of an electrostatic motor",
        "abstract": "The present study describes modeling and parameter identification for a high-power electrostatic motor. The motor is a synchronous motor with six phases that is modeled by a six-terminal capacitance network. A method to measure the capacitance coefficient matrix of a network using an LCR tester is proposed and demonstrated. The thrust force of the motor is shown analytically using the proposed model, which shows good agreement with empirical measurements of the motor behavior. Based on the proposed model, the effect of electrode skew is analyzed for force ripple reduction. Using the analysis, a skew motor is fabricated and tested, with the results demonstrating that a skewing electrode with a skew factor \u03c0 can considerably reduce thrust force ripple.",
        "keywords": [
            "parameter identification",
            "actuator",
            "ripple reduction",
            "electrostatic motor",
            "skew",
            "modeling"
        ],
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Toshiki Niino",
                "org": "Institute of Industrial Science, University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8505, Japan"
            },
            {
                "name": "Toshiro Higuchi",
                "org": "Department of Precision Engineering, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan"
            }
        ],
        "venue": "Precision Engineering",
        "year": 2006
    },
    "50JSyscw": {
        "id": "50JSyscw",
        "title": "A 2-DOF Electrostatic Sheet Conveyer using Wire Mesh for Desktop Automation",
        "abstract": "",
        "keywords": [
            "electrodes",
            "indexing terms",
            "prototypes",
            "voltage",
            "automation",
            "surface resistance"
        ],
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Hisatomo Yoshioka",
                "org": ""
            },
            {
                "name": "Toshiro Higuchi",
                "org": ""
            }
        ],
        "venue": "ICRA",
        "year": 2006
    },
    "309ZnSUC": {
        "id": "309ZnSUC",
        "title": "Development of a contact width sensor for tactile tele-presentation of softness.",
        "abstract": "",
        "keywords": [
            "prototypes",
            "optical waveguides",
            "computer graphics",
            "force",
            "tactile sensors"
        ],
        "authors": [
            {
                "name": "Fuminobu Kimura",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Toshiro Higuchi",
                "org": ""
            }
        ],
        "venue": "RO-MAN",
        "year": 2009
    },
    "IyVG4XBC": {
        "id": "IyVG4XBC",
        "title": "Non-contact Electrostatic Levitation of \u03c6400mm Silicon Wafer",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Norio Yamashita",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Toshiro Higuchi",
                "org": ""
            },
            {
                "name": "Hidehiko Yasui",
                "org": ""
            }
        ],
        "venue": "Journal of The Japan Society for Precision Engineering, Contributed Papers",
        "year": 2005
    },
    "ikkK74Jz": {
        "id": "ikkK74Jz",
        "title": "Operation of a dual excitation multiphase electrostatic drive by amplitude-modulated ac voltage",
        "abstract": "",
        "keywords": [
            "electrostatic motor",
            "electrostatic force"
        ],
        "authors": [
            {
                "name": "Toshiki Niino",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Toshiro Higuchi",
                "org": ""
            }
        ],
        "venue": "Electrical Engineering in Japan",
        "year": 2000
    },
    "I5eJ2yhW": {
        "id": "I5eJ2yhW",
        "title": "Estimation of human operational feeling level for a lever manipulation task using shoulder angle and manipulability",
        "abstract": "",
        "keywords": [
            "anthropometry",
            "ergonomics",
            "haptic interfaces",
            "manipulator kinematics",
            "medical robotics",
            "regression analysis",
            "solid modelling",
            "virtual reality",
            "3D graphic mannequin",
            "ergonomic analysis",
            "haptic lever",
            "human operational feeling level",
            "lever manipulation task",
            "limb anthropometric",
            "lock ball type lever",
            "manipulability measure",
            "multiple regression analysis",
            "shoulder angle",
            "shoulder flexion extension angle",
            "virtual environment system",
            "Human comfort and discomfort level",
            "arm kinematics",
            "haptic lever",
            "manipulability",
            "multiple regression analysis"
        ],
        "authors": [
            {
                "name": "Subrata Kumar Kundu",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Masayuki Hara",
                "org": ""
            },
            {
                "name": "Toshiro Higuchi",
                "org": ""
            }
        ],
        "venue": "SMC",
        "year": 2010
    },
    "luexRXiT": {
        "id": "luexRXiT",
        "title": "Electrostatic-motor-driven electroadhesive robot",
        "abstract": "This paper presents a new kind of climbing robots whose locomotion and adhesion are both realized by electrostatic force. Two crawler-type robots were prototyped. For both of the prototypes, high-power electrostatic film motors are installed. The slider of the electrostatic motor works as a crawling belt as well as an electrode for electroadhesion. The first prototype that has a rigid mechanical structure is light in weight (49 g) and thin in thickness (14 mm). It can climb on a vertical aluminum board with a speed up to 104 mm/s and horizontally pull a payload of about 3.2 N. The other prototype is equipped with a flexible mechanical structure that consists of a series of passive joints. By smoothly transitioning from a horizontal floor up to a slope, the robot demonstrated its capability to comply with complicated surfaces.",
        "keywords": [
            "high-power electrostatic film motors",
            "passive joints",
            "smooth transition",
            "adhesion",
            "crawling belt",
            "rigid mechanical structure",
            "legged locomotion",
            "wall climbing robots",
            "robot adhesion",
            "vertical aluminum board",
            "electrostatic motor slider",
            "crawler-type robot prototyping",
            "electrostatic-motor-driven electroadhesive robot",
            "electrodes",
            "robot locomotion",
            "flexible mechanical structure",
            "flexible manipulators",
            "horizontal floor",
            "electrostatic motors",
            "collision avoidance",
            "force",
            "adhesives",
            "films",
            "electrostatics"
        ],
        "authors": [
            {
                "name": "Hongqiang Wang",
                "org": "Dept. of Precision Eng., Univ. of Tokyo, Tokyo, Japan|c|"
            },
            {
                "name": "Akio Yamamoto",
                "org": "university of tokyo"
            },
            {
                "name": "Toshiro Higuchi",
                "org": "university of tokyo"
            }
        ],
        "venue": "IROS",
        "year": 2012
    },
    "XbzE5ut1": {
        "id": "XbzE5ut1",
        "title": "A flexible sensor measuring displacement and bending",
        "abstract": "",
        "keywords": [
            "network model"
        ],
        "authors": [
            {
                "name": "Takashi Nishijima",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Toshiro Higuchi",
                "org": ""
            }
        ],
        "venue": "Measurement Science & Technology",
        "year": 2009
    },
    "9Lhqa4CV": {
        "id": "9Lhqa4CV",
        "title": "Advanced technique for three-dimensional visualization of compound distributions in a rice kernel.",
        "abstract": "A three-dimensional (3D) visualization technique for the compound distribution in a rice kernel was developed. This technique is a combination of sectioning, staining, and digital image postprocessing. By using a special microtome system with adhesive tapes, a set of sequential sections of a rice kernel, which can be preserved with their own set of relative position data, was obtained. A single set of sequential sections was stained by various chemical techniques for the visualization of protein, starch, or lipid content. Each stained section was digitally captured using a CCD imaging device. As the stained areas represent areas containing dye-target complex, the distribution of each compound in the section was visualized in two dimensions. The digitally captured images of a single set of sequential sections were reconstructed to produce a 3D plotting image. As a result, the distributions of various compounds in a rice kernel could be visualized in a new 3D model.",
        "keywords": [
            "compound distribution",
            "three dimensional"
        ],
        "authors": [
            {
                "name": "Yukiharu Ogawa",
                "org": ""
            },
            {
                "name": "Junichi Sugiyama",
                "org": ""
            },
            {
                "name": "Heinrich Kuensting",
                "org": ""
            },
            {
                "name": "Toshio Ohtani",
                "org": ""
            },
            {
                "name": "Shoji Hagiwara",
                "org": ""
            },
            {
                "name": "Liu",
                "org": ""
            },
            {
                "name": "Mitsunori Kokubo",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Ken-ichi Kudoh",
                "org": ""
            },
            {
                "name": "Toshiro Higuchi",
                "org": ""
            }
        ],
        "venue": "Journal of agricultural and food chemistry",
        "year": 2001
    },
    "8SlIuMQ1": {
        "id": "8SlIuMQ1",
        "title": "A built-in displacement sensor for an electrostatic film motor",
        "abstract": "",
        "keywords": [
            "high frequency",
            "low frequency",
            "network model"
        ],
        "authors": [
            {
                "name": "Takashi Nishijima",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Hidehiko Yasui",
                "org": ""
            },
            {
                "name": "Toshiro Higuchi",
                "org": ""
            }
        ],
        "venue": "Measurement Science & Technology",
        "year": 2006
    },
    "D9LmgMaX": {
        "id": "D9LmgMaX",
        "title": "Development of Automated Nuclear Transplantation System.",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Nobuhiro Tsukada",
                "org": ""
            },
            {
                "name": "Ken-ichi Kudoh",
                "org": ""
            },
            {
                "name": "Michel Budiman",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Toshiro Higuchi",
                "org": ""
            },
            {
                "name": "Mamoru Kobayashi",
                "org": ""
            },
            {
                "name": "Kahei Sato",
                "org": ""
            },
            {
                "name": "Katsuaki Oishi",
                "org": ""
            },
            {
                "name": "Katsuhiko Iida",
                "org": ""
            }
        ],
        "venue": "Journal of Mammalian Ova Research",
        "year": 2001
    },
    "VOClXG5H": {
        "id": "VOClXG5H",
        "title": "Electrostatic tactile display with thin film slider and its application to tactile telepresentation systems.",
        "abstract": "A new electrostatic tactile display is proposed to realize compact tactile display devices that can be incorporated with virtual reality systems. The tactile display of this study consists of a thin conductive film slider with stator electrodes that excite electrostatic forces. Users of the device experience tactile texture sensations by moving the slider with their fingers. The display operates by applying two-phase cyclic voltage patterns to the electrodes. The display is incorporated into a tactile telepresentation system to realize explorations of remote surface textures with real-time tactile feedback. In the system, a PVDF tactile sensor and a DSP controller automatically generate voltage patterns to present surface texture sensations through the tactile display. A sensor, in synchronization with finger motion on the tactile display, scans a texture sample and outputs information about the sample surface. The information is processed by a DSP and fed back to the tactile display in real time. The tactile telepresentation system was evaluated in texture discrimination tests and demonstrated a 79 percent correct answer ratio. A transparent electrostatic tactile display is also reported in which the tactile display is combined with an LCD to realize a visual-tactile integrated display system.",
        "keywords": [
            "transparent electrostatic tactile display",
            "tactile display",
            "pvdf tactile sensor",
            "tactile telepresentation systems",
            "tactile telepresentation system",
            "remote surface texture",
            "compact tactile display device",
            "visual-tactile integrated display system",
            "new electrostatic tactile display",
            "real-time tactile feedback",
            "thin film slider",
            "device experience tactile texture",
            "electrostatic tactile display",
            "tactile sensors",
            "surface texture",
            "virtual reality",
            "real time",
            "electrostatic force",
            "thin film",
            "tactile sensor"
        ],
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": "IEEE"
            },
            {
                "name": "Shuichi Nagasawa",
                "org": ""
            },
            {
                "name": "Hiroaki Yamamoto",
                "org": ""
            },
            {
                "name": "Toshiro Higuchi",
                "org": "IEEE"
            }
        ],
        "venue": "IEEE Trans. Vis. Comput. Graph.",
        "year": 2006
    },
    "HSFxsHbz": {
        "id": "HSFxsHbz",
        "title": "Verification of the optimum electrode pitch in electrostatic capacitive type film encoder",
        "abstract": "This paper describes an optimization of a sensing-electrode-area ratio of an electrostatic capacitive type film encoder. The encoder consists of a slider film and a stator film, in each of which inducing electrodes and sensing electrodes are included. Output signals are generated by capacitors consisted between slider electrodes and stator electrodes. To obtain high accuracy, a sensing-electrode-area ratio to the electrode pitch should be optimized. In this paper, the optimum electrode ratio calculated by simulation employing the finite element method. 1. \u8af8\u3000\u3000\u3000\u8a00 \u30d5\u30a3\u30eb\u30e0\u96fb\u6975\u3092\u30bb\u30f3\u30b5\u3068\u3057\u3066\u7528\u3044\u305f\u30a8\u30f3\u30b3\u30fc\u30c0\u304c\u63d0\u6848\u3055\u308c \u3066\u3044\u308b 1).\u672c\u30a8\u30f3\u30b3\u30fc\u30c0\u306f\u9759\u96fb\u5bb9\u91cf\u5f0f\u306e\u30ea\u30cb\u30a2\u30a8\u30f3\u30b3\u30fc\u30c0\u3067, \u79fb\u52d5\u5b50\u304c\u914d\u7dda\u3092\u6301\u305f\u306a\u3044\u7279\u5fb4\u304c\u3042\u308b.\u5f93\u6765\u306e\u30a8\u30f3\u30b3\u30fc\u30c0\u306f\u30b9 \u30b1\u30fc\u30eb\u3092\u56fa\u5b9a\u3057\u3066\u30bb\u30f3\u30b5\u30d8\u30c3\u30c9\u3092\u79fb\u52d5\u3055\u305b\u308b\u65b9\u5f0f\u306e\u70ba,\u30bb\u30f3 \u30b5\u30d8\u30c3\u30c9\u5074\u3078\u306e\u914d\u7dda\u304c\u5fc5\u8981\u3067\u3042\u308b 3).\u3053\u306e\u914d\u7dda\u306f\u30bb\u30f3\u30b5\u30d8\u30c3 \u30c9\u3068\u5171\u306b\u7d76\u3048\u305a\u52d5\u304d\u7d9a\u3051\u308b\u305f\u3081,\u52d5\u4f5c\u9014\u4e2d\u3067\u65ad\u7dda\u3092\u8d77\u3053\u3057\u3066 \u3057\u307e\u3046\u61f8\u5ff5\u304c\u3042\u308b.\u305d\u3053\u3067,\u3053\u306e\u69d8\u306a\u61f8\u5ff5\u306b\u5bfe\u3057\u672c\u30a8\u30f3\u30b3\u30fc \u30c0\u304c\u958b\u767a\u3055\u308c\u305f.\u672c\u30a8\u30f3\u30b3\u30fc\u30c0\u306e\u6982\u8981\u306f\u6b21\u306e\u901a\u308a\u3067\u3042\u308b.",
        "keywords": [],
        "authors": [
            {
                "name": "Fumitaka KIMURA",
                "org": ""
            },
            {
                "name": "Masahiko GONDO",
                "org": ""
            },
            {
                "name": "Akio YAMAMOTO",
                "org": ""
            },
            {
                "name": "Toshiro HIGUCHI",
                "org": ""
            }
        ],
        "venue": "",
        "year": 0
    },
    "fASyuWCf": {
        "id": "fASyuWCf",
        "title": "Experimental evaluation of open-loop swimming control for a robotic fish using electrostatic film motors",
        "abstract": "We have developed an underwater robotic fish using a unique three-layer electrostatic film motor. In the robotic fish, the unique motor actuates a flexible caudal fin to propel the robot via an elaborate power transmission system. In the present study, we describe the major disadvantages of the previous prototype of the robotic fish and improvements of the prototype. In addition, we present experimental evaluations related to the control parameters and locomotion performance of the robotic fish. These control parameters include the frequency and initial phase of AC voltage, and the amplitude and period of frequency sweeping. A simple theoretical model concerning the power transmission system of the robotic fish is also analyzed to provide a possible explanation for the unique swimming control. By appropriately adjusting these control parameters, we achieve cruising, emerging, submerging, and turning of the robotic fish even though only the caudal fin is active. Finally, we show smooth human-operated turn-around motion similar to that seen in real fish. Based on these experimental results, we further clarify the relationships between the open-loop motor pattern and motion parameters.",
        "keywords": [
            "open-loop motor pattern",
            "real fish",
            "robotic fish",
            "unique three-layer electrostatic film",
            "experimental evaluation",
            "electrostatic film motor",
            "caudal fin",
            "unique swimming control",
            "unique motor",
            "underwater robotic fish",
            "control parameter",
            "open-loop swimming control",
            "elaborate power transmission system"
        ],
        "authors": [
            {
                "name": "Norio Yamashita",
                "org": "Department of pricision engineering, graduate school of engineering, the university of tokyo, tokyo, japan"
            },
            {
                "name": "Zu guang Zhang",
                "org": "Department of mechanical engineering, faculty of science and technology, tokyo university of science, 2641 yamazaki, noda, chiba 278-8510, japan"
            },
            {
                "name": "Akio Yamamoto",
                "org": "Department of pricision engineering, graduate school of engineering, the university of tokyo, tokyo, japan"
            },
            {
                "name": "Masahiko Gondo",
                "org": "Seidensha corporation, sic-2-404, 5-4-21 nishi-hashimoto, sagamihara, kanagawa, japan"
            },
            {
                "name": "Toshiro Higuchi",
                "org": "Department of pricision engineering, graduate school of engineering, the university of tokyo, tokyo, japan"
            }
        ],
        "venue": "Robotica",
        "year": 2010
    },
    "JnLUrH3s": {
        "id": "JnLUrH3s",
        "title": "High-Power, Double-Sided Drive Type Electrostatic Motor with Stacked-Film Structure",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Akio YAMAMOTO",
                "org": ""
            },
            {
                "name": "Takashi NISHIJIMA",
                "org": ""
            },
            {
                "name": "Toshiro HIGUCHI",
                "org": ""
            },
            {
                "name": "Akio INABA",
                "org": ""
            }
        ],
        "venue": "Journal of The Japan Society for Precision Engineering, Contributed Papers",
        "year": 2005
    },
    "gTUOqz1v": {
        "id": "gTUOqz1v",
        "title": "An electrostatic induction actuator for dielectric sheet conveying",
        "abstract": "",
        "keywords": [
            "electric fields",
            "electrodes",
            "surface resistance",
            "dielectric materials",
            "induction motor",
            "dielectrics",
            "induction motors",
            "electrostatics",
            "force"
        ],
        "authors": [
            {
                "name": "mehdi modabberifar",
                "org": "arak university"
            },
            {
                "name": "akio yamamoto",
                "org": "university of tokyo"
            },
            {
                "name": "toshiro higuchi",
                "org": "university of tokyo"
            }
        ],
        "venue": "Ai Magazine",
        "year": 2010
    },
    "zrbjqF8p": {
        "id": "zrbjqF8p",
        "title": "Interaction force estimation on a built-in position sensor for an electrostatic visuo-haptic display",
        "abstract": "This paper discusses a force sensing method using a built-in position sensing system for an electrostatic visuo-haptic display. The display provides passive haptic feedback on a flat panel visual monitor, such as LCD, using electrostatic friction modulation via multiple contact pads arranged on a surface-insulated transparent electrode. The display demonstrated in previous studies measured the positions of the pads in a similar manner to surface-capacitive touch-screens. This paper extends the sensor such that the system can monitor the electrostatic interaction force provided to the contact pads. The extension is realized by estimating the capacitance between the contact pads and the display surface. The paper investigates its basic characteristics to show that the force estimation is possible, regardless of the pad positions and the pushing force exerted by users. The force estimation capability is used for feedback control of interaction force, which improves the accuracy of the interaction force. The paper further extends the method such that the system can detect the moving direction of contact pads. By dividing the electrode of a contact pad and comparing their capacitances, the system can detect in which direction the user is trying to move the pad. Such capability is effective for solving the sticky-wall problem, which is known to be a common problem in passive haptic systems. A pilot experiment shows that the proposed system can considerably reduce the sticky-wall effect.",
        "keywords": "",
        "authors": [
            {
                "name": "Taku Nakamura",
                "org": "Department of Presicion Engineering, The University of Tokyo, Tokyo, Japan"
            },
            {
                "name": "Akio Yamamoto",
                "org": "Department of Presicion Engineering, The University of Tokyo, Tokyo, Japan"
            }
        ],
        "venue": "ROBOMECH Journal",
        "year": 2016
    },
    "B0WMjxmF": {
        "id": "B0WMjxmF",
        "title": "Modeling and control of electroadhesion force in DC voltage",
        "abstract": "In this paper, a new model for electroadhesion between two surface-insulated plates under DC electric field is presented and control of dynamic responses of electroadhesion force is discussed. Under DC electric field, even if the voltage difference between the plates is constant, electroadhesion force increases or decreases over time depending on the insulating materials. The increase had been explained by Johnsen\u2013Rahbek (JR) model, but the decrease had not been focused or modeled by physically meaningful way. In addition, the previous models did not explicitly consider the mechanical behaviors of the electrodes, although the mechanical behaviors considerably affect the response. In this work, we introduced a new model that combines both electrical and mechanical behaviors. The electrical part, which is based on JR model, explained the force decrease under DC field, in addition to the force increase that had been explained using JR model. The mechanical part was represented by a combination of a spring and a damper. Numerical simulations using the model successfully reproduced characteristics behaviors of electroadhesion force, which include force decay under constant voltages and relatively smaller initial force. Using the inverse model, we carried out experiments to control dynamic responses of electroadhesion force, which successfully controlled force responses against pulse voltages. Through the experiments, we also showed the importance of the neutralization of surface charges for obtaining reproducible responses.",
        "keywords": [
            "Electrostatic adhesion",
            " Bilayer dielectric",
            " Interface charge",
            " Johnsen\u2013Rahbek effect",
            " Built-in sensor",
            " Haptic display"
        ],
        "authors": [
            {
                "name": "Taku Nakamura",
                "org": "Department of Precision Engineering, The University of Tokyo, Tokyo, Japan"
            },
            {
                "name": "Akio Yamamoto",
                "org": "Department of Precision Engineering, The University of Tokyo, Tokyo, Japan"
            }
        ],
        "venue": "ROBOMECH Journal",
        "year": 2017
    },
    "GCLxZeDj": {
        "id": "GCLxZeDj",
        "title": "Performance of displayed-marker-based position tracking",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": "Department of Precision Engineering, The University of Tokyo"
            },
            {
                "name": "Taku Nakamura",
                "org": "Department of Precision Engineering, The University of Tokyo"
            }
        ],
        "venue": "Journal of Advanced Mechanical Design Systems and Manufacturing",
        "year": 2018
    },
    "EOxcjiPW": {
        "id": "EOxcjiPW",
        "title": "Peel Force of Electrostatic Adhesion in Crawler-type Electrostatic Climbing Robots",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Hongqiang Wang",
                "org": "The University of Tokyo"
            },
            {
                "name": "Akio Yamamoto",
                "org": "The University of Tokyo"
            }
        ],
        "venue": "Journal of the Japan Society of Applied Electromagnetics and Mechanics",
        "year": 2015
    },
    "EmVGITtz": {
        "id": "EmVGITtz",
        "title": "Statistical bias correction for climate change impact on the basin scale precipitation in Sri Lanka, Philippines, Japan and Tunisia",
        "abstract": "Abstract.  We introduce a 3-step statistical bias correction method to solve global climate model (GCM) bias by determining regional variability through multi-model selection. This is a generalized method to assess imperfect GCMs that are unable to simulate distinct regional climate characteristics, either spatially or temporally. More remaining local bias is eliminated using an all-inclusive statistical bias correction addressing the major shortcomings of GCM precipitation. First, the multi-GCM choice is determined according to spatial correlation (Scorr) and root mean square error (RMSE) of regional and mesoscale climate variation in a comparison with global references. After multi-GCM selection, there are three major steps in the proposed bias correction, i.e., the generalized Pareto distribution (GPD) for extreme rainfall bias correction, ranking order statistics for wet and dry day frequency errors, and a two-parameter gamma distribution for monthly normal rainfall bias correction. Best-fit GPD parameters are resolved by the RMSE, a Hill plot, and mean excess function. The capability of the method is examined by application to four catchments in diverse climate regions. These are the Kalu Ganga (Sri Lanka), Pampanga, Angat and Kaliwa (Philippines), Yoshino (Japan), and Medjerda (Tunisia). The assumption of GCM stationary error in the future is verified by calibration in 1981\u20132000 and validation over 1961\u20131980 at two observation sites. The results show a favorable outcome. Overall performance of catchments was good for bias-corrected extreme events and inter-seasonal climatology, compared with observations. However, the suggested method has no intermediate grid scale between the GCM grid and observation points, and requires a well-distributed observed rain gauge network to reproduce a reasonable rainfall distribution over a target basin. The results of holistic bias correction provide reliable, quantitative and qualitative information for basin or national scale integrated water resource management.",
        "keywords": "",
        "authors": [
            {
                "name": "Cho Thanda Nyunt",
                "org": "Department of Civil and Environmental Engineering, Hiroshima University, Hiroshima, Japan"
            },
            {
                "name": "Toshio Koike",
                "org": "Department of Civil Engineering, The University of Tokyo, Tokyo, Japan"
            },
            {
                "name": "Akio Yamamoto",
                "org": "Institute of Industrial Science, The University of Tokyo, Tokyo, Japan"
            }
        ],
        "venue": "Hydrology and Earth System Sciences Discussions",
        "year": 2016
    },
    "0fgGShtl": {
        "id": "0fgGShtl",
        "title": "Dielectric oil-based polymer actuator for improved thickness strain and breakdown voltage",
        "abstract": "Dielectric elastomer actuators (DEAs) have been increasingly investigated as alternative actuators to conventional ones. However, DEAs suffer from high rates of premature failure. Therefore, this study proposes a dielectric oil-based polymer actuator, also called a Dielectric liquid actuator (DLA), to compensate for the drawbacks of DEAs. DLA was experimentally compared with conventional DEAs. Results showed that DLA successfully prevented thermal runaway at defects in the electrode and excessive thinning of the film, resulting in increased breakdown voltage. Consequently, premature failure was inhibited, and the performance was improved. The breakdown voltages of DLA and DEA were 6000 and 2000 V, respectively, and their maximum thickness strains were 49.5% and 37.5%, respectively.",
        "keywords": "",
        "authors": [
            {
                "name": "Minsung Cho",
                "org": "The University of Tokyo"
            },
            {
                "name": "Akio Yamamoto",
                "org": "The University of Tokyo"
            }
        ],
        "venue": "Journal of Mechanical Science and Technology",
        "year": 2016
    },
    "9UiSIbbf": {
        "id": "9UiSIbbf",
        "title": "Toward self-sensing of an electrostatic film motor using driving currents",
        "abstract": "Several kinds of exclusive displacement sensor systems have been proposed for electrostatic film motors, to fully profit from their thin and flexible structures. The existing sensor systems share the same underlying principle, which utilizes a multi-phase high frequency sensing signal to realize the robust and precise displacement sensing. However, high frequency oscillators and amplifiers are required in them, which can increase the complexity of the motor system. This paper proposes a new method to estimate the slider position for the electrostatic film motors based on the characteristics of the motor itself. The proposed method has lower sensing resolution than previous sensor systems, but it can be realized in a much simpler way, contributing to the simple system structure. The displacement will be estimated directly from the driving voltages and currents, by which the sensing system can be simplified. This paper focuses on a synchronous-type motor and analyzes its current characteristics during synchronous operation in theory, based on the capacitance network model of the typical electrostatic film motor. From the theoretical results, it has been known that pulse signals in current features, which can be obtained by removing base waves of the source currents, correspond to the stepwise motion. Because pulse signals change periodically, a new pulse train can be obtained by adding the absolute values of these current features. The slider position can be calculated with a resolution of the electrode pitch, by counting the number of pulse signals in pulse train after binarization. A verification experiment has been done, which has shown that the slider position can be estimated by the proposed method with a resolution of the electrode pitch.",
        "keywords": "",
        "authors": [
            {
                "name": "Guangwei Zhang",
                "org": "Department of Precision Engineering, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan"
            },
            {
                "name": "Akio Yamamoto",
                "org": "Department of Precision Engineering, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan"
            }
        ],
        "venue": "international conference on industrial technology",
        "year": 2018
    },
    "9urp4xna": {
        "id": "9urp4xna",
        "title": "Prototyping a thermal walker that can walk on a hot horizontal surface with a simple gait",
        "abstract": "This article reports on a newly designed thermal walker that can walk on a hot horizontal surface without any motor or battery. The walker converts heat energy from the hot surface into mechanical motion by using bimetal sheets. The prototype developed in the previous study successfully demonstrated walking, but its gait was not ideal; a leg swings forward and backward a few times to achieve one step. This article designs a new walker to realize more natural walking, in which a leg simply swings forward once in each step. For this purpose, the article introduces a new design process to better estimate the swing period. Also, material used for the feet of the walker is reconsidered to realize stable continuous walking. The newly fabricated prototype has aluminum feet and can walk on a hot horizontal surface with the simple gait. The surface temperature required for walking was 110\u2009\u00b0C, which was considerably lowered from that in the previous study, which was 170\u2009\u00b0C.",
        "keywords": [
            "Bimetal",
            " Thermal deformation",
            " Environmental heat",
            " Passive dynamic walker",
            " Thermal",
            " Walker"
        ],
        "authors": [
            {
                "name": "Takeru Nemoto",
                "org": "Department of Precision Engineering, The University of Tokyo, Tokyo, Japan"
            },
            {
                "name": "Akio Yamamoto",
                "org": "Department of Precision Engineering, The University of Tokyo, Tokyo, Japan"
            }
        ],
        "venue": "ROBOMECH Journal",
        "year": 2018
    },
    "rUzgtvYz": {
        "id": "rUzgtvYz",
        "title": "Sensorless displacement estimation for an electrostatic film motor using driving currents",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Guangwei Zhang",
                "org": ", The University of Tokyo, , Japan"
            },
            {
                "name": "Akio Yamamoto",
                "org": ", The University of Tokyo, , Japan"
            }
        ],
        "venue": "International Journal of Applied Electromagnetics and Mechanics",
        "year": 2019
    },
    "EeWh1eHh": {
        "id": "EeWh1eHh",
        "title": "A trial fabrication of micro structures by ultra precision cutting",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Yutaka Yamagata",
                "org": "KAST"
            },
            {
                "name": "Shin-Ya Morita",
                "org": "University of Tokyo"
            },
            {
                "name": "Toshiki Niino",
                "org": "RIKEN"
            },
            {
                "name": "Akio Yamamoto",
                "org": "University of Tokyo"
            },
            {
                "name": "Toshiro Higuchi",
                "org": "University of Tokyo"
            }
        ],
        "venue": "Ieej Transactions on Sensors and Micromachines",
        "year": 1997
    },
    "2Yd8beTq": {
        "id": "2Yd8beTq",
        "title": "Tactile Display using Thin Type Electrostatic Linear Actuator",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Toshiki Ishii",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Toshiro Higuchi",
                "org": ""
            }
        ],
        "venue": "Ieej Transactions on Sensors and Micromachines",
        "year": 2002
    },
    "qwBcavn8": {
        "id": "qwBcavn8",
        "title": "Thermal Tactile Presentation Based on Prediction of Contact Temperature.",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Hiroaki Yamamoto",
                "org": ""
            },
            {
                "name": "Benjamin Cros",
                "org": ""
            },
            {
                "name": "Hironori Hashimoto",
                "org": ""
            },
            {
                "name": "Toshiro Higuchi",
                "org": ""
            }
        ],
        "venue": "JRM",
        "year": 2006
    },
    "WykwZE7A": {
        "id": "WykwZE7A",
        "title": "Proposal of High Performance 1.55 \u00b5m Quantum Dot Heterostructure Laser Using InN.",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Md. Mottaleb Hossain",
                "org": ""
            },
            {
                "name": "Md. Abdullah-Al Humayun",
                "org": ""
            },
            {
                "name": "Md. Tanvir Hasan",
                "org": ""
            },
            {
                "name": "Ashraful Ghani Bhuiyan",
                "org": ""
            },
            {
                "name": "Akihiro Hashimoto",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "IEICE Transactions",
        "year": 2012
    },
    "Z0W4W8Lm": {
        "id": "Z0W4W8Lm",
        "title": "Phase separation of thick (\u223c1 \u00b5m) In",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "akio yamamoto",
                "org": ""
            },
            {
                "name": "md tanvir hasan",
                "org": ""
            },
            {
                "name": "akihiro mihara",
                "org": ""
            },
            {
                "name": "norihiko narita",
                "org": ""
            },
            {
                "name": "naoteru shigekawa",
                "org": ""
            },
            {
                "name": "masaki kuzuhara",
                "org": ""
            }
        ],
        "venue": "Applied Physics Express",
        "year": 2014
    },
    "TwNp0uVu": {
        "id": "TwNp0uVu",
        "title": "Latest progress in the MOVPE growth of indium nitride (InN) film (\u5c0f\u7279\u96c6\u30c6\u30fc\u30de:\u9032\u5c55\u3059\u308b\u7a92\u5316\u7269\u534a\u5c0e\u4f53\u5149\u30fb\u96fb\u5b50\u30c7\u30d0\u30a4\u30b9\u306e\u73fe\u72b6)",
        "abstract": "",
        "keywords": [
            "afm",
            "inn"
        ],
        "authors": [
            {
                "name": "ashraful g bhuiyan",
                "org": ""
            },
            {
                "name": "akihiro hashimoto",
                "org": ""
            },
            {
                "name": "akio yamamoto",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2002
    },
    "QhiRu6EC": {
        "id": "QhiRu6EC",
        "title": "Platinum-catalyst-assisted metalorganic vapor phase epitaxy of InN",
        "abstract": "This paper reports the first attempt of the Pt-catalyst-assisted MOVPE growth of InN. In order to enhance NH 3 decomposition at a relatively low growth temperature (\u223c550 \u00b0C), Pt is used as a catalyst. The catalyst is installed in the NH 3 introduction tube in the MOVPE reactor and the tube is located just above the susceptor to be heated. Compared with InN films grown without the catalyst, the samples grown with Pt catalyst show improved electrical properties; a carrier concentration in the order of 10 18 cm \u22123 and a Hall mobility as high as 1350 cm 2 /Vs are obtained. The crystalline quality is also improved by employing the catalyst and a tilt fluctuation as low as 8.6 arcmin is obtained for a sample grown on a GaN/sapphire template. It is confirmed that for InN films grown at 550 \u00b0C with Pt catalyst, the electrical and crystallographic properties are also improved with increase in thickness. These results indicate that the growth at around 550 \u00b0C with the Pt catalyst is performed under the circumstances where NH 3 is effectively decomposed, whereas the deterioration of InN during growth is significantly suppressed. Keywords A1. Metalorganic chemical vapor deposition B1. Nitrides B2. Semiconducting indium compounds 1 Introduction Indium nitride (InN) has attracted much attention because of its potential application for optical and electronic devices [1] . This material has a direct band gap of about 0.65 eV, which is suitable for the long-wavelength optical-communication devices. It is also attracted as a material for high-speed electron devices because a room-temperature electron mobility as high as 14,000 cm 2 /Vs is theoretically predicted for InN [2] . In addition, InN-based ternary alloys, InGaN and InAlN, are promising for high-efficiency multi-junction tandem solar cells, because the band gap energy can be continuously varied with composition to cover the full solar spectrum region. For the device applications described above, it will be required to develop a growth technology on a mass-production scale in the future. For many compound semiconductor devices, MOVPE has been widely employed as a growth method with a mass-production capability. Regarding InN growth, however, the present MOVPE technology provides only poor quality InN compared with the MBE samples [3,4] . The quality of MBE-grown InN has been considerably improved in these 5 years. For example, a carrier concentration in the order of 10 17 cm \u22123 and an electron mobility higher than 2000 cm 2 /Vs have been realized. The preparation of thick films greatly contributes to the improvement of the quality of MBE-grown InN [3] . For MOVPE-grown InN, on the other hand, such an improvement of film quality by increasing its thickness has not been observed. The quality of MOVPE InN is rather deteriorated with increase in its thickness [5] . Through a systematic study on the crystallographic and electrical/optical properties of atmospheric pressure MOVPE InN films, we have recently elucidated the factors obstructing the improvement of MOVPE InN quality [6] . The main conclusion of the study is that there is a dilemma against growth temperature; at a low growth temperature around 550 \u00b0C, a low thermal decomposition rate of NH 3 causes the formation of N vacancies in grown InN, resulting in a high residual carrier concentration, while InN films grown at 600 \u00b0C or higher are deteriorated during growth, resulting in increased FWHM of X-ray rocking curve and poor electrical properties. An important remark is that the deterioration does not occur at around 550 \u00b0C. From these results, therefore, we arrived at an important conclusion that the employment of a method to enhance NH 3 decomposition at a relatively low temperature (\u223c550 \u00b0C) can solve such a dilemma. This paper reports the first attempt of Pt-catalyst-assisted MOVPE of InN. It is well known that the platinum-group metals effectively decompose NH 3 [7] . Such catalysts are widely used to generate H 2 from NH 3 . It has been also reported that decomposition products such as NH 2 , NH and N are effectively produced in the catalytic decomposition process of NH 3 [8] . Such species are believed to be useful for the nitride growth. In this paper, the crystallographic and electrical characterizations of InN films grown using Pt catalyst at around 550 \u00b0C are made and the effectiveness of the catalyst is described. 2 Experimental An MOVPE system with a horizontal reactor is employed in this study. A schematic drawing of the reactor used is shown in Fig. 1 . The horizontal reactor is designed to install Pt wires (0.5 mm \u03d5 ) as catalyst in the NH 3 introduction tube. The carbon susceptor in the reactor is RF-heated. Since the NH 3 introduction tube is in contact with the susceptor surface, the catalyst is heated by both conduction and radiation from the susceptor. Although the temperature of the catalyst has not been measured, it seems to be considerably lower than that of the susceptor. Sapphire (0 0 0 1) wafers and GaN/sapphire (0 0 0 1) templates are used for substrates. When sapphire substrate is used, a 20-nm-thick GaN layer grown at 550 \u00b0C is used as a buffer. Just before the InN growth, the GaN buffer is annealed at 1000 \u00b0C for a few minutes. Then, an InN layer is grown at a temperature in the range 525\u2013600 \u00b0C. Thus, the Pt-cracked NH 3 is used for the growth and annealing of the GaN buffer as well as the InN growth. GaN/sapphire templates used here are prepared by the conventional MOVPE without Pt catalyst. An InN layer is also grown on GaN/sapphire template using the Pt-cracked NH 3 . No buffers are used in this case. Electrical properties are measured with the van der Pauw Hall measurement. Crystalline quality is evaluated by X-ray diffraction and Raman scattering. 3 Results and discussion Fig. 2 shows the growth temperature dependence of carrier concentration and the Hall mobility for InN films grown with or without Pt catalyst. As can be seen in this figure, carrier concentrations for the samples grown with the catalyst are reduced and those in the order of 10 18 cm \u22123 are attained for the samples grown at 550\u2013600 \u00b0C. It is noted that the reduction in carrier concentration is larger for samples grown at lower temperatures, that is the effect of the catalyst is more remarkable at lower growth temperatures. Electron mobility is also increased by employing the catalyst and the sample grown at 575 \u00b0C using Pt catalyst shows the highest mobility. The improvement of electrical properties for InN grown at a low temperature (550 \u00b0C) indicates that decomposition products of NH 3 , such as NH 2 and NH, are effectively produced by the assistance of the catalyst [8] and they effectively contribute to InN growth. Fig. 3 shows the film thickness dependence of the Hall mobility of InN film grown using Pt catalyst. As can be seen, mobility is increased with increase in thickness and a high mobility 1350 cm 2 /Vs is obtained for a film with a thickness of 0.7 \u03bcm. When an InN film is grown at 600 \u00b0C or higher temperature, on the other hand, mobility is decreased with increase in thickness [6] . This is due to the deterioration of InN during growth. The result shown in Fig. 3 shows that the deterioration is suppressed by employing a low growth temperature (550 \u00b0C). Fig. 4 shows the relationships between a- and c-lattice parameters measured for InN films grown with or without the catalyst. The c- and a-lattice parameters are estimated from the \u03c9 \u22122 \u03b8 scans along the symmetric (0 0 0 2) and the asymmetric (10\u201311) reflexes, based on the assumption that InN layers are perfectly relaxed. The lines in Fig. 4 show the expected changes in c- and a-lattice parameters for InN under biaxial and hydrostatic strains [9] . One can see that all samples prepared here have a compressive strain. Both parameters for the sample grown with the catalyst at 550 \u00b0C are larger than those for the sample grown at the same temperature without Pt. They are rather similar to those for a sample grown at 600 \u00b0C without Pt [6] . The increase in both parameters and their approaches to the stoichiometric value indicate the reduction of nitrogen vacancies in the film grown with Pt. Fig. 5 shows the typical (0 0 0 2) rocking curves for InN grown on a GaN/sapphire template and a GaN buffer layer on sapphire. They are obtained with a double crystal X-ray diffraction system using 10 mm\u00d71 mm slit. The InN samples are grown at 550 \u00b0C with Pt catalyst. The film grown on the GaN template shows a very small FWHM 8.6 arcmin, while that grown on the GaN buffer shows 23 arcmin. Thus, a film with excellent crystallinity is grown on the template. Fig. 6 shows the thickness dependence of FWHM of (0 0 0 2) XRC (tilt fluctuation). The FWHM values of samples grown at 600 \u00b0C are markedly increased with increase in thickness, as can be seen in this figure. This is an evidence for the deterioration of these samples during growth. For InN films grown with Pt catalyst at 550 \u00b0C using a GaN buffer, on the other hand, the FWHM values are decreased with increase in thickness. Such improvement of the MOVPE InN quality with the increase in thickness is due to the suppressed deterioration of grown InN. As described in the experimental section, the Pt-cracked NH 3 is used in the growth and annealing of the buffer as well as in the InN layer growth. One can see that no differences are found between the tilt fluctuation values for relatively thin (\u223c0.2 \u03bcm) InN grown with and without Pt-catalyst. This indicates that the effect of the Pt cracking of NH 3 on the buffer quality is not significant. The InN films grown on a GaN template show an unexpected thickness dependence different from those grown on GaN buffer. The FWHM values for these films are considerably small and show a little increase in FWHM with increase in thickness. We need more characterization to explain this behavior. Residual stress in the films seems to be related with this unexpected behavior. Fig. 7 shows the growth temperature dependence of FWHM of E 2 high Raman peak. The conventional samples grown without Pt catalyst show the minimum FWHM at around 620 \u00b0C [6] . The samples grown with Pt show a different behavior, that is FWHM shows a very small value at around 550 \u00b0C and then gradually increases with increase in growth temperature. Thus, the Raman data also clearly show that the film grown with Pt at 550 \u00b0C has very excellent crystalline quality. We also have to clarify the reason for the difference in the growth temperature dependence between the conventional and the Pt-catalyst-assisted samples. Fig. 8 shows a photoluminescence (PL) spectrum for an InN film (0.4 \u03bcm thick) grown on a GaN buffer at 575 \u00b0C with Pt catalyst. The peak is located at around 0.7 eV, which is typical for the narrow-gap InN grown by MBE [10] and MOVPE [11] . 4 Conclusion We have proposed the Pt-catalyst-assisted MOVPE of InN for the first time. The effectiveness of the employment of the catalyst in growing higher quality InN is clearly demonstrated. InN films grown with Pt catalyst at around 550 \u00b0C show improved electrical properties compared with the samples grown without the catalyst. A carrier concentration in the order of 10 18 cm \u22123 and a Hall mobility higher than 1300 cm 2 /Vs are obtained. The crystalline quality is also improved by employing Pt catalyst. A very low tilt fluctuation, 8.6 arcmin, is obtained for a sample grown with the catalyst on a GaN/sapphire template. The improvement in electrical and crystallographic properties of InN with increase in InN thickness is also confirmed for InN films grown with Pt catalyst at around 550 \u00b0C. These results indicate that the growth with the Pt catalyst is performed under the circumstances where the sufficient amount of the decomposition species such as NH 2 is produced and the deterioration of InN during growth is suppressed. At present, the growth conditions for InN, including catalyst metal selection, have not been optimized yet. Further improvement of InN quality will be achieved by optimizing them. Acknowledgements The authors thank Prof. H. Harima and Mr. J.G. Kim, Kyoto Institute of Technology, Japan, for Raman scattering measurement. This work was partly supported by the Ministry of Education, Culture, Sports, Science and Technology of Japan through Grant-in-Aid for Scientific Research in Priority Areas \u201c Optoelectronics Frontier by Nitride Semiconductor\u2014Ultimate Utilization of Nitride Semiconductor Material Potential \u201d (no. 18069005 ). References [1] A.G. Bhuiyan A. Hashimoto A. Yamamoto J. Appl. Phys. 94 2003 2779 [2] V.M. Polyakov F. Schwierz Appl. Phys. Lett. 88 2006 032101 [3] J. Wu W. Walukiewicz S.X. Li R. Armitage J.C. Ho E.R. Weber E.E. Haller H. Lu W.J. Schaff Appl. Phys. Lett. 84 2004 2805 [4] X. Wang S.-B. Che Y. Ishitani A. Yoshikawa Appl. Phys. Lett. 90 2007 151901 [5] H. Miwa A. Hashimoto A. Yamamoto Phys. Status Solidi (c) 3 2006 1536 [6] A. Yamamoto K. Sugita A. Hashimoto J. Cryst. Growth 311 2009 4636 [7] S.F. Yin B.Q. Xu X.P. Zhou C.T. Au Appl. Catal. A: General 277 2004 1 [8] M.C.J. Bradford P.E. Fanning M.A. Vannice J. Catal. 172 1997 479 [9] A. Kadir T. Ganguli R. Kumar M.R. Gokhale A.P. Shah S. Ghosh B.M. Arora A. Bhattacharya Appl. Phys. Lett. 91 2007 111913 [10] Y.-Z. Yao T. Sekiguchi N. Ohashi Y. Adachi T. Ohgaki Appl. Phys. Lett. 92 2008 211910 [11] A. Yamamoto H. Miwa W.W. Wang A. Hashimoto Phys. Status Solidi (a) 203 2006",
        "keywords": [],
        "authors": [
            {
                "name": "Kohei Sasamoto",
                "org": "Graduate School of Engineering, University of Fukui, 3-9-1 Bunkyo, Fukui 910-8507, Japan"
            },
            {
                "name": "Ken-ichi Sugita",
                "org": "Graduate School of Engineering, University of Fukui, 3-9-1 Bunkyo, Fukui 910-8507, Japan"
            },
            {
                "name": "Akihiro Hashimoto",
                "org": "Graduate School of Engineering, University of Fukui, 3-9-1 Bunkyo, Fukui 910-8507, Japan"
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "Journal of Crystal Growth",
        "year": 2011
    },
    "7hxiDKwj": {
        "id": "7hxiDKwj",
        "title": "Design and performance of 1.55 \u03bcm laser using InGaN",
        "abstract": "",
        "keywords": [
            "design",
            "performance",
            "laser",
            "modeling"
        ],
        "authors": [
            {
                "name": "Md. Tanvir Hasan",
                "org": ""
            },
            {
                "name": "Md. Jahirul Islam",
                "org": ""
            },
            {
                "name": "Rajib-ul-Hasan",
                "org": ""
            },
            {
                "name": "Md. Sherajul Islam",
                "org": ""
            },
            {
                "name": "Shahrina Yeasmin",
                "org": ""
            },
            {
                "name": "Ashraful G. Bhuiyan",
                "org": ""
            },
            {
                "name": "Md Rafiqul Islam",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "Physica Status Solidi (c)",
        "year": 2010
    },
    "lI43onzc": {
        "id": "lI43onzc",
        "title": "Nitridation of InAs(100) surface in a flowing NH3: formation of InNAs?",
        "abstract": "Wafers of InAs(1 0 0) have been annealed in a flowing NH 3 at a temperature in the range of 450\u2013600\u00b0C. No significant differences in RHEED patterns are found among samples without annealing and those annealed at 450\u2013600\u00b0C. XPS analysis shows the presence of nitrogen only for wafer surfaces nitrided at 450\u2013500\u00b0C. In concert with the appearance of the N peak, both In 3d and As 3d spectra for the samples annealed at 450\u2013500\u00b0C have a new peak. These results show that new compounds containing N, In and As are formed when the surface is annealed at 450\u2013500\u00b0C. Candidates including InNAs for the newly formed materials have been discussed. Formation of a mixture of AsN x and metallic In seems to be most probable. PACS 68.35.Dv 81.60.Cp Keywords InAs Nitridation XPS analysis InNAs",
        "keywords": [],
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Tomohiro Shin-ya",
                "org": "Faculty of Engineering, Fukui University, 3-9-1 Bunkyo, Fukui 910, Japan"
            },
            {
                "name": "Toshimitsu Sugiura",
                "org": "Faculty of Engineering, Fukui University, 3-9-1 Bunkyo, Fukui 910, Japan"
            },
            {
                "name": "Mitsugu Ohkubo",
                "org": "Faculty of Engineering, Fukui University, 3-9-1 Bunkyo, Fukui 910, Japan"
            },
            {
                "name": "Akihiro Hashimoto",
                "org": "Faculty of Engineering, Fukui University, 3-9-1 Bunkyo, Fukui 910, Japan"
            }
        ],
        "venue": "Journal of Crystal Growth",
        "year": 1998
    },
    "XNiNQu9a": {
        "id": "XNiNQu9a",
        "title": "The most possible donor in InN grown by metalorganic vapor-phase epitaxy",
        "abstract": "This paper reports the electrical and optical properties of InN films grown by conventional metalorganic vapor-phase epitaxy (MOVPE) and laser-assisted MOVPE (LA-MOVPE) using an ArF excimer laser. On the basis of these properties, the most plausible donor in MOVPE InN is discussed. The carrier concentration for MOVPE InN decreases with increasing NH 3 /TMI molar ratio even when growth proceeds under a N-rich environment, suggesting that either a substitutional impurity at N sites or a N-vacancy related defect serves as the donor in MOVPE InN. The LA-MOVPE samples reveal that oxygen can be easily incorporated into InN. It is concluded that the most probable donor candidate for MOVPE InN is oxygen. Incorporation of oxygen into InN decreases with increasing growth pressure and temperature. The reduced oxygen level for InN grown at high temperature is presumably due to the volatility of In\u2013O compounds. The best data obtained for MOVPE InN are a carrier concentration of 4.7 \u00d7 10 18 cm \u2212 3 and a mobility of 1100 cm 2 /Vs. InN film quality can be further improved by reducing the amount of oxygen being incorporated into the growing InN. Keywords Indium nitride Chemical vapor deposition Electrical properties and measurements 1 Introduction Until very recently, indium nitride (InN) attracted attention only as a constituent of GaInN and AlInN alloys. The predicted low effective mass and high saturation velocity for electrons in InN [1,2] have boosted interest in InN as a highly promising material for high-speed electronic devices. Significant improvements have been achieved in the growth of InN films recently by using molecular beam epitaxy (MBE) and metalorganic vapor-phase epitaxy (MOVPE). These developments have revealed the actual band gap energy of InN to be about 0.7 eV at room temperature [3\u20135] . However, no InN-based devices have been constructed to date. This requires further studies on their growth and characterization. In the case of compound semiconductors, MOVPE has been the most widely used growth technique for both research and device production. Compared with MBE-grown InN, however, the quality of MOVPE InN is relatively poor at present: it yields a higher residual carrier concentration and a lower electron mobility. A carrier concentration of 6 \u00d7 10 18 cm \u2212 3 [6] and a Hall mobility of 870 cm 2 /Vs [7] are the best data obtained for MOVPE InN. The lowest carrier concentration for MOVPE InN is still higher than the values reported for MBE InN, namely 3 \u00d7 10 17 \u20132 \u00d7 10 18 cm \u2212 3 [8\u201312] . The most essential issue for the improvement of MOVPE-grown InN is to find the main donor and reduce its level. Several candidates for donors such as nitrogen vacancies, oxygen, hydrogen or structural defects have been considered. No major source has yet been identified in MOVPE InN. It has been demonstrated previously that, using the LA-MOVPE technique, an InN film can be deposited between room temperature and 700 \u00b0C [13] . The color of the deposited films changes from yellow to black through dark red when the growth temperature is increased from RT to 700 \u00b0C. The LA-MOVPE sample was found to have a considerably higher carrier concentration than the conventional MOVPE InN. In particular, samples grown at low temperatures contained a high density of oxygen. The present study compares the growth mechanism and electrical characteristics of InN films grown by conventional MOVPE and LA-MOVPE. Based on this comparison, a possible candidate for a donor in MOVPE InN is discussed. 2 Experimental details Using a conventional MOVPE system with a horizontal reactor [14] , single crystalline. InN was grown at 450\u2013650 \u00b0C under 76 or 760 Torr. A carbon susceptor, 18 cm long along the source gas flow direction and 4.5 cm wide, was used [14] . Sapphire (0001) substrates were placed at three different positions on the susceptor at a distance of 3, 9 and 15 cm from the upstream end. Just before the InN growth, the substrate surface was nitrided at 900 \u00b0C for 30 min. Epitaxial InN films with a thickness of 0.2\u20131 \u03bcm were grown with a GaN buffer layer. Triethyle-gallium (TEG), trimethyle-indium (TMI) and NH 3 were used as sources, and N 2 was used as a carrier gas. The NH 3 /TMI molar ratio during growth was changed from 2 \u00d7 10 4 to 5 \u00d7 10 5 . LA-MOVPE growth was performed in a stainless-steel chamber with a provision for resistively heating the substrate [13] . A 193-nm-wavelength ArF excimer laser (COMPex 102, LAMDA PHYSIK) with an output energy of about 50 mJ/pulse and a repetition rate of 20 Hz was used. NH 3 and TMI were used as source materials and N 2 as a carrier gas. Both NH 3 and TMI were introduced into the chamber through a nozzle tube oriented perpendicularly to the substrate surface. The laser beam was aligned parallel to the substrate surface (1\u20132 mm above). The total amount of reactant gas supply (NH 3 and TMI) was about 200 sccm. The NH 3 /TMI molar ratio was (1.5\u201315) \u00d7 10 3 and the reaction chamber pressure was about 1 Torr. Carrier concentration and mobility in InN were obtained by Hall measurements with the van der Pauw method. Photoluminescence (PL) spectra of InN were measured at temperatures from 20 K to room temperature by using a He\u2013Cd laser (442 nm, 300 mW) as an excitation source and a LN-cooled InGaAs pin photodiode (Hamamatsu Photonics, G7754-01) as a detector. Output data from the photodiode were corrected in accordance with the spectral response of the InGaAs photodiode. The grown films were also characterized by AFM and XPS. 3 Results 3.1 Growth and characterization of MOVPE InN In this section, the effects of growth temperature, growth pressure and NH 3 /TMI molar ratio on carrier concentration in conventional MOVPE InN samples are discussed. Fig. 1 shows the growth temperature dependence of MOVPE InN grown under 76 or 760 Torr. The carrier concentration is markedly decreased by increasing growth temperature and also by employing atmospheric pressure. The effect of growth temperature on carrier concentration reduction is found to be strong for both the reduced-pressure and atmospheric-pressure MOVPE samples. Thus, to find the mechanism whereby the growth temperature affects the carrier concentration, it is very important to identify the source of residual donor in MOVPE InN. Fig. 2 shows PL spectra measured at room temperature for atmospheric-pressure MOVPE InN samples grown at different temperatures. With increasing growth temperature up to 620 \u00b0C, the PL intensity is drastically increased and the peak energy shifts to lower energies. For the sample grown at 620 \u00b0C, the PL peak is again reduced with a high peak energy. Emission from the sample grown at around 450 \u00b0C is too weak to be detected. The sample grown at around 600\u2013620 \u00b0C shows the highest and narrowest spectrum with the lowest peak energy (0.685 eV). This and other similar samples show a marked PL intensity change (by more than two orders of magnitude) when the measurement temperature is changed from 20 to 300 K, as shown in the insert in Fig. 2 . The temperature dependence of PL for a sample grown at a low temperature (550 \u00b0C) is very small. The results shown in Figs. 1 and 2 show that the best quality InN is grown at around 600\u2013620 \u00b0C. Although the PL peak energy of 0.685 eV is lower than that reported for some MBE samples [10,11] , it is still higher than the lowest value of 0.64 eV reported for the best MBE InN with a carrier concentration 3.5 \u00d7 10 17 cm \u2212 3 [12] . It should be noted that, as is the case for some MBE samples [10,11] , even the best sample obtained in the present study shows no or a very small PL peak shift as the measurement temperature is decreased from RT to 20 K. This may be due to the considerably high residual donor concentration in the MOVPE samples. It has been reported that the carrier concentration in a reduced-pressure MOVPE InN sample decreased with increasing NH 3 /TMI molar ratio during growth [15] . This was thought to be mainly due to the decrease in the density of nitrogen vacancies. This was because the growth reaction proceeded under an In-rich environment, in which the growth rate of InN was limited by the NH 3 supply, not the TMI supply [16] . In order to determine the growth rate limiting process under atmospheric pressure, the growth rate was measured as a function of TMI supply. Fig. 3 shows the growth rate of InN as a function of TMI supply. Growth rate was measured for samples grown at three different positions along the 18-cm-long susceptor, namely 3, 9 and 15 cm from the upstream end. At any given position on the susceptor, the growth rate increased linearly with increasing TMI supply, suggesting that the growth reaction proceeded under N-rich conditions. Thus, we find that the growth condition of InN is changed from In-rich to N-rich by increasing the growth pressure from 76 to 760 Torr. Fig. 4 shows the carrier concentration in InN grown by atmospheric pressure MOVPE as a function of NH 3 /TMI molar ratio. It is understandable that the effective NH 3 /TMI molar ratio would be different at each substrate position since the TMI concentration decreased along the susceptor due to the consumption by the growth reaction. The growth rate ratio at different positions corresponds to the relative concentration ratio of TMI at these positions. By assuming a constant NH 3 concentration along the susceptor (a reasonable assumption because the NH 3 flow rate is very high (9 slm) and its pyrolytical decomposition rate is very low), the NH 3 /TMI molar ratios at 9 and 15 cm relative to that at 3 cm can be obtained using the growth rate ratio (in Fig. 3 ). Thus, in Fig. 4 , the NH 3 /TMI molar ratios at the substrate positions 9 and 15 cm are corrected. From the results shown in Fig. 4 , one can see that the carrier concentration decreases with increasing NH 3 /TMI molar ratio even when the growth proceeds under N-rich conditions. This shows that the predominant donor in InN must be either an impurity that can substitute an N atom or a N-vacancy related defect. Fig. 5 shows the Hall mobility in InN as a function of NH 3 /TMI molar ratio. One can see that the mobility does not exhibit a strong NH 3 /TMI molar ratio dependence, but does show a decrease at high NH 3 /TMI molar ratios (\u2212 10 6 ). The highest mobility (1100 cm 2 /Vs) is obtained at a relatively low NH 3 /TMI molar ratio. It is noted that the sample with the highest mobility has a relatively high carrier concentration (\u2265 10 19 cm \u2212 3 ), and the sample with the lowest carrier concentration exhibits a relatively low mobility (\u2264 500 cm 2 /Vs). These results indicate that ionized impurity scattering is not predominant in MOVPE InN samples. Since the grain size of InN grown at high NH 3 /TMI molar ratios is much smaller than that of InN grown at low NH 3 /TMI molar ratios (not shown here), grain-boundary scattering seems to predominate in MOVPE InN. 3.2 Growth and characterization of LA-MOVPE InN This section discusses the effects of growth temperature on the properties of LA-MOVPE InN samples. Fig. 6 shows the growth temperature dependence of the carrier concentration, oxygen and nitrogen contents as detected by XPS, and lattice constant c for LA-MOVPE samples. Compared with MOVPE InN, LA-MOVPE samples have a higher carrier concentration (10 20 \u201310 21 cm \u2212 3 ). No PL emission was found in the wavelength range from 0.6 to 2 \u03bcm at room temperature in the case of LA-MOVPE samples. The source materials (TMI and NH 3 ) were from the same suppliers as those for MOVPE and the stainless-steel chamber is better sealed than the MOVPE reactor. As shown in Fig. 1 , the lower growth pressure results in a higher carrier concentration in the MOVPE InN, suggesting that a lower growth pressure can enhance the incorporation of donor sources. Therefore, the higher carrier concentration (10 20 \u201310 21 cm \u2212 3 ) for the LA-MOVPE is reasonable because of the low growth pressure (1 Torr). In the case of LA-MOVPE, the growth rate is limited by TMI supply [13] , indicating that the growth reaction proceeded under N-rich conditions because of the high photolytical decomposition rate of NH 3 . The XPS data in Fig. 6 include oxygen atoms absorbed on the original surface since the surface layer was not removed in this case. This was because sputter etching was found to decompose InN rapidly. When the growth temperature falls below 500 \u00b0C, the oxygen content is markedly increased and nitrogen content is decreased. In good accordance with the increase in oxygen content, the lattice constant c for the LA-MOVPE samples increased with decreasing growth temperature. Despite the lack of direct evidence, one can reasonably conclude that the increases in both the oxygen content and the lattice constant c for samples grown below 500 \u00b0C are due to the formation of InN 1\u2013 x O x alloys. The oxygen level in LA-MOVPE samples grown above 500 \u00b0C is low, namely, on the order of the background level. From the trend of oxygen content increase in Fig. 6 , it is reasonable to consider that oxygen is incorporated into the high-temperature (> 500 \u00b0C) samples although its level is low (at dopant level). 4 Discussion As shown above, the carrier concentration for the MOVPE InN decreased with increasing NH 3 /TMI molar ratio even when the growth proceeded under N-rich conditions. Thus, it is reasonable to conclude that the predominant donor in the MOVPE InN samples was either a substitutional impurity at N sites or a N-vacancy related defect. The study on LA-MOVPE samples, on the other hand, reveals that oxygen can be easily incorporated into InN and form an InN 1\u2013 x O x alloy when a film is grown at a relatively low (< 400 \u00b0C) temperature and pressure (a few Torr). Thus, the high carrier concentration (10 20 \u201310 21 cm \u2212 3 ) in the LA-MOVPE InN grown at relatively high temperature is presumably due to the high concentration of oxygen donor. These results lead us to the conclusion that the most probable donor candidate in MOVPE InN is oxygen. Incorporation of oxygen into InN is enhanced by decreasing growth temperature. This can explain the strong growth temperature dependence of the MOVPE InN ( Fig. 1 ). To find out why the oxygen level incorporated into the film grown at relatively low temperatures (< 500 \u00b0C) is so high, an experiment was conducted to deposit only In metal using a TMI supply (no NH 3 supply) in the LA-MOVPE system. Deposits were obtained at above 350 \u00b0C. Fig. 7 shows the X-ray diffraction profiles of these deposits on sapphire substrates. Surprisingly, the deposits obtained below 400 \u00b0C contained high levels of In 2 O 3 , while those obtained at above 450 \u00b0C contained no detectable indium oxides. This suggests that, owing to their volatility, In\u2013O compounds can be removed from a film growing at high temperature, as in the case of Ga\u2013O compounds [17] . Thus, it is reasonable to conclude that, when deposition is performed below 400 \u00b0C and the growth ambient contains a relatively high oxygen source like O 2 or H 2 O, the resultant InN film contains high levels of oxygen, sometimes even transforming into an InN 1\u2013 x O x alloy. Further studies are necessary to explain the higher oxygen content of films grown under lower pressure. 5 Conclusion The growth of InN was studied by comparing conventional MOVPE and LA-MOVPE using an ArF excimer laser. The carrier concentration in MOVPE InN decreased with increasing NH 3 /TMI molar ratio even when growth proceeded under N-rich conditions. The predominant donor in MOVPE InN seems to be either a substitutional impurity at N sites or a N-vacancy related defect. The LA-MOVPE samples showed that oxygen can be easily incorporated into InN. These results indicate that the most probable donor candidate for MOVPE InN is oxygen. Incorporation of oxygen into InN is enhanced by decreasing growth pressure and temperature. When deposition was carried out below 400 \u00b0C, the resultant InN film contained a high oxygen concentration, sometimes even transforming into an InN 1\u2013 x O x alloy. The higher growth temperature can reduce the oxygen incorporation level. This is presumably due to the volatility of In\u2013O compounds. A carrier concentration of 4.7 \u00d7 10 18 cm \u2212 3 and a mobility of 1100 cm 2 /Vs have been obtained in the case of atmospheric-pressure MOVPE InN. These are the best data reported to date for MOVPE InN. InN film quality can be further improved by reducing the amount of oxygen being incorporated into the growing InN. Acknowledgements This work is partly supported by the New Energy and Industrial Technology Development Organization (NEDO), Japan. References [1] B.E. Foutz S.K. O'Leary M.S. Shur L.F. Eastman J. Appl. Phys. 85 1999 7727 [2] See a recent InN review, Ashraful G. Bhuiyan, A. Hashimoto, A. Yamamoto, J. Appl. Phys. 94 (2003) 2779. [3] V.Y. Davydov A.A. Klochikhin V.V. Emtsev S.V. Ivanov V.V. Vekshin F. Bechstedt J. Furthmuller H. Harima A.V. Mudryi A. Hashimoto A. Yamamoto J. Aderhold J. Graul E. Haller Phys. Status Solidi, B Basic Res. 230 2002 R4 [4] J. Wu W. Walukiewicz K.M. Yu J.W. Ager Jr. E.E. Haller H. Lu W.J. Schaff Y. Saito Y. Nanishi Appl. Phys. Lett. 80 2002 3967 [5] A.G. Bhuiyan K. Sugita K. Kasashima A. Hashimoto A. Yamamoto V.Yu. Davydov Appl. Phys. Lett. 83 2003 4788 [6] A. Yamamoto T. Tanaka K. Koide A. Hashimoto Phys. Status Solidi, A Appl. Res. 194 2002 510 [7] A. Yamamoto K. Sugita H. Takatsuka A. Hashimoto V. Yu. Davydov J. Cryst. Growth 261 2004 275 [8] J. Wu W. Walukiewicz W. Shan K.M. Yu J.W. Ager III E.E. Haller H. Lu W.J. Schaff Phys. Rev., B 66 2002 201403 [9] M. Higashiwaki T. Matsui J. Cryst. Growth 252 2003 128 [10] K. Xu A. Yoshikawa Appl. Phys. Lett. 83 2003 251 [11] Y. Nanishi Y. Saito T. Yamaguchi Jpn. J. Appl. Phys. 42 2003 2549 [12] J. Wu W. Walukiewicz W. Shan K.M. Yu J.W. Ager III S.X. Li E.E. Haller H. Lu W.J. Schaff J. Appl. Phys. 94 2003 4457 [13] A.G. Bhuiyan T. Tanaka K. Kasashima A. Hashimoto A. Yamamoto Jpn. J. Appl. Phys. 42 2003 7284 [14] V. Davydov A. Klochikhin S. Ivanov J. Aderhold A. Yamamoto P. Ruterana M. Albrecht J. Neugebauer Nitride Semiconductors; Handbook on Materials and Devices 2003 Wiley-VCH 241 [15] A. Yamamoto Y. Murakami K. Koide M. Adachi A. Hashimoto Phys. Status Solidi, B Basic Res. 228 2001 5 [16] M. Adachi, Y. Murakami, A. Hashimoto, A. Yamamoto, Proc. InT. Workshop on Nitride Semiconductors, Nagoya, (IPAP Conf. Series 1, 2000) p.339. [17] K. Tone M. Yamada Y. Ide Y. Katayama Jpn. J. Appl. Phys. 31 1992 L721 [18] T.L. Tansley C.P. Foley J. Appl. Phys. 59 1986 3241 [19] V.Y. Davydov A.A. Klochikhin V.V. Emtsev D.A. Kurdyukov S.V. Ivanov V.A. Vekshin F. Bechstedt J. Furthmuller J. Aderhold J. Graul A.V. Mudryi H. Harima A. Hashimoto A. Yamamoto E. Haller Phys. Status Solidi, B Basic Res. 234 2002 787",
        "keywords": [
            "chemical vapor deposition"
        ],
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Hiroshi Miwa",
                "org": "Department of Electrical and Electronics Eng., University of Fukui, Bunkyo 3-9-1, Fukui 910-8507, Japan"
            },
            {
                "name": "Yosuke Shibata",
                "org": "Department of Electrical and Electronics Eng., University of Fukui, Bunkyo 3-9-1, Fukui 910-8507, Japan"
            },
            {
                "name": "Akihiro Hashimoto",
                "org": "Department of Electrical and Electronics Eng., University of Fukui, Bunkyo 3-9-1, Fukui 910-8507, Japan"
            }
        ],
        "venue": "Thin Solid Films",
        "year": 2006
    },
    "6ddMPyok": {
        "id": "6ddMPyok",
        "title": "Photoemission and core absorption studies of indium nitride",
        "abstract": "The vacuum ultra violet and soft X-ray core absorption measurements of InN are carried out using synchrotron radiation. The valence band and core level photoemission measurements are also carried out to investigate the surface conditions of InN thin film. InN thin film is fabricated on nitrided GaAs(11) substrate and is exposed in air. Not only indium and nitrogen elements, but also carbon and oxygen elements are detected by both photoemission and core absorption measurements. Carbon atoms mainly form the amorphous carbon on the film surface. Nitrogen ls core photoemission peaks show the presence of oxynitrides.",
        "keywords": [
            "nitrogen",
            "thin film",
            "amorphous carbon",
            "valence band",
            "synchrotron radiation"
        ],
        "authors": [
            {
                "name": "Kazutoshi Fukui",
                "org": "Department of Electrical and Electronics Engineering, Fukui University, 3-9-1 Bunkyo, Fukui 910, Japan"
            },
            {
                "name": "Masatake Ichikawa",
                "org": "Department of Electrical and Electronics Engineering, Fukui University, 3-9-1 Bunkyo, Fukui 910, Japan"
            },
            {
                "name": "Akio Yamamoto",
                "org": "Department of Electrical and Electronics Engineering, Fukui University, 3-9-1 Bunkyo, Fukui 910, Japan"
            },
            {
                "name": "Masao Kamada",
                "org": "UVSOR, Institute for Molecular Science, Okazaki, Aichi 444, Japan"
            }
        ],
        "venue": "Solid State Electronics",
        "year": 1997
    },
    "xwptXp25": {
        "id": "xwptXp25",
        "title": "Characterization of MOVPE-grown InN layers on \u03b1-Al2O3 and GaAs substrates",
        "abstract": "Heteroepitaxial layers of InN grown on \u03b1-Al 2 O 3 (0 0 0 1), GaAs(1 1 1)B and GaAs(1 0 0) substrates using metalorganic vapor-phase epitaxy (MOVPE) have been characterized comparatively. A single-crystalline InN with wurtzite structure is grown on \u03b1-Al 2 O 3 (0 0 0 1) and GaAs(1 1 1)B substrates, while zincblende InN is grown with a small fraction of wurtzite phase on GaAs(1 0 0) substrate. Surface morphology is the best for InN grown on GaAs(1 1 1)B. Electrical property of InN films on \u03b1-Al 2 O 3 (0 0 0 1) is markedly dependent on NH 3 /TMI molar ratio during the growth. The growth at the atmospheric pressure with a higher NH 3 /TMI molar ratio is found to be effective to achieve excellent electrical properties ( n \u223c5\u00d710 19 cm \u22123 , \u03bc H \u223c300 cm 2 /V s). InN films grown on GaAs(1 1 1)B have a higher carrier density and a lower mobility even when they are grown under the optimized conditions, although they have an excellent surface morphology. PACS 68.55.Ce 73.61.Ey Keywords InN MOVPE \u03b1-Al 2 O 3 GaAs RHEED Carrier density Hall mobility 1 Introduction Indium nitride (InN) is a constituent of GaInN alloys which have attracted much attention for opto-electronic and high-temperature device applications. In contrast to the other constituent GaN, however, there has been only little information about the growth and characterization of InN. This is believed to be due to both that InN has a difficulty to be grown because of the extremely high dissociation pressure and that InN has been thought to be not so attractive by itself for practical application. Recently, however, the technological situation of InN is changing. For example, application of InN to tandem solar cell has been proposed [1] and, also, anomalous electrical behavior at low temperatures has been found for epitaxial InN films [2] . Thus, the technological importance of InN is increasing and research on the growth and characterization of InN is urgently required. Up till now, epitaxial films of InN have been grown by metalorganic vapor-phase epitaxy (MOVPE), molecular beam epitaxy (MBE) and halide vapor-phase epitaxy (HVPE), as well as sputtering. However, data on properties of grown InN are very limited. This paper reports growth and characterization of InN films on \u03b1-Al 2 O 3 and GaAs substrates. The conventional MOVPE method without plasma, which has been employed for the first time to grow single-crystalline InN by Matsuoka et al. [3] , is used in this study. 2 Experimental procedure Using a conventional MOVPE apparatus with a horizontal reactor, InN films with a thickness of 0.2\u20130.5 \u03bcm have been grown. Trimethylindium (TMI) and ammonia (NH 3 ) are used as source materials and N 2 as a carrier gas. Growth temperature and growth pressure are 450\u2013550\u00b0C and 0.1\u20131 atm, respectively. Wafers of \u03b1-Al 2 O 3 (0 0 0 1), GaAs(1 1 1)B and GaAs(1 0 0) are used for substrates. Just before the growth, a substrate surface is nitrided in the flowing NH 3 at 900\u00b0C for 30 min for \u03b1-Al 2 O 3 , and at a temperature in the range of 650\u2013850\u00b0C for 10 min for GaAs. Grown films are characterized by X-ray diffraction (XRD), reflection high-energy electron diffraction (RHEED), atomic force microscopy (AFM) and Hall measurement. 3 Results and discussion 3.1 Crystallographic and morphological characterization Fig. 1 shows RHEED patterns for InN films grown on \u03b1-Al 2 O 3 (0 0 0 1) and GaAs(1 1 1)B substrates. Wurtzite InN is grown on both substrates. The streak pattern for the film on GaAs(1 1 1)B shows the two-dimensional growth of InN on the substrate. In the case of GaAs(1 1 1)B substrates, crystal structure of a GaN layer formed by the nitridation before the InN growth was found to be dependent on nitridation temperature T N ; zincblende structure for T N <700\u00b0C and wurtzite for T N >800\u00b0C. For an InN film grown on a GaAs(1 1 1)B substrate with a zincblende GaN layer, its crystalline structure is changed from zincblende to wurtzite when the thickness exceeds about 0.2 \u03bcm [4] . On a GaAs(1 1 1)B with a wurtzite GaN layer, on the other hand, growth of zincblende InN is not found, that is, a wurtzite InN is grown from the initial stage of the growth. These results suggest that the growth of zincblende InN at the initial growth stage for T N <700\u00b0C is originated by the zincblende GaN layer formed on the substrate surface by the nitridation. Fig. 2 shows AFM images for InN films grown on \u03b1-Al 2 O 3 (0 0 0 1) and GaAs(1 1 1)B substrates. The film grown on \u03b1-Al 2 O 3 (0 0 0 1) substrate has a rough surface because of the columnar fibrous structure [5] . For the film grown on GaAs(1 1 1)B such a structure is not found and the surface is very smooth as expected from the RHEED pattern ( Fig. 1 b). The surface roughness (peak-to-valley) is about 80 nm for the InN layer grown on the \u03b1-Al 2 O 3 (0 0 0 1), while it is about 7 nm for the layer on the GaAs(1 1 1)B. Fig. 3 shows RHEED patterns for InN films grown on GaAs(1 0 0) substrates nitrided at 650 and 850\u00b0C. The patterns were obtained for electron beams parallel to two different \u30080 1 1\u3009 of GaAs(1 0 0), orthogonal [0 1 1] and [0 1 1 \u0304 ]. The patterns with [0 1 1] azimuth show that a single crystalline InN layer with zincblende structure is grown. On the other hand, the patterns with [0 1 1 \u0304 ] azimuth show additional spots originating from wurtzite phase, indicating that the grown layer contains a small fraction of wurtzite InN. Thus, the RHEED pattern is different depending on the electron beam azimuth [0 1 1] or [0 1 1 \u0304 ]. A similar result has been obtained for a GaN layer formed by the nitridation [6] ; the pattern with [0 1 1] azimuth shows additional spots originating from wurtzite GaN, while the pattern with [0 1 1] azimuth does not. This means that the cause for the wurtzite InN growth is the wurtzite GaN involved in the nitrided layer as a buffer layer. Comparison of patterns for 650\u00b0C and 850\u00b0C seems to show that nitridation at a higher temperature results in an increase in the fraction of the wurtzite phase involved. Fig. 4 shows corresponding AFM images of InN films on GaAs(1 0 0). Roughness of a grown film increases with increasing nitridation temperature, which may be correlated with the mixture growth of zincblende and wurtzite domains. 3.2 Electrical characterization Almost all the InN layers grown by a different method usually show a very high carrier density of 10 20 cm \u22123 or more, except for the values of 6\u00d710 16 cm \u22123 [7] and in the order of 10 18 cm \u22123 [3] . This is attributed to high density of nitrogen vacancies in grown films. In this study, carrier density and Hall mobility have been measured for InN films grown under different conditions. Fig. 5 shows relationships between carrier concentration and Hall mobility measured at room temperature for InN films grown on \u03b1-Al 2 O 3 (0 0 0 1) and semi-insulating GaAs(1 1 1)B substrates. One can see that, for films grown on \u03b1-Al 2 O 3 (0 0 0 1), carrier density and Hall mobility are markedly dependent on NH 3 /TMI molar ratio (V/III ratio) in the growth ambient. It is also obvious that the growth at the atmospheric pressure is more effective in reducing the carrier density and increasing the mobility compared to the growth at 0.1 atm. By employing atmospheric pressure growth with an V/III ratio of \u223c10 5 , an InN film with a carrier density of \u223c5\u00d710 19 cm \u22123 and a Hall mobility of \u223c300 cm 2 /V s is reproducibly obtained on \u03b1-Al 2 O 3 (0 0 0 1). Also shown in Fig. 5 are previously reported data for InN. One can see that the results obtained in this study are superior to those reported for films grown by ECR-MBE [8] , ECR-assisted magnetron sputtering [9] , hydride VPE [10] and reactive evaporation with N 2 plasma [11] . The results obtained in this study show that the reduction of nitrogen vacancies in InN is essential to achieve a high quality film. The growth at the atmospheric pressure seems to increase the NH 3 decomposition rate because gases are more effectively heated due to the slower velocity on the susceptor. Also shown in Fig. 5 are the theoretical Hall mobilities calculated for InN by Chin et al. [12] (dashed lines). The number for each line is a compensation ratio. One can see that the compensation ratio is about 0.7 for films grown on \u03b1-Al 2 O 3 (0 0 0 1) at the atmospheric pressure. In contrast with films on \u03b1-Al 2 O 3 (0 0 0 1), those grown on GaAs(1 1 1)B have a high carrier density and a low mobility even when they are grown at the atmospheric pressure with a high V/III ratio. Although the reasons for this is not clear at present, formation of InNAs due to incorporation of As into growing InN may be correlated to this. 4 Conclusions Growth and characterization of InN films on \u03b1-Al 2 O 3 and GaAs substrates have been carried out. The conventional MOVPE method without plasma is employed to grow InN films in this study. A single-crystalline InN with wurtzite structure is grown on \u03b1-Al 2 O 3 (0 0 0 1) and GaAs(1 1 1)B substrates. Surface morphology is found to be the best for a film grown on GaAs(1 1 1)B substrate. RHEED pattern for InN film grown on GaAs(1 0 0) is different depending on the electron beam azimuth, [0 1 1] or [0 1 1 \u0304 ]GaAs; the pattern with [0 1 1] azimuth shows that a single crystalline InN layer with zincblende structure is grown, while another with [0 1 1 \u0304 ] azimuth shows additional spots originating from wurtzite phase. It is found that, for InN films on \u03b1-Al 2 O 3 (0 0 0 1), the growth at the atmospheric pressure with a higher NH 3 /TMI molar ratio is effective to achieve excellent electrical properties. For example, by employing atmospheric pressure growth with an V/III ratio of \u223c10 5 , an InN film with a carrier density of \u223c5\u00d710 19 cm \u22123 and a Hall mobility of \u223c300 cm 2 /V s is reproducibly obtained. On the other hand, InN films grown on GaAs(1 1 1)B have a higher carrier density and a lower mobility even when they are grown under optimized conditions. Acknowledgements This work was supported in part by the Photovoltaic Power Generation Technology Research Association (PVTEC), Japan. References 1 A. Yamamoto M. Tsujino M. Ohkubo A. Hashimoto Solar Energy Mater. Solar Cells 35 1994 53 2 N. Miura H. Ishii A. Yamada M. Konagai Y. Yamauchi A. Yamamoto Jpn. J. Appl. Phys. 36 1997 L256 3 T. Matsuoka, H. Tanaka, T. Sasaki, A. Katsui, in: T. Ikoma, H. Watanabe (Eds.), Proc. 16th Int. Symp. GaAs and Related Compounds, Karuizawa, Japan, 1989, Inst. Phys. Conf. Ser. No. 106, Inst. Phys., Bristol, 1990, p. 141. 4 A. Yamamoto Y. Yamauchi M. Ohkubo A. Hashimoto J. Crystal Growth 174 1997 641 5 C.P. Foley T.L. Tansley Appl. Surf. Sci. 22/23 1985 663 6 A. Yamamoto, T. Shin-ya, Y. Yamauchi, A. Hashimoto, Abstracts Int. Conf. on Silicon Carbide, III-Nitrides and Related Materials-1997, 31 August\u20135 September, Stockholm, Sweden, 1997, p. 249. 7 T.L. Tansley C.P. Foley Electron. Lett. 20 1984 1066 8 C.R. Abernathy S.J. Pearton F. Ren P.W. Wisk J. Vac. Sci. Technol. B 11 1993 179 9 W.A. Bryden S.A. Ecelberger T.J. Kistenmacher Appl. Phys. Lett. 64 1994 2864 10 Y. Sato S. Sato J. Crystal Growth 144 1994 15 11 Y. Sato S. Sato J. Crystal Growth 146 1995 262 12 V.W.L. Chin T.L. Tansley T. Osotchan J. Appl. Phys. 75 1994 7365",
        "keywords": [
            "atmospheric pressure"
        ],
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Tomohiro Shin-ya",
                "org": "Faculty of Engineering, Fukui University, 3-9-1 Bunkyo, Fukui 910, Japan"
            },
            {
                "name": "Toshimitsu Sugiura",
                "org": "Faculty of Engineering, Fukui University, 3-9-1 Bunkyo, Fukui 910, Japan"
            },
            {
                "name": "Akihiro Hashimoto",
                "org": "Faculty of Engineering, Fukui University, 3-9-1 Bunkyo, Fukui 910, Japan"
            }
        ],
        "venue": "Journal of Crystal Growth",
        "year": 1998
    },
    "HdkmAl98": {
        "id": "HdkmAl98",
        "title": "Electron beam irradiation effect for solid C60 epitaxy on graphene",
        "abstract": "We have first observed C 60 nuclei formation induced by electron-beam-irradiation during van der Waals epitaxy of solid C 60 layers on a graphene sheets. The experimental results strongly indicate that the positional control of the C 60 nuclei on the graphene sheet is expected to fabricate new nano-structure by the C 60 clusters on the graphene sheet and it will lead us to new principle devices such as the solid Q-bit clusters of N@C 60.",
        "keywords": [
            "Epitaxial graphene",
            "van der Waals epitaxy",
            "Step-flow growth",
            "Solid C60 layer"
        ],
        "authors": [
            {
                "name": "Akihiro Hashimoto",
                "org": ""
            },
            {
                "name": "Hiromitsu Terasaki",
                "org": "Graduate School of Electrical & Electronics Engineering, University of Fukui, Bunkyo 3-9-1, Fukui 910-8507, Japan"
            },
            {
                "name": "Akio Yamamoto",
                "org": "Graduate School of Electrical & Electronics Engineering, University of Fukui, Bunkyo 3-9-1, Fukui 910-8507, Japan"
            },
            {
                "name": "Satoru Tanaka",
                "org": "Departments of Applied Quantum Physics and Nuclear Engineering, Kyusyu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan"
            }
        ],
        "venue": "Diamond & Related Materials",
        "year": 2009
    },
    "jN5J61zj": {
        "id": "jN5J61zj",
        "title": "Raman scattering of indium-rich AlxIn1\u2212xN: Unexpected two-mode behavior of A1(LO)",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Ting-Ting Kang",
                "org": ""
            },
            {
                "name": "Akihiro Hashimoto",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "Physical Review B",
        "year": 2009
    },
    "MlDZ6Lt3": {
        "id": "MlDZ6Lt3",
        "title": "Anomalous Electrochemical Behavior of N-Type GaN Films on \u03b1-Al2O3 Substrates",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Yasuyuki Tsuji",
                "org": ""
            },
            {
                "name": "Toshimitsu Sugiura",
                "org": ""
            },
            {
                "name": "Akihiro Hashimoto",
                "org": ""
            }
        ],
        "venue": "Japanese Journal of Applied Physics",
        "year": 1999
    },
    "FOJxrXcG": {
        "id": "FOJxrXcG",
        "title": "Suppression of hexagonal GaN mixing by As4 molecular beam in cubic GaN growth on GaAs (001) substrates",
        "abstract": "A mechanism of hexagonal GaN crystal-phase mixing in cubic GaN growth under As 4 molecular beam irradiation on GaAs (0 0 1) substrates has been investigated. It is found that the As 4 beam irradiation during growth of the GaN is effective for the suppression of the hexagonal GaN mixing on the {1 1 1} A planes, although it is not so effective for the {1 1 1} B planes. The results strongly indicate that the high-quality cubic GaN layers will be obtained in the MBE growth by the As 4 beam irradiation combined with the formation techniques of the atomically flat surfaces such as the high-temperature atomic hydrogen treatment. PACS 81.60.Cp Keywords c-GaN growth h-GaN mixing As 4 molecular beam 1 Introduction Cubic GaN (c-GaN) grown on GaAs (0 0 1) substrate, although a metastable crystal phase, is expected to have several advantages for device application due to its higher crystallographic symmetry [1] . However, the crystalline quality of the reported c-GaN layers was not good enough for the device applications [2] . A major problem for the c-GaN growth is the mixing one of hexagonal GaN (h-GaN) crystal phase into the c-GaN layers during the growth. The mixing is mainly caused by the slight energy difference between the c-GaN and the h-GaN that are thermodynamically metastable and stable phases, respectively. Therefore, it is expected that the low-temperature and non-equilibrium crystal growth technique like molecular beam epitaxy (MBE) is the most promising one to obtain the c-GaN single crystal layers. Recently, in fact, several improvements of the crystal quality of the c-GaN in the MBE growth by the As surfactant during the growth or the high-temperature atomic hydrogen treatment of the GaAs substrates before the growth have been reported [1,2] . However, the roles of the As atoms and/or the surface flatness in the initial low-temperature buffer layer (LTBL) formation, their annealing and the following growth processes have not been so well understood. In this paper, a suppression effect of the h-GaN mixing by As 4 molecular beam in the c-GaN growth on the GaAs (0 0 1) substrates is systematically investigated. 2 Experimental procedures GaN growth was carried out by the gas source molecular beam epitaxy (GSMBE) system using the metal Ga and the dimethyl-hydrazine (DMHy) as a nitrogen source. The 1000 \u00c5-thick GaN layers were grown at 700\u00b0C after the LTBL (200 \u00c5) formation at 450\u00b0C by the two step growth technique on the (0 0 1) GaAs substrates. The initial (2\u00d74) GaAs (0 0 1) clean surfaces were obtained by thermally cleaning of the GaAs (0 0 1) substrates under the As 4 pressure or by the additionally 5000 \u00c5-thick GaAs buffer layer growing on the thermally cleaned (2\u00d74) surfaces to study on the effect of the GaAs surface flatness. A suppression effect of the h-GaN mixing was investigated by the As 4 molecular beam irradiations during the low-temperature GaN buffer layer formation process and/or the GaN growth process after the initial nucleation by the thermal annealing of the buffer layer under the DMHy irradiation. Typical beam-equivalent pressures of the DMHy and the As 4 beams were 1\u00d710 \u22125 and 1\u00d710 \u22126 Torr, respectively. Characterizations of the growth process were carried out by using the in-situ reflection high-energy electron diffraction (RHEED) and the X-ray reciprocal space maps (RSMs) [3] . 3 Results and discussion Fig. 1 shows the typical RHEED patterns with the \u30081 1\u0304 0\u3009 incident azimuth from the GaN grown layers (a) with and (b) without the As 4 beam irradiation during the LTBL formation, their annealing and the following growth processes. Only the zincblende RHEED pattern can be observed in the case of the GaN layer grown with the As 4 beam irradiation, although a mixed RHEED pattern with the weak zincblende and the tilted hexagonal ones is observed in the case of the GaN layer grown without the As 4 beam irradiation, as shown in Fig. 1 . However, the RHEED patterns with the \u30081 1 0\u3009 incident azimuth showed the mixed ones in both cases. Fig. 2 shows the typical RHEED patterns with the \u30081 1\u0304 0\u3009 incident azimuth from (a) the GaN initial layer (2 0 0 \u00c5) just after the annealing process of LTBL with the As 4 beam irradiation and from (b) the following GaN grown layer (1000 \u00c5) without the As 4 beam irradiation. As shown in Fig. 2 a, only the zincblende RHEED pattern can be observed at the initial growth stage by the mixing suppression effect of As 4 beam, however then, a hexagonal pattern emerges during the following GaN growth without the As 4 beam irradiation as shown in Fig. 2 b. The in situ RHEED results strongly indicate that the As 4 beam irradiation during the growth is effective for the suppression of the h-GaN growth mixing perpendicular to the {1 1 1} A planes. In order to precisely investigate the mixing of the h-GaN in the c-GaN epitaxial layers, the RSMs around both the c-GaN (0 0 2) and the h-GaN (1 0 1\u0304 1) peaks for the X-ray beams incident along both the \u30081 1\u0304 0\u3009 and the \u30081 1 0\u3009 azimuths of the GaAs substrates were measured [2] . Fig. 3 shows the typical RSMs for the GaN grown layers (a) with and (b) without the As 4 beam irradiation during the whole growth processes, when the incident X-ray azimuth was the \u30081 1\u0304 0\u3009 direction. The \u03b8 \u20132 \u03b8 measurements were performed from 35\u00b0 to 45\u00b0, and \u03c8 , that is defined as the substrate angle tilted toward the \u30081 1 0\u3009 directions from the normal position in the \u03b8 \u20132 \u03b8 measurements, was changed \u00b110\u00b0. Only one peak from the c-GaN (0 0 2) was observed as shown in Fig. 3 a; the peaks from the h-GaN (1 0 1\u0304 1) which indicate the h-GaN phase grown on the {1 1 1} A planes were not observed for the As 4 beam irradiation sample. On the other hand, in contrast with Fig. 3 a, three peaks from the c-GaN (0 0 2) and the h-GaN (1 0 1\u0304 1) were observed for the sample grown without the As 4 beam irradiation as shown in Fig. 3 b. The results shown in Fig. 3 indicate that the As 4 beam irradiation is effective for the suppression of the h-GaN phase mixing perpendicular to the {1 1 1} A planes. However, the results of the RSMs measurements along the \u30081 1 0\u3009 incident X-ray azimuth indicate that the mixing of h-GaN into the c-GaN layers is not always suppressed for both cases in Fig. 3 . Therefore, the As 4 beam irradiation in the GaN growth process is not so much effective to suppress the mixing of the h-GaN phase perpendicular to the {1 1 1} B planes. The results also indicate that the origin of the stacking faults that exist predominantly on the {1 1 1} B planes may be different from the case in the {1 1 1} A planes. It is worth to note that the only zincblende RHEED pattern emerged with the \u30081 1 0\u3009 incident azimuth during the nitridation of the GaAs (0 0 1) surface with the As 4 beam irradiation, in contrast with the case of the GaN growth in this work. This implies that it is easier to form the c-GaN structures from the GaAs and/or the GaN {1 1 1}B planes than the {1 1 1} A ones. According to Nagano et al., the surface flatness obtained by the high-temperature atomic-H treatment is the most important factor to suppress the mixing of the h-GaN phases on the {1 1 1}B planes [4] . Although we tried to grow a GaN layer with the As 4 beam irradiation on a rather flat GaAs (0 0 1) surface obtained by the 5000 \u00c5-thick GaAs buffer layer, the suppression effect for the {1 1 1}B planes could not be observed. Therefore, the origin of the stacking faults that exist predominantly on the {1 1 1} B planes may be strongly related with the atomically flat surfaces that have the high-density monolayer steps and kinks at the surface terrace edges as reported by Nagano et al., and it is expected that the high-quality c-GaN layers can be grown by the As 4 beam irradiation during the GaN growth on the atomically flat GaAs (0 0 1) surface obtained by the high-temperature atomic-H treatment. 4 Conclusions In conclusion, we have systematically investigated a suppression effect of the h-GaN mixing by the As 4 molecular beam in the c-GaN growth on the GaAs (0 0 1) substrates. It is found that the As 4 beam irradiation during the growth of GaN is effective for the suppression of the h-GaN mixing on the {1 1 1} A planes and the different origin of the h-GaN mixing on the {1 1 1}B planes such as the initial surface flatness may exist. Therefore, it is expected to grow the high-quality c-GaN layers by the As 4 beam irradiation combined with the formation techniques of the atomically flat surfaces such as the high-temperature atomic-H treatment. References [1] H. Okumura H. Hamaguchi K. Ohta G. Feuillet K. Balakrishnan Y. Ishida S. Chichibu H. Nakanishi T. Nagatomo S. Yoshida Mater. Sci. Forum 264\u2013268 1998 1167 [2] A. Yoshikawa Z. Qin H. Nagano Y. Sugure A. Jia M. Kobayashi Y. Kato K. Takahashi Mater. Sci. Forum 264\u2013268 1998 1221 [3] H. Tsuchiya K. Sunada T. Suemasu F. Hasegawa J. Crystal Growth 189/190 1998 395 [4] H. Nagano Z. Qin A. Jia Y. Kato M. Kobayashi A. Yoshikawa K. Takahashi J. Crystal Growth 189/190 1998 265",
        "keywords": [],
        "authors": [
            {
                "name": "Akihiro Hashimoto",
                "org": ""
            },
            {
                "name": "Takanori Motizuki",
                "org": "Department of Electrical and Electronics Engineering, Faculty of Engineering, Fukui University, Bunkyo 3-9-1, Fukui 910-0017, Japan"
            },
            {
                "name": "Hideki Wada",
                "org": "Department of Electrical and Electronics Engineering, Faculty of Engineering, Fukui University, Bunkyo 3-9-1, Fukui 910-0017, Japan"
            },
            {
                "name": "Atsushi Masuda",
                "org": "School of Materials Science, Japan Advanced Institute of Science and Technology, 1-1 Asahidai, Tatsunokuchi, Ishikawa 923-1292, Japan"
            },
            {
                "name": "Akio Yamamoto",
                "org": "Department of Electrical and Electronics Engineering, Faculty of Engineering, Fukui University, Bunkyo 3-9-1, Fukui 910-0017, Japan"
            }
        ],
        "venue": "Journal of Crystal Growth",
        "year": 1999
    },
    "RKpxhKos": {
        "id": "RKpxhKos",
        "title": "Phase separation of thick (\u223c1 \u00b5m) InxGa1\u2212xN (x \u223c 0.3) grown on AlN/Si(111): Simultaneous emergence of metallic In\u2013Ga and GaN-rich InGaN",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "akio yamamoto",
                "org": "university of fukui"
            },
            {
                "name": "md tanvir hasan",
                "org": "university of fukui"
            },
            {
                "name": "akihiro mihara",
                "org": "university of fukui"
            },
            {
                "name": "norihiko narita",
                "org": ""
            },
            {
                "name": "naoteru shigekawa",
                "org": "osaka city university"
            },
            {
                "name": "masaki kuzuhara",
                "org": "university of fukui"
            }
        ],
        "venue": "Applied Physics Express",
        "year": 2014
    },
    "MQlOWQmN": {
        "id": "MQlOWQmN",
        "title": "Origins of n-type residual carriers in RF-MOMBE grown InN layers",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Kosuke Iwao",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Akihiro Hashimoto",
                "org": ""
            }
        ],
        "venue": "Physica Status Solidi (c)",
        "year": 2007
    },
    "VbrQBsmS": {
        "id": "VbrQBsmS",
        "title": "Enhanced two-dimensional growth of MOVPE InN films on sapphire (0001) substrates",
        "abstract": "MOVPE growth of InN on sapphire substrates is compared using two different designs of horizontal reactor. The major difference between the two designs is a variation in the reactant-gas flow-spacing between the substrate and the ceiling of the quartz chamber: 33 mm for the Type A reactor and 14 mm for Type B. Compared with the Type A reactor, the Type B reactor brings about InN films with a larger grain size. This is especially true when InN is grown at 600\u00b0C using the Type B reactor, in which case the two-dimensional (2D) growth of InN is found to be extremely enhanced. An investigation of the NH 3 /TMIn molar ratio dependence of the surface morphology of grown InN films using the two reactors suggests that the enhanced 2D growth is attributed to the decrease in the effective NH 3 /TMIn ratio in the growth atmosphere. Even using the Type A reactor, a film with enhanced 2D growth can be obtained when the NH 3 /TMIn ratio is considerably low (\u223c1.8\u00d710 4 ). The enhanced 2D growth results in a smaller XRC-FWHM (full-width at half maximum of the X-ray rocking curve) (\u2a7d1500 arcsec), than that for a 3D-grown film (\u223c5000 arcsec). Keywords A1. Crystal morphology A3. Metalorganic vapor phase epitaxy B1. Nitrides B2. Semiconducting indium compounds 1 Introduction The performance of GaN-based devices depends critically on the quality of epitaxial films. In obtaining high-quality GaN films with the MOVPE method, reactor design has been found to be one of the critical factors. Nakamura et al. [1] reported that high-quality GaN films were grown using the two-flow MOCVD reactor, where the inactive subflow gas was used to change the direction of the reactant gas in contact with the substrate surface. Nishida et al. [2] have improved GaN film quality by employing an MOCVD horizontal reactor with separate carrier-gas and reactant-gas entry, in which the carrier gas in the upper stream suppresses the reactant gas to form a laminar flow pattern above the susceptor. Yang et al. [3] studied the effects of reactant-gas flow-spacing between the substrate and the ceiling of the quartz chamber on the morphology of grown GaN films, and discussed their results with the boundary-layer model. In spite of many works on GaN growth, the essential roles of reactor design on growth behavior have not yet been fully understood. Compared with GaN, little information about the growth of InN is available. Typically, InN films grown on sapphire substrates by MOVPE have a columnar fibrous structure as a result of three-dimensional (3D) growth [4] . In this paper, MOVPE growth of InN is studied using two different designs of horizontal reactor. It is found that two-dimensional (2D) growth of MOVPE InN is extremely enhanced by employing a reactor with a smaller, as opposed to a larger, flow-spacing between the substrate and the ceiling of the quartz chamber. Such enhancement of 2D growth is attributed to the decrease of effective V/III ratio in the growth atmosphere, since, with a conventional reactor, enhanced 2D growth of InN can be obtained by decreasing the NH 3 /TMIn molar ratio. 2 Experimental procedure Epitaxial films of InN are grown on \u03b1-Al 2 O 3 (0 0 0 1) substrates at a reduced pressure (0.1 atm) using an MOVPE system with a horizontal reactor. Fig. 1 shows cross-sectional views of the horizontal reactors used in the study. Both reactors are composed of a quartz tube (diameter 54 mm), but the reactors differ in their reactant-gas flow-spacing between the susceptor and the ceiling of the quartz chamber. Compared with the Type A reactor, Type B has a smaller flow-spacing: 14 mm for Type B, whereas 33 mm for Type A. As reactant sources, trimethyleindium (TMIn) is introduced with N 2 carrier gas through the lower entrance of either reactor, and ammonia (NH 3 ) through the upper one. The TMIn supply is varied from 1.4 to 14 \u03bcmol/min, while the NH 3 flow rate is kept constant (6 SLM). This corresponds to the change in the NH 3 /TMIn molar ratio from 1.8\u00d710 5 to 1.8\u00d710 4 . The growth of InN is carried out at 500\u2013600\u00b0C for 2 h. The grown films range in thickness from 100 to 400 nm. Prior to InN growth, the substrate surface is heated at 950\u00b0C for 10 min in H 2 and then nitrided in the flowing NH 3 at 900\u00b0C for 30 min. Grown films are characterized with a scanning electron microscope (SEM), atomic force microscopy (AFM), and X-ray diffraction rocking curve (XRC). 3 Results and discussion Fig. 2 shows the growth rate of the InN at different temperatures as a function of the TMIn supply for the Type A reactor. In Fig. 2 , two important facts should be noted. One is that the growth rate increases with increasing growth temperature. The other is the saturation of the growth rate against the increase in the TMIn supply. These facts can be well explained by taking into account that growth rate is not limited by the TMIn supply but by the NH 3 decomposition rate [5] . This is because the thermal decomposition rate of NH 3 at 500\u2013600\u00b0C is considerably low [6] . No marked differences are found in growth rates between Type A and Type B reactors. Fig. 3 shows the AFM images for InN films grown at 500\u00b0C or 600\u00b0C using each of the reactors. One can see that films grown at 500\u00b0C have a characteristic feature of small grains ( Figs. 3(a) and (c) ). Such a feature is due to the columnar fibrous structure of InN [4] as a result of 3D growth. It is also found that the Type B reactor brings about a larger grain size of grown InN than does the Type A. When growth takes place at 600\u00b0C, differences in the morphology of grown films between the two reactors are emphasized. As can be seen in Fig. 3(d) , the film grown at 600\u00b0C using the Type B reactor has very large grains with a smooth surface, showing that 2D growth is extremely enhanced. It should be noted that, at 600\u00b0C, 2D growth is enhanced in spite of the increase in growth rate. As described below, the reason for the enhanced 2D growth using the Type B reactor is clarified through the investigation of NH 3 /TMIn molar ratio dependence of the surface morphology of films for each reactor. Fig. 4 shows the surface morphology of InN films grown using the Type B reactor with different NH 3 /TMIn molar ratios. As can be seen in the figure, 2D growth is depressed even with the Type B reactor ( Fig. 4(a) ) when the NH 3 /TMIn ratio is increased to 1.8\u00d710 5 . Very large grains with a smooth surface are obtained with an NH 3 /TMIn ratio of less than 4.5\u00d710 4 . For the film grown with an NH 3 /TMIn ratio of 3\u00d710 4 , grain size is still very large, although many pits are formed on the enlarged grain surface ( Fig. 4(c) ). Even with the Type A reactor, similar changes in surface morphology are observed when the NH 3 /TMIn ratio is varied. The results are shown in Fig. 5 . When the growth takes place with a high NH 3 /TMIn ratio (7\u00d710 4 ), InN grows with relatively small grains, and the sapphire substrate is not entirely covered with InN, as shown in Fig. 5(a) . Such an exposure of the substrate after growth is not observed for films grown at 500\u00b0C with the same reactant source supplies. This means that some etching process may occur at 600\u00b0C. As for the case with films grown by the Type B reactor, 2D growth is also enhanced with decreasing NH 3 /TMIn ratio. When the NH 3 /TMIn ratio is reduced to 1.8\u00d710 4 , a film with large grains and many pits on the surface is obtained, as seen in Fig. 5(c) . This result is very similar to that for the film grown using the Type B reactor with an NH 3 /TMIn ratio of 3.0\u00d710 4 ( Fig. 4(c) ). Thus, even with the Type A reactor, enhanced 2D growth of InN can be attained by reducing the NH 3 /TMIn ratio. Okumura et al. [7] reported that the Ga-rich condition brought about a 2D growth mode in the MBE growth of GaN. Therefore, it is reasonable to consider in this case that the 2D growth of InN under the low NH 3 /TMIn ratio condition is due to the realization of an In-rich growth condition. According to the boundary-layer model [8] , an increase in gas velocity will lead to a decrease in the concentration of NH 3 and TMIn. However, it is unclear whether or not gas velocity changes the NH 3 /TMIn ratio. It can be concluded that an NH 3 flow with a higher velocity is heated less effectively and then decomposes less effectively. Therefore, the mechanism for the less-effective NH 3 /TMIn ratio in the Type B reactor is a reduced NH 3 decomposition rate, which occurs because the smaller spacing results in a higher gas velocity. One may expect that a low NH 3 /TMIn ratio condition with a high TMIn supply causes an increase in growth rate and, therefore, that a high growth rate can depress 2D growth of InN, since a higher growth rate allows less time for adsorbed atoms to diffuse on the surface. As shown in Fig. 2 , however, growth rate is not increased with increasing TMIn supply in this case, because it is limited by the NH 3 decomposition rate. Fig. 6 shows the full-width at half-maximum X-ray diffraction rocking curve (XRC-FWHM) of InN films grown with either the Type A or B reactor as a function of NH 3 /TMIn ratio during growth. For the Type B reactor, XRC-FWHM decreases with decreasing NH 3 /TMIn molar ratio, and reaches 1500 arcsec at an NH 3 /TMIn ratio of 1.8\u00d710 4 . This result shows that the 2D growth is essential for improving the crystalline quality of grown InN. It should be noted that such a reduction of XRC-FWHM is also found with films grown with the Type A reactor. In this case, XRC-FWHM is reduced when the NH 3 /TMIn ratio is less than 3\u00d710 4 , while the reduction of FWHM for the Type B reactor starts when the NH 3 /TMIn ratio is approximately 7\u00d710 4 . From these results, it follows that the effective NH 3 /TMIn ratio in the Type B reactor can be roughly estimated to be about half of that in the Type A reactor. 4 Conclusion In summary, MOVPE growth of InN on sapphire substrates was studied using two types of horizontal reactors that we prepared. One type had reactant-gas flow-spacing of 33 mm, while the other had spacing of 14 mm. The reactor with the smaller (14 mm) spacing brought about InN films with larger grain size. When InN was grown at 600\u00b0C using this reactor, the 2D growth of InN was extremely enhanced. The primary cause of the enhanced 2D growth was concluded to be a decrease in effective NH 3 /TMIn ratio in the growth atmosphere. This decrease was caused by a reduced NH 3 decomposition rate, which in turn was a result of the higher gas-flow velocity in the narrower reactor. Even using the reactor with the larger spacing (33 mm), enhanced 2D growth was obtained when the NH 3 /TMIn ratio was reduced to 1.8\u00d710 4 . A low NH 3 /TMIn ratio condition with a high TMIn supply can be expected to cause an increase in growth rate, and a high growth rate can depress the 2D growth of InN. However, growth rate in this case was not increased with an increasing TMIn supply. The reason for this was that the growth rate was limited by the NH 3 supply, because of the extremely low thermal decomposition rate of NH 3 at 500\u2013600\u00b0C. As a result of the enhanced 2D growth, the FWHM of the X-ray rocking curve was reduced to less than 1500 arcsec from 5000 arcsec for the reactor with the larger spacing. This suggests that 2D growth is essential for improving the crystalline quality of grown InN. References [1] S. Nakamura Y. Harada M. Seno Appl. Phys. Lett. 58 1991 2021 [2] K. Nishida S. Haneda K. Hara H. Munekata H. Kukimoto J. Crystal Growth 170 1997 312 [3] C.-C. Yang G.-C. Chi C.-K. Huang M.-C. Wu J. Crystal Growth 200 1999 32 [4] A. Yamamoto Y. Yamauchi M. Ohkubo A. Hashimoto J. Crystal Growth 174 1997 641 [5] M. Adachi, Y. Murakami, A. Hashimoto, A. Yamamoto, International Workshop on Nitride Semiconductors, IWN 2000, Nagoya, September 24\u201327, 2000, PMD-06. [6] M. Mesrine N. Grandjean J. Massies Appl. Phys. Lett. 72 1998 350 [7] H. Okumura K. Balakrishnan H. Hamaguchi T. Koizumi S. Chichibu H. Nakanishi T. Nagatomo S. Yoshida J. Crystal Growth 189/190 1998 364 [8] G.B. Stringfellow, Organometallic Vapor-Phase Epitaxy: Theory and Practice, Academic Press, Boston, 1989, p. 228.",
        "keywords": [
            "grain size",
            "full width at half maximum"
        ],
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Masato Adachi",
                "org": "Department of Electrical and Electronics Engineering, Faculty of Engineering, Fukui University, 3-9-1 Bunkyo, Fukui 910-8507, Japan"
            },
            {
                "name": "Akihiro Hashimoto",
                "org": "Department of Electrical and Electronics Engineering, Faculty of Engineering, Fukui University, 3-9-1 Bunkyo, Fukui 910-8507, Japan"
            }
        ],
        "venue": "Journal of Crystal Growth",
        "year": 2001
    },
    "KSTom1Q3": {
        "id": "KSTom1Q3",
        "title": "Initial growth stage of GaN on Si substrate by alternating source supply using dimethyl-hydrazine",
        "abstract": "Alternating source supply mehtod of Ga an N sources is proposed to control the initial nitridation stages for the direct growth of GaN on Si. The initial growth stages under the alternating source supply are characterized by the X-ray photoelectron spectroscopy and the atomic force microscope. A suppression effect for the nitridation of Si surface by an excess Ga supply is investigated. The systematic analysis of the spectra shows that the Ga atoms play an important role in both the removal of Si native oxides and the suppression of the nitridation during the initial growth stages. The atomic force microscopic images show that the surface morphologies depend on the substrate temperature of the initial growth stages. The surface morphology of the sample grown at 500\u00b0C is smoother than the one grown at 600\u00b0C. This implies that there is a possibility to realize the growth conditions for the pseudo Stranski-Krastanov growth mode without Si nitridation at the initial stages in a low temperature region in the alternating source supply method for the direct growth of III\u2013V nitrides on Si.",
        "keywords": [
            "dimethyl-hydrazine",
            "initial growth stage",
            "81.15.hi",
            "alternating source supply",
            "gan on si",
            "atomic force microscope",
            "x ray photoelectron spectroscopy"
        ],
        "authors": [
            {
                "name": "Akihiro Hashimoto",
                "org": ""
            },
            {
                "name": "Yoshitaka Aiba",
                "org": "Department of Electrical and Electronics Engineering, Fukui University, Bunkyo 3-9-1, Fukui 910, Japan"
            },
            {
                "name": "Takanori Motizuki",
                "org": "Department of Electrical and Electronics Engineering, Fukui University, Bunkyo 3-9-1, Fukui 910, Japan"
            },
            {
                "name": "Mitugu Ohkubo",
                "org": "Department of Electrical and Electronics Engineering, Fukui University, Bunkyo 3-9-1, Fukui 910, Japan"
            },
            {
                "name": "Akio Yamamoto",
                "org": "Department of Electrical and Electronics Engineering, Fukui University, Bunkyo 3-9-1, Fukui 910, Japan"
            }
        ],
        "venue": "Journal of Crystal Growth",
        "year": 1997
    },
    "ZfOPoSIN": {
        "id": "ZfOPoSIN",
        "title": "Elucidation of factors obstructing quality improvement of MOVPE-grown InN",
        "abstract": "",
        "keywords": [
            "nitrogen",
            "thermal decomposition",
            "quality improvement"
        ],
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Ken-ichi Sugita",
                "org": "Graduate School of Engineering, University of Fukui, 3-9-1 Bunkyo, Fukui 910-8507, Japan"
            },
            {
                "name": "Akihiro Hashimoto",
                "org": "Graduate School of Engineering, University of Fukui, 3-9-1 Bunkyo, Fukui 910-8507, Japan"
            }
        ],
        "venue": "Journal of Crystal Growth",
        "year": 2009
    },
    "sljpAtP5": {
        "id": "sljpAtP5",
        "title": "Suppression of hexagonal GaN mixing by As 4 molecular beam in cubic GaN growth on GaAs (001) substrates",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "akihiro hashimoto",
                "org": ""
            },
            {
                "name": "takanori motizuki",
                "org": ""
            },
            {
                "name": "hideki wada",
                "org": ""
            },
            {
                "name": "atsushi masuda",
                "org": ""
            },
            {
                "name": "akio yamamoto",
                "org": ""
            }
        ],
        "venue": "Journal of Crystal Growth",
        "year": 1999
    },
    "ifj2xu2w": {
        "id": "ifj2xu2w",
        "title": "Growth and Characterization of Epitaxial InN Films on Sapphire Substrate using an ArF Excimer Laser-Assisted Metalorganic Vapor-Phase Epitaxy (LA-MOVPE)",
        "abstract": "",
        "keywords": [
            "band gap",
            "inn",
            "room temperature",
            "movpe"
        ],
        "authors": [
            {
                "name": "Ashraful Ghani Bhuiyan",
                "org": ""
            },
            {
                "name": "Tatsuya Tanaka",
                "org": ""
            },
            {
                "name": "Ken Kasashima",
                "org": ""
            },
            {
                "name": "Akihiro Hashimoto",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "Japanese Journal of Applied Physics",
        "year": 2003
    },
    "DT85KXt6": {
        "id": "DT85KXt6",
        "title": "Nitrogen K-edge Absorption of AlInN",
        "abstract": "The soft X-ray absorption (SXA) around nitrogen K-edge (N-K) h ave been measured to investigate the electronic structure of the wurzite III - V nitrides, especially the structure of the unoccupied states. The N-K absorption spectra of III - V nitrides near the N K-edge in principle represent the partial density of the final states with p symmetry according to the selection rule. Since the core levels are strictly localized in space, the N-K absorption spectrum gives us the site-specific information. The N-K absorption spectrum also gives us the information about the final states symmetry pxy and pz, because the incidence soft X-ray light is linearly polarized. In this report, we represent the first results of N-K SXA spectra of wurtzite Al1-xInxN (x= 0, 0.53, 0.78, 1). The experiments were carried out at BL8B1. Resolution power under the experimental conditions was about 0.5 eV at 400 eV. The soft X-ray absorption measurement was performed by using the total photoelectron yield (TY) method. Thin films were made by the MOCVD method at RIKEN on SiC substrates (x = 0 ), at Fukui University on GaAs(111) surface (x = 1) and at Meijo University (x = 0.53, 0.78) on \u03b1-Al2O3 substrates. All films were cleaned with organic solvents just before the installation in the vacuum chamber. No specific surface cleaning of the samples was performed in the vacuum chamber. The TY measurements were carried out at room temperature in the range of 10 -9 Torr. Sample holder was able to rotate in the vacuum chamber for the angular dependent measurement. The incidence angle \u03b8 is defined as the angle between the incident light and the normal axis of the sample surface, i.e., c-axis. The incidence angle dependent SXA measurements were performed under the p-polarization configuration which means E parallel to c-axis at \u03b8 ~ 90 o , where E was the electric field of the incident light. Figure 1 shows the N-K absorption spectra of Al1-xInxN (x= 0, 0.53, 0.78, 1). The energy scale is relative to the threshold energy corresponds to the conduction band minimum. The intensity is normalized at the maximum peak in each spectrum. The spectra features of AlN (x = 0) and InN (x = 1) are good agreement with the previous works (1-3). The spectrum feature shows the structure-less spectra of x = 0.78 and, in particular, x = 0.53. Figure 2 shows the N-K absorption of Al0.78In0.22N as",
        "keywords": [],
        "authors": [
            {
                "name": "Kazutoshi FUKUI",
                "org": ""
            },
            {
                "name": "Akio YAMAMOTO",
                "org": "Faculty of Engineering|Fukui University"
            },
            {
                "name": "Satoru TANAKA",
                "org": "Research Institute for Electronic Science|Hokkaido University"
            },
            {
                "name": "Yoshinobu AOYAGI",
                "org": "Institute of Physical and Chemical Research"
            },
            {
                "name": "Shigeo YAMAGUCHI",
                "org": "High-Tech Research Center|Meijo University"
            },
            {
                "name": "Hiroshi AMANO",
                "org": "High-Tech Research Center|Meijo University"
            },
            {
                "name": "Isamu AKASAKI",
                "org": "High-Tech Research Center|Meijo University"
            }
        ],
        "venue": "",
        "year": 0
    },
    "dfh3nrDF": {
        "id": "dfh3nrDF",
        "title": "van der Waals epitaxy of solid C60 on graphene sheet",
        "abstract": "We have investigated on the van der Waals epitaxy of a solid C 60 layer on a graphene sheet and have first successfully achieved it. It is expected that the hetero-structures of the solid C 60 layer and the graphene sheet opens new opportunities in the carbon nano-electronics.",
        "keywords": [
            "Graphene",
            "Solid C 60 layer",
            "van der Waals epitaxy"
        ],
        "authors": [
            {
                "name": "Akihiro Hashimoto",
                "org": ""
            },
            {
                "name": "Kohsuke Iwao",
                "org": "Department of Electrical and Electronics Engineering, Fukui University, Japan"
            },
            {
                "name": "Satoru Tanaka",
                "org": "Department of Applied Quantum Physics and Nuclear Engineering, Kyusyu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan"
            },
            {
                "name": "Akio Yamamoto",
                "org": "Department of Electrical and Electronics Engineering, Fukui University, Japan"
            }
        ],
        "venue": "Diamond & Related Materials",
        "year": 2008
    },
    "MUuCQlMV": {
        "id": "MUuCQlMV",
        "title": "Nitridation of GaAs(111) by dimethyl-hydrazine (DMHy) with As4 molecular beam",
        "abstract": "Wide temperature range nitridation of GaAs(1 1 1) substrates by DMHy with As 4 molecular beam have been investigated to convert GaAs to GaN. The nitridation rate strongly depends on the pressures of the DMHy and the As 4 beams and the substrate temperature. The nitridation even at higher temperature range for the GaAs substrates is possible by using simultaneous supply of the DMHy and the As 4 beams. The RHEED from the nitrided layers of the GaAs(1 1 1) B substrates shows a strong zincblende pattern mixed with a weak wurtzite one in the investigated temperature range, in contrast to the case of the nitridation for the GaAs(1 1 1) A substrates in which the RHEED shows a wurtzite one only. The results indicate that the nitridation process can be controlled by the simultaneous supply of the DMHy and the As 4 beams. PACS 81.60.Cp Keywords Nitridation GaAs(1 1 1) Dimethyl-hydrazine (DMHy) As 4 beam 1 Introduction III\u2013V nitride wide gap semiconductors such as GaN are of great interest in the application of optoelectronic devices such as light-emitting diodes and laser diodes [1, 2] . For thermal growth, nitridation, performed by exposing the substrate to reactive nitrogen species such as dimethyl-hydrazine (DMHy), has been shown to be a key step in the growth of GaN films on substrates such as Al 2 O 3 and GaAs [3\u20138] . However, the mechanism behind the nitridation lies in the initial growth stage to form the epitaxial layers with good crystal quality in the molecular beam epitaxial (MBE) growth is still not very well understood. Especially, for the III\u2013V nitride growth on the GaAs substrates, the relationship between the initial nitridation and the initial buffer layer may not be clear yet. Therefore, it is important to investigate the nitridation process at the initial growth stage from the view point of the following growth of III\u2013V nitrides on the GaAs substrates. Moreover, the nitridation technique itself has an attractive potential to convert from the conventional III\u2013V compounds such as GaAs and AlGaAs to their derived III\u2013V nitride ones. If it is possible to obtain a suitable III\u2013V nitride alloy of device quality by nitridation, it will open up the possibilities of the new extensive applications in the fabrication processes of the future integrated devices such as quantum optoelectronic integrated circuits (Q-OEIC). However, studies of the kinetics of nitridation and the quality of nitrided films of GaAs have not been systematically reported so much, in contrast to the ones of the crystal growth [9] . In this paper, we report on the wide temperature range study of the nitridation of GaAs(1 1 1) substrates by the DMHy with the As 4 molecular beam to convert GaAs to the derived GaN. 2 Experimental procedures The nitridation of GaAs(1 1 1) A and B substrates was performed by using the gas source molecular beam epitaxial (GSMBE) system. The exposure time to the DMHy and the temperature range for the nitridation were about 90 min and 550\u2013800\u00b0C, respectively. The pressure range of DMHy was 2\u00d710 \u22127 \u22126\u00d710 \u22124 Torr and the As 4 beam pressure was held constant at 1\u00d710 \u22124 Torr. The DMHy was supplied by a nozzle located near the substrate holder. Characterization of the nitrided films was carried out by using reflection high-energy electron diffraction (RHEED), \u03b8 \u20132 \u03b8 X-ray diffraction ( \u03b8 \u20132 \u03b8 XRD), scanning electron microscopy (SEM) and the atomic force microscopy (AFM). 3 Results and discussion Fig. 1 shows the \u03b8 \u20132 \u03b8 XRD relative peak intensity of the zincblende (ZB) mixed with the wurtzite (WZ) GaN to GaAs(1 1 1) versus the DMHy pressure for the nitridation without As 4 beam for the GaAs(1 1 1) B substrates. As shown in Fig. 1 , the relative peak intensity rapidly increases to around 10 \u22125 Torr and the temperature dependence of it at the constant pressure of DMHy can be observed. The SEM observations showed that the unexpected decreases of the intensity at 650\u00b0C were due to the surface degradation caused by the rapid As desorption, as shown in Fig. 2 . The results indicate that there is a need to suppress the rapid As desorption during nitridation in the higher temperature range. Fig. 3 shows the temperature dependence of the \u03b8 \u20132 \u03b8 XRD relative peak intensity of nitrided GaN layers from the GaAs(1 1 1) A and B substrates under the DMHy pressure of 6\u00d710 \u22124 Torr with the As 4 beam in the temperature range of 550\u2013800\u00b0C. In Fig. 3 , some data under the same DMHy pressure without As 4 beam as already shown in Fig. 1 are also plotted. As shown in the case of (1 1 1) B substrates, the relative intensity of GaN layers nitrided under the As 4 pressure at 650\u00b0C clearly increases compared to the one without As 4 beam. The surface morphology was also improved and was rather smooth than in the case without As 4 beam as shown in Fig. 2 . However, the relative peak intensity remarkably decreases around 700\u00b0C without morphology degradation, and then it gradually increases up to 800\u00b0C. A similar temperature dependence except for the value of the relative peak intensity was also observed in the case of the nitridation under the As 4 pressure for the (1 1 1) A substrates as shown in Fig. 3 . In both cases A and B, the thickness of GaN layer nitrided at 650\u00b0C was about 2400 \u00c5, but, in the temperature range higher than 700\u00b0C, it was less than about 1200 \u00c5. Such temperature dependence for both the XRD relative peak intensity and the nitrided film thickness are the unexpected results from the ordinary counter diffusion picture of As and N, and it implies that some additional processes such as the desorption of the Ga atoms during the nitridation play an important role at the higher temperature region. In general, the peak separation of the WZ and the ZB GaN structures is difficult for the [1 1 1] crystal direction in the \u03b8 \u20132 \u03b8 XRD measurements in Fig. 1 , and, in fact, the two kind of structures, WZ and the ZB GaN contribute to the peak intensity in the (1 1 1) B case, in contrast to the (1 1 1) A one, from the results of the RHEED observation discussed in the following paragraph. Therefore, the \u03c9 -mode scan in the XRD measurements is needed to estimate each contribution to the peak intensity, exactly. However, in the present cases, the variation of the XRD peak intensity in Figs. 1 and 3 shows the strong correlation to the temperature dependence of the nitrided film thickness. Therefore, it is not mainly related to the crystal quality of the nitrided films but to the nitrided film thickness. On the other hand, almost one order of magnitude difference in the value of the relative peak intensity between the A and B cases as shown in Fig. 3 are certainly and srtongly related to the crystal quality of the nitrided films as suggested from the following RHEED observations, as well as the full-width at half-maxima of the XRD peaks. Therefore, the \u03c9 -mode scan XRD measurement should be performed to characterize the nitrided film quality and the detailed results of which will be reported in near future. Fig. 4 shows the RHEED patterns of the nitrided GaAs(1 1 1) B as a function of the nitridation time under the As 4 pressure at 650\u00b0C. As shown in Fig. 4 b, the ZB GaN pattern appears immediately after the supply of the DMHy to the clean GaAs(1 1 1) B surface, and then, the spots intensity of the ZB GaN pattern gradually increases along with the nitridation time, in contrast to the decrease of the one in the GaAs pattern ( Fig. 4 c). The RHEED pattern after nitridation for 90 min consists of the strong and the weak patterns from ZB GaN and WZ GaN, respectively, as shown in Fig. 4 d. The intensities of the spots in both RHEED patterns for ZB and WZ GaN saturate after nitridation for longer than 60 min. The RHEED patterns of the higher-temperature nitrided samples under the As 4 pressure and the lower-temperature nitrided ones without the As 4 beam also always showed the strong ZB GaN pattern mixed with the weak WZ GaN one similar to the cases shown in Fig. 4 . However, the change in the RHEED pattern as a function of the nitridation time for the (1 1 1) A is quite different from the case of (1 1 1) B. As shown in Fig. 5 b, the ZB GaN pattern appears immediately after the supply of the DMHy to the clean (1 1 1) A surface for nearly 10 min similar to the case of B. However, then the ZB GaN pattern disappears completely at once and, simultaneously, the WZ GaN pattern appears in place of it as shown in Fig. 5 c. Only the WZ GaN pattern with the saturated spot intensity has been observed after nitridation for longer than 60 min ( Fig. 5 d). The thickness of the GaN layers after nitridation for 90 min in both cases is typically about 2400 \u00c5. Although the mechanisms of formation of the two different crystal structures by the nitridation is not clear under the present investigation, the above results suggest that the different surface atomic structures between the (1 1 1) A and the (1 1 1) B planes strongly influence the kinetics of the nitridation process. Fig. 6 shows the typical AFM images after the nitridation of the GaAs(1 1 1) (a) A and (b) B planes. The morphology is quite different from each other as shown in Fig. 6 . Some stacked islands, which are surrounded by the facet-like planes, arrange along the particular direction and the surface morphology is far from being atomically flat for the nitrided (1 1 1) B surface. On the other hand, the morphology for the nitrided (1 1 1) A surface is smoother than the nitrided (1 1 1) B surface, although many bunched step-like structures can be observed. The origin of such a difference in the surface morphology is not yet clear, but it may be related to the nitridation mechanism and the crystal structures formed by the nitridation as shown in Figs. 4 and 5 . It is easily anticipated that the epitaxial layers will be strongly influenced by such surface morphology after the nitridation at the initial stage of the crystal growth. 4 Conclusions In conclusion, we have investigated the wide temperature range nitridation of GaAs(1 1 1) A and B substrates by the simultaneous supply of the DMHy and the As 4 molecular beams to convert GaAs to GaN. The nitridation rate depends on the pressures of the DMHy and the As 4 beams and the substrate temperature, and the nitridation at higher temperature is possible by using a simultaneous supply of the DMHy and the As 4 beams. The results also imply that the kinetics of nitridation in the higher-temperature range over 700\u00b0C under the As 4 pressure may be rather different from the ones in the lower-temperature range. Moreover, the RHEED and the AFM observations also revealed the different futures of the nitridation process for the (1 1 1) B and A planes. Acknowledgements This work was supported by Grant-in-Aid for Science Research by The Japanese Ministry of Education, Science and Culture. References 1 I. Akasaki H. Amano S. Sato H. Sakai T. Tanaka M. Koike Jpn. J. Appl. Phys. 34 1995 L1517 2 S. Nakamura M. Senoh T. Mukai Appl. Phys. Lett. 62 1993 2390 3 A. Yamamoto M. Tsujino M. Ohkubo A. Hashimoto J. Crystal Growth 137 1994 415 4 H. Okumura S. Misawa S. Yoshida Appl. Phys. Lett. 59 1991 1058 5 S. Fujieda Y. Matsumoto Jpn. J. Appl. Phys. 30 1991 L1665 6 S. Yoshida H. Okumura S. Misawa E. Sakuma Surf. Sci. 267 1992 50 7 N. Kuwano Y. Nagatomo K. Kobayashi K. Oki S. Miyoshi H. Yaguchi K. Onabe Y. Shiraki Jpn. J. Appl. Phys. 33 1994 18 8 K.W. Vogt P.A. Kohl J. Appl. Phys. 74 1993 6448 9 M.E. Jones J.R. Shealy J.R. Engstrom Appl. Phys. Lett. 67 1995 542",
        "keywords": [],
        "authors": [
            {
                "name": "Akihiro Hashimoto",
                "org": ""
            },
            {
                "name": "Takanori Motizuki",
                "org": "Department of Electrical and Electronics Engineering, Faculty of Engineering, Fukui University, 3-9-1 Bunkyo, Fukui-shi, Fukui 910, Japan"
            },
            {
                "name": "Yohichi Kurumi",
                "org": "Department of Electrical and Electronics Engineering, Faculty of Engineering, Fukui University, 3-9-1 Bunkyo, Fukui-shi, Fukui 910, Japan"
            },
            {
                "name": "Akio Yamamoto",
                "org": "Department of Electrical and Electronics Engineering, Faculty of Engineering, Fukui University, 3-9-1 Bunkyo, Fukui-shi, Fukui 910, Japan"
            }
        ],
        "venue": "Journal of Crystal Growth",
        "year": 1998
    },
    "x8rZ1YdC": {
        "id": "x8rZ1YdC",
        "title": "Growth temperature dependent critical thickness for phase separation in thick (~1\u03bcm) In x Ga 1\u2212x N ( x =0.2\u20130.4)",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "akio yamamoto",
                "org": ""
            },
            {
                "name": "md tanvir hasan",
                "org": ""
            },
            {
                "name": "k kodama",
                "org": ""
            },
            {
                "name": "naoteru shigekawa",
                "org": ""
            },
            {
                "name": "masaaki kuzuhara",
                "org": ""
            }
        ],
        "venue": "Journal of Crystal Growth",
        "year": 2015
    },
    "ZSvn1vwG": {
        "id": "ZSvn1vwG",
        "title": "Two dimensional electron gas in InN-based heterostructures: Effects of spontaneous and piezoelectric polarization",
        "abstract": "This paper predicts and describes the formation of two dimensional electron gas (2DEG) in InN-based heterostructures, as a promising candidate for future high performance high electron mobility transistor (HEMT). The effects of spontaneous and piezoelectric polarization on carrier confinement and localization of 2DEGs have been studied. These include the theoretical analysis and calculation of spontaneous and piezoelectric polarization, and polarization induced sheet charge bound at the interfaces of InN/InGa(Al)N/InN heterostructures as a function of lattice mismatch induced strain. Significant effects of polarity are found on carrier confinement and localization of 2DEGs. A high sheet carrier concentration and strong electron confinement at specific interfaces of the InN-based heterostructures are predicted as a consequence of piezoelectric and spontaneous polarization effects. The calculated sheet carrier concentration reaches as high as 2.12 \u00d7 10 14 and 7.08 \u00d7 10 13 cm \u22122 for AlN and GaN barriers, respectively. These sheet carriers generated in InN-based heterostructures are higher than the reported values for the conventional GaN-based AlGaN/GaN HEMTs. The accumulation of electrons can be confirmed for a barrier thickness of above 4 nm. Keywords InN Polarization Two dimensional electron gas (2DEG) Sheet carrier concentration 1 Introduction The III-nitride semiconductors have attracted intense interest for both electronic and optoelectronic device applications [1\u20133] . The large polarization charge densities present at III-nitride heterojunction interfaces profoundly influence electric field and mobile carrier distributions, necessitating their incorporation into device design and analysis and providing opportunities for device engineering [4,5] . It has been shown that piezoelectric effects can exert a substantial influence on the concentration and distribution of free carriers in strained III-nitride heterostructures with the wurtzite crystal structure grown in the (0 0 0 1) orientation [6] . In addition to the high piezoelectric polarization, the spontaneous polarization (polarization at zero strain) is also very large in wurtzite III-nitrides, increasing from GaN over InN to AlN [7] , resulting in a further increase of polarization induced effects in nitride-based HEMTs. Polarization induced electric fields lead to a significant increase of the sheet carrier concentration and narrower confinement of the 2DEG [8,9] . A large conduction band discontinuity results in better electron confinement and allows for a higher sheet charge density in the well at the heterointerface. Therefore, details understanding and proper inclusion of these effects in the design and analysis of high performance nitride-based electronic devices are of immense importance. The latest progress in improving the InN film quality indicates that the InN film itself almost meets the requirements for application to practical devices [10] . It is expected to be a highly promising material for the fabrication of high performance HEMT. InN as a HEMT channel requires a larger band gap barrier to induce and confine electrons. The probable choices of barriers are GaN or AlN or their alloys with InN, InGaN or InAlN. The significant lattice mismatch between InN and GaN or AlN can result in a large piezoelectric charge, which is very advantageous for HEMT applications. In order to design and fabricate the InN-based HEMTs details understanding and proper inclusion of the effects of spontaneous and piezoelectric polarizations are very much essential. However, there is very little theoretical works on the InN-based heterostructures [11] . Most of the works carried out on conventional GaN-based AlGaN/GaN heterostructures. In this work, we have theoretically studied the effects of spontaneous and piezoelectric polarization on carrier confinement and localization of 2DEGs in InN-based heterostructures. The effects of polarity and barrier thickness are also studied. These include the theoretical analysis and calculation of polarization, polarization induced sheet charge and sheet carrier concentration at interfaces in InN/InGa(Al)N/InN heterostructures. The inherent electron accumulation at InN surface due to the effects of surface charge and dislocation densities is not considered. 2 Polarity and polarization The polarity, whether the III-face (In, Ga, Al) or the N-face forms the surface, of the epitaxial layer in III-nitride based semiconductors is found to be very important. The polarity of III-nitrides is a subject that has seen much research recently [12] . The fact that the material has wurtzite crystal symmetry means that there exists a polarity in the growth direction, yielding either III-face (0 0 0 1) or N-face ( 0 0 0 1 \u00af ) material. This polarity issue has several important consequences, some of which are the differing materials properties of the different polarities as well as how the different polarities can be achieved from a growth point of view. The polarity also determines the orientation of the spontaneous and piezoelectric polarization inside the material, which has drastic effects on device design. Depending on the polarity of material grown, the 2DEG will be formed at different interfaces. If the polarity flips over from III-face to N-face material, the piezoelectric as well as the spontaneous polarization changes its sign [6] . Fig. 1 shows the direction of the spontaneous polarization ( P SP ) and piezoelectric polarization ( P PZ ) for In-face and N-face strained InGa(Al)N/InN and InN/InGa(Al)N heterostructures. The orientation of the spontaneous and piezoelectric polarization is defined assuming that the positive direction goes from the metal (cation) to the nearest neighbor nitrogen atom (anion) along the c -axis. The spontaneous polarization of the III-nitrides is found to be negative while the piezoelectric polarization is negative for tensile strain and positive for compressive strain [7] . As a consequence, the alignment of the piezoelectric and spontaneous polarization is parallel in the case of tensile strain, and antiparallel in the case of compressive strain as shown in Fig. 1 . Therefore, for the heterostructures where the InGa(Al)N layers are grown on relaxed InN layers the piezoelectric and spontaneous polarization point in the same direction. While for the heterostructures where the InN layers are grown on relaxed InGa(Al)N layers the piezoelectric and spontaneous polarization point in the opposite direction. Since the value of the total polarization is the sum of the piezoelectric and spontaneous polarization, the spontaneous polarization can play an important role to increase or decrease the total polarization and to confine the carriers. Therefore, understanding of the spontaneous polarization is also very important. The spontaneous polarization of the In-face InGaN and InAlN ternary nitride alloys is given by the following equations [3] . P InGaN SP ( x ) = - 0.042 x - 0.034 ( 1 - x ) + 0.037 x ( 1 - x ) C / m 2 P AlInN SP ( x ) = - 0.090 x - 0.042 ( 1 - x ) + 0.070 x ( 1 - x ) C / m 2 . The calculated spontaneous polarization of In-face InGaN and AlInN alloys with the variation of In composition is shown in Fig. 2 . The variation of spontaneous polarization is remarkable in InAlN, with the In composition, compared to InGaN. For a material to exhibit an anisotropic property such as piezoelectricity, its crystal structure must have no centre of symmetry [13] that amounts to a piezoelectric polarization. When stress is applied on piezoelectric materials the induced piezoelectric polarization P i PZ for wurtzitic structure can be expressed as P i PZ = \u2211 k , j = 1 6 d ij T k , where T k are the stresses and i = 1 , 2 , 3 . P i PZ = \u2211 k , j = 1 6 d ij C kj \u03b5 j , where d ij are the piezoelectric moduli. Again, P i PZ = \u2211 j e ik \u03b5 j , where the piezoelectric constants, e ik = \u2211 j d ij C kj . The nonvanishing component of the piezoelectric polarization caused by biaxial strain is (1) P 3 PZ = 2 \u03b5 1 e 31 - e 33 C 13 C 33 , where e ik = 0 for all other components. As a consequence of Eq. (1) and the linear interpolation of the elastic and piezoelectric constants, the piezoelectric polarization is nonlinear in terms of the alloy composition. The nonlinear dependence of the piezoelectric polarization on the alloy composition can be approximated with the following quadratic equations. P InGaN / InN PZ = [ - 0.113 ( 1 - x ) - 0.0276 x ( 1 - x ) ] C / m 2 , P InAlN / InN PZ = [ - 0.28 x - 0.104 x ( 1 - x ) ] C / m 2 . The theoretically calculated P PZ of the InGa(Al)N alloys on relaxed InN layer and InN on relaxed InGa(Al)N with the variation of In composition of InGa(Al)N layer for both In- and N-face are shown in Fig. 3 . The P PZ decreases with the increase of In composition of InGa(Al)N layer due to reduction in lattice mismatch. It is to be mentioned here that the values of piezoelectric polarization is negative for tensile and positive for compressive strain in In-face layers while opposite values are obtained for N-face layers. The P PZ is found to be varied from 10.4 \u00d7 10 \u221202 to 1.4 \u00d7 10 \u221202 C/m 2 and 24.3 \u00d7 10 \u221202 to 1.9 \u00d7 10 \u221202 C/m 2 , respectively, for In-face InGaN and InAlN on relaxed InN with the variation of In composition from x = 0.1 to 0.9 as shown in Fig. 3 a. The P PZ is found to be varied from 14.4 \u00d7 10 \u221202 to 1.61 \u00d7 10 \u221202 C/m 2 and 17.7 \u00d7 10 \u221202 to 1.98 \u00d7 10 \u221202 C/m 2 , respectively, for N-face InN on relaxed InGaN and InAlN, with the variation of In composition from x = 0.1 to 0.9 as shown in Fig. 3 b. 3 Sheet charge density Associated with a gradient of polarization in space is a polarization induced charge density given by \u03c1 P = \u2212\u2207 P . The sheet charge density is induced due to the abrupt change of the total polarization at the surface of a relaxed or strained III-nitride layer, as well as at the interfaces of an III-nitride based heterostructure. At present, the exact mechanism for the surface charge accumulation of InN is still under investigation. In recent studies, the inherent electron accumulation has been found at InN surface due to downward band bending and this behavior may be similar to that of InAs [14\u201316] . In the present works, the sheet charge density has been calculated at the interface of InN-based heterostructures in which the effects of the inherent electron accumulation are not considered. At an abrupt interface of a top/bottom layer (InGa(Al)N/InN or InN/InGa(Al)N heterostructures), the polarization can decrease or increase within a bilayer, causing a fixed polarization sheet charge density defined [17] by \u03c3 P SP + P PZ = P bottom - P top = P bottom SP + P bottom PZ - P top SP + P top PZ = P bottom PZ - P top PZ + P bottom SP - P top SP = \u03c3 P PZ + \u03c3 P SP . The calculated sheet charge densities ( \u03c3 ) at the interfaces of both In- and N-face InN/InGa(Al)N/InN heterostructures with the variation of the In composition of InGaN and InAlN barriers are shown in Fig. 4 . The calculated values of polarization induced sheet charge densities are found to be negative at the lower interface (InGa(Al)N/InN) and positive at the upper interface (InN/InGa(Al)N) for the N-face heterostructures as shown in Fig. 4 a. Opposite results are obtained for In-face heterostructures as shown in Fig. 4 b. If the polarization induced sheet charge density is positive (+ \u03c3 ), free electrons will tend to compensate the polarization induced charge. These electrons will form a 2DEG. A negative sheet charge density (\u2212 \u03c3 ) will cause an accumulation of holes at the interface. Therefore, in the case of In-face heterostructure the 2DEG is expected to be closed to the lower interface (InGa(Al)N/InN), while in N-face heterostructure it is expected to occur close to the upper interface (InN/InGa(Al)N) for positive sheet charge as shown in the inset of Fig. 4 . The sheet charge density decreases with the increase of In composition of the InGa(Al)N barrier, because of the reduction in strain, and therefore, the piezoelectric polarization is decreasing. For the N-face heterostructure, the calculated values of sheet charge densities at the upper interface are found to be varied from 14.46 \u00d7 10 \u221206 to 1.02 \u00d7 10 \u221206 C/cm 2 and 13.04 \u00d7 10 \u221206 to 1.13 \u00d7 10 \u221206 C/cm 2 for InN/InGaN and InN/InAlN, respectively, with the variation of In composition from x = 0.1 to 0.9. For the In-face heterostructure, the calculated values of sheet charge densities at lower interface are found to be varied from 10.37 \u00d7 10 \u221206 to 1.97 \u00d7 10 \u221206 C/cm 2 and 28.95 \u00d7 10 \u221206 to 2.71 \u00d7 10 \u221206 C/cm 2 for InGaN/InN and InAlN/InN, respectively, with the variation of In composition from x = 0.1 to 0.9. The calculated values of sheet charge densities at the interfaces of InGa(Al)N/InN heterostructures, where 2DEG is predicted to be confirmed, are in good agreement with the theoretical and experimental reported values for the conventional GaN-based AlGaN/GaN HEMTs [3,6,17] . These calculated sheet charges at the interface are about ten times higher than in comparable heterostructures of other III\u2013V heterostructures [18] , thus high polarization induced sheet carrier concentrations may be expected. The above results offer the possibility to control the electron confinement. 4 Carrier confinement and 2DEG To successfully model and further optimize the electronic devices, a precise prediction and control of the sheet carrier concentrations of the polarization induced 2DEGs is required. With a theoretical understanding of the polarization induced charge, we now can predict the sheet carrier concentration ( n S ) of 2DEG and their dependence on alloy composition. For In-face InGa(Al)N/InN or InN/InGa(Al)N/InN structures, the sheet electron concentration n S ( x ) can be calculated using the total bound sheet charge \u03c3 ( x ) and the following equations [8,17] : n S ( x ) = \u03c3 ( x ) e - \u03b5 o \u03b5 ( x ) d InGa ( Al ) N e 2 e \u03a6 b ( x ) + E F ( x ) - \u0394 E C ( x ) , or n S ( x ) = 1 + \u03b5 ( x ) \u03b5 o d InN d InGa ( Al ) N - 1 \u03c3 ( x ) e - \u03b5 o \u03b5 ( x ) d InGa Al N e 2 e \u03a6 b eff ( x ) + E F ( x ) - \u0394 E C ( x ) , respectively. \u03b5 ( x ) is the relative dielectric constant of In x Ga 1\u2212 x N, d InGa(Al)N and d InN are the thicknesses of the barrier and the cap layer, e\u03a6 b ( x ) is the Schottky barriers of the gate contact on top of barrier, E F ( x ) is the Fermi level with respect to the InN conduction-band-edge energy, which is considered as 95 meV [19] , and \u0394 E C ( x ) is the conduction band offset at the InGa(Al)N/InN interface. It is assumed that polarization in ternary nitride alloys interpolates linearly between the limiting values determined by the binary compounds using Vegard\u2019s law. There is significant change in lattice constants, dielectric constants, spontaneous and piezoelectric polarization for varying compositions of the ternary materials which is shown in the following equations [3] . Dielectric constants: \u03b5 InGaN ( x ) = 4.33 x + 10.28 , \u03b5 AlInN ( x ) = - 4.30 x + 14.61 . Schottky barrier for Ni contact: e \u03a6 InGaN ( x ) = ( - 0.36 x + 0.84 ) eV, e \u03a6 AlInN ( x ) = ( 1.66 x + 0.48 ) eV. Bandgaps: E InGaN g ( x ) = [ 0.70 x + 3.42 ( 1 - x ) - 2.5 x ( 1 - x ) ] eV, E AlInN g ( x ) = [ 6.13 x + 0.70 ( 1 - x ) - 5.4 x ( 1 - x ) ] eV. Band offsets: \u0394 E InGa ( Al ) N C ( x ) = 0.63 E InGa ( Al ) N g ( x ) - E InGa ( Al ) N g ( 0 ) . The calculated sheet carrier concentrations at the lower interface of In-face InN/InGa(Al)N/InN heterostructures as a function of In composition of the InGa(Al)N barriers are shown in Fig. 5 . The thickness of the barrier layer is considered 54 nm. The sheet carrier concentrations are found to be decreased from 7.08 \u00d7 10 13 to 8.94 \u00d7 10 12 cm \u22122 for InGaN and 2.12 \u00d7 10 14 to 1.6 \u00d7 10 13 cm \u22122 for InAlN with the increase of the In composition from x = 0 to 0.9. The sheet carrier concentration generated by the InAlN barrier is higher than that of InGaN barrier. The calculated values of sheet carrier concentration are in good agreement with the theoretical and experimental values reported for the InN-based and conventional GaN-based heterostructures [6,11,14] . The sheet carriers generated in InN-based heterostructures are found to be higher than the reported values for the conventional GaN-based AlGaN/GaN HEMTs [17] . The values are well above those observed in other III\u2013V material systems [6] . The calculated results show that 2DEG is generated by spontaneous and piezoelectric polarization effects with high sheet carrier concentration which is suitable for HEMT. The effects of barrier thickness on sheet carrier concentration have also been studied. Fig. 6 shows the variation of the sheet carrier concentrations for InGaN/InN heterostructure with the widths of the InGaN barrier layer for different In composition. The sheet carrier concentrations increase with increase of the InGaN barrier thickness in InGaN/InN heterostructures. Similar study is also carried out for InAlN barriers. For a thickness of the InGaN and InAlN barriers above 4 nm accumulation of the electrons can be confirmed for InGa(Al)N/InN-based heterostrucures. There is no effect of composition on the thickness of the barrier, which is also shown in Fig. 6 . 5 Conclusion We have investigated the effects of piezoelectric and spontaneous polarization on carrier confinement and localization of 2DEG in InN-based heterostructures. These include the theoretical analysis and calculation of spontaneous and piezoelectric polarizations and polarization induced sheet charge and sheet carrier as a result of the lattice mismatch induced strain. It is found that polarity of the grown structure plays substantial influence on charge density and electron confinement. The polarization induced sheet charge density is found to be varied from 10.37 \u00d7 10 \u221206 to 1.97 \u00d7 10 \u221206 C/cm 2 for InGaN/InN and 28.95 \u00d7 10 \u221206 to 2.71 \u00d7 10 \u221206 C/cm 2 for InAlN/InN with the variation of In composition from x = 0.1 to 0.9. The calculated sheet carrier concentration reaches as high as 2.12 \u00d7 10 14 and 7.08 \u00d7 10 13 cm \u22122 for AlN and GaN barriers, respectively. And the sheet carrier concentration is found to be varied from 7.08 \u00d7 10 13 to 9.073 \u00d7 10 12 cm \u22122 for InGaN and 2.12 \u00d7 10 14 to 1.6 \u00d7 10 13 cm \u22122 for InAlN barrier with the increase of the In composition from x = 0 to 0.9. These sheet carriers generated in InN-based heterostructures are higher than the reported values for the conventional GaN-based AlGaN/GaN HEMTs. The sheet carrier generated by InAlN barrier is higher than that of InGaN barrier. By increasing the thickness of the InGaN barrier from 4 to 54 nm, the sheet carrier concentration increases from n S = 3.1 \u00d7 10 12 to 7.08 \u00d7 10 13 cm \u22122 . The accumulation of the electrons is confirmed for a barrier thickness of above 4 nm. The possibility to control the 2DEG is also discussed. References [1] C.Y. Lai T.M. Hsu W.-H. Chang K.U. 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Chu Two dimensional electron gases induced by spontaneous and piezoelectric polarization in undoped and doped AlGaN/GaN heterostructures J Appl Phys 87 2000 334 344 [18] W.Q. Chen S.K. Hark Strain-induced effects in (1 1 1)-oriented InAsP/InP, InGaAs/InP, and InGaAs/InAlAs quantum wells on InP substrates J Appl Phys 77 1995 5747 5750 [19] Davydov V. Yu A.A. Klochikhin V.V. Emtsev A. Hashimoto A. Yamamoto E.E. Haller Band Gap of Hexagonal InN and InGaN Alloys Phys Status Solidi (b) 234 2002 787 795",
        "keywords": [
            "two dimensional electron gas",
            "polarization",
            "inn",
            "high electron mobility transistor"
        ],
        "authors": [
            {
                "name": "Md. Tanvir Hasan",
                "org": ""
            },
            {
                "name": "Ashraful G. Bhuiyan",
                "org": "Department of Electrical and Electronic Engineering, Khulna University of Engineering and Technology (KUET), Khulna 920300, Bangladesh"
            },
            {
                "name": "Akio Yamamoto",
                "org": "Department of Electrical and Electronics Engineering, University of Fukui, Bunkyo 3-9-1, Fukui 910-507, Japan"
            }
        ],
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        "year": 2008
    },
    "XbmWRNeT": {
        "id": "XbmWRNeT",
        "title": "Terahertz characterization of semiconductor alloy AlInN: negative imaginary conductivity and its meaning: reply to comment",
        "abstract": "",
        "keywords": [
            "terahertz"
        ],
        "authors": [
            {
                "name": "Ting-Ting Kang",
                "org": ""
            },
            {
                "name": "Masatomo Yamamoto",
                "org": ""
            },
            {
                "name": "Mikiyasu Tanaka",
                "org": ""
            },
            {
                "name": "Akihiro Hashimoto",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Ryota Suto",
                "org": ""
            },
            {
                "name": "Akifumi Noda",
                "org": ""
            },
            {
                "name": "D. W. Liu",
                "org": ""
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                "org": ""
            }
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    },
    "rh1liEJJ": {
        "id": "rh1liEJJ",
        "title": "Metalorganic chemical vapor deposition growth of InN for InN/Si tandem solar cell",
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        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
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                "name": "Mitsunori Tsujino",
                "org": "Department of Electrical and Electronics Engineering, Faculty of Engineering, Fukui University, 3-9-1 Bunkyo, Fukui, Fukui, 910 Japan"
            },
            {
                "name": "Mitsugu Ohkubo",
                "org": "Department of Electrical and Electronics Engineering, Faculty of Engineering, Fukui University, 3-9-1 Bunkyo, Fukui, Fukui, 910 Japan"
            },
            {
                "name": "Akihiro Hashimoto",
                "org": "Department of Electrical and Electronics Engineering, Faculty of Engineering, Fukui University, 3-9-1 Bunkyo, Fukui, Fukui, 910 Japan"
            }
        ],
        "venue": "Solar Energy Materials and Solar Cells",
        "year": 1994
    },
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        "id": "qjEiUeiA",
        "title": "New laser ablation phenomenon of the porous Si films by focused N2 pulse laser irradiation",
        "abstract": "",
        "keywords": [
            "thin film",
            "quantum dot"
        ],
        "authors": [
            {
                "name": "akihiro hashimoto",
                "org": ""
            },
            {
                "name": "kakuya iwata",
                "org": ""
            },
            {
                "name": "mitugu ohkubo",
                "org": ""
            },
            {
                "name": "akio yamamoto",
                "org": ""
            }
        ],
        "venue": "Journal of Applied Physics",
        "year": 1994
    },
    "W13lxPXn": {
        "id": "W13lxPXn",
        "title": "Deterioration of MOVPE InN films on sapphire during growth and post-growth annealing",
        "abstract": "",
        "keywords": [
            "penetration depth"
        ],
        "authors": [
            {
                "name": "Hiroshi Miwa",
                "org": ""
            },
            {
                "name": "Akihiro Hashimoto",
                "org": ""
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                "org": ""
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        "year": 2006
    },
    "BilEnNny": {
        "id": "BilEnNny",
        "title": "Low temperature growth of GaN using catalyst\u2010assisted MOVPE",
        "abstract": "",
        "keywords": [
            "catalyst",
            "impurity",
            "movpe"
        ],
        "authors": [
            {
                "name": "kohei sasamoto",
                "org": "university of fukui"
            },
            {
                "name": "toru hotta",
                "org": "university of fukui"
            },
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                "name": "mikiyasu tanaka",
                "org": "university of fukui"
            },
            {
                "name": "kenichi sugita",
                "org": "university of fukui"
            },
            {
                "name": "a g bhuiyan",
                "org": "university of fukui"
            },
            {
                "name": "akihiro hashimoto",
                "org": "university of fukui"
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            {
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                "org": "university of fukui"
            }
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        "year": 2011
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    "N3RcdYQb": {
        "id": "N3RcdYQb",
        "title": "Recent advances in InN-based solar cells: status and challenges in InGaN and InAlN solar cells",
        "abstract": "",
        "keywords": [
            "movpe"
        ],
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Md. R. Islam",
                "org": ""
            },
            {
                "name": "Ting-Ting Kang",
                "org": ""
            },
            {
                "name": "Akihiro Hashimoto",
                "org": ""
            }
        ],
        "venue": "Physica Status Solidi (c)",
        "year": 2010
    },
    "o73K2C8A": {
        "id": "o73K2C8A",
        "title": "A comparative study of OMVPE-grown InN heteroepitaxial layers on GaAs(1 1 1)B and \u03b1-Al 2 O 3 (0 0 0 1) substrates",
        "abstract": "",
        "keywords": [
            "crystal structure",
            "inn"
        ],
        "authors": [
            {
                "name": "akio yamamoto",
                "org": ""
            },
            {
                "name": "yusuke yamauchi",
                "org": ""
            },
            {
                "name": "mitugu ohkubo",
                "org": ""
            },
            {
                "name": "akihiro hashimoto",
                "org": ""
            }
        ],
        "venue": "Journal of Crystal Growth",
        "year": 1997
    },
    "w61lsi33": {
        "id": "w61lsi33",
        "title": "Nitridation of In x Ga 1\u2212x As by dimethyl-hydrazine (DMHy)",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "akihiro hashimoto",
                "org": ""
            },
            {
                "name": "yoshitaka aiba",
                "org": ""
            },
            {
                "name": "yohichi kurumi",
                "org": ""
            },
            {
                "name": "akio yamamoto",
                "org": ""
            }
        ],
        "venue": "Journal of Crystal Growth",
        "year": 1998
    },
    "YKc7kqM0": {
        "id": "YKc7kqM0",
        "title": "Effect of gas flow on the growth of In-rich AlInN films by metal-organic chemical vapor deposition",
        "abstract": "",
        "keywords": [
            "thin film",
            "epitaxial growth",
            "phase diagram",
            "phase separation",
            "raman spectra"
        ],
        "authors": [
            {
                "name": "tingting kang",
                "org": "university of fukui"
            },
            {
                "name": "masatomo yamamoto",
                "org": "university of fukui"
            },
            {
                "name": "mikiyasu tanaka",
                "org": "university of fukui"
            },
            {
                "name": "akihiro hashimoto",
                "org": "university of fukui"
            },
            {
                "name": "akio yamamoto",
                "org": "university of fukui"
            },
            {
                "name": "\u4ead\u4ead \u5eb7",
                "org": "university of fukui"
            },
            {
                "name": "\u653f\u667a \u5c71\u672c",
                "org": "university of fukui"
            },
            {
                "name": "\u5e79\u5eb7 \u7530\u4e2d",
                "org": "university of fukui"
            },
            {
                "name": "\u660e\u5f18 \u6a4b\u672c",
                "org": "university of fukui"
            },
            {
                "name": "\u66a0\u52c7 \u5c71\u672c",
                "org": "university of fukui"
            }
        ],
        "venue": "Journal of Applied Physics",
        "year": 2009
    },
    "xKKHU7Vl": {
        "id": "xKKHU7Vl",
        "title": "Nitridation of GaAs(111) by dimethyl-hydrazine (DMHy) with As 4 molecular beam",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "akihiro hashimoto",
                "org": ""
            },
            {
                "name": "takanori motizuki",
                "org": ""
            },
            {
                "name": "yohichi kurumi",
                "org": ""
            },
            {
                "name": "akio yamamoto",
                "org": ""
            }
        ],
        "venue": "Journal of Crystal Growth",
        "year": 1998
    },
    "W1EB4yYb": {
        "id": "W1EB4yYb",
        "title": "Terahertz characterization of semiconductor alloy AlInN: negative imaginary conductivity and its meaning.",
        "abstract": "Through terahertz time-domain spectroscopy, negative imaginary conductivity is observed in In-rich AlInN film grown by metal-organic chemical-vapor deposition for frequencies from 0.2 to 2.0 THz. This non-Drude behavior is explained based on the electron back-scattering theory of Smith [Phys. Rev. B65, 115206 (2002)]. Comparing with binary semiconductor InN, potential fluctuations produced by composition inhomogeneity and alloy scattering of carriers make In-rich AlInN alloy easier to be subjected to non-Drude behavior in electrical performance.",
        "keywords": [
            "terahertz",
            "thin films"
        ],
        "authors": [
            {
                "name": "Ting-Ting Kang",
                "org": ""
            },
            {
                "name": "Masatomo Yamamoto",
                "org": ""
            },
            {
                "name": "Mikiyasu Tanaka",
                "org": ""
            },
            {
                "name": "Akihiro Hashimoto",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Ryota Sudo",
                "org": ""
            },
            {
                "name": "Akifumi Noda",
                "org": ""
            },
            {
                "name": "D. W. Liu",
                "org": ""
            },
            {
                "name": "Kohji Yamamoto",
                "org": ""
            }
        ],
        "venue": "Optics letters",
        "year": 2009
    },
    "bygr0cB5": {
        "id": "bygr0cB5",
        "title": "Nitridation effects of substrate surface on the metalorganic chemical vapor deposition growth of InN on Si and \u03b1-Al2O3 substrates",
        "abstract": "The metalorganic chemical vapor deposition (MOCVD) growth of InN has been studied using Si(111) and \u03b1-Al 2 O 3 (0001) substrates. An InN film grown on a Si substrate is poorly oriented, while a single-crystalline InN film is obtained on an \u03b1-Al 2 O 3 substrate in spite of the larger lattice mismatch for InN(0001)/\u03b1-Al 2 O 3 (0001) than that for InN(0001)/Si(111). Such a remarkable difference in InN film quality between Si and \u03b1-Al 2 O 3 substrates is found to be brought on by the nitridation of the substrate surface before the growth. It has been revealed from reflection high-energy electron diffraction (RHEED) and electron spectroscopy for chemical analysis (ESCA) analyses that silicon nitride of amorphous phase is formed on a Si(111) surface at a relatively low temperature (\u2248500\u00b0C), which prevents the growth of heteroepitaxial InN on Si. Nitridation of \u03b1-Al 2 O 3 surface occurs at a temperature higher than 800\u00b0C, and brings about a remarkable improvement of heteroepitaxial InN quality. This is because an AlN is formed and the lattice mismatch is reduced from 25% for InN/\u03b1-Al 2 O 3 to about 13% for InN/AlN.",
        "keywords": [
            "surface temperature"
        ],
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Mitsunori Tsujino",
                "org": "Department of Electrical and Electronics Engineering, Faculty of Engineering, Fukui University, 3-9-1 Bunkyo, Fukui, Fukui 910, Japan"
            },
            {
                "name": "Mitsugu Ohkubo",
                "org": "Department of Electrical and Electronics Engineering, Faculty of Engineering, Fukui University, 3-9-1 Bunkyo, Fukui, Fukui 910, Japan"
            },
            {
                "name": "Akihiro Hashimoto",
                "org": "Department of Electrical and Electronics Engineering, Faculty of Engineering, Fukui University, 3-9-1 Bunkyo, Fukui, Fukui 910, Japan"
            }
        ],
        "venue": "Journal of Crystal Growth",
        "year": 1994
    },
    "G83YeHeC": {
        "id": "G83YeHeC",
        "title": "Inhomogeneities in MOVPE InN",
        "abstract": "",
        "keywords": [
            "atmospheric pressure",
            "spectrum",
            "near field"
        ],
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Hiroshi Miwa",
                "org": ""
            },
            {
                "name": "Wen Jun Wang",
                "org": ""
            },
            {
                "name": "Akihiro Hashimoto",
                "org": ""
            }
        ],
        "venue": "Physica Status Solidi (a)",
        "year": 2006
    },
    "A3x9JgMm": {
        "id": "A3x9JgMm",
        "title": "MOVPE growth of thick (\u223c1 \u00b5m) InGaN on AlN/Si substrates for InGaN/Si tandem solar cells",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "akio yamamoto",
                "org": "university of fukui"
            },
            {
                "name": "kazuki kodama",
                "org": "university of fukui"
            },
            {
                "name": "md tanvir hasan",
                "org": "university of fukui"
            },
            {
                "name": "naoteru shigekawa",
                "org": "osaka city university"
            },
            {
                "name": "masaaki kuzuhara",
                "org": "university of fukui"
            }
        ],
        "venue": "Japanese Journal of Applied Physics",
        "year": 2015
    },
    "PjPUmAzw": {
        "id": "PjPUmAzw",
        "title": "Effects of RIE-damaged layer removal on electrical properties of AlGaN/GaN structures prepared by AlGaN regrowth on RIE-GaN surface",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Keito Kanatani",
                "org": ""
            },
            {
                "name": "Shinya Makino",
                "org": ""
            },
            {
                "name": "Masaaki Kuzuhara",
                "org": ""
            }
        ],
        "venue": "The Japan Society of Applied Physics",
        "year": 2018
    },
    "FebHmiRg": {
        "id": "FebHmiRg",
        "title": "Mg doping behavior of NH 3 decomposition catalyst-assisted MOVPE In x Ga 1-x N (x~0.35)",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Kazuki Kodama",
                "org": ""
            },
            {
                "name": "Naoteru Shigekawa",
                "org": ""
            },
            {
                "name": "Takashi Matsuoka",
                "org": ""
            },
            {
                "name": "Masaaki Kuzuhara",
                "org": ""
            }
        ],
        "venue": "The Japan Society of Applied Physics",
        "year": 2016
    },
    "vlgMQY9A": {
        "id": "vlgMQY9A",
        "title": "Low-temperature (\u2265400 \u00b0C) growth of InN by metalorganic vapor phase epitaxy using an NH3 decomposition catalyst",
        "abstract": "In this paper, we report the metalorganic vapor phase epitaxial (MOVPE) growth of InN using a NiO-based pellet-type NH3 decomposition catalyst. The use of the catalyst significantly changes the growth behavior of InN, which is dependent on the growth temperature (T g). Continuous InN films without the incorporation of metallic In and a cubic phase are grown at T g = 400\u2013480 \u00b0C. An InN film grown at T g \u2248 450 \u00b0C has a full-width at half maximum (FWHM) of 376 arcsec in the X-ray rocking curve for InN(0002) reflection. At T g \u2265 500 \u00b0C, the deposition rate of InN rapidly decreases and the deposited films become discontinuous with large (ca. 1 \u00b5m) pyramidal grains of InN. Depositions are scarcely obtained at T g \u2265 600 \u00b0C. Such changes in the growth behavior of InN are governed by the NH3 decomposition.",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": "University of Fukui, Fukui 910-8507, Japan"
            },
            {
                "name": "Kazuki Kodama",
                "org": "University of Fukui, Fukui 910-8507, Japan"
            },
            {
                "name": "Naoteru Shigekawa",
                "org": "Osaka City University, Osaka 558-8585, Japan"
            },
            {
                "name": "Takashi Matsuoka",
                "org": "IMR, Tohoku University, Sendai 980-8577, Japan"
            },
            {
                "name": "Masaaki Kuzuhara",
                "org": "University of Fukui, Fukui 910-8507, Japan"
            }
        ],
        "venue": "Japanese Journal of Applied Physics",
        "year": 2016
    },
    "61j0No7q": {
        "id": "61j0No7q",
        "title": "Low-temperature (\u2264600 \u00b0C) growth of high-quality In x Ga1\u2212 x N (x \u223c 0.3) by metalorganic vapor phase epitaxy using NH3 decomposition catalyst",
        "abstract": "In x Ga1\u2212 x N (x ~ 0.3) films on GaN/sapphire templates were grown by NH3 decomposition catalyst-assisted metalorganic vapor phase epitaxy (CA-MOVPE). NiO-based pellets were used as a catalyst. Even at a temperature lower than 500 \u00b0C, single-crystal In0.3Ga0.7N films were grown without the incorporation of metallic components (In, Ga) or the cubic phase. In contrast with the case of InN growth using the same catalyst [A. Yamamoto et al., Jpn. J. Appl. Phys. 55, 05FD04 (2016)], no marked grain growth or hydrogen etching was observed in In0.3Ga0.7N. Samples grown at a temperature \u2264500 \u00b0C showed a full-width at half-maximum of the (0002) X-ray rocking curve as small as 10 arcmin or smaller. The carrier concentration in nominally undoped In0.3Ga0.7N grown using the catalyst was higher by about 4 orders of magnitude than that in conventional MOVPE samples. Secondary ion mass spectroscopy analysis revealed that such a higher carrier concentration was due to the marked reduction in carbon contamination level in the films.",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": "Graduate School of Engineering, University of Fukui, Fukui 910-8507, Japan"
            },
            {
                "name": "Kazuki Kodama",
                "org": "Graduate School of Engineering, University of Fukui, Fukui 910-8507, Japan"
            },
            {
                "name": "Takashi Matsuoka",
                "org": "Institute of Materials Research, Tohoku University, Sendai 980-8577, Japan"
            },
            {
                "name": "Masaaki Kuzuhara",
                "org": "Graduate School of Engineering, University of Fukui, Fukui 910-8507, Japan"
            }
        ],
        "venue": "Japanese Journal of Applied Physics",
        "year": 2017
    },
    "3unrjTEF": {
        "id": "3unrjTEF",
        "title": "AlGaN/GaN heterostructures with an AlGaN layer grown directly on reactive-ion-etched GaN showing a high electron mobility (>1300 cm2 V\u22121 s\u22121)",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Shinya Makino",
                "org": ""
            },
            {
                "name": "Keito Kanatani",
                "org": ""
            },
            {
                "name": "Masaaki Kuzuhara",
                "org": ""
            }
        ],
        "venue": "Japanese Journal of Applied Physics",
        "year": 2018
    },
    "gv2D70dE": {
        "id": "gv2D70dE",
        "title": "Metalorganic vapor phase epitaxial growth of AlGaN directly on reactive-ion etching-treated GaN surfaces to prepare AlGaN/GaN heterostructures with high electron mobility (\u223c1500 cm2 V\u22121 s\u22121): Impacts of reactive-ion etching-damaged layer removal",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Keito Kanatani",
                "org": ""
            },
            {
                "name": "Shinya Makino",
                "org": ""
            },
            {
                "name": "Masaaki Kuzuhara",
                "org": ""
            }
        ],
        "venue": "Japanese Journal of Applied Physics",
        "year": 2018
    },
    "d32e86Ip": {
        "id": "d32e86Ip",
        "title": "Latest progress in the MOVPE growth of indium nitride (InN) film",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Ashraful G. Bhuiyan",
                "org": ""
            },
            {
                "name": "Akihiro Hashimoto",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "IEICE technical report. Electron devices",
        "year": 2002
    },
    "15CDpGdD": {
        "id": "15CDpGdD",
        "title": "Photocatalytic H_2S decomposition by InN_ O_x films grown by ArF laser-assisted MOCVD",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Masayoshi Miyanishi",
                "org": ""
            },
            {
                "name": "Naoya Takahashi",
                "org": ""
            },
            {
                "name": "Takahiro Kobayashi",
                "org": ""
            },
            {
                "name": "Katsumi Takayama",
                "org": ""
            },
            {
                "name": "Yukio Nambo",
                "org": ""
            },
            {
                "name": "Akihiro Hashimoto",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "IEICE technical report. Component parts and materials",
        "year": 2005
    },
    "qpClQDuv": {
        "id": "qpClQDuv",
        "title": "Observation of superconducting phase transition in InN",
        "abstract": "InN superconductivity is very special among III-V semiconductors, because other III-V semiconductor (like GaAs, GaN, InP, InAs etc.) usually lacks strong covalent bonding and seldom shows superconductivity at low-temperature. In this paper, via current-voltage(I-V) measurement, we probe the superconducting phase transitions in InN. The possible connection with those chemical-unstable phase separated inclusions, like metallic indium or In2O3, was removed by HCl acid etching. It finds InN samples can show different phase transition behaviors. The vortex-glass (VG) to liquid transition, which is typical in type-II superconductors, is observed in the sample with large InN grain size. In contrast, the small grain-sized sampleu0027s superconducting properties are sensitive to acid etching, shows a transition into a non-zero resistance state at the limit of temperature approaches zero. Our work suggests that the grain size and inter-grain coupling may be two key factors for realizing InN superconductivity. InN superconductivity can become robust and chemical stable if the grain size and inter-grain coupling both are large enough.",
        "keywords": "",
        "authors": [
            {
                "name": "Zhi-Yong Song",
                "org": ""
            },
            {
                "name": "Liyan Shang",
                "org": ""
            },
            {
                "name": "JunHao Chu",
                "org": ""
            },
            {
                "name": "Ping-Ping Chen",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Ting-Ting Kang",
                "org": ""
            }
        ],
        "venue": "arXiv: Mesoscale and Nanoscale Physics",
        "year": 2019
    },
    "nQTErTDX": {
        "id": "nQTErTDX",
        "title": "SELECTIVE CLEAVAGE OF CARBON-OXYGEN BONDS IN ESTERS THROUGH OXIDATIVE ADDITION TO NICKEL(0) COMPLEXES",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Junichi Ishizu",
                "org": ""
            },
            {
                "name": "Takakazu Yamamoto",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "ChemInform",
        "year": 1977
    },
    "Ggd2nhLF": {
        "id": "Ggd2nhLF",
        "title": "REVERSIBLE CARBONYL INSERTION INTO A NICKEL-CARBON BOND OF ALKYL(ACETYLACETONATO)(TRIPHENYLPHOSPHINE)NICKEL(II)",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Toshio Saruyama",
                "org": ""
            },
            {
                "name": "Takakazu Yamamoto",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "ChemInform",
        "year": 1976
    },
    "0XY3wZ6A": {
        "id": "0XY3wZ6A",
        "title": "PREPARATION AND PROPERTIES OF A NONRIGID ETHYL NICKEL COMPLEX, NIC2H5(ACAC)(PPH3), AND ITS METHYL ANALOG, NICH3(ACAC)(PPH3)2",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Takakazu Yamamoto",
                "org": ""
            },
            {
                "name": "Toshio Saruyama",
                "org": ""
            },
            {
                "name": "Yoshiyuki Nakamura",
                "org": ""
            }
        ],
        "venue": "ChemInform",
        "year": 1973
    },
    "Okf1h66l": {
        "id": "Okf1h66l",
        "title": "Selective Formation of Ketone, Diketone and Aldehyde by the CO Insertion into Nickel-Alkyl Bonds of Dialkylnickel Complexes. A Novel Nickel-Catalyzed Synthesis of Ketones and Tertiary Alcohols from Grignard Reagents, Aryl Halides, and",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Takakazu Yamamoto",
                "org": ""
            },
            {
                "name": "Teiji Kohara",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "ChemInform",
        "year": 1977
    },
    "gty2Nugt": {
        "id": "gty2Nugt",
        "title": "PREPARATION OF NEW ALKYLCHROMIUM COMPLEXES RCRCL2(BASE)N (R = METHYL, ETHYL) AND EFFECTS OF THE BASE ON THEIR THERMAL STABILITY",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Y. Kano",
                "org": ""
            },
            {
                "name": "Takakazu Yamamoto",
                "org": ""
            }
        ],
        "venue": "ChemInform",
        "year": 1976
    },
    "Sj6JnK79": {
        "id": "Sj6JnK79",
        "title": "PREPARATION OF SEVERAL NEW NICKEL- OR PALLADIUM-CONTAINING CYCLIC AMIDES AND ESTERS AND RING CONTRACTION OF THE SIX-MEMBERED NICKEL-CONTAINING CYCLIC ESTER TO ITS FIVE-MEMBERED ISOMER",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "K. Sano",
                "org": ""
            },
            {
                "name": "Takakazu Yamamoto",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "ChemInform",
        "year": 1982
    },
    "xNbDr8E0": {
        "id": "xNbDr8E0",
        "title": "PREPARATION OF NEW PLATINUM- AND NICKEL-CONTAINING CYCLIC ESTERS AND THEIR REACTIVITIES",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "K. Sano",
                "org": ""
            },
            {
                "name": "Takakazu Yamamoto",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "ChemInform",
        "year": 1983
    },
    "kFGjhWj1": {
        "id": "kFGjhWj1",
        "title": "A NEW SELECTIVE CARBON-SULFUR BOND CLEAVAGE REACTION OF SULFIDES PROMOTED BY A RHODIUM HYDRIDE COMPLEX",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Kohtaro Osakada",
                "org": ""
            },
            {
                "name": "K. Matsumoto",
                "org": ""
            },
            {
                "name": "Takakazu Yamamoto",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "ChemInform",
        "year": 1985
    },
    "SQN8ks8y": {
        "id": "SQN8ks8y",
        "title": "Chemistry of Organopalladium Complexes Related to Catalytic Double Carbonylation Reactions",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Fumiyuki Ozawa",
                "org": ""
            },
            {
                "name": "Hiroshi Nakazawa",
                "org": ""
            },
            {
                "name": "Takakazu Yamamoto",
                "org": ""
            }
        ],
        "venue": "ChemInform",
        "year": 1985
    },
    "M4Dn9Vs4": {
        "id": "M4Dn9Vs4",
        "title": "LITHIUM/LITHIUM IODIDE/IODINE GALVANIC CELLS USING IODINE-NYLON-6 ADDUCTS AS POSITIVE ELECTRODES",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Takakazu Yamamoto",
                "org": ""
            },
            {
                "name": "M. Hishinuma",
                "org": ""
            },
            {
                "name": "Kohtaro Osakada",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "ChemInform",
        "year": 1984
    },
    "aNpTQABR": {
        "id": "aNpTQABR",
        "title": "REGIOSELECTIVE CARBON-OXYGEN BOND CLEAVAGE OF ALLYLIC PHENYL CARBONATES PROMOTED BY GROUP 8 TRANSITION METAL HYDRIDO COMPLEXES",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Y. Hayashi",
                "org": ""
            },
            {
                "name": "Sanshiro Komiya",
                "org": ""
            },
            {
                "name": "Takakazu Yamamoto",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "ChemInform",
        "year": 1985
    },
    "ZULM6K0d": {
        "id": "ZULM6K0d",
        "title": "Carbon - Oxygen Bond Cleavage of Esters Promoted by Hydrido and Alkylcobalt(I) Complexes Having Triphenylphosphine Ligands. Isolation of an Insertion Intermediate and Molecular Structure of Phenoxotris(triphenylphosphine)cobalt(I).",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Y. Hayashi",
                "org": ""
            },
            {
                "name": "Takakazu Yamamoto",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Sanshiro Komiya",
                "org": ""
            },
            {
                "name": "Yoshihiko Kushi",
                "org": ""
            }
        ],
        "venue": "ChemInform",
        "year": 1986
    },
    "P1TwcTch": {
        "id": "P1TwcTch",
        "title": "Preparation and properties of new methyl(alkoxo)- and methyl(thiolato)nickel and methyl(alkoxo)- and methyl(thiolato)palladium complexes: CO and CS2 insertion into the alkoxo-palladium bond",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Yong-Joo Kim",
                "org": ""
            },
            {
                "name": "Kohtaro Osakada",
                "org": ""
            },
            {
                "name": "K. Sugita",
                "org": ""
            },
            {
                "name": "Takakazu Yamamoto",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "Organometallics",
        "year": 1988
    },
    "WsP5eeeK": {
        "id": "WsP5eeeK",
        "title": "Effect of Ligand on Ring Contraction of Six-Membered Nickel-Containing Cyclic Esters, Cyclic LnNiCH2CH2CH2COO, to Their Five-Membered-Ring Isomers, Cyclic LnNiCH(CH3)CH2COO. Kinetic and Thermodynamic Control of Asymmetric Induction by",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Takakazu Yamamoto",
                "org": ""
            },
            {
                "name": "K. Sano",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "ChemInform",
        "year": 1987
    },
    "SXhkQWNV": {
        "id": "SXhkQWNV",
        "title": "C-H and C-O Bond Activation by Transition Metal Complexes. Oxidative Addition and Reductive Elimination.",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Sanshiro Komiya",
                "org": "Research Laboratory of Resources Utilization, Tokyo Institute of Technology"
            },
            {
                "name": "Akio Yamamoto",
                "org": "Research Laboratory of Resources Utilization, Tokyo Institute of Technology"
            },
            {
                "name": "Takakazu Yamamoto",
                "org": "Research Laboratory of Resources Utilization, Tokyo Institute of Technology"
            }
        ],
        "venue": "Journal of Synthetic Organic Chemistry Japan",
        "year": 1980
    },
    "jTcj5XQa": {
        "id": "jTcj5XQa",
        "title": "ZINC!ZINC IODIDE!IODINE SECONDARY GALVANIC CELLS USING IODINE ADDUCTS OF NYLON-6 AND OTHER POLYMERS AS POSITIVE ELECTRODES",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Takakazu Yamamoto",
                "org": ""
            },
            {
                "name": "M. Hishinuma",
                "org": ""
            },
            {
                "name": "H. Sugimoto",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "H. Sukawa",
                "org": ""
            }
        ],
        "venue": "ChemInform",
        "year": 1985
    },
    "vBbCB9hP": {
        "id": "vBbCB9hP",
        "title": "Preparation and Properties of NickelPhosphine Complexes Coordinated with a,-Unsaturated Ester",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Junichi Ishizu",
                "org": ""
            },
            {
                "name": "Takakazu Yamamoto",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "Bulletin of the Chemical Society of Japan",
        "year": 1978
    },
    "xOc2y64H": {
        "id": "xOc2y64H",
        "title": "Organonickel, -palladium and -platinum Complexes.",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Takakazu Yamamoto",
                "org": ""
            },
            {
                "name": "Fumiyuki Ozawa",
                "org": ""
            }
        ],
        "venue": "Journal of Synthetic Organic Chemistry Japan",
        "year": 1983
    },
    "td7R4UH2": {
        "id": "td7R4UH2",
        "title": "CARBON-HYDROGEN BOND CLEAVAGE IN ALKENYL CARBOXYLATES PROMOTED BY METHYLCOPPER COMPLEXES AND FORMATION OF SIX-MEMBERED ACETOXYVINYLCOPPER CHELATES",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Minoru Kubota",
                "org": ""
            },
            {
                "name": "Akira Miyashita",
                "org": ""
            },
            {
                "name": "S. Komiya",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "ChemInform",
        "year": 1978
    },
    "LrIBCtJN": {
        "id": "LrIBCtJN",
        "title": "STUDIES ON THE REACTIONS OF BIS(ACETYLACETONATO)PLATINUM(II) WITH LEWIS BASES. I. REACTIONS WITH TERTIARY PHOSPHINES LEADING TO A COMPLEX CONTAININ CARBON-BONDED UNIDENTATE ACETYLACETONATO LIGAND AND PREPARATION OF NE ALKYLPLATINUM CO",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Takashi Ito",
                "org": ""
            },
            {
                "name": "T. Kiriyama",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "ChemInform",
        "year": 1977
    },
    "1WZijO6w": {
        "id": "1WZijO6w",
        "title": "CARBON-CYANO (C-CN) BOND CLEAVAGE UNDER MILD CONDITIONS PROMOTED BY ELECTRON-RICH COBALT COMPLEXES",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Fumiyuki Ozawa",
                "org": ""
            },
            {
                "name": "K. Iri",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "ChemInform",
        "year": 1983
    },
    "fBpDkkHI": {
        "id": "fBpDkkHI",
        "title": "DIALKYLPALLADIUM(II) COMPLEXES. SYNTHESES, CHARACTERIZATIONS, AND REACTIONS WITH CARBON MONOXIDE, IODINE, AND METHYL IODIDE",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Takashi Ito",
                "org": ""
            },
            {
                "name": "H. Tsuchiya",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "ChemInform",
        "year": 1977
    },
    "QIU5IC5f": {
        "id": "QIU5IC5f",
        "title": "KINETIK UND STOECHIOMETRIE DER STICKSTOFF-FIXIERUNG MIT TICL3-MG- UND VCL3-MG-SYST. IN TETRAHYDROFURAN",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Shigeo Go",
                "org": ""
            },
            {
                "name": "Masaharu Ookawa",
                "org": ""
            },
            {
                "name": "Mitsuaki Takahashi",
                "org": ""
            },
            {
                "name": "Sakuji Ikeda",
                "org": ""
            },
            {
                "name": "Tominaga Keii",
                "org": ""
            }
        ],
        "venue": "ChemInform",
        "year": 1973
    },
    "l9jY9KNj": {
        "id": "l9jY9KNj",
        "title": "STYROL- UND AETHYLEN-KOMPLEXE DES RUTHENIUMS ALS AKTIVE ZWISCHENSTUFEN BEI DER KATALYTISCHEN HYDRIERUNG VON OLEFINEN",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Sanshiro Komiya",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Sakuji Ikeda",
                "org": ""
            }
        ],
        "venue": "ChemInform",
        "year": 1973
    },
    "t7BopG9T": {
        "id": "t7BopG9T",
        "title": "DARST. UND EIGENSCHAFTEN VON DIMETHYL-TRIS-(TRIPHENYLPHOSPHIN)-EISEN(II) UND AETHYL-(ACETYLACETONATO)-TRIS-(TRIPHENYLPHOSPHIN)-EISEN(II)",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Yoichiro Kubo",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Sakuji Ikeda",
                "org": ""
            }
        ],
        "venue": "ChemInform",
        "year": 1973
    },
    "lc0bc1nU": {
        "id": "lc0bc1nU",
        "title": "HERST. EINES PHENYL-NICKEL-KOMPLEXES, PHENYL-(DIPYRIDYL)-NICKEL, DER DIE OLEFIN-DIMERISIERUNG KATALYSIERT",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "M. Uchino",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Sakuji Ikeda",
                "org": ""
            }
        ],
        "venue": "ChemInform",
        "year": 1970
    },
    "HzmXAB36": {
        "id": "HzmXAB36",
        "title": "MECHANISMUS DER POLYMERISATION VON VINYLVERBINDUNGEN DURCH DI-(C1-C3-N-ALKYL)-BIS-(DIPYRIDYL)-EISEN(II)",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Takakazu Yamomoto",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Sakuji Ikeda",
                "org": ""
            }
        ],
        "venue": "ChemInform",
        "year": 1972
    },
    "KtxB2Uyj": {
        "id": "KtxB2Uyj",
        "title": "STICKSTOFF-KOORDINIERTE KOMPLEXE, DARST. UND RK. DER HYDRIDO-PHOSPHIN-KOMPLEXE VON RUTHENIUM UND RHODIUM",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Takashi Ito",
                "org": ""
            },
            {
                "name": "Shoji. Kitazume",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Sakuji Ikeda",
                "org": ""
            }
        ],
        "venue": "ChemInform",
        "year": 1970
    },
    "ileUKdWK": {
        "id": "ileUKdWK",
        "title": "ORGANO-DIPYRIDYL-NICKEL-KOMPLEXE 1. MITT. STABILITAET VON DIALKYL-DIPYRIDYL-NICKEL(II) (KOORDINATION MIT OLEFINEN) 2. MITT. STABILITAET VON DIPYRIDYL- UND DIALKYL-DIPYRIDYL-NICKEL-KOMPLEXEN MIT OLEFINLIGANDEN",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Takakazu Yamamoto",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Sakuji Ikeda",
                "org": ""
            }
        ],
        "venue": "ChemInform",
        "year": 1971
    },
    "ugXxvnBL": {
        "id": "ugXxvnBL",
        "title": "DARST. UND EIGENSCHAFTEN VON METHYL-(TRIPHENYLPHOSPHIN)-KUPFER-KOMPLEXEN",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Akira Miyashita",
                "org": ""
            },
            {
                "name": "Takakazu Yamamoto",
                "org": ""
            },
            {
                "name": "Sakuji Ikeda",
                "org": ""
            }
        ],
        "venue": "ChemInform",
        "year": 1972
    },
    "VFIR0ctG": {
        "id": "VFIR0ctG",
        "title": "DARST. UND EIGENSCHAFTEN VON ALKYLCHROMDICHLORID-KOMPLEXEN",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "K. Nishimura",
                "org": ""
            },
            {
                "name": "H. Kuribayashi",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Sakuji Ikeda",
                "org": ""
            }
        ],
        "venue": "ChemInform",
        "year": 1972
    },
    "8ONmZnzY": {
        "id": "8ONmZnzY",
        "title": "AKTIVIERUNG VON EISEN-ALKYL-BINDUNGEN IN DIALKYL-BIS-(BIPYRIDYL)-EISEN(II) DURCH WECHSELWIRKUNG MIT OLEFINEN",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Takakazu Yamamoto",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Sakuji Ikeda",
                "org": ""
            }
        ],
        "venue": "ChemInform",
        "year": 1972
    },
    "AAxrz67e": {
        "id": "AAxrz67e",
        "title": "SYNTH. UND EIGENSCHAFTEN VON HYDRIDODISTICKSTOFF-TRIS-(TRIPHENYLPHOSPHIN)-KOBALT(I) UND VERWANDTEN PHOSPHIN-KOBALT-KOMPLEXEN",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Shoji. Kitazume",
                "org": ""
            },
            {
                "name": "Lyong Sun Pu",
                "org": ""
            },
            {
                "name": "Sakuji Ikeda",
                "org": ""
            }
        ],
        "venue": "ChemInform",
        "year": 1971
    },
    "Ag4OHAS3": {
        "id": "Ag4OHAS3",
        "title": "Enhancement of power factor by energy filtering effect in Re substituted HMS",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Swapnil Ghodke",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Hiroshi Ikuta",
                "org": ""
            },
            {
                "name": "Tsunehiro Takeuchi",
                "org": ""
            }
        ],
        "venue": "The Japan Society of Applied Physics",
        "year": 2016
    },
    "FSM1psM8": {
        "id": "FSM1psM8",
        "title": "Thermoelectric properties of super-saturated Cr-doped MnSiy",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Swapnil Ghodke",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Muthusamy Omprakash",
                "org": ""
            },
            {
                "name": "Hiroshi Ikuta",
                "org": ""
            },
            {
                "name": "Tsunehiro Takeuchi",
                "org": ""
            }
        ],
        "venue": "The Japan Society of Applied Physics",
        "year": 2016
    },
    "MpE8faVu": {
        "id": "MpE8faVu",
        "title": "Thermoelectric properties of FeVSb half-Heusler by predicting from the electronic structure and the scattering proberbility of electrons",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": "Toyota Tech. Inst."
            },
            {
                "name": "Tatsuya Yamada",
                "org": "Toyota Tech. Inst."
            },
            {
                "name": "Tsunehiro Takeuchi",
                "org": "Toyota Tech. Inst."
            }
        ],
        "venue": "The Japan Society of Applied Physics",
        "year": 2016
    },
    "g878PRk0": {
        "id": "g878PRk0",
        "title": "Thermoelectric properties of half Heusler FeV 1-x Ti x Sb",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Kevin Delime",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Tsunehiro Takeuchi",
                "org": ""
            }
        ],
        "venue": "The Japan Society of Applied Physics",
        "year": 2017
    },
    "Ix4i4KG9": {
        "id": "Ix4i4KG9",
        "title": "Thermal conductivity measurement of ribbon-shaped MnSi \u03b3 using cyclic heat method",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Shunsuke Nishino",
                "org": ""
            },
            {
                "name": "Swapnil Ghodke",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Tsunehiro Takeuchi",
                "org": ""
            }
        ],
        "venue": "The Japan Society of Applied Physics",
        "year": 2016
    },
    "69jygrm7": {
        "id": "69jygrm7",
        "title": "Thermoelectric properties of supersaturated Re solid solution of higher manganese silicides",
        "abstract": "In this study, we developed a higher manganese silicide (HMS) that possesses a high dimensionless figure of merit ZT exceeding unity. HMSs containing a larger amount of Re than its solubility limit were prepared by the liquid quenching technique, and the obtained metastable HMSs showed good thermal stability to enable pulse current sintering at 1240 K. The lattice thermal conductivity was effectively reduced with increasing Re concentration, whereas the electron transport properties were not greatly affected. Consequently, the ZT of p-type HMS increased to 1.04 at 6 at. % Re from 0.4 of the Re-free sample.",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": "Toyota Technological Institute, Nagoya 468-8511, Japan"
            },
            {
                "name": "Swapnil Ghodke",
                "org": "Department of Crystalline Materials Science, Nagoya University, Nagoya 464-8603, Japan"
            },
            {
                "name": "Hidetoshi Miyazaki",
                "org": "Department of Frontier Materials, Nagoya Institute of Technology, Nagoya 466-8555, Japan"
            },
            {
                "name": "Manabu Inukai",
                "org": "Department of Frontier Materials, Nagoya Institute of Technology, Nagoya 466-8555, Japan"
            },
            {
                "name": "Yoichi Nishino",
                "org": "Department of Frontier Materials, Nagoya Institute of Technology, Nagoya 466-8555, Japan"
            },
            {
                "name": "M. Matsunami",
                "org": "Department of Frontier Materials, Nagoya Institute of Technology, Nagoya 466-8555, Japan"
            },
            {
                "name": "Tsunehiro Takeuchi",
                "org": "Toyota Technological Institute, Nagoya 468-8511, Japan"
            },
            {
                "name": "Tsunehiro Takeuchi",
                "org": "Toyota Technological Institute, Nagoya 468-8511, Japan"
            },
            {
                "name": "Tsunehiro Takeuchi",
                "org": "Toyota Technological Institute, Nagoya 468-8511, Japan"
            }
        ],
        "venue": "Japanese Journal of Applied Physics",
        "year": 2016
    },
    "e405IPQ3": {
        "id": "e405IPQ3",
        "title": "Development of Thermoelectric Materials Consisting Solely of Environmental Friendly Elements",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Tsunehiro Takeuchi",
                "org": "Toyota Technological Institute"
            },
            {
                "name": "Tsunehiro Takeuchi",
                "org": "Toyota Technological Institute"
            },
            {
                "name": "Tsunehiro Takeuchi",
                "org": "Toyota Technological Institute"
            },
            {
                "name": "Akio Yamamoto",
                "org": "Toyota Technological Institute"
            },
            {
                "name": "Swapnil Ghodke",
                "org": "Department of Crystalline Materials Science, Nagoya University"
            }
        ],
        "venue": "Materials Transactions",
        "year": 2016
    },
    "d8UdADGC": {
        "id": "d8UdADGC",
        "title": "Thermoelectric Properties of Al-Mn-Si Based C54 Phase Containing Small Amount of C40 Phase",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": "Toyota Technological Institute"
            },
            {
                "name": "Swapnil Ghodke",
                "org": "Department of Crystalline Materials Science, Nagoya University"
            },
            {
                "name": "Hidetoshi Miyazaki",
                "org": "Department of Frontier Materials, Nagoya Institute of Technology"
            },
            {
                "name": "Yoichi Nishino",
                "org": "Department of Frontier Materials, Nagoya Institute of Technology"
            },
            {
                "name": "M. Matsunami",
                "org": ""
            },
            {
                "name": "Tsunehiro Takeuchi",
                "org": "Toyota Technological Institute"
            },
            {
                "name": "Tsunehiro Takeuchi",
                "org": "Toyota Technological Institute"
            },
            {
                "name": "Tsunehiro Takeuchi",
                "org": "Toyota Technological Institute"
            }
        ],
        "venue": "Materials Transactions",
        "year": 2016
    },
    "o9fSC2ol": {
        "id": "o9fSC2ol",
        "title": "The Potential of FeVSb Half-Heusler Phase for Practical Thermoelectric Material",
        "abstract": "The electronic structure and electron transport properties of FeVSb half-Heusler phase were calculated using first-principles calculations and Boltzmann transport equation. We found, as a result of theoretical calculations, that the magnitude of the dimensionless of figure of merit (ZT) could be increased up to \u223c0.84 due to the drastic increase of the power factor when the carrier concentration of p-type FeVSb is optimized through element substitution to vary the valence electron concentration. We revealed that this large increase in ZT is closely related to the significant variations both in electronic density of states and spectral conductivity with decreasing energy at the top of the valence band.",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": "Toyota Technological Institute"
            },
            {
                "name": "Tsunehiro Takeuchi",
                "org": "Toyota Technological Institute"
            },
            {
                "name": "Tsunehiro Takeuchi",
                "org": "Toyota Technological Institute"
            }
        ],
        "venue": "Journal of Electronic Materials",
        "year": 2017
    },
    "cAypzDgQ": {
        "id": "cAypzDgQ",
        "title": "Development of amorphous bulk Al-Mn-Si for nano-structured thermoelectric materials",
        "abstract": "Abstract   In this study, we have developed amorphous bulk in the Al-Mn-Si alloy system as a precursor of thermoelectric materials consisting of nano-grains. The quenched ribbon samples at the composition of Al 34.4 Mn 21.2 Si 44.4  became single amorphous phase. By applying approximately 3 GPa at room temperature, we succeeded in preparing bulk amorphous samples without possessing any other crystalline phases.",
        "keywords": "",
        "authors": [
            {
                "name": "Masahiro Adachi",
                "org": "Semiconductor Materials Department, Sumitomo Electric Industries, Ltd., 1-1-1, Koyakita, Itami-shi, Hyogo 664-0016, Japan"
            },
            {
                "name": "Shunsuke Fujii",
                "org": "Semiconductor Materials Department, Sumitomo Electric Industries, Ltd., 1-1-1, Koyakita, Itami-shi, Hyogo 664-0016, Japan"
            },
            {
                "name": "Makoto Kiyama",
                "org": "Semiconductor Materials Department, Sumitomo Electric Industries, Ltd., 1-1-1, Koyakita, Itami-shi, Hyogo 664-0016, Japan"
            },
            {
                "name": "Yoshiyuki Yamamoto",
                "org": "Semiconductor Materials Department, Sumitomo Electric Industries, Ltd., 1-1-1, Koyakita, Itami-shi, Hyogo 664-0016, Japan"
            },
            {
                "name": "Shunsuke Nishino",
                "org": "Energy Materials Laboratory, Toyota Technological Institute, 2-12-1 Hisakata Tempaku-ku, Nagoya 468-8511, Japan"
            },
            {
                "name": "Muthusamy Omprakash",
                "org": "Energy Materials Laboratory, Toyota Technological Institute, 2-12-1 Hisakata Tempaku-ku, Nagoya 468-8511, Japan"
            },
            {
                "name": "Akio Yamamoto",
                "org": "Energy Materials Laboratory, Toyota Technological Institute, 2-12-1 Hisakata Tempaku-ku, Nagoya 468-8511, Japan"
            },
            {
                "name": "Akihiro Makino",
                "org": ""
            },
            {
                "name": "Tsunehiro Takeuchi",
                "org": "Energy Materials Laboratory, Toyota Technological Institute, 2-12-1 Hisakata Tempaku-ku, Nagoya 468-8511, Japan"
            }
        ],
        "venue": "Materials Today: Proceedings",
        "year": 2018
    },
    "EHwBJXqR": {
        "id": "EHwBJXqR",
        "title": "Enhanced Thermoelectric Properties of W- and Fe-Substituted MnSi\u03b3",
        "abstract": "We have investigated the effect of heavy-element (W) substitution on the thermoelectric properties of higher manganese silicide (HMS). Samples were prepared by arc melting followed by liquid quenching, where the latter assisted in achieving higher solubility for tungsten. We observed that Mn34.6W1.8Si63.6 was a p-type material, whereas simultaneous substitution of 12 at.% Fe made the higher manganese silicide an n-type material. The optimal carrier concentration was obtained by simultaneous substitution of Fe and W for Mn atoms. Although the samples were metastable, we successfully obtained bulk samples by a low-temperature (970 K), high-pressure (u003e100 MPa), long-duration sintering process. The lattice thermal conductivity was effectively reduced by W substitution, and the ZT value was improved to above 0.5 for both n- and p-type samples.",
        "keywords": "",
        "authors": [
            {
                "name": "Swapnil Ghodke",
                "org": "Nagoya University"
            },
            {
                "name": "Naoya Hiroishi",
                "org": "Nagoya University"
            },
            {
                "name": "Akio Yamamoto",
                "org": "Toyota Technological Institute"
            },
            {
                "name": "Hiroshi Ikuta",
                "org": "Nagoya University"
            },
            {
                "name": "Masaharu Matsunami",
                "org": "Toyota Technological Institute"
            },
            {
                "name": "Tsunehiro Takeuchi",
                "org": "Toyota Technological Institute"
            },
            {
                "name": "Tsunehiro Takeuchi",
                "org": "Toyota Technological Institute"
            }
        ],
        "venue": "Journal of Electronic Materials",
        "year": 2016
    },
    "akuDK63h": {
        "id": "akuDK63h",
        "title": "Carrier concentration dependence of thermoelectric properties of Fe(V1\u2212 x ,Ti x )Sb half-Heusler phase",
        "abstract": "The thermoelectric properties of the FeV1\u2212 x Ti x Sb half-Heusler (HH) phase were studied in the temperature range from 300 to 700 K. All the samples prepared with the compositions of FeV1\u2212 x Ti x Sb (0 \u2264 x \u2264 0.2) possessed a positive Seebeck coefficient, while the sample with x = 0 showed a negative sign. FeV0.80Ti0.20Sb exhibited a large positive Seebeck coefficient exceeding 300 \u00b5V K\u22121 and a low electrical resistivity below 2.00 \u00b1 0.20 m\u03a9 cm at 700 K, leading to a large power factor PF = 4.40 \u00b1 0.50 \u00d7 10\u22123 W m\u22121 K\u22122. The thermal conductivity of FeV1\u2212 x Ti x Sb (x u003e 0) at 300 K decreased to less than half of that of the sample at x = 0, probably because the disordering caused by the Ti substitution enhanced the scattering probability of phonons. The consistency between measured and calculated properties indicates that FeV1\u2212 x Ti x Sb HH is suitable as a new practical thermoelectric material.",
        "keywords": "",
        "authors": [
            {
                "name": "K\u00e9vin Delime-Codrin",
                "org": "Toyota Technological Institute, Nagoya 468-8511, Japan"
            },
            {
                "name": "Tatsuya Yamada",
                "org": "Toyota Technological Institute, Nagoya 468-8511, Japan"
            },
            {
                "name": "Akio Yamamoto",
                "org": "Toyota Technological Institute, Nagoya 468-8511, Japan"
            },
            {
                "name": "Robert Sobota",
                "org": "Toyota Technological Institute, Nagoya 468-8511, Japan"
            },
            {
                "name": "Masaharu Matsunami",
                "org": "Toyota Technological Institute, Nagoya 468-8511, Japan"
            },
            {
                "name": "Tsunehiro Takeuchi",
                "org": "Toyota Technological Institute, Nagoya 468-8511, Japan"
            },
            {
                "name": "Tsunehiro Takeuchi",
                "org": "Toyota Technological Institute, Nagoya 468-8511, Japan"
            },
            {
                "name": "Tsunehiro Takeuchi",
                "org": "Toyota Technological Institute, Nagoya 468-8511, Japan"
            }
        ],
        "venue": "Japanese Journal of Applied Physics",
        "year": 2017
    },
    "6LB2H1yl": {
        "id": "6LB2H1yl",
        "title": "Low-Temperature grown Gallium Arsenide on Silicon by using Migration-Enhanced Epitaxy",
        "abstract": "GaAs were grown by the migration-enhanced epitaxy (MEE) method on vicinal (001) Si substrates oriented 4 \u00b0 off towards [110] at low temperature. Investigations of crystalline and optical properties of the grown GaAs/Si were carried out by the methods of X-ray diffraction (XRD) and low-temperature photoluminescence (PL). The possible cause for tilting in the GaAs grown at low-temperature is discussed.",
        "keywords": "",
        "authors": [
            {
                "name": "Yu-Cian Wang",
                "org": "Toyota Technological Institute, Nagoya, 468-8511, Japan"
            },
            {
                "name": "Akio Yamamoto",
                "org": "Toyota Technological Institute, Nagoya, 468-8511, Japan"
            },
            {
                "name": "Nobuaki Kojima",
                "org": "Toyota Technological Institute, Nagoya, 468-8511, Japan"
            },
            {
                "name": "Yoshio Ohshita",
                "org": "Toyota Technological Institute, Nagoya, 468-8511, Japan"
            },
            {
                "name": "Masafumi Yamaguchi",
                "org": "Toyota Technological Institute, Nagoya, 468-8511, Japan"
            }
        ],
        "venue": "world conference on photovoltaic energy conversion",
        "year": 2018
    },
    "NekVE4HA": {
        "id": "NekVE4HA",
        "title": "Activity of Subcommittee on Follow-up of Unresolved Issues of the Accident from AESJ",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "Atomic Energy Society of Japan",
        "year": 2017
    },
    "h5XySkVM": {
        "id": "h5XySkVM",
        "title": "Development of Three-dimensional Heterogeneous Transport Code GENESIS based on the LEAF method",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "Atomic Energy Society of Japan",
        "year": 2016
    },
    "Glrxt51s": {
        "id": "Glrxt51s",
        "title": "Estimation of even-parity discontinuity factor using MOC",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "Atomic Energy Society of Japan",
        "year": 2018
    },
    "AQ6T6JYW": {
        "id": "AQ6T6JYW",
        "title": "Development of three-dimensional heterogeneous transport code, GENESIS(2)",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "Atomic Energy Society of Japan",
        "year": 2016
    },
    "eUzOWKxV": {
        "id": "eUzOWKxV",
        "title": "Activity of Subcommittee on Follow-up of Unresolved Issues of the Accident and Proposals from AESJ",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "Atomic Energy Society of Japan",
        "year": 2016
    },
    "1IVbnOje": {
        "id": "1IVbnOje",
        "title": "Investigation and evaluation of unresolved issues on Fukushima Daiichi accident",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "Atomic Energy Society of Japan",
        "year": 2018
    },
    "QRabEvkm": {
        "id": "QRabEvkm",
        "title": "V&V Challenges in Reactor Physics Calculations and Future Developments",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "Atomic Energy Society of Japan",
        "year": 2018
    },
    "iGXQl7Tp": {
        "id": "iGXQl7Tp",
        "title": "Classification of Resolved/Unresolved Issues andImplications for Nuclear Safety Research",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "Atomic Energy Society of Japan",
        "year": 2018
    },
    "gNXKzi4j": {
        "id": "gNXKzi4j",
        "title": "(3)Follow up of recommendations in the final report, \"The Fukushima Daiichi Nuclear Accident\"",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            }
        ],
        "venue": "Atomic Energy Society of Japan",
        "year": 2016
    },
    "7zp0x9w2": {
        "id": "7zp0x9w2",
        "title": "Method for measuring tri-axial lumbar motion angles using wearable sheet stretch sensors.",
        "abstract": "The stretch sensors mounted on the back provided reasonable estimates of the lumbar motion angles. The novel motion capture system provided three directional angles without capture space limits. The wearable system possessed great potential to monitor the lower back movement in healthcare workers and helping prevent low back pain.",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": "Department of Community Health Science, Graduate School of Health Science, Kobe University, Kobe, Hyogo, Japan."
            },
            {
                "name": "Hiroyuki Nakamoto",
                "org": "Department of System Science, Graduate School of System Informatics, Kobe University, Kobe, Hyogo, Japan."
            },
            {
                "name": "Tokiya Yamaji",
                "org": "Department of System Science, Graduate School of System Informatics, Kobe University, Kobe, Hyogo, Japan."
            },
            {
                "name": "Hideo Ootaka",
                "org": "Bando Chemical Industries, Ltd., Kobe, Hyogo, Japan."
            },
            {
                "name": "Yusuke Bessho",
                "org": "Bando Chemical Industries, Ltd., Kobe, Hyogo, Japan."
            },
            {
                "name": "Ryo Nakamura",
                "org": "Department of Community Health Science, Graduate School of Health Science, Kobe University, Kobe, Hyogo, Japan."
            },
            {
                "name": "Rei Ono",
                "org": "Department of Community Health Science, Graduate School of Health Science, Kobe University, Kobe, Hyogo, Japan."
            }
        ],
        "venue": "PloS one",
        "year": 2017
    },
    "vCtGjQ6t": {
        "id": "vCtGjQ6t",
        "title": "Wearable Lumbar-Motion Monitoring Device with Stretchable Strain Sensors.",
        "abstract": "Low-back pain is a common affliction. Epidemiological analyses have reported that periodic cycles of lumbar flexion and rotation are major risk factors for low-back pain. To prevent low-back pain, a lumbar-motion monitoring device could help diagnosticians assess patients\u2019 risk for low-back pain. This study proposes such a device that uses lightweight stretchable strain sensors. Six of these strain sensors form a parallel-sensor mechanism that measures rotation angles of lumbar motion in three axes. The parallel-sensor mechanism calculates rotation angles from the lengths of the strain sensors iteratively. Experimental results reveal that the prototype device is effective for lumbar-motion measurement and significantly improves in terms of wearability over comparable devices.",
        "keywords": "",
        "authors": [
            {
                "name": "Hiroyuki Nakamoto",
                "org": "Graduate School of System Informatics, Kobe University, 1-1 Rokkodai-cho, Nada, Kobe 657-8501, Japan"
            },
            {
                "name": "Tokiya Yamaji",
                "org": "Graduate School of System Informatics, Kobe University, 1-1 Rokkodai-cho, Nada, Kobe 657-8501, Japan"
            },
            {
                "name": "Akio Yamamoto",
                "org": "Graduate School of Health Science, Kobe University, 7-10-2 Tomogaoka, Suma, Kobe 654-0142, Japan"
            },
            {
                "name": "Hideo Ootaka",
                "org": "Bando Chemical Industries Ltd, 4-6-6 Minatojima Minamimachi, Chuo, Kobe 650-0047, Japan"
            },
            {
                "name": "Yusuke Bessho",
                "org": "Bando Chemical Industries Ltd, 4-6-6 Minatojima Minamimachi, Chuo, Kobe 650-0047, Japan"
            },
            {
                "name": "Futoshi Kobayashi",
                "org": "Graduate School of System Informatics, Kobe University, 1-1 Rokkodai-cho, Nada, Kobe 657-8501, Japan"
            },
            {
                "name": "Rei Ono",
                "org": ""
            }
        ],
        "venue": "J. Sensors",
        "year": 2018
    },
    "yHUTRdDI": {
        "id": "yHUTRdDI",
        "title": "Development of a Measurement Device Using a Sheet Stretch Sensor for Chest Wall Motion",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": "Kobe University Graduate School of Health Sciences"
            },
            {
                "name": "Hiroyuki Nakamoto",
                "org": "Kobe University Graduate School of System Informatics"
            },
            {
                "name": "Yutaro Oki",
                "org": "Kobe University Graduate School of Health Sciences"
            },
            {
                "name": "Yukari Fujimoto",
                "org": "Kobe University Graduate School of Health Sciences"
            },
            {
                "name": "Yusuke Bessho",
                "org": "BANDO CHEMICAL INDUSTRIES, LTD."
            },
            {
                "name": "Akira Ishikawa",
                "org": "Kobe University Graduate School of Health Sciences"
            }
        ],
        "venue": "The Japanese Journal of Rehabilitation Medicine",
        "year": 2018
    },
    "o8A3Os7U": {
        "id": "o8A3Os7U",
        "title": "Application of a wearable switch to perform a mouse left click for a child with mix type of cerebral palsy: a single case study.",
        "abstract": "The new switch system can be a new option for people with difficulty using standard handheld input devices due to paralysis and involuntary muscle movements. Implications for rehabilitation Cerebral palsy is a major cause of motor dysfunction and spasticity and dyskinesia in the fingers and upper limbs may prevent children with cerebral palsy from using handheld input devices. Wearable devices may be useful for children with cerebral palsy who have limited access to handheld pointing devices. We developed a new wearable switch to control devices using a flexible stretchable sensor. The wearable switch contributed to the improvement of sitting posture and reduction of neck burden during the typing task at the speed equivalent to that using the previous method in a child with mixed type of cerebral palsy exhibiting choreoathetotic movements and bilateral spasticity.",
        "keywords": [
            "Word",
            "adolescents",
            "athetosis",
            "cerebral palsy",
            "disability",
            "spasticity",
            "wearable sensor"
        ],
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": "a Department of Community Health Science, Graduate School of Health Science , Kobe University , Kobe , Japan."
            },
            {
                "name": "Kenji Kihara",
                "org": "b Nikoniko-house Medical Welfare Center , Kobe , Japan."
            },
            {
                "name": "Mariko Yagi",
                "org": "b Nikoniko-house Medical Welfare Center , Kobe , Japan."
            },
            {
                "name": "Yoko Matsumoto",
                "org": "b Nikoniko-house Medical Welfare Center , Kobe , Japan."
            },
            {
                "name": "Shuichi Tsuneishi",
                "org": "c Medical and Welfare Center Kizuna , Kasai , Japan."
            },
            {
                "name": "Hideo Otaka",
                "org": "d Bando Chemical Industries Ltd , Kobe , Japan."
            },
            {
                "name": "Masaya Yonezawa",
                "org": "d Bando Chemical Industries Ltd , Kobe , Japan."
            },
            {
                "name": "Satoshi Takada",
                "org": "a Department of Community Health Science, Graduate School of Health Science , Kobe University , Kobe , Japan."
            }
        ],
        "venue": "Disability and rehabilitation. Assistive technology",
        "year": 2019
    },
    "FaSak8gU": {
        "id": "FaSak8gU",
        "title": "Associated Factors of Psychological Distress among Japanese NICU Nurses in Supporting Bereaved Families Who Have Lost Children.",
        "abstract": "Clarifying the coping methods for psychological distress in supporting bereaved families may be necessary, and nurses need to identify appropriate coping methods. In nursing education, information on psychological distress related to children's deaths and bereavement care should be conveyed from the early stage and nurses must obtain preliminary knowledge. The creation of a bereavement follow-up system is recommended.",
        "keywords": [
            "NICU",
            "bereavement care",
            "children\u2019s deaths",
            "nurses",
            "psychological distress"
        ],
        "authors": [
            {
                "name": "Mari Kitao",
                "org": "Department of Health Sciences, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku Fukuoka 812-8582, Japan."
            },
            {
                "name": "Noriko Setou",
                "org": "Faculty of Nursing and Rehabilitation, Konan Women's University, 6-2-23, Morikita-machi, Higashinada-ku, Kobe, Japan."
            },
            {
                "name": "Akio Yamamoto",
                "org": "Kobe University Graduate School of Health Sciences, 7-10-2 Tomogaoka, Suma-ku Kobe 654-0142, Japan."
            },
            {
                "name": "Satoshi Takada",
                "org": "Kobe University Graduate School of Health Sciences, 7-10-2 Tomogaoka, Suma-ku Kobe 654-0142, Japan."
            }
        ],
        "venue": "The Kobe journal of medical sciences",
        "year": 2018
    },
    "ezq0w2m0": {
        "id": "ezq0w2m0",
        "title": "Impact of fatigue improvement after pulmonary rehabilitation education on the long-term prognosis of patients with COPD",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Yutaro Oki",
                "org": ""
            },
            {
                "name": "Akira Tamaki",
                "org": ""
            },
            {
                "name": "Yukari Fujimoto",
                "org": ""
            },
            {
                "name": "Kanji Yamada",
                "org": ""
            },
            {
                "name": "Yuji Mitani",
                "org": ""
            },
            {
                "name": "Yusuke Iwata",
                "org": ""
            },
            {
                "name": "Takumi Yamaguchi",
                "org": ""
            },
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Hiromi Kaneko",
                "org": ""
            },
            {
                "name": "Mineko Ohira",
                "org": ""
            },
            {
                "name": "Akira Ishikawa",
                "org": ""
            }
        ],
        "venue": "European Respiratory Journal",
        "year": 2018
    },
    "d4vhLygv": {
        "id": "d4vhLygv",
        "title": "Surface Activation of Wood by Corona Treatment and NaOH Soaking for Improved Bond Performance in Plywood",
        "abstract": "In plywood manufacturing, the surface characteristics of veneers play a critical role in achieving appropriate bonding performance. An inactivated wood surface caused by oxidation or migration of wood extractives has been shown to lead to an insufficient bonding quality. In this study, inactivated birch and spruce veneer surfaces were activated with corona and chemical NaOH treatments. The effects of the treatments were determined by contact angle measurements and bond quality tests conducted with Automated Bonding Evaluation System (ABES). In addition, the mechanical properties of the plywood produced from the treated veneers were evaluated. The results showed that the corona treatment remarkably increased the wettability of the veneer surface and bond quality of both the spruce and birch veneers evaluated by ABES. The corona treatment also improved the mechanical properties of the birch plywood, but the spruce plywood properties were not affected as much. Soaking veneers in NaOH improved the wettability, but the bond strength was lower than that of the references.",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": "Aalto University #R##N#School of Chemical Engineering#R##N#Department of Bioproducts and Biosystems#R##N#PO Box 16300#R##N#FI-00076 Aalto"
            },
            {
                "name": "Maija Kym\u00e4l\u00e4inen",
                "org": "Aalto University #R##N#School of Chemical Engineering#R##N#Department of Bioproducts and Biosystems#R##N#PO Box 16300#R##N#FI-00076 Aalto"
            },
            {
                "name": "Timo Lindroos",
                "org": "Aalto University #R##N#School of Chemical Engineering#R##N#Department of Bioproducts and Biosystems#R##N#PO Box 16300#R##N#FI-00076 Aalto"
            },
            {
                "name": "Anti Rohumaa",
                "org": "LaBoMaP, Ecole Nationale Sup\u00e9rieure d'Arts et M\u00e9tiers, Cluny, 71250, France"
            },
            {
                "name": "Kasperi Sokka",
                "org": "Mets\u00e4 Wood (Plywood) Vaneritehtaankatu 1, 44200 Suolahti, Finland"
            },
            {
                "name": "Lauri Rautkari",
                "org": "Department of Bioproducts and Biosystems, School of Chemical Engineering, Aalto University, P.O. Box 16300, 00076 Aalto, Finland"
            }
        ],
        "venue": "Bioresources",
        "year": 2017
    },
    "gaN99U30": {
        "id": "gaN99U30",
        "title": "Surface modification of birch veneer by peroxide bleaching",
        "abstract": "This study examined effects of surface modification with hydrogen peroxide (H2O2) on adhesive bond performance in birch veneer bonded with phenol\u2013formaldehyde resin. The veneer was treated with 5% of H2O2 at 80 \u00b0C in the presence of alkali with the objective of improving adhesive bond performance and reducing the resin demand. The effects of the surface modification were determined by surface color measured with a spectrophotometer, bond performance tests with ABES (automated bonding evaluation system) and surface hydrophobicity with sessile contact angle measurements. Results demonstrated that veneer surface became significantly whiter, which also increased in lightness and decreased in redness and yellowness. ABES test revealed that a remarkable increase in bond performance in the treated veneer and the maximum bond strength with the treatment at 60 min, which was nearly twice as high as reference sample (5.42 \u2192 9.94 N/mm2), was obtained. A notable decrease in contact angle measurements was also observed in the treated veneers (0\u00b0 in 0.5 s). The surface modification of birch veneer with H2O2 + alkali demonstrated greater potential for the improvement of physical characteristics in veneer surface. Other aspects of H2O2 consumption during the treatment are also discussed.",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": "Aalto University"
            },
            {
                "name": "Anti Rohumaa",
                "org": "Aalto University"
            },
            {
                "name": "Mark Hughes",
                "org": "Aalto University"
            },
            {
                "name": "Tapani Vuorinen",
                "org": "Aalto University"
            },
            {
                "name": "Lauri Rautkari",
                "org": "Aalto University"
            }
        ],
        "venue": "Wood Science and Technology",
        "year": 2017
    },
    "5QwgLzWU": {
        "id": "5QwgLzWU",
        "title": "Colorimetric Behavior of Xylem Sap obtained by Mechanical Squeeze from Silver Birch (Betula Pendula) and its Color Control",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Akio Yamamoto",
                "org": ""
            },
            {
                "name": "Anti Rohumaa",
                "org": ""
            },
            {
                "name": "Eero Kontturi",
                "org": ""
            },
            {
                "name": "Mark Hughes",
                "org": ""
            },
            {
                "name": "Pekka Saranp\u00e4\u00e4",
                "org": ""
            },
            {
                "name": "Tapani Vuorinen",
                "org": ""
            }
        ],
        "venue": "Pharmaceutical Biology",
        "year": 2012
    },
    "T2inYNEm": {
        "id": "T2inYNEm",
        "title": "Effect of log soaking and the temperature of peeling on the properties of Rotary-cut birch (Betula pendula Roth) veneer bonded with phenol-formaldehyde adhesive",
        "abstract": "Heating logs prior to peeling positively affects the surface properties of veneer as well as the wood-adhesive bond strength. However, the mechanism behind this increase in strength is not fully understood. The aim of the present study was to separate the influence of soaking temperature and peeling temperature on the physical surface properties and bonding quality. Rotary-cut birch (Betula pendula Roth) logs were soaked at 70 \u00b0C, and half of them were subsequently cooled to 20 \u00b0C prior to peeling. Surface roughness measurements, scanning electron microscopy (SEM), surface integrity testing, color measurements, and wood-adhesive bond testing were conducted with an automated bonding evaluation system. The results showed that logs soaked at 70 \u00b0C and peeled at 20 \u00b0C had roughness, color, integrity, bond strength, and wetting properties more similar to logs soaked and peeled at 70 \u00b0C than those soaked and peeled at 20 \u00b0C. In every test conducted, the effect of soaking temperature was greater than the effect of peeling temperature. High-temperature soaking not only caused softening of the material during the peeling process, but it also caused irreversible changes in the wood material, which affected the veneer surface characteristics and bond strength development.",
        "keywords": "",
        "authors": [
            {
                "name": "Anti Rohumaa",
                "org": "Aalto University"
            },
            {
                "name": "Akio Yamamoto",
                "org": "Aalto University"
            },
            {
                "name": "Christopher G. Hunt",
                "org": "US Forest Service, Forest Products Laboratory"
            },
            {
                "name": "Charles R. Frihart",
                "org": "US Forest Service, Forest Products Laboratory"
            },
            {
                "name": "Mark Hughes",
                "org": "Aalto University"
            },
            {
                "name": "Jaan Kers",
                "org": "Tallinn University of Technology"
            }
        ],
        "venue": "Bioresources",
        "year": 2016
    },
    "6JBnxZjI": {
        "id": "6JBnxZjI",
        "title": "The effect of compression and incision on wood veneer and plywood physical and mechanical properties",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Maija Kym\u00e4l\u00e4inen",
                "org": " Department of Bioproducts and Biosystems, School of Chemical Engineering, Aalto University, Aalto, Finland"
            },
            {
                "name": "Akio Yamamoto",
                "org": " Department of Bioproducts and Biosystems, School of Chemical Engineering, Aalto University, Aalto, Finland"
            },
            {
                "name": "Kasperi Sokka",
                "org": " Mets\u00e4 Wood (Plywood), Suolahti, Finland"
            },
            {
                "name": "Lauri Rautkari",
                "org": " Department of Bioproducts and Biosystems, School of Chemical Engineering, Aalto University, Aalto, Finland"
            }
        ],
        "venue": "Wood Material Science and Engineering",
        "year": 2018
    },
    "TCUORJ90": {
        "authors": [
            {
                "name": "J.Z. Bai",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "O. Bardon",
                "org": "Massachusetts Institute of Technology"
            },
            {
                "name": "R.A. Becker-Szendy",
                "org": "Stanford Linear Accelerator Center"
            },
            {
                "name": "I. Blum",
                "org": "University of Texas at Dallas"
            },
            {
                "name": "A. Breakstone",
                "org": "University of Hawaii"
            },
            {
                "name": "T. Burnett",
                "org": "University of Washington"
            },
            {
                "name": "G.P. Chen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.F. Chen",
                "org": "University of Science and Technology of China"
            },
            {
                "name": "J. Chen",
                "org": "Colorado State University"
            },
            {
                "name": "S.J. Chen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.M. Chen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y. Chen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.B. Chen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.Q. Chen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "B.S. Cheng",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "R.F. Cowan",
                "org": "Massachusetts Institute of Technology"
            },
            {
                "name": "H.C. Cui",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.Z. Cui",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.L. Ding",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.Z. Du",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W. Dunwoodie",
                "org": "Stanford Linear Accelerator Center"
            },
            {
                "name": "X.L. Fan",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Fang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.S. Gao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M.L. Gao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.Q. Gao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W.X. Gao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "P. Gratton",
                "org": "University of Texas at Dallas"
            },
            {
                "name": "J.H. Gu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.D. Gu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W.X. Gu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.F. Gu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.N. Guo",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.W. Han",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y. Han",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "F.A. Harris",
                "org": "University of Hawaii"
            },
            {
                "name": "M. Hatanaka",
                "org": "California Institute of Technology"
            },
            {
                "name": "J. He",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "K.R. He",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M. He",
                "org": "Shandong University"
            },
            {
                "name": "D.G. Hitlin",
                "org": "California Institute of Technology"
            },
            {
                "name": "G.Y. Hu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "T. Hu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.Q. Hu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "D.Q. Huang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.Z. Huang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.M. Izen",
                "org": "University of Texas at Dallas"
            },
            {
                "name": "Q.P. Jia",
                "org": "Colorado State University"
            },
            {
                "name": "C.H. Jiang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.Z. Jiang",
                "org": "Shandong University"
            },
            {
                "name": "S. Jin",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y. Jin",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "L. Jones",
                "org": "California Institute of Technology"
            },
            {
                "name": "S.H. Kang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.J. Ke",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M.H. Kelsey",
                "org": "California Institute of Technology"
            },
            {
                "name": "B.K. Kim",
                "org": "University of Texas at Dallas"
            },
            {
                "name": "Y.F. Lai",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.B. Lan",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "P.F. Lang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "A. Lankford",
                "org": "University of California at Irvine"
            },
            {
                "name": "F. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "P.Q. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Q. Li",
                "org": "Shandong University"
            },
            {
                "name": "R.B. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W.D. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W.G. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.H. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.N. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.S. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.Z. Lin",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.M. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.H. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Q. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "R.G. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.A. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.C. Lou",
                "org": "University of Texas at Dallas"
            },
            {
                "name": "B. Lowery",
                "org": "Kansas State University"
            },
            {
                "name": "F. Lu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.G. Lu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y. Luo",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "A.M. Ma",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "D.H. Ma",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "E.C. Ma",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.M. Ma",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.S. Mao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.P. Mao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "R. Malchow",
                "org": "Colorado State University"
            },
            {
                "name": "M. Mandelkern",
                "org": "University of California at Irvine"
            },
            {
                "name": "H. Marsiske",
                "org": "Stanford Linear Accelerator Center"
            },
            {
                "name": "X.C. Meng",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.L. Ni",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Nie",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.L. Olsen",
                "org": "University of Hawaii"
            },
            {
                "name": "J. Oyang",
                "org": "California Institute of Technology"
            },
            {
                "name": "D. Paluselli",
                "org": "University of Hawaii"
            },
            {
                "name": "L.J. Pan",
                "org": "University of Hawaii"
            },
            {
                "name": "J. Panetta",
                "org": "California Institute of Technology"
            },
            {
                "name": "F. Porter",
                "org": "California Institute of Technology"
            },
            {
                "name": "E. Prabhakar",
                "org": "California Institute of Technology"
            },
            {
                "name": "N.D. Qi",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.K. Que",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Quigley",
                "org": "Massachusetts Institute of Technology"
            },
            {
                "name": "G. Rong",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M. Schernau",
                "org": "University of California at Irvine"
            },
            {
                "name": "B. Schmid",
                "org": "University of California at Irvine"
            },
            {
                "name": "J. Schultz",
                "org": "University of California at Irvine"
            },
            {
                "name": "Y.Y. Shao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "B.W. Shen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "D.L. Shen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H. Shen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.Y. Shen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.Y. Sheng",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.Z. Shi",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.R. Shi",
                "org": "California Institute of Technology"
            },
            {
                "name": "A. Smith",
                "org": "University of California at Irvine"
            },
            {
                "name": "E. Soderstrom",
                "org": "Stanford Linear Accelerator Center"
            },
            {
                "name": "X.F. Song",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Standifird",
                "org": "University of Texas at Dallas"
            },
            {
                "name": "D. Stoker",
                "org": "University of California at Irvine"
            },
            {
                "name": "F. Sun",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.S. Sun",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.J. Sun",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Synodinos",
                "org": "Stanford Linear Accelerator Center"
            },
            {
                "name": "Y.P. Tan",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.Q. Tang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W. Toki",
                "org": "Colorado State University"
            },
            {
                "name": "G.L. Tong",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "E. Torrence",
                "org": "Massachusetts Institute of Technology"
            },
            {
                "name": "F. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "L.S. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "L.Z. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "P. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "P.L. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.M. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "T.J. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.Y. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.L. Wei",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S. Whittaker",
                "org": "Boston University"
            },
            {
                "name": "R. Wilson",
                "org": "Colorado State University"
            },
            {
                "name": "W.J. Wisniewski",
                "org": "Superconducting Supercollider Laboratory"
            },
            {
                "name": "Y.G. Wu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "D.M. Xi",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.M. Xia",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "P.P. Xie",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.X. Xie",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W.J. Xiong",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "D.Z. Xu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M.K. Xu",
                "org": "Hangzhou University"
            },
            {
                "name": "R.S. Xu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.D. Xu",
                "org": "Hangzhou University"
            },
            {
                "name": "Z.Q. Xu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.T. Xue",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "R. Yamamoto",
                "org": "Massachusetts Institute of Technology"
            },
            {
                "name": "J. Yan",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W.G. Yan",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.M. Yang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.Y. Yang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Yang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W. Yang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.B. Yao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M.H. Ye",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.W. Ye",
                "org": "University of Science and Technology of China"
            },
            {
                "name": "S.Z. Ye",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.S. Yu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.X. Yu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.H. Yu",
                "org": "Hangzhou University"
            },
            {
                "name": "Z.Q. Yu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.Z. Yuan",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.Y. Zeng",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "B.Y. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.C. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "D.H. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.L. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.W. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "L.S. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.Q. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.Y. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "D.X. Zhao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.W. Zhao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.W. Zhao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M. Zhao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "P.D. Zhao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W.R. Zhao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.P. Zheng",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "L.S. Zheng",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.P. Zheng",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "G.P. Zhou",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.S. Zhou",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Li Zhou",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.F. Zhou",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.H. Zhou",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.G. Zhu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Q.M. Zhu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.C. Zhu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.S. Zhu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "B.A. Zhuang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "G. Zioulas",
                "org": "University of California at Irvine"
            }
        ],
        "title": "Measurement of the mass of the \u03c4 lepton",
        "keywords": [
            ""
        ],
        "venue": "Physical Review D",
        "year": 1996,
        "id": "TCUORJ90"
    },
    "YULQ0RB8": {
        "authors": [
            {
                "name": "J.Z. Bai",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "O. Bardon",
                "org": "Massachusetts Institute of Technology"
            },
            {
                "name": "I. Blum",
                "org": "University of Texas at Dallas"
            },
            {
                "name": "A. Breakstone",
                "org": "University of Hawaii"
            },
            {
                "name": "T. Burnett",
                "org": "University of Washington"
            },
            {
                "name": "G.P. Chen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.F. Chen",
                "org": "China's University of Science and Technology"
            },
            {
                "name": "J. Chen",
                "org": "Colorado State University"
            },
            {
                "name": "S.M. Chen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y. Chen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.B. Chen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.Q. Chen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "B.S. Cheng",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "R.F. Cowan",
                "org": "Massachusetts Institute of Technology"
            },
            {
                "name": "X.Z. Cui",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.L. Ding",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.Z. Du",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W. Dunwoodie",
                "org": "Stanford Linear Accelerator Center"
            },
            {
                "name": "X.L. Fan",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Fang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M. Fero",
                "org": "Massachusetts Institute of Technology"
            },
            {
                "name": "C.S. Gao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M.L. Gao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.Q. Gao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "P. Gratton",
                "org": "University of Texas at Dallas"
            },
            {
                "name": "J.H. Gu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.D. Gu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W.X. Gu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.F. Gu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.N. Guo",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.W. Han",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y. Han",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "F.A. Harris",
                "org": "University of Hawaii"
            },
            {
                "name": "M. Hatanaka",
                "org": "California Institute of Technology"
            },
            {
                "name": "J. He",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M. He",
                "org": "Shandong University"
            },
            {
                "name": "D.G. Hitlin",
                "org": "California Institute of Technology"
            },
            {
                "name": "G.Y. Hu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "T. Hu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.Q. Hu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "D.Q. Huang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.Z. Huang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.M. Izen",
                "org": "University of Texas at Dallas"
            },
            {
                "name": "Q.P. Jia",
                "org": "Colorado State University"
            },
            {
                "name": "C.H. Jiang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S. Jin",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y. Jin",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "L. Jones",
                "org": "California Institute of Technology"
            },
            {
                "name": "S.H. Kang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.J. Ke",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M.H. Kelsey",
                "org": "California Institute of Technology"
            },
            {
                "name": "B.K. Kim",
                "org": "University of Texas at Dallas"
            },
            {
                "name": "D. Kong",
                "org": "University of Hawaii"
            },
            {
                "name": "Y.F. Lai",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.B. Lan",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "P.F. Lang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "A. Lankford",
                "org": "University of California at Irvine"
            },
            {
                "name": "F. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "P.Q. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Q. Li",
                "org": "Shandong University"
            },
            {
                "name": "R.B. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W.D. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W.G. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.H. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.N. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.Z. Lin",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.M. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.H. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Q. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "R.G. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.A. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.C. Lou",
                "org": "University of Texas at Dallas"
            },
            {
                "name": "B. Lowery",
                "org": "University of Texas at Dallas"
            },
            {
                "name": "J.G. Lu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.Q. Luo",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y. Luo",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "A.M. Ma",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "E.C. Ma",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.M. Ma",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.S. Mao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.P. Mao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "R. Malchow",
                "org": "Colorado State University"
            },
            {
                "name": "M. Mandelkern",
                "org": "University of California at Irvine"
            },
            {
                "name": "X.C. Meng",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.L. Ni",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Nie",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.L. Olsen",
                "org": "University of Hawaii"
            },
            {
                "name": "J. Oyang",
                "org": "California Institute of Technology"
            },
            {
                "name": "D. Paluselli",
                "org": "University of Hawaii"
            },
            {
                "name": "L.J. Pan",
                "org": "University of Hawaii"
            },
            {
                "name": "J. Panetta",
                "org": "California Institute of Technology"
            },
            {
                "name": "F. Porter",
                "org": "California Institute of Technology"
            },
            {
                "name": "E. Prabhakar",
                "org": "California Institute of Technology"
            },
            {
                "name": "N.D. Qi",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.K. Que",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Quigley",
                "org": "Massachusetts Institute of Technology"
            },
            {
                "name": "G. Rong",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M. Schernau",
                "org": "University of California at Irvine"
            },
            {
                "name": "B. Schmid",
                "org": "University of California at Irvine"
            },
            {
                "name": "J. Schultz",
                "org": "University of California at Irvine"
            },
            {
                "name": "Y.Y. Shao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "B.W. Shen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "D.L. Shen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H. Shen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.Y. Shen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.Y. Sheng",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.Z. Shi",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.R. Shi",
                "org": "California Institute of Technology"
            },
            {
                "name": "A. Smith",
                "org": "University of California at Irvine"
            },
            {
                "name": "E. Soderstrom",
                "org": "Stanford Linear Accelerator Center"
            },
            {
                "name": "X.F. Song",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Standifird",
                "org": "University of Texas at Dallas"
            },
            {
                "name": "D. Stoker",
                "org": "University of California at Irvine"
            },
            {
                "name": "F. Sun",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.S. Sun",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.J. Sun",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Synodinos",
                "org": "Stanford Linear Accelerator Center"
            },
            {
                "name": "Y.P. Tan",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.Q. Tang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W. Toki",
                "org": "Colorado State University"
            },
            {
                "name": "G.L. Tong",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "E. Torrence",
                "org": "Massachusetts Institute of Technology"
            },
            {
                "name": "F. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "L.S. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "L.Z. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "P. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "P.L. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.M. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "T.J. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.Y. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.L. Wei",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S. Whittaker",
                "org": "Boston University"
            },
            {
                "name": "R. Wilson",
                "org": "Colorado State University"
            },
            {
                "name": "W.J. Wisniewski",
                "org": "Superconducting Supercollider Laboratory"
            },
            {
                "name": "D.M. Xi",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.M. Xia",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "P.P. Xie",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W.J. Xiong",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "D.Z. Xu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "R.S. Xu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.Q. Xu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.T. Xue",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "R. Yamamoto",
                "org": "Massachusetts Institute of Technology"
            },
            {
                "name": "J. Yan",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W.G. Yan",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.M. Yang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.Y. Yang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Yang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W. Yang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M.H. Ye",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.W. Ye",
                "org": "China's University of Science and Technology"
            },
            {
                "name": "S.Z. Ye",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "K. Young",
                "org": "University of Washington"
            },
            {
                "name": "C.S. Yu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.X. Yu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.Q. Yu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.Z. Yuan",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "B.Y. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.C. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "D.H. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.L. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.W. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "L.S. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.Q. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.Y. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "D.X. Zhao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.W. Zhao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.W. Zhao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M. Zhao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "P.D. Zhao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W.R. Zhao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.P. Zheng",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "L.S. Zheng",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.P. Zheng",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "G.P. Zhou",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.S. Zhou",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "L. Zhou",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.F. Zhou",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.H. Zhou",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Q.M. Zhu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.C. Zhu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.S. Zhu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "B.A. Zhuang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "G. Zioulas",
                "org": "University of California at Irvine"
            }
        ],
        "title": "Search for a vector glueball by a scan of the Jl\u03c8 resonance",
        "keywords": [
            ""
        ],
        "venue": "Physical Review D - Particles, Fields, Gravitation and Cosmology",
        "year": 1996,
        "id": "YULQ0RB8"
    },
    "tAOdgWXB": {
        "authors": [
            {
                "name": "J.Z. Bai",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.G. Bian",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.W. Chai",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "G.P. Chen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.F. Chen",
                "org": "China's University of Science and Technology"
            },
            {
                "name": "J.C. Chen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.M. Chen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y. Chen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.B. Chen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.Q. Chen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "B.S. Cheng",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.D. Cheng",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.Z. Cui",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.L. Ding",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W.Y. Ding",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.Z. Du",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.L. Fan",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Fang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.S. Gao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M.L. Gao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.Q. Gao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.H. Gu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.D. Gu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W.X. Gu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.F. Gu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.N. Guo",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.W. Han",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y. Han",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. He",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.T. He",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M. He",
                "org": "Shandong University"
            },
            {
                "name": "G.Y. Hu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.L. Hu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Q.H. Hu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "T. Hu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.Q. Hu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.P. Huang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.Z. Huang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.H. Jiang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S. Jin",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y. Jin",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.H. Kang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.J. Ke",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.F. Lai",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.B. Lan",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "P.F. Lang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "P.Q. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Q. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "R.B. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W.D. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W.G. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.H. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.N. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.Z. Lin",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.M. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.H. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Q. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "R.G. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.A. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "F. Lu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.G. Lu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.Y. Lu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "L.C. Lu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.Q. Luo",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y. Luo",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "A.M. Ma",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "E.C. Ma",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.M. Ma",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.S. Mao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.P. Mao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.C. Meng",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.L. Ni",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Nie",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "N.D. Qi",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.F. Qiu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.H. Qu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.K. Que",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "G. Rong",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.Y. Shao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "B.W. Shen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "D.L. Shen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H. Shen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.Y. Shen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.Y. Sheng",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.Z. Shi",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.F. Song",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "F. Sun",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.S. Sun",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.J. Sun",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.P. Tan",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.Q. Tang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "G.L. Tong",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "F. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.F. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "L.S. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "L.Z. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Men Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "P. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "P.L. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.M. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "T.J. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.Y. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.L. Wei",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.G. Wu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "D.M. Xi",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.M. Xia",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "P.P. Xie",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.G. Xie",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W.J. Xiong",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "G.F. Xu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "R.S. Xu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.Q. Xu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.T. Xue",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Yan",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W.G. Yan",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.M. Yang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.Y. Yang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Yang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.F. Yang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M.H. Ye",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.W. Ye",
                "org": "China's University of Science and Technology"
            },
            {
                "name": "S.Z. Ye",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "K. Yi",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.S. Yu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.X. Yu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.Q. Yu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.T. Yu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.Z. Yuan",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "B.Y. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.C. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "D.H. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H. de Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.L. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.W. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "L. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "L.S. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Q.J. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.Q. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.Y. Zhang",
                "org": "Shandong University"
            },
            {
                "name": "Y. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.Y. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "D.X. Zhao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.W. Zhao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.W. Zhao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M. Zhao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W.H. Zhao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W.R. Zhao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.P. Zheng",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "L.S. Zheng",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.P. Zheng",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "G.P. Zhou",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.S. Zhou",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "L. Zhou",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.H. Zhou",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Q.M. Zhu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.C. Zhu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.S. Zhu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "B.A. Zhuang",
                "org": ""
            }
        ],
        "title": "Structure analysis of the \u222b",
        "keywords": [
            ""
        ],
        "venue": "Physical Review Letters",
        "year": 1996,
        "id": "tAOdgWXB"
    },
    "kfvarzFX": {
        "authors": [
            {
                "name": "J.Z. Bai",
                "org": ""
            },
            {
                "name": "O. Bardon",
                "org": ""
            },
            {
                "name": "I. Blum",
                "org": ""
            },
            {
                "name": "A. Breakstone",
                "org": ""
            },
            {
                "name": "T. Burnett",
                "org": ""
            },
            {
                "name": "G. Chen",
                "org": ""
            },
            {
                "name": "G.P. Chen",
                "org": ""
            },
            {
                "name": "H.F. Chen",
                "org": ""
            },
            {
                "name": "J. Chen",
                "org": ""
            },
            {
                "name": "S.M. Chen",
                "org": ""
            },
            {
                "name": "Y. Chen",
                "org": ""
            },
            {
                "name": "Y.B. Chen",
                "org": ""
            },
            {
                "name": "Y.Q. Chen",
                "org": ""
            },
            {
                "name": "B.S. Cheng",
                "org": ""
            },
            {
                "name": "R.F. Cowan",
                "org": ""
            },
            {
                "name": "X.Z. Cui",
                "org": ""
            },
            {
                "name": "H.L. Ding",
                "org": ""
            },
            {
                "name": "Z.Z. Du",
                "org": ""
            },
            {
                "name": "W. Dunwoodie",
                "org": ""
            },
            {
                "name": "X.L. Fan",
                "org": ""
            },
            {
                "name": "J. Fang",
                "org": ""
            },
            {
                "name": "M. Fero",
                "org": ""
            },
            {
                "name": "C.S. Gao",
                "org": ""
            },
            {
                "name": "M.L. Gao",
                "org": ""
            },
            {
                "name": "S.Q. Gao",
                "org": ""
            },
            {
                "name": "P. Gratton",
                "org": ""
            },
            {
                "name": "J.H. Gu",
                "org": ""
            },
            {
                "name": "S.D. Gu",
                "org": ""
            },
            {
                "name": "W.X. Gu",
                "org": ""
            },
            {
                "name": "Y.F. Gu",
                "org": ""
            },
            {
                "name": "Y.N. Guo",
                "org": ""
            },
            {
                "name": "S.W. Han",
                "org": ""
            },
            {
                "name": "Y. Han",
                "org": ""
            },
            {
                "name": "F.A. Harris",
                "org": ""
            },
            {
                "name": "M. Hatanaka",
                "org": ""
            },
            {
                "name": "J. He",
                "org": ""
            },
            {
                "name": "M. He",
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            },
            {
                "name": "D.G. Hitlin",
                "org": ""
            },
            {
                "name": "G.Y. Hu",
                "org": ""
            },
            {
                "name": "T. Hu",
                "org": ""
            },
            {
                "name": "X.Q. Hu",
                "org": ""
            },
            {
                "name": "Y. Hu",
                "org": ""
            },
            {
                "name": "D.Q. Huang",
                "org": ""
            },
            {
                "name": "Y.Z. Huang",
                "org": ""
            },
            {
                "name": "J.M. Izen",
                "org": ""
            },
            {
                "name": "Q.P. Jia",
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            },
            {
                "name": "C.H. Jiang",
                "org": ""
            },
            {
                "name": "S. Jin",
                "org": ""
            },
            {
                "name": "Y. Jin",
                "org": ""
            },
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                "org": ""
            },
            {
                "name": "S.H. Kang",
                "org": ""
            },
            {
                "name": "Z.J. Ke",
                "org": ""
            },
            {
                "name": "M.H. Kelsey",
                "org": ""
            },
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                "org": ""
            },
            {
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                "org": ""
            },
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                "org": ""
            },
            {
                "name": "H.B. Lan",
                "org": ""
            },
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                "org": ""
            },
            {
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                "org": ""
            },
            {
                "name": "F. Li",
                "org": ""
            },
            {
                "name": "J. Li",
                "org": ""
            },
            {
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            },
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            },
            {
                "name": "R.B. Li",
                "org": ""
            },
            {
                "name": "W. Li",
                "org": ""
            },
            {
                "name": "W.D. Li",
                "org": ""
            },
            {
                "name": "W.G. Li",
                "org": ""
            },
            {
                "name": "X.H. Li",
                "org": ""
            },
            {
                "name": "X.N. Li",
                "org": ""
            },
            {
                "name": "S.Z. Lin",
                "org": ""
            },
            {
                "name": "H.M. Liu",
                "org": ""
            },
            {
                "name": "J. Liu",
                "org": ""
            },
            {
                "name": "J.H. Liu",
                "org": ""
            },
            {
                "name": "Q. Liu",
                "org": ""
            },
            {
                "name": "R.G. Liu",
                "org": ""
            },
            {
                "name": "Y. Liu",
                "org": ""
            },
            {
                "name": "Z.A. Liu",
                "org": ""
            },
            {
                "name": "X.C. Lou",
                "org": ""
            },
            {
                "name": "B. Lowery",
                "org": ""
            },
            {
                "name": "J.G. Lu",
                "org": ""
            },
            {
                "name": "S.Q. Luo",
                "org": ""
            },
            {
                "name": "Y. Luo",
                "org": ""
            },
            {
                "name": "A.M. Ma",
                "org": ""
            },
            {
                "name": "E.C. Ma",
                "org": ""
            },
            {
                "name": "J.M. Ma",
                "org": ""
            },
            {
                "name": "H.S. Mao",
                "org": ""
            },
            {
                "name": "Z.P. Mao",
                "org": ""
            },
            {
                "name": "R. Malchow",
                "org": ""
            },
            {
                "name": "M. Mandelkern",
                "org": ""
            },
            {
                "name": "X.C. Meng",
                "org": ""
            },
            {
                "name": "H.L. Ni",
                "org": ""
            },
            {
                "name": "J. Nie",
                "org": ""
            },
            {
                "name": "S.L. Olsen",
                "org": ""
            },
            {
                "name": "J. Oyang",
                "org": ""
            },
            {
                "name": "D. Paluselli",
                "org": ""
            },
            {
                "name": "L.J. Pan",
                "org": ""
            },
            {
                "name": "J. Panetta",
                "org": ""
            },
            {
                "name": "F. Porter",
                "org": ""
            },
            {
                "name": "E. Prabhakar",
                "org": ""
            }
        ],
        "title": "Study of \u03c8(2S) Decays into \u03c1\u03c0 and KK *",
        "keywords": [
            "\u03c8 (2S)",
            "Anomalous suppression",
            "Branching fraction",
            "Pseudoscalar",
            "Vector"
        ],
        "venue": "Kao Neng Wu Li Yu Ho Wu Li/High Energy Physics and Nuclear Physics",
        "year": 1996,
        "id": "kfvarzFX"
    },
    "5ZVoQfxq": {
        "authors": [
            {
                "name": "J.Z. Bai",
                "org": ""
            },
            {
                "name": "O. Bardon",
                "org": ""
            },
            {
                "name": "I. Blum",
                "org": ""
            },
            {
                "name": "A. Breakstone",
                "org": ""
            },
            {
                "name": "T. Burnett",
                "org": ""
            },
            {
                "name": "G.P. Chen",
                "org": ""
            },
            {
                "name": "H.F. Chen",
                "org": ""
            },
            {
                "name": "J. Chen",
                "org": ""
            },
            {
                "name": "S.M. Chen",
                "org": ""
            },
            {
                "name": "Y. Chen",
                "org": ""
            },
            {
                "name": "Y.B. Chen",
                "org": ""
            },
            {
                "name": "Y.Q. Chen",
                "org": ""
            },
            {
                "name": "B.S. Cheng",
                "org": ""
            },
            {
                "name": "R.F. Cowan",
                "org": ""
            },
            {
                "name": "X.Z. Cui",
                "org": ""
            },
            {
                "name": "H.L. Ding",
                "org": ""
            },
            {
                "name": "Z.Z. Du",
                "org": ""
            },
            {
                "name": "W. Dunwoodie",
                "org": ""
            },
            {
                "name": "X.L. Fan",
                "org": ""
            },
            {
                "name": "J. Fang",
                "org": ""
            },
            {
                "name": "M. Fero",
                "org": ""
            },
            {
                "name": "C.S. Gao",
                "org": ""
            },
            {
                "name": "M.L. Gao",
                "org": ""
            },
            {
                "name": "S.Q. Gao",
                "org": ""
            },
            {
                "name": "P. Gratton",
                "org": ""
            },
            {
                "name": "J.H. Gu",
                "org": ""
            },
            {
                "name": "S.D. Gu",
                "org": ""
            },
            {
                "name": "W.X. Gu",
                "org": ""
            },
            {
                "name": "Y.F. Gu",
                "org": ""
            },
            {
                "name": "Y.N. Guo",
                "org": ""
            },
            {
                "name": "S.W. Han",
                "org": ""
            },
            {
                "name": "Y. Han",
                "org": ""
            },
            {
                "name": "F.A. Harris",
                "org": ""
            },
            {
                "name": "M. Hatanaka",
                "org": ""
            },
            {
                "name": "J. He",
                "org": ""
            },
            {
                "name": "M. He",
                "org": ""
            },
            {
                "name": "D.G. Hitlin",
                "org": ""
            },
            {
                "name": "G.Y. Hu",
                "org": ""
            },
            {
                "name": "T. Hu",
                "org": ""
            },
            {
                "name": "X.Q. Hu",
                "org": ""
            },
            {
                "name": "D.Q. Huang",
                "org": ""
            },
            {
                "name": "Y.Z. Huang",
                "org": ""
            },
            {
                "name": "J.M. Izen",
                "org": ""
            },
            {
                "name": "Q.P. Jia",
                "org": ""
            },
            {
                "name": "C.H. Jiang",
                "org": ""
            },
            {
                "name": "S. Jin",
                "org": ""
            },
            {
                "name": "Y. Jin",
                "org": ""
            },
            {
                "name": "L. Jones",
                "org": ""
            },
            {
                "name": "S.H. Kang",
                "org": ""
            },
            {
                "name": "Z.J. Ke",
                "org": ""
            },
            {
                "name": "M.H. Kelsey",
                "org": ""
            },
            {
                "name": "B.K. Kim",
                "org": ""
            },
            {
                "name": "D. Kong",
                "org": ""
            },
            {
                "name": "Y.F. Lai",
                "org": ""
            },
            {
                "name": "H.B. Lan",
                "org": ""
            },
            {
                "name": "P.F. Lang",
                "org": ""
            },
            {
                "name": "A. Lankford",
                "org": ""
            },
            {
                "name": "F. Li",
                "org": ""
            },
            {
                "name": "J. Li",
                "org": ""
            },
            {
                "name": "P.Q. Li",
                "org": ""
            },
            {
                "name": "Q. Li",
                "org": ""
            },
            {
                "name": "R.B. Li",
                "org": ""
            },
            {
                "name": "W. Li",
                "org": ""
            },
            {
                "name": "W.D. Li",
                "org": ""
            },
            {
                "name": "W.G. Li",
                "org": ""
            },
            {
                "name": "X.H. Li",
                "org": ""
            },
            {
                "name": "X.N. Li",
                "org": ""
            },
            {
                "name": "S.Z. Lin",
                "org": ""
            },
            {
                "name": "H.M. Liu",
                "org": ""
            },
            {
                "name": "J. Liu",
                "org": ""
            },
            {
                "name": "J.H. Liu",
                "org": ""
            },
            {
                "name": "Q. Liu",
                "org": ""
            },
            {
                "name": "R.G. Liu",
                "org": ""
            },
            {
                "name": "Y. Liu",
                "org": ""
            },
            {
                "name": "Z.A. Liu",
                "org": ""
            },
            {
                "name": "X.C. Lou",
                "org": ""
            },
            {
                "name": "B. Lowery",
                "org": ""
            },
            {
                "name": "J.G. Lu",
                "org": ""
            },
            {
                "name": "J.Y. Lu",
                "org": ""
            },
            {
                "name": "S.Q. Luo",
                "org": ""
            },
            {
                "name": "Y. Luo",
                "org": ""
            },
            {
                "name": "A.M. Ma",
                "org": ""
            },
            {
                "name": "E.C. Ma",
                "org": ""
            },
            {
                "name": "J.M. Ma",
                "org": ""
            },
            {
                "name": "H.S. Mao",
                "org": ""
            },
            {
                "name": "Z.P. Mao",
                "org": ""
            },
            {
                "name": "R. Malchow",
                "org": ""
            },
            {
                "name": "M. Mandelkern",
                "org": ""
            },
            {
                "name": "X.C. Meng",
                "org": ""
            },
            {
                "name": "H.L. Ni",
                "org": ""
            },
            {
                "name": "J. Nie",
                "org": ""
            },
            {
                "name": "S.L. Olsen",
                "org": ""
            },
            {
                "name": "J. Oyang",
                "org": ""
            },
            {
                "name": "D. Paluselli",
                "org": ""
            },
            {
                "name": "L.J. Pan",
                "org": ""
            },
            {
                "name": "J. Panetta",
                "org": ""
            },
            {
                "name": "F. Porter",
                "org": ""
            },
            {
                "name": "E. Prabhakar",
                "org": ""
            },
            {
                "name": "N.D. Qi",
                "org": ""
            }
        ],
        "title": "Measurement of D",
        "keywords": [
            "Beijing spectrometer",
            "Branching ratio",
            "Ds",
            "Decay constant",
            "Leptonic decay"
        ],
        "venue": "Kao Neng Wu Li Yu Ho Wu Li/High Energy Physics and Nuclear Physics",
        "year": 1996,
        "id": "5ZVoQfxq"
    },
    "AADoLhZH": {
        "authors": [
            {
                "name": "J.Z. Bai",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "G.P. Chen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.F. Chen",
                "org": "China's University of Science and Technology"
            },
            {
                "name": "S.J. Chen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.M. Chen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y. Chen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.B. Chen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.Q. Chen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "B.S. Cheng",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.Z. Cui",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.L. Ding",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W.Y. Ding",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.Z. Du",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.L. Fan",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Fang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.S. Gao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M.L. Gao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.Q. Gao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.H. Gu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.D. Gu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W.X. Gu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.F. Gu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.N. Guo",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.W. Han",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y. Han",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. He",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M. He",
                "org": "Shandong University"
            },
            {
                "name": "G.Y. Hu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "T. Hu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.Q. Hu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "D.Q. Huang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "T. Huang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.Z. Huang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.H. Jiang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S. Jin",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y. Jin",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.H. Kang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.J. Ke",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.F. Lai",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.B. Lan",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "P.F. Lang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "F. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "P.Q. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Q. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "R.B. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W.D. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W.G. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.H. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.N. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.Z. Lin",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.M. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.H. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Q. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "R.G. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.A. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.G. Lu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.Y. Lu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.Q. Luo",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y. Luo",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "A.M. Ma",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "E.C. Ma",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.M. Ma",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.S. Mao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.P. Mao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.C. Meng",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.L. Ni",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Nie",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "N.D. Qi",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.K. Que",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "G. Rong",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.Y. Shao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "B.W. Shen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "D.L. Shen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H. Shen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.Y. Shen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.Y. Sheng",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.Z. Shi",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.F. Song",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "F. Sun",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.S. Sun",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.J. Sun",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.P. Tan",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.Q. Tang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "G.L. Tong",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "F. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "L.S. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "L.Z. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "P. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "P.L. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.M. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "T.J. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.Y. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.L. Wei",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "D.M. Xi",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.M. Xia",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "P.P. Xie",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.G. Xie",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W.J. Xiong",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "D.Z. Xu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "R.S. Xu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.Q. Xu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.T. Xue",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Yan",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W.G. Yan",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.M. Yang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.Y. Yang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Yang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W. Yang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M.H. Ye",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.W. Ye",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.Z. Ye",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.S. Yu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.X. Yu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.Q. Yu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.T. Yu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.Z. Yuan",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "B.Y. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.C. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "D.H. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.L. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.W. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "L. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "L.S. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.Q. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.Y. Zhang",
                "org": "Shandong University"
            },
            {
                "name": "Y. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.Y. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "D.X. Zhao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.W. Zhao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.W. Zhao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M. Zhao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "P.D. Zhao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W.R. Zhao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.P. Zheng",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "L.S. Zheng",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.P. Zheng",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "G.P. Zhou",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.S. Zhou",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "L. Zhou",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.F. Zhou",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.H. Zhou",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Q.M. Zhu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.C. Zhu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.S. Zhu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "B.A. Zhuang",
                "org": "Institute of High Energy Physics"
            }
        ],
        "title": "Studies of \u03be (2230) in J/\u03c8 radiative decays",
        "keywords": [
            ""
        ],
        "venue": "Physical Review Letters",
        "year": 1996,
        "id": "AADoLhZH"
    },
    "oMPEyD9E": {
        "authors": [
            {
                "name": "J.Z. Bai",
                "org": ""
            },
            {
                "name": "O. Bardon",
                "org": ""
            },
            {
                "name": "J.G. Bian",
                "org": ""
            },
            {
                "name": "I. Blum",
                "org": ""
            },
            {
                "name": "A. Breakstone",
                "org": ""
            },
            {
                "name": "T. Burnett",
                "org": ""
            },
            {
                "name": "Z.W. Chai",
                "org": ""
            },
            {
                "name": "G.P. Chen",
                "org": ""
            },
            {
                "name": "H.F. Chen",
                "org": ""
            },
            {
                "name": "J. Chen",
                "org": ""
            },
            {
                "name": "J.C. Chen",
                "org": ""
            },
            {
                "name": "S.M. Chen",
                "org": ""
            },
            {
                "name": "Y. Chen",
                "org": ""
            },
            {
                "name": "Y.B. Chen",
                "org": ""
            },
            {
                "name": "Y.Q. Chen",
                "org": ""
            },
            {
                "name": "B.S. Cheng",
                "org": ""
            },
            {
                "name": "R.F. Cowan",
                "org": ""
            },
            {
                "name": "X.Z. Cui",
                "org": ""
            },
            {
                "name": "H.L. Ding",
                "org": ""
            },
            {
                "name": "Z.Z. Du",
                "org": ""
            },
            {
                "name": "W. Dunwoodie",
                "org": ""
            },
            {
                "name": "X.L. Fan",
                "org": ""
            },
            {
                "name": "J. Fang",
                "org": ""
            },
            {
                "name": "M. Fero",
                "org": ""
            },
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            }
        ],
        "title": "Measurement of the branching fraction of D",
        "keywords": [
            ""
        ],
        "venue": "Physical Review D - Particles, Fields, Gravitation and Cosmology",
        "year": 1997,
        "id": "oMPEyD9E"
    },
    "BPtCOPS7": {
        "authors": [
            {
                "name": "J.Z. Bai",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "G.P. Chen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.F. Chen",
                "org": "Department of Modern Physics"
            },
            {
                "name": "S.M. Chen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y. Chen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.B. Chen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.Q. Chen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "B.S. Cheng",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.Z. Cui",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.L. Ding",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W.Y. Ding",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.Z. Du",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.L. Fan",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Fang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.S. Gao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M.L. Gao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.Q. Gao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.H. Gu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.D. Gu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W.X. Gu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.F. Gu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.N. Guo",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.W. Han",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y. Han",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.T. He",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. He",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M. He",
                "org": "Department of Physics"
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            {
                "name": "G.Y. Hu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.L. Hu",
                "org": "Institute of High Energy Physics"
            },
            {
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                "org": "Institute of High Energy Physics"
            },
            {
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                "org": "Institute of High Energy Physics"
            },
            {
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                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.Z. Huang",
                "org": "Institute of High Energy Physics"
            },
            {
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                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S. Jin",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y. Jin",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.H. Kang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.J. Ke",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.F. Lai",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.B. Lan",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "P.F. Lang",
                "org": "Institute of High Energy Physics"
            },
            {
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                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "P.Q. Li",
                "org": "Institute of High Energy Physics"
            },
            {
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                "org": "Institute of High Energy Physics"
            },
            {
                "name": "R.B. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W.D. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W.G. Li",
                "org": "Institute of High Energy Physics"
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            {
                "name": "X.H. Li",
                "org": "Institute of High Energy Physics"
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            {
                "name": "X.N. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.Z. Lin",
                "org": "Institute of High Energy Physics"
            },
            {
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                "org": "Institute of High Energy Physics"
            },
            {
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                "org": "Institute of High Energy Physics"
            },
            {
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                "org": "Institute of High Energy Physics"
            },
            {
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                "org": "Institute of High Energy Physics"
            },
            {
                "name": "R.G. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.A. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.G. Lu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.Y. Lu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.Q. Luo",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y. Luo",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "A.M. Ma",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "E.C. Ma",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.M. Ma",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.S. Mao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.P. Mao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.C. Meng",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.L. Ni",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Nie",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "N.D. Qi",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.K. Que",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "G. Rong",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.Y. Shao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "B.W. Shen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "D.L. Shen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H. Shen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.Y. Shen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.Y. Sheng",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.Z. Shi",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.F. Song",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "F. Sun",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.S. Sun",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.J. Sun",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.P. Tan",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.Q. Tang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "G.L. Tong",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "F. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "L.S. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "L.Z. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "P. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "P.L. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.M. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "T.J. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.Y. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.L. Wei",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "D.M. Xi",
                "org": "Institute of High Energy Physics"
            }
        ],
        "title": "Structure Analysis of the \u03b9 / \u03b7(1440): BES Collaboration",
        "keywords": [
            "Covariant matrix",
            "Decay amplitude",
            "Moment",
            "Resonance"
        ],
        "venue": "Kao Neng Wu Li Yu Ho Wu Li/High Energy Physics and Nuclear Physics",
        "year": 1997,
        "id": "BPtCOPS7"
    },
    "rRXoy4wQ": {
        "authors": [
            {
                "name": "J.Z. Bai",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "O. Bardon",
                "org": "Northeastern University"
            },
            {
                "name": "I. Blum",
                "org": "University of Texas at Dallas"
            },
            {
                "name": "A. Breakstone",
                "org": "University of Hawaii"
            },
            {
                "name": "T. Burnett",
                "org": "University of Washington"
            },
            {
                "name": "G.P. Chen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.F. Chen",
                "org": "China's University of Science and Technology"
            },
            {
                "name": "J. Chen",
                "org": "Colorado State University"
            },
            {
                "name": "S.J. Chen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.M. Chen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y. Chen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.B. Chen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.Q. Chen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "B.S. Cheng",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "R.F. Cowan",
                "org": "Massachusetts Institute of Technology"
            },
            {
                "name": "X.Z. Cui",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.L. Ding",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.Z. Du",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W. Dunwoodie",
                "org": "Stanford Linear Accelerator Center"
            },
            {
                "name": "X.L. Fan",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Fang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.S. Gao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M.L. Gao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.Q. Gao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "P. Gratton",
                "org": "University of Texas at Dallas"
            },
            {
                "name": "J.H. Gu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.D. Gu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W.X. Gu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.F. Gu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.N. Guo",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.W. Han",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y. Han",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "F.A. Harris",
                "org": "University of Hawaii"
            },
            {
                "name": "J. He",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M. He",
                "org": "Shandong University"
            },
            {
                "name": "D.G. Hitlin",
                "org": "California Institute of Technology"
            },
            {
                "name": "G.Y. Hu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "T. Hu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.Q. Hu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "D.Q. Huang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.Z. Huang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.M. Izen",
                "org": "University of Texas at Dallas"
            },
            {
                "name": "C.H. Jiang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S. Jin",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y. Jin",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "L. Jones",
                "org": "California Institute of Technology"
            },
            {
                "name": "S.H. Kang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.J. Ke",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M.H. Kelsey",
                "org": "California Institute of Technology"
            },
            {
                "name": "B.K. Kim",
                "org": "University of Texas at Dallas"
            },
            {
                "name": "D. Kong",
                "org": "University of Hawaii"
            },
            {
                "name": "Y.F. Lai",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.B. Lan",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "P.F. Lang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "A. Lankford",
                "org": "University of California at Irvine"
            },
            {
                "name": "F. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "P.Q. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Q. Li",
                "org": "Shandong University"
            },
            {
                "name": "R.B. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W.D. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W.G. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.H. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.N. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.Z. Lin",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.M. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.H. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Q. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "R.G. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.A. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.C. Lou",
                "org": "University of Texas at Dallas"
            },
            {
                "name": "B. Lowery",
                "org": "University of Texas at Dallas"
            },
            {
                "name": "J.G. Lu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.Y. Lu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S. Luo",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y. Luo",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "A.M. Ma",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "E.C. Ma",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.M. Ma",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "R. Malchow",
                "org": "Colorado State University"
            },
            {
                "name": "M. Mandelkern",
                "org": "University of California at Irvine"
            },
            {
                "name": "H.S. Mao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.P. Mao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.C. Meng",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.L. Ni",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Nie",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.L. Olsen",
                "org": "University of Hawaii"
            },
            {
                "name": "J. Oyang",
                "org": "California Institute of Technology"
            },
            {
                "name": "D. Paluselli",
                "org": "University of Hawaii"
            },
            {
                "name": "L.J. Pan",
                "org": "University of Hawaii"
            },
            {
                "name": "J. Panetta",
                "org": "California Institute of Technology"
            },
            {
                "name": "F. Porter",
                "org": "California Institute of Technology"
            },
            {
                "name": "E. Prabhakar",
                "org": "California Institute of Technology"
            },
            {
                "name": "N.D. Qi",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.K. Que",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "G. Rong",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M. Schernau",
                "org": "University of California at Irvine"
            },
            {
                "name": "B. Schmid",
                "org": "University of California at Irvine"
            },
            {
                "name": "J. Schultz",
                "org": "University of California at Irvine"
            },
            {
                "name": "Y.Y. Shao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "D.L. Shen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H. Shen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.Y. Shen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.Y. Sheng",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.Z. Shi",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "E. Soderstrom",
                "org": "Stanford Linear Accelerator Center"
            },
            {
                "name": "X.F. Song",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Standifird",
                "org": "University of Texas at Dallas"
            },
            {
                "name": "D. Stoker",
                "org": "University of California at Irvine"
            },
            {
                "name": "F. Sun",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.S. Sun",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.J. Sun",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Synodinos",
                "org": "Stanford Linear Accelerator Center"
            },
            {
                "name": "Y.P. Tan",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.Q. Tang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W. Toki",
                "org": "Colorado State University"
            },
            {
                "name": "G.L. Tong",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "F. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "L.S. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "L.Z. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "P. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "P.L. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.M. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "T.J. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.Y. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M. Weaver",
                "org": "California Institute of Technology"
            },
            {
                "name": "C.L. Wei",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W.J. Wisniewski",
                "org": "Stanford Linear Accelerator Center"
            },
            {
                "name": "D.M. Xi",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.M. Xia",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "P.P. Xie",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "D.Z. Xu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "R.S. Xu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.Q. Xu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.T. Xue",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Yan",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W.G. Yan",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.M. Yang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.Y. Yang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H. Yang",
                "org": "University of Texas at Dallas"
            },
            {
                "name": "W. Yang",
                "org": "Colorado State University"
            },
            {
                "name": "M.H. Ye",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.Z. Ye",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "K. Young",
                "org": "University of Washington"
            },
            {
                "name": "C.S. Yu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.X. Yu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.Q. Yu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.Z. Yuan",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "B.Y. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.C. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "D.H. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.L. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.W. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "L.S. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.Q. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.Y. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "D.X. Zhao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.W. Zhao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M. Zhao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W.R. Zhao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.P. Zheng",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "L.S. Zheng",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.P. Zheng",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "G.P. Zhou",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.S. Zhou",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "L. Zhou",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.F. Zhou",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.H. Zhou",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Q.M. Zhu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.C. Zhu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.S. Zhu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "B.A. Zhuang",
                "org": "Institute of High Energy Physics"
            }
        ],
        "title": "Direct measurement of B(D",
        "keywords": [
            ""
        ],
        "venue": "Physical Review D - Particles, Fields, Gravitation and Cosmology",
        "year": 1998,
        "id": "rRXoy4wQ"
    },
    "ay0DSoXT": {
        "authors": [
            {
                "name": "J.Z. Bai",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "O. Bardon",
                "org": "Massachusetts Institute of Technology"
            },
            {
                "name": "I. Blum",
                "org": "University of Texas at Dallas"
            },
            {
                "name": "A. Breakstone",
                "org": "University of Hawai'i"
            },
            {
                "name": "T. Burnett",
                "org": "University of Washington"
            },
            {
                "name": "G.P. Chen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.F. Chen",
                "org": "China's University of Science and Technology"
            },
            {
                "name": "J. Chen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.J. Chen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.M. Chen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y. Chen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.B. Chen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.Q. Chen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "B.S. Cheng",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "R.F. Cowan",
                "org": "Massachusetts Institute of Technology"
            },
            {
                "name": "X.Z. Cui",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.L. Ding",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.Z. Du",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W. Dunwoodie",
                "org": "Stanford Linear Accelerator Center"
            },
            {
                "name": "X.L. Fan",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Fang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M. Fero",
                "org": "Massachusetts Institute of Technology"
            },
            {
                "name": "C.S. Gao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M.L. Gao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.Q. Gao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "P. Gratton",
                "org": "University of Texas at Dallas"
            },
            {
                "name": "J.H. Gu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.D. Gu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W.X. Gu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.F. Gu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.N. Guo",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.W. Han",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y. Han",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "F.A. Harris",
                "org": "University of Hawai'i"
            },
            {
                "name": "M. Hatanaka",
                "org": "California Institute of Technology"
            },
            {
                "name": "J. He",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M. He",
                "org": "Shandong University"
            },
            {
                "name": "D.G. Hitlin",
                "org": "California Institute of Technology"
            },
            {
                "name": "G.Y. Hu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "T. Hu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.Q. Hu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "D.Q. Huang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.Z. Huang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.M. Izen",
                "org": "University of Texas at Dallas"
            },
            {
                "name": "Q.P. Jia",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.H. Jiang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S. Jin",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y. Jin",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "L. Jones",
                "org": "California Institute of Technology"
            },
            {
                "name": "S.H. Kang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.J. Ke",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M.H. Kelsey",
                "org": "California Institute of Technology"
            },
            {
                "name": "B.K. Kim",
                "org": "University of Texas at Dallas"
            },
            {
                "name": "D. Kong",
                "org": "University of Hawai'i"
            },
            {
                "name": "Y.F. Lai",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.B. Lan",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "P.F. Lang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "A. Lankford",
                "org": "University of California at Irvine"
            },
            {
                "name": "F. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "P.Q. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Q. Li",
                "org": "Shandong University"
            },
            {
                "name": "R.B. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W.D. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W.G. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.H. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.N. Li",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.Z. Lin",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.M. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.H. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Q. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "R.G. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.A. Liu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.C. Lou",
                "org": "University of Texas at Dallas"
            },
            {
                "name": "B. Lowery",
                "org": "University of Texas at Dallas"
            },
            {
                "name": "J.G. Lu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S. Luo",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y. Luo",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "A.M. Ma",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "E.C. Ma",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.M. Ma",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.S. Mao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.P. Mao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "R. Malchow",
                "org": "Colorado State University"
            },
            {
                "name": "M. Mandelkern",
                "org": "University of California at Irvine"
            },
            {
                "name": "X.C. Meng",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.L. Ni",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Nie",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.L. Olsen",
                "org": "University of Hawai'i"
            },
            {
                "name": "J. Oyang",
                "org": "California Institute of Technology"
            },
            {
                "name": "D. Paluselli",
                "org": "University of Hawai'i"
            },
            {
                "name": "L.J. Pan",
                "org": "University of Hawai'i"
            },
            {
                "name": "J. Panetta",
                "org": "California Institute of Technology"
            },
            {
                "name": "F. Porter",
                "org": "California Institute of Technology"
            },
            {
                "name": "E. Prabhakar",
                "org": "California Institute of Technology"
            },
            {
                "name": "N.D. Qi",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.K. Que",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Quigley",
                "org": "Massachusetts Institute of Technology"
            },
            {
                "name": "G. Rong",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M. Schernau",
                "org": "University of California at Irvine"
            },
            {
                "name": "B. Schmid",
                "org": "University of California at Irvine"
            },
            {
                "name": "J. Schultz",
                "org": "University of California at Irvine"
            },
            {
                "name": "Y.Y. Shao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "D.L. Shen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H. Shen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.Y. Shen",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.Y. Sheng",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.Z. Shi",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.R. Shi",
                "org": "California Institute of Technology"
            },
            {
                "name": "A. Smith",
                "org": "University of California at Irvine"
            },
            {
                "name": "E. Soderstrom",
                "org": "Stanford Linear Accelerator Center"
            },
            {
                "name": "X.F. Song",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Standifird",
                "org": "University of Texas at Dallas"
            },
            {
                "name": "D. Stoker",
                "org": "University of California at Irvine"
            },
            {
                "name": "F. Sun",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.S. Sun",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.J. Sun",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Synodinos",
                "org": "Stanford Linear Accelerator Center"
            },
            {
                "name": "Y.P. Tan",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.Q. Tang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W. Toki",
                "org": "Colorado State University"
            },
            {
                "name": "G.L. Tong",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "E. Torrence",
                "org": "Massachusetts Institute of Technology"
            },
            {
                "name": "F. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "L.S. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "L.Z. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "P. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "P.L. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.M. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "T.J. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.Y. Wang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.L. Wei",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S. Whittaker",
                "org": "Boston University"
            },
            {
                "name": "R. Wilson",
                "org": "Colorado State University"
            },
            {
                "name": "W.J. Wisniewski",
                "org": "Stanford Linear Accelerator Center"
            },
            {
                "name": "D.M. Xi",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.M. Xia",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "P.P. Xie",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "D.Z. Xu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "R.S. Xu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.Q. Xu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.T. Xue",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "R. Yamamoto",
                "org": "Massachusetts Institute of Technology"
            },
            {
                "name": "J. Yan",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W.G. Yan",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.M. Yang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.Y. Yang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W. Yang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M.H. Ye",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.Z. Ye",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "K. Young",
                "org": "University of Washington"
            },
            {
                "name": "C.S. Yu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.X. Yu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.Q. Yu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.Z. Yuan",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "B.Y. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "C.C. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "D.H. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.L. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.W. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "L.S. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "S.Q. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.Y. Zhang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "D.X. Zhao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.W. Zhao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.W. Zhao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "M. Zhao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "W.R. Zhao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.P. Zheng",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "L.S. Zheng",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.P. Zheng",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "G.P. Zhou",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "H.S. Zhou",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "L. Zhou",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "X.F. Zhou",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.H. Zhou",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Q.M. Zhu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.C. Zhu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y.S. Zhu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "B.A. Zhuang",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "G. Zioulas",
                "org": "University of California at Irvine"
            }
        ],
        "title": "Evidence for the leptonic decay D \u2192 \u03bc\u03bd",
        "keywords": [
            ""
        ],
        "venue": "Physics Letters, Section B: Nuclear, Elementary Particle and High-Energy Physics",
        "year": 1998,
        "id": "ay0DSoXT"
    },
    "hXrEYC3t": {
        "authors": [
            {
                "name": "F.H. Qiu",
                "org": "Inst. of Pharmacol. and Toxicology"
            },
            {
                "name": "L. Liu",
                "org": "Inst. of Pharmacol. and Toxicology"
            },
            {
                "name": "Y. Luo",
                "org": "Inst. of Pharmacol. and Toxicology"
            },
            {
                "name": "F. Liu",
                "org": "Inst. of Pharmacol. and Toxicology"
            },
            {
                "name": "Y.Q. Lu",
                "org": "Inst. of Pharmacol. and Toxicology"
            }
        ],
        "title": "Systematic analysis of basic drugs in plasma using X-5 solid-phase extraction GC-FID and GC MS",
        "abstract": "A systematic determination method for 34 basic drugs in human plasma is described. Drugs were extracted from plasma at pH 10 using X-5 resin as adsorbent, then identified and quantitated by capillary GC-FID and GC-MS. The detection limits for most drugs are in the range of 0.5\u223c2.0 \u03bcg\u2022ml",
        "keywords": [
            "Basic drugs",
            "GC-FID",
            "GC-MS",
            "Solid-phase extraction"
        ],
        "venue": "Yaoxue Xuebao",
        "year": 1996,
        "id": "hXrEYC3t"
    },
    "ZV7tks2d": {
        "authors": [
            {
                "name": "F.H. Qiu",
                "org": "Inst. of Toxicology and Pharmacology"
            },
            {
                "name": "L. Liu",
                "org": "Inst. of Toxicology and Pharmacology"
            },
            {
                "name": "Y. Luo",
                "org": "Inst. of Toxicology and Pharmacology"
            },
            {
                "name": "Y.Q. Lu",
                "org": "Inst. of Toxicology and Pharmacology"
            }
        ],
        "title": "A double column double pH solid phase extraction and capillary GC/FID method for rapid simultaneous determination of acidic and basic drugs in human plasma",
        "abstract": "A capillary gas chromatographic method for the rapid simultaneous identification and quantitation of acidic and basic drugs in human plasma is presented. A special double column solid phase extraction device was designed, in which two X-5 resin columns can extract drugs at different pH. The detection limits for acidic and basic drugs can reach 0. 5 \u03bcg\u00b7ml",
        "keywords": [
            "Capillary GC/FID",
            "Double column double pH solid phase extraction"
        ],
        "venue": "Yaoxue Xuebao",
        "year": 1996,
        "id": "ZV7tks2d"
    },
    "I5XOnoFm": {
        "authors": [
            {
                "name": "H.F. Wu",
                "org": "Inst. of Pharmacology and Toxicology"
            },
            {
                "name": "F.Y. Guan",
                "org": "Inst. of Pharmacology and Toxicology"
            },
            {
                "name": "Y. Luo",
                "org": "Inst. of Pharmacology and Toxicology"
            }
        ],
        "title": "A systematic screening and identification method for 29 central nervous system drugs in body fluid by high performance capillary electrophoresis",
        "abstract": "A systematic screening method has been developed for the detection of 29 central nervous system (CNS) drugs in human plasma, urine and gastric juice by high performance capillary electrophoresis (HPCE). The first step is sample preparation. The patient's or normal human plasma (0.5 ml) spiked with CNS drugs was extracted with 2 X 4 ml dichloromethane, while 2 ml of patient's or spiked urine was extracted with 2 X 6 ml chloroform. The combined extract from plasma or urine was evaporated to dryness in a rotation evaporator at 35\u00b0C . The residue was dissolved in 100 \u03bcl methanol and subsequently 400 \u03bcl of redistilled water was added. The patient gastric juice (3 ml) was centrifuged at 2 000 r\u00b7min",
        "keywords": [
            "Barbiturates",
            "Benzodiazepines",
            "High performance capillary electrophoresis (HPCE)",
            "Micellar electrokinetic chromatography (MEKC)",
            "Systematic drug screening",
            "Thiodiphenylamines"
        ],
        "venue": "Yaoxue Xuebao",
        "year": 1997,
        "id": "I5XOnoFm"
    },
    "EsNZJ2xg": {
        "authors": [
            {
                "name": "Z.Y. Jin",
                "org": "Inst. of Pharmacology and Toxicology"
            },
            {
                "name": "M.S. Gu",
                "org": "Inst. of Pharmacology and Toxicology"
            },
            {
                "name": "Y. Luo",
                "org": "Inst. of Pharmacology and Toxicology"
            }
        ],
        "title": "Quantitative analysis of soporific sedative drugs and local anesthetic drugs with unidentical standard substance by GC-AED",
        "abstract": "According to the principle of GC-AED (gas chromatography-atomic emission detector), the possibility of quantitative determination of samples by different substances as internal standard was studied. The element C was determined at wavelength of 496 nm. The relative response factors of 17 soporific sedative and local anesthetic drugs were analyzed with an internal standard of proadifen hydrochloride under optimized analytical conditions. Oven temp.: 45\u00b0C (0.5 min)-35\u00b0C \u00b7 min",
        "keywords": [
            "Gas chromatography - Atomic emission detector",
            "Local anesthetic drugs",
            "Soporific and sedative drugs"
        ],
        "venue": "Yaoxue Xuebao",
        "year": 1997,
        "id": "EsNZJ2xg"
    },
    "Ghl9bzfn": {
        "authors": [
            {
                "name": "A. Koole",
                "org": "Dept. of Analyt. Chem. and Toxicol."
            },
            {
                "name": "Y. Luo",
                "org": "Inst. of Pharmacology and Toxicology"
            },
            {
                "name": "J.P. Franke",
                "org": "Dept. of Analyt. Chem. and Toxicol."
            },
            {
                "name": "R.A. De Zeeuw",
                "org": "Dept. of Analyt. Chem. and Toxicol."
            }
        ],
        "title": "Dramatic signal reduction in ion-mobility spectrometry by residues of solvents",
        "abstract": "During our evaluation of ion-mobility spectrometry (IMS) screening for the abuse of the \u03b2-agonist clenbuterol during fattening in cattle, we found that clenbuterol could not be detected with the instrument in extracts obtained by solid-phase extraction or ionpair extraction, although the recovery for these procedures was at least 85%. Several experiments showed that the signal loss occurred mainly during the evaporation of the organic solvent. Again, it could be shown that no clenbuterol was lost during this step. On further investigation, we found that so-called solvent residues, which are left after the evaporation of the organic solvent, caused a significant reduction of the clenbuterol signal. Other reagents used in our sample pretreatment procedures were also found to reduce the signal. For example, the signal reductions caused by the different reagents used for the ion-pair extraction of clenbuterol from human urine were determined. We think that IMS is only useful for our purpose if a chromatographic preseparation is performed.",
        "keywords": [
            ""
        ],
        "venue": "Journal of Analytical Toxicology",
        "year": 1998,
        "id": "Ghl9bzfn"
    },
    "7kk3KBtR": {
        "authors": [
            {
                "name": "A. Koole",
                "org": "University Centre for Pharmacy"
            },
            {
                "name": "A.C. Jetten",
                "org": "University Centre for Pharmacy"
            },
            {
                "name": "Y. Luo",
                "org": "Inst. of Pharmacology and Toxicology"
            },
            {
                "name": "J.P. Franke",
                "org": "University Centre for Pharmacy"
            },
            {
                "name": "R.A. De Zeeuw",
                "org": "University Centre for Pharmacy"
            }
        ],
        "title": "Rapid extraction of clenbuterol from human and calf urine using empore(TM) C8 extraction disks",
        "abstract": "In the present paper, disk extraction was evaluated for the rapid isolation of clenbuterol from human and calf urine, followed by high- performance liquid chromatography analysis with UV detection. A method was developed for the extraction with standard density C8 disks. The disks could be washed with 25% methanol in 0.01M sodium hydroxide without significant losses of clenbuterol. The recovery of clenbuterol was about 85%, and the extracts were clean. The detection limit was about 10 ng/mL. The main advantages of these disks were the saving of time and the reduced amounts of organic solvents needed.",
        "keywords": [
            ""
        ],
        "venue": "Journal of Analytical Toxicology",
        "year": 1999,
        "id": "7kk3KBtR"
    },
    "GD7xJOEH": {
        "authors": [
            {
                "name": "Y. Luo",
                "org": "Shanghai Tiedao Univ"
            },
            {
                "name": "H. Yin",
                "org": "Shanghai Tiedao Univ"
            },
            {
                "name": "C. Hua",
                "org": "Shanghai Tiedao Univ"
            }
        ],
        "title": "Dynamic response of railway ballast to the action of trains moving at different speeds",
        "abstract": "To study the dynamic response of railway ballast excited by forces from the moving train at different speeds, a finite element model of track is developed. The rail is represented by a Timoshenko beam on discrete pad-sleeper-ballast supports. The ballast is considered as a three-dimensional finite element model. Wheel/rail irregularities and moving loads are taken into account. The displacement, acceleration and dynamic stress at different parts of the ballast are calculated. Vibration propagation is also presented. The responses of ballast, for constant loads and travelling at constant speeds over track with and without irregularity, are studied. It is shown that, at high speeds, stone may be projected out of the ballast bed.",
        "keywords": [
            ""
        ],
        "venue": "Proceedings of the Institution of Mechanical Engineers, Part F: Journal of Rail and Rapid Transit",
        "year": 1996,
        "id": "GD7xJOEH"
    },
    "kd2Xevk5": {
        "authors": [
            {
                "name": "Y. Luo",
                "org": "Institute of Wheel/Rail System"
            }
        ],
        "title": "A model for predicting the effect of temperature force of continuous welded rail track",
        "abstract": "This paper presents a method for investigating the dynamic characteristic of railway continuous welded rail (CWR) track subjected to the longitudinal force in the rail owing to fluctuation in temperature. The influences of the temperature force on the vibration modes and resonant frequencies are analysed with a harmonically varying, transverse, concentrated force at the centre of one span of the rail. The effects of track parameters such as rail mass, support stiffness and support length are also considered. Some conclusions of practical interest are drawn from the study to enhance the understanding of the physical problems of CWR track. \u00a9 IMechE 1999.",
        "keywords": [
            "Continuous welded rail",
            "Mode shapes",
            "Vibration"
        ],
        "venue": "Proceedings of the Institution of Mechanical Engineers, Part F: Journal of Rail and Rapid Transit",
        "year": 1999,
        "id": "kd2Xevk5"
    },
    "jT3fB77i": {
        "authors": [
            {
                "name": "Y. Luo",
                "org": "Railway and Urban Mass Transit Research Institute"
            },
            {
                "name": "L. Li",
                "org": "Railway and Urban Mass Transit Research Institute"
            },
            {
                "name": "H. Yin",
                "org": "Universit\u00e9 Paris-Est UR Navier"
            }
        ],
        "title": "A dynamic analysis of a continuous welded rail track under a longitudinal stress caused by temperature changes",
        "abstract": "This article presents a dynamic computational model for analysing the correlation between rail's natural frequencies and the longitudinal stress generated by temperature variation. The model includes a rail, sleepers, and the foundation. Some factors such as the rail section profile, rail wear, and the stiffness of fasteners are also considered. Based on the model, numerical computational analyses are performed. The relationship between the rail's longitudinal temperature force and the natural frequency is also studied. The influences of parameters such as the wear of the rail, unsupported distance of adjoining sleepers, fastener stiffness, rail types, and foundation stiffness are investigated. A field experiment is also presented that was performed to investigate the relationship between the rail's dynamic characteristics and the longitudinal stress generated by temperature variation with various unsupported sleeper spacings. The results of analysis and in-field measurements are compared.",
        "keywords": [
            "Continuous welded rail track",
            "Dynamic characteristics",
            "Finite-element method",
            "Longitudinal stress"
        ],
        "venue": "Proceedings of the Institution of Mechanical Engineers, Part F: Journal of Rail and Rapid Transit",
        "year": 2010,
        "id": "jT3fB77i"
    },
    "g5p2EIC7": {
        "authors": [
            {
                "name": "L. Li",
                "org": "Railway and Urban Mass Transit Research Institute"
            },
            {
                "name": "Y. Luo",
                "org": "Railway and Urban Mass Transit Research Institute"
            }
        ],
        "title": "Cwr track vibration characteristics varying with the change of supporting condition",
        "abstract": "Stress contained in rails, mainly due to thermally-induced expansion and contraction, results in large longitudinal loads which lead to broken rails and track buckling. According to the beam bending theory of structural dynamics with a consideration of the influence of axial load, a test method to measure the longitudinal force in CWR is introduced. This paper studied the elements which will affect the results used in this method such as the total calculation and measurement length of rail, unsupported length of rail. Standard relation curve between longitudinal force and first order frequency was provided. To the actual continuous welded rail, longitudinal force can be calculated according to the standard relation curve after the vibration response frequency of rail in some state is measured. This method would help to evaluate and measure the force in rail caused by temperature change. \u00a9 2012 WIT Press.",
        "keywords": [
            "Buckling",
            "Continuous welded rail (CWR)",
            "Natural frequency",
            "Stability",
            "Vibration characteristics"
        ],
        "venue": "WIT Transactions on the Built Environment",
        "year": 2012,
        "id": "g5p2EIC7"
    },
    "sGtVySr4": {
        "authors": [
            {
                "name": "Y. Luo",
                "org": "Department of Geotechnical Engineering"
            },
            {
                "name": "Y. Yuan",
                "org": "Department of Geotechnical Engineering"
            },
            {
                "name": "R. Chai",
                "org": "Hong Kong-Zhuhai-Macao Bridge Authority"
            }
        ],
        "title": "A numerical model in precasting segment of an immersed tunnel",
        "abstract": "Concrete are particularly prone to cracking at the early age due to thermal deformation, shrinkage and creep in precasting. This paper presents a temperature and stress simulation of the tunnel structure based on the precasting process. In the numerical model, the material parameters, thermal parameters and mechanical parameters are obtained via material tests and European code. Material tests include the heat of hydration, strength, modulus of elasticity and autogenous-shrinkage. Moreover, complex thermal boundary and mechanical boundary conditions are considered. The evolution rules of temperature and stress field could be obtained in analysis of typical working condition, In addition, the possible causes of cracks in immersed concrete tunnel, such as the mix proportion of concrete, warehousing temperature and curing temperature are studied, which are of great significance for the security and durability of the tunnel structure. Furthermore, a model experiment is conducted to verify the numerical simulation of tunnel structure.",
        "keywords": [
            "Immersed tunnel",
            "Numerical model",
            "Simulation",
            "Temperature and stress"
        ],
        "venue": "ECCOMAS 2012 - European Congress on Computational Methods in Applied Sciences and Engineering, e-Book Full Papers",
        "year": 2012,
        "id": "sGtVySr4"
    },
    "muzxjLMh": {
        "authors": [
            {
                "name": "Y. Luo",
                "org": "Railway and Urban Rail Transit Research Institute"
            },
            {
                "name": "Y. Liu",
                "org": "Railway and Urban Rail Transit Research Institute"
            },
            {
                "name": "H.P. Yin",
                "org": "Universit\u00e9 Paris-Est"
            }
        ],
        "title": "Numerical investigation of nonlinear properties of a rubber absorber in rail fastening systems",
        "abstract": "A nonlinear dynamic model of a rubber absorber in railway fastening systems is proposed, based on the superposition principle to simulate its nonlinear vibrational behavior. A dynamic experiment was carried out to obtain all model parameters. The accuracy of the model was supported by good agreement between measured and simulated results, and it should therefore be an effective mechanical tool for simulating and characterizing the nonlinear behavior of rubber absorbers in rail fastening systems at particular vibrational modes. Excitation frequency dependency and amplitude dependency of the nonlinear dynamic stiffness were also selected for further study. The results indicate that characteristics of the nonlinear dynamic stiffness are closely associated with both displacement amplitude and frequency, although frequency dependency is not as great as amplitude dependency. \u00a9 2013 Elsevier Ltd.",
        "keywords": [
            "Amplitude dependency",
            "Dynamic stiffness",
            "Frequency dependency",
            "Parameter identification",
            "Rubber absorbers in rail fastening systems"
        ],
        "venue": "International Journal of Mechanical Sciences",
        "year": 2013,
        "id": "muzxjLMh"
    },
    "SOK5uVGm": {
        "authors": [
            {
                "name": "Y. Yuan",
                "org": "Department of Internal Medicine"
            },
            {
                "name": "Z. Wang",
                "org": "Department of Internal Medicine"
            },
            {
                "name": "Y. Luo",
                "org": "Department of Internal Medicine"
            },
            {
                "name": "T. He",
                "org": "Department of Internal Medicine"
            },
            {
                "name": "J. Zeng",
                "org": "Department of Internal Medicine"
            }
        ],
        "title": "Cetirizine improves the resistance of airway and pulmonary function in patients with asthma",
        "abstract": "The objective of this study was to investigate the possible anti-asthma role of Cetirizine. Forty asthmatics were randomly divided into two groups. The experimental group had 30 patients. Among them were 10 patients with simple asthma, 5 patients complicated by mild emphysema, 6 patients complicated by moderate emphysema and 9 patients complicated by severe emphysema. Vit-C (control) group had 10 cases, including 2 cases of simple asthma, 6 cases complicated by mild emphysema and 2 cases complicated by moderate emphysema. All patients had a single oral dose of 5 mg Cetirizine or 0.1 g Vit-C blindly. Before and 0.5, 1 hour after their medicines, the resistance of airway (Raw), sGaw and MEFV were examined in all patients on 6200 Plethysmograph. The measured values showed a significant improvement of Raw and sGaw after administration of Cetirizine. In half an hour after Cetirizine, the Raw decreased by 20.408%, and sGaw increased by 28.249%. In one hour after Cetirizine, Raw further decreased by 24.34% and sGaw increased by 41.153% (P < 0.001). The FVC in MEFV increased by 4.96% (P < 0.02) in one hour after Cetirizine, but other parameters in MEFV curve (PEF, FEV",
        "keywords": [
            "asthma",
            "Cetirizine",
            "maximal expiratory flow-volume curve",
            "resistance of airway"
        ],
        "venue": "Journal of West China University of Medical Sciences",
        "year": 1996,
        "id": "SOK5uVGm"
    },
    "khso8mWn": {
        "authors": [
            {
                "name": "Y. Wang",
                "org": ""
            },
            {
                "name": "Y. Luo",
                "org": ""
            },
            {
                "name": "W. Chen",
                "org": ""
            },
            {
                "name": "Y. Yuan",
                "org": ""
            },
            {
                "name": "T. He",
                "org": ""
            },
            {
                "name": "J. Zeng",
                "org": ""
            }
        ],
        "title": "Effect of methylphenidatum in inspiratory muscles function in patients with chronic obstructive pulmonary disease and its mechanism",
        "abstract": "To have a better understanding of the effect of methylphenidatum on inspiratory muscles function, we studied the respiratory force parameters of 70 patients with chronic obstructive pulmonary disease by intravenous infusion methylphenidatum in a randomized controlled clinical trial. The indices of respiratory force parameter included maximal inspiratory mouth pressure (MIP), maximal midinspiratory flow (MMIF), forced inspiratory capacity (FIC), maximal works of inspiration (Wi(max)) and airway occlusion pressure (P",
        "keywords": [
            "airway occlusion pressure",
            "chronic obstructive pulmonary disease",
            "function of inspiratory muscles",
            "methylphenidatum"
        ],
        "venue": "Journal of West China University of Medical Sciences",
        "year": 1997,
        "id": "khso8mWn"
    },
    "E0kDI4gw": {
        "authors": [
            {
                "name": "X. Chen",
                "org": ""
            },
            {
                "name": "Y. Feng",
                "org": ""
            },
            {
                "name": "Y. Luo",
                "org": ""
            },
            {
                "name": "Y. Yuan",
                "org": ""
            },
            {
                "name": "T. He",
                "org": ""
            },
            {
                "name": "J. Zeng",
                "org": ""
            }
        ],
        "title": "The effect of leukotriene antagonist on the parameters of dose-response curve obtained after methacholine challenge test",
        "abstract": "Objective: To investigate the effect of leukotriene antagonist (zafirlucast) on the parameters of dose-response curve (DRC) obtained after methacholine challenge test. Methods: A therapy trial was conducted with the use of zafirlucast in 20 cases of cough variant asthma (CVA) and 20 cases of asthma. Placeba was used in 4 cases of CVA and 10 cases of asthma for comparison with the two therapy groups respectively. Before and after the zafirlucast treatment a series of parameters of DRC were obtained after the methacholine challenge test and were calculated. These included the response threshold (PC35sGaw), the dose-response slope (DRS), the ratio of the area under the curve to the logarithm of the maximal concentration (AUC/lg[Cmax]), and the maximal response. Results: Zafirlucast significantly increased the PC35sGaw in the CVA and asthma groups. It conspicuously decreased all the parameters of DRS and AUC/lg[Cmax] except for maximal response in the cases of CVA, and it had no significant effects on all the parameters of DRS and AUC/lg[Cmax] except for PC35sGaw in the cases of asthma. Conclusion: Short-term use of zafirlucast in asthmatic patients could improve the parameters of dose-response curve obtained after the methacholine challenge test.",
        "keywords": [
            "Asthma",
            "Bronchial challenge test",
            "Dose-response curve",
            "Leukotriene antagonist",
            "Methacholine"
        ],
        "venue": "Journal of West China University of Medical Sciences",
        "year": 2001,
        "id": "E0kDI4gw"
    },
    "WnoCnB46": {
        "authors": [
            {
                "name": "Y. Cai",
                "org": "Department of Respiratory Disease"
            },
            {
                "name": "Y. Feng",
                "org": "Department of Respiratory Disease"
            },
            {
                "name": "Y. Luo",
                "org": "Department of Respiratory Disease"
            },
            {
                "name": "Y. Wu",
                "org": "Department of Respiratory Disease"
            },
            {
                "name": "Y. Luo",
                "org": "Department of Respiratory Disease"
            },
            {
                "name": "Y. Li",
                "org": "Department of Respiratory Disease"
            },
            {
                "name": "G. Zhou",
                "org": "Department of Respiratory Disease"
            },
            {
                "name": "Z. Xie",
                "org": "Department of Respiratory Disease"
            }
        ],
        "title": "A multi-centered clinical study an domestic intravenous Turbutalin Sulfate in the treatment of asthma and chronic asthmatic bronchitis",
        "abstract": "Objective: This multi-centered clinical trial was designed to assess the efficacy and safety of domestic intravenous Turbutalin Sulfate in the treatment of asthma and chronic asthmatic bronchitis. Methods: Bricanyl was used as control. A total of 120 patients were included in this randomized controlled study. The two medications, both ar a dose of 0.25 mg intravenous drip, were given three times a day for 3-5 days. Results: The two drugs' clinical excellent tares were 66.7% and 73. 3% overall efficacy rates were 98.3% and 100.0%, respectively. Their pulmonary functional excellent rates were 78.4% and 76.6%; overall effect tares were 88.3% and 90.0% respectively. Composite curative evaluation showed that the two drug's composite excellent rates were 61.6% both; their overall efficacy rates were 88.3% and 90.0%, respectively. All of these showed no significant difference (P > 0.05). The incidence rates of adverse side effects of the two groups were 13.5% and 15.0% respectively; most of them were mild and tolerable. Conclusion: Domestic intravenous Terbutalin Sulfate is effective and safe in treating asthma and chronic asthmatic bronchitis.",
        "keywords": [
            "Asthma",
            "Bricanyl",
            "Randomized controlled trial",
            "Terbutalin sulfate"
        ],
        "venue": "Journal of West China University of Medical Sciences",
        "year": 2001,
        "id": "WnoCnB46"
    },
    "tALnzeyg": {
        "authors": [
            {
                "name": "Y. Yuan",
                "org": "Department of Internal Medicine"
            },
            {
                "name": "T. He",
                "org": "Department of Internal Medicine"
            },
            {
                "name": "L. Wang",
                "org": "Department of Internal Medicine"
            },
            {
                "name": "J. Zeng",
                "org": "Department of Internal Medicine"
            },
            {
                "name": "Y. Luo",
                "org": "Department of Internal Medicine"
            }
        ],
        "title": "A comparison between the effects of albuterol and isoproterenol in bronchodilation test",
        "abstract": "Objective: To compare albuterol with isoproterenol as a bronchodilator in pulmonary function test and their value in the diagnosis and differential diagnosis of asthma. Methods: Two groups (59 patients with asthma and 37 patients with COPD) were included in this study, and the patients of each group were randomly divided into 2 subgroups. The patients in the 2 subgroups inspired the two drugs in a cross-over by odd or even days. The pulmonary functions were evaluated. Results: The changing rates of pulmonary functions induced by the two drugs in the two groups were positively correlated (P<0. 005), The changing rates of FEV",
        "keywords": [
            "Albuterol",
            "Bronchodilation test",
            "Isoproterenol",
            "Pulmonary function"
        ],
        "venue": "Journal of West China University of Medical Sciences",
        "year": 2001,
        "id": "tALnzeyg"
    },
    "tOcGqaEe": {
        "authors": [
            {
                "name": "Y. Luo",
                "org": "Univ of Hong Kong"
            },
            {
                "name": "S.C. Chan",
                "org": "Univ of Hong Kong"
            },
            {
                "name": "K.L. Ho",
                "org": "Univ of Hong Kong"
            }
        ],
        "title": "Theory and design of arbitrary-length biorthogonal cosine-modulated filter banks",
        "abstract": "The design and generalization of Perfect-reconstruction (PR) cosine-modulated filter banks (CMFB) have been studied extensively due to its low design and implementation complexity. In this paper, the theory and design of arbitrary-length biorthogonal CMFB is considered. This is a generalization of the method used in [5] for designing arbitrary length orthogonal CMFB and has the advantage of simple design procedure. We also propose a systematic design method so that biorthogonal CMFB with longer length can be obtained.",
        "keywords": [
            ""
        ],
        "venue": "Proceedings - IEEE International Symposium on Circuits and Systems",
        "year": 1997,
        "id": "tOcGqaEe"
    },
    "2vSj25FT": {
        "authors": [
            {
                "name": "S.C. Chan",
                "org": "Univ of Hong Kong"
            },
            {
                "name": "Y. Luo",
                "org": "Univ of Hong Kong"
            },
            {
                "name": "K.L. Ho",
                "org": "Univ of Hong Kong"
            }
        ],
        "title": "M-channel cosine-modulated wavelet bases",
        "abstract": "In this paper, we propose a new M-channel wavelet bases called the cosine-modulated wavelets. We first generalize the theory of two-channel biorthogonal compactly supported wavelet bases to the M-channel case. A sufficient condition for the M-channel perfect reconstruction filter banks to construct M-channel compactly supported wavelet bases is given. By using this condition, a family of orthogonal and biorthogonal M-channel cosine-modulated wavelet bases is constructed by iterations of cosine-modulated filter banks (CMFB). The advantages of the approach are their simple design procedure, efficient implementation and good filter quality. A method for imposing the regularity on the cosine-modulated filter banks is also introduced and design example is given.",
        "keywords": [
            ""
        ],
        "venue": "International Conference on Digital Signal Processing, DSP",
        "year": 1997,
        "id": "2vSj25FT"
    },
    "gxUvLoEl": {
        "authors": [
            {
                "name": "S.C. Chan",
                "org": "Department of Electrical Engineering"
            },
            {
                "name": "Y. Luo",
                "org": "Department of Electrical Engineering"
            },
            {
                "name": "K.L. Ho",
                "org": "Department of Electrical Engineering"
            }
        ],
        "title": "M-Channel compactly supported biorthogonal cosine-modulated wavelet bases",
        "abstract": "In this correspondence, we generalize the theory of compactly supported biorthogonal two-channel wavelet bases to M -channel. A sufficient condition for the M-channel perfect reconstruction filter banks to construct M-channel biorthogonal bases of compactly supported wavelets is derived. It is shown that the construction of biorthogonal Af-channel wavelet bases is equivalent to the design of a Af-channel perfect reconstruction filter bank with some added regularity conditions. A family of M-channel biorthogonal wavelet bases based on the cosinemodulated filter bank (CMFB) is proposed. It has the advantages of simple design procedure, efficient implementation, and good filter quality. A new method for imposing the regularity on the CMFB's is also introduced, and several design examples are given. \u00a91998 IEEE.",
        "keywords": [
            ""
        ],
        "venue": "IEEE Transactions on Signal Processing",
        "year": 1998,
        "id": "gxUvLoEl"
    },
    "WbujZUzh": {
        "authors": [
            {
                "name": "Y. Luo",
                "org": "Faculty of Dentistry"
            },
            {
                "name": "F.R. Tay",
                "org": "Faculty of Dentistry"
            },
            {
                "name": "E.C.M. Lo",
                "org": "Faculty of Dentistry"
            },
            {
                "name": "S.H.Y. Wei",
                "org": "Faculty of Dentistry"
            }
        ],
        "title": "Marginal adaptation of a new compomer under different conditioning methods",
        "abstract": "Objectives: This in vitro study evaluated the marginal adaptation of compomer restorations placed using three different conditioning protocols. Materials and methods: Thirty extracted caries-free molars with 3 mm diameter cylindrical cavity preparations were divided randomly into three groups based upon the conditioning treatment used: (I) 36% phosphoric acid; (II) non-rinse conditioner (NRC, Dentsply DeTrey); and (III) no conditioning. Cavities were restored with Dyract AP using Prime&Bond NT (Dentsply DeTrey) as an adhesive. Silicone impressions of the briefly etched enamel surfaces were taken after finishing the restorations. Each sample was then longitudinally sectioned and impressions were taken. Epoxy resin replicas were prepared for SEM analysis. Qualitative and quantitative assessment were performed separately for the enamel- and dentine-restorative interface. Results: Enamel fractures and open margins along the enamel-restorative margin were observed in some specimens in each group. No statistically significant difference was found in the percentage of gaps/cohesive failures between specimens prepared using different conditioning methods. For the dentine-restorative interface, uniform hybrid layers and long resin tags were often observed in Groups I and II. The hybrid layer in Group III was irregular and discontinuous along the interface. A significant difference (p < 0.01) in the proportion of marginal gap was found between Group I (2%) and Group III (30%). Conclusions: Pre-treating the cavity with 36% phosphoric acid significantly improved the adaptation of the compomer and adhesive to dentine compared with no etching. The marginal quality at the enamel-compomer interface was not affected by the conditioning method used. \u00a9 2000 Elsevier Science Ltd. All rights reserved.",
        "keywords": [
            "Conditioning",
            "In vitro test",
            "Marginal adaptation",
            "Polyacid-modified composite resin"
        ],
        "venue": "Journal of Dentistry",
        "year": 2000,
        "id": "WbujZUzh"
    },
    "5X8An1fz": {
        "authors": [
            {
                "name": "Y. Luo",
                "org": "University of Hong Kong"
            },
            {
                "name": "Edward C. M. Lo",
                "org": "University of Hong Kong"
            },
            {
                "name": "Daniel T. S. Fang",
                "org": "University of Hong Kong"
            },
            {
                "name": "Stephen H. Y. Wei",
                "org": "University of Hong Kong"
            }
        ],
        "title": "Clinical evaluation of polyacid-modified resin composite posterior restorations: One-year results",
        "abstract": "Objective: The aim of this investigation was to evaluate the clinical performance of a new compomer restorative system, Dyract AP, placed in combination with Non-Rinse Conditioner and Prime & Bond NT in permanent posterior teeth. Method and materials: Fifty Class II and 41 Class I restorations were placed in 39 patients by 1 dentist. The restorations were evaluated directly, with modified US Public Health Service criteria, and indirectly, with color slides and polyvinyl siloxane impressions, at baseline and 6 months and 1 year after placement. Preoperative and 1-year postoperative bitewing radiographs were also taken. Results: All 82 restorations available for 1-year evaluation were in situ. No postoperative sensitivity or pulpal problems were reported. Four Class II restorations (4.9%) failed because of partial fracture or recurrent caries. The percentages of Alfa score for each criterion were color match, 95.1%; marginal discoloration, 57.3%; marginal integrity, 35.4%; anatomic form, 98.8%; and surface texture, 91.5%. The average wear rate of Dyract AP was low (18.5 \u00b1 11.7 \u03bcm at 6 months and 35.7 \u00b1 13.6 \u03bcm at 12 months). Conclusion: The excellent handling characteristics, the good clinical performance, and the improved wear resistance suggest that this compomer will provide reliable direct tooth-colored restorations in stress-bearing areas.",
        "keywords": [
            "Clinical evaluation",
            "Compomer",
            "Polyacid-modified resin composite",
            "Wear"
        ],
        "venue": "Quintessence International",
        "year": 2000,
        "id": "5X8An1fz"
    },
    "83SsrSIj": {
        "authors": [
            {
                "name": "E.C.M. Lo",
                "org": "Faculty of Dentistry"
            },
            {
                "name": "Y. Luo",
                "org": "Faculty of Dentistry"
            },
            {
                "name": "M.W. Fan",
                "org": "School of Stomatology"
            },
            {
                "name": "S.H.Y. Wei",
                "org": "Clinical Affairs"
            }
        ],
        "title": "Clinical Investigation of Two Glass-Ionomer Restoratives Used with the Atraumatic Restorative Treatment Approach in China: Two-Years Results",
        "abstract": "Objective: To compare the clinical performance of two glass-ionomer cements, ChemFlex (Dentsply DeTrey) and Fuji IX GP (GC), when used with the atraumatic restorative treatment (ART) approach in China. Methods: Eighty-nine school children aged between 6 and 14 years who had bilateral matched pairs of carious posterior teeth were included. A split-mouth design was used in which the two materials were randomly placed on contralateral sides. The performance of the restorations was assessed directly and also indirectly from die-stone replicas at baseline and after 6, 12, and 24 months. Results: The 24-month cumulative survival rates of ART restorations in the primary teeth were 93 and 90% for the ChemFlex and Fuji IX GP class I restorations, respectively, while 40 and 46% of class II restorations placed with the respective materials were satisfactory. In the permanent dentition, only class I restorations were involved and the cumulative survival rates were 95 and 96% for ChemFlex and Fuji IX GP. For the primary teeth after 24 months, net mean occlusal wear was 87 \u03bcm for ChemFlex and 85 \u03bcm for Fuji IX GP. The occlusal wear in the permanent teeth was 75 \u03bcm for ChemFlex and 79 \u03bcm for Fuji IX GP. Conclusion: The clinical performance of both materials over a 24-month period was similar and the survival rates of class I ART restorations in both primary and permanent teeth were high. Copyright \u00a9 2001 S. Karger AG, Basel.",
        "keywords": [
            "Atraumatic restorative treatment",
            "Clinical evaluation method",
            "Dental material",
            "Glass-ionomer",
            "Restoration wear"
        ],
        "venue": "Caries Research",
        "year": 2001,
        "id": "83SsrSIj"
    },
    "LtoTJPzj": {
        "authors": [
            {
                "name": "Y. Luo",
                "org": "Faculty of Dentistry"
            },
            {
                "name": "E.C.M. Lo",
                "org": "Faculty of Dentistry"
            },
            {
                "name": "S.H.Y. Wei",
                "org": "Faculty of Dentistry"
            },
            {
                "name": "F.R. Tay",
                "org": "Faculty of Dentistry"
            }
        ],
        "title": "Comparison of pulse activation vs conventional light-curing on marginal adaptation of a compomer conditioned using a total-etch or a self-etch technique",
        "abstract": "Objectives: This study investigated the effect of two factors: conditioning methods and light-curing techniques on the marginal adaptation of Dyract AP (Dentsply DeTrey, Germany). The 'pulse activation' curing technique was compared with a conventional light-curing technique for their effectiveness in reducing marginal gaps in restorations that were conditioned with three different protocols. Materials and methods: Cylindrical cavities, 3mm in diameter, were prepared in extracted human molar teeth. They were restored with Dyract AP using Prime&Bond NT (PBNT; Dentsply DeTrey) as the adhesive. Cavities were etched with: Conditioner36/PBNT (group 1), Non-Rinse Conditioner (NRC)/PBNT (group 2), and PBNT only (group 3). Either conventional or the 'pulse activation' technique was used for light-curing of the material. Epoxy resin replicas were obtained from longitudinal sections of the specimens, and the restoration-tooth interfaces were examined using scanning electron microscopy. Marginal qualities along the resin-dentin interfaces were further measured using image analysis and analyzed using nonparametric statistical methods. Results: With the conventional curing technique, enamel margin fractures were frequently observed. Marginal gaps were found along the compomer-dentin interfaces irrespective of the conditioning protocol. A significantly lower percentage of gap-containing margins were found in cavities that were conditioned with 36% phosphoric acid. With the 'pulse activation' technique, no marginal gap was found along compomer-dentin interfaces that were etched with either Conditioner36 or NRC. More than 90% of the total margin length were excellent. No cohesive failure of enamel could be observed along cavosurface margins. Significance: The 'pulse activation' curing technique significantly improves the marginal integrity of Dyract AP when Conditioner36/Prime&Bond NT and NRC/Prime&Bond NT are used as conditioning/bonding systems. The use of Prime&Bond NT without etching is not recommended, as marginal gaps are present irrespective of the curing techniques employed. \u00a9 2002 Academy of Dental Materials. Published by Elsevier Science Ltd. All rights reserved.",
        "keywords": [
            "Dental material",
            "Light-curing technique",
            "Marginal quality",
            "Restoration"
        ],
        "venue": "Dental Materials",
        "year": 2002,
        "id": "LtoTJPzj"
    },
    "PPQtNLW0": {
        "authors": [
            {
                "name": "C. McGrath",
                "org": "Faculty of Dentistry"
            },
            {
                "name": "M.B. Comfort",
                "org": "Faculty of Dentistry"
            },
            {
                "name": "E.C.M. Lo",
                "org": "Faculty of Dentistry"
            },
            {
                "name": "Y. Luo",
                "org": "Faculty of Dentistry"
            }
        ],
        "title": "Changes in life quality following third molar surgery - The immediate postoperative period",
        "abstract": "Objectives: This study describes patients' perceptions of changes in oral health related quality of life (OHQOL) in the early postoperative period following third molar surgery. Methods: One hundred patients were enrolled in a prospective cohort study of the surgical removal of lower third molars under local anaesthetic. Two specific oral health related quality of life measures, OHIP-14 and OHQoLUK\u00a9 were administered to the study group prior to surgery. Standardized surgical and analgesic protocols were followed. Patients kept a diary of changes in life quality each postoperative day (POD) for 7 days, completing both OHIP-14 and OHQoLUK\u00a9 daily. Results: Both oral health related quality of life measures identified a significant deterioration in quality of life on POD1 (P<0.01) and this remained evident on POD2 (P<0.01), POD3 (P<0.01), POD4 (P<0.01) and POD5 (P<0.05). By POD6 and POD7 there was no significant difference in quality of life compared with preoperative status (P>0.05). Deterioration in life quality over the study period was associated with postoperative clinical findings (P<0.05): swelling and trismus. Conclusion: The study concludes that there is a significant deterioration in oral health related quality of life in the immediate postoperative period following third molar surgery; particularly during the first five days. This is associated with postoperative clinical findings. This has implication for patients deciding on third molar surgery and informed consent.",
        "keywords": [
            ""
        ],
        "venue": "British Dental Journal",
        "year": 2003,
        "id": "PPQtNLW0"
    },
    "KQ15NfxB": {
        "authors": [
            {
                "name": "Y. Luo",
                "org": "Dental Public Health"
            },
            {
                "name": "X.J. Zeng",
                "org": "Hospital of Stomatology"
            },
            {
                "name": "M.Q. Du",
                "org": "Department of Preventive Dentistry"
            },
            {
                "name": "R. Bedi",
                "org": "Natl. Ctr. Transcultural Oral Hlth."
            }
        ],
        "title": "The prevalence of dental erosion in preschool children in China",
        "abstract": "Objective. To describe the prevalence of dental erosion and associated factors in preschool children in Guangxi and Hubei provinces of China. Methods. Dental examinations were carried out on 1949 children aged 3-5 years. Measurement of erosion was confined to primary maxillary incisors. The erosion index used was based upon the 1993 UK National Survey of Children's Dental Health. The children's general information as well as social background and dietary habits were collected based on a structured questionnaire. Results. A total of 112 children (5.7%) showed erosion on their maxillary incisors. Ninety-five (4.9%) was scored as being confined to enamel and 17 (0.9%) as erosion extending into dentine or pulp. There was a positive association between erosion and social class in terms of parental education. A significantly higher prevalence of erosion was observed in children whose parents had post-secondary education than those whose parents had secondary or lower level of education. There was also a correlation between the presence of dental erosion and intake of fruit drink from a feeding bottle or consumption of fruit drinks at bedtime. Conclusion. Erosion is not a serious problem for dental heath in Chinese preschool children. The prevalence of erosion is associated with social and dietary factors in this sample of children. \u00a9 2004 Elsevier Ltd. All rights reserved.",
        "keywords": [
            "Dental erosion",
            "Dietary habits",
            "Prevalence",
            "Social class"
        ],
        "venue": "Journal of Dentistry",
        "year": 2005,
        "id": "KQ15NfxB"
    },
    "rw3Jiydy": {
        "authors": [
            {
                "name": "E.C.M. Lo",
                "org": "Faculty of Dentistry"
            },
            {
                "name": "Y. Luo",
                "org": "Faculty of Dentistry"
            },
            {
                "name": "H.P. Tan",
                "org": "Faculty of Dentistry"
            },
            {
                "name": "J.E. Dyson",
                "org": "Faculty of Dentistry"
            },
            {
                "name": "E.F. Corbet",
                "org": "Faculty of Dentistry"
            }
        ],
        "title": "ART and conventional root restorations in elders after 12 months",
        "abstract": "Successful use of atraumatic restorative treatment (ART) in children has been reported, but little information is available regarding its use in older adults. The hypothesis of this study was that survival rates of root restorations placed by both ART and the conventional technique were similar. Root-surface caries lesions in 103 institutionalized elders in Hong Kong were treated randomly by either: (1) the conventional approach-caries removed by dental burs, and the cavity filled with light-cured resin-modified glass ionomer; or (2) the ART approach-caries removed by hand instruments, and the cavity filled with chemically cured high-strength glass ionomer. In total, 84 conventional and 78 ART restorations were placed. After 12 months, 63 conventional and 59 ART restorations were reviewed, and the respective 12-month survival rates were 91.7% and 87.0% (p > 0.05). It is concluded that the survival rates of both types of root restorations were high and similar.",
        "keywords": [
            "Age",
            "Atraumatic restorative treatment",
            "Chinese",
            "Clinical trial",
            "Glass-ionomer cement",
            "Restoration survival",
            "Root caries"
        ],
        "venue": "Journal of Dental Research",
        "year": 2006,
        "id": "rw3Jiydy"
    },
    "Dv9yLOg9": {
        "authors": [
            {
                "name": "A.S. McMillan",
                "org": ""
            },
            {
                "name": "M.C.M. Wong",
                "org": ""
            },
            {
                "name": "J. Zheng",
                "org": ""
            },
            {
                "name": "Y. Luo",
                "org": ""
            },
            {
                "name": "C.L.K. Lam",
                "org": ""
            }
        ],
        "title": "Widespread pain symptoms and psychological distress in southern Chinese with orofacial pain",
        "abstract": "The study investigated the experience of widespread pain (WP) symptoms and psychological distress in southern Chinese with orofacial pain (OFP). A community-based, cross-sectional case-control study involving people aged 35-70 registered with the Hospital Authority/University of Hong Kong Family Medicine Clinic served as the sampling frame. People with recent OFP symptoms and a group without OFP took part. Standard questions were asked about OFP conditions in the previous month. Psychological status was evaluated through depression, and non-specific physical symptoms (NPS) scores were measured with depression and somatization sub-scales of the Symptom Checklist-90. Widespread pain was determined using body outline drawings to identify painful sites prior to a standard clinical examination. Two hundred people with OFP and 200 without OFP participated. Compared with 5\u00b70% in the comparison group (P = 0\u00b7005), 13\u00b75% of participants with OFP had WP (OFP/WP). Multiple OFP symptoms were more common in the OFP/WP sub-group than the OFP sub-group without WP (OFP/No WP) (P < 0\u00b7002). Sixty-three percent of the OFP/WP sub-group had moderate/severe depression scores compared with 26\u00b70% in the OFP/No WP sub-group (P < 0\u00b7001). When pain items were included and excluded, 92\u00b76% and 88\u00b79% of the OFP/WP sub-group had moderate/severe NPS scores, respectively compared with 68\u00b75% and 65\u00b70% in the OFP/No WP sub-group (P = 0\u00b7004). Co-morbid WP occurred relatively often in southern Chinese with OFP. Psychological distress was common in OFP sufferers, particularly those with WP. A multidisciplinary approach to treatment including cognitive/behavioural therapy should be considered in Chinese people with OFP as part of a WP pattern. \u00a9 2009 Blackwell Publishing Ltd.",
        "keywords": [
            "Chinese",
            "Clinical assessment",
            "Depression",
            "Orofacial pain",
            "Psychological",
            "Somatization",
            "Widespread pain"
        ],
        "venue": "Journal of Oral Rehabilitation",
        "year": 2010,
        "id": "Dv9yLOg9"
    },
    "aKHYQByA": {
        "authors": [
            {
                "name": "H.P. Tan",
                "org": "Australian Research Centre for Population Oral Health"
            },
            {
                "name": "E.C.M. Lo",
                "org": "Faculty of Dentistry"
            },
            {
                "name": "J.E. Dyson",
                "org": "Faculty of Dentistry"
            },
            {
                "name": "Y. Luo",
                "org": "Cancer Clinical Trials Office"
            },
            {
                "name": "E.F. Corbet",
                "org": "Faculty of Dentistry"
            }
        ],
        "title": "A randomized trial on root caries prevention in elders",
        "abstract": "Root caries is common in institutionalized elders, and effective prevention methods are needed. This clinical trial compared the effectiveness of four methods in preventing new root caries. From 21 residential homes, 306 generally healthy elders having at least 5 teeth with exposed sound root surfaces were randomly allocated into one of four groups: (1) individualized oral hygiene instruction (OHI); (2) OHI and applications of 1% chlorhexidine varnish every 3 months; (3) OHI and applications of 5% sodium fluoride varnish every 3 months; and (4) OHI and annual applications of 38% silver diamine fluoride (SDF) solution. Two-thirds (203/306) of the elders were followed for 3 years. Mean numbers of new root caries surfaces in the four groups were 2.5, 1.1, 0.9, and 0.7, respectively (ANOVA, p < 0.001). SDF solution, sodium fluoride varnish, and chlorhexidine varnish were more effective in preventing new root caries than giving OHI alone. \u00a9 2010 International & American Associations for Dental Research.",
        "keywords": [
            "chlorhexidine",
            "clinical trial",
            "fluoride",
            "preventive dentistry",
            "root surface caries"
        ],
        "venue": "Journal of Dental Research",
        "year": 2010,
        "id": "aKHYQByA"
    },
    "ryvQOM8O": {
        "authors": [
            {
                "name": "H.-F. Sun",
                "org": "Yangzhou Medical University Hospital"
            },
            {
                "name": "X.-D. Zhang",
                "org": "Yangzhou Medical University Hospital"
            },
            {
                "name": "Y. Luo",
                "org": "Yangzhou Medical University Hospital"
            }
        ],
        "title": "Significance of nitric oxide changes in serum and tumor tissue from gastric cancer patients",
        "abstract": "The levels of nitric oxide (NO) were determined in the serum and tumor tissue from 34 gastric cancer (GC) patients using colorimetry. Serum samples from 30 normal individuals and 30 patients with duodenal ulcer (DU), and 23 paracancerous tissues (PCT) were taken as control. The results revealed that the serum NO levels in GC patients were lower than those in normal individuals and DU patients (P<0.01). Serum NO levels were higher in DU patients than those in the normal controls (P<0.01). Levels of NO in GC tissues, however, were higher than those in PCT group (P<0.01). This study suggests that NO produced by activated macrophagocytes in the tumor tissue plays the part of immunomodulation. It is postulated that NO acts on tumor cells directly and kills the tumor cells by regulating immunosystemic functions in the repairment of damaged mucosa. This explains that NO level decreases in serum, but increases in tissue of gastric cancer. It is inferred that determination of NO in the serum might be helpful in distinguishing benign from malignant disease of the stomach. In light of the dual action of NO, it is suggested that promotion or inhibition of NO synthesis either of them might be beneficial in the treatment of gastric cancer.",
        "keywords": [
            "Duodenal ulcer",
            "Gastric carcinoma",
            "Nitric oxide (NO)"
        ],
        "venue": "Chinese Journal of Clinical Oncology",
        "year": 1998,
        "id": "ryvQOM8O"
    },
    "qlQPef8e": {
        "authors": [
            {
                "name": "Q. Liu",
                "org": ""
            },
            {
                "name": "L. Jiang",
                "org": ""
            },
            {
                "name": "W.-L. Liu",
                "org": ""
            },
            {
                "name": "X.-J. Kang",
                "org": ""
            },
            {
                "name": "Y. Ao",
                "org": ""
            },
            {
                "name": "M. Sun",
                "org": ""
            },
            {
                "name": "Y. Luo",
                "org": ""
            },
            {
                "name": "Y. Song",
                "org": ""
            },
            {
                "name": "W.H.Y. Lo",
                "org": ""
            },
            {
                "name": "X. Zhang",
                "org": ""
            }
        ],
        "title": "Two novel mutations and evidence for haploinsufficiency of the ADAR gene in dyschromatosis symmetrica hereditaria",
        "keywords": [
            "ADAR",
            "Double-stranded RNA-specific adenosine deaminase",
            "Dyschromatosis symmetrica hereditaria",
            "Haploinsufficiency"
        ],
        "venue": "British Journal of Dermatology",
        "year": 2006,
        "id": "qlQPef8e"
    },
    "9aroDwTA": {
        "authors": [
            {
                "name": "L.-H. Cao",
                "org": "Research Center for Medical Genomics"
            },
            {
                "name": "Y. Luo",
                "org": "Research Center for Medical Genomics"
            },
            {
                "name": "W. Wen",
                "org": "Research Center for Medical Genomics"
            },
            {
                "name": "W.-L. Liu",
                "org": "Department of Dermatology"
            },
            {
                "name": "L. Jiang",
                "org": "Research Center for Medical Genomics"
            },
            {
                "name": "C. Chen",
                "org": "Research Center for Medical Genomics"
            },
            {
                "name": "C.-Y. Ji",
                "org": "Research Center for Medical Genomics"
            },
            {
                "name": "X. Zhang",
                "org": "State Key Laboratory of Medical Molecular Biology"
            }
        ],
        "title": "A novel frameshift mutation in keratin 16 underlies pachyonychia congenita with focal palmoplantar keratoderma",
        "abstract": "",
        "keywords": [
            ""
        ],
        "venue": "British Journal of Dermatology",
        "year": 2011,
        "id": "9aroDwTA"
    },
    "AnkIunyI": {
        "authors": [
            {
                "name": "Y. Xu",
                "org": "Department of Breast Surgery, General Surgery"
            },
            {
                "name": "F. Zhao",
                "org": "Department of Surgical Oncology and General Surgery"
            },
            {
                "name": "Z. Wang",
                "org": "Department of Surgical Oncology and General Surgery"
            },
            {
                "name": "Y. Song",
                "org": "Department of Surgical Oncology and General Surgery"
            },
            {
                "name": "Y. Luo",
                "org": "Research Center for Medical Genomics"
            },
            {
                "name": "X. Zhang",
                "org": "Research Center for Medical Genomics"
            },
            {
                "name": "L. Jiang",
                "org": "Research Center for Medical Genomics"
            },
            {
                "name": "Z. Sun",
                "org": "Department of Surgical Oncology and General Surgery"
            },
            {
                "name": "Z. Miao",
                "org": "Department of Surgical Oncology and General Surgery"
            },
            {
                "name": "H. Xu",
                "org": "Department of Surgical Oncology and General Surgery"
            }
        ],
        "title": "MicroRNA-335 acts as a metastasis suppressor in gastric cancer by targeting Bcl-w and specificity protein 1",
        "keywords": [
            ""
        ],
        "venue": "Oncogene",
        "year": 2012,
        "id": "AnkIunyI"
    },
    "MTI3ZWhr": {
        "authors": [
            {
                "name": "X.S. Xing",
                "org": "Research Center for Medical Genomics"
            },
            {
                "name": "H.W. Zhu",
                "org": "McKusick-Zhang Center for Genetic Medicine and State Key Laboratory of Medical Molecular Biology"
            },
            {
                "name": "C. Chen",
                "org": "Research Center for Medical Genomics"
            },
            {
                "name": "S.S. Wang",
                "org": "Research Center for Medical Genomics"
            },
            {
                "name": "Y. Luo",
                "org": "Research Center for Medical Genomics"
            },
            {
                "name": "X. Zhang",
                "org": "McKusick-Zhang Center for Genetic Medicine and State Key Laboratory of Medical Molecular Biology"
            }
        ],
        "title": "Mutation analysis of a Chinese pedigree with triphalangeal thumb-polysyndactyly syndrome",
        "abstract": "Triphalangeal thumb-polysyndactyly syndrome (TPTPS) is an autosomal dominant limb disorder with triphalangeal thumbs, polysyndactyly, and syndactyly. In this study, we describe a four-generation Han Chinese family with eight affected members. Haplotype analysis, Affymetrix SNP 6.0 arrays, qPCR, and gap-PCR were performed. Haplotyping results linked the disease-causing region to the 7q36 region that includes the zone of polarizing activity-regulatory sequence. A 442-kb duplication was found on chromosome 7 that co-segregated with the disease phenotype. The extent of the duplication was determined by qPCR, and the breakpoints were identified by gap-PCR and direct sequencing. This mutation was not detected in normal members in the same family. Our data therefore suggest that this novel microduplication, between 155,913,768 and 156,355,553 bp on chromosome 7, could be considered the cause of TPTPS in this kindred. \u00a9 FUNPEC-RP.",
        "keywords": [
            "Microduplication",
            "TPTPS",
            "Zone of polarizing activity-regulatory sequence"
        ],
        "venue": "Genetics and Molecular Research",
        "year": 2014,
        "id": "MTI3ZWhr"
    },
    "c8cxTOpE": {
        "authors": [
            {
                "name": "J. Sheng",
                "org": ""
            },
            {
                "name": "Y. Luo",
                "org": ""
            },
            {
                "name": "H. Wainwright",
                "org": ""
            }
        ],
        "title": "Studies on lipoxygenase and the formation of ethylene in tomato",
        "abstract": "Lipoxygenase (LAX) activity was assayed in various parts of tomato (Lycopersicon esculentum cv. Caruso) fruits, after harvest and at different stages of ripening. Lipoxygenase activity reached a peak at the turning stage of ripeness in the pericarp and radical pericarp tissue. The changing pattern of C",
        "keywords": [
            ""
        ],
        "venue": "Journal of Horticultural Science and Biotechnology",
        "year": 2000,
        "id": "c8cxTOpE"
    },
    "ZHDfPAVm": {
        "authors": [
            {
                "name": "P.M.A. Toivonen",
                "org": "Agriculture and Agri-Food Canada"
            },
            {
                "name": "C. Lu",
                "org": "Agriculture and Agri-Food Canada"
            },
            {
                "name": "Y. Luo",
                "org": "China Agricultural University"
            }
        ],
        "title": "Total peroxides, lipid soluble antioxidant levels and antioxidant enzyme activities of whole 'spartan' apples during treatment in air, 1 and 100 kPa oxygen and their relation to slice quality",
        "abstract": "Total tissue peroxide levels, lipid soluble antioxidant levels and antioxidant enzyme activities were monitored in 'Spartan' apples during treatment in air (21 kPa oxygen), 1 kPa oxygen and 100 kPa oxygen. Total peroxide levels were lowest and lipid soluble antioxidant levels were highest in apples during treatment under 100 kPa oxygen. The 100 kPa oxygen treatment also resulted in an increase in catalase (CAT) activity and reduced activities of peroxidase (POD), polyphenol oxidase (PPO) and superoxide dismutase (SOD) in crude extracts from whole apples. Slices made from this treatment developed the lowest level of browning and had the best firmness retention as compared with slices made from apples from the other two treatments. Apples held in the air treatment showed lower catalase activity, higher POD and SOD activities and similar PPO activity as compared with the 100 kPa oxygen treated apples. The 1 kPa oxygen treatment resulted in lowest catalase activity, high SOD activity, intermediate POD activity and the low PPO activity compared with the control treatment. A model is presented to relate these responses to effects on deteriorative processes responsible for quality loss in apple slices which were made from treated apples. The hypothesis is that short duration pretreatment with high oxygen induces an antioxidant acclimation in the tissue against active oxygen species thus preventing cellular breakdown after cutting into slices. This results in lower levels of cut surface browning.",
        "keywords": [
            "Antioxidant systems",
            "Browning",
            "Fresh cut",
            "Malus domestica",
            "Membrane integrity",
            "Oxygen"
        ],
        "venue": "Acta Horticulturae",
        "year": 2003,
        "id": "ZHDfPAVm"
    },
    "q9PI4iv7": {
        "authors": [
            {
                "name": "H. Zhang",
                "org": "National Engineering and Technology"
            },
            {
                "name": "S. Wang",
                "org": "National Engineering and Technology"
            },
            {
                "name": "D. Xiu",
                "org": "National Engineering and Technology"
            },
            {
                "name": "Y. Guo",
                "org": "National Engineering and Technology"
            },
            {
                "name": "L. Li",
                "org": "National Engineering and Technology"
            },
            {
                "name": "W. Guan",
                "org": "National Engineering and Technology"
            },
            {
                "name": "Y. Luo",
                "org": "China Agriculture University"
            },
            {
                "name": "Q. Kong",
                "org": "Shenyang Agriculture University"
            }
        ],
        "title": "Studies on the relationship of the microstructure of 'red globe' grape epidermis, enzyme activity and SO2 Damage",
        "abstract": "The epidermis of 'Red Globe' grape was shown to be more sensitive to SO",
        "keywords": [
            "Chloramphenicol acetyltransferase",
            "Epidermis wax",
            "Malondialdehyde",
            "Sensitivity to SO2",
            "Superoxide dismutase"
        ],
        "venue": "Acta Horticulturae",
        "year": 2003,
        "id": "q9PI4iv7"
    },
    "KfzyAJvf": {
        "authors": [
            {
                "name": "X. Li",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "K. Huang",
                "org": "Supervision and Testing Center for GMOs Food Safety"
            },
            {
                "name": "X. He",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "B. Zhu",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Z. Liang",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "H. Li",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Y. Luo",
                "org": "Supervision and Testing Center for GMOs Food Safety"
            }
        ],
        "title": "Comparison of nutritional quality between Chinese indica rice with sck and cry1Ac genes and its nontransgenic counterpart",
        "abstract": "Nutritional assessment of transgenic crops used for human food and animal feed is an important aspect of safety evaluations. An insect-resistant rice (IRR) was generated by the stable insertion of sck, a modified cowpea trypsin inhibitor gene, and cry1Ac, encoding a crystal protein from Bacillus thuringiensis into the genome of a common variety of Chinese indica rice. The composition of the brown and milled rice grain from the resulted IRR line designated Liangyou Kefeng No. 6 was compared with that of the parental rice cultivar Liangyou 2186. Nutrients, including the proximates, amino acids, fatty acids, minerals, and vitamins, were measured. The antinutritive components such as phytic acid, lectin, and trypsin inhibitors were also examined. The data demonstrated that the nutritional quality of both the brown and milled rice grains from the transgenic line was substantially equivalent to that of the nontransgenic counterpart, and measured amounts of nutritional components fell within the range of values reported for other commercial lines. \u00a9 2007 Institute of Food Technologists.",
        "keywords": [
            "Compositional analysis",
            "Food safety",
            "Substantial equivalence",
            "Transgenic rice"
        ],
        "venue": "Journal of Food Science",
        "year": 2007,
        "id": "KfzyAJvf"
    },
    "bwzBjC7L": {
        "authors": [
            {
                "name": "Y. Lu",
                "org": "Supervision, Inspection and Testing Center of Genetically Modified Organisms"
            },
            {
                "name": "W. Xu",
                "org": "Supervision, Inspection and Testing Center of Genetically Modified Organisms"
            },
            {
                "name": "A. Kang",
                "org": "Dept. of Laboratory Animal Science"
            },
            {
                "name": "Y. Luo",
                "org": "Supervision, Inspection and Testing Center of Genetically Modified Organisms"
            },
            {
                "name": "F. Guo",
                "org": "Supervision, Inspection and Testing Center of Genetically Modified Organisms"
            },
            {
                "name": "R. Yang",
                "org": "Supervision, Inspection and Testing Center of Genetically Modified Organisms"
            },
            {
                "name": "J. Zhang",
                "org": "Supervision, Inspection and Testing Center of Genetically Modified Organisms"
            },
            {
                "name": "K. Huang",
                "org": "Supervision, Inspection and Testing Center of Genetically Modified Organisms"
            }
        ],
        "title": "Prokaryotic expression and allergenicity assessment of hygromycin B phosphotransferase protein derived from genetically modified plants",
        "abstract": "The hygromycin B phosphotransferase gene (hpt) has been widely used in the process of plant genetic engineering to produce plants that can secrete the HPT protein. As part of a safety assessment, sufficient quantities of the protein were produced in Escherichia coli to conduct in vitro digestibility and animal studies. Western blotting analysis showed that the HPT protein was digested by simulated gastric fluid within 40 s. ELISA demonstrated that the protein did not induce detectable levels of specific IgE antibodies or histamine in test animals. Alignment of the amino acid sequence of HPT with those of known allergens did not produce evidence of sequence similarities between these allergens and the HPT protein. We conclude that HPT has a low probability to induce allergenicity. \u00a9 2007 Institute of Food Technologists.",
        "keywords": [
            "Allergenicity",
            "Animal model",
            "HPT protein",
            "In vitro digestibility",
            "Safety assessment"
        ],
        "venue": "Journal of Food Science",
        "year": 2007,
        "id": "bwzBjC7L"
    },
    "8vSyme7z": {
        "authors": [
            {
                "name": "X. Li",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "K. Huang",
                "org": "Supervision and Testing Center for GMOs Food Safety"
            },
            {
                "name": "B. Zhu",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Z. Liang",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "L. Wei",
                "org": "College of Food Science and Nutritional Engineering"
            },
            {
                "name": "Y. Luo",
                "org": "Supervision and Testing Center for GMOs Food Safety"
            },
            {
                "name": "Yunbo",
                "org": ""
            }
        ],
        "title": "Comparative physicochemical properties and structure of rice containing the sck + cryIAc genes and its nontransgenic counterpart",
        "abstract": "The physicochemical properties and structure of an insect-resistant rice, Liangyou Kefeng Nr. 6 (IRR), containing the sck and cryIAc genes were compared with those of its nontransgenic counterpart designated as Liangyou 2186 (control), considering their key role in determining commercial value. Basically the appearance of IRR was not affected in terms of size and shape after foreign gene transformation but improved with lower chalkiness. The milling yield of IRR with lower chalkiness was higher measured by head rice yield compared with its parental control. The differences in appearance and milling quality were confirmed by the structure of raw rice grain by scanning electron microscopy (SEM). Slight differences were observed in pasting properties and textural quality determined by rapid viscosity analyzer and texture analyzer which was in agreement with the result of the structure of cooked rice grain by SEM. The above differences might be as a result of a positional effect of T-DNA insertion. On the whole, the appearance, milling quality, and eating quality of IRR were not adversely affected by transgenes, which will facilitate its acceptance by the consumer after commercialization. \u00a9 2007 Institute of Food Technologists.",
        "keywords": [
            "Physicochemical properties",
            "Structure",
            "Transgenic rice"
        ],
        "venue": "Journal of Food Science",
        "year": 2008,
        "id": "8vSyme7z"
    },
    "FHQnJxHb": {
        "authors": [
            {
                "name": "Y. Shao",
                "org": ""
            },
            {
                "name": "Y. Luo",
                "org": ""
            },
            {
                "name": "A. Chen",
                "org": ""
            },
            {
                "name": "H. Chu",
                "org": ""
            },
            {
                "name": "C. Lu",
                "org": ""
            },
            {
                "name": "Y. Zhu",
                "org": ""
            },
            {
                "name": "H. Tian",
                "org": ""
            },
            {
                "name": "B. Zhu",
                "org": ""
            }
        ],
        "title": "Effects of a vacuum infiltration-Based method with ascorbic acid on internal browning of plum (Prunus salicina Lindell cv. Yuhuang) during cold storage",
        "keywords": [
            ""
        ],
        "venue": "Journal of Food Processing and Preservation",
        "year": 2011,
        "id": "FHQnJxHb"
    },
    "DmMmACzM": {
        "authors": [
            {
                "name": "H. Shi",
                "org": "Laboratory of Food Safety"
            },
            {
                "name": "W. Xu",
                "org": "Supervision and Testing Center of Agricultural Products Quality"
            },
            {
                "name": "Y. Luo",
                "org": "Supervision and Testing Center of Agricultural Products Quality"
            },
            {
                "name": "L. Chen",
                "org": "Laboratory of Food Safety"
            },
            {
                "name": "Z. Liang",
                "org": "Supervision and Testing Center of Agricultural Products Quality"
            },
            {
                "name": "X. Zhou",
                "org": "Supervision and Testing Center of Agricultural Products Quality"
            },
            {
                "name": "K. Huang",
                "org": "Supervision and Testing Center of Agricultural Products Quality"
            }
        ],
        "title": "The effect of various environmental factors on the ethidium monazite and quantitative PCR method to detect viable bacteria",
        "abstract": "Aims: Ethidium monoazide in combination with quantitative PCR (EMA-qPCR) has been considered as a promising method to enumerate viable cells; however, its efficacy can be significantly affected by disinfection conditions and various environments. In this study, thermal disinfection, osmotic pressure and acids with different pH values were systematically investigated to achieve the optimum conditions. Methods and Results: EMA treatment of pure cultures at low concentration (10\u03bcgml ",
        "keywords": [
            "Cell viability",
            "Environmental factors",
            "Escherichia coli",
            "Ethidium monoazide",
            "Quantitative PCR"
        ],
        "venue": "Journal of Applied Microbiology",
        "year": 2011,
        "id": "DmMmACzM"
    },
    "2wZ37Ngb": {
        "authors": [
            {
                "name": "Y. Luo",
                "org": "Zhongshan Ophthalmic Center"
            },
            {
                "name": "S. Tang",
                "org": "Zhongshan Ophthalmic Center"
            },
            {
                "name": "S. Lin",
                "org": "Zhongshan Ophthalmic Center"
            }
        ],
        "title": "A study on the purification of retinal photoreceptors",
        "abstract": "Objective: To investigate methods for isolation of the pure retinal photoreceptors. Methods: Modified excimer laser surgery, regular excimer laser surgery, and enzyme gradation digestion were used to isolate retinal photoreceptors. The resulting retinal tissues were stained with hematoxylin- eosin (HE). Results: The retinal sheets obtained by these three methods each demonstrated a layer of pure photoreceptors by HE staining. Modified and regular excimer laser surgery could both precisely ablate retina. Modified excimer laser ablation obtained photoreceptor sheets with perfect inner and outer segment, while regular excimer laser ablation got photoreceptor sheets with impaired inner and outer segment. Enzyme gradation digestion could also result in photoreceptor sheets with good inner and outer segments, although there was non-precise digestion. Conclusion: Modified excimer laser surgery and enzyme gradation digestion can be used to obtain a layer of pure photoreceptors with good tissue preservation; specially perfect inner and outer segment. These cells may be a source for retinal transplantation.",
        "keywords": [
            "Enzyme digestion",
            "Laser surgery",
            "Pure photoreceptors",
            "Retinal transplantation"
        ],
        "venue": "Chinese Ophthalmic Research",
        "year": 2000,
        "id": "2wZ37Ngb"
    },
    "2bbwiVEc": {
        "authors": [
            {
                "name": "Y. Luo",
                "org": ""
            },
            {
                "name": "C.X. Yuan",
                "org": ""
            },
            {
                "name": "Y.L. Peng",
                "org": ""
            },
            {
                "name": "P.L. Wei",
                "org": ""
            },
            {
                "name": "Z.D. Zhang",
                "org": ""
            },
            {
                "name": "J.M. Jiang",
                "org": ""
            },
            {
                "name": "L. Dai",
                "org": ""
            },
            {
                "name": "Y.K. Hu",
                "org": ""
            }
        ],
        "title": "Can ultrasound predict the severity of acute pancreatitis early by observing acute fluid collection?",
        "abstract": "",
        "keywords": [
            ""
        ],
        "venue": "World Journal of Gastroenterology",
        "year": 2001,
        "id": "2bbwiVEc"
    },
    "4CmRo2re": {
        "authors": [
            {
                "name": "Xingwu Ran",
                "org": ""
            },
            {
                "name": "C. Wang",
                "org": ""
            },
            {
                "name": "H. Wang",
                "org": ""
            },
            {
                "name": "T. Zhao",
                "org": ""
            },
            {
                "name": "N. Tong",
                "org": ""
            },
            {
                "name": "B. Song",
                "org": ""
            },
            {
                "name": "H. Bu",
                "org": ""
            },
            {
                "name": "Y. Luo",
                "org": ""
            },
            {
                "name": "H. Tian",
                "org": ""
            },
            {
                "name": "X. Li",
                "org": ""
            }
        ],
        "title": "Muscle infarction involving muscles of abdominal and thoracic walls in diabetes",
        "abstract": "Aims: This paper presents two cases of muscle infarction involving four major muscles of the anterior abdominal wall (case 1) and pectoralis major (case 2) in individuals with diabetes. Methods: Erythrocyte sedimentation rate (ESR) and creatine kinase (CK) were measured and Doppler ultrasound, an open muscle biopsy (case 1) and magnetic resonance imaging (MRI) (case 2) were performed. Result: The diagnosis of muscle infarction was made by histological findings and MRI images with hyper-intensive signals on a gadolinium-enhanced T ",
        "keywords": [
            "Diabetes mellitus",
            "Diagnosis",
            "Muscle infarction",
            "Treatment"
        ],
        "venue": "Diabetic Medicine",
        "year": 2005,
        "id": "4CmRo2re"
    },
    "o3vpZtHw": {
        "authors": [
            {
                "name": "Z.L. Wang",
                "org": "Graduate School of the Chinese Academy of Sciences"
            },
            {
                "name": "Z.W. Quan",
                "org": "Graduate School of the Chinese Academy of Sciences"
            },
            {
                "name": "P.Y. Jia",
                "org": "Graduate School of the Chinese Academy of Sciences"
            },
            {
                "name": "C.K. Lin",
                "org": "Graduate School of the Chinese Academy of Sciences"
            },
            {
                "name": "Y. Luo",
                "org": "Graduate School of the Chinese Academy of Sciences"
            },
            {
                "name": "Y. Chen",
                "org": "Advanced Materials Reseach Institute"
            },
            {
                "name": "J. Fang",
                "org": "Advanced Materials Reseach Institute"
            },
            {
                "name": "W. Zhou",
                "org": "Advanced Materials Reseach Institute"
            },
            {
                "name": "C.J. O'Connor",
                "org": "Advanced Materials Reseach Institute"
            },
            {
                "name": "J. Lin",
                "org": "Graduate School of the Chinese Academy of Sciences"
            }
        ],
        "title": "A facile synthesis and photoluminescent properties of redispersible CeF 3, CeF 3:Tb 3+, and CeF 3:Tb 3+/LaF 3 (core/shell) nanoparticles",
        "abstract": "CeF ",
        "keywords": [
            ""
        ],
        "venue": "Chemistry of Materials",
        "year": 2006,
        "id": "o3vpZtHw"
    },
    "kxeqTNJK": {
        "authors": [
            {
                "name": "P.Y. Jia",
                "org": ""
            },
            {
                "name": "X.M. Liu",
                "org": ""
            },
            {
                "name": "M. Yu",
                "org": ""
            },
            {
                "name": "Y. Luo",
                "org": ""
            },
            {
                "name": "J. Fang",
                "org": ""
            },
            {
                "name": "J. Lin",
                "org": ""
            }
        ],
        "title": "Luminescence properties of sol-gel derived spherical SiO2@Gd2(WO4)3:Eu3+ particles with core-shell structure",
        "abstract": "Monodisperse, core-shell structured SiO",
        "keywords": [
            ""
        ],
        "venue": "Chemical Physics Letters",
        "year": 2006,
        "id": "kxeqTNJK"
    },
    "jzVQMzUd": {
        "authors": [
            {
                "name": "Z.-Y. Ding",
                "org": "Department of Oncology"
            },
            {
                "name": "Y. Wu",
                "org": "Department of Oncology"
            },
            {
                "name": "Y. Luo",
                "org": "Department of Oncology"
            },
            {
                "name": "J.-M. Su",
                "org": "Department of Oncology"
            },
            {
                "name": "Q. Li",
                "org": "Department of Oncology"
            },
            {
                "name": "X.-W. Zhang",
                "org": "Department of Oncology"
            },
            {
                "name": "J.-Y. Liu",
                "org": "Department of Oncology"
            },
            {
                "name": "Q.-M. He",
                "org": "Department of Oncology"
            },
            {
                "name": "L. Yang",
                "org": "Department of Oncology"
            },
            {
                "name": "L. Tian",
                "org": "Department of Oncology"
            },
            {
                "name": "X. Zhao",
                "org": "Department of Oncology"
            },
            {
                "name": "H.-X. Deng",
                "org": "Department of Oncology"
            },
            {
                "name": "Y.-J. Wen",
                "org": "Department of Oncology"
            },
            {
                "name": "J. Li",
                "org": "Department of Oncology"
            },
            {
                "name": "B. Kang",
                "org": "Department of Oncology"
            },
            {
                "name": "Y.-Q. Wei",
                "org": "Department of Oncology"
            }
        ],
        "title": "Mannan-modified adenovirus as a vaccine to induce antitumor immunity",
        "abstract": "Tumor vaccine is a useful strategy for cancer therapy. However, priming of the immune system requires the relevant antigen to be presented by antigen-presenting cells (APCs). Here, we employed telomerase reverse transcriptase as a model antigen to explore the feasibility of using mannan-modified adenovirus as a tumor vaccine. We found that tumor immunogene therapy with the vaccine was effective at protective antitumor immunity in mice. The antigen-specific cytotoxic T lymphocytes were found in in vitro cytotoxicity assay. The elevation of the killing activity could be abrogated by anti-CD8 or anti-major histocompatibility complex-I antibodies. Adoptive transfer of purified CD8",
        "keywords": [
            ""
        ],
        "venue": "Gene Therapy",
        "year": 2007,
        "id": "jzVQMzUd"
    },
    "Ssc63KOE": {
        "authors": [
            {
                "name": "X. Li",
                "org": ""
            },
            {
                "name": "Y. Luo",
                "org": ""
            },
            {
                "name": "L. Yu",
                "org": ""
            },
            {
                "name": "Y. Lin",
                "org": ""
            },
            {
                "name": "D. Luo",
                "org": ""
            },
            {
                "name": "H. Zhang",
                "org": ""
            },
            {
                "name": "Y. He",
                "org": ""
            },
            {
                "name": "Y.-O. Kim",
                "org": ""
            },
            {
                "name": "Y. Kim",
                "org": ""
            },
            {
                "name": "S. Tang",
                "org": ""
            },
            {
                "name": "W. Min",
                "org": ""
            }
        ],
        "title": "SENP1 mediates TNF-induced desumoylation and cytoplasmic translocation of HIPK1 to enhance ASK1-dependent apoptosis",
        "keywords": [
            ""
        ],
        "venue": "Cell Death and Differentiation",
        "year": 2008,
        "id": "Ssc63KOE"
    },
    "Zb0O4soj": {
        "authors": [
            {
                "name": "M. Hu",
                "org": "The Central Laboratory"
            },
            {
                "name": "J.-L. Yang",
                "org": "State Key Laboratory of Biotherapy"
            },
            {
                "name": "Y.-Q. Jia",
                "org": "Department of Respiratory Medicine"
            },
            {
                "name": "R. Wang",
                "org": "State Key Laboratory of Biotherapy"
            },
            {
                "name": "X.-W. Zhang",
                "org": "State Key Laboratory of Biotherapy"
            },
            {
                "name": "Y. Wu",
                "org": "State Key Laboratory of Biotherapy"
            },
            {
                "name": "Y. Luo",
                "org": "State Key Laboratory of Biotherapy"
            },
            {
                "name": "X.-C. Chen",
                "org": "State Key Laboratory of Biotherapy"
            },
            {
                "name": "R. Zhang",
                "org": "State Key Laboratory of Biotherapy"
            },
            {
                "name": "L. Tian",
                "org": "State Key Laboratory of Biotherapy"
            },
            {
                "name": "X. Zhao",
                "org": "State Key Laboratory of Biotherapy"
            },
            {
                "name": "Y.-Q. Wei",
                "org": "State Key Laboratory of Biotherapy"
            }
        ],
        "title": "Anti-angiogenesis therapy based on the bone marrow-derived stromal cells genetically engineered to express sFlt-1 in mouse tumor model",
        "keywords": [
            ""
        ],
        "venue": "BMC Cancer",
        "year": 2008,
        "id": "Zb0O4soj"
    },
    "udC9SED6": {
        "authors": [
            {
                "name": "S. Su",
                "org": ""
            },
            {
                "name": "Y. Li",
                "org": ""
            },
            {
                "name": "Y. Luo",
                "org": ""
            },
            {
                "name": "Y. Sheng",
                "org": ""
            },
            {
                "name": "Y. Su",
                "org": ""
            },
            {
                "name": "R.N. Padia",
                "org": ""
            },
            {
                "name": "Z.K. Pan",
                "org": ""
            },
            {
                "name": "Z. Dong",
                "org": ""
            },
            {
                "name": "S. Huang",
                "org": ""
            }
        ],
        "title": "Proteinase-activated receptor 2 expression in breast cancer and its role in breast cancer cell migration",
        "abstract": "Proteinase-activated receptor 2 (PAR2) is a G protein-coupled receptor that is activated by trypsin-like proteinases. PAR2 is detected in breast tumor specimens; however, it is not clear how PAR2 level in breast cancer cell/tissues compares with normal cell/tissues. Here, we show the elevation of PAR2 protein level in 76 of 105 breast tumor specimens but only 5 of 24 normal breast tissues. PAR2 level is also higher in breast cancer cell lines than that in normal breast cells and non-cancerous breast cell lines. To determine the role of PAR2 in breast carcinogenesis, we examined the effect of PAR2 agonists on cell proliferation and migration. Our studies show that PAR2 agonists (PAR2-activating peptide and trypsin) are neither potent growth enhancers nor chemoattractants to breast cancer cells. Instead, PAR2 agonists induce significant chemokinesis. PAR2-mediated chemokinesis is G",
        "keywords": [
            "Breast cancer",
            "Chemokinesis",
            "JNK",
            "PAR2",
            "Paxillin",
            "Src"
        ],
        "venue": "Oncogene",
        "year": 2009,
        "id": "udC9SED6"
    },
    "e6OQxPGd": {
        "authors": [
            {
                "name": "T. Huang",
                "org": "State Key Laboratory of Ophthalmology"
            },
            {
                "name": "Y. Wang",
                "org": "State Key Laboratory of Ophthalmology"
            },
            {
                "name": "A. Hu",
                "org": "State Key Laboratory of Ophthalmology"
            },
            {
                "name": "Y. Luo",
                "org": "State Key Laboratory of Ophthalmology"
            },
            {
                "name": "J. Chen",
                "org": "State Key Laboratory of Ophthalmology"
            }
        ],
        "title": "Use of paediatric donor tissue in Descemet stripping endothelial keratoplasty",
        "abstract": "Aims: To evaluate the feasibility, efficacy and postoperative complications of Descemet stripping endothelial keratoplasty (DSEK) with paediatric donor tissue. Methods: Retrospective non-comparative interventional case series. Seven consecutive cases (seven eyes) of pseudophakic bullous keratopathy were treated with DSEK using paediatric donor tissue and followed up for 12 to 18 months. Data collected included best spectacle-corrected visual acuity, spherical equivalent refractive error, corneal astigmatism, corneal curvature and endothelial cell density. Results: DSEK was successfully performed in six out of seven eyes with paediatric donor graft; one paediatric donor graft perforated during dissection. All paediatric tissue was unfolded using the \"hitch suture\" technique and supported with plenty of air. No graft dislocation occurred. At 12 months postoperatively, the cornea was clear in all eyes; the best spectacle-corrected visual acuity ranged from 20/67 to 20/32; the average spherical equivalent refractive error was 1.9 (0.5) dioptres; the average corneal astigmatism was 2.2 (0.6) dioptres; the average corneal curvature was 45.2 (1.6) dioptres; and the average endothelial cell density was 2247.7 (74.3) cells/mm2 (41.4 (3.7)% of endothelial cell loss). Conclusion: With high postoperative endothelial cell counts, low graft dislocation rate and absence of high myopic shifts, paediatric donor tissue can be successfully used in DSEK.",
        "keywords": [
            ""
        ],
        "venue": "British Journal of Ophthalmology",
        "year": 2009,
        "id": "e6OQxPGd"
    },
    "7K0U8p4f": {
        "authors": [
            {
                "name": "S. Jin",
                "org": "Department of Liver and Vascular Surgery"
            },
            {
                "name": "L. Yan",
                "org": "Department of Liver and Vascular Surgery"
            },
            {
                "name": "B. Li",
                "org": "Department of Liver and Vascular Surgery"
            },
            {
                "name": "T. Wen",
                "org": "Department of Liver and Vascular Surgery"
            },
            {
                "name": "J. Zhao",
                "org": "Department of Liver and Vascular Surgery"
            },
            {
                "name": "Y. Zeng",
                "org": "Department of Hepato-bilio-pancreatic Surgery"
            },
            {
                "name": "Z. Chen",
                "org": "Department of Hepato-bilio-pancreatic Surgery"
            },
            {
                "name": "W. Wang",
                "org": "Department of Liver and Vascular Surgery"
            },
            {
                "name": "M. Xu",
                "org": "Department of Liver and Vascular Surgery"
            },
            {
                "name": "J. Yang",
                "org": "Department of Liver and Vascular Surgery"
            },
            {
                "name": "Y. Luo",
                "org": "Department of Liver and Vascular Surgery"
            },
            {
                "name": "H. Wu",
                "org": "Department of Hepato-bilio-pancreatic Surgery"
            }
        ],
        "title": "Quality of life and psychologic distress of recipients after adult living-donor liver transplantation (LDLT)-a study from mainland china",
        "abstract": "This cross-sectional study investigated potential factors impacting quality of life in 125 recipients after living-donor liver transplantation (LDLT). Health-related quality of life (HRQoL) was measured by using the Chinese version of Medical Outcomes Study Short Form36 (SF-36), and psychologic symptoms by using the Symptom Checklist90Revised (SCL-90-R). Clinical and demographic data were collected from the records of the Chinese Liver Transplant Registry and via questionnaire. A total of 102 recipients (81.6%) completed the questionnaires. All SF-36 domain scores (except the mental health score) were lower in the study than in the general population of Sichuan. The mental quality of life was significantly lower in female than in male subjects (P = .000). Regarding the role-physical (P = .016), social functioning (P = .000), and role-emotional (P = .004) domains, recipients >1 year after transplantation scored higher than those <1 year. Bodily pain scores were lower in recipients with prior acute liver failure than those with hepatic carcinoma or hepatic cirrhosis (P = .032). Social functioning was poorer in recipients with than in those without complications (P = .039). Mental component summary scale (MCS) scores and some of physical component summary scale (PCS) significantly correlated with symptom dimension scores of the SCL-90-R (P < .05). In conclusion, gender, time since transplant, etiology of disease, complications, occupation, and some psychologic symptoms were possible factors influencing postoperative HRQoL of LDLT recipients. \u00a9 2010 by Elsevier Inc. All rights reserved.",
        "keywords": [
            ""
        ],
        "venue": "Transplantation Proceedings",
        "year": 2010,
        "id": "7K0U8p4f"
    },
    "tt4SitWj": {
        "authors": [
            {
                "name": "Y. Luo",
                "org": ""
            },
            {
                "name": "H. Zhou",
                "org": ""
            },
            {
                "name": "L. Liu",
                "org": ""
            },
            {
                "name": "T. Shen",
                "org": ""
            },
            {
                "name": "W. Chen",
                "org": ""
            },
            {
                "name": "B. Xu",
                "org": ""
            },
            {
                "name": "X. Han",
                "org": ""
            },
            {
                "name": "F. Zhang",
                "org": ""
            },
            {
                "name": "R.S. Scott",
                "org": ""
            },
            {
                "name": "J.S. Alexander",
                "org": ""
            },
            {
                "name": "A. Alam",
                "org": ""
            },
            {
                "name": "S. Huang",
                "org": ""
            }
        ],
        "title": "The fungicide ciclopirox inhibits lymphatic endothelial cell tube formation by suppressing VEGFR-3-mediated ERK signaling pathway",
        "abstract": "Ciclopirox olamine (CPX), an off-patent antifungal agent used to treat mycoses of skin and nails, has recently been demonstrated to be a potential anticancer agent. However, the underlying mechanism is not well understood. Here, for the first time, we show that CPX inhibited lymphangiogenesis in an in vitro model (tube formation). This effect was, in part, associated with inhibition of vascular endothelial growth factor receptor-3 (VEGFR-3) expression, as overexpression of VEGFR-3 conferred partial resistance to CPX inhibitory effect on tube formation in lymphatic endothelial cells (LECs), whereas downregulation of VEGFR-3 mimicked the effect of CPX, blocking the tube formation. Further study revealed that CPX did not alter mRNA level, but inhibited protein synthesis and promoted protein degradation of VEGFR-3. In addition, we found that CPX inhibited phosphorylation of the extracellular signal-related kinase 1/2 (ERK1/2), a downstream effector of VEGFR-3. Overexpression of VEGFR-3 attenuated CPX inhibition of ERK1/2 phosphorylation, whereas downregulation of VEGFR-3 inhibited ERK1/2 phosphorylation in LECs. Ectopic expression of constitutively active mitogen-activated protein kinase kinase 1 (MKK1) resulted in activation of ERK1/2 and partially prevented CPX inhibition of LEC tube formation. The results suggest that CPX inhibits LEC tube formation at least, in part, through inhibiting VEGFR-3-mediated ERK signaling pathway. \u00a9 2011 Macmillan Publishers Limited All rights reserved.",
        "keywords": [
            "ciclopirox",
            "ERK",
            "lymphatic endothelial cells",
            "tube formation",
            "VEGFR-3"
        ],
        "venue": "Oncogene",
        "year": 2011,
        "id": "tt4SitWj"
    },
    "MsbHOYdM": {
        "authors": [
            {
                "name": "J. Qi",
                "org": "College of Pharmaceutical Sciences"
            },
            {
                "name": "Y. Luo",
                "org": "College of Pharmaceutical Sciences"
            },
            {
                "name": "L. Gao",
                "org": "College of Pharmaceutical Sciences"
            }
        ],
        "title": "Structural diversity of neuritogenic substances and their application perspective",
        "abstract": "Small molecular weight substances are functional, as neurotrophic factors can be developed as therapeutic drugs to treat neurodegenerative disorder. Recently, a large number of natural and synthetic neuritogenic compounds have been discovered. These compounds have various structural features, including terpenoids, lipids, alkaloids, steroid glycosides, small molecular peptides, and so on. Some of them possess not only neurotrophic properties but also neuroprotective activities. The structure-activity relationships (SARs) and mechanism of action of some important compounds have been studied intensively. Increasing experimental evidence suggests that several of these compounds can be promising candidates for drug development. \u00a9 2011 Bentham Science Publishers Ltd.",
        "keywords": [
            "Alzheimer's disease",
            "Natural products",
            "Nerve growth factor",
            "Neuritogenic substances",
            "Neuronal cells",
            "Neurotrophic factors"
        ],
        "venue": "Mini-Reviews in Medicinal Chemistry",
        "year": 2011,
        "id": "MsbHOYdM"
    },
    "9r2rFHMH": {
        "authors": [
            {
                "name": "W.-Y. Wang",
                "org": "Department of Anesthesiology"
            },
            {
                "name": "H. Wang",
                "org": "Department of Anesthesiology"
            },
            {
                "name": "Y. Luo",
                "org": "Department of Anesthesiology"
            },
            {
                "name": "L.-J. Jia",
                "org": "Department of Anesthesiology"
            },
            {
                "name": "J.-N. Zhao",
                "org": "Department of Anesthesiology"
            },
            {
                "name": "H.-H. Zhang",
                "org": "Department of Anesthesiology"
            },
            {
                "name": "Z.-W. Ma",
                "org": "Department of Neurobiology"
            },
            {
                "name": "Q.-S. Xue",
                "org": "Department of Anesthesiology"
            },
            {
                "name": "B.-W. Yu",
                "org": "Department of Anesthesiology"
            }
        ],
        "title": "The effects of metabotropic glutamate receptor 7 allosteric agonist N,N'-dibenzhydrylethane-1,2-diamine dihydrochloride on developmental sevoflurane neurotoxicity: Role of extracellular signal-regulated kinase 1 and 2 mitogen-activated protein kinase signaling pathway",
        "abstract": "The present study was designed to evaluate the possible neuroprotective effects of metabotropic glutamate receptor (mGluR7) allosteric agonist . N,. N'-dibenzhydrylethane-1,2-diamine dihydrochloride (AMN082) on developmental sevoflurane neurotoxicity. To achieve the objective, hippocampal cultures (7 DIV, 7 day . in vitro) were treated with different doses of . l-(+)-2-Amino-4-phosphonobutyric acid (l-AP4, an agonist of group III mGluRs), (RS)-\u03b1-Methylserine-O-phosphate (MSOP, an antagonist of group III mGluRs), AMN082 or . cis-2-[[(3,5-Dichlorophenyl)amino]carbonyl]cyclohexanecarboxylic acid (VU0155041, an agonist of mGluR4) before exposed to sevoflurane. Cell apoptosis were determined by flow cytometry and terminal deoxynucleotidyl transferase-mediated dUTP nick-end-labeling (TUNEL)-staining. For . in vivo study, rat pups (7 PND, 7 postnatal day) were injected with AMN082, . l-AP4 or saline before sevoflurane exposure. Extracellular signal-regulated kinase 1 and 2 (ERK1/2), c-Jun N-terminal kinase (JNK), p38, caspase-3, Bcl-2, and Bax were detected by Western blot. The locomotor activity and cognitive functions were evaluated by open-field test and Morris water maze (MWM), respectively. We found that . l-AP4 prevented sevoflurane-induced cell apoptosis, but MSOP promoted. Specially, application of AMN082 contributed to the relief of sevoflurane-induced apoptosis . in vitro, whereas VU0155041 did not. In addition, sevoflurane treatment led to a decrease of Bcl-2 and an increase of caspase-3 and Bax, which were mitigated by AMNO82 . in vivo. Moreover, we showed that sevoflurane treatment resulted in a remarkable suppression of phospho-ERK1/2, which was restored by AMN082. Application of U0126 (an inhibitor of MEK) abolished the neuroprotective effects of AMN082 on sevoflurane neurotoxicity both . in vitro and . in vivo. In addition, sevoflurane exposure also led to an increase of phospho-JNK, but SP600125 (an inhibitor of JNK) did not attenuate sevoflurane-induced apoptosis. The total and phosphorylated p38 remained unchanged in sevoflurane-treated rat pups. Finally, AMN082 improved the learning and memory defects caused by postnatal sevoflurane exposure without alternations in emotion or locomotor activity. These preliminary data indicate that AMN082 may protect immature brain against sevoflurane neurotoxicity, and the ERK1/2 MAP kinase signaling is likely to be involved. Further studies are needed to fully assess the neuroprotective role of mGluR7 agonist AMN082 in developmental anesthetic neurotoxicity. \u00a9 2012 IBRO.",
        "keywords": [
            "Hippocampus",
            "Learning and memory",
            "MAPK",
            "MGluRs",
            "Neurotoxicity",
            "Sevoflurane"
        ],
        "venue": "Neuroscience",
        "year": 2012,
        "id": "9r2rFHMH"
    },
    "MVsAhcqW": {
        "authors": [
            {
                "name": "L. Qiu",
                "org": "Regenerative Medicine Research Center"
            },
            {
                "name": "L. Zhang",
                "org": "Department of Ultrasound"
            },
            {
                "name": "L. Wang",
                "org": "Department of Ultrasound"
            },
            {
                "name": "Y. Jiang",
                "org": "Department of Pathology"
            },
            {
                "name": "Y. Luo",
                "org": "Department of Ultrasound"
            },
            {
                "name": "Y. Peng",
                "org": "Department of Ultrasound"
            },
            {
                "name": "L. Lin",
                "org": "Department of Ultrasound"
            }
        ],
        "title": "Ultrasound-targeted microbubble destruction enhances naked plasmid DNA transfection in rabbit Achilles tendons in vivo",
        "abstract": "The study was to investigate the probability of increasing the transfection of the gene in tendons by ultrasound-targeted microbubble destruction (UTMD), and to search for the most suitable transfection conditions. A mixture of microbubbles and enhanced green fluorescent protein (EGFP) plasmids was injected into rabbit Achilles tendons by different administration routes and the tendons were ultrasound pulse by different ultrasonic conditions in order to determine the most appropriate conditions. Then, the rabbits were divided into four groups: (1) ultrasound + microbubbles + plasmid; (2) ultrasound + plasmid; (3) microbubble + plasmid; (4) plasmid only. EGFP expression in the tendons and other tissues, and the damage to tendon and paratenon were all observed. The results showed that EGFP expression in the tendon was higher by ultrasound pulse with 2W cm",
        "keywords": [
            "gene transfection",
            "microbubble",
            "naked plasmid DNA",
            "tendon",
            "ultrasound"
        ],
        "venue": "Gene Therapy",
        "year": 2012,
        "id": "MVsAhcqW"
    },
    "ahUkG8fT": {
        "authors": [
            {
                "name": "J. Huang",
                "org": "State Key Laboratory of Ophthalmology"
            },
            {
                "name": "X. Li",
                "org": "Department of Hepatobiliary Surgery"
            },
            {
                "name": "M. Li",
                "org": "State Key Laboratory of Ophthalmology"
            },
            {
                "name": "S. Li",
                "org": "State Key Laboratory of Ophthalmology"
            },
            {
                "name": "W. Xiao",
                "org": "State Key Laboratory of Ophthalmology"
            },
            {
                "name": "X. Chen",
                "org": "State Key Laboratory of Ophthalmology"
            },
            {
                "name": "M. Cai",
                "org": "State Key Laboratory of Ophthalmology"
            },
            {
                "name": "Q. Wu",
                "org": "Department of Clinical Research"
            },
            {
                "name": "D. Luo",
                "org": "Department of Clinical Research"
            },
            {
                "name": "S. Tang",
                "org": "State Key Laboratory of Ophthalmology"
            },
            {
                "name": "Y. Luo",
                "org": "State Key Laboratory of Ophthalmology"
            }
        ],
        "title": "Effects of intravitreal injection of KH902, a vascular endothelial growth factor receptor decoy, on the retinas of streptozotocin-induced diabetic rats",
        "keywords": [
            "Diabetic retinopathy",
            "Inner blood retinal barrier",
            "KH902",
            "Placental growth factor",
            "Retinal electrophysiological function",
            "Vascular endothelial growth factor"
        ],
        "venue": "Diabetes, Obesity and Metabolism",
        "year": 2012,
        "id": "ahUkG8fT"
    },
    "gwOLn8N7": {
        "authors": [
            {
                "name": "L.X. Yang",
                "org": "High Level Laboratory of Jiangxi Province for Persistent Pollutants Control"
            },
            {
                "name": "Y.B. Ding",
                "org": "High Level Laboratory of Jiangxi Province for Persistent Pollutants Control"
            },
            {
                "name": "S.L. Luo",
                "org": "State Key Laboroator of Chemo/Biosensing and Chemometrics"
            },
            {
                "name": "Y. Luo",
                "org": "High Level Laboratory of Jiangxi Province for Persistent Pollutants Control"
            },
            {
                "name": "F. Deng",
                "org": "High Level Laboratory of Jiangxi Province for Persistent Pollutants Control"
            },
            {
                "name": "Y. Li",
                "org": "State Key Laboroator of Chemo/Biosensing and Chemometrics"
            }
        ],
        "title": "Fast growth with crystal splitting of morphology-controllable Bi 2S3 flowers on TiO2 nanotube arrays",
        "abstract": "Bi",
        "keywords": [
            ""
        ],
        "venue": "Semiconductor Science and Technology",
        "year": 2013,
        "id": "gwOLn8N7"
    },
    "dbyw23gq": {
        "authors": [
            {
                "name": "X. Chen",
                "org": "State Key Laboratory of Ophthalmology"
            },
            {
                "name": "J. Li",
                "org": "Department of Ophthalmology"
            },
            {
                "name": "M. Li",
                "org": "State Key Laboratory of Ophthalmology"
            },
            {
                "name": "M. Zeng",
                "org": "State Key Laboratory of Ophthalmology"
            },
            {
                "name": "T. Li",
                "org": "State Key Laboratory of Ophthalmology"
            },
            {
                "name": "W. Xiao",
                "org": "State Key Laboratory of Ophthalmology"
            },
            {
                "name": "J. Li",
                "org": "State Key Laboratory of Ophthalmology"
            },
            {
                "name": "Q. Wu",
                "org": "Chengdu Kanghong Biotechnology Co. Ltd"
            },
            {
                "name": "X. Ke",
                "org": "Chengdu Kanghong Biotechnology Co. Ltd"
            },
            {
                "name": "D. Luo",
                "org": "Chengdu Kanghong Biotechnology Co. Ltd"
            },
            {
                "name": "S. Tang",
                "org": "State Key Laboratory of Ophthalmology"
            },
            {
                "name": "Y. Luo",
                "org": "State Key Laboratory of Ophthalmology"
            }
        ],
        "title": "KH902 suppresses high glucose-induced migration and sprouting of human retinal endothelial cells by blocking VEGF and PIGF",
        "abstract": "Aims: Vascular endothelial growth factor (VEGF) and placental growth factor (PlGF) are upregulated in many ocular neovascular diseases such as diabetic retinopathy (DR). KH902 is a recombinant fusion protein with its binding ligand taken from the domains of VEGF receptor-1 (VEGFR-1) and VEGF receptor-2 (VEGFR-2) and can bind all VEGF-A isoforms and PlGF. The aim of this study was to investigate the underlying mechanisms of anti-angiogenic effects of KH902. Methods: The toxic effect of KH902 on cultured human retinal endothelial cells (HRECs) was measured by Annexin V/PI staining and MTT assay. The concentrations of secreted VEGF and PlGF were measured by ELISA. The migration of HRECs was assessed by scratch wound and transwell assay. The sprouting of HRECs was determined by tube formation assay. The protein levels of Src, p-Src, PI3K, Akt1, p-Akt1, Erk1/2 and p-Erk1/2 were measured by Western blot. Results: KH902 at the concentrations from 100ng/ml to 100\u03bcg/ml had no cytotoxicity to cultured HRECs. KH902 bound not only VEGF165, but also PlGF that were secreted by HRECs under high glucose condition. A 500ng/ml of KH902 significantly suppressed high glucose-induced migration and sprouting of HRECs through downregulating the expression of PI3K and inhibiting the activation of Src, Akt1 and Erk1/2. Conclusion: Our study indicates that KH902 suppresses high glucose-induced migration and sprouting of HRECs through not only binding VEGF, but also PlGF to inhibit the activation of Src-Akt1-Erk1/2 pathway. KH902 is a drug that potentially inhibits angiogenic pathways involving in DR or other ocular neovascular diseases. \u00a9 2012 Blackwell Publishing Ltd.",
        "keywords": [
            "High glucose",
            "Human retinal endothelial cells",
            "KH902",
            "Migration",
            "PlGF",
            "Sprouting",
            "VEGF"
        ],
        "venue": "Diabetes, Obesity and Metabolism",
        "year": 2013,
        "id": "dbyw23gq"
    },
    "35w4SbWG": {
        "authors": [
            {
                "name": "H. Tang",
                "org": "School of Chemical Engineering and Technology"
            },
            {
                "name": "T.Z. Xin",
                "org": "School of Material Science and Engineering"
            },
            {
                "name": "Y. Luo",
                "org": "Department of Chemistry"
            },
            {
                "name": "F.P. Wang",
                "org": "School of Chemical Engineering and Technology"
            }
        ],
        "title": "In vitro degradation of AZ31 magnesium alloy coated with hydroxyapatite by sol-gel method",
        "abstract": "In recent years, magnesium and its alloys have been proposed as a new class of metallic bioabsorbable implant material. Unfortunately, the rapid corrosion rate of magnesium alloys could result in the accumulation of the hydrogen gas and the reduction in the mechanical properties before the healing of bone tissue. It is necessary to develop biocompatible coatings to delay the degradation rate. In the present research, hydroxyapatite coatings are successfully deposited on AZ31 magnesium alloy by sol-gel technique to slow down the degradation and improve the bioactivity. The structure, composition and chemical states of the sol-gel coatings are characterised by scanning electron microscopy, X-ray diffraction and X-ray photoelectron spectroscopy. The bonding strength, corrosion behaviours and hydrogen evolution rate of the samples are also studied. The results show that improving the heat treatment temperature can improve the corrosion resistance and the bonding strength between the coating and the substrate. The degradation rate of the samples reduces with improving heat treatment temperature. However, the lowest hydrogen evolution rate is still much higher than the tolerated level of human body. Because of the low melting point of magnesium alloy, it is difficult to reduce the hydrogen evolution rate to the tolerated level of human body only by improving the heat treatment temperature. \u00a9 2013 Institute of Materials, Minerals and Mining.",
        "keywords": [
            "Bonding strength",
            "Corrosion resistance",
            "Hydrogen evolution",
            "Hydroxyapatite",
            "Magnesium alloy",
            "Sol-gel"
        ],
        "venue": "Materials Science and Technology (United Kingdom)",
        "year": 2013,
        "id": "35w4SbWG"
    },
    "rL8AKNjI": {
        "authors": [
            {
                "name": "J. Liu",
                "org": "College of Veterinary Medicine"
            },
            {
                "name": "Y. Wang",
                "org": "College of Veterinary Medicine"
            },
            {
                "name": "J. Su",
                "org": "College of Veterinary Medicine"
            },
            {
                "name": "Y. Luo",
                "org": "College of Veterinary Medicine"
            },
            {
                "name": "F. Quan",
                "org": "College of Veterinary Medicine"
            },
            {
                "name": "Y. Zhang",
                "org": "College of Veterinary Medicine"
            }
        ],
        "title": "Nuclear donor cell lines considerably influence cloning efficiency and the incidence of large offspring syndrome in bovine somatic cell nuclear transfer",
        "abstract": "Total five ear skin fibroblast lines (named F1, F2, F3, F4 and F5) from different newborn Holstein cows have been used as nuclear donor cells for producing cloned cows by somatic cell nuclear transfer (SCNT). The effects of these cell lines on both in vitro and in vivo developmental rates of cloned embryos, post-natal survivability and incidence of large offspring syndrome (LOS) were examined in this study. We found that the different cell lines possessed the same capacity to support pre-implantation development of cloned embryos, the cleavage and blastocyst formation rates ranged from 80.2\u00a0\u00b1\u00a00.9 to 84.5\u00a0\u00b1\u00a02.5% and 28.5\u00a0\u00b1\u00a00.9 to 33.3\u00a0\u00b1\u00a01.4%, respectively. However, their capacities to support the in vivo development of SCNT embryos showed significant differences (p\u00a0<\u00a00.05). The pregnancy rates at 90 and 240\u00a0day were significantly lower in groups F2 (4.9% and 3.3%) and F3 (5.4% and 5.4%) compared to groups F1 (23.3% and 16.3%), F4 (25.7% and 18.6%) and F5 (25.9% and 19.8%) (p\u00a0<\u00a00.05). The cloning efficiency was significantly higher in group F5 than those in group F1, F2, F3 and F4 (9.3% vs 4.1%, 1.2%, 2.0% and 5.0%, respectively, p\u00a0<\u00a00.05). Moreover, large offspring syndrome (LOS) incidence in group F5 was significantly lower than those in other groups (p\u00a0<\u00a00.05). All cloned offspring from cell line F1, F2, F3 and F4 showed LOS and gestation length delay, while all cloned offspring from F5 showed normal birthweight and gestation length. We concluded that the nuclear donor cell lines have significant impact on the in vivo development of cloned embryos and the incidence of LOS in cloned calves. \u00a9 2013 Blackwell Verlag GmbH.",
        "keywords": [
            ""
        ],
        "venue": "Reproduction in Domestic Animals",
        "year": 2013,
        "id": "rL8AKNjI"
    },
    "a0T8XSy4": {
        "authors": [
            {
                "name": "J. Huang",
                "org": "Department of Ophthalmology"
            },
            {
                "name": "X. Li",
                "org": "Department of Hepatobiliary Surgery"
            },
            {
                "name": "M. Li",
                "org": "State Key Laboratory of Ophthalmology"
            },
            {
                "name": "J. Li",
                "org": "Department of Ophthalmology"
            },
            {
                "name": "W. Xiao",
                "org": "State Key Laboratory of Ophthalmology"
            },
            {
                "name": "W. Ma",
                "org": "State Key Laboratory of Ophthalmology"
            },
            {
                "name": "X. Chen",
                "org": "State Key Laboratory of Ophthalmology"
            },
            {
                "name": "X. Liang",
                "org": "State Key Laboratory of Ophthalmology"
            },
            {
                "name": "S. Tang",
                "org": "State Key Laboratory of Ophthalmology"
            },
            {
                "name": "Y. Luo",
                "org": "State Key Laboratory of Ophthalmology"
            }
        ],
        "title": "Mitochondria-targeted antioxidant peptide SS31 protects the retinas of diabetic rats",
        "keywords": [
            "Diabetic rat",
            "Oxidative damage",
            "Retina",
            "SS31"
        ],
        "venue": "Current Molecular Medicine",
        "year": 2013,
        "id": "a0T8XSy4"
    },
    "C9Qn44xr": {
        "authors": [
            {
                "name": "H. Chen",
                "org": "Institute of Physics"
            },
            {
                "name": "Z.Q. Li",
                "org": "Institute of Physics"
            },
            {
                "name": "H.F. Liu",
                "org": "Institute of Physics"
            },
            {
                "name": "L. Wan",
                "org": "Institute of Physics"
            },
            {
                "name": "M.H. Zhang",
                "org": "Institute of Physics"
            },
            {
                "name": "Q. Huang",
                "org": "Institute of Physics"
            },
            {
                "name": "J.M. Zhou",
                "org": "Institute of Physics"
            },
            {
                "name": "Y. Luo",
                "org": "Dept. Electron. Eng. Lab. Adv. Mat."
            },
            {
                "name": "Y.J. Han",
                "org": "Dept. Electron. Eng. Lab. Adv. Mat."
            },
            {
                "name": "K. Tao",
                "org": "Dept. Electron. Eng. Lab. Adv. Mat."
            },
            {
                "name": "N. Yang",
                "org": "Dept. Electron. Eng. Lab. Adv. Mat."
            }
        ],
        "title": "Controllable cubic and hexagonal GaN growth on GaAs(001) substrates by molecular beam epitaxy",
        "abstract": "Two kinds of GaN samples were grown on GaAs(001) substrates. One is grown on nitridized GaAs surface, the other is grown on nitridized AlAs buffer GaAs substrate. X-ray diffraction and photoluminescence measurements find that the GaN sample directly grown on GaAs substrate is pure cubic phase and those grown on AlAs buffer is pure hexagonal phase. The present study shows that the phase of GaN samples grown on GaAs substrates can be controlled using different buffer layers.",
        "keywords": [
            ""
        ],
        "venue": "Journal of Crystal Growth",
        "year": 2000,
        "id": "C9Qn44xr"
    },
    "IADVMY1C": {
        "authors": [
            {
                "name": "Hongfei Liu",
                "org": "Institute of Physics"
            },
            {
                "name": "H. Chen",
                "org": "Institute of Physics"
            },
            {
                "name": "Zhiqiang Li",
                "org": "Institute of Physics"
            },
            {
                "name": "Li Wan",
                "org": "Institute of Physics"
            },
            {
                "name": "Q. Huang",
                "org": "Institute of Physics"
            },
            {
                "name": "Jiunming Zhou",
                "org": "Institute of Physics"
            },
            {
                "name": "N. Yang",
                "org": ""
            },
            {
                "name": "Kun Tao",
                "org": "Laboratory of Advanced Materials"
            },
            {
                "name": "Y.J. Han",
                "org": ""
            },
            {
                "name": "Y. Luo",
                "org": "Department of Electronic Engineering"
            }
        ],
        "title": "Growth and properties of hexagonal GaN on GaAs(0 0 1) substrate by RF-molecular beam epitaxy using an AlAs nucleation layer",
        "abstract": "Hexagonal gallium nitride (h-GaN) films of about 400 nm are grown by using radio frequency (RF) plasma source assisted molecular beam epitaxy on (0 0 1)-oriented GaAs substrate. Before the growth of GaN epilayer an AlAs layer of about 10 nm was grown at 700 \u00b0C and nitridized with the temperature ramping from 540 to 730 \u00b0C. Then low-temperature GaN or AlN was grown as the buffer layer. The epilayers were characterized by using high-resolution X-ray diffraction (HRXRD), atomic force microscopy (AFM), and Raman scattering. By using AlN instead of GaN as the buffer layer, the GaN epilayer quality and morphology are significantly improved.",
        "keywords": [
            ""
        ],
        "venue": "Journal of Crystal Growth",
        "year": 2000,
        "id": "IADVMY1C"
    },
    "sbVo4qEa": {
        "authors": [
            {
                "name": "Z.Q. Li",
                "org": "Institute of Physics"
            },
            {
                "name": "H. Chen",
                "org": "Institute of Physics"
            },
            {
                "name": "H.F. Liu",
                "org": "Institute of Physics"
            },
            {
                "name": "L. Wan",
                "org": "Institute of Physics"
            },
            {
                "name": "M.H. Zhang",
                "org": "Institute of Physics"
            },
            {
                "name": "Q. Huang",
                "org": "Institute of Physics"
            },
            {
                "name": "J.M. Zhou",
                "org": "Institute of Physics"
            },
            {
                "name": "N. Yang",
                "org": "Laboratory of Advanced Materials"
            },
            {
                "name": "K. Tao",
                "org": "Laboratory of Advanced Materials"
            },
            {
                "name": "Y. Han",
                "org": "Laboratory of Advanced Materials"
            },
            {
                "name": "Y. Luo",
                "org": "Laboratory of Advanced Materials"
            }
        ],
        "title": "Influence of Si doping on optical characteristics of cubic GaN grown on (001) GaAs substrates",
        "abstract": "The photoluminescence (PL) properties of Si-doped cubic GaN with different carrier concentrations were investigated at room temperature. The epilayers were grown on GaAs (001) by radio-frequency molecular-beam epitaxy. It was found that when the carrier concentration is increased from 5 \u00d7 10",
        "keywords": [
            ""
        ],
        "venue": "Applied Physics Letters",
        "year": 2000,
        "id": "sbVo4qEa"
    },
    "CN0XUcKV": {
        "authors": [
            {
                "name": "H.F. Liu",
                "org": "Institute of Physics"
            },
            {
                "name": "H. Chen",
                "org": "Institute of Physics"
            },
            {
                "name": "Z.Q. Li",
                "org": "Institute of Physics"
            },
            {
                "name": "L. Wan",
                "org": "Institute of Physics"
            },
            {
                "name": "Q. Huang",
                "org": "Institute of Physics"
            },
            {
                "name": "J.M. Zhou",
                "org": "Institute of Physics"
            },
            {
                "name": "N. Yang",
                "org": "Advanced Material Lab."
            },
            {
                "name": "K. Tao",
                "org": "Advanced Material Lab."
            },
            {
                "name": "Y.J. Han",
                "org": "Department of Electronic Engineering"
            },
            {
                "name": "Y. Luo",
                "org": "Department of Electronic Engineering"
            }
        ],
        "title": "MBE growth and Raman studies of cubic and hexagonal GaN films on (0 0 1)-oriented GaAs substrates",
        "abstract": "Using different nucleation layers, we have grown cubic and hexagonal GaN epilayers on (0 0 1)-oriented GaAs substrates by radio-frequency plasma-assisted molecular beam epitaxy. First- and second-order Raman spectra are taken from these epilayers in back-scattering configurations at room temperature. For the first-order Raman spectra, transverse-optical (TO) phonons and longitudinal-optical (LO) phonons of cubic GaN are found to be at 533 and 739 cm",
        "keywords": [
            ""
        ],
        "venue": "Journal of Crystal Growth",
        "year": 2000,
        "id": "CN0XUcKV"
    },
    "XGY7f6Go": {
        "authors": [
            {
                "name": "Z.B. Hao",
                "org": "Dep. of Electronic Eng."
            },
            {
                "name": "J.H. Lu",
                "org": "Dep. of Electronic Eng."
            },
            {
                "name": "Z.Y. Ren",
                "org": "Dep. of Electronic Eng."
            },
            {
                "name": "Y. Luo",
                "org": "Dep. of Electronic Eng."
            }
        ],
        "title": "Solid-Source Molecular Beam Epitaxial growth of InP and InGaAsP",
        "abstract": "All-solid-source molecular beam epitaxy (SSMBE) growth in InP and InGaAsP was reported using a three-temperature-zone valved cracker cell based upon a homemade MBE system. High quality InP films were grown with surface defect density of 65 cm",
        "keywords": [
            "InGaAsp",
            "InP",
            "MBE"
        ],
        "venue": "Pan Tao Ti Hsueh Pao/Chinese Journal of Semiconductors",
        "year": 2000,
        "id": "XGY7f6Go"
    },
    "34D1hcEN": {
        "authors": [
            {
                "name": "Z. Dong",
                "org": ""
            },
            {
                "name": "Y. Luo",
                "org": ""
            },
            {
                "name": "J. Zheng",
                "org": ""
            },
            {
                "name": "T. Li",
                "org": ""
            }
        ],
        "title": "Grey evaluation of corrosive status of underground oil pipelines",
        "abstract": "The statistical maths analysis and sample distribution assumption tests of four factors, i.e., pipe-earth potential (PEP), cathodically protected potential (CPP), corrosion current density (CCD) of 16 Mn mild steel in soil and coating resistance (CR) have been accomplished. The CCD and CPP have the same normal distribution in both new and old pipelines. In contrast, the PEP and CR are submitted to log-normal distribution. A gray target identification model is used to evaluate and to classify the comprehensive corrosion and protection status of the oil pipelines. The result indicates that the classification is useful for the preventive repair on pipelines.",
        "keywords": [
            "Corrosion invalidation",
            "Gray identification",
            "Oil pipeline",
            "Statistics analysis"
        ],
        "venue": "Huazhong Ligong Daxue Xuebao/Journal Huazhong (Central China) University of Science and Technology",
        "year": 2001,
        "id": "34D1hcEN"
    },
    "3DXwboZo": {
        "authors": [
            {
                "name": "Y. Luo",
                "org": "Huazhong Univ. of Sci. and Technol."
            },
            {
                "name": "G. Tu",
                "org": "Huazhong Univ. of Sci. and Technol."
            },
            {
                "name": "J. Zhang",
                "org": "Huazhong Univ. of Sci. and Technol."
            },
            {
                "name": "Z. Shen",
                "org": "Huazhong Univ. of Sci. and Technol."
            },
            {
                "name": "X. Zhan",
                "org": "Huazhong Univ. of Sci. and Technol."
            }
        ],
        "title": "Digitized comprehensive transmission plan of substation information",
        "abstract": "Principles, technical conditions and methods of digitized comprehensive transmission of substation information on telemetering, telesignalization, telecontrol, teleadjusting, remote viewing, remote diagnosis and maintenance, and fault recording by IP technology are described. It is pointed out that the key technique is how to allocate the transmission bandwidth of various types of information and how to control the transmission flow of information. A bandwidth allocating method of giving first priority to the information with strong real-time properties and a method of constraining transmission flow by controlling different transmission rate for various types of information from the sender are proposed. With respect to communication software, the concept of communication soft interface is presented. The communication software is divided into two layers, the IP transmitting layer and the protocol encoding/decoding layer, which is advantageous to the standardization of the transmission protocol. It has been proved that the method proposed can meet the real-time requirements for various types of information by the E1 channel test. The conclusion is also applicable to broadband data transmission based on IP technology.",
        "keywords": [
            "Digitized comprehensive transmission of information",
            "IP technology",
            "Soft interface",
            "Substation automation"
        ],
        "venue": "Dianli Xitong Zidonghue/Automation of Electric Power Systems",
        "year": 2001,
        "id": "3DXwboZo"
    },
    "xJSKtbhU": {
        "authors": [
            {
                "name": "Y. Luo",
                "org": "Huazhong Univ. of Sci. and Technol."
            },
            {
                "name": "G. Tu",
                "org": "Huazhong Univ. of Sci. and Technol."
            },
            {
                "name": "J. Zhang",
                "org": "Huazhong Univ. of Sci. and Technol."
            },
            {
                "name": "X. Zhen",
                "org": "Huazhong Univ. of Sci. and Technol."
            }
        ],
        "title": "The application of multimedia technology to substation automation and the communication modes",
        "abstract": "By applying multimedia technology to the substation automation can implement the acquisition and teletransmission of video and audio information to meet the needs of substation environment monitoring and so on, which is advantageous to realizing genuine unattended substation. Three factors are presented that are of influence on the application of multimedia technology to substation automation, which are video information transmission, the integration of multi-modality input and engineering funds. Two typical modes of communication between master station and substation are given and analyzed, one is the point-to-multipoint and the other is the wide area network (TCP/IP) mode. It is pointed out that the wide area network (TCP/IP) mode is the trend of technological development.",
        "keywords": [
            "Multi-media",
            "Substation automation",
            "TCP/IP",
            "Wide area network"
        ],
        "venue": "Dianli Xitong Zidonghue/Automation of Electric Power Systems",
        "year": 2001,
        "id": "xJSKtbhU"
    },
    "tzT4cZ5g": {
        "authors": [
            {
                "name": "Y. Luo",
                "org": "Huazhong Univ. of Science/Technology"
            },
            {
                "name": "G. Tu",
                "org": "Huazhong Univ. of Science/Technology"
            },
            {
                "name": "J. Zhang",
                "org": "Huazhong Univ. of Science/Technology"
            },
            {
                "name": "X. Zhan",
                "org": "Huazhong Univ. of Science/Technology"
            },
            {
                "name": "Z. Cheng",
                "org": "Huazhong Univ. of Science/Technology"
            }
        ],
        "title": "A multimedia automation system for substation",
        "abstract": "By combining multimedia technology and TCP/IP based network technology with the substation automation, a new idea of substation multimedia automation system is proposed to realize digitized transmission of multimedia information between master station and substation. The architecture and functions of the new substation multimedia automation system are explained. Two main technical problems about the system are analyzed, that is, camera selection and teletransmission of the information. A scheme for adding the function of multimedia information acquisition and transmission to the existing substation automation system by adopting the multimedia RTU is also proposed.",
        "keywords": [
            "Multimedia",
            "RTU",
            "Substation automation",
            "TCP/IP"
        ],
        "venue": "Dianli Xitong Zidonghue/Automation of Electric Power Systems",
        "year": 2001,
        "id": "tzT4cZ5g"
    },
    "OOQanxRH": {
        "authors": [
            {
                "name": "J. Zhang",
                "org": "Huazhong Univ. of Sci. and Technol."
            },
            {
                "name": "Y. Luo",
                "org": "Huazhong Univ. of Sci. and Technol."
            },
            {
                "name": "G. Tu",
                "org": "Huazhong Univ. of Sci. and Technol."
            },
            {
                "name": "X. Zhan",
                "org": "Huazhong Univ. of Sci. and Technol."
            },
            {
                "name": "Z. Cheng",
                "org": "Huazhong Univ. of Sci. and Technol."
            }
        ],
        "title": "The design of a multimedia master station system",
        "abstract": "Based on an analysis of the main problems arising from the introduction of multimedia technology into the existing monitoring master station, the design of the multimedia master station system is proposed. The technical problems are clarified and the corresponding solutions are given. (1) Because there are several supervisors for remote viewing, the contradiction between safe operation and monitoring control can be avoided by installing the indispensable main controller and secondary controllers. (2) The operation state and video information of substations should be displayed on the same screen. (3) Appropriate measures should be taken for the data processing, storing and communication in the multimedia master station systems. Two schemes of implementing the multimedia master station are proposed, one is interconnecting the EMS with the remote viewing system and the other is an integrated master station system by wide area network.",
        "keywords": [
            "Dispatching automation",
            "EMS",
            "Master station",
            "Multimedia"
        ],
        "venue": "Dianli Xitong Zidonghue/Automation of Electric Power Systems",
        "year": 2001,
        "id": "OOQanxRH"
    },
    "64rxIUnF": {
        "authors": [
            {
                "name": "Y. Luo",
                "org": "Huazhong Univ. of Sci. and Technol."
            }
        ],
        "title": "Distributed fault recording system",
        "abstract": "The synchronizing technology, data storing technology, the technology of coordinated start of record-collecting units and communicating technology are key technologies to a recording system. A synchronizing method adapted to the distributed fault recording system is proposed which consists of synchronizing the sampling pulses of various record-collecting units by means of the pulse signals per second of GPS followed by the synchronization of the sequence of sampled values by adopting the software auto-synchronizing algorithm. The method of starting the record-collecting unit and the effect of such a starting method on the data collecting window are discussed. It can be seen from analysis that the adoption of the distributed storage for recorded data can solve the problem of insufficient storing capacity of the concentrated fault recording system and the pressing time for retransmission. It is proposed that the TCP/IP-based network communication should be adopted as the mode of communication between the master recording station and record-collecting units. Presented in this paper are the construction of the IP addressing distributed fault-recording system and conclusions about dynamic analog tests on a prototype.",
        "keywords": [
            "Distributed",
            "Fault recording",
            "GPS",
            "IP",
            "Synchro-sampling"
        ],
        "venue": "Dianli Xitong Zidonghue/Automation of Electric Power Systems",
        "year": 2001,
        "id": "64rxIUnF"
    },
    "nQew0yo2": {
        "authors": [
            {
                "name": "Z. Dong",
                "org": "Chemistry Department"
            },
            {
                "name": "Y. Luo",
                "org": "Chemistry Department"
            },
            {
                "name": "J. Zheng",
                "org": "Chemistry Department"
            },
            {
                "name": "D. Yu",
                "org": "Chemistry Department"
            },
            {
                "name": "T. Li",
                "org": "Chemistry Department"
            }
        ],
        "title": "Grey assess and statistic analysis of corrosion status of long-distance oil pipeline",
        "abstract": "Most underground long - distance oil pipelines have overrun the designed lifetime presently. Therefore, hazard estimation and prediction of aged pipelines is more imperative than before. In the present paper, mathematical statistical analyses and sample distribution assumption test of four factors i. e. Pipe - Earth Potential (\u03c6",
        "keywords": [
            "Corrosion invalidation",
            "Gray target identification",
            "Hazard assessment",
            "Oil pipeline"
        ],
        "venue": "Corrosion Science and Protection Technology",
        "year": 2001,
        "id": "nQew0yo2"
    },
    "SM9vZNcN": {
        "authors": [
            {
                "name": "G. Sheng",
                "org": "Coll. of Elec. and Electron. Eng."
            },
            {
                "name": "G. Tu",
                "org": "Coll. of Elec. and Electron. Eng."
            },
            {
                "name": "Y. Luo",
                "org": "Coll. of Elec. and Electron. Eng."
            }
        ],
        "title": "A new secondary voltage control scheme based on multi-agent technology",
        "abstract": "Secondary voltage control (SVC) has been developed by a number of electric utilities to prevent voltage deterioration and keep a better use of existing reactive power resources. However, there still exist limitations. In this article, a new SVC scheme using the distributed hierarchical control methodologies based on multi-agent system (MAS) theory is proposed to overcome the disadvantages of the conventional secondary voltage control system. The basic configuration, operating mechanism and implementation methods of the new MAS-based control scheme are designed and described in detail. The purpose of the proposed scheme applied to regional voltage control in power system is to coordinate primary voltage controllers quickly, effectively and reliably, and then to maintain an appropriate voltage profile under both normal and contingency conditions. The simulation results of two different test systems are presented to illustrate the validity of the proposed control scheme.",
        "keywords": [
            "Multi-agent",
            "Power systems",
            "Secondary voltage control",
            "Voltage stability"
        ],
        "venue": "International Journal of Power and Energy Systems",
        "year": 2003,
        "id": "SM9vZNcN"
    },
    "ITyQ3ndV": {
        "authors": [
            {
                "name": "L. Shi",
                "org": "School of Electrical and Electronic Engineering"
            },
            {
                "name": "Y. Luo",
                "org": "School of Electrical and Electronic Engineering"
            },
            {
                "name": "G.Y. Tu",
                "org": "School of Electrical and Electronic Engineering"
            }
        ],
        "title": "Bidding strategy of microgrid with consideration of uncertainty for participating in power market",
        "abstract": "Microgrid is commonly regarded as an efficient way for integration of distributed generation (DG) in low voltage network. However, the integration method of microgrid in power system for maximum benefit needs to be further promoted. In this paper, a stochastic bidding strategy of microgrid in a joint day-ahead market of energy and spinning reserve service is proposed taking into account of uncertainty of renewable DG units' output power and load. The stochastic bidding strategy is modeled as bi-level optimization problem and can be divided into two steps. First, Latin Hypercube Sampling (LHS) is utilized for generating microgrid uncertain net power scenarios according to day-ahead uncertain power scenario models, and then reduced by backward scenario reduction technique for less computation. Second, the upper level total bidding profit including bidding revenue, expected imbalance and operation cost is optimized by interior point algorithm in MATLAB for making optimal bids. The expected imbalance and operation cost is calculated by iteratively invoking lower level deterministic unit commitment under each microgrid uncertain net power scenario. The lower level deterministic unit commitment is coded and solved by mixed integer nonlinear programming (MINLP) solver DICOPT in GAMS. Finally, the optimal energy and spinning reserve bids are given by solving the bi-level bidding model. The model is applied to a modified typical low-voltage microgrid and the effectiveness and excellence of proposed strategy is proven by comparing simulation results with traditional deterministic bidding strategy. \u00a9 2014 Elsevier Ltd. All rights reserved.",
        "keywords": [
            "Bidding strategy",
            "Energy market",
            "Microgrid",
            "Spinning reserve market",
            "Uncertainty"
        ],
        "venue": "International Journal of Electrical Power and Energy Systems",
        "year": 2014,
        "id": "ITyQ3ndV"
    },
    "bHmr1W6v": {
        "authors": [
            {
                "name": "L. Qi",
                "org": "China University of Geosciences"
            },
            {
                "name": "J. Pei",
                "org": "China University of Geosciences"
            },
            {
                "name": "K. Zhou",
                "org": "China University of Geosciences"
            },
            {
                "name": "G. Shi",
                "org": "China University of Geosciences"
            },
            {
                "name": "Y. Luo",
                "org": "China University of Geosciences"
            }
        ],
        "title": "Crystal defect and growth mechanism of alkali-Rich beryl crystal from Pingwu, Sichuan, Chian",
        "abstract": "The beryl crystal from Pingwu County, Sichuan Province that occurred on the low-saturation, alkaline and pneumatogenic - thermal conditions, is characterized by the flat tabular shape. On the crystal surfaces of the beryl crystal at {0001}, {101\u03040}, {11\u030421} occur universally screw dislocation, constriction screw dislocation, stacking fault, and contact twin that serve as the major step-like source for the growth of beryl crystal. The research results obtained through differential interference microscope, scanning electron microscope, and transmission electron microscope show that the comprehensive effects of interstitial deformation, dislocation sliding and hydrolytic weakening lead directly to the local deformation of the silica tetrahedral hexagonal ring-like structure and the beryllium oxide tetragonal structure, and at the same time to the change in polyhedral volume, chemical bond force, bonding energy, and in the normal growth rate of the crystal face. These changes determine the morphology of the beryl crystal growth in this zone. The formation of the flat tabular beryl crystal in Sichuan Province is attributed mainly to the synergy of the linear defects (screw dislocation), face defects (stacking fault and twining) and point defects (vacancy and inclusion) in the beryl crystal.",
        "keywords": [
            "Beryl",
            "Crystal defect",
            "Growth mechanism",
            "Screw dislocation"
        ],
        "venue": "Dizhi Keji Qingbao/Geological Science and Technology Information",
        "year": 2001,
        "id": "bHmr1W6v"
    },
    "cY4MRz3s": {
        "authors": [
            {
                "name": "G. Liu",
                "org": "Inst. Natl. Land/Rsrc. Info. Syst."
            },
            {
                "name": "Z. Han",
                "org": "Inst. Natl. Land/Rsrc. Info. Syst."
            },
            {
                "name": "Y. Luo",
                "org": "Inst. Natl. Land/Rsrc. Info. Syst."
            },
            {
                "name": "C. Wu",
                "org": "Inst. Natl. Land/Rsrc. Info. Syst."
            }
        ],
        "title": "Research into application framework of parametric design method of computer-aided map generation in resources exploration information system",
        "abstract": "Because of some disadvantages of current CAD technology, the design efficiency and application of computer-aided resources map generation system in different departments and users were limited. In this paper a new parametric graph design method is presented to solve this problem. Based on the analysis of map generation system features and parametric design theory, difficulties and means of the application approaches of the system to parametric design method and actual parametric design system are put forward, such as map model design and reuses, adaptability of map model itself and establishment of parametric graph library. The realization and application of parametric design method may improve prominently the functional agility and flexibility of map generation system.",
        "keywords": [
            "Computer-aided design (CAD)",
            "Geological and mineral point-source information system",
            "Parametric design method",
            "Resources map generation"
        ],
        "venue": "Diqiu Kexue Zhongguo Dizhi Daxue Xuebao/Earth Science - Journal of China University of Geosciences",
        "year": 2001,
        "id": "cY4MRz3s"
    },
    "fFNU2O0n": {
        "authors": [
            {
                "name": "S. Ye",
                "org": ""
            },
            {
                "name": "L. Qi",
                "org": ""
            },
            {
                "name": "Y. Luo",
                "org": ""
            },
            {
                "name": "K. Zhou",
                "org": ""
            },
            {
                "name": "J. Pei",
                "org": ""
            }
        ],
        "title": "Relationship between the rare-metal contained granitic intrusions and beryl mineralization in Pingwu, Sichuan, China",
        "abstract": "This paper presents lithogeochemical characteristics of the rarefaction metal granite mass in Pingwu, Sichuan and discusses preliminarily the relationship between the granite and Be, W, Sn minerogenesis. The forming minerals of the granite mass rock are composed of quartz, albite, potassium-feldspar and phlogopite in Pingwu. Its petrochemical compositions are supersaturated Al, rich Na and inclined to alkaly. Its REE content is very low but its rare elements are many such as Be, W, Sn, Li, Ta, Rb etc. The granite mass is formed by high differentiation evolution of granite magma at its latest stage. While the pneumatolytic-hydrothermal deposits of beryl, scheclite and casiterite are formed by the postmagmatic greisenization.",
        "keywords": [
            "Beryl gem",
            "Mineralization",
            "Petrochemistry and geochemistry",
            "Rare metal granite"
        ],
        "venue": "Dizhi Keji Qingbao/Geological Science and Technology Information",
        "year": 2001,
        "id": "fFNU2O0n"
    },
    "Cqx3AkjH": {
        "authors": [
            {
                "name": "L. Qi",
                "org": "China University of Geosciences"
            },
            {
                "name": "C. Xiang",
                "org": "China University of Geosciences"
            },
            {
                "name": "G. Liu",
                "org": "China University of Geosciences"
            },
            {
                "name": "J. Pei",
                "org": "China University of Geosciences"
            },
            {
                "name": "Y. Luo",
                "org": "China University of Geosciences"
            }
        ],
        "title": "ESR behaviour of paramagnetic mixture in irradiated beryl",
        "abstract": "The NaH, [Fe",
        "keywords": [
            "ESR spectrum",
            "Irradiated beryl",
            "Radiation treatment",
            "Resonance transition"
        ],
        "venue": "Dizhi Keji Qingbao/Geological Science and Technology Information",
        "year": 2001,
        "id": "Cqx3AkjH"
    },
    "G3MkKzZF": {
        "authors": [
            {
                "name": "S. Huang",
                "org": "China University of Geosciences"
            },
            {
                "name": "X. Ma",
                "org": "China University of Geosciences"
            },
            {
                "name": "Y. Luo",
                "org": "China University of Geosciences"
            }
        ],
        "title": "Analysis of safety benefits and models in geological engineering",
        "abstract": "The article discussed safety benefits and studied safety models in geological engineering from the point of view that safety increase output and decrease loss. The authors further detailed the method of calculating safety increase benefits, which is very helpful for geological engineering corporations to calculate their economic benefits.",
        "keywords": [
            "Decrease loss",
            "Geological engineering",
            "Safety benefit",
            "Safety increase output"
        ],
        "venue": "Dizhi Keji Qingbao/Geological Science and Technology Information",
        "year": 2001,
        "id": "G3MkKzZF"
    },
    "aX2YUaKJ": {
        "authors": [
            {
                "name": "B. Ji",
                "org": "Dept. of Control Sci. and Eng."
            },
            {
                "name": "H. Xiao",
                "org": "Dept. of Control Sci. and Eng."
            },
            {
                "name": "Y. Luo",
                "org": "Dept. of Control Sci. and Eng."
            }
        ],
        "title": "Study on pesudo-transitive rational choice function and revealed preference representation",
        "abstract": "The problem of rational choice functions revealed preference representation is investigated. By defining local strictly revealed preference, revealed preference axiom of pseudo-transitive rational choice function is proposed. It is shown that a choice function is rationalized by a pseudo-transitive ordering if and only if it satisfies the axiom. This extends revealed preference representation from fully rational choice function to pesudo-transitive rational.",
        "keywords": [
            "Axiom revealed preference",
            "Choice function",
            "Local strictly revealed preference",
            "Pesudo-transitive",
            "Revealed preference"
        ],
        "venue": "Huazhong Ligong Daxue Xuebao/Journal Huazhong (Central China) University of Science and Technology",
        "year": 2001,
        "id": "aX2YUaKJ"
    },
    "JRLhrgUb": {
        "authors": [
            {
                "name": "B. Ji",
                "org": ""
            },
            {
                "name": "X. Zhou",
                "org": ""
            },
            {
                "name": "Y. Luo",
                "org": ""
            },
            {
                "name": "D. Sun",
                "org": ""
            }
        ],
        "title": "Analysis of \"prisoners\" dilemma and Cartel coalition in oligopoly",
        "abstract": "This paper studies the decision-making behaviors of manufacturers in oligopoly. The correlation of manufacturers and the prisoners' dilemma due to the correlation are analyzed. The effectiveness of Cartel coalition is investigated and the principle of output dispense is given. The factors affecting the stability of Cartel coalition are also studied.",
        "keywords": [
            "Cartel",
            "Oligopoly",
            "Prisoners dilemma"
        ],
        "venue": "Huazhong Ligong Daxue Xuebao/Journal Huazhong (Central China) University of Science and Technology",
        "year": 2001,
        "id": "JRLhrgUb"
    },
    "8UWYoB96": {
        "authors": [
            {
                "name": "J. Xiao",
                "org": ""
            },
            {
                "name": "Y. Zhao",
                "org": ""
            },
            {
                "name": "Y. Luo",
                "org": ""
            },
            {
                "name": "C. Yue",
                "org": ""
            }
        ],
        "title": "A model for environmental pollution tax and the government control in the oligopoly market",
        "abstract": "In the oligopoly market two models of competition with environmental tax are built on the basis of the Cournot static game and the Stackelberg Dynamic game with complete information. The two models show the government's participation in and out of the game. The Nash equilibrium and subgame perfect Nash equilibrium are analyzed respectively. Relations between the government's optimal tax ratio and the firms' optimal production are discussed. The conclusion is applicable for other kinds of taxes.",
        "keywords": [
            "Cournot model",
            "Game theory",
            "Oligopoly",
            "Regulation",
            "Tax"
        ],
        "venue": "Huazhong Ligong Daxue Xuebao/Journal Huazhong (Central China) University of Science and Technology",
        "year": 2001,
        "id": "8UWYoB96"
    },
    "Jq4i3cbm": {
        "authors": [
            {
                "name": "J. Xiao",
                "org": "Institute of Systems Eng."
            },
            {
                "name": "Y. Luo",
                "org": "Institute of Systems Eng."
            },
            {
                "name": "Y. Zhao",
                "org": "Institute of Systems Eng."
            },
            {
                "name": "C. Yue",
                "org": "Institute of Systems Eng."
            }
        ],
        "title": "Competitive strategies of oligopoly enterprises affected by the envionmental tax",
        "abstract": "Under condition of oligopoly three models of competition with the environmental tax are established based on the Cournot game model and the Stackelberg game model. The models are built for overall cost leadership strategy, preferential share of market strategy and technique leadership strategy. Some helpful conclusions are drawn from the three models.",
        "keywords": [
            "Competitive strategy",
            "Cournot model",
            "Oligopoly",
            "Stackelberg model",
            "Tax"
        ],
        "venue": "Huazhong Ligong Daxue Xuebao/Journal Huazhong (Central China) University of Science and Technology",
        "year": 2001,
        "id": "Jq4i3cbm"
    },
    "QS56yic0": {
        "authors": [
            {
                "name": "Q. Cao",
                "org": "Dept. of Automatic Control Sci./Eng."
            },
            {
                "name": "X. Zhou",
                "org": "Dept. of Automatic Control Sci./Eng."
            },
            {
                "name": "Y. Luo",
                "org": "Dept. of Automatic Control Sci./Eng."
            }
        ],
        "title": "Effect of order of voting for binary voting procedure",
        "abstract": "The order of voting effect for the amendment procedure and the successive procedures in the following two cases are studied. One is that the voters have no information about each other's preferences and the other is that the voters know each other's preferences completely. And the strategies of voters are analyzed. The correlation between voters' preferences structure and voting procedure are given.",
        "keywords": [
            "Amendment procedure",
            "Order of voting effect",
            "Successive procedure"
        ],
        "venue": "Huazhong Ligong Daxue Xuebao/Journal Huazhong (Central China) University of Science and Technology",
        "year": 2001,
        "id": "QS56yic0"
    },
    "40sy8XVb": {
        "authors": [
            {
                "name": "Y. Peng",
                "org": "Dept. of Control Sci. and Eng."
            },
            {
                "name": "Y. Ning",
                "org": "Dept. of Control Sci. and Eng."
            },
            {
                "name": "Y. Luo",
                "org": "Dept. of Control Sci. and Eng."
            }
        ],
        "title": "Analysis of project election based on integer program",
        "abstract": "On the basis of analyzing three kinds of project election methods, the paper gives description in integer program of project election for the three kinds of methods. By analyzing the restriction conditions for project election with resource constrain, the integer program model for project election with resource constrain is given.",
        "keywords": [
            "Constrain condition",
            "Integer program",
            "Project election"
        ],
        "venue": "Huazhong Ligong Daxue Xuebao/Journal Huazhong (Central China) University of Science and Technology",
        "year": 2001,
        "id": "40sy8XVb"
    },
    "4uT7aF0o": {
        "authors": [
            {
                "name": "J. Xiao",
                "org": ""
            },
            {
                "name": "Y. Luo",
                "org": ""
            },
            {
                "name": "Y. Zhao",
                "org": ""
            },
            {
                "name": "C. Yue",
                "org": ""
            }
        ],
        "title": "Game analysis on selling initial permits by auction",
        "abstract": "A static game model with incomplete information based on the first-price sealed auction is established, which is used for selling initial permits by auction in the tradable emission permits system. The solution to Bayesian Nash equilibrium is discussed. Auction is proved to be a reasonable instrument for distributing initial permits. And it is concluded that the more firms participate in auction, the more benefits the government can get.",
        "keywords": [
            "Environmental protection",
            "First-price sealed auction",
            "Game",
            "Initial permits",
            "Tradable emission permits"
        ],
        "venue": "Huazhong Ligong Daxue Xuebao/Journal Huazhong (Central China) University of Science and Technology",
        "year": 2001,
        "id": "4uT7aF0o"
    },
    "Qpqe3GpW": {
        "authors": [
            {
                "name": "B. Ji",
                "org": ""
            },
            {
                "name": "Y. Tang",
                "org": ""
            },
            {
                "name": "Y. Luo",
                "org": ""
            }
        ],
        "title": "Study on standardization of teaching evaluation field",
        "abstract": "The paper is on the study of standardization of teaching evaluation in the universities. By analyzing the correlation of evaluation index, the paper give the hierarchy of evaluation index system for an excellent teaching project. Based on the research and defining attribute matrix, the calculating expression of the evaluating result and its standardization description are explored.",
        "keywords": [
            "Calculating expression of evaluating result",
            "Evaluating result",
            "Evaluation index system",
            "Teaching evaluation"
        ],
        "venue": "Huazhong Ligong Daxue Xuebao/Journal Huazhong (Central China) University of Science and Technology",
        "year": 2001,
        "id": "Qpqe3GpW"
    },
    "vGqiUksf": {
        "authors": [
            {
                "name": "Y. Tang",
                "org": "Dept. of Control Sci. and Eng."
            },
            {
                "name": "Y. Luo",
                "org": "Dept. of Control Sci. and Eng."
            }
        ],
        "title": "Analysis of relationship between inner revenue rate and cash flow model",
        "abstract": "The paper is a study on the relationship between inner revenue rate (IRR) and cash flow model. By analyzing the correlation between discount rate and cash flow model, it studies how cash flow model influences the existence of inner revenue rate, and it also investigates the consistence condition for net present value method and inner revenue rate method. On the basis of defining the modified inner revenue rate(MIRR), it gives formula of MIRR. And the application of IRR is extended.",
        "keywords": [
            "Cash flow model",
            "Inner revenue rate",
            "Modified inner revenue rate",
            "Technology economic"
        ],
        "venue": "Huazhong Ligong Daxue Xuebao/Journal Huazhong (Central China) University of Science and Technology",
        "year": 2001,
        "id": "vGqiUksf"
    },
    "1dxjYODB": {
        "authors": [
            {
                "name": "Y. Tang",
                "org": ""
            },
            {
                "name": "Y. Luo",
                "org": ""
            }
        ],
        "title": "Analysis of consistence for inner revenue rate and modified inner revenue rate",
        "abstract": "By analyzing the correlation of basic discount rate, inner revenue rate and modified inner revenue rate, the paper investigates the consistence for IRR Method and MIRR Method, and proves that whatever the basic discount rate is, the same result is given when the two methods are applied to proves election, i.e. there exists consistence in project election for two methods and the independence of basic discount rate. The paper studies the principle for ascertaining the basic discount rate.",
        "keywords": [
            "Basic discount rate",
            "Inner revenue rate",
            "Modified inner revenue rate",
            "Technology economy"
        ],
        "venue": "Huazhong Ligong Daxue Xuebao/Journal Huazhong (Central China) University of Science and Technology",
        "year": 2001,
        "id": "1dxjYODB"
    },
    "gHhz1UDJ": {
        "authors": [
            {
                "name": "K.W. Wong",
                "org": "Department of Physics and Materials Science and Technology Research Centre"
            },
            {
                "name": "H.L. Yip",
                "org": "Department of Physics and Materials Science and Technology Research Centre"
            },
            {
                "name": "Y. Luo",
                "org": "Department of Physics and Materials Science and Technology Research Centre"
            },
            {
                "name": "K.Y. Wong",
                "org": "Department of Physics and Materials Science and Technology Research Centre"
            },
            {
                "name": "W.M. Lau",
                "org": "Department of Physics and Materials Science and Technology Research Centre"
            },
            {
                "name": "K.H. Low",
                "org": "Department of Chemistry"
            },
            {
                "name": "H.F. Chow",
                "org": "Department of Chemistry"
            },
            {
                "name": "Z.Q. Gao",
                "org": "Varitronix Limited"
            },
            {
                "name": "W.L. Yeung",
                "org": "Varitronix Limited"
            },
            {
                "name": "C.C. Chang",
                "org": "Varitronix Limited"
            }
        ],
        "title": "Blocking reactions between indium-tin oxide and poly (3,4-ethylene dioxythiophene):poly(styrene sulphonate) with a self-assembly monolayer",
        "abstract": "In the fabrication of polymeric electroluminescent devices with indium-tin oxide (ITO) as anode, indium contamination of the polymers can greatly degrade the device performance. In the present study, we have used x-ray photoelectron spectroscopy to measure indium incorporation in poly(3,4-ethylene dioxythiophene):poly(styrene sulphonate), referred to as PEDOT:PSS, which were spincast on bare ITO and encapsulated ITO. We found that the deposition of a self-assembled monolayer of alkylsiloxanes on ITO prior to spincasting PEDOT:PSS was effective and practical in blocking the reactions between ITO and PEDOT:PSS. \u00a9 2002 American Institute of Physics.",
        "keywords": [
            ""
        ],
        "venue": "Applied Physics Letters",
        "year": 2002,
        "id": "gHhz1UDJ"
    },
    "FCYlWGbZ": {
        "authors": [
            {
                "name": "Y. Luo",
                "org": "Key Laboratory"
            },
            {
                "name": "M. Xu",
                "org": "Key Laboratory for Micro/Nano Technology and System of Liao Ning Province"
            },
            {
                "name": "X.D. Wang",
                "org": "Key Laboratory"
            },
            {
                "name": "C. Liu",
                "org": "Key Laboratory for Micro/Nano Technology and System of Liao Ning Province"
            }
        ],
        "title": "Finte element analysis of PMMA microfluidic chip based on hot embossing technique",
        "abstract": "Using creep experiment to characterize the mechanical property of PMMA has been studied in this paper. Polynomial and first order exponential decay function have been used to fit the data to get creep curve of PMMA. With the finite element analysis method and based on the creep and viscoelastic material models, simulation of the hot embossing process is carried out. Time influence on hot embossing has been emphasized. The simulation result is proved by experiments. It is shown that simulation based on viscoelastic model represents more compliance with experiments, and can describe the process of polymer deformation during hot embossing. \u00a9 2006 IOP Publishing Ltd.",
        "keywords": [
            ""
        ],
        "venue": "Journal of Physics: Conference Series",
        "year": 2006,
        "id": "FCYlWGbZ"
    },
    "hUBdv9Ic": {
        "authors": [
            {
                "name": "M. Xu",
                "org": "Key Laboratory for Precision and Non-traditional Machining"
            },
            {
                "name": "Y. Luo",
                "org": "Key Laboratory for Micro/Nano Technology and System of Liao Ning Province"
            },
            {
                "name": "X.D. Wang",
                "org": "Key Laboratory for Micro/Nano Technology and System of Liao Ning Province"
            },
            {
                "name": "C. Liu",
                "org": "Key Laboratory for Precision and Non-traditional Machining"
            }
        ],
        "title": "Fabrication of microfluidic chip using two substrates with different Tg temperature",
        "abstract": "Hot embossing method was used to fabricate microfluidic chips. Bonding tests were done with PMMA(polymethylmethacrylate), COP( cyclo-olefin polymer) 480R and COP1020R. Using two substrates with different glass transition temperature (Tg) can solve the problem of microstructure deformation in chip bonding. Temperature versus deformation curves of these three materials under certain pressing force were obtained. According to these curves, embossing reference temperature (Tr) can be determined for duplicating microstructure with high accuracy. By using two of the above-mentioned materials, successful bonding between COP480R and COP1020R were observed, while PMMA cannot be bonded with COP480R and COP1020R. Copyright \u00a9 2006 Frontiers of Design and Manufacturing.",
        "keywords": [
            "Bonding",
            "COP",
            "Hot embossing",
            "Microfluidic chip",
            "PMMA"
        ],
        "venue": "Current Development in Abrasive Technology - Proceedings of the 9th International Symposium on Advances in Abrasive Technology, ISAAT 2006",
        "year": 2006,
        "id": "hUBdv9Ic"
    },
    "eC8B9Art": {
        "authors": [
            {
                "name": "W.M. Lau",
                "org": ""
            },
            {
                "name": "Z. Zheng",
                "org": ""
            },
            {
                "name": "Y.H. Wang",
                "org": ""
            },
            {
                "name": "Y. Luo",
                "org": ""
            },
            {
                "name": "L. Xi",
                "org": ""
            },
            {
                "name": "K.W. Wong",
                "org": ""
            },
            {
                "name": "K.Y. Wong",
                "org": ""
            }
        ],
        "title": "Cross-linking organic semiconducting molecules by preferential C-H cleavage via \"chemistry with a tiny hammer\"",
        "keywords": [
            "Collision",
            "Cross-linking",
            "Device fabrication",
            "Dissociative collision",
            "Molecular electronics",
            "Organic semiconductor",
            "Polymer",
            "Polymeric semiconductor"
        ],
        "venue": "Canadian Journal of Chemistry",
        "year": 2007,
        "id": "eC8B9Art"
    },
    "Ta6oQWw2": {
        "authors": [
            {
                "name": "E. Carlegrim",
                "org": "Department of Science and Technology (ITN)"
            },
            {
                "name": "B. Gao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "A. Kanciurzewska",
                "org": "Department of Science and Technology (ITN)"
            },
            {
                "name": "M.P. De Jong",
                "org": "Department of Physics, Chemistry and Biology (IFM)"
            },
            {
                "name": "Z. Wu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Y. Luo",
                "org": "Department of Theoretical Chemistry"
            },
            {
                "name": "M. Fahlman",
                "org": "Department of Science and Technology (ITN)"
            }
        ],
        "title": "Near-edge x-ray absorption studies of Na-doped tetracyanoethylene films: A model system for the V (TCNE)x room-temperature molecular magnet",
        "abstract": "V (TCNE)x, with TCNE=tetracyanoethylene and x\u223c2, is an organic-based molecular magnet with potential to be used in spintronic devices. With the aim of shedding light on the unoccupied frontier electronic structure of V (TCNE)x we have studied pristine TCNE and sodium-intercalated TCNE by near edge x-ray absorption fine structure (NEXAFS) spectroscopy as well as with theoretical calculations. Sodium-intercalated TCNE was used as a model system of the more complex V (TCNE)x and both experimental and theoretical results of the model compound have been used to interpret the NEXAFS spectra of V (TCNE)x. By comparing the experimental and theoretical C K -edge of pristine TCNE, the contributions from the various carbon species (cyano and vinyl) could be disentangled. Upon fully sodium intercalation, TCNE is n doped with one electron per molecule and the features in the C and N K -edge spectra of pristine TCNE undergo strong modification caused by partially filling the TCNE lowest unoccupied molecular orbital (LUMO). When comparing the C and N K -edge NEXAFS spectra of fully sodium-doped TCNE with V (TCNE)x, the spectra are similar except for broadening of the features which originates from structural disorder of the V (TCNE)x films. The combined results from the model system and V (TCNE)x suggest that the lowest unoccupied molecular orbital with density on the nitrogen atoms in V (TCNE)x has no significant hybridization with vanadium and is similar to the so-called singly occupied molecular orbital of the TCNE anion. This suggests that the LUMO of V (TCNE)x is TCNE- or vanadiumlike, in contrast to the frontier occupied electronic structure where the highest occupied molecular orbital is a hybridization between V (3d) and cyano carbons. The completely different nature of the unoccupied and occupied frontier electronic structure of the material will most likely affect both charge injection and transport properties of a spintronic device featuring V (TCNE)x. \u00a9 2008 The American Physical Society.",
        "keywords": [
            ""
        ],
        "venue": "Physical Review B - Condensed Matter and Materials Physics",
        "year": 2008,
        "id": "Ta6oQWw2"
    },
    "WZ5mcqUG": {
        "authors": [
            {
                "name": "H.M. Zhong",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "Q. Liu",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure"
            },
            {
                "name": "J. Jiang",
                "org": "Department of Theoretical Chemistry"
            },
            {
                "name": "G.Y. Sun",
                "org": "Department of Physics"
            },
            {
                "name": "Y. Luo",
                "org": "Department of Theoretical Chemistry"
            }
        ],
        "title": "A first principles study on optical transparency mechanism in Dy doped \u03b1-SiAlON ceramics",
        "keywords": [
            ""
        ],
        "venue": "Journal of Applied Physics",
        "year": 2009,
        "id": "WZ5mcqUG"
    },
    "bIfJk6oF": {
        "authors": [
            {
                "name": "Z.C. Dong",
                "org": "Hefei National Laboratory for Physical Sciences at the Microscale"
            },
            {
                "name": "X.L. Zhang",
                "org": "Hefei National Laboratory for Physical Sciences at the Microscale"
            },
            {
                "name": "H.Y. Gao",
                "org": "Hefei National Laboratory for Physical Sciences at the Microscale"
            },
            {
                "name": "Y. Luo",
                "org": "Hefei National Laboratory for Physical Sciences at the Microscale"
            },
            {
                "name": "C. Zhang",
                "org": "Hefei National Laboratory for Physical Sciences at the Microscale"
            },
            {
                "name": "L.G. Chen",
                "org": "Hefei National Laboratory for Physical Sciences at the Microscale"
            },
            {
                "name": "R. Zhang",
                "org": "Hefei National Laboratory for Physical Sciences at the Microscale"
            },
            {
                "name": "X. Tao",
                "org": "Hefei National Laboratory for Physical Sciences at the Microscale"
            },
            {
                "name": "Y. Zhang",
                "org": "Hefei National Laboratory for Physical Sciences at the Microscale"
            },
            {
                "name": "J.L. Yang",
                "org": "Hefei National Laboratory for Physical Sciences at the Microscale"
            },
            {
                "name": "J.G. Hou",
                "org": "Hefei National Laboratory for Physical Sciences at the Microscale"
            }
        ],
        "title": "Generation of molecular hot electroluminescence by resonant nanocavity plasmons",
        "keywords": [
            ""
        ],
        "venue": "Nature Photonics",
        "year": 2010,
        "id": "bIfJk6oF"
    },
    "2SL7w0ft": {
        "authors": [
            {
                "name": "J. Jiang",
                "org": "Department of Theoretical Chemistry"
            },
            {
                "name": "B. Gao",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "Z.P. Hu",
                "org": "Hefei National Laboratory for Physical Science at the Microscale"
            },
            {
                "name": "Wei Lu",
                "org": "National Lab for Infrared Physics"
            },
            {
                "name": "Z.Y. Wu",
                "org": "Institute of High Energy Physics"
            },
            {
                "name": "J.L. Yang",
                "org": "Hefei National Laboratory for Physical Science at the Microscale"
            },
            {
                "name": "Y. Luo",
                "org": "Hefei National Laboratory for Physical Science at the Microscale"
            }
        ],
        "title": "Identification of metal-cage coupling in a single metallofullerene by inelastic electron tunneling spectroscopy",
        "keywords": [
            ""
        ],
        "venue": "Applied Physics Letters",
        "year": 2010,
        "id": "2SL7w0ft"
    },
    "uduqHHso": {
        "authors": [
            {
                "name": "J.-H. Guo",
                "org": "Advanced Light Source"
            },
            {
                "name": "S. Kastanov",
                "org": "Theoretical Chemistry"
            },
            {
                "name": "J. Soderstrom",
                "org": "Department of Physics"
            },
            {
                "name": "P.-A. Glans",
                "org": "Advanced Light Source"
            },
            {
                "name": "M. West",
                "org": "Advanced Light Source"
            },
            {
                "name": "T. Learmonth",
                "org": "Department of Physics"
            },
            {
                "name": "J.-W. Chiou",
                "org": "Department of Applied Physics"
            },
            {
                "name": "Y. Luo",
                "org": "Theoretical Chemistry"
            },
            {
                "name": "J. Nordgren",
                "org": "Department of Physics"
            },
            {
                "name": "K. Smith",
                "org": "Department of Physics"
            },
            {
                "name": "W.-F. Pong",
                "org": "Department of Physics"
            },
            {
                "name": "H. Cheng",
                "org": "Department of Laboratory Medicine and Veterans Affairs"
            },
            {
                "name": "J.M. Griffiss",
                "org": "Department of Laboratory Medicine and Veterans Affairs"
            }
        ],
        "title": "Electronic structure study of the bases in DNA duplexes by in situ photon-in/photon-out soft X-ray spectroscopy",
        "abstract": "Understanding protein functionality is of fundamental importance in biochemistry. Soft X-ray transitions, where the core-level vacancies are filled by the valence-orbital electrons, give direct information about the chemical bonding. Soft X-ray absorption and emission study of poly(dG) -poly(dC) in aqueous solutions can elucidate the relation between the structure and functionality of proteins. We report the N K-edge soft X-ray absorption (XAS) and resonant soft X-ray emission spectroscopy (XES) to characterize the electronic structure near the Fermi level of DNA duplexes to specify the charge migration mechanism. Since N atoms are included in only bases in DNA duplexes, the XES spectra excited from N 1s to unoccupied states purely extract the electronic orbital features of the bases in DNA. The fact that N atoms in different bonding environments form well-defined structure has been determined. The experimental findings provide the evidence for the charge-hopping and/or charge-transfer effects in understanding of electric conduction in DNA duplexes when electrons pass through the \u03c0",
        "keywords": [
            "A-T pair",
            "DNA",
            "Electronic structure",
            "G-C pair",
            "RIXS",
            "Soft X-ray absorption and emission spectroscopy"
        ],
        "venue": "Journal of Electron Spectroscopy and Related Phenomena",
        "year": 2010,
        "id": "uduqHHso"
    },
    "aPw1ftHD": {
        "authors": [
            {
                "name": "L. Zhang",
                "org": "Advanced Light Source"
            },
            {
                "name": "N. Schwertfager",
                "org": "School of Physics"
            },
            {
                "name": "T. Cheiwchanchamnangij",
                "org": "Department of Physics"
            },
            {
                "name": "X. Lin",
                "org": "Division of Theoretical Chemistry and Biology"
            },
            {
                "name": "P.-A. Glans-Suzuki",
                "org": "Advanced Light Source"
            },
            {
                "name": "L.F.J. Piper",
                "org": "Department of Physics, Applied Physics and Astronomy"
            },
            {
                "name": "S. Limpijumnong",
                "org": "School of Physics"
            },
            {
                "name": "Y. Luo",
                "org": "Hefei National Laboratory for Physical Science at the Microscale"
            },
            {
                "name": "J.F. Zhu",
                "org": "National Synchrotron Radiation Laboratory"
            },
            {
                "name": "W.R.L. Lambrecht",
                "org": "Department of Physics"
            },
            {
                "name": "J.-H. Guo",
                "org": "Advanced Light Source"
            }
        ],
        "title": "Electronic band structure of graphene from resonant soft x-ray spectroscopy: The role of core-hole effects",
        "abstract": "The electronic structure and band dispersion of graphene on SiO",
        "keywords": [
            ""
        ],
        "venue": "Physical Review B - Condensed Matter and Materials Physics",
        "year": 2012,
        "id": "aPw1ftHD"
    },
    "Omor7hn3": {
        "authors": [
            {
                "name": "R. Zhang",
                "org": "Hefei National Laboratory for Physical Sciences at the Microscale"
            },
            {
                "name": "Y. Zhang",
                "org": "Hefei National Laboratory for Physical Sciences at the Microscale"
            },
            {
                "name": "Z.C. Dong",
                "org": "Hefei National Laboratory for Physical Sciences at the Microscale"
            },
            {
                "name": "S. Jiang",
                "org": "Hefei National Laboratory for Physical Sciences at the Microscale"
            },
            {
                "name": "C. Zhang",
                "org": "Hefei National Laboratory for Physical Sciences at the Microscale"
            },
            {
                "name": "L.G. Chen",
                "org": "Hefei National Laboratory for Physical Sciences at the Microscale"
            },
            {
                "name": "L. Zhang",
                "org": "Hefei National Laboratory for Physical Sciences at the Microscale"
            },
            {
                "name": "Y. Liao",
                "org": "Hefei National Laboratory for Physical Sciences at the Microscale"
            },
            {
                "name": "J. Aizpurua",
                "org": "Material Physics Center CSIC-UPV"
            },
            {
                "name": "Y. Luo",
                "org": "Theoretical Chemistry and Biology"
            },
            {
                "name": "J.L. Yang",
                "org": "Hefei National Laboratory for Physical Sciences at the Microscale"
            },
            {
                "name": "J.G. Hou",
                "org": "Hefei National Laboratory for Physical Sciences at the Microscale"
            }
        ],
        "title": "Chemical mapping of a single molecule by plasmon-enhanced Raman scattering",
        "keywords": [
            ""
        ],
        "venue": "Nature",
        "year": 2013,
        "id": "Omor7hn3"
    },
    "V9o62U8j": {
        "authors": [
            {
                "name": "X.D. Wang",
                "org": "Key Laboratory for Precision and Non-traditional"
            },
            {
                "name": "Y. Luo",
                "org": "Key Laboratory for Precision and Non-traditional"
            },
            {
                "name": "X.W. Zhang",
                "org": "Key Laboratory for Precision and Non-traditional"
            },
            {
                "name": "L. Teng",
                "org": "Flight Automatic Control Research Institute"
            },
            {
                "name": "W.M. Yang",
                "org": "Flight Automatic Control Research Institute"
            },
            {
                "name": "L. Chen",
                "org": "Flight Automatic Control Research Institute"
            }
        ],
        "title": "Precision equipments for assembly of miniature devices: System architecture and technological approaches",
        "abstract": "To deploy precision assembly equipments quickly for manufacturing with easy implementation of the hardware and software, simple modularized assembly system architecture with functional oriented modules was established on the basis of the developed assembly equipments. The related key technology, including the equipments' system architecture and technological approaches in achieving manipulation and assembly of the parts were summarized. Some of the technological approaches, including machine vision based measurement and handling of the miniature parts, system calibration for precise assembly were described with the functional modules. \u00a9 2013 IEEE.",
        "keywords": [
            "Automatic assembly of miniature device",
            "Machine vision-based assembly system",
            "Precision assembly",
            "Precision equipments"
        ],
        "venue": "Proceedings - 2013 IEEE International Symposium on Assembly and Manufacturing, ISAM 2013",
        "year": 2013,
        "id": "V9o62U8j"
    },
    "noqUffoU": {
        "authors": [
            {
                "name": "D.Z. Wang",
                "org": "Key Laboratory for Precision and Non-traditional Machining Technology of Ministry of Education, Dalian University of Technology"
            },
            {
                "name": "Y. Li",
                "org": "Key Laboratory for Micro/Nano Technology and System of Liaoning Province, Dalian University of Technology"
            },
            {
                "name": "J.S. Liang",
                "org": "Key Laboratory for Precision and Non-traditional Machining Technology of Ministry of Education, Dalian University of Technology"
            },
            {
                "name": "Z.X. Xia",
                "org": "Dalian Institute of Chemical Physics, Chinese Academy of Sciences"
            },
            {
                "name": "S.L. Wang",
                "org": "Dalian Institute of Chemical Physics, Chinese Academy of Sciences"
            },
            {
                "name": "C. Liu",
                "org": "Key Laboratory for Precision and Non-traditional Machining Technology of Ministry of Education, Dalian University of Technology"
            },
            {
                "name": "G.Q. Sun",
                "org": "Dalian Institute of Chemical Physics, Chinese Academy of Sciences"
            },
            {
                "name": "Y. Luo",
                "org": "Key Laboratory for Precision and Non-traditional Machining Technology of Ministry of Education, Dalian University of Technology"
            },
            {
                "name": "X.D. Wang",
                "org": "Key Laboratory for Precision and Non-traditional Machining Technology of Ministry of Education, Dalian University of Technology"
            }
        ],
        "title": "Fabrication and performance of different structural cathode catalyst layers by EHDA deposition for DMFC",
        "abstract": "In this work, electrohydrodynamic atomization Layer-by-Layer deposition was used to deposit cathode catalyst layers (CLs) at different working distances of 3, 5, and 7mm. The influence of working distance on the structural characteristics of cathode CLs was analyzed. The cyclic voltammograms of the cathode electrodes with different structures and the performance of the assembled membrane-electrode assemblies (MEAs) were examined. It was observed that the cathode CLs presented well-packed and porous features. The dispersity of the deposited catalyst and the thickness of cathode CL increased with higher working distance, which resulted in larger electrochemical active surface area (ESA), higher performance of the assembled MEAs and higher catalyst utilization. The ESA increased by approximately 70% when the cathode CL produced at the working distance of 7mm compared with that at 3mm. The peak power density of 56.1mWcm",
        "keywords": [
            "Catalyst-Coated Membrane",
            "Direct Methanol Fuel Cell",
            "Electrohydrodynamic Atomization",
            "Layer-by-Layer Deposition"
        ],
        "venue": "Fuel Cells",
        "year": 2014,
        "id": "noqUffoU"
    },
    "2whYRfFe": {
        "authors": [
            {
                "name": "A. Serikov",
                "org": ""
            },
            {
                "name": "U. Fischer",
                "org": ""
            },
            {
                "name": "R. Heidinger",
                "org": ""
            },
            {
                "name": "K. Lang",
                "org": ""
            },
            {
                "name": "Y. Luo",
                "org": ""
            },
            {
                "name": "H. Tsige-Tamirat",
                "org": ""
            }
        ],
        "title": "Radiation shielding analyses for the ECRH launcher in the ITER upper port",
        "abstract": "Radiation shielding analyses have been performed for the ECRH system in the ITER upper port to complete the neutron streaming analysis performed previously. The analyses aimed at assessing and optimising the performance of the radiation shield to prove that the shielding requirements can be met by the proposed design variants. The radiation transport calculations have been performed by means of the Monte Carlo programme MCNP in 3D geometry using the standard ITER neutronics model with ECRH launcher and plug integrated into the upper port. The interface programme MCAM was used to convert the 3D ECRH launcher models available from the CAD-system for use with MCNP-calculations. It was shown that the launcher design with the proposed radiation shield can satisfy the design limits for the radiation loads to both the launcher and the neighbouring components such as the Vacuum Vessel and the TF coils. Radiation dose levels were assessed for reactor shutdown at the rear side of ECRH launcher at locations where personnel access for maintenance may be required. The shutdown dose rate calculations were also performed in 3D geometry by applying the rigorous 2-step (R2S) method and comparing the results to those obtained with the direct 1-step (D1S) method. The R2S method includes activation calculations for the launcher materials by means of the inventory code FISPACT. It was proven that the shutdown dose rates inside the port with straight waveguides will be below the ITER radiation limit of 100 \u03bdSv/hr after 10 days decay time. \u00a9 2005 IOP Publishing Ltd.",
        "keywords": [
            ""
        ],
        "venue": "Journal of Physics: Conference Series",
        "year": 2005,
        "id": "2whYRfFe"
    },
    "IIO94sNd": {
        "authors": [
            {
                "name": "A. Serikov",
                "org": "Association FZK-Euratom"
            },
            {
                "name": "U. Fischer",
                "org": "Association FZK-Euratom"
            },
            {
                "name": "Y. Chen",
                "org": "Association FZK-Euratom"
            },
            {
                "name": "K. Lang",
                "org": "Association FZK-Euratom"
            },
            {
                "name": "R. Heidinger",
                "org": "Association FZK-Euratom"
            },
            {
                "name": "Y. Luo",
                "org": "Computer and Information College"
            },
            {
                "name": "E. Stratmanns",
                "org": "Association FZK-Euratom"
            },
            {
                "name": "H. Tsige-Tamirat",
                "org": "Association FZK-Euratom"
            }
        ],
        "title": "Neutronics analysis of the ECW launching system in the ITER upper port",
        "abstract": "This paper is devoted to the neutronics analysis of the electron cyclotron wave (ECW) launching system installed in the ITER upper port. The launcher design developed by FOM Rijnhuizen with a twisted arrangement of straight waveguides was selected to facilitate the maintenance of the ECW system by avoiding mitre bends. Two types of ECW launcher designs were considered in this paper: limited and full focusing. Three dimensional MCNP models of the ECW launchers were developed with high accuracy directly from the CAD geometry models by means of an interface programme. A shielding analysis was performed to estimate the length and thickness required for the shield around the waveguides. A two-step method making use of surface sources and point detectors was applied in the neutron streaming calculations in order to estimate the radiation load on the CVD diamond window. The neutron and gamma fluxes, the nuclear heat density, and the helium production were calculated. The results show that the design limits both for the limited and the full focusing ECW models are met. \u00a9 2005 Elsevier B.V. All rights reserved.",
        "keywords": [
            "ECW heating",
            "ITER",
            "Monte Carlo calculations",
            "Neutron streaming",
            "Neutronics"
        ],
        "venue": "Fusion Engineering and Design",
        "year": 2005,
        "id": "IIO94sNd"
    },
    "RUVyPIo8": {
        "authors": [
            {
                "name": "A. Serikov",
                "org": "Association FZK-Euratom"
            },
            {
                "name": "U. Fischer",
                "org": "Association FZK-Euratom"
            },
            {
                "name": "R. Heidinger",
                "org": "Association FZK-Euratom"
            },
            {
                "name": "Y. Luo",
                "org": "Computer and Information College"
            },
            {
                "name": "H. Tsige-Tamirat",
                "org": "Association FZK-Euratom"
            }
        ],
        "title": "Radiation shielding analyses for the ITER upper port ECRH launcher",
        "abstract": "Nuclear fusion researches worldwide are focused on ITER project. A working group from various EURATOM associations is conducting R&D work on the design of the integrated ECRH launcher system for the ITER fusion reactor. ITER will use an Electron Cyclotron Resonance Heating (ECRH) system for plasma stabilization, heating, and current drive by injecting mm-wave beams. The beams injection is performed by the launcher and it requires open to plasma slots in the shield of the corresponding ITER blanket modules. The mm-waves are transmitted to the plasma through long and narrow waveguide channels. Plasma openings and channels result in enhanced neutron radiation loadings to the launcher and neighbouring components. The aim of the analyses was to prove the correspondence of ECRH launcher design to all range of nuclear criteria specified for ITER project. Nuclear criteria included human safety issues, consistency with ITER nuclear waste policy, and radiation shielding requirements. The aim was reached by evaluations of the radiation loads to sensitive components such as the diamond window of the ECRH launcher, the vacuum vessel and super-conducting magnets and the assessment of potential radiation doses to work personnel during shutdown periods. Dedicated computational approaches were developed to handle the related neutron streaming and shielding problems on the basis of 3D Monte Carlo calculations with the MCNP code using models of the launcher generated by a newly developed interface programme from the underlying CAD geometry data. The analyses results show that all radiation design limits can be safely met for the considered launcher and shield designs.",
        "keywords": [
            ""
        ],
        "venue": "American Nuclear Society's 14th Biennial Topical Meeting of the Radiation Protection and Shielding Division",
        "year": 2006,
        "id": "RUVyPIo8"
    },
    "uT3sgMge": {
        "authors": [
            {
                "name": "A. Serikov",
                "org": ""
            },
            {
                "name": "U. Fischer",
                "org": ""
            },
            {
                "name": "R. Heidinger",
                "org": ""
            },
            {
                "name": "H. Tsige-Tamirat",
                "org": ""
            },
            {
                "name": "Y. Luo",
                "org": ""
            }
        ],
        "title": "Radiation shielding analyses for the ITER upper port ECRH launcher",
        "abstract": "The International Thermonuclear Experimental Reactor (ITER) will use an electron cyclotron resonance heating (ECRH) system in the upper port of the device for plasma stabilization, heating, and current drive by injecting millimeter wave beams into the plasma chamber. The millimeter waves are transmitted to the plasma through long and narrow waveguide channels. The required plasma wall openings could result in enhanced neutron radiation loadings to the ECRH launcher and neighboring reactor components. The analyses aimed at proving that the shielding requirements and all related nuclear design limits specified by ITER can be met for the proposed ECRH launcher design concepts. The nuclear criteria included human safety issues, nuclear waste regulation aspects, and radiation shielding requirements. The proof was conducted by calculating the radiation loads to sensitive components such as the diamond window of the ECRH launcher, the vacuum vessel, and the superconducting magnets and assessing the potential radiation doses to work personnel during shutdown periods. Dedicated computational approaches were developed to handle the related neutron streaming and shielding problems on the basis of threedimensional Monte Carlo calculations by the MCNP code. Suitable MCNP models of the launcher were generated by the automatic conversion of the underlying computer assisted design models using a newly developed interface program. The results of the analyses show that all radiation design limits can be safely met for the considered launcher and shield designs.",
        "keywords": [
            "CAD to MCNP conversion interface",
            "ITER ECRH launcherneutronics",
            "Monte Carlo MCNP transport"
        ],
        "venue": "Fusion Science and Technology",
        "year": 2008,
        "id": "uT3sgMge"
    },
    "ITtwt7CH": {
        "authors": [
            {
                "name": "Y. Wu",
                "org": ""
            },
            {
                "name": "Y. Li",
                "org": ""
            },
            {
                "name": "L. Hu",
                "org": ""
            },
            {
                "name": "Y. Luo",
                "org": ""
            },
            {
                "name": "X. Gu",
                "org": ""
            },
            {
                "name": "J.Q. Wang",
                "org": ""
            },
            {
                "name": "F. Wang",
                "org": ""
            },
            {
                "name": "J. Wang",
                "org": ""
            },
            {
                "name": "T. Chen",
                "org": ""
            },
            {
                "name": "J. Qi",
                "org": ""
            }
        ],
        "title": "Development and application of a risk monitor for nuclear power plant",
        "abstract": "Risk monitor, which has been widely used in the progress of RID (Risk Informed Decision) in a NPP (Nuclear Power Plant), is a plant specific real-time analysis tool to determine the instantaneous risk based on actual plant configuration. Based on wide investigation of challenges and technical issues during the development of a risk monitor, a prototype named Risk Angel has been designed by FDS Team in collaboration with several institutes and universities. An overview of the architecture and main functions of Risk Angel were introduced in this paper, as well as the quantitative approach, the calculating engine and the model development. Risk Angel has been applied in a nuclear power plant in P.R. China.",
        "keywords": [
            "Nuclear power plant",
            "Probabilistic safety assessment",
            "Risk informed decision",
            "Risk monitor"
        ],
        "venue": "10th International Conference on Probabilistic Safety Assessment and Management 2010, PSAM 2010",
        "year": 2010,
        "id": "ITtwt7CH"
    },
    "XjGfxx1B": {
        "authors": [
            {
                "name": "X.Q. Zhu",
                "org": "Department of Plant Pathology"
            },
            {
                "name": "X.Y. Chen",
                "org": "Beijing Plant Protection Station"
            },
            {
                "name": "Y. Luo",
                "org": "Department of Plant Pathology"
            },
            {
                "name": "L.Y. Guo",
                "org": "Department of Plant Pathology"
            }
        ],
        "title": "First report of Monilinia fructicola on peach and nectarine in China",
        "abstract": "",
        "keywords": [
            ""
        ],
        "venue": "Plant Pathology",
        "year": 2005,
        "id": "XjGfxx1B"
    },
    "ss1WVK8K": {
        "authors": [
            {
                "name": "Y. Luo",
                "org": ""
            },
            {
                "name": "Z. Ma",
                "org": ""
            },
            {
                "name": "H.C. Reyes",
                "org": ""
            },
            {
                "name": "D. Morgan",
                "org": ""
            },
            {
                "name": "T.J. Michailides",
                "org": ""
            }
        ],
        "title": "Quantification of airborne spores of Monilinia fructicola in stone fruit orchards of California using real-time PCR",
        "abstract": "The fungal pathogen Monilinia fructicola causes blossom blight and fruit brown rot of stone fruits in California. In this study, spore densities in the air were monitored in six orchard/year combinations with Burkard spore traps. A real-time PCR assay was developed to efficiently quantify the dynamics of spore density in these orchards during the growing season. Different patterns of dynamics of spore density were observed in these orchards. A linear relationship between numbers of spores counted with a compound microscope and those determined with the real-time PCR assay was obtained, using the same samples of spore traps. Spore density in five of six orchard/year combinations ranged from 0.0 to 0.05 spores 1",
        "keywords": [
            "Epidemiology",
            "Inoculum",
            "Prunus spp.",
            "Spore quantification"
        ],
        "venue": "European Journal of Plant Pathology",
        "year": 2007,
        "id": "ss1WVK8K"
    },
    "cXHnv2qv": {
        "authors": [
            {
                "name": "Y.F. Zhong",
                "org": "Department of Plant Pathology"
            },
            {
                "name": "Y.W. Zhang",
                "org": "Department of Plant Pathology"
            },
            {
                "name": "X.Y. Chen",
                "org": "Department of Plant Pathology"
            },
            {
                "name": "Y. Luo",
                "org": "Department of Plant Pathology"
            },
            {
                "name": "L.Y. Guo",
                "org": "Department of Plant Pathology"
            }
        ],
        "title": "Overwintering of Monilinia fructicola in stone fruit orchards in northern China",
        "abstract": "Survival of Monilinia fructicola on the surface of mummified fruit and in peduncles and shoots of stone fruit trees infected by M. fructicola in the previous season was studied from 2003 to 2006 in orchards in the agricultural region of Beijing. Viable conidia of M. fructicola were consistently detected on fruit mummies from mid-March to the end of April. During flowering (in mid-April), studies in five peach orchards showed that 33-87% of mummified fruit bore viable conidia. The germination rate of conidia on diseased fruit was about 64% in autumn. It decreased to 24% in mid-winter when the fruit was completely mummified, and in the following year to 2-4% in early spring. Viable M. fructicola was consistently detected in peach and nectarine shoots collected in winter and spring. In general, viable M. fructicola in peduncles was detected from mummified fruit of 11-27% branches and from asymptomatic plant tissues of 3-20% branches. Sporulation of M. fructicola was observed on peduncles in seven of eight surveys, and the percentage of branches containing viable M. fructicola in peduncles in contact with mummified fruits ranged from 18% to 40%. This study demonstrates that the tree-borne mummified fruit and the peduncles could be the parts of trees where M. fructicola can survive the winter in orchards in suburban Beijing. \u00a9 2008 The Authors.",
        "keywords": [
            "Brown rot",
            "Monilinia fructicola",
            "Prunus spp."
        ],
        "venue": "Journal of Phytopathology",
        "year": 2008,
        "id": "cXHnv2qv"
    },
    "jk3BqsEg": {
        "authors": [
            {
                "name": "S.-M. Zeng",
                "org": "Department of Plant Pathology"
            },
            {
                "name": "Y. Luo",
                "org": "Department of Plant Pathology"
            }
        ],
        "title": "Systems analysis of wheat stripe rust epidemics in China",
        "abstract": "Stripe rust is the most destructive disease of wheat in China and shows long-distance spread with interregional epidemics. Systems analysis had been implemented by the epidemiology group at the China Agricultural University to study the epidemiology of this disease from field to regional levels. This paper reviews major achievements by this group from the 1970s to the present in this pathosystem in China. Field experiments were conducted to obtain necessary parameters for constructing various simulation models. Field-level models were generated to study the spatial and temporal disease developments, while region-level models were developed to study the disease long-distance spread, interregional epidemics and strategies for disease management. Interactions between host, pathogen and environment were also studied with modelling approaches to generate information on deployment of resistance for regional disease management. \u00a9 2007 KNPV.",
        "keywords": [
            "Disease management",
            "Epidemiology",
            "Modelling",
            "Puccinia striiformis",
            "Resistance"
        ],
        "venue": "European Journal of Plant Pathology",
        "year": 2008,
        "id": "jk3BqsEg"
    },
    "MpqTUtXQ": {
        "authors": [
            {
                "name": "Y. Luo",
                "org": ""
            },
            {
                "name": "W. Gao",
                "org": ""
            },
            {
                "name": "M. Doster",
                "org": ""
            },
            {
                "name": "T.J. Michailides",
                "org": ""
            }
        ],
        "title": "Quantification of conidial density of aspergillus flavus and a parasiticus in soil from almond orchards using real-time PCR",
        "abstract": "Aims: To design the Aspergillus flavus and Aspergillus parasiticus-specific primers and a real-time PCR assay for quantification of the conidial density in soil. Methods and Results: Aspergillus flavus and A. parasiticus-specific DNA primers were designed based on internal transcribed spacer sequences to distinguish these two species and from other Aspergillus and other fungal species. A method of pathogen DNA extraction directly from soil samples was developed. Using the designed primers, a real-time PCR assay was developed to quantitatively determine the conidial density of each A. flavus and A. parasiticus in soil, after generating corresponding standard curves. Known conidial densities of each A. flavus or A. parasiticus in soil significantly correlated with those tested with the real-time PCR. Conclusions: This study demonstrated the applicability of the real-time PCR assay in studies of quantifying A. flavus and A. parasiticus in soil as inoculum sources. Significance and Impact of the Study: The A. flacus and A. parasitic-specific primers can be widely used in aflatoxin research. The real-time PCR assay developed in this study provides a potential approach to quantify the plant pathogen density from not only soil but also other sources in relation to aflatoxin contamination from environment, food and feed commodities. \u00a9 2009 The Society for Applied Microbiology.",
        "keywords": [
            "Aflatoxin",
            "Fungi",
            "Internal transcribed spacer",
            "Quantification",
            "Real-time PCR",
            "Soil"
        ],
        "venue": "Journal of Applied Microbiology",
        "year": 2009,
        "id": "MpqTUtXQ"
    },
    "a78gTl45": {
        "authors": [
            {
                "name": "A.-H. Cai",
                "org": ""
            },
            {
                "name": "H. Chen",
                "org": ""
            },
            {
                "name": "W.-K. An",
                "org": ""
            },
            {
                "name": "W.-X. Liu",
                "org": ""
            },
            {
                "name": "Y. Luo",
                "org": ""
            },
            {
                "name": "T.-L. Li",
                "org": ""
            },
            {
                "name": "M. Chen",
                "org": ""
            }
        ],
        "title": "Robust optimisation of chemical composition of as cast chromium white cast iron using a green sand mould",
        "abstract": "An L",
        "keywords": [
            "Artificial neural network",
            "Chemical composition",
            "Chromium white cast iron",
            "Orthogonal design"
        ],
        "venue": "Materials Science and Technology",
        "year": 2008,
        "id": "a78gTl45"
    },
    "6dYXVpaS": {
        "authors": [
            {
                "name": "A.H. Cai",
                "org": "Department of Mechanical and Electrical Engineering"
            },
            {
                "name": "X. Xiong",
                "org": "State Key Laboratory of Powder Metallurgy"
            },
            {
                "name": "Y. Liu",
                "org": "State Key Laboratory of Powder Metallurgy"
            },
            {
                "name": "H. Chen",
                "org": "Department of Mechanical and Electrical Engineering"
            },
            {
                "name": "W.K. An",
                "org": "Department of Mechanical and Electrical Engineering"
            },
            {
                "name": "X.S. Li",
                "org": "Department of Mechanical and Electrical Engineering"
            },
            {
                "name": "Y. Zhou",
                "org": "Department of Mechanical and Electrical Engineering"
            },
            {
                "name": "Y. Luo",
                "org": "Department of Mechanical and Electrical Engineering"
            }
        ],
        "title": "Estimation of Kauzmann temperature and isenthalpic temperature of metallic glasses",
        "abstract": "We propose expressions for the estimation of the isenthalpic temperature T ",
        "keywords": [
            "61.43.Er Other amorphous solids",
            "63.50.Lm Glasses and amorphous solids",
            "64.70.pe Metallic glasses",
            "65.60.+a Thermal properties of amorphous solids and glasses: heat capacity, thermal expansion, etc."
        ],
        "venue": "European Physical Journal B",
        "year": 2008,
        "id": "6dYXVpaS"
    },
    "0pEk5hxj": {
        "authors": [
            {
                "name": "W.K. An",
                "org": "Department of Mechanical and Electrical Engineering"
            },
            {
                "name": "A.H. Cai",
                "org": "State Key Laboratory of Powder Metallurgy"
            },
            {
                "name": "J.H. Li",
                "org": "State Key Laboratory of Powder Metallurgy"
            },
            {
                "name": "Y. Luo",
                "org": "Department of Mechanical and Electrical Engineering"
            },
            {
                "name": "T.L. Li",
                "org": "Department of Mechanical and Electrical Engineering"
            },
            {
                "name": "X. Xiong",
                "org": "State Key Laboratory of Powder Metallurgy"
            },
            {
                "name": "Y. Liu",
                "org": "State Key Laboratory of Powder Metallurgy"
            },
            {
                "name": "Y. Pan",
                "org": "College of Materials Science and Engineering"
            }
        ],
        "title": "Glass formation and non-isothermal crystallization of Zr62.5Al12.1Cu7.95Ni17.45 bulk metallic glass",
        "abstract": "Glass forming ability (GFA) and non-isothermal crystallization kinetics of Zr",
        "keywords": [
            "Amorphous metals",
            "Crystallization",
            "Glass formation",
            "Metallic glasses",
            "Thermodynamics"
        ],
        "venue": "Journal of Non-Crystalline Solids",
        "year": 2009,
        "id": "0pEk5hxj"
    },
    "hBSDLOic": {
        "authors": [
            {
                "name": "W.K. An",
                "org": "Department of Mechanical and Electrical Engineering"
            },
            {
                "name": "X. Xiong",
                "org": "State Key Laboratory of Powder Metallurgy"
            },
            {
                "name": "Y. Liu",
                "org": "State Key Laboratory of Powder Metallurgy"
            },
            {
                "name": "J.H. Li",
                "org": "State Key Laboratory of Powder Metallurgy"
            },
            {
                "name": "A.H. Cai",
                "org": "State Key Laboratory of Powder Metallurgy"
            },
            {
                "name": "Y. Luo",
                "org": "Department of Mechanical and Electrical Engineering"
            },
            {
                "name": "T.L. Li",
                "org": "Department of Mechanical and Electrical Engineering"
            },
            {
                "name": "X.S. Li",
                "org": "Department of Mechanical and Electrical Engineering"
            }
        ],
        "title": "Investigation of glass forming ability and crystallizat